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Evaluation of the relationship between MRI and electrodiagnostic tests in acute traumatic spinal cord injury 急性外伤性脊髓损伤MRI与电诊断试验关系的评价
Q4 Medicine Pub Date : 2023-11-01 DOI: 10.5339/jemtac.2023.31
Roop Singh, Vijay Singh Meena, Jitendra Wadhwani, Rajesh Kumar Rohilla, Kiranpreet Kaur, Svareen Kaur
Purpose: Neuroimaging and electrodiagnostic studies are used to evaluate the changes in the spinal cord after trauma, both for clinical and research purposes. The aim of the present study was to find a correlation between the MRI and electrodiagnostic testing for acute traumatic spinal cord injury (SCI) over different points in time. Methods: Thirty-five patients with acute SCI presenting within 48 h of injury and completing a minimum of 6 months of regular follow-up comprised the study population. Patients were examined clinically for neurological involvement as per international guidelines. Magnetic resonance imaging (MRI) spine and electrodiagnostic testing of both lower limbs [two motor (tibial and peroneal) and one sensory (sural) nerve] and five muscles (Iliopsoas, Vastus medialis, Tibialis anterior, Gastrocnemius, and Extensor hallucis longus (EHL)] were done at admission, 3 and 6 months. Results: Quantitative MRI parameters [maximum spinal cord compression (MSCC), maximum canal compromise (MCC), and lesion length (LL)] showed a significant correlation to motor nerve conduction velocity and sensory nerve conduction velocity at all points in time. Electromyography of tested muscles at admission showed a significant correlation (Spearman’s correlation test) with MRI quantitative parameters (−0.818 to −0.510); stenosis (−0.564 to −0.347) except right EHL for peak to peak amplitude; and disk herniation (−0.427 to −0.339) except tibialis anterior for recruitment of motor unit potential (MUP) and iliopsoas, right gastrocnemius, and EHL for peak to peak amplitude. This correlation remained significant even at 3 and 6 months post-acute SCI. Conclusion: The quantitative MRI parameters, along with a few of the qualitative parameters, show a significant correlation with electrodiagnostic features at different points in acute traumatic SCI.
目的:神经影像学和电诊断研究用于评估创伤后脊髓的变化,用于临床和研究目的。本研究的目的是发现MRI和电诊断测试在不同时间点上对急性创伤性脊髓损伤(SCI)的相关性。方法:35例急性脊髓损伤患者在损伤后48小时内出现,并完成至少6个月的定期随访,构成研究人群。根据国际指南对患者进行临床神经系统检查。在入院时、3个月和6个月分别对双下肢[两条运动神经(胫腓神经)和一条感觉神经(腓肠神经)]和五块肌肉(髂腰肌、股内侧肌、胫前肌、腓肠肌和拇长伸肌(EHL))进行脊柱磁共振成像(MRI)和电诊断检查。结果:定量MRI参数[最大脊髓受压(MSCC)、最大椎管受累(MCC)和病变长度(LL)]在各时间点与运动神经传导速度和感觉神经传导速度有显著相关性。入院时被测肌肉的肌电图显示与MRI定量参数有显著相关性(Spearman相关检验)(- 0.818 ~ - 0.510);狭窄(- 0.564 ~ - 0.347),但右侧EHL峰到峰振幅除外;和椎间盘突出(- 0.427至- 0.339),除了胫骨前肌的运动单位电位(MUP)和髂腰肌、右腓肠肌和EHL的峰至峰振幅的增加。即使在急性脊髓损伤后3和6个月,这种相关性仍然显著。结论:MRI定量参数及部分定性参数与急性创伤性脊髓损伤不同时点的电诊断特征有显著相关性。
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引用次数: 0
Empathy as an essential component in the practice of medicine 同理心是医学实践的重要组成部分
Q4 Medicine Pub Date : 2023-11-01 DOI: 10.5339/jemtac.2023.28
Mozhdeh Delzendeh, Mehrdad Nazarieh, Amin Beigzadeh
Effective communication regarding the physician-patient relationship and empathy in an emergency setting is paramount for optimal care. In this regard, teaching intangible skills such as empathy to medical students as part of the formal curriculum should be considered accordingly. Teaching and evaluating intangible skills are essential competencies to be fostered by any practicing doctor, and their insufficiency as required skills may lead to better patient outcomes and patient satisfaction. In this letter, our primary focus is on empathy as an essential component in medical education and its development in emergency settings.
有效的沟通关于医患关系和移情在紧急情况下是最重要的最佳护理。在这方面,应该相应地考虑将移情等无形技能作为正式课程的一部分教授给医学生。教学和评估无形技能是任何执业医生培养的基本能力,作为必要技能,他们的不足可能会导致更好的患者结果和患者满意度。在这封信中,我们的主要重点是移情作为医学教育及其在紧急情况下发展的重要组成部分。
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引用次数: 0
Self-reported functional status among spinal cord injury patients using the spinal cord independence measures III: Integrative literature review 使用脊髓独立性测量的脊髓损伤患者自我报告的功能状态III:综合文献综述
Q4 Medicine Pub Date : 2023-11-01 DOI: 10.5339/jemtac.2023.30
Salam Amin Nassar, Fadi Khraim, Daniel Forgave, Ahmed Hajaj
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引用次数: 0
Unstable angina due to extrinsic coronary compression secondary to a giantic pulmonary artery aneurysm: An uncommon etiology 巨大肺动脉动脉瘤继发的外源性冠状动脉压迫引起的不稳定型心绞痛:一种罕见的病因
Q4 Medicine Pub Date : 2023-10-22 DOI: 10.5339/jemtac.2023.37
Astudillo−Álvarez Gloria Monserrath, Sánchez−Amaya David Jacobo, Godìnez−Córdova Luis Benjamín, Zebadua−Torres Rodrigo
Pulmonary hypertension (PH) is characterized by remodeling of the pulmonary blood vessels, resulting in structural and functional changes. While dyspnea and angina are common symptoms associated with the disease, rarely do they might stem from atypical factors like compression of the coronary arteries. Hence, it is crucial to consider anatomical imaging studies when assessing these patients. Treatment decisions depend on several factors, including disease severity and concurrent medical conditions. In this case report, we present a patient with both PH and a sizable pulmonary artery (PAA), which significantly compressed the left main coronary artery (LMCA). Conservative management was pursued, leading to a successful outcome. The occurrence of angina due to PAA in PH patients, although rare, underscores the importance of conducting a comprehensive evaluation for an accurate diagnosis.
肺动脉高压(Pulmonary hypertension, PH)的特点是肺血管的重塑,导致结构和功能的改变。虽然呼吸困难和心绞痛是与该疾病相关的常见症状,但它们很少是由冠状动脉受压等非典型因素引起的。因此,在评估这些患者时,考虑解剖成像研究是至关重要的。治疗决定取决于几个因素,包括疾病严重程度和同时存在的医疗条件。在这个病例报告中,我们提出了一个患有PH和相当大的肺动脉(PAA)的患者,这明显压缩了左冠状动脉主干(LMCA)。采取保守管理,取得了成功的结果。PH患者中PAA引起心绞痛的发生虽然罕见,但强调了进行全面评估以准确诊断的重要性。
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引用次数: 0
Epidemiology of scorpion sting and snakebite cases in Qatar 2018–2022: A primary care-based study 卡塔尔2018-2022年蝎子蜇伤和蛇咬伤病例的流行病学:一项基于初级保健的研究
Q4 Medicine Pub Date : 2023-10-22 DOI: 10.5339/jemtac.2023.26
Mohamed Ghaith Al-Kuwari, Ahmad Haj Bakri, Mujeeb Chettiyam Kandy, Jeyaram Illiayraja Krishnan, Jazeel Abdulmajeed, Yousef Al-Abdulla
Background: Envenomation caused by snakebites and scorpion stings is a neglected disease responsible for significant morbidity and mortality. In Qatar, little information is available on the epidemiological aspects of snakebites and scorpion stings. This study describes the demographic and epidemiological characteristics of patients treated for scorpion stings or snakebites at Qatar’s Primary Health Care Corporation (PHCC). Methods: A retrospective data analysis was applied to investigate the number of scorpion stings and snakebites reported at the PHCC health centers between January 1, 2018, and December 31, 2022. The data were electronically extracted from the medical records of the registered population at PHCC. Results: 581 scorpion stings and 21 cases of snakebites were reported between January 1, 2018, and December 31, 2022. The highest number of scorpion stings reported in 2020 was 141 cases. The distribution of scorpion stings was higher among males than females, with rates of 86% and 14%, respectively, and the highest number of cases occurred in the age group of 19–39 years. Among the total cases, Bangladeshi and Qatari were the most affected, with a rate of 41% and 14%, respectively. The western region had the highest incidence of scorpion stings, at 7.47 per 10,000 persons. Conclusion: According to this research, the western region had the highest occurrence of scorpion stings cases, primarily among Bangladeshis and Qataris, particularly in the age group of 19–49 years. This study also found similar patterns in snakebite cases. Consequently, this study emphasizes the need for increased investment in antivenom and the training of healthcare professionals to address scorpion stings effectively.
背景:毒蛇咬伤和蝎子螫伤引起的中毒是一种被忽视的疾病,具有很高的发病率和死亡率。在卡塔尔,关于蛇咬伤和蝎子螫伤的流行病学方面的资料很少。本研究描述了卡塔尔初级卫生保健公司(PHCC)治疗蝎子蜇伤或蛇咬伤患者的人口统计学和流行病学特征。方法:回顾性分析2018年1月1日至2022年12月31日在PHCC卫生中心报告的蝎子蜇伤和蛇咬伤的数量。数据以电子方式从PHCC登记人口的医疗记录中提取。结果:2018年1月1日至2022年12月31日,共报告蝎子蜇伤581例,蛇咬伤21例。据报道,2020年蝎子蜇伤的最高数量为141起。蝎子蜇伤发生率男性高于女性,分别为86%和14%,其中19 ~ 39岁年龄组发生率最高。在所有病例中,孟加拉国和卡塔尔受影响最大,分别为41%和14%。西部地区蝎子蜇伤发生率最高,为7.47 /万人。结论:西部地区蝎子蜇伤病例发生率最高,以孟加拉人和卡塔尔人为主,以19 ~ 49岁年龄组居多。这项研究也在蛇咬伤病例中发现了类似的模式。因此,这项研究强调需要增加抗蛇毒血清的投资和医疗保健专业人员的培训,以有效地解决蝎子蜇伤。
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引用次数: 0
Manifestation of acute stroke symptoms as toxic effects after flonicamid/sulfoxaflor pesticide poisoning 氟硝胺/亚砜农药中毒后急性卒中症状的毒性反应表现
Q4 Medicine Pub Date : 2023-10-22 DOI: 10.5339/jemtac.2023.32
Haewon Jung, Woo Young Nho
Global concern has focused on reducing the potential hazards to public health from unintentional pesticide poisoning. As a result, notorious agents have been banned from the market, and new materials that maintain their effectiveness against harmful insects with low human toxicity have been developed. Despite the development of several recent agents targeting the nervous system of insects, their clinical effects on humans are rarely known. We report a novel human intoxication with a mixture of flonicamid and sulfoxaflor pesticides, which presented with acute stroke manifestations. An 83-year-old man presented to the emergency department (ED) in a confused mental state and with right-sided hemiparesis for 2 h prior to the visit. The primary evaluation targeted a new onset of hemorrhagic stroke. Clinical manifestations showed no definite interval change for 2 days, and the diagnosis of stroke was ruled out after previous radiologic results revealed the presence of a pre-existing lesion. After 3 days, the patient recovered with an alert mentality and appropriate orientation. The patient remembered that he took the package of pesticide but flatly denied the intentional intake of toxic agents. The patient was discharged 5 days after admission without any neurological deficits. We present the first report of human intoxication with flonicamid or sulfoxaflor. Although the total amount of ingestion was not high, the patient showed unique clinical manifestations of stroke. Physicians should be aware of particular toxic materials when a differential diagnosis of stroke is required. Further investigations should be performed to estimate and reveal human toxicity.
全球关注的重点是减少无意农药中毒对公众健康的潜在危害。因此,臭名昭著的药剂已经被禁止进入市场,并且已经开发出了新的材料,可以保持它们对有害昆虫的有效性,对人体的毒性很低。尽管最近开发了几种针对昆虫神经系统的药物,但它们对人类的临床效果却很少为人所知。我们报告了一个新的人类中毒与氟虫胺和亚砜农药的混合物,这是急性中风的表现。一名83岁男性以精神错乱和右侧偏瘫2小时就诊于急诊科(ED)。初步评估的目标是新发出血性中风。临床表现在2天内没有明确的间隔变化,先前的影像学结果显示存在先前存在的病变,因此排除了卒中的诊断。3天后,患者恢复了警惕的心态和适当的方向。病人记得他服用了农药,但断然否认故意服用了有毒物质。患者入院5天后出院,无任何神经功能障碍。我们提出的第一份报告,人类中毒与氟虫胺或砜氟。虽然摄入总量不高,但患者表现出独特的脑卒中临床表现。当需要对中风进行鉴别诊断时,医生应注意特定的有毒物质。应进行进一步的调查,以估计和揭示人体毒性。
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引用次数: 0
Risk factors and clinical presentation of traumatic cerebral hemorrhagic contusion in Sudanese patients at the National Center for Neurological Sciences, Khartoum, Sudan 苏丹喀土穆国家神经科学中心创伤性脑出血挫伤患者的危险因素和临床表现
Q4 Medicine Pub Date : 2023-10-22 DOI: 10.5339/jemtac.2023.27
Samah Abdelrahman Hassan Ibrahim
Background: Traumatic cerebral contusion is a major global health concern due to its association with poor clinical prognosis. The aim of this study is to determine the risk factors and clinical presentation of traumatic cerebral contusion in Sudan. Methods: A prospective cross- sectional observational hospital-based study was conducted in 90 patients with traumatic cerebral hemorrhagic contusion admitted to the National Center for Neurological Sciences (NCNS) over a period of six months. Results: The results show that most patients were male, age 25 to 44 years, 75.6% from rural areas, and 67.8 % from Afro-Asiatic linguistic affiliated tribes. The most common cause of traumatic brain hemorrhagic contusion was road traffic accidents (RTA) 68.9%, followed by assault 24.4%, and fall 6.7%. About 60% of the patients suffered a frontal lobe injury while 14.4% of the patients had multiple injury sites. Brain edema was observed in 22.2% of the patients. According to the Glasgow Coma Scale, 11.1% suffered severe, 30% moderate and 58.9% mild brain injury. Death rate was 8.9% Conclusion: In conclusion, male gender, age 25-44 years, rural residents and victims of RTA were the most common characteristics observed in patients with traumatic hemorrhagic brain contusion in Sudan. The study also observed that brain edema and anatomical site of hemorrhage were not associated with death while male gender and GCS were. Traumatic cerebral hemorrhagic contusion is a major public health issue in Sudan carrying significant socioeconomic effects.
背景:外伤性脑挫伤是一个主要的全球健康问题,因为它与不良的临床预后有关。本研究的目的是确定苏丹创伤性脑挫伤的危险因素和临床表现。方法:对美国国家神经科学中心(NCNS)收治的90例外伤性脑出血挫伤患者进行为期6个月的前瞻性横断面观察性医院研究。结果:患者以男性居多,年龄在25 ~ 44岁之间,75.6%的患者来自农村地区,67.8%的患者来自亚非语系附属部落。造成外伤性脑出血挫伤的最常见原因是道路交通事故(RTA),占68.9%,其次是殴打(24.4%)和跌倒(6.7%)。约60%的患者出现额叶损伤,14.4%的患者出现多处损伤。22.2%的患者出现脑水肿。根据格拉斯哥昏迷量表,11.1%为重度脑损伤,30%为中度脑损伤,58.9%为轻度脑损伤。结论:男性、25-44岁、农村居民和RTA受害者是苏丹外伤性出血性脑挫伤患者最常见的特征。研究还发现,脑水肿和出血解剖部位与死亡无关,而男性和GCS与死亡相关。创伤性脑出血挫伤是苏丹的一个重大公共卫生问题,具有重大的社会经济影响。
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引用次数: 0
Lower extremity injuries secondary to road traffic accidents in East Africa: A systematic review 东非道路交通事故致下肢损伤:系统综述
Q4 Medicine Pub Date : 2023-10-22 DOI: 10.5339/jemtac.2023.34
Steven Ayotte, Avi V. Dravid, Mattia A. Mahmoud, Keith D. Baldwin, Neil P. Sheth
Background: Road traffic accidents (RTAs) are a significant contributor to morbidity and mortality in East Africa. Lower extremity (LE) injuries are especially debilitating, negatively impacting quality of life and employment prospects. This systematic review characterizes the proportion of LE injuries due to RTAs in four members of the East African Community: Kenya, Rwanda, Tanzania, and Uganda. Methods: Embase, Medline, Web of Science, and PubMed were queried for studies from 2010 to 2022 providing information on lower extremity injuries caused by RTAs in the countries of interest. Proportions of RTA-related LE injuries were extracted from eligible papers. Study quality and bias were assessed using the framework for systematic reviews established by Zaza et al.1 Results: Seven studies met the eligibility criteria–four for Kenya, two for Uganda, and one for Tanzania; however, no eligible studies were found for Rwanda. The proportion of RTA-related injuries affecting the lower extremities ranged from 0.39 to 0.49. In patients presenting with LE injuries, RTAs were the most frequent cause, representing more than 70% of cases in the examined studies. Motorcycle accidents were not more likely to cause LE injuries, but they were the most significant contributor to the overall LE injury burden due to their prevalence. Conclusions: With urbanization and the increased adoption of low-cost motorcycles, RTAs will continue to pose a public health challenge. Investments in traffic enforcement and physical infrastructure will alleviate the risks to both motorists and pedestrians. In addition to primary prevention, there is a significant need for improvements in emergency care and surgical capacity.
背景:道路交通事故是东非发病率和死亡率的一个重要因素。下肢(LE)损伤尤其使人衰弱,对生活质量和就业前景产生负面影响。本系统综述分析了东非共同体四个成员国(肯尼亚、卢旺达、坦桑尼亚和乌干达)因rta导致的LE损伤比例。方法:对Embase、Medline、Web of Science和PubMed在2010年至2022年间的研究进行了查询,这些研究提供了相关国家由rta引起的下肢损伤的信息。从符合条件的论文中提取rta相关LE损伤的比例。使用Zaza等人建立的系统评价框架对研究质量和偏倚进行了评估。结果:7项研究符合资格标准——肯尼亚4项,乌干达2项,坦桑尼亚1项;但是,没有为卢旺达找到符合条件的研究。rta相关损伤影响下肢的比例为0.39 ~ 0.49。在LE损伤患者中,rta是最常见的原因,占研究中70%以上的病例。摩托车事故不太可能导致LE损伤,但由于其普遍性,它们是整体LE损伤负担的最重要贡献者。结论:随着城市化和低成本摩托车的普及,rta将继续对公共卫生构成挑战。对交通执法和实体基础设施的投资将减轻对驾车者和行人的风险。除了初级预防外,迫切需要改进急诊护理和外科手术能力。
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引用次数: 0
The art of healing in the era of emerging technologies: Back to the fundamentals of clinical medicine 新兴技术时代的治疗艺术:回到临床医学的基础
Q4 Medicine Pub Date : 2023-09-23 DOI: 10.5339/jemtac.2023.13
Ruben Peralta
QScience.com is the innovative and collaborative, peer-reviewed, online publishing platform from Hamad bin Khalifa University Press (HBKU Press). It offers a fast and transparent Open Access scholarly publishing process, which is centered on the author, bringing their research to a global audience.
QScience.com是哈马德·本·哈利法大学出版社(HBKU出版社)的创新、协作、同行评议的在线出版平台。它提供了一个快速透明的开放获取学术出版过程,以作者为中心,将他们的研究成果带给全球受众。
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引用次数: 0
Regulatory Role of Human Neutrophil Peptides (HNP1-3) on Interleukin-6 Production in Early Childhood Caries 人中性粒细胞肽(HNP1-3)对早期儿童龋齿中白细胞介素-6产生的调节作用
Q4 Medicine Pub Date : 2023-07-31 DOI: 10.5339/jemtac.2023.midc.11
Sarah Jamal Kareem, B. Al-Ghurabi
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引用次数: 0
期刊
Journal of Emergency Medicine, Trauma and Acute Care
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