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Case Report of Fibrocartilaginous Embolic Myelopathy of the Spinal Cord in a Female Dog 雌性犬脊髓纤维软骨栓塞性脊髓病1例报告
Q4 Veterinary Pub Date : 2022-09-25 DOI: 10.58803/saa.v1i1.1
Sina Salavati, Muhammad H Kafrashi, D. Babazadeh, M. Raznahan
Introduction: Fibrocartilaginous embolic myelopathy is a non-progressive injury in the spinal cord that can cause infarction in veins of spinal parenchyma which leads to ischemia and necrosis. Case report: Fibrocartilaginous embolic myelopathy was diagnosed in a 4-year-old, female, Spitz dog using the clinical neurological examination. The dog was hospitalized, and the treatment including supportive treatment and Cortone was set up for three weeks. Then Diazepam and Methocarbamol were added to the prescription and treatment continued for two weeks. A general improvement was noted after three weeks, and the dog could stand perfectly after 5 weeks. Conclusion: Three weeks of supportive treatment, Cortone therapy as well as the addition of Diazepam and Methocarbamol to the treatment could help the dog to stand on its feet. However, cannot be ignored that knowing about the history of the dog played an important role in its treatment procedure.
纤维软骨栓塞性脊髓病是一种非进行性脊髓损伤,可引起脊髓实质静脉梗死,导致缺血和坏死。病例报告:纤维软骨栓塞性脊髓病被诊断为4岁,女性,斯皮兹犬通过临床神经学检查。这只狗被送进了医院,接受了包括支持治疗和Cortone在内的为期三周的治疗。然后在处方中加入安定和甲氨甲氨基酚,持续治疗2周。三周后,总体情况有所改善,五周后,狗可以完全站立。结论:经3周的支持治疗、Cortone治疗及在治疗中加用安定和甲氨甲氨基酚,可使犬站起来。然而,不能忽视的是,了解狗的历史在其治疗过程中发挥了重要作用。
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引用次数: 0
Phenotypic Resistance of Staphylococcus aureus to Antibiotics in Dogs of Tamale Metropolis, Ghana 加纳塔马利大都会犬金黄色葡萄球菌对抗生素的表型耐药
Q4 Veterinary Pub Date : 2022-09-25 DOI: 10.58803/saa.v1i1.4
F. Adzitey, Nicholas Prah, Hafiz Salifu, D. Yidana
Introduction: Staphylococcus aureus is an important bacterium which induces a wide range of diseases. Its presence in dogs and resistance to antibiotics is a threat to public health due to the close association of humans with dogs. The objective of the present study was to determine the phenotypic resistance of Staphylococcus aureus (S. aureus) to antibiotics in dogs without any clinical manifestation of diseases in Tamale Metropolis, Ghana. The current study also examined microbial load in these dogs. Materials and methods: A total of 120 samples from various parts of dogs, including the mouth, nose, anus, inner ear, and outer ear, were examined. Isolation and antibiotic resistance of S. aureus were determined using the USA Bacteriological Analytical Manual and the Disc Diffusion method, respectively. Results: The presence of S. aureus in the dogs ranged from 8.3% (anus) to 58.3% (nose), averaging 40%. The microbial load also ranged from 2.9 log cfu/cm2 (mouth) to 3.4 log cfu/cm2 (outer ear) with an average of 3.2 log cfu/cm2. There were significant differences among the examined samples regarding the presence of S. aureus, but not the microbial load. The overall resistance, intermediate resistance, and susceptibility of S. aureus were 46.2%, 12.9%, and 42.2%, respectively. The S. aureus was highly resistant to teicoplanin (88.0%) and susceptible to chloramphenicol (72.0%). The multiple antibiotic indexes ranged from 0 to 0.9, and 89.1% of the isolates exhibited multidrug resistance. Conclusion: The findings of the current study revealed that healthy dogs in Tamale Metropolis, Ghana, were carriers of S. aureus as well as other bacteria, and the S. aureus exhibited different resistance patterns to antibiotics.
简介:金黄色葡萄球菌是引起多种疾病的重要细菌。由于人类与狗的密切联系,它在狗身上的存在和对抗生素的耐药性对公众健康构成威胁。本研究的目的是确定加纳Tamale大都会无任何临床疾病表现的狗的金黄色葡萄球菌(金黄色葡萄球菌)对抗生素的表型抗性。目前的研究还检查了这些狗的微生物负荷。材料与方法:选取犬口、鼻、肛门、内耳、外耳等各部位共120份标本进行检测。金黄色葡萄球菌的分离和耐药性分别采用美国细菌学分析手册和纸片扩散法进行测定。结果:犬中金黄色葡萄球菌的检出率为8.3%(肛门)~ 58.3%(鼻子),平均为40%。微生物负荷也从2.9 log cfu/cm2(口腔)到3.4 log cfu/cm2(外耳)不等,平均为3.2 log cfu/cm2。在检查的样品中,金黄色葡萄球菌的存在有显著差异,但微生物负荷没有显著差异。金黄色葡萄球菌的总耐药率为46.2%,中间耐药率为12.9%,敏感率为42.2%。金黄色葡萄球菌对替柯planin高度耐药(88.0%),对氯霉素敏感(72.0%)。多重耐药指数在0 ~ 0.9之间,89.1%的菌株表现出多重耐药。结论:本研究结果表明,加纳Tamale Metropolis的健康犬是金黄色葡萄球菌和其他细菌的携带者,金黄色葡萄球菌对抗生素表现出不同的耐药模式。
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引用次数: 0
Comparative Histopathologic Evaluation of the Effects of Portulaca oleracea, Omega-3, and Combination of Sodium Selenite and Vitamin E on Hepatic Enzymes of Experimental Diabetic Rats 马齿苋、Omega-3及亚硒酸钠和维生素E联合对实验性糖尿病大鼠肝酶影响的组织病理学比较
Q4 Veterinary Pub Date : 2022-09-25 DOI: 10.58803/saa.v1i1.2
D. Babazadeh, A. Shabestari Asl, A. Sadeghi, M. Saeed, Arman Moshavery
Introduction: Portulaca oleracea (PO) plant, Omega 3, and Sodium Selenite plus Vitamin E have antidiabetic effects by compensating for the deficiency in insulin release and enhancing antioxidant status. The purpose of the present study was to comparatively assess the effect of Portulaca oleracea, omega-3, and a combination of Sodium Selenite and Vitamin E on hepatic enzyme activities in streptozotocin-induced diabetic Rats. Materials and methods: A total of 48 adult male Wistar rats (weighing approximately 220 ± 10 g) were injected by a single intraperitoneal injection of streptozotocin (60 mg/kg body weight.) and were randomly assigned to 4 groups, and 4 replicates for each group. Group 1 served as diabetic control, groups 2, 3, and 4 received Portulaca oleracea extract (1.5 mg/kg/day, orally), Omega-3 (500 mg/kg/day, orally), and Sodium Selenite (0.5 mg/kg/day, orally) plus Vitamin E (400 Iu/kg/day, orally), respectively, for 28 days. At the end of the study, blood samples were taken for biochemical investigations. Results: The levels of blood glucose, AST, ALP, and GGT enzymes in all treatment groups were less than those of the control group. The ALT enzyme activity in rats treated with Portulaca oleracea and Vitamin E plus Selenium was less than in control and omega-3 treatment groups. Conclusion: Results indicated that Portulaca oleracea is more effective in hepatic enzyme activities of diabetic rats, compared to other treatment groups.
简介:马齿苋(porulaca oleracea, PO)植物、Omega - 3和亚硒酸钠加维生素E通过补偿胰岛素释放不足和增强抗氧化状态而具有抗糖尿病作用。本研究的目的是比较评估马齿苋、omega-3以及亚硒酸钠和维生素E联合使用对链脲佐菌素诱导的糖尿病大鼠肝酶活性的影响。材料与方法:选用体重约220±10 g的成年雄性Wistar大鼠48只,单次腹腔注射链脲佐菌素(60 mg/kg体重),随机分为4组,每组4个重复。1组作为糖尿病对照组,2、3、4组分别给予马齿苋提取物(1.5 mg/kg/d,口服)、Omega-3提取物(500 mg/kg/d,口服)、亚硒酸钠(0.5 mg/kg/d,口服)加维生素E (400 Iu/kg/d,口服),连用28 d。在研究结束时,采集血样进行生化检查。结果:各治疗组患者血糖、AST、ALP、GGT水平均低于对照组。马齿苋和维生素E加硒组大鼠的ALT酶活性低于对照组和omega-3组。结论:马齿苋对糖尿病大鼠肝酶活性的影响优于其他治疗组。
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引用次数: 0
Why Do Antibiotics Fail? A Veterinary Perspective 抗生素为什么会失败?兽医视角
Q4 Veterinary Pub Date : 2022-09-25 DOI: 10.58803/saa.v1i1.3
Andreia Garcês
In both human and veterinary medicine, the failure of apparently appropriate antimicrobial therapy is a common and often exasperating clinical problem. Many factors are associated with the failure of antibiotic therapy, including an incorrect diagnosis of infectious disease, selection of the inappropriate antibiotic, and incorrect dosage. To achieve the best results, bacteriological diagnostics in the laboratory should be made. Even though the in-vitro antimicrobial susceptibility testing guides the potentially suitable antimicrobials, the in-vitro susceptibility obtained is not always the best in-vivo. The clinician should be aware of other factors, including biofilm-forming bacteria, physicochemical conditions at the site of infection (such as perfusion rate, oxygen partial pressure, and pH value), or immunosuppression of the patient that can lead to failure of the treatment. This review summarized the main factors associated with antibiotic failure in a veterinarian practice. In a world where animal and human resistance to an antibiotic is rising every year, rational and efficient use of antibiotic therapy is of utmost importance. It is essential to continue with the education of veterinary practitioners in all aspects of antimicrobial resistance and treatment to improve future treatments and have a more rational use of antibiotics to reduce antibiotic resistance in animals and humans.
在人类和兽医学中,显然适当的抗菌治疗失败是一个常见的,往往令人恼火的临床问题。许多因素与抗生素治疗的失败有关,包括对传染病的错误诊断、选择不适当的抗生素和不正确的剂量。为达到最佳效果,应在实验室进行细菌学诊断。尽管体外药敏试验指导了潜在合适的抗菌素,但获得的体外药敏并不总是最好的体内药敏。临床医生应注意其他可能导致治疗失败的因素,包括形成生物膜的细菌、感染部位的物理化学条件(如灌注率、氧分压和pH值)或患者的免疫抑制。这篇综述总结了在兽医实践中与抗生素失效相关的主要因素。在一个动物和人类对抗生素的耐药性每年都在上升的世界里,合理和有效地使用抗生素治疗是至关重要的。必须继续在抗菌素耐药性和治疗的各个方面对兽医从业人员进行教育,以改进未来的治疗方法,并更合理地使用抗生素,以减少动物和人类的抗生素耐药性。
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引用次数: 1
Survival of cats with mediastinal cysts 患有纵隔囊肿的猫的存活率
Q4 Veterinary Pub Date : 2020-12-01 DOI: 10.1016/j.asams.2020.12.007
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引用次数: 0
Determination of the lateral extent of the wound bed in cadavers to replicate tumor excision 确定尸体伤口床的横向范围以复制肿瘤切除
Q4 Veterinary Pub Date : 2020-12-01 DOI: 10.1016/j.asams.2020.12.008
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引用次数: 0
Fecal short-chain fatty acid and dysbiosis in dogs with chronic enteropathy 慢性肠病犬粪便短链脂肪酸与生态失调
Q4 Veterinary Pub Date : 2020-12-01 DOI: 10.1016/j.asams.2020.12.004
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引用次数: 0
Plasma renin activity and aldosterone in dogs with portosystemic collaterals 门静脉络病犬血浆肾素活性和醛固酮
Q4 Veterinary Pub Date : 2020-12-01 DOI: 10.1016/j.asams.2020.12.006
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引用次数: 0
A Review on Abdominal Point-of-Care Ultrasound 腹部即时超声技术综述
Q4 Veterinary Pub Date : 2020-12-01 DOI: 10.1016/j.asams.2020.12.001
Brittany Curtis DVM, Adesola Odunayo DVM, MS, DACVECC
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引用次数: 0
Bile duct obstruction associated with pancreatitis in dogs 胆管梗阻与犬胰腺炎相关
Q4 Veterinary Pub Date : 2020-12-01 DOI: 10.1016/j.asams.2020.12.003
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Advances in Small Animal Medicine and Surgery
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