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Chronic venous diseases and obesity: pathogenetically based treatment and prevention options 慢性静脉疾病与肥胖:基于病因的治疗和预防方案
Pub Date : 2024-05-17 DOI: 10.21518/akh2024-014
B. Boldin, B. Boldin, G. A. Varich, O. V. Dzhenina, R. Abdosh
This literature review analyzes relationships and correlations between obesity and chronic venous diseases. The search of scien tific publications was carried out in the Cochrane Library, PubMed, Medscape and Medline databases in accordance with the PRISMA guidelines. The review includes only publications, which were particularly relevant to our focus of research and where a significance difference between “experience and control” groups was found based on the results of statistical analysis. All studies included in the analysis defined obesity as a body mass index of 30.0 kg/m2 or more, and overweight as a BMI from 25 to 30 kg/m2 according to the criteria of the World Health Organization. The findings of publication analysis show that excess body weight, and especially obesity, is a major independent risk factor for the development and progression of chronic venous diseases and their complications. In addition, a direct cause-and-effect relationship between body weight and the severity of chronic venous insufficiency was observed. Increased intra-abdominal pressure associated with the visceral fat deposition is one of the key features of the pathogenesis of chronic venous diseases in patients with overweight and obesity. In this context, bariatric surgery, after which weight loss correlates with falling into a lower clinical class of chronic venous diseases is the most effective method for improving phlebological status. Along with bariatric surgery, the pharmacotherapeutic options are considered in patients with chronic venous diseases with underlying overweight and burdened comorbidities anamnesis. In this regard, the role of hesperidin combined and diosmin that have been shown to be most effective phlebotropic drug is discussed. Recent studies demonstrate that hesperidin has independent pluripotent properties, among which the mechanisms of action of this substance on lipid metabolism accompanied by a decrease in subjects’ body weight and visceral fat volume are a matter of interest. After completion of full-fledged clinical studies this action of hesperidin can be implemented in various treatment-and-prophylactic protocols on the management of patients with chronic venous diseases, related to underlying overweight and morbid obesity. Venarus® contains two micronized components hesperidin and diosmin at standardized dosages: 10% hesperidin and 90% diosmin, which can be used as an argument in favour of choosing this drug to treat patients with chronic venous diseases, related to underlying obesity or overweight.
本文献综述分析了肥胖与慢性静脉疾病之间的关系和相关性。根据 PRISMA 指南,我们在 Cochrane 图书馆、PubMed、Medscape 和 Medline 数据库中对科学出版物进行了检索。综述仅包括与我们的研究重点特别相关,且根据统计分析结果发现 "经验组和对照组 "之间存在显著差异的出版物。根据世界卫生组织的标准,所有纳入分析的研究都将肥胖定义为体重指数达到或超过 30.0 kg/m2,将超重定义为体重指数在 25 至 30 kg/m2 之间。出版物的分析结果表明,超重,尤其是肥胖,是慢性静脉疾病及其并发症发生和发展的主要独立风险因素。此外,体重与慢性静脉功能不全的严重程度之间存在直接的因果关系。与内脏脂肪沉积有关的腹内压增高是超重和肥胖患者慢性静脉疾病发病机制的主要特征之一。在这种情况下,减肥手术是改善静脉状况最有效的方法。在进行减肥手术的同时,还要考虑对患有慢性静脉疾病、潜在体重超标和有严重并发症的患者进行药物治疗。在这方面,我们讨论了橙皮甙联合地奥司明的作用,它们已被证明是最有效的降血脂药物。最近的研究表明,橙皮甙具有独立的多能性,其中这种物质对脂质代谢的作用机制,以及伴随着受试者体重和内脏脂肪体积的减少是一个值得关注的问题。在完成全面的临床研究后,橙皮甙的这一作用可应用于各种治疗和预防方案中,用于治疗与潜在超重和病态肥胖有关的慢性静脉疾病患者。Venarus® 含有两种微粉化成分橙皮甙和薯蓣皂苷,剂量均已标准化:10%的橙皮甙和90%的薯蓣皂苷可以作为支持选择这种药物治疗与潜在肥胖或超重有关的慢性静脉疾病患者的论据。
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引用次数: 0
Optimization of treatment of patients with inguinal hernia in combination with recurrence of varicose veins 腹股沟疝合并静脉曲张复发患者的最佳治疗方法
Pub Date : 2024-05-17 DOI: 10.21518/akh2024-006
V. E. Milyukov, A. Chernookov, S. Kandyba, N. O. Bartosh, O. M. Dondup, А. A. Atayan, A. A. Ramazanov, A. Z. Pshmakhova, T. I. Shadyzheva
Introduction. In recent years, surgeons have increasingly used combined operations in patients with inguinal hernias and recurrent varicose veins. However, it is necessary to justify the choice of the type and volume of the main and concomitant stages of combined surgery, depending on the individual characteristics of both diseases.Aim. Optimization of surgical treatment of patients with inguinal hernias in combination with relapses of varicose veins.Materials and methods. The study included 39 patients aged 35 to 78 years with inguinal hernias and RVB. Of these, 21 patients who underwent combined operations were included in the main group. The control group included 18 patients who underwent staged hernioplasty, and then after 1–26 months, operations for RVB, or interventions were performed in reverse order. A comparative assessment of the duration of operations, the level of postoperative pain, immediate and long-term results, and the number of complications of uncorrected diseases in two-stage treatment was carried out.Results and discussion. Performing combined operations in this category of patients does not lead to an increase in the level of postoperative complications, it is accompanied by an average increase in the duration of surgery by 33.6 minutes and an increase in the intensity of postoperative pain by 0.8 points, a decrease in temporary disability by 1.2 times.Conclusions. Performing combined operations is the optimal intervention in patients with inguinal hernias with concomitant recurrence of varicose veins. The use of combined operations makes it possible to simultaneously eliminate both diseases and exclude the development of complications from an uncorrected disease, which, with two-stage treatment, was observed in 11.1% of cases and required emergency operations.
简介近年来,外科医生越来越多地对腹股沟疝和复发性静脉曲张患者采用联合手术。然而,有必要根据两种疾病的个体特征,合理选择联合手术主要阶段和伴随阶段的类型和手术量。优化腹股沟疝合并静脉曲张复发患者的手术治疗。研究纳入了 39 名腹股沟疝合并 RVB 患者,年龄在 35 岁至 78 岁之间。其中,21 名接受联合手术的患者被纳入主组。对照组包括 18 名患者,他们接受了分期疝成形术,然后在 1-26 个月后接受 RVB 手术,或以相反的顺序进行干预。对两阶段治疗的手术时间、术后疼痛程度、近期和远期效果以及未纠正疾病的并发症数量进行了比较评估。对这类患者实施联合手术不会导致术后并发症的增加,但手术时间平均增加了 33.6 分钟,术后疼痛强度增加了 0.8 点,暂时性残疾减少了 1.2 倍。对于腹股沟疝同时伴有静脉曲张复发的患者,实施联合手术是最佳干预措施。采用联合手术可同时消除两种疾病,并排除未纠正疾病引起的并发症,在采用两阶段治疗的病例中,有11.1%的患者需要进行紧急手术。
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引用次数: 0
From the experience of more than 1000 glue ablation procedures for varicose veins: how to do it 1000 多例静脉曲张胶水消融术的经验:如何操作
Pub Date : 2024-05-17 DOI: 10.21518/akh2024-004
О. Shirinbek
Cyanoacrylate adhesive closure (CAC) is currently one of the main non-thermal ablation modalities of incompetent saphenous veins. High efficacy and safety of the method is supported by international clinical practice guidelines as well as the real-world practice. In contrast to thermal ablation, CAC is advantageous in terms of low periprocedural pain and bruising, fast procedure time and postprocedural recovery, high patient comfort and satisfaction rates as well as avoidance of postprocedural compression. This publication summarises the practical tips and tricks of glue ablation procedure based on 5-year experience (2019–2023) at the “SM-Clinic” Phlebology Centre, Moscow. Indications for the preferred use of CAC are formulated, such as: low pain threshold; contraindications (or unwillingness) to postprocedural compression; extensive comorbidity and fragile patients; concomitant morbid obesity; the presence of axial reflux along the saphenous veins; the need for simultaneous ablation of several incompetent truncal veins; below-the-knee incompetence of saphenous veins, including recurrent varicose veins; extensive lipodermatosclerosis and/or venous leg ulcer; patient’s HIV and viral hepatitis positive status. A step-by-step interventional protocol of glue ablation is described, including the modified protocols of the procedure. The immediate and long-term outcomes of the CAC according to current data are discussed. Special attention is paid to adverse events following CAC, as well as technical aspects of their prevention. Despite high efficacy and safety profile, today’s limitations for adoption and wider use of CAC are cost issues and lack of reimbursement.
氰基丙烯酸酯粘合剂闭合术(CAC)是目前治疗无功能隐静脉的主要非热消融方法之一。该方法的高效性和安全性得到了国际临床实践指南和实际应用的支持。与热消融术相比,CAC 在以下方面具有优势:术后疼痛和瘀伤少、手术时间短、术后恢复快、患者舒适度和满意度高以及避免术后压迫。本刊物根据莫斯科 "SM-Clinic "静脉中心 5 年(2019-2023 年)的经验,总结了胶水消融术的实用技巧和窍门。其中提出了首选使用 CAC 的指征,如疼痛阈值低;有术后压迫禁忌症(或不愿接受术后压迫);合并症多且体质脆弱的患者;合并病态肥胖;存在隐静脉轴向回流;需要同时消融多条闭锁的躯干静脉;膝下隐静脉闭锁,包括复发性静脉曲张;大面积脂肪性皮肤硬化和/或静脉性腿部溃疡;患者的艾滋病毒和病毒性肝炎呈阳性。本文介绍了胶水消融术的逐步介入方案,包括该手术的改良方案。根据目前的数据,讨论了 CAC 的近期和远期疗效。还特别关注了 CAC 术后的不良反应以及预防不良反应的技术问题。尽管 CAC 具有很高的疗效和安全性,但目前采用和广泛使用 CAC 的限制因素是成本问题和缺乏报销。
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引用次数: 0
Sclerosing mesenteritis as a surgical problem: a review of the literature and own clinical observation 作为外科问题的硬化性肠系膜炎:文献综述与临床观察
Pub Date : 2024-05-17 DOI: 10.21518/akh2024-001
V. Bogachev, B. Boldin, P. Y. Golosnitskiy, P. Turkin, I. M. Dizengof, D. A. Kobzarev, V. Y. Tsukan
The problem of studying the pathology of mesenteric fat of the small intestine in surgical practice has not yet received enough attention. A number of questions remain unresolved regarding the etiology and pathogenesis of mesenteric diseases, their possible connection with benign and malignant diseases, methods of their laboratory and instrumental diagnosis, possible options for conservative and surgical treatment, as well as systematization and structuring of the classification. One of the poorly studied representatives of diseases of the mesentery of the small intestine continues to be Sclerosing mesenteritis, characterized by various histological variants of damage to mesenteric fat and a varied nonspecific clinical picture. Taken together, this leads to certain difficulties in diagnosis, patients seeking access to doctors of various profiles, which ultimately negatively affects the results of treatment and can lead to social maladjustment and possible disability. Reports on the occurrence of this pathology in the medical literature are few and, as a rule, describe extremely rare clinical cases. However, in recent years, the frequency of detection of this pathology continues to grow steadily, which is associated with the progressive aging of the population, a high degree of surgical activity in relation to urgent diseases of the abdominal organs, and the improvement of instrumental diagnostic methods. Issues of etiology, pathogenesis, differential diagnosis of this disease and its possible connection with the paraneoplastic process currently continue to cause debate. Further accumulation of clinical experience, a better understanding of the pathogenesis of the disease, and improvement of imaging techniques will allow us to develop clearer diagnostic and clinical criteria, narrow the diagnostic search and, ultimately, improve and standardize treatment. The article provides a review of the literature on this rare surgical pathology, presents our own clinical observation, and discusses diagnostic issues and treatment options for this disease.
在外科实践中,研究小肠肠系膜脂肪病理学的问题尚未得到足够重视。在肠系膜疾病的病因和发病机制、与良性和恶性疾病的可能联系、实验室和仪器诊断方法、保守治疗和手术治疗的可能选择以及分类的系统化和结构化等方面,仍有许多问题尚未解决。硬化性肠系膜炎仍然是小肠系膜疾病中研究较少的代表之一,其特点是肠系膜脂肪受损的组织学变异和非特异性的临床表现各不相同。总之,这给诊断带来了一定的困难,病人需要求助于各种不同的医生,最终对治疗效果产生负面影响,并可能导致社会适应不良和残疾。医学文献中关于这种病症发生的报道很少,通常描述的都是极为罕见的临床病例。然而,近年来,这种病症的发现频率持续稳步增长,这与人口老龄化的加剧、腹部器官急症的外科手术频繁以及仪器诊断方法的改进有关。这种疾病的病因、发病机制、鉴别诊断及其与副肿瘤过程的可能联系等问题目前仍在争论之中。临床经验的进一步积累、对该病发病机制的进一步了解以及影像学技术的改进将使我们能够制定更明确的诊断和临床标准,缩小诊断范围,并最终改进和规范治疗。本文回顾了有关这种罕见外科病理的文献,介绍了我们自己的临床观察结果,并讨论了这种疾病的诊断问题和治疗方案。
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引用次数: 0
Endovenous laser obliteration of the lower extremity veins: there is a time and place 下肢静脉的静脉腔内激光阻断术:有其时间和地点限制
Pub Date : 2024-05-16 DOI: 10.21518/akh2024-017
D. S. Zubkov
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引用次数: 0
Experts’ views on recurrence and progression of varicose veins 专家对静脉曲张复发和恶化的看法
Pub Date : 2024-05-16 DOI: 10.21518/akh2024-015
V. Bogachev, O. A. Alukhanyan, G. N. Vanyan, S. M. Markin, A. S. Artemova, P. F. Kravtsov
Introduction. Despite modern advances in technologies for the treatment and prevention of varicose veins, there is currently no radical treatment for varicose veins. The probability of recurrence of dilated veins, according to various authors, ranges from 5 to 70%. Along with the well-established concept of recurrence of varicose veins, the term progression of varicose veins is increasingly common in everyday life.Aim. To study the current understanding of the term relapse and the practical attitude of specialists involved in the treatment of varicose veins to it.Material and methods. In 2023, a survey of 117 specialists on the recurrence/progression of varicose veins was conducted. The respondents were doctors involved in the treatment of varicose veins: vascular surgeons 22.4%, phlebologists 50%, general surgeons 19.8%, specialists in ultrasound/functional diagnostics 7.8%, X-ray endovascular surgeon 0.85%. The questionnaire included 18 questions regarding the frequency of visits of patients with relapse/progression of varicose veins; views on tactics, as well as the attitude of specialists to the issue of progression and recurrence of varicose veins in patients after its surgical treatment.Results and discussion. The concept of recurrence and progression of varicose veins among specialists dealing with this pathology is not always comparable. There are differences in views both on the predisposing factors for the recurrence of dilated veins, and, accordingly, on the tactics of treatment and preventive measures. In some cases, according to statistics, they are due to specialization.Conclusions. The incidence of relapse and progression at the reception of the respondents has a slight difference. Despite the fact that there are opinions that do not correspond to generally accepted and abhorrent collegiality, mostly specialists try to separate these concepts, see differences in provoking factors and, accordingly, in recommendations.
导言。尽管现代治疗和预防静脉曲张的技术不断进步,但目前还没有根治静脉曲张的方法。根据不同学者的研究,扩张静脉的复发概率在 5% 至 70% 之间。随着静脉曲张复发概念的确立,静脉曲张进展一词在日常生活中也越来越常见。研究目前对复发一词的理解,以及参与静脉曲张治疗的专家对复发的实际态度。2023 年,对 117 名专家进行了关于静脉曲张复发/进展的调查。调查对象为参与静脉曲张治疗的医生:血管外科医生占 22.4%,静脉内科医生占 50%,普通外科医生占 19.8%,超声/功能诊断专家占 7.8%,X 射线血管内外科医生占 0.85%。调查问卷包括18个问题,涉及静脉曲张复发/进展患者的就诊频率、对战术的看法以及专家对手术治疗后静脉曲张进展和复发问题的态度。治疗静脉曲张的专科医生对静脉曲张复发和恶化的概念并不总是一致的。无论是在静脉扩张复发的诱发因素上,还是在治疗策略和预防措施上,都存在着不同的观点。据统计,在某些情况下,这些差异是由专业化造成的。受访者复发和恶化的发生率略有不同。尽管有些意见与普遍接受的和令人憎恶的合议意见不一致,但大多数专家都试图将这些概念分开,看到诱发因素的差异,并据此提出建议。
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引用次数: 0
Comparative morphological and morphometric analysis of the structure of the wall of the calf venous collectors 小腿静脉收集器壁结构的形态学和形态计量学比较分析
Pub Date : 2024-05-16 DOI: 10.21518/akh2024-012
A. B. Sannikov, O. N. Morozova, E. Shaydakov
Introduction. Development of venous pathology of the lower extremities is based on morphological changes in the vascular wall. Further structural restructuring of the vein wall in chronic venous insufficiency will depend on the initially present differences in the structure of their walls.Aim. To conduct a comparative analysis of morphological and morphometric features of the structure of the walls of the main venous collectors of the lower leg: the great saphenous vein, intramuscular veins, posterior tibia veins and poplitea vein.Materials and methods. Histological studies were carried out on autopsy material of the veins of 32 people who died from various causes aged 35 to 50 years and 10 amputated limbs. Morphological studies of the venous wall were carried out by light microscopy with digital photo processing.Results. A quantitative comparative analysis of morphological changes with the determination of the volume fraction of smooth muscle and connective tissue elements of various membranes of the venous wall, as well as measurement of the total thickness of the vascular wall and its ratio to the lumen of the veins showed statistically significant differences at a significance level of p < 0.05.Discussion. Despite the similarity of the general morphological picture of the structure of various venous collectors of the lower leg, structural differences were established, which concerned the volume fraction of the presence of both smooth muscle and connective tissue elements.Conclusion. The comparative qualitative and quantitative statistical analysis of morphological and morphometric features of the structure of the walls of the main venous collectors of the lower leg allows us to make an assumption about the unequal role of individual main venous collectors in the work of the muscular-venous pump of the lower leg as a whole.
简介下肢静脉病变的发展基于血管壁的形态变化。慢性静脉功能不全时静脉壁结构的进一步重组将取决于静脉壁结构最初存在的差异。对小腿大隐静脉、肌内静脉、胫后静脉和腘静脉等主要静脉集血管壁结构的形态学和形态计量学特征进行比较分析。对 32 名因各种原因死亡的 35 至 50 岁的人和 10 名截肢者的静脉解剖材料进行了组织学研究。通过光镜和数码照片处理对静脉壁进行形态学研究。通过测定静脉壁各种膜的平滑肌和结缔组织成分的体积分数,以及测量血管壁的总厚度及其与静脉管腔的比例,对形态变化进行定量比较分析,结果表明,在显著性水平 p < 0.05 的情况下,差异具有统计学意义。尽管小腿各种静脉收集器结构的总体形态相似,但在结构上存在差异,这与平滑肌和结缔组织成分的体积分数有关。通过对小腿主要静脉集血管壁结构的形态学和形态计量学特征进行定性和定量统计对比分析,我们可以推测,在小腿肌肉-静脉泵的整体工作中,各个主要静脉集血管发挥着不平等的作用。
{"title":"Comparative morphological and morphometric analysis of the structure of the wall of the calf venous collectors","authors":"A. B. Sannikov, O. N. Morozova, E. Shaydakov","doi":"10.21518/akh2024-012","DOIUrl":"https://doi.org/10.21518/akh2024-012","url":null,"abstract":"Introduction. Development of venous pathology of the lower extremities is based on morphological changes in the vascular wall. Further structural restructuring of the vein wall in chronic venous insufficiency will depend on the initially present differences in the structure of their walls.Aim. To conduct a comparative analysis of morphological and morphometric features of the structure of the walls of the main venous collectors of the lower leg: the great saphenous vein, intramuscular veins, posterior tibia veins and poplitea vein.Materials and methods. Histological studies were carried out on autopsy material of the veins of 32 people who died from various causes aged 35 to 50 years and 10 amputated limbs. Morphological studies of the venous wall were carried out by light microscopy with digital photo processing.Results. A quantitative comparative analysis of morphological changes with the determination of the volume fraction of smooth muscle and connective tissue elements of various membranes of the venous wall, as well as measurement of the total thickness of the vascular wall and its ratio to the lumen of the veins showed statistically significant differences at a significance level of p < 0.05.Discussion. Despite the similarity of the general morphological picture of the structure of various venous collectors of the lower leg, structural differences were established, which concerned the volume fraction of the presence of both smooth muscle and connective tissue elements.Conclusion. The comparative qualitative and quantitative statistical analysis of morphological and morphometric features of the structure of the walls of the main venous collectors of the lower leg allows us to make an assumption about the unequal role of individual main venous collectors in the work of the muscular-venous pump of the lower leg as a whole.","PeriodicalId":398195,"journal":{"name":"Ambulatornaya khirurgiya = Ambulatory Surgery (Russia)","volume":" 1219","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141127409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The effectiveness of minimally invasive surgical techniques for treating patients with chronic venous insufficiency in the stage of trophic disorders: comparative study 微创外科技术治疗营养障碍期慢性静脉功能不全患者的效果:比较研究
Pub Date : 2024-05-03 DOI: 10.21518/akh2024-018
A. Khitaryan, K. Veliev
Introduction. Despite the active introduction of minimally invasive techniques into modern phlebology, the problem of surgical treatment of chronic venous insufficiency (CVI) in the stage of trophic disorders is still far from being finally resolved, especially problems of horizontal reflux.Aim. Тo comparatively evaluate the results of using various tactics of minimally invasive surgical treatment in patients with lower extremitiesʹs CVI in the stage of trophic disorders.Materials and methods. A study at 139 patients with CVI at the stage of trophic disorders was carried out. Group 1 (n = 79) included patients who underwent endovasal laser coagulation of the trunks of the great and small saphenous veins (GSV and SSV) with microfoam sclerotherapy of varicose perforating veins. In group 2 (n = 60) – method of intervention was determined by the diameter of Cockettʹs perforants.Results. Indicators of the early postoperative period in the study groups were comparable. After 2 months, no cases of relapse in the GSV and SSV were registered. Recurrence of horizontal reflux was observed only in 6 (7.6%) people in group 1. In long-term postoperative follow-up, decrease in the severity of the disease according to the VCSS scale was found in both groups (p < 0.001). The persistence of pathological reflux along was observed in 16 (22.5%) patients of group 1. Moreover, in 62.5% and 68.75% cases of relapses, the perforants had, respectively, a large diameter and high blood flowʹs speed.Discussion. In general, minimally invasive techniques used demonstrated comparable clinical results and high efficiency. At the same time, the importance of preoperative assessment and taking into account the properties of perforants has been proven.Conclusion. The claimed method should be considered as an effective and safety method of obliteration of incompetent perforating veins at severe forms of CVI.
导言。尽管微创技术被积极引入现代静脉学,但营养障碍阶段慢性静脉功能不全(CVI)的手术治疗问题仍远未得到最终解决,尤其是水平回流问题。比较评估对营养障碍期下肢慢性静脉功能不全(CVI)患者采用各种微创手术治疗方法的效果。对139名处于营养障碍期的CVI患者进行了研究。第1组(79人)包括对大隐静脉和小隐静脉主干(GSV和SSV)进行血管内激光凝固术,并对曲张的穿孔静脉进行微泡沫硬化治疗的患者。第2组(n = 60)--干预方法根据Cockettʹs穿孔的直径确定。研究组术后早期的各项指标相当。两个月后,GSV 和 SSV 均无复发病例。在术后长期随访中,根据 VCSS 量表,两组患者的病情严重程度均有所下降(P < 0.001)。此外,62.5%和68.75%的复发病例的穿孔直径较大,血流速度较快。总的来说,微创技术的临床效果和效率都相当高。同时,术前评估和考虑穿孔特性的重要性也得到了证实。在严重的 CVI 病例中,上述方法应被视为一种有效、安全的无功能穿孔静脉阻断方法。
{"title":"The effectiveness of minimally invasive surgical techniques for treating patients with chronic venous insufficiency in the stage of trophic disorders: comparative study","authors":"A. Khitaryan, K. Veliev","doi":"10.21518/akh2024-018","DOIUrl":"https://doi.org/10.21518/akh2024-018","url":null,"abstract":"Introduction. Despite the active introduction of minimally invasive techniques into modern phlebology, the problem of surgical treatment of chronic venous insufficiency (CVI) in the stage of trophic disorders is still far from being finally resolved, especially problems of horizontal reflux.Aim. Тo comparatively evaluate the results of using various tactics of minimally invasive surgical treatment in patients with lower extremitiesʹs CVI in the stage of trophic disorders.Materials and methods. A study at 139 patients with CVI at the stage of trophic disorders was carried out. Group 1 (n = 79) included patients who underwent endovasal laser coagulation of the trunks of the great and small saphenous veins (GSV and SSV) with microfoam sclerotherapy of varicose perforating veins. In group 2 (n = 60) – method of intervention was determined by the diameter of Cockettʹs perforants.Results. Indicators of the early postoperative period in the study groups were comparable. After 2 months, no cases of relapse in the GSV and SSV were registered. Recurrence of horizontal reflux was observed only in 6 (7.6%) people in group 1. In long-term postoperative follow-up, decrease in the severity of the disease according to the VCSS scale was found in both groups (p < 0.001). The persistence of pathological reflux along was observed in 16 (22.5%) patients of group 1. Moreover, in 62.5% and 68.75% cases of relapses, the perforants had, respectively, a large diameter and high blood flowʹs speed.Discussion. In general, minimally invasive techniques used demonstrated comparable clinical results and high efficiency. At the same time, the importance of preoperative assessment and taking into account the properties of perforants has been proven.Conclusion. The claimed method should be considered as an effective and safety method of obliteration of incompetent perforating veins at severe forms of CVI.","PeriodicalId":398195,"journal":{"name":"Ambulatornaya khirurgiya = Ambulatory Surgery (Russia)","volume":"17 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141016876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dynamics of sarcopenia after Roux-en-Y gastric bypass in patients with morbid obesity 病态肥胖症患者进行 Roux-en-Y 胃旁路术后肌少症的动态变化
Pub Date : 2023-12-20 DOI: 10.21518/akh2023-043
A. Khitaryan, A. Abovyan, A. Mezhunts, A. Orekhov, R. V. Karukes, A. A. Rogut, V. Khitaryan
Introduction. Roux-en-Y gastric bypass (RYGB) is one of the most popular bariatric procedures. However, the Impact of alimentary and biliopancreatic loops lengths on the results of Roux-En-Y Gastric Bypass with a maximum restrictive component remains insufficiently studied.Aim. To compare the long-term results of RYGB with a maximum restrictive component at different lengths of alimentary and biliopancreatic loops.Materials and methods. Our retrospective study included 170 patients: 98 (57.6%) in the group with long alimentary and biliopancreatic loops, 72 (42.4%) in the group with short loops. Follow-up examinations were carried out with a follow-up period of at least 24 months (median follow-up 38 months). In the first group, the lengths of the alimentary and biliopancreatic loops were 150 and 100 cm, in the second group – 100 and 60 cm respectively. In the preoperative period, all patients underwent a standard set of examinations with an obligatory determination of the skeletal muscle mass index using the bioelectrical impedance analysis. The size of the gastroenteroanastomosis was assessed 12 months after surgery using fibrogastroscopy.Results. Both groups showed good results in weight loss and control of associated diseases. The prevalence of moderate sarcopenia in the group of RYGB with long loops was 24.5% (19.4% in the preoperative period), severe sarcopenia was observed in 3% of the subjects (initially severe sarcopenia was not detected in any patient). In the group of RYGB with short loops, the incidence of sarcopenia increased from 13 to 16% (the difference is statistically insignificant). No pronounced sarcopenia was detected in this group after surgery.Conclusion. If patients have signs of moderate sarcopenia according to bioelectrical impedance analysis, type 2 diabetes mellitus, as well as in the elderly, it is advisable to perform RYGB with a minimal malabsorptive and maximum restrictive component.
导言。Roux-en-Y 胃旁路术(RYGB)是最流行的减肥手术之一。然而,关于消化道襻和胆胰襻长度对最大限制性 Roux-En-Y 胃旁路术效果的影响的研究仍然不足。比较不同长度的消化道襻和胆胰管襻的最大限制性RYGB术的长期效果。我们的回顾性研究包括 170 名患者:长消化道襻和胆胰襻组有98人(57.6%),短消化道襻组有72人(42.4%)。随访检查的随访时间至少为 24 个月(中位数随访时间为 38 个月)。第一组的消化道襻和胆胰襻长度分别为 150 厘米和 100 厘米,第二组分别为 100 厘米和 60 厘米。术前,所有患者都接受了一套标准检查,其中必须使用生物电阻抗分析测定骨骼肌质量指数。术后 12 个月,使用纤维胃镜对胃肠吻合口的大小进行评估。两组患者在减轻体重和控制相关疾病方面都取得了良好的效果。在使用长环路的 RYGB 组中,中度肌少症的发生率为 24.5%(术前为 19.4%),3% 的受试者出现重度肌少症(最初没有发现任何患者出现重度肌少症)。在使用短环的 RYGB 组中,肌少症的发生率从 13% 增加到 16%(差异在统计学上并不显著)。该组患者术后未发现明显的肌少症。根据生物电阻抗分析,如果患者有中度肌肉疏松症的迹象、患有 2 型糖尿病,以及老年人,建议进行 RYGB,并尽量减少吸收不良部分,增加限制性部分。
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引用次数: 0
Inpatient substitution approaches to medical care and their impact on the dynamics of the prevalence of varicose veins 住院替代医疗方法及其对静脉曲张流行动态的影响
Pub Date : 2023-11-30 DOI: 10.21518/akh2023-037
M. P. Potapov
Introduction. The conducted epidemiological studies show a significant socio-economic burden borne by modern society due to the high prevalence of varicose veins of the lower extremities among the able-bodied population of developed countries. Aim. Assessment ofthe influence ofthe factor of widespread use of minimally invasive inpatient replacement technologies on the prevalence of varicose veins of the lower extremities in a large region of the Central Federal District of the Russian Federation under the conditions of transformation of approaches to the treatment of varicose veins of the lower extremities. Materials and methods. A retrospective study was conducted for 2011–2021 of statistical indicators of the work of medical organizations of the Yaroslavl region, namely: the total number of attached adult population, the dynamics of the number of attached population, the total number and dynamics of the number of patients with an established diagnosis of varicose veins of the lower extremities. Results and discussion. The total population weight of the sample in the Yaroslavl region for all periods of the study was 11 406 181 people. The fixed weighted average value of the prevalence of varicose veins of the lower extremities at the end of the year in the Yaroslavl region in the period 2011–2021, according to medical organizations providing medical care on a territorial-precinct basis, was 0.784% (CI: 0.779–0.789). At the same time, in 2011–2012 and 2018–2019, the frequency of varicose veins of the lower extremities event was higher than the average value, in 2013–2016 and 2020–2021. Conclusion. It has been established that over the past decade there has been an annual decrease in the prevalence of varicose veins of the lower extremities in the region. At the same time, there was an increase in the share of medical care provided to patients by non-governmental medical organizations. The latter in their activities are focused on hospital-substituting technologies in the treatment of this disease.
导言。流行病学研究表明,在发达国家的健全人群中,下肢静脉曲张的发病率很高,给现代社会带来了沉重的社会经济负担。目的是在下肢静脉曲张治疗方法转型的条件下,评估微创住院置换技术的广泛应用对俄罗斯联邦中央联邦区这一大型地区下肢静脉曲张发病率的影响。材料和方法对雅罗斯拉夫尔地区医疗机构 2011-2021 年的工作统计指标进行了回顾性研究,即:附属成年人口总数、附属人口数量动态、确诊为下肢静脉曲张的患者总数和动态。结果与讨论研究期间,雅罗斯拉夫尔地区样本人口总数为 11 406 181 人。根据以地区为单位提供医疗服务的医疗机构提供的数据,2011-2021 年雅罗斯拉夫尔地区下肢静脉曲张发病率的固定加权平均值为 0.784%(CI:0.779-0.789)。同时,在 2011-2012 年和 2018-2019 年,下肢静脉曲张事件的发生频率高于 2013-2016 年和 2020-2021 年的平均值。结论是可以确定的是,在过去十年中,该地区下肢静脉曲张的发病率逐年下降。与此同时,非政府医疗组织为患者提供的医疗服务份额有所增加。非政府医疗组织的活动重点是在治疗这种疾病方面采用医院替代技术。
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Ambulatornaya khirurgiya = Ambulatory Surgery (Russia)
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