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Management of periprosthetic infection in total hip arthroplasty 全髋关节置换术中假体周围感染的处理
Q4 Medicine Pub Date : 2026-01-19 DOI: 10.1016/j.mporth.2025.11.003
James Li, Fares S Haddad
Periprosthetic infections of the hip are difficult complications to manage, associated with high morbidity and mortality and a significant resource burden to the health system. Diagnosis can be challenging, with no universally agreed definition or diagnostic criteria. Timely and accurate diagnosis requires a low index of suspicion and the careful interpretation of clinical, serological, microbiological and radiological investigations combined. Similarly, surgical management can be prolonged, with multiple procedures and long hospital admissions. The options include antibiotic suppression, debridement and implant retention, single stage revision, multi-stage revision and amputation. Successful management requires a multidisciplinary patient-centred approach, with treatment strategies tailored to the unique combination of host, microbiological and anatomical factors in each case. Patients are often left with poor functional outcomes even after infection control. Failure of surgical managements remains catastrophic. The literature on periprosthetic hip infection is heterogenous, with very little level I and II evidence available. Further research is required to produce high level evidence that can be used to guide our diagnostic and treatment pathways.
髋关节假体周围感染是难以控制的并发症,与高发病率和死亡率相关,并对卫生系统造成重大资源负担。诊断可能具有挑战性,没有普遍认可的定义或诊断标准。及时和准确的诊断需要低怀疑指数和仔细解释临床,血清学,微生物学和放射学调查相结合。同样,手术治疗可能会延长,有多个程序和长期住院。选择包括抗生素抑制,清创和种植体保留,单期翻修,多期翻修和截肢。成功的管理需要多学科的以患者为中心的方法,治疗策略根据每个病例的宿主、微生物和解剖学因素的独特组合量身定制。即使在感染得到控制后,患者的功能也常常很差。手术治疗的失败仍然是灾难性的。关于假体周围髋关节感染的文献是不一致的,很少有I级和II级的证据。需要进一步的研究来提供高水平的证据,以指导我们的诊断和治疗途径。
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引用次数: 0
The future of total hip arthroplasty 全髋关节置换术的未来
Q4 Medicine Pub Date : 2025-12-26 DOI: 10.1016/j.mporth.2025.11.004
Humza Tariq Osmani, Fares S Haddad
Over 100,000 total hip arthroplasties (THA) are performed in the UK per annum. The number continues to rise globally. Outcomes remain good, however, issues include malposition of implants, chronic pain and up to 12% dissatisfaction. Successful total THA necessitates accurate placement of implants to ensure restoration of optimal biomechanics. This review assesses potential strategies into the future which will help surgeons achieve these goals through the use robotics, digital technology, and an improved understanding of patient-specific challenges. Furthermore, digital technology has shown the potential to assist with patient rehabilitation.
在英国,每年进行的全髋关节置换术(THA)超过10万例。这一数字在全球范围内继续上升。结果仍然很好,然而,问题包括种植体错位,慢性疼痛和高达12%的不满意。成功的全髋关节置换术需要准确的植入物,以确保最佳的生物力学恢复。这篇综述评估了未来的潜在策略,这些策略将帮助外科医生通过使用机器人技术、数字技术和对患者特定挑战的更好理解来实现这些目标。此外,数字技术已经显示出协助患者康复的潜力。
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引用次数: 0
Management of painful metal-on-metal hip replacement: current evidence of diagnosis and treatment 疼痛金属对金属髋关节置换术的处理:目前的诊断和治疗证据
Q4 Medicine Pub Date : 2025-12-26 DOI: 10.1016/j.mporth.2025.11.002
Francesco Mancuso, Vittorio Vacca, Paolo Di Benedetto, Araldo Causero, Hemant Pandit
The evolution of metal-on-metal (MoM) total hip replacement exemplifies the tension between biomaterial innovation and long-term patient safety, highlighting the critical role of robust post-market surveillance. First-generation MoM implants, introduced in the 1960s, were designed to mitigate polyethylene wear but exhibited inconsistent fixation, variable tribological properties, and poorly characterized local tissue reactions, ultimately resulting in their decline. A resurgence of interest in the 1990s, driven by advances in metallurgy and precision engineering, promoted large-diameter femoral heads to enhance stability and reduce dislocation risk, leading to widespread use, particularly among young and active patients. However, registry data and multicentre analyses soon revealed inferior survivorship compared with metal-on-polyethylene and ceramic alternatives, primarily due to adverse reactions to metal debris. These encompass a spectrum of local tissue responses – including pseudotumour formation, aseptic lymphocytic vasculitis–associated lesions, and soft-tissue necrosis – often complicating both diagnosis and surgical management. Although concerns regarding systemic cobalt and chromium toxicity have been raised, large-scale cohort studies have not demonstrated population-level risks, underscoring the importance of individualized monitoring. Current diagnostic algorithms integrate clinical evaluation, serum ion measurements, and cross-sectional imaging such as metal artifact reduction sequence magnetic resonance imaging (MARS MRI), while surgical management emphasizes comprehensive debridement and revision to biologically favorable bearings, notably ceramic-on-highly cross-linked polyethylene. The decline of MoM implants has reshaped contemporary replacement practice by reinforcing preclinical testing standards, international registry collaboration, and vigilance in the clinical adoption of novel biomaterials.
金属对金属(MoM)全髋关节置换术的发展体现了生物材料创新与长期患者安全之间的紧张关系,突出了强有力的上市后监测的关键作用。第一代MoM植入物是在20世纪60年代推出的,旨在减轻聚乙烯的磨损,但其固定不一致,摩擦学性能不稳定,局部组织反应特征不佳,最终导致其衰退。20世纪90年代,在冶金和精密工程进步的推动下,人们对大直径股骨头的兴趣重新抬头,以增强稳定性和减少脱位风险,导致广泛使用,特别是在年轻和活跃的患者中。然而,注册数据和多中心分析很快显示,与金属对聚乙烯和陶瓷替代品相比,生存率较低,主要是由于金属碎片的不良反应。这些包括一系列局部组织反应,包括假性肿瘤形成、无菌淋巴细胞血管炎相关病变和软组织坏死,通常使诊断和手术治疗复杂化。尽管对系统性钴和铬毒性的担忧已经提出,但大规模队列研究尚未证明人群水平的风险,强调了个体化监测的重要性。目前的诊断算法整合了临床评估、血清离子测量和横断面成像,如金属伪影还原序列磁共振成像(MARS MRI),而手术管理则强调全面清创和修复生物学上有利的轴承,特别是陶瓷-高交联聚乙烯。MoM植入物的减少通过加强临床前测试标准、国际注册合作和临床采用新型生物材料的警惕,重塑了当代的替代实践。
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引用次数: 0
Techniques for femoral stem removal in revision hip arthroplasty 改良髋关节置换术中股骨干去除技术
Q4 Medicine Pub Date : 2025-12-26 DOI: 10.1016/j.mporth.2025.11.001
David Alan Skipsey, Matthew David Smith
The removal of the femoral stem is one of the challenging scenarios that the revision hip surgeon may face. There have been significant increases in the number of primary hip replacements being undertaken. Therefore it is likely this will result in an increase in need for revision, particularly where the stem may be well fixed such as in infection, instability or fracture. Safe removal of the stem without further damage to the bone by fracture or perforation is important to facilitate subsequent reconstruction. This article aims to cover the indications for stem extraction, challenges faced, alternatives to stem removal, importance of preoperative planning, exposure and techniques in removal of cemented and uncemented stems. This includes practical descriptions, tips/tricks and diagrams for undertaking the cortical window, trochanteric slide, posterior split and extended trochanteric osteotomy as well as discussion on recent technological advances.
股骨干的切除是髋关节翻修外科医生可能面临的挑战之一。正在进行的初级髋关节置换术的数量显著增加。因此,这可能会导致翻修需求的增加,特别是在感染、不稳定或骨折等可能固定良好的情况下。安全取出骨柄,避免骨折或穿孔对骨造成进一步损伤,这对后续重建非常重要。本文的目的是涵盖茎拔出的适应症,面临的挑战,茎拔出的替代方法,术前计划的重要性,骨水泥和非骨水泥茎拔出的暴露和技术。这包括进行皮质窗、粗隆滑动、后裂和扩大粗隆截骨术的实用描述、技巧和图表,以及对最新技术进展的讨论。
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引用次数: 0
Total hip arthroplasty in the context of obesity 肥胖患者的全髋关节置换术
Q4 Medicine Pub Date : 2025-12-26 DOI: 10.1016/j.mporth.2025.11.005
Conor J McCann, Scott R Morrison, Andrew J Hall, Edward Dunstan
Obesity is a rising global epidemic with significant implications for the development and progression of hip osteoarthritis (OA) and the subsequent need for total hip arthroplasty (THA). It is the most important modifiable risk factor for patients with hip OA undergoing THA and influences perioperative risk profiles as well as both short- and long-term outcomes. Although they have worse risk profiles, patients with obesity can achieve excellent outcomes when appropriately optimized. Preoperative weight reduction, metabolic control, and multidisciplinary optimization, including nutritional and psychological support, can reduce complications and enhance recovery. Surgical planning and intraoperative techniques remain critical to mitigate elevated surgical risk. The risk conferred by obesity in THA is graded, not binary. Increasingly, data appear to support surgical candidacy based on comprehensive risk management rather than categorical exclusion. Priorities for future research include developing more refined multivariable risk models, evaluation of integrated optimization pathways (including novel weight-loss strategies such as glucagon-like peptide-1 (GLP-1) receptor agonists), and high-quality economic studies incorporating long-term and societal costs. As global obesity prevalence rises, the demand for THA will continue to grow. Understanding these risks and implementing evidence-based optimization strategies will be vital for sustaining safe and equitable arthroplasty care worldwide.
肥胖是一种不断上升的全球流行病,对髋关节骨关节炎(OA)的发生和进展以及随后对全髋关节置换术(THA)的需求具有重要意义。它是髋关节OA患者行THA手术最重要的可改变的危险因素,影响围手术期风险概况以及短期和长期预后。虽然他们有更差的风险概况,肥胖患者可以达到良好的结果,适当优化。术前减重、控制代谢和多学科优化,包括营养和心理支持,可以减少并发症,促进康复。手术计划和术中技术仍然是降低手术风险的关键。THA中肥胖带来的风险是分级的,而不是二元的。越来越多的数据似乎支持基于全面风险管理而不是绝对排除的手术候选性。未来研究的重点包括开发更精细的多变量风险模型,评估综合优化途径(包括新的减肥策略,如胰高血糖素样肽-1 (GLP-1)受体激动剂),以及考虑长期和社会成本的高质量经济研究。随着全球肥胖患病率的上升,对全髋关节置换术的需求将继续增长。了解这些风险并实施循证优化策略对于在全球范围内维持安全和公平的关节置换术治疗至关重要。
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引用次数: 0
Acetabular bone loss in primary and revision arthroplasty: diagnosis, imaging, classification and management 初次和翻修关节置换术中髋臼骨丢失:诊断、影像学、分类和处理
Q4 Medicine Pub Date : 2025-12-26 DOI: 10.1016/j.mporth.2025.11.006
Samuel Metheringham, Samuel MacKenzie, Harry Sargeant
The number of total hip arthroplasties being performed every year is increasing. With the average age of these patients decreasing, combined with average life expectancy increasing, the future revision hip workload is set to increase. A rare but important factor associated with implant failure and subsequent revision surgery is acetabular bone loss. Bony defects of the acetabulum can pose a challenge in diagnosis, imaging, classification and management. In this review, we discuss the relevant anatomy of the hip and pelvis, the preoperative work-up and imaging patients undergo, the various classification systems that exist and how those systems guide management. Treatment options include hemispherical acetabular cups, cup-cage constructs, reconstructive rings and cages, bone impaction grafting allografts, metal augments and patient specific implants.
全髋关节置换术的数量每年都在增加。随着这些患者平均年龄的下降,加上平均预期寿命的增加,未来髋关节翻修工作量将会增加。髋臼骨丢失是导致假体失败和后续翻修手术的一个罕见但重要的因素。髋臼骨缺损在诊断、影像学、分类和治疗方面具有挑战性。在这篇综述中,我们讨论了髋关节和骨盆的相关解剖,术前检查和患者接受的影像学检查,现有的各种分类系统以及这些系统如何指导管理。治疗选择包括半球形髋臼杯、杯笼结构物、重建环和笼、同种异体骨嵌塞移植、金属增强物和患者特定植入物。
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引用次数: 0
Total hip replacement in patients under 30 years of age: challenges, outcomes and future directions 30岁以下患者的全髋关节置换术:挑战、结果和未来方向
Q4 Medicine Pub Date : 2025-12-26 DOI: 10.1016/j.mporth.2025.11.007
Abdelwakeel Bakhiet, James Dixon, Mostafa Beshr, Michael Reidy
Total hip replacement (THR) in patients under 30 years of age remains a complex and evolving area of orthopaedic practice, with surgeons historically withholding from performing THR in this cohort due to high rates of aseptic loosening and revision. However, advances in implant design, bearing surfaces, and surgical techniques have facilitated a shift towards an increase in THR procedures in younger patients. This review synthesises the contemporary evidence surrounding indications, surgical challenges, implant selection and outcomes in this population. Pathologies such as juvenile idiopathic arthritis, developmental dysplasia of the hip and avascular necrosis present unique anatomical and biomechanical considerations necessitating meticulous preoperative planning and tailored intraoperative strategies. Cementless fixation techniques and contemporary bearing materials have significantly improved implant survivorship and reduced polyethylene wear. Despite these innovations, younger patients continue to exhibit higher revision rates relative to older cohorts due to increased functional demands and longer life expectancy. Patient-reported outcome measures demonstrate substantial postoperative improvements in pain and mobility, which are pivotal during these years of cognitive and emotional development. However, expectations and preoperative status remain a critical determinant of satisfaction. Optimizing outcomes requires a nuanced approach balancing functional restoration, preservation of bone stock for future revisions and careful management of patient expectations. Prospective long-term studies are essential to refine strategies in this challenging demographic.
30岁以下患者的全髋关节置换术(THR)仍然是骨科实践中一个复杂且不断发展的领域,由于无菌性松动和翻修率高,外科医生历来不愿在这一人群中进行THR。然而,种植体设计、承载表面和手术技术的进步促进了年轻患者THR手术的增加。这篇综述综合了这一人群的适应症、手术挑战、种植体选择和结果的当代证据。青少年特发性关节炎、发育性髋关节发育不良和缺血性坏死等病理表现出独特的解剖学和生物力学方面的考虑,需要细致的术前计划和量身定制的术中策略。无骨水泥固定技术和现代轴承材料显著改善了种植体的存活并减少了聚乙烯磨损。尽管有这些创新,由于功能需求的增加和预期寿命的延长,相对于老年患者,年轻患者继续表现出更高的翻修率。患者报告的结果显示,术后疼痛和活动能力有了实质性的改善,这在这些年的认知和情感发展中是至关重要的。然而,期望和术前状态仍然是满意度的关键决定因素。优化结果需要一种细致入微的方法来平衡功能恢复、保留骨储备以备将来的修订和仔细管理患者的期望。前瞻性长期研究对于完善这一具有挑战性的人口统计策略至关重要。
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引用次数: 0
CME questions on Hip Arthroplasty 关于髋关节置换术的CME问题
Q4 Medicine Pub Date : 2025-12-23 DOI: 10.1016/j.mporth.2025.11.009
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引用次数: 0
Answers to the CME questions on Spinal Deformity and Other Spinal Conditions 解答CME关于脊柱畸形和其他脊柱疾病的问题
Q4 Medicine Pub Date : 2025-12-23 DOI: 10.1016/j.mporth.2025.11.008
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引用次数: 0
The treatment options for patients with an adolescent idiopathic scoliosis 青少年特发性脊柱侧凸患者的治疗选择
Q4 Medicine Pub Date : 2025-12-01 DOI: 10.1016/j.mporth.2025.09.005
Zaki B Choudhury, Athanasios I Tsirikos
Adolescent idiopathic scoliosis is a relatively common condition, being observed in 2–3% of 10–18 year olds-a key period of a patient's life in terms of physical, social and emotional development. Of this group 10% may require intervention, with approximately 10% of this subgroup requiring surgical intervention. We discuss definitions and a scheme for management of scoliosis in this particular population. Treatment options are described relative to the degree of curvature, rate of progression and patient psychosocial and cosmetic aspects, with an overview of outcomes. Elements of bracing and advances are reviewed and an introduction into surgical correction approaches, techniques and implants outlined.
青少年特发性脊柱侧凸是一种相对常见的疾病,在10-18岁的青少年中有2-3%的人被观察到,这是患者一生中身体、社会和情感发展的关键时期。在这一组中,10%的患者可能需要干预,其中约10%的患者需要手术干预。我们讨论定义和管理方案的脊柱侧凸在这一特定人群。治疗方案描述相对于曲率的程度,进展率和患者心理社会和美容方面,与结果的概述。回顾了支具的元素和进展,并介绍了手术矫正方法,技术和植入物概述。
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引用次数: 0
期刊
Orthopaedics and Trauma
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