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Mathematical Model for Predicting Arterial Drug Diffusion from Drug-Eluting Stents 预测药物洗脱支架动脉药物扩散的数学模型
Q4 Computer Science Pub Date : 2014-02-01 DOI: 10.14355/IJCSA.2014.0301.08
Carrie V. Falke, A. Khaliq, T. Dugas, J. Kleinedler, W. Dai
Arterial blockages are a common and significant clinical problem. One clinical method to clear these blockages is to deploy drug-eluting stents (DES) to restore blood flow through a narrowed artery. However, the design of a DES poses a unique challenge, because the concentration of drug within the arterial tissue must be therapeutically sufficient to interrupt the pathogenesis of restenosis. Characterizing the factors that determine drug kinetics and partitioning within the arterial wall is of paramount importance, especially when delivering drugs with narrow safety margins. This article presents a three-dimensional mathematical model for accurately predicting arterial drug concentration and flux after the drug is released from a stent, so that drug-eluting stents can be designed more efficiently to treat arterial blockages. The mathematical model is then solved using the COMSOL solver.
动脉阻塞是一个常见而重要的临床问题。清除这些阻塞的一种临床方法是部署药物洗脱支架(DES)来恢复狭窄动脉的血液流动。然而,DES的设计提出了一个独特的挑战,因为动脉组织内的药物浓度必须足以治疗中断再狭窄的发病机制。表征决定药物动力学和动脉壁内分配的因素是至关重要的,特别是在输送安全边际较窄的药物时。本文提出了一种准确预测药物从支架中释放后动脉药物浓度和通量的三维数学模型,以便更有效地设计药物洗脱支架来治疗动脉阻塞。然后用COMSOL求解器对数学模型进行求解。
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引用次数: 0
Research and Implementation of Distributed Disaster Tolerant System 分布式容灾系统的研究与实现
Q4 Computer Science Pub Date : 2014-02-01 DOI: 10.14355/ijcsa.2014.0301.11
Yongjian Ren, Hui Xuan, Jilin Zhang, Yuyu Yin, Miaofeng Shi
With the advent of the information age, the growths of data amount are explosive in various industries and the importance of data is becoming more and more prominent. When a disaster occurs, how to recover data completely and rapidly is one of the important issues which raised common concern in both industry and academy. This paper proposes a distributed disaster tolerant system based on information decentralization algorithm. The system, called NewDDR, adopts distributed architecture to ensure the high availability of data even under the condition of multi-node damage and continuous disaster. NewDDR uses considerably fewer physical resources by employing the information decentralization algorithm which is based on erasure codes. Experiments show that NewDDR can guarantee effective protection of data and business , while not affect the normal operation of the application.
随着信息时代的到来,各行各业的数据量呈爆发式增长,数据的重要性日益凸显。当灾难发生时,如何完整、快速地恢复数据是工业界和学术界共同关注的重要问题之一。提出了一种基于信息分散算法的分布式容灾系统。该系统被称为NewDDR,采用分布式架构,即使在多节点破坏和持续灾难的情况下也能保证数据的高可用性。NewDDR通过采用基于擦除码的信息去中心化算法,大大减少了物理资源的使用。实验表明,在不影响应用正常运行的情况下,NewDDR能够保证数据和业务的有效保护。
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引用次数: 0
Dynamic Analysis and Optimization of Parallel Manipulator 并联机器人的动力学分析与优化
Q4 Computer Science Pub Date : 2014-02-01 DOI: 10.14355/IJCSA.2014.0301.10
W. Kai-jie, Wu Jianxin
Electromechanical coupling dynamic model of parallel manipulator is a kind of a complicated electromechanical system which is multi‐input, multi‐output, nonlinear and strong coupling. There is not a perfect method to calculate dynamic modeling and simulation of parallel manipulator at present. 6UPS‐parallel manipulator dynamic model was set up by Lagrange method; PID position controller was designed; and the controller parameters were optimized by inertia weight adaptive particle swarm optimization in the article. It was proved that the modeling of electromechanical coupling dynamic model was right and the manipulator was controlled well by the controller through the simulation result of computer.
并联机械臂机电耦合动力学模型是一种多输入、多输出、非线性、强耦合的复杂机电系统。目前还没有一种完善的方法来计算并联机械臂的动力学建模和仿真。采用拉格朗日法建立了6UPS -并联机械臂动力学模型;设计了PID位置控制器;采用惯性权值自适应粒子群算法对控制器参数进行了优化。计算机仿真结果表明,所建立的机电耦合动力学模型是正确的,控制器能很好地控制机械手。
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引用次数: 0
The Coupling Analysis and Research of Temperature and flow Field 温度与流场耦合分析与研究
Q4 Computer Science Pub Date : 2014-02-01 DOI: 10.14355/IJCSA.2014.0301.09
Wang Lin, Wu Jianxin
To the solid rocket axisymmetric thrust‐vectoring nozzle, under the action of flow field and temperature field, Comsol Multiphysics is used for this mechanism to simulate the load deformation and thermal deformation of the convergent plate, sheet, rod expansion regulation and other components, and to analyze the dynamic characteristics of the system in the generator mode under the two field coupling. Simulation and analysis to forecast the deformation of the mechanism accurately have important theoretical significances to the design of the system.
针对固体火箭轴对称推力矢量喷管,采用Comsol Multiphysics软件对该机构在流场和温度场作用下的载荷变形和热变形进行了模拟,分析了两场耦合作用下系统在发电机模式下的动态特性。通过仿真分析准确预测机构的变形,对系统的设计具有重要的理论意义。
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引用次数: 0
Technology Adoption and Trademarks 技术采用和商标
Q4 Computer Science Pub Date : 2014-02-01 DOI: 10.14355/IJCSA.2014.0301.14
A. Saleem, Kiyohide Higuchi
Technology adoption in Industries and firms is the current quest. Business sector growth is the current quest in the global market. Intellectual Property (IP) rights data is the indicator for the research and development in the business sector. Patents have gained attraction as indicator by researchers to analyses technology adoption, Research and Development (R & D) and the economic growth. However, trademark is relatively new concept to use it for economic analysis. Trademarks are the most prominent type of Intellectual Property used in most of the developed and developing countries. The analysis used secondary data from different sources. We downloaded trademark data from the WIPO (World Intellectual Property Organization), Goods and Services data from the United Nations Statistics Division, and OECD database. This study is important in spite of its analysis difficulties. This study is in depth analysis of the trademark that distinguishes the role of trademark as technology adoption indicator. This study is twofold. Firstly describes the details about trademark classification. Secondly, it indicate the technology adoption trend by using trademark data.
在工业和企业中采用技术是当前的追求。商业部门的增长是当前全球市场的追求。知识产权(IP)权利数据是商业部门研究和开发的指标。专利作为分析技术采用、研发和经济增长的指标越来越受到研究者的关注。然而,将商标用于经济分析是一个相对较新的概念。商标是大多数发达国家和发展中国家使用的最主要的知识产权类型。该分析使用了来自不同来源的二手数据。我们从WIPO(世界知识产权组织)下载了商标数据,从联合国统计司下载了商品和服务数据,从经合组织数据库下载了数据。尽管这项研究在分析上有困难,但它很重要。本研究对商标进行了深入分析,区分了商标作为技术采用指标的作用。这项研究是双重的。首先介绍了商标分类的具体内容。其次,利用商标数据表明技术的采用趋势。
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引用次数: 1
An AHP (Analytic Hierarchy Process)/FCE (Fuzzy Comprehensive Evaluation)-Based Multi-Criteria Decision Approach for Looking for the Best All Time College Coaches 基于层次分析法/模糊综合评价法的多准则选拔最佳高校专职教练员方法
Q4 Computer Science Pub Date : 2014-01-01 DOI: 10.5121/IJCSA.2014.4308
Jin-qiu Lv, Xiaoming You, Wenjie Shen, Sheng Liu
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引用次数: 0
Anaphora Resolution in Hindi Language Using Gazetteer Method 用地名法解析印地语的回指
Q4 Computer Science Pub Date : 2014-01-01 DOI: 10.5121/IJCSA.2014.4307
Smita Singh, Priya Lakhmani, Pratistha Mathur, Sudha Morwal
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引用次数: 8
Using Inhomogeneity of Heterostructure and Optimization of Annealing to Decrease Dimensions Multyemitter Heterotransistors 利用异质结构的非均匀性和退火的优化减小多发射极异质晶体管的尺寸
Q4 Computer Science Pub Date : 2014-01-01 DOI: 10.5121/ijcsa.2014.4303
E. Pankratov, E. Bulaeva
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引用次数: 0
Effect of Mesh Grid Structure In Reducing "Hot Carrier Effect" of Nmos Device Simulation 网格结构在减少Nmos器件仿真“热载子效应”中的作用
Q4 Computer Science Pub Date : 2014-01-01 DOI: 10.5121/IJCSA.2014.4311
Khomdram Jolson Singh, T. Thingujam, Laishram Bidyapati Devi, N. Singh, S. Sarkar
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引用次数: 0
LABVIEW WITH DWT FOR DENOISING THE BLURRED BIOMETRIC IMAGES Labview用DWT去噪模糊的生物特征图像
Q4 Computer Science Pub Date : 2014-01-01 DOI: 10.5121/IJCSA.2014.4301
Fadhil A. Ali
In this paper, biometric blurred image(fingerprint) denoising are presented a nd investigated by using LabVIEW applications , It is blurred and corrupted with Gaussian noise. This work is proposed algorithm that has used a discrete wavelet transform (DWT) to divide the image into two parts, this will be increasing the manipulation speed of biometric images that are of the big sizes.This work has included two tasks ; the first designs the LabVIEW system to calculate and present the approximation coefficients, by which the image's blur factor reduced to minimum value accord ing to the proposed algorithm. The second task removes the image's noise by calculated the regression coefficients according to BayesianShrinkage estimation method.
本文提出了一种生物特征模糊图像(指纹)的去噪方法,并利用LabVIEW应用程序对其进行了研究。本工作提出了一种利用离散小波变换(DWT)将图像分成两部分的算法,这将提高大尺寸生物特征图像的处理速度。这项工作包括两项任务;首先设计LabVIEW系统,计算并给出近似系数,使图像的模糊系数根据所提出的算法减小到最小。第二步,根据贝叶斯收缩估计方法计算回归系数,去除图像噪声。
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引用次数: 1
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