首页 > 最新文献

Tanzania Journal of Health Research最新文献

英文 中文
Postpartum glycemia and pregnancy outcomes among women in Arusha Region, Tanzania 坦桑尼亚阿鲁沙地区妇女产后血糖和妊娠结局
Q4 Medicine Pub Date : 2022-09-27 DOI: 10.4314/thrb.v23i4.9
S. S. Msollo, A. Mwanri
Background: Gestational diabetes mellitus is a medical condition that disappears after delivery if early diagnosis and management are done. This study aimed to determine the prevalence of hyperglycemia six weeks postpartum and pregnancy outcomes among women in Arusha City.   Methods: A longitudinal study was conducted between March and December 2018 as part of a large study which involved 468 randomly selected pregnant women and excluded those who were diagnosed with diabetes before pregnancy. Women were screened for hyperglycemia six weeks postpartum where fasting and oral glucose tolerant tests were done by Gluco-Plus™ using World Health Organization criteria. Body fat percentage, mid-upper arm circumference, height and weight were measured using standard procedures. Postpartum information was collected using a structured questionnaire and data was analyzed using the Statistical Package for Social Science version 20 to obtain descriptive and inferential statistics. Results: Among 468 women who participated in the study at baseline, 392 (83.7%) returned for postpartum assessments. Postpartum hyperglycemia among women was 2.1% (n=8) and majority had normal delivery (92.6%, n=363) while 7.4% (n=29) delivered through caesarean section. About 8.2% (n=32) of the newborn were macrosomia and 4.1% (n=16) low birth weight. Miscarriages or abortions were not identified while stillbirth was observed in 0.5% (n=2) and neonatal death (1.3%, n=5). Postpartum hyperglycemia was significantly associated with body fat percentage (AOR 1.59, 95% CI: 1.14-1.91), mid-upper arm circumference (AOR 1.62, 95% CI: 1.023-1.99), macrosomia (AOR 2.43, 95% CI: 2.2-10.31) and family history of type 2 diabetes (AOR 6.4, 95% CI: 1.93-13.3). Conclusion: Prevalence of postpartum hyperglycemia was generally low however; it was significantly associated with macrosomia, increased body fat percentage, mid-upper circumference and family history of type 2 diabetes.  Also, a low prevalence of poor pregnancy outcomes was reported which may be attributed to actions taken after being referred for further treatments and management which need further exploration.  
背景:妊娠期糖尿病是一种如果早期诊断和治疗,在分娩后就会消失的疾病。本研究旨在确定阿鲁沙市妇女产后六周高血糖的患病率和妊娠结局。方法:作为一项大型研究的一部分,在2018年3月至12月期间进行了一项纵向研究,该研究涉及468名随机选择的孕妇,并排除了那些在怀孕前被诊断为糖尿病的孕妇。女性产后六周进行高血糖筛查,通过Gluco Plus进行禁食和口服葡萄糖耐量测试™ 使用世界卫生组织的标准。使用标准程序测量体脂百分比、上臂中围、身高和体重。使用结构化问卷收集产后信息,并使用社会科学统计包第20版对数据进行分析,以获得描述性和推断性统计数据。结果:在468名基线参与研究的女性中,392人(83.7%)返回进行产后评估。产后高血糖女性为2.1%(n=8),大多数正常分娩(92.6%,n=363),而7.4%(n=29)通过剖腹产分娩。新生儿中约8.2%(n=32)为巨大儿,4.1%(n=16)为低出生体重儿。未发现流产或流产,但观察到0.5%(n=2)的死产和1.3%(n=5)的新生儿死亡。产后高血糖与体脂率(AOR 1.59,95%CI:1.14-1.91)、中上臂围(AOR 1.62,95%CI:1.023-1.99)、巨大儿(AOR 2.43,95%CI:2.2-10.31)和2型糖尿病家族史(AOR 6.4,95%CI:1.93-13.3)显著相关;它与巨大儿、体脂百分比增加、中上围和2型糖尿病家族史显著相关。此外,据报道,不良妊娠结局的发生率较低,这可能归因于在转诊接受进一步治疗和管理后采取的行动,需要进一步探索。
{"title":"Postpartum glycemia and pregnancy outcomes among women in Arusha Region, Tanzania","authors":"S. S. Msollo, A. Mwanri","doi":"10.4314/thrb.v23i4.9","DOIUrl":"https://doi.org/10.4314/thrb.v23i4.9","url":null,"abstract":"Background: Gestational diabetes mellitus is a medical condition that disappears after delivery if early diagnosis and management are done. This study aimed to determine the prevalence of hyperglycemia six weeks postpartum and pregnancy outcomes among women in Arusha City.   \u0000Methods: A longitudinal study was conducted between March and December 2018 as part of a large study which involved 468 randomly selected pregnant women and excluded those who were diagnosed with diabetes before pregnancy. Women were screened for hyperglycemia six weeks postpartum where fasting and oral glucose tolerant tests were done by Gluco-Plus™ using World Health Organization criteria. Body fat percentage, mid-upper arm circumference, height and weight were measured using standard procedures. Postpartum information was collected using a structured questionnaire and data was analyzed using the Statistical Package for Social Science version 20 to obtain descriptive and inferential statistics. \u0000Results: Among 468 women who participated in the study at baseline, 392 (83.7%) returned for postpartum assessments. Postpartum hyperglycemia among women was 2.1% (n=8) and majority had normal delivery (92.6%, n=363) while 7.4% (n=29) delivered through caesarean section. About 8.2% (n=32) of the newborn were macrosomia and 4.1% (n=16) low birth weight. Miscarriages or abortions were not identified while stillbirth was observed in 0.5% (n=2) and neonatal death (1.3%, n=5). Postpartum hyperglycemia was significantly associated with body fat percentage (AOR 1.59, 95% CI: 1.14-1.91), mid-upper arm circumference (AOR 1.62, 95% CI: 1.023-1.99), macrosomia (AOR 2.43, 95% CI: 2.2-10.31) and family history of type 2 diabetes (AOR 6.4, 95% CI: 1.93-13.3). \u0000Conclusion: Prevalence of postpartum hyperglycemia was generally low however; it was significantly associated with macrosomia, increased body fat percentage, mid-upper circumference and family history of type 2 diabetes.  Also, a low prevalence of poor pregnancy outcomes was reported which may be attributed to actions taken after being referred for further treatments and management which need further exploration.  ","PeriodicalId":39815,"journal":{"name":"Tanzania Journal of Health Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41658092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Contraceptive practices among women of reproductive age in Mbeya, Tanzania 坦桑尼亚姆贝亚育龄妇女的避孕措施
Q4 Medicine Pub Date : 2022-09-27 DOI: 10.4314/thrb.v23i4.1
Yina Hamis, Elias Kaminyoghe, C. Mweya
Background: Non-utilisation of contraceptive contribute to unintended pregnancies and unsafe abortions, which are major public health problems in Tanzania and sub-Saharan Africa. Our study investigated contributing factors and contraceptive use practices among women of reproductive age in Mbeya, Tanzania. Methods: A hospital-based descriptive cross-sectional study was conducted on women attending reproductive and child health clinics. Data obtained included participants’ age, education and other demographic characteristics. Awareness of family planning methods, use, attitudes, advocacy and practices were also recorded. A χ2 test was used to examine the association between selected variables.  Results: A total of 217 respondents participated in the study, of which the majority were between the ages of 21 and 26 (mean age = 26.96, standard deviation = 1.37). The majority of the respondents, 157 (72.4%) were married with mostly 1-2 children and had a primary school education or without formal education, 155 (71.4%).  191 (88.0%) respondents had heard about at least one contraceptive for family planning. Injectable was the most known method of family planning, as reported by 158 (72.8%) participants. Awareness about family planning methods and use was significantly associated with educational level (χ2 = 43.01, p = 0.0002). Conclusion: Our study shows awareness and willingness to use family planning methods in Mbeya. Hence, it promotes a better life for families. However, more studies are needed to thoroughly investigate the various reasons affecting some non-utilisation of family planning and how these can be addressed.
背景:未使用避孕药具导致意外怀孕和不安全堕胎,这是坦桑尼亚和撒哈拉以南非洲的主要公共卫生问题。我们的研究调查了坦桑尼亚姆贝亚育龄妇女的影响因素和避孕方法。方法:对在生殖和儿童健康诊所就诊的妇女进行了一项基于医院的描述性横断面研究。获得的数据包括参与者的年龄、教育程度和其他人口特征。还记录了对计划生育方法、用途、态度、宣传和做法的认识。χ2检验用于检验所选变量之间的相关性。结果:共有217名受访者参与了这项研究,其中大多数受访者年龄在21至26岁之间(平均年龄=26.96,标准差=1.37)。大多数受访者157人(72.4%)已婚,大多有1-2个孩子,受过小学教育或没有受过正规教育,155名(71.4%)。191名(88.0%)受访者听说过至少一种计划生育避孕药。据158名(72.8%)参与者报告,注射是最为人所知的计划生育方法。对计划生育方法和使用的认识与教育水平显著相关(χ2=43.01,p=0.0002)。因此,它促进了家庭更好的生活。然而,还需要更多的研究来彻底调查影响一些不使用计划生育的各种原因,以及如何解决这些问题。
{"title":"Contraceptive practices among women of reproductive age in Mbeya, Tanzania","authors":"Yina Hamis, Elias Kaminyoghe, C. Mweya","doi":"10.4314/thrb.v23i4.1","DOIUrl":"https://doi.org/10.4314/thrb.v23i4.1","url":null,"abstract":"Background: Non-utilisation of contraceptive contribute to unintended pregnancies and unsafe abortions, which are major public health problems in Tanzania and sub-Saharan Africa. Our study investigated contributing factors and contraceptive use practices among women of reproductive age in Mbeya, Tanzania. \u0000Methods: A hospital-based descriptive cross-sectional study was conducted on women attending reproductive and child health clinics. Data obtained included participants’ age, education and other demographic characteristics. Awareness of family planning methods, use, attitudes, advocacy and practices were also recorded. A χ2 test was used to examine the association between selected variables.  \u0000Results: A total of 217 respondents participated in the study, of which the majority were between the ages of 21 and 26 (mean age = 26.96, standard deviation = 1.37). The majority of the respondents, 157 (72.4%) were married with mostly 1-2 children and had a primary school education or without formal education, 155 (71.4%).  191 (88.0%) respondents had heard about at least one contraceptive for family planning. Injectable was the most known method of family planning, as reported by 158 (72.8%) participants. Awareness about family planning methods and use was significantly associated with educational level (χ2 = 43.01, p = 0.0002). \u0000Conclusion: Our study shows awareness and willingness to use family planning methods in Mbeya. Hence, it promotes a better life for families. However, more studies are needed to thoroughly investigate the various reasons affecting some non-utilisation of family planning and how these can be addressed.","PeriodicalId":39815,"journal":{"name":"Tanzania Journal of Health Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48948610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
HIV seroprevalence, clinical profile and surgical outcomes among patients with acquired anorectal conditions in two referral hospitals in Mwanza, Tanzania 坦桑尼亚姆万扎两所转诊医院获得性肛肠疾病患者的HIV血清流行率、临床特征和手术结果
Q4 Medicine Pub Date : 2022-09-27 DOI: 10.4314/thrb.v23i4.3
Dino Mwaja, Leonard Washington, Tresphory Boniface, J. Seni, M. Mirambo, W. Mahalu, O. Kituuka, P. Chalya
Background: HIV infection, a major health problem worldwide, has been reported to be prevalent in patients with acquired anorectal conditions. There is a paucity of prospective studies regarding acquired anorectal conditions in Tanzania. This study describes the HIV seroprevalence, clinical profile and surgical outcomes among patients with acquired anorectal conditions at Bugando Medical Centre (BMC) and Sekou-Toure Referral Regional Hospital (SRRH). Methods: This was a cross-sectional study that was conducted among patients with acquired anorectal conditions as seen at BMC and SRRH from January 2019 to June 2019. Results:  A total of 389 patients (M: F ratio = 1.5:1) were studied. The median age at diagnosis was 42 years. Out of 389 patients, 101(26.0%) were HIV positive. Of these, 54(53.5%) were males and 47 (46.5%) were females. Haemorrhoids were the most common acquired anorectal disease accounting for 50.9% of cases. The rate of HIV infection in this study was significantly high in patients with hemorrhoids (p< 0.001), perianal ulcers (p< 0.001), anorectal abscess (p = 0.009), perianal warts (p< 0.001) and rectal prolapse (p = 0.023). A total of 173 (44.5%) patients underwent surgical treatment for acquired anorectal conditions. Hemorrhoidectomy was the most commonly performed surgical procedure in 95(54.9%) patients. Out of 171 patients who underwent surgical treatment and outcomes evaluated, 138 were treated successfully giving an overall success rate of 80.7%.  The success rate was significantly influenced by HIV positivity (p = 0.002). Surgical site infection (SSI) was the most common postoperative complication accounting for 25.8% of cases. The rate of SSI was found to be significantly higher in HIV-positive patients than in HIV-negative patients (39.6% vs 18.5%; p-value = 0.001). Conclusion: HIV infection is prevalent among patients with acquired anorectal conditions in our setting and influences surgical outcomes. We recommend that all patients with acquired anorectal conditions in this region should be screened for HIV infection.
背景:艾滋病毒感染是世界范围内的一个主要健康问题,据报道在获得性肛肠疾病患者中普遍存在。坦桑尼亚缺乏关于获得性肛肠疾病的前瞻性研究。本研究描述了Bugando医疗中心(BMC)和Sekou-Toure转诊地区医院(SRRH)获得性肛肠疾病患者的艾滋病毒血清感染率、临床概况和手术结果。方法:这是一项横断面研究,在2019年1月至2019年6月在BMC和SRRH看到的获得性肛肠疾病患者中进行。结果:共纳入389例患者(M: F = 1.5:1)。诊断时的中位年龄为42岁。在389例患者中,101例(26.0%)为HIV阳性。其中男性54例(53.5%),女性47例(46.5%)。痔疮是最常见的获得性肛肠疾病,占50.9%。本研究中HIV感染率在痔疮(p< 0.001)、肛周溃疡(p< 0.001)、肛管直肠脓肿(p = 0.009)、肛周疣(p< 0.001)和直肠脱垂(p = 0.023)患者中显著较高。173例(44.5%)患者接受了获得性肛肠疾病的手术治疗。在95例(54.9%)患者中,痔疮切除术是最常见的外科手术。在171例接受手术治疗和结果评估的患者中,138例治疗成功,总成功率为80.7%。HIV阳性对成功率有显著影响(p = 0.002)。手术部位感染(SSI)是最常见的术后并发症,占25.8%。hiv阳性患者的SSI发生率明显高于hiv阴性患者(39.6% vs 18.5%;p值= 0.001)。结论:HIV感染在获得性肛肠疾病患者中普遍存在,并影响手术结果。我们建议该地区所有获得性肛肠疾病患者都应进行HIV感染筛查。
{"title":"HIV seroprevalence, clinical profile and surgical outcomes among patients with acquired anorectal conditions in two referral hospitals in Mwanza, Tanzania","authors":"Dino Mwaja, Leonard Washington, Tresphory Boniface, J. Seni, M. Mirambo, W. Mahalu, O. Kituuka, P. Chalya","doi":"10.4314/thrb.v23i4.3","DOIUrl":"https://doi.org/10.4314/thrb.v23i4.3","url":null,"abstract":"Background: HIV infection, a major health problem worldwide, has been reported to be prevalent in patients with acquired anorectal conditions. There is a paucity of prospective studies regarding acquired anorectal conditions in Tanzania. This study describes the HIV seroprevalence, clinical profile and surgical outcomes among patients with acquired anorectal conditions at Bugando Medical Centre (BMC) and Sekou-Toure Referral Regional Hospital (SRRH). \u0000Methods: This was a cross-sectional study that was conducted among patients with acquired anorectal conditions as seen at BMC and SRRH from January 2019 to June 2019. \u0000Results:  A total of 389 patients (M: F ratio = 1.5:1) were studied. The median age at diagnosis was 42 years. Out of 389 patients, 101(26.0%) were HIV positive. Of these, 54(53.5%) were males and 47 (46.5%) were females. Haemorrhoids were the most common acquired anorectal disease accounting for 50.9% of cases. The rate of HIV infection in this study was significantly high in patients with hemorrhoids (p< 0.001), perianal ulcers (p< 0.001), anorectal abscess (p = 0.009), perianal warts (p< 0.001) and rectal prolapse (p = 0.023). A total of 173 (44.5%) patients underwent surgical treatment for acquired anorectal conditions. Hemorrhoidectomy was the most commonly performed surgical procedure in 95(54.9%) patients. Out of 171 patients who underwent surgical treatment and outcomes evaluated, 138 were treated successfully giving an overall success rate of 80.7%.  The success rate was significantly influenced by HIV positivity (p = 0.002). Surgical site infection (SSI) was the most common postoperative complication accounting for 25.8% of cases. The rate of SSI was found to be significantly higher in HIV-positive patients than in HIV-negative patients (39.6% vs 18.5%; p-value = 0.001). \u0000Conclusion: HIV infection is prevalent among patients with acquired anorectal conditions in our setting and influences surgical outcomes. We recommend that all patients with acquired anorectal conditions in this region should be screened for HIV infection.","PeriodicalId":39815,"journal":{"name":"Tanzania Journal of Health Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45491747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence and factors associated with undernutrition among under-five children in Gairo district in Morogoro, Tanzania 坦桑尼亚莫罗戈罗盖罗区五岁以下儿童营养不良的患病率和相关因素
Q4 Medicine Pub Date : 2022-09-27 DOI: 10.4314/thrb.v23i4.8
Tausi Mtonga, C. Nyaruhucha
Background: In Tanzania, under-nutrition is of most public concern as it affects human productivity in several areas like increasing economic costs to families and the country as a whole and impairing learning. Therefore this study aimed at assessing the prevalence and factors associated with undernutrition among under-five children in Gairo district, Morogoro. Findings from the study will help policymakers, and local and international organizations in designing appropriate nutrition policies and interventions to address undernutrition in rural areas. Methods: A household-based cross-sectional study was employed involving 300 under-five children with their mothers/caretakers in three wards in Gairo district. A structured questionnaire was used and anthropometric measurements were performed using standard procedures. Odds ratio with a 95% confidence interval and p-value at <=0.05 was used to identify factors associated with undernutrition. Results: The study revealed that the prevalence of stunting was 54.3% (severe stunting 26.3% and moderate stunting 28%), underweight 23.3% (severe underweight 7% and moderate underweight 16.3%) and wasting 3.7% (severe wasting 1.3% and moderate wasting 2.4%). Conclusion: The main factors that showed positive association were being a male, maternal occupation, child’s age, maternal education, birth weight, and illness in the past one month, area of residence, maternal age, and time of introduction of solid foods and leaving a child when being outside. The prevalence of stunting and underweight in the study area was higher compared to the national and regional prevalence. Thus due attention is needed while much attention should be given to the factors that showed a positive association.
背景:在坦桑尼亚,营养不足是最受公众关注的问题,因为它影响了几个领域的人类生产力,比如增加家庭和整个国家的经济成本,损害学习。因此,本研究旨在评估莫罗戈罗盖罗区五岁以下儿童营养不良的患病率和相关因素。研究结果将有助于决策者、地方和国际组织制定适当的营养政策和干预措施,以解决农村地区的营养不良问题。方法:采用一项基于家庭的横断面研究,涉及盖罗区三个病房的300名五岁以下儿童及其母亲/看护人。使用结构化问卷,并使用标准程序进行人体测量。使用95%置信区间和p值<=0.05的比值比来确定与营养不良相关的因素。结果:研究显示,发育迟缓的患病率为54.3%(严重发育迟缓26.3%和中度发育迟缓28%)、体重不足23.3%(严重体重不足7%和中度体重不足16.3%)和消瘦3.7%(严重消瘦1.3%和中度消瘦2.4%),出生体重、过去一个月的疾病、居住地区、产妇年龄、摄入固体食物和外出时留下孩子的时间。研究地区发育迟缓和体重不足的患病率高于全国和地区的患病率。因此,需要给予应有的关注,同时应多注意显示出积极关联的因素。
{"title":"Prevalence and factors associated with undernutrition among under-five children in Gairo district in Morogoro, Tanzania","authors":"Tausi Mtonga, C. Nyaruhucha","doi":"10.4314/thrb.v23i4.8","DOIUrl":"https://doi.org/10.4314/thrb.v23i4.8","url":null,"abstract":"Background: In Tanzania, under-nutrition is of most public concern as it affects human productivity in several areas like increasing economic costs to families and the country as a whole and impairing learning. Therefore this study aimed at assessing the prevalence and factors associated with undernutrition among under-five children in Gairo district, Morogoro. Findings from the study will help policymakers, and local and international organizations in designing appropriate nutrition policies and interventions to address undernutrition in rural areas. \u0000Methods: A household-based cross-sectional study was employed involving 300 under-five children with their mothers/caretakers in three wards in Gairo district. A structured questionnaire was used and anthropometric measurements were performed using standard procedures. Odds ratio with a 95% confidence interval and p-value at <=0.05 was used to identify factors associated with undernutrition. \u0000Results: The study revealed that the prevalence of stunting was 54.3% (severe stunting 26.3% and moderate stunting 28%), underweight 23.3% (severe underweight 7% and moderate underweight 16.3%) and wasting 3.7% (severe wasting 1.3% and moderate wasting 2.4%). \u0000Conclusion: The main factors that showed positive association were being a male, maternal occupation, child’s age, maternal education, birth weight, and illness in the past one month, area of residence, maternal age, and time of introduction of solid foods and leaving a child when being outside. The prevalence of stunting and underweight in the study area was higher compared to the national and regional prevalence. Thus due attention is needed while much attention should be given to the factors that showed a positive association.","PeriodicalId":39815,"journal":{"name":"Tanzania Journal of Health Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49176852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Admission hyperglycaemia as a prognostic indicator of outcome in major trauma patients at Bugando Medical Centre, Mwanza, Tanzania 坦桑尼亚姆万扎布甘多医疗中心重大创伤患者入院时高血糖作为预后指标
Q4 Medicine Pub Date : 2022-09-27 DOI: 10.4314/thrb.v23i4.6
Angelo Njau, Leonard Washington, I. Akaro, B. Kidenya, O. Kituuka, P. Chalya
Background: Admission hyperglycemia has been reported to be associated with poor outcomes among patients with major trauma. However, most of the available literature on this subject has been conducted in the developed world. This study aimed to determine the association between admission hyperglycemia and the outcome of major trauma patients admitted to Bugando Medical Centre. Methods: This was a prospective cohort study, involving major trauma patients admitted to Bugando Medical Centre (BMC) within 6 months from Sept 2017 to February 2018. The exposure was admission hyperglycemia (>11.1mmol/l) and non-exposure was normoglycemia (≤11.1mmol/l). Results:  A total of 217 patients (M: F ratio = 4.1: 1) were recruited. Their ages ranged from 4 to 97 years with a median age of 31 years. Out of 217 patients, 106 (48.8%) were hyperglycemic and the remaining 111(51.2%) were normoglycemic. The overall median days of length of hospital stay (LOS) was 15 days. There was no statistically significant association between admission hyperglycemia and LOS (p =0.875). In this study, 73 patients died giving a mortality of 33.6%. Patients with admission hyperglycemia (>11.1mmol/l) had significantly higher mortality as compared to normoglycemic patients (≤11.1mmol/l) (p < 0.001). Conclusion: This study found that admission hyperglycemia was statistically significantly associated with increased mortality among major trauma patients at BMC. Therefore, there is a need to institute regular monitoring of blood sugar levels among these patients and give appropriate treatment to those found with elevated blood sugar levels.
背景:据报道,入院时高血糖与严重创伤患者的不良预后有关。然而,关于这一主题的大多数现有文献都是在发达国家进行的。本研究旨在确定入住布甘多医疗中心的严重创伤患者的入院高血糖与预后之间的关系。方法:这是一项前瞻性队列研究,涉及2017年9月至2018年2月6个月内入住布甘多医疗中心(BMC)的重大创伤患者。暴露为入院高血糖(>111.1mmol/l),非暴露为血糖正常(≤11.1mmol/l)。结果:共招募217名患者(M:F比=4.1:1)。他们的年龄从4岁到97岁不等,中位年龄为31岁。在217名患者中,106名(48.8%)血糖过高,其余111名(51.2%)血糖正常。住院总天数中位数为15天。入院高血糖与LOS之间无统计学显著相关性(p=0.875),73名患者死亡,死亡率为33.6%。入院时高血糖(>111.1mmol/l)患者的死亡率明显高于血糖正常(≤11.1mmol/l)患者(p<0.001)。因此,有必要定期监测这些患者的血糖水平,并对血糖水平升高的患者进行适当治疗。
{"title":"Admission hyperglycaemia as a prognostic indicator of outcome in major trauma patients at Bugando Medical Centre, Mwanza, Tanzania","authors":"Angelo Njau, Leonard Washington, I. Akaro, B. Kidenya, O. Kituuka, P. Chalya","doi":"10.4314/thrb.v23i4.6","DOIUrl":"https://doi.org/10.4314/thrb.v23i4.6","url":null,"abstract":"Background: Admission hyperglycemia has been reported to be associated with poor outcomes among patients with major trauma. However, most of the available literature on this subject has been conducted in the developed world. This study aimed to determine the association between admission hyperglycemia and the outcome of major trauma patients admitted to Bugando Medical Centre. \u0000Methods: This was a prospective cohort study, involving major trauma patients admitted to Bugando Medical Centre (BMC) within 6 months from Sept 2017 to February 2018. The exposure was admission hyperglycemia (>11.1mmol/l) and non-exposure was normoglycemia (≤11.1mmol/l). \u0000Results:  A total of 217 patients (M: F ratio = 4.1: 1) were recruited. Their ages ranged from 4 to 97 years with a median age of 31 years. Out of 217 patients, 106 (48.8%) were hyperglycemic and the remaining 111(51.2%) were normoglycemic. The overall median days of length of hospital stay (LOS) was 15 days. There was no statistically significant association between admission hyperglycemia and LOS (p =0.875). In this study, 73 patients died giving a mortality of 33.6%. Patients with admission hyperglycemia (>11.1mmol/l) had significantly higher mortality as compared to normoglycemic patients (≤11.1mmol/l) (p < 0.001). \u0000Conclusion: This study found that admission hyperglycemia was statistically significantly associated with increased mortality among major trauma patients at BMC. Therefore, there is a need to institute regular monitoring of blood sugar levels among these patients and give appropriate treatment to those found with elevated blood sugar levels.","PeriodicalId":39815,"journal":{"name":"Tanzania Journal of Health Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43335642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exogenous poisoning in Tocantins - Brazil: a retrospective study from 2017 to 2021 巴西托坎廷斯外源性中毒:2017年至2021年的回顾性研究
Q4 Medicine Pub Date : 2022-09-27 DOI: 10.4314/thrb.v23i4.10
D. G. Kramer, Amanda Pereira Ferreira
Exogenous intoxication occurs due to the interaction with some chemical substances that lead to the appearance of varied signs and symptoms, from topical exanthema to severe systemic complications, hemorrhages, shock, coma and death. Therefore, it is important to report cases to epidemiological surveillance for the implementation of practices and actions that lead to their prevention. Thus, the objective was to analyze the compulsory notifications for exogenous intoxication in the Brazilian Northeast from 2014 to 2017. For that, a descriptive, retrospective and quantitative study was developed from cases reported in the National System of Diseases and Notifications (SINAN) in the Northeast region of Brazil. A total of 101,845 cases of exogenous intoxication were reported, with a greater predominance among: women (52.74%); brown race/color (61.42%) and age group from 20 to 39 years (37.88%). The drug was the main cause of intoxication with 35,646 cases (34.99%). The suicide attempt stood out in the circumstances studied (24.54%). The acute clinical criterion was the most relevant with 54,836 cases and the most observed clinical course was cure without sequelae (65.61%). There were no records for the following variables: Ethnicity (27.90%); Education (20.33%); Toxic agent (19.10%); Clinical evolution (30.10%) and Circumstance (23.84%). Thus, it was possible to verify that exogenous intoxication is an investigation event of extreme relevance to public health. This fact suggests the need for preventive actions and health education for the population of the region.
外源性中毒是由于与一些化学物质相互作用而发生的,这些化学物质会导致各种体征和症状的出现,从局部皮疹到严重的全身并发症、出血、休克、昏迷和死亡。因此,重要的是向流行病学监测报告病例,以实施预防措施和行动。因此,目的是分析2014年至2017年巴西东北部外源性中毒的强制通知。为此,根据巴西东北地区国家疾病和通知系统(SINAN)报告的病例进行了一项描述性、回顾性和定量研究。共报告101845例外源性中毒病例,其中以女性为主(52.74%);棕色人种/肤色(61.42%)和20至39岁年龄组(37.88%)。药物是中毒的主要原因,有35646例(34.99%)。自杀未遂在所研究的情况下尤为突出(24.54%)。急性临床标准最相关,有54836例,最观察到的临床过程是治愈无后遗症(65.61%)变量:种族(27.90%);教育(20.33%);有毒剂(19.10%);临床演变(30.10%)和环境(23.84%)。因此,可以验证外源性中毒是一个与公共卫生极端相关的调查事件。这一事实表明,有必要对该地区的人口采取预防行动和进行健康教育。
{"title":"Exogenous poisoning in Tocantins - Brazil: a retrospective study from 2017 to 2021","authors":"D. G. Kramer, Amanda Pereira Ferreira","doi":"10.4314/thrb.v23i4.10","DOIUrl":"https://doi.org/10.4314/thrb.v23i4.10","url":null,"abstract":"Exogenous intoxication occurs due to the interaction with some chemical substances that lead to the appearance of varied signs and symptoms, from topical exanthema to severe systemic complications, hemorrhages, shock, coma and death. Therefore, it is important to report cases to epidemiological surveillance for the implementation of practices and actions that lead to their prevention. Thus, the objective was to analyze the compulsory notifications for exogenous intoxication in the Brazilian Northeast from 2014 to 2017. For that, a descriptive, retrospective and quantitative study was developed from cases reported in the National System of Diseases and Notifications (SINAN) in the Northeast region of Brazil. A total of 101,845 cases of exogenous intoxication were reported, with a greater predominance among: women (52.74%); brown race/color (61.42%) and age group from 20 to 39 years (37.88%). The drug was the main cause of intoxication with 35,646 cases (34.99%). The suicide attempt stood out in the circumstances studied (24.54%). The acute clinical criterion was the most relevant with 54,836 cases and the most observed clinical course was cure without sequelae (65.61%). There were no records for the following variables: Ethnicity (27.90%); Education (20.33%); Toxic agent (19.10%); Clinical evolution (30.10%) and Circumstance (23.84%). Thus, it was possible to verify that exogenous intoxication is an investigation event of extreme relevance to public health. This fact suggests the need for preventive actions and health education for the population of the region.","PeriodicalId":39815,"journal":{"name":"Tanzania Journal of Health Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45545291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sexual harassment in public transport among female university students in Dar es Salaam, Tanzania 坦桑尼亚达累斯萨拉姆女大学生公共交通中的性骚扰
Q4 Medicine Pub Date : 2022-09-27 DOI: 10.4314/thrb.v23i4.4
I. Mosha, Grace Mapunda, Christopher H Mbotwa, T. Nyamhanga
Background: Globally, women and girls are subjected to various forms of sexual harassment while using public transport daily. Objective: To determine the prevalence of sexual harassment and identify different forms and associated risk factors among female university students who use public transport in Dar es Salaam, Tanzania. Methods: A cross-sectional study design using a questionnaire was employed to collect data. Data were collected from female first-year undergraduate students, who use public transport and are aged 18 years and above studying at the University of Dar es Salaam and Muhimbili University of Health and Allied Sciences.      Results: The overall prevalence of sexual harassment on public transport was 88%. Study participants reported the highest levels of sexual harassment (91%). Verbal harassment was the most common form of sexual harassment (95%), and being called names such as baby, sweet, honey or love was reported by most students (78%). Factors associated with sexual harassment on public transport were: overcrowded vehicles (AOR=2.90, 95% CI: 0.09-4.50) and use of public transport as a form of transport (AOR=4.54, 95% CI: 0.40-8.90).  Conclusion: The study findings highlight the need for the implementation of plausible interventions on the issue of sexual harassment through awareness campaigns and the implementation of modern surveillance and reporting systems in public spaces.
背景:在全球范围内,妇女和女孩每天在使用公共交通工具时遭受各种形式的性骚扰。目的:确定坦桑尼亚达累斯萨拉姆女大学生乘坐公共交通工具的性骚扰发生率,并确定不同形式和相关风险因素。方法:采用横断面研究设计,采用问卷调查法收集资料。数据是从在达累斯萨拉姆大学和穆希比利卫生与相关科学大学学习的18岁及以上使用公共交通工具的一年级女本科生中收集的。结果:公交性骚扰总体发生率为88%。研究参与者报告的性骚扰程度最高(91%)。言语骚扰是最常见的性骚扰形式(95%),大多数学生(78%)报告称被称为“宝贝”、“甜心”、“甜心”或“爱”等名字。与公共交通工具上的性骚扰相关的因素是:车辆拥挤(AOR=2.90, 95% CI: 0.09-4.50)和使用公共交通工具作为一种交通方式(AOR=4.54, 95% CI: 0.40-8.90)。结论:研究结果强调,需要通过提高认识运动和在公共场所实施现代监测和报告系统,对性骚扰问题实施合理的干预措施。
{"title":"Sexual harassment in public transport among female university students in Dar es Salaam, Tanzania","authors":"I. Mosha, Grace Mapunda, Christopher H Mbotwa, T. Nyamhanga","doi":"10.4314/thrb.v23i4.4","DOIUrl":"https://doi.org/10.4314/thrb.v23i4.4","url":null,"abstract":"Background: Globally, women and girls are subjected to various forms of sexual harassment while using public transport daily. \u0000Objective: To determine the prevalence of sexual harassment and identify different forms and associated risk factors among female university students who use public transport in Dar es Salaam, Tanzania. \u0000Methods: A cross-sectional study design using a questionnaire was employed to collect data. Data were collected from female first-year undergraduate students, who use public transport and are aged 18 years and above studying at the University of Dar es Salaam and Muhimbili University of Health and Allied Sciences.      \u0000Results: The overall prevalence of sexual harassment on public transport was 88%. Study participants reported the highest levels of sexual harassment (91%). Verbal harassment was the most common form of sexual harassment (95%), and being called names such as baby, sweet, honey or love was reported by most students (78%). Factors associated with sexual harassment on public transport were: overcrowded vehicles (AOR=2.90, 95% CI: 0.09-4.50) and use of public transport as a form of transport (AOR=4.54, 95% CI: 0.40-8.90). \u0000 Conclusion: The study findings highlight the need for the implementation of plausible interventions on the issue of sexual harassment through awareness campaigns and the implementation of modern surveillance and reporting systems in public spaces.","PeriodicalId":39815,"journal":{"name":"Tanzania Journal of Health Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44568492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Candida auris: a literature review 耳念珠菌:文献综述
Q4 Medicine Pub Date : 2022-09-27 DOI: 10.4314/thrb.v23i4.2
D. G. Kramer, M. L. D. da Silva, Anésio M. de Sousa, Geraldo B. C. Junior, Luiz A. M. Filho
Background: Emerging pathogen Candida auris has been associated with nosocomial outbreaks demonstrating widespread antifungal resistance. This microorganism is associated with systemic infections with a high mortality rate, and studies that contribute to a better understanding of this agent are important. Objectives: The present article aimed to carry out bibliographic research on Candida auris. Therefore, a literature search was carried out between January 2018 and January 2022, applying the following: C. auris; Candida auris and Infection, in Portuguese, English and Spanish. This review considers the available literature on C. auris and highlights key unknowns, which will provide guidance for future work in this field. Results: The data collected in the present review allowed us to divide the theme into topics on Pathophysiology, Epidemiology/clinical and drug resistance mechanisms, so that the understanding of Candida auris can be better detailed and understood. Conclusion: The predilection of C. auris by the most vulnerable and immunosuppressed patients or with comorbidities and with the potential to cause invasive and bloodstream infections with a propensity to cause outbreaks and concerns regarding resistance to antifungal agents, the fungus Candida auris, is of increasing clinical relevance. The increase in the number of detected cases and the occurrence of strains with multiple drug resistance prove to be worrisome, and applied research is essential to contribute to the knowledge of this strain and effective therapy.
背景:新出现的病原体耳念珠菌与医院爆发有关,表现出广泛的抗真菌耐药性。这种微生物与死亡率高的系统性感染有关,有助于更好地了解这种病原体的研究很重要。目的:对耳念珠菌进行文献研究。因此,在2018年1月至2022年1月期间进行了文献检索,应用了以下内容:C.auris;耳念珠菌与感染,葡萄牙语、英语和西班牙语。这篇综述考虑了有关金黄色葡萄球菌的现有文献,并强调了关键的未知因素,这将为该领域的未来工作提供指导。结果:本综述中收集的数据使我们能够将主题分为病理生理学、流行病学/临床和耐药性机制等主题,以便更好地详细和理解耳念珠菌。结论:最易受感染和免疫抑制的患者或有合并症的患者更倾向于耳念珠菌,并有可能引起侵袭性和血液感染,有可能引起疫情爆发,并担心对抗真菌药物耳念珠菌的耐药性,这一点在临床上越来越重要。检测到的病例数量的增加和多重耐药性菌株的出现令人担忧,应用研究对于了解这种菌株和有效治疗至关重要。
{"title":"Candida auris: a literature review","authors":"D. G. Kramer, M. L. D. da Silva, Anésio M. de Sousa, Geraldo B. C. Junior, Luiz A. M. Filho","doi":"10.4314/thrb.v23i4.2","DOIUrl":"https://doi.org/10.4314/thrb.v23i4.2","url":null,"abstract":"Background: Emerging pathogen Candida auris has been associated with nosocomial outbreaks demonstrating widespread antifungal resistance. This microorganism is associated with systemic infections with a high mortality rate, and studies that contribute to a better understanding of this agent are important. \u0000Objectives: The present article aimed to carry out bibliographic research on Candida auris. Therefore, a literature search was carried out between January 2018 and January 2022, applying the following: C. auris; Candida auris and Infection, in Portuguese, English and Spanish. This review considers the available literature on C. auris and highlights key unknowns, which will provide guidance for future work in this field. \u0000Results: The data collected in the present review allowed us to divide the theme into topics on Pathophysiology, Epidemiology/clinical and drug resistance mechanisms, so that the understanding of Candida auris can be better detailed and understood. \u0000Conclusion: The predilection of C. auris by the most vulnerable and immunosuppressed patients or with comorbidities and with the potential to cause invasive and bloodstream infections with a propensity to cause outbreaks and concerns regarding resistance to antifungal agents, the fungus Candida auris, is of increasing clinical relevance. The increase in the number of detected cases and the occurrence of strains with multiple drug resistance prove to be worrisome, and applied research is essential to contribute to the knowledge of this strain and effective therapy.","PeriodicalId":39815,"journal":{"name":"Tanzania Journal of Health Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44850317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Magnitude and factors associated with pre-diagnosis loss to follow-up among tuberculosis presumptive patients in the Cycle of Health Care, Musoma, Tanzania: Cross-sectional study 坦桑尼亚穆索马卫生保健周期中结核病推定患者诊断前随访损失的程度和相关因素:横断面研究
Q4 Medicine Pub Date : 2022-08-13 DOI: 10.4314/thrb.v23i2.7
N. Mgina, Godfrey Elias, Kimaro Godfather, Shemtandulo Ramadhan, Sandi Erica, Mfinanga Sayoki, Ngadaya Esther, Shirima Raymond
Background: Despite National Tuberculosis (TB) Program efforts on tuberculosis control in the country, pre-diagnosis loss to follow-up is still a major problem. The study aims at exploring the magnitude and risk factors of presumptive TB cases who either do not submit a second sputum sample or do not show up for their laboratory results. Methods: The study included presumptive TB registered at the Musoma Regional Referral Hospital between May and November 2014.  Lost to follow up presumptive TB were then traced and interviewed from December 2014 to April 2015. One hundred and thirty-two among those who submitted both samples and showed up for their results were randomly selected as a comparison group.  Results: A total of 620 presumptive TB was registered at the Musoma Regional Referral Hospital (MRRH), of which 521 (84.0%) completed TB testing in accordance with the national TB diagnostic algorithm while 99 (16.0%) did not complete. Out of those who did not complete, 65 (65.7%) submitted only one spot sample and 34 (34.3%) submitted both but all of these did not pick-up their results. The Mean age of participants was 45.3 years (Standard deviation 17.7). The main reasons for loss to follow-up were: 23 (23.2%) opted to go to other health care facilities; 23 (23.2%) lack of transport fare; and 20 (20.2%) long distance to the hospital. Males were 1.6 (95%CI1.02-2.90) more likely to complete TB diagnostic algorithm.
背景:尽管国家结核病规划署在该国努力控制结核病,但诊断前随访失败仍然是一个主要问题。这项研究旨在探讨未提交第二份痰液样本或未出现实验室结果的推定结核病病例的数量和风险因素。方法:该研究包括2014年5月至11月在Musoma地区转诊医院登记的推定结核病。然后在2014年12月至2015年4月追踪和访谈失访推定结核病。在提交两份样本并出示结果的人中,有132人被随机选为对照组。结果:穆索马地区转诊医院共登记了620例推定结核病,其中521例(84.0%)根据国家结核病诊断算法完成了结核病检测,99例(16.0%)未完成。在那些没有完成的人中,65人(65.7%)只提交了一个现场样本,34人(34.3%)同时提交了两个样本,但所有这些都没有得到结果。参与者的平均年龄为45.3岁(标准差17.7)。失去随访的主要原因是:23人(23.2%)选择去其他医疗机构;23人(23.2%)缺乏交通费;距离医院较远者20例(20.2%)。男性完成结核病诊断算法的可能性高1.6(95%CI1.02-2.90)。
{"title":"Magnitude and factors associated with pre-diagnosis loss to follow-up among tuberculosis presumptive patients in the Cycle of Health Care, Musoma, Tanzania: Cross-sectional study","authors":"N. Mgina, Godfrey Elias, Kimaro Godfather, Shemtandulo Ramadhan, Sandi Erica, Mfinanga Sayoki, Ngadaya Esther, Shirima Raymond","doi":"10.4314/thrb.v23i2.7","DOIUrl":"https://doi.org/10.4314/thrb.v23i2.7","url":null,"abstract":"Background: Despite National Tuberculosis (TB) Program efforts on tuberculosis control in the country, pre-diagnosis loss to follow-up is still a major problem. The study aims at exploring the magnitude and risk factors of presumptive TB cases who either do not submit a second sputum sample or do not show up for their laboratory results. \u0000Methods: The study included presumptive TB registered at the Musoma Regional Referral Hospital between May and November 2014.  Lost to follow up presumptive TB were then traced and interviewed from December 2014 to April 2015. One hundred and thirty-two among those who submitted both samples and showed up for their results were randomly selected as a comparison group.  \u0000Results: A total of 620 presumptive TB was registered at the Musoma Regional Referral Hospital (MRRH), of which 521 (84.0%) completed TB testing in accordance with the national TB diagnostic algorithm while 99 (16.0%) did not complete. Out of those who did not complete, 65 (65.7%) submitted only one spot sample and 34 (34.3%) submitted both but all of these did not pick-up their results. The Mean age of participants was 45.3 years (Standard deviation 17.7). The main reasons for loss to follow-up were: 23 (23.2%) opted to go to other health care facilities; 23 (23.2%) lack of transport fare; and 20 (20.2%) long distance to the hospital. Males were 1.6 (95%CI1.02-2.90) more likely to complete TB diagnostic algorithm.","PeriodicalId":39815,"journal":{"name":"Tanzania Journal of Health Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43629734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of gross morphological and histological features of placenta between hypertensive and normotensive pregnant women attending Muhimbili National Hospital. Muhimbili国立医院高血压和血压正常孕妇胎盘大体形态学和组织学特征的比较。
Q4 Medicine Pub Date : 2022-08-10 DOI: 10.4314/thrb.v23i2.3
Antpas Furaha, Dennis Russa
Background: Placenta is the vital fetomaternal organ that is responsible for the maintenance of the pregnancy and promotion of fetal growth and development. The optimal survival, growth, and development of the fetus correspond to the appropriate formation and development of the placenta. Hypertensive disorders of pregnancy exert a great impact on the placenta and reflect changes both morphological and histological.  Objective: To compare the morphological and histological features of the placenta between hypertensive pregnant mothers and non-hypertensive pregnant mothers who attended Muhimbili National Hospital (MNH). Methods: A hospital-based cross-sectional study was conducted from June 2020 to August 2020 at Muhimbili National Hospital (MNH).  A total of 80 placentas were studied morphologically and histologically, of which 40 placentas were from hypertensive pregnant mothers and 40 placentas were from normotensive pregnant mothers. In the morphological aspect shape, weight, the site of insertion of the umbilical cord, the number of cotyledons of each placenta and thickness of the placenta were noted. In the histological part, Neutral buffered formalin (NBF) was used the routine staining technique which was Hematoxylin and Eosin (H&E) and a light microscope was used. The data were analyzed by using SPSS version 20 computer software and the results were summarized in means and proportions. ‘T-test’ and chi-square’ tests were used and the difference was statistically significant when the p-value>0.05   Results: The irregular shape of the placenta and marginal insertion of the umbilical cord were more in the hypertensive group and were statistically significant (p>0.01). The mean placenta weight, mean placenta thickness and mean numbers of cotyledons were significantly less in a hypertensive group compared to the normotensive group (p<0.01). A microscopic study of the placenta revealed the presence of fibrinoid necrosis, syntial knots, calcifications and villous hypoplasia in both normotensive and hypertensive group however these findings were significantly higher in the hypertensive group (p>0.01). Conclusion: Hypertensive disorders of pregnancy (HDP) exert a profound impact on the placenta. Morphologically altering its dimensions and histologically fibrinoid necrosis, calcifications, syntial knots, and villous hypoplasia were significantly more in the hypertensive group than in the normotensive (p>0.01).
背景:胎盘是维持妊娠、促进胎儿生长发育的重要母胎器官。胎儿的最佳生存、生长和发育与胎盘的适当形成和发育相对应。妊娠期高血压疾病对胎盘的影响很大,反映了胎盘形态和组织学的变化。目的:比较在Muhimbili国立医院(MNH)就诊的高血压孕妇与非高血压孕妇胎盘的形态学和组织学特征。方法:2020年6月至2020年8月在Muhimbili国立医院(MNH)进行了一项基于医院的横断面研究。对80个胎盘进行形态学和组织学研究,其中高血压孕妇胎盘40个,正常孕妇胎盘40个。在形态方面,形状,重量,脐带的插入位置,每个胎盘子叶的数量和胎盘的厚度被记录。组织学部分采用中性缓冲福尔马林(NBF)染色,常规染色技术为苏木精和伊红(H&E),光镜下染色。采用SPSS 20软件对数据进行分析,并以均值和比例对结果进行汇总。结果:高血压组胎盘形状不规则、脐带边缘插入较多,差异有统计学意义(p>0.01)。高血压组胎盘平均重量、平均厚度、平均子叶数均明显少于正常组(p0.01)。结论:妊娠期高血压疾病(HDP)对胎盘有重要影响。在形态学上改变其大小,组织学上纤维蛋白样坏死、钙化、纤维结和绒毛发育不全在高血压组明显多于正常血压组(p < 0.01)。
{"title":"Comparison of gross morphological and histological features of placenta between hypertensive and normotensive pregnant women attending Muhimbili National Hospital.","authors":"Antpas Furaha, Dennis Russa","doi":"10.4314/thrb.v23i2.3","DOIUrl":"https://doi.org/10.4314/thrb.v23i2.3","url":null,"abstract":"Background: Placenta is the vital fetomaternal organ that is responsible for the maintenance of the pregnancy and promotion of fetal growth and development. The optimal survival, growth, and development of the fetus correspond to the appropriate formation and development of the placenta. Hypertensive disorders of pregnancy exert a great impact on the placenta and reflect changes both morphological and histological. \u0000 Objective: To compare the morphological and histological features of the placenta between hypertensive pregnant mothers and non-hypertensive pregnant mothers who attended Muhimbili National Hospital (MNH). \u0000Methods: A hospital-based cross-sectional study was conducted from June 2020 to August 2020 at Muhimbili National Hospital (MNH).  A total of 80 placentas were studied morphologically and histologically, of which 40 placentas were from hypertensive pregnant mothers and 40 placentas were from normotensive pregnant mothers. In the morphological aspect shape, weight, the site of insertion of the umbilical cord, the number of cotyledons of each placenta and thickness of the placenta were noted. In the histological part, Neutral buffered formalin (NBF) was used the routine staining technique which was Hematoxylin and Eosin (H&E) and a light microscope was used. The data were analyzed by using SPSS version 20 computer software and the results were summarized in means and proportions. ‘T-test’ and chi-square’ tests were used and the difference was statistically significant when the p-value>0.05 \u0000  \u0000Results: The irregular shape of the placenta and marginal insertion of the umbilical cord were more in the hypertensive group and were statistically significant (p>0.01). The mean placenta weight, mean placenta thickness and mean numbers of cotyledons were significantly less in a hypertensive group compared to the normotensive group (p<0.01). A microscopic study of the placenta revealed the presence of fibrinoid necrosis, syntial knots, calcifications and villous hypoplasia in both normotensive and hypertensive group however these findings were significantly higher in the hypertensive group (p>0.01). \u0000Conclusion: Hypertensive disorders of pregnancy (HDP) exert a profound impact on the placenta. Morphologically altering its dimensions and histologically fibrinoid necrosis, calcifications, syntial knots, and villous hypoplasia were significantly more in the hypertensive group than in the normotensive (p>0.01).","PeriodicalId":39815,"journal":{"name":"Tanzania Journal of Health Research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42728362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Tanzania Journal of Health Research
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1