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Integrating augmented intelligence and artificial intelligence into primary healthcare. 将增强智能和人工智能集成到初级医疗保健中。
Q3 Nursing Pub Date : 2025-10-07 eCollection Date: 2025-01-01 DOI: 10.51866/lte.25.01
S Kaviyarasan Sailin Stalin
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引用次数: 0
Prevalence and associated factors of high-level diabetes-related distress among patients with type 2 diabetes mellitus in northern Malaysian primary care settings: A cross-sectional study. 马来西亚北部初级保健机构中2型糖尿病患者高水平糖尿病相关窘迫的患病率及相关因素:一项横断面研究
Q3 Nursing Pub Date : 2025-10-05 eCollection Date: 2025-01-01 DOI: 10.51866/oa.796
Peng Yit Tan, Azmilumur Mahfuzah, Kupusamy Gaayatiri, Darshini Latsmanan Rhena, Govindasamy Sangeetha, Mohamed Syarif Mohamed Yassin, Noorhida Baharudin

Introduction: Diabetes-related distress (DRD) affects disease control and quality of life. This study aimed to determine the prevalence of high-level DRD, compare the prevalence according to diabetes complications and identify the associated sociodemographic and clinical factors.

Methods: This cross-sectional study included 198 participants from three primary care clinics in northern Malaysia from 1 May 2023 to 31 July 2023. DRD was measured using the 17-Item Diabetes Distress Scale, with a score of >3 indicating high-level distress. Multiple logistic regression was used to assess the association between the sociodemographic and clinical characteristics and DRD.

Results: The prevalence of high-level DRD was 13.6%. The prevalence was significantly higher among the patients without nephropathy (17.2%) than among those with nephropathy (3.8%) (P=0.014) but did not significantly differ among those with other complications. Those who attended the clinics independently were less likely to be highly distressed than those using public transportation or sent by others (adjusted odds ratio [aOR]=0.31, 95% confidence interval [CI]=0.10-0.99, P=0.048). The participants who were obese (aOR=2.96, 95% CI=1.08-8.08, P=0.034) had higher odds of having high-level DRD than those who were not, while those who had nephropathy (aOR=0.11, 95% CI=0.02-0.58, P=0.010) had lower odds of having high-level DRD than those who did not.

Conclusion: The overall prevalence of high-level DRD is relatively low but significantly higher among individuals without nephropathy. 0besity, lack of transportation and the absence of nephropathy are positively associated with high-level DRD and should therefore be a focus of psychological support and intervention.

糖尿病相关焦虑(DRD)影响疾病控制和生活质量。本研究旨在确定高水平DRD的患病率,根据糖尿病并发症比较患病率,并确定相关的社会人口统计学和临床因素。方法:这项横断面研究包括来自马来西亚北部三家初级保健诊所的198名参与者,时间为2023年5月1日至2023年7月31日。DRD采用17项糖尿病困扰量表(Diabetes Distress Scale)进行测量,得分为bbbb3表示患者的困扰程度较高。采用多元逻辑回归来评估社会人口学和临床特征与DRD之间的关系。结果:高水平DRD患病率为13.6%。无肾病患者的患病率(17.2%)明显高于有肾病患者(3.8%)(P=0.014),但在有其他并发症的患者中差异无统计学意义。与乘坐公共交通工具或由他人送医的患者相比,独立就诊的患者更不容易感到极度痛苦(校正优势比[aOR]=0.31, 95%可信区间[CI]=0.10-0.99, P=0.048)。肥胖的参与者(aOR=2.96, 95% CI=1.08-8.08, P=0.034)发生高水平DRD的几率高于非肥胖的参与者,而患有肾病的参与者(aOR=0.11, 95% CI=0.02-0.58, P=0.010)发生高水平DRD的几率低于非肥胖的参与者。结论:高水平DRD的总体患病率相对较低,但在无肾病的个体中明显较高。肥胖、缺乏交通和无肾病与高水平DRD呈正相关,因此应成为心理支持和干预的重点。
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引用次数: 0
Hypothalamic amenorrhoea as an extraintestinal manifestation of Crohn's disease: A case report. 下丘脑闭经作为克罗恩病的肠外表现:1例报告。
Q3 Nursing Pub Date : 2025-10-01 eCollection Date: 2025-01-01 DOI: 10.51866/cr.937
Ibrahim Adibah, Omar Ahmad Akram, Nageshar Ashna, Vikiraman Tamileswari

Crohn's disease (CD), a chronic inflammatory bowel condition, although rare in Malaysia, can present with atypical systemic features, including reproductive dysfUnction. We report the case of a 31-year-old woman referred for secondary amenorrhoea and presumed endometriosis, later diagnosed with CD following worsening gastrointestinal symptoms and significant weight loss. Hormonal evaluation revealed hypothalamic-pituitary axis suppression secondary to malnutrition and systemic inflammation. Treatment with corticosteroids and nutritional rehabilitation led to weight gain and resumption of menses within 3 months. This case highlights the importance of recognising functional hypothalamic amenorrhoea as a reversible consequence of chronic illness and nutritional deficiency. It also underscores how systemic diseases such as CD may mimic gynaecological conditions, potentially delaying accurate diagnosis. Early multidisciplinary collaboration is essential in evaluating menstrual disturbances with overlapping gastrointestinal symptoms, especially in regions where inflammatory bowel disease remains uncommon.

克罗恩病(CD)是一种慢性炎症性肠病,虽然在马来西亚很少见,但可表现出非典型的全身特征,包括生殖功能障碍。我们报告一例31岁的女性继发性闭经和子宫内膜异位症,后来诊断为乳糜泻胃肠道症状恶化和体重明显下降。激素评估显示继发于营养不良和全身性炎症的下丘脑-垂体轴抑制。糖皮质激素和营养康复治疗导致体重增加,并在3个月内恢复月经。本病例强调认识功能性下丘脑闭经是慢性疾病和营养缺乏的可逆后果的重要性。它还强调了像乳糜泻这样的全身性疾病是如何模仿妇科疾病的,这可能会延迟准确的诊断。早期多学科合作对于评估具有重叠胃肠道症状的月经紊乱至关重要,特别是在炎症性肠病仍然不常见的地区。
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引用次数: 0
24-day-old newborn with tinea capitis: A case report. 24日龄新生儿头癣1例。
Q3 Nursing Pub Date : 2025-09-16 eCollection Date: 2025-01-01 DOI: 10.51866/cr.902
Fa'iza Abdullah, Cm Nor Azmi Hani Azmina, Che Abdul Rahim Abdul Rahman

Tinea capitis is a common childhood fungal infection that is extremely rare in newborns, with limited data available. Its clinical presentation may closely resemble that of other dermatological conditions such as seborrheic dermatitis, neonatal lupus erythematosus and congenital syphilis. It is essential to make a definite diagnosis, as tinea capitis treatment requires systemic antifungal therapy. However, successful topical monotherapies have been reported. We report a rare case of neonatal tinea capitis diagnosed in a 24-day-old newborn, presenting with multiple scaly plaques on the scalp, discussing the diagnostic criteria, predisposing factors, appropriate treatment and preventive measures. The patient was treated with topical antifungal therapy, resulting in complete resolution within a week and no recurrence at the 2-year follow-up.

头癣是一种常见的儿童真菌感染,在新生儿中极为罕见,数据有限。它的临床表现可能与其他皮肤病如脂溢性皮炎、新生儿红斑狼疮和先天性梅毒非常相似。必须作出明确的诊断,因为头癣的治疗需要全身抗真菌治疗。然而,已有报道成功的局部单一疗法。我们报告一个罕见的病例新生儿头癣诊断在24天的新生儿,表现为多个鳞状斑块在头皮上,讨论诊断标准,易感因素,适当的治疗和预防措施。患者接受局部抗真菌治疗,一周内完全消退,2年随访无复发。
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引用次数: 0
Never lose hope, regardless of how gloomy it gets - Fuji-san. 永远不要失去希望,不管它变得多么黯淡。
Q3 Nursing Pub Date : 2025-09-11 eCollection Date: 2025-01-01 DOI: 10.51866/mol.981
Imran Ahmad, Ruzilawati Abu Bakar
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引用次数: 0
Association of symptoms and comorbidities with hospitalization among patients infected with coronavirus disease : A cross-sectional study among users of Universitas Sumatera Utara's COVID-19 Telemedicine. 冠状病毒感染患者的症状和合并症与住院的关系:苏门答腊北方大学COVID-19远程医疗用户的横断面研究
Q3 Nursing Pub Date : 2025-09-11 eCollection Date: 2025-01-01 DOI: 10.51866/oa.329
Albert Tanaka, Isti Ilmiati Fujiati

Introduction: Coronavirus disease (COVID-19) is a highly contagious disease caused by severe acute respiratory syndrome coronavirus 2 and was declared by the World Health Organization as a pandemic on 11 March 2020. However, COVID-19 will continue to occur in the future. Therefore, this research aimed to determine the factors that affect the risk of hospitalisation of patients infected with COVID-19 so that preventive measures can be taken promptly.

Methods: This study adopted a descriptive, analytic, cross-sectional research design. The sample included the people of North Sumatra who used Universitas Sumatera Utara's COVID-19 Telemedicine and met the research criteria. The data were analysed using the chi-square test, with odds ratios (ORs) calculated.

Results: Among the clinical symptoms of the patients, runny nose (OR=10.9), sore throat (OR=23.5), muscle pain (OR=24.3), headache (OR=33.7), diarrhoea (OR=7.7), nausea (OR=10.6), vomiting (OR=4.4), ageusia (OR=6.3) and anosmia (OR=5.5) were more commonly associated with an increased risk of hospitalisation. Among the comorbidities, hypertension (OR=2.5) and diabetes (OR=4.9) increased the risk of hospitalisation.

Conclusion: Runny nose, sore throat, muscle pain, headache, diarrhoea, nausea, vomiting, ageusia, anosmia, diabetes and hypertension are associated with an increased risk of hospitalisation among patients with COVID-19.

简介:冠状病毒病(COVID-19)是由严重急性呼吸系统综合征冠状病毒2引起的高度传染性疾病,世界卫生组织于2020年3月11日宣布为大流行。然而,COVID-19将在未来继续发生。因此,本研究旨在确定影响COVID-19患者住院风险的因素,以便及时采取预防措施。方法:本研究采用描述性、分析性、横断面研究设计。样本包括使用北苏门答腊大学COVID-19远程医疗并符合研究标准的北苏门答腊人。采用卡方检验对数据进行分析,并计算优势比(or)。结果:在患者的临床症状中,流鼻涕(OR=10.9)、喉咙痛(OR=23.5)、肌肉痛(OR=24.3)、头痛(OR=33.7)、腹泻(OR=7.7)、恶心(OR=10.6)、呕吐(OR=4.4)、衰老(OR=6.3)和嗅觉丧失(OR=5.5)与住院风险增加的相关性更为常见。在合并症中,高血压(OR=2.5)和糖尿病(OR=4.9)增加了住院的风险。结论:流鼻涕、喉咙痛、肌肉痛、头痛、腹泻、恶心、呕吐、老年痴呆、嗅觉丧失、糖尿病和高血压与COVID-19患者住院风险增加有关。
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引用次数: 0
Prevalence and risk factors of preterm birth among pregnant adolescents in Kuala Lumpur: A cross-sectional study. 吉隆坡怀孕青少年早产的患病率和危险因素:一项横断面研究。
Q3 Nursing Pub Date : 2025-09-11 eCollection Date: 2025-01-01 DOI: 10.51866/oa.711
Nur Aznida Abu Bakar, Dalila Roslan, Nik Nairan Abdullah, Musbahiyah Mat Zainal, Pillai Simon Puvanese Rebecca

Introduction: Adolescent pregnancies are often associated with a higher risk of adverse outcomes, including preterm birth, which may lead to severe physiological and psychological health impacts on both mothers and children. Despite the acknowledged risks, there is a knowledge gap regarding the risk factors of preterm birth among pregnant adolescents. This study aimed to determine the prevalence and associated sociodemographic, maternal, intrapartum and neonatal factors of preterm birth among pregnant adolescents in Kuala Lumpur.

Methods: A cross-sectional study was conducted in Kuala Lumpur, Malaysia, from March to June 2024. Samples were selected using simple random sampling from the Wilayah Persekutuan Kuala Lumpur and Putrajaya Department of Health pregnant adolescents' line listing from 2019 to 2023. Simple and multiple logistic regression analyses were used to determine the factors associated with preterm birth.

Results: A total of 175 pregnant adolescents were included in the study. The prevalence of preterm birth was 16%. Anaemia at booking (adjusted odds ratio [aOR]: 7.8; 95% confidence interval [CI]: 2.53, 23.997), history of preterm birth (aOR: 11.654; 95% CI: 1.517, 89.498), history of smoking (aOR: 6.89; 95% CI: 1.397, 34.002) and low birth weight (aOR: 12.503; 95% CI: 3.858, 40.522) were significantly associated with preterm birth.

Conclusion: Targeted interventions to address anaemia, history of smoking, previous history of preterm births and low birth weight babies in adolescent pregnancies are crucial to reduce the incidence of preterm birth and improve maternal and infant health outcomes in this population among adolescents.

导言:少女怀孕往往与包括早产在内的不良后果风险较高有关,这可能对母亲和儿童造成严重的生理和心理健康影响。尽管存在公认的风险,但对怀孕少女早产的风险因素仍存在知识差距。本研究旨在确定吉隆坡怀孕青少年中早产的患病率和相关的社会人口学、产妇、产时和新生儿因素。方法:于2024年3月至6月在马来西亚吉隆坡进行横断面研究。样本采用简单随机抽样的方法,从吉隆坡和布城卫生局2019年至2023年怀孕少女名单中选择。使用简单和多元逻辑回归分析来确定与早产相关的因素。结果:本研究共纳入175名怀孕少女。早产率为16%。产前贫血(校正优势比[aOR]: 7.8; 95%可信区间[CI]: 2.53, 23.997)、早产史(aOR: 11.654; 95% CI: 1.517, 89.498)、吸烟史(aOR: 6.89; 95% CI: 1.397, 34.002)和低出生体重(aOR: 12.503; 95% CI: 3.858, 40.522)与早产显著相关。结论:针对青少年妊娠中贫血、吸烟史、早产史和低出生体重儿的针对性干预措施对于降低该人群的早产发生率和改善母婴健康结局至关重要。
{"title":"Prevalence and risk factors of preterm birth among pregnant adolescents in Kuala Lumpur: A cross-sectional study.","authors":"Nur Aznida Abu Bakar, Dalila Roslan, Nik Nairan Abdullah, Musbahiyah Mat Zainal, Pillai Simon Puvanese Rebecca","doi":"10.51866/oa.711","DOIUrl":"10.51866/oa.711","url":null,"abstract":"<p><strong>Introduction: </strong>Adolescent pregnancies are often associated with a higher risk of adverse outcomes, including preterm birth, which may lead to severe physiological and psychological health impacts on both mothers and children. Despite the acknowledged risks, there is a knowledge gap regarding the risk factors of preterm birth among pregnant adolescents. This study aimed to determine the prevalence and associated sociodemographic, maternal, intrapartum and neonatal factors of preterm birth among pregnant adolescents in Kuala Lumpur.</p><p><strong>Methods: </strong>A cross-sectional study was conducted in Kuala Lumpur, Malaysia, from March to June 2024. Samples were selected using simple random sampling from the Wilayah Persekutuan Kuala Lumpur and Putrajaya Department of Health pregnant adolescents' line listing from 2019 to 2023. Simple and multiple logistic regression analyses were used to determine the factors associated with preterm birth.</p><p><strong>Results: </strong>A total of 175 pregnant adolescents were included in the study. The prevalence of preterm birth was 16%. Anaemia at booking (adjusted odds ratio [aOR]: 7.8; 95% confidence interval [CI]: 2.53, 23.997), history of preterm birth (aOR: 11.654; 95% CI: 1.517, 89.498), history of smoking (aOR: 6.89; 95% CI: 1.397, 34.002) and low birth weight (aOR: 12.503; 95% CI: 3.858, 40.522) were significantly associated with preterm birth.</p><p><strong>Conclusion: </strong>Targeted interventions to address anaemia, history of smoking, previous history of preterm births and low birth weight babies in adolescent pregnancies are crucial to reduce the incidence of preterm birth and improve maternal and infant health outcomes in this population among adolescents.</p>","PeriodicalId":40017,"journal":{"name":"Malaysian Family Physician","volume":"20 ","pages":"60"},"PeriodicalIF":0.0,"publicationDate":"2025-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12510770/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145281478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Factors associated with home blood pressure monitoring practices among patients with hypertension in Putrajaya, Malaysia: A cross-sectional study. 马来西亚布城高血压患者家庭血压监测相关因素:一项横断面研究。
Q3 Nursing Pub Date : 2025-09-11 eCollection Date: 2025-01-01 DOI: 10.51866/oa.889
Luqman Melissha, Siew Mooi Ching, Mohamad Fadzilah, Hanum Mohd Yusof Hazira

Introduction: This study primarily aimed to determine the factors associated with home blood pressure monitoring (HBPM) practices among patients with hypertension in Putrajaya, Malaysia.

Methods: A cross-sectional study was conducted among patients with hypertension aged 18 years and above in a government health clinic in Putrajaya. An adopted and validated questionnaire on the knowledge, attitude and practice of HBPM was utilised. A total of 338 patients with hypertension were recruited.

Results: The median age of the participants was 52 years. Approximately 95.3%, 87.3%, 61.2%, 54.4% and 49.4% were Malay, were married, completed tertiary education, were men and were government servants, respectively. The prevalence of good HBPM knowledge, good attitude towards HBPM and HBPM practice among the participants was 79.0%, 57.1% and 81.7%, respectively. Having medical insurance (adjusted odds ratio [aOR]: 3.05, 95% confidence interval (CI): 1.47- 6.29, P=0.003), having diabetes mellitus (DM) (aOR: 4.58, 95% CI: 2.47-8.49, P<0.01), staying with household members (aOR: 2.95, 95% CI: 1.07-8.10, P=0.036), being a non-smoker (aOR: 3.72, 95% CI: 1.41-9.80, P=0.008) and engaging in physical activity (aOR: 2.47, 95% CI: 1.314.65, P=0.005) showed significant associations with HBPM practice.

Conclusion: The knowledge and practice of HBPM among patients with hypertension in Putrajaya, Malaysia, were excellent. The significant associated factors of HBPM practice were having medical insurance, having DM, staying with household members, being a non-smoker and being physically active. This study should be extended to the whole nation to obtain a true reflection of HBPM practice among Malaysians.

本研究主要旨在确定马来西亚布城高血压患者家庭血压监测(HBPM)实践的相关因素。方法:对布城一家政府卫生诊所18岁及以上的高血压患者进行横断面研究。采用一份经过验证的问卷,对HBPM的知识、态度和实践进行调查。总共招募了338名高血压患者。结果:参与者的中位年龄为52岁。大约95.3%、87.3%、61.2%、54.4%和49.4%分别是马来人、已婚、完成高等教育、男性和政府公务员。受访者对HBPM有良好的知识、良好的态度和实施HBPM的比例分别为79.0%、57.1%和81.7%。有医疗保险(调整优势比[aOR]: 3.05, 95%可信区间(CI): 1.47 ~ 6.29, P=0.003),有糖尿病(DM) (aOR: 4.58, 95% CI: 2.47 ~ 8.49, P)结论:马来西亚布城高血压患者HBPM知识和实践情况良好。HBPM实践的显著相关因素是有医疗保险、有糖尿病、与家庭成员住在一起、不吸烟和体育锻炼。这项研究应该扩展到全国,以获得马来西亚人HBPM实践的真实反映。
{"title":"Factors associated with home blood pressure monitoring practices among patients with hypertension in Putrajaya, Malaysia: A cross-sectional study.","authors":"Luqman Melissha, Siew Mooi Ching, Mohamad Fadzilah, Hanum Mohd Yusof Hazira","doi":"10.51866/oa.889","DOIUrl":"10.51866/oa.889","url":null,"abstract":"<p><strong>Introduction: </strong>This study primarily aimed to determine the factors associated with home blood pressure monitoring (HBPM) practices among patients with hypertension in Putrajaya, Malaysia.</p><p><strong>Methods: </strong>A cross-sectional study was conducted among patients with hypertension aged 18 years and above in a government health clinic in Putrajaya. An adopted and validated questionnaire on the knowledge, attitude and practice of HBPM was utilised. A total of 338 patients with hypertension were recruited.</p><p><strong>Results: </strong>The median age of the participants was 52 years. Approximately 95.3%, 87.3%, 61.2%, 54.4% and 49.4% were Malay, were married, completed tertiary education, were men and were government servants, respectively. The prevalence of good HBPM knowledge, good attitude towards HBPM and HBPM practice among the participants was 79.0%, 57.1% and 81.7%, respectively. Having medical insurance (adjusted odds ratio [aOR]: 3.05, 95% confidence interval (CI): 1.47- 6.29, P=0.003), having diabetes mellitus (DM) (aOR: 4.58, 95% CI: 2.47-8.49, P<0.01), staying with household members (aOR: 2.95, 95% CI: 1.07-8.10, P=0.036), being a non-smoker (aOR: 3.72, 95% CI: 1.41-9.80, P=0.008) and engaging in physical activity (aOR: 2.47, 95% CI: 1.314.65, P=0.005) showed significant associations with HBPM practice.</p><p><strong>Conclusion: </strong>The knowledge and practice of HBPM among patients with hypertension in Putrajaya, Malaysia, were excellent. The significant associated factors of HBPM practice were having medical insurance, having DM, staying with household members, being a non-smoker and being physically active. This study should be extended to the whole nation to obtain a true reflection of HBPM practice among Malaysians.</p>","PeriodicalId":40017,"journal":{"name":"Malaysian Family Physician","volume":"20 ","pages":"61"},"PeriodicalIF":0.0,"publicationDate":"2025-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12510775/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145281443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reply to: 'Postgraduate family medicine training in Southeast Asia' by Wattanapisit et al. (2025). 回复:Wattanapisit等人的“东南亚研究生家庭医学培训”(2025)。
Q3 Nursing Pub Date : 2025-09-02 eCollection Date: 2025-01-01 DOI: 10.51866/lte.979
Schawanya Kaewpitoon Rattanapitoon, Chutharat Thanchonnang, Nathkapach Kaewpitoon Rattanapitoon
{"title":"Reply to: 'Postgraduate family medicine training in Southeast Asia' by Wattanapisit et al. (2025).","authors":"Schawanya Kaewpitoon Rattanapitoon, Chutharat Thanchonnang, Nathkapach Kaewpitoon Rattanapitoon","doi":"10.51866/lte.979","DOIUrl":"10.51866/lte.979","url":null,"abstract":"","PeriodicalId":40017,"journal":{"name":"Malaysian Family Physician","volume":"20 ","pages":"63"},"PeriodicalIF":0.0,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12510771/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145281450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Glycogenic hepatopathy - An underrecognised cause of transaminitis in primary care settings: A case report. 糖原性肝病-初级保健机构中未被充分认识的转氨炎病因:一个病例报告。
Q3 Nursing Pub Date : 2025-08-27 eCollection Date: 2025-01-01 DOI: 10.51866/cr.926
Zainul Abidin Nordiyana, Ying Ying Ng, Zakaria Rosnani, Samsuddin Noor Aellmas

Glycogenic hepatopathy (GH) is a rare but reversible hepatic condition associated with poorly controlled type 1 diabetes mellitus (T1DM). It results from excessive glycogen accumulation in hepatocytes, leading to hepatomegaly and elevated liver enzyme levels. We report the case of a 28-year-old man with T1DM who presented to a primary care clinic with persistent transaminitis despite discontinuation of potential hepatotoxic agents. Extensive investigations were conducted to exclude common liver pathologies, all of which returned negative. His condition improved following the intensification of insulin therapy and improvement of glycaemic control. This case underscores the role of family physicians in recognising GH as a differential diagnosis in patients with diabetes mellitus with unexplained liver enzyme abnormalities. It also highlights the importance of timely interventions to prevent unnecessary invasive investigations. Early recognition and appropriate glycaemic management in primary care can reverse the condition and minimise the need for extensive testing.

糖原性肝病(GH)是一种罕见但可逆的肝病,与控制不良的1型糖尿病(T1DM)相关。它是由肝细胞中过量的糖原积累引起的,导致肝肿大和肝酶水平升高。我们报告一例28岁的男性T1DM患者,尽管停用了潜在的肝毒性药物,但仍以持续性转氨炎就诊于初级保健诊所。进行了广泛的调查,以排除常见的肝脏病变,所有结果均为阴性。随着胰岛素治疗的加强和血糖控制的改善,病情有所改善。本病例强调了家庭医生在糖尿病伴不明原因肝酶异常的患者中将GH作为鉴别诊断的作用。它还强调了及时干预以防止不必要的侵入性调查的重要性。在初级保健中及早发现和适当的血糖管理可以扭转病情,并尽量减少广泛检测的需要。
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引用次数: 0
期刊
Malaysian Family Physician
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