Pub Date : 2025-07-29eCollection Date: 2025-01-01DOI: 10.51866/cr.877
Tamring Sarinah, Mat Nawi Zanaridah, Nik Yusof Fuad Nik Farah, Joon Hi Tham, Mohamad Setia Awang Shahrunizam
This is a case report of a middle-aged man who presented with chronic unilateral lower limb swelling and a mass on the same side. Several important differential diagnoses were considered. Lymphatic filariasis was included in the differential diagnoses due to a history of travel to a district endemic with filariasis in Sabah. A final diagnosis of soft tissue sarcoma was provisionally made based on the magnetic resonance imaging findings and confirmed by histopathological examination as pleomorphic dermal sarcoma. Both conditions are unusual but important causes in primary care due to their association with poor morbidity and risk of mortality. Patient management should involve a multidisciplinary team, including primary care, public health, radiology, pathology and orthopaedics.
{"title":"Lymphoedema - Filariasis or soft tissue sarcoma? A case report.","authors":"Tamring Sarinah, Mat Nawi Zanaridah, Nik Yusof Fuad Nik Farah, Joon Hi Tham, Mohamad Setia Awang Shahrunizam","doi":"10.51866/cr.877","DOIUrl":"10.51866/cr.877","url":null,"abstract":"<p><p>This is a case report of a middle-aged man who presented with chronic unilateral lower limb swelling and a mass on the same side. Several important differential diagnoses were considered. Lymphatic filariasis was included in the differential diagnoses due to a history of travel to a district endemic with filariasis in Sabah. A final diagnosis of soft tissue sarcoma was provisionally made based on the magnetic resonance imaging findings and confirmed by histopathological examination as pleomorphic dermal sarcoma. Both conditions are unusual but important causes in primary care due to their association with poor morbidity and risk of mortality. Patient management should involve a multidisciplinary team, including primary care, public health, radiology, pathology and orthopaedics.</p>","PeriodicalId":40017,"journal":{"name":"Malaysian Family Physician","volume":"20 ","pages":"51"},"PeriodicalIF":0.0,"publicationDate":"2025-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12334323/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144817847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: Sexual health is integral to quality of life, and female sexual dysfunction (FSD) is a significant public health concern recognised by the World Health Organization. Its prevalence is rising globally, with limited data among primary care practitioners (PCPs). Multifactorial issues such as high work burden in PCPs, coupled with low help-seeking behaviours, contribute to the likelihood of FSD and poor quality of life. This study aimed to determine the prevalence and associated factors of FSD among PCPs in Malaysia.
Methods: This cross-sectional study was conducted using a self-administered online questionnaire for 6 months duration in Malaysia. Sociodemographic, marital and clinical data were collected, and two validated questionnaires namely the Malay Version of the Female Sexual Function Index (MVFSFI) and the Depression, Anxiety and Stress Scale (DASS-21) were utilised. Data analysis included descriptive statistics and logistic regression.
Results: The study included 382 participants. The prevalence of FSD was 14.7% (95% confidence interval [CI] : 11.1, 18.2) among the participants, and the most affected domain was desire disorder (25.4%). Significant associations were observed between sexual activity two or fewer times per month (adjusted odds ratio [aOR]: 4.880; 95% CI: 2.522, 9.442; P<0.001), depression (aOR: 3.450; 95% CI: 1.653, 7.204; P<0.001) and degree-level education (aOR: 2.659; 95% CI: 1.338, 5.285; P=0.005) and FSD.
Conclusion: This study identifies FSD as a prevalent issue among Malaysian PCPs, emphasising its biopsychosocial complex and the need for a holistic approach. Understanding the cultural determinants of FSD is important to tailor screening and intervention strategies.
{"title":"Prevalence and associated factors of female sexual dysfunction among primary care practitioners in Malaysia: A cross-sectional study.","authors":"Rosli Salwa, Abd Halim Haizlene, Md Yasin Mazapuspavina, Leny Suzana Suddin","doi":"10.51866/oa.883","DOIUrl":"10.51866/oa.883","url":null,"abstract":"<p><strong>Introduction: </strong>Sexual health is integral to quality of life, and female sexual dysfunction (FSD) is a significant public health concern recognised by the World Health Organization. Its prevalence is rising globally, with limited data among primary care practitioners (PCPs). Multifactorial issues such as high work burden in PCPs, coupled with low help-seeking behaviours, contribute to the likelihood of FSD and poor quality of life. This study aimed to determine the prevalence and associated factors of FSD among PCPs in Malaysia.</p><p><strong>Methods: </strong>This cross-sectional study was conducted using a self-administered online questionnaire for 6 months duration in Malaysia. Sociodemographic, marital and clinical data were collected, and two validated questionnaires namely the Malay Version of the Female Sexual Function Index (MVFSFI) and the Depression, Anxiety and Stress Scale (DASS-21) were utilised. Data analysis included descriptive statistics and logistic regression.</p><p><strong>Results: </strong>The study included 382 participants. The prevalence of FSD was 14.7% (95% confidence interval [CI] : 11.1, 18.2) among the participants, and the most affected domain was desire disorder (25.4%). Significant associations were observed between sexual activity two or fewer times per month (adjusted odds ratio [aOR]: 4.880; 95% CI: 2.522, 9.442; P<0.001), depression (aOR: 3.450; 95% CI: 1.653, 7.204; P<0.001) and degree-level education (aOR: 2.659; 95% CI: 1.338, 5.285; P=0.005) and FSD.</p><p><strong>Conclusion: </strong>This study identifies FSD as a prevalent issue among Malaysian PCPs, emphasising its biopsychosocial complex and the need for a holistic approach. Understanding the cultural determinants of FSD is important to tailor screening and intervention strategies.</p>","PeriodicalId":40017,"journal":{"name":"Malaysian Family Physician","volume":"20 ","pages":"55"},"PeriodicalIF":0.0,"publicationDate":"2025-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12334320/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144817848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-07-22eCollection Date: 2025-01-01DOI: 10.51866/cpg.910
Wai Khew Lee, Noreen Zhi Min Ooi, Soo Lee Goh
Introduction: Clinical practice guidelines (CPGs) are important tools that assist primary care doctors in their daily practice. Menopause is a physiological condition that affects all women, and the latest Malaysian CPG on menopause can provide guidance on the optimal management of women facing this condition. However, not all CPGs are of acceptable quality, and it is important that primary care doctors learn to critically appraise CPGs to ensure their practice is evidence-based and relevant to their patients. This review aimed to critically appraise the Clinical Practice Guidelines on the Management of Menopause in Malaysia 2022 to ensure that it is valid and applicable to primary care in Malaysia.
Methods: Three family medicine specialists independently appraised the CPG using the AGREE II Instrument, which consists of six domains assessing the following: (1) scope and purpose, (2) stakeholder involvement, (3) rigour of development, (4) clarity and presentation, (5) applicability and (6) editorial independence. They also provided an overall assessment of quality and recommendation on the use of the CPG following the AGREE II guideline.
Results: The CPG scored >70%, which is the threshold of quality in all domains except for applicability. The reviewers deemed the CPG to be of high quality and recommended its adoption without any modifications.
Discussion: It is important to ensure that recommendations in a CPG are evidence-based and valid before they are adopted into practice. The AGREE II Instrument can assist primary care doctors in critically appraising CPGs.
{"title":"Clinical Practice Guidelines on the Management of Menopause in Malaysia 2022: A review from a primary care perspective.","authors":"Wai Khew Lee, Noreen Zhi Min Ooi, Soo Lee Goh","doi":"10.51866/cpg.910","DOIUrl":"10.51866/cpg.910","url":null,"abstract":"<p><strong>Introduction: </strong>Clinical practice guidelines (CPGs) are important tools that assist primary care doctors in their daily practice. Menopause is a physiological condition that affects all women, and the latest Malaysian CPG on menopause can provide guidance on the optimal management of women facing this condition. However, not all CPGs are of acceptable quality, and it is important that primary care doctors learn to critically appraise CPGs to ensure their practice is evidence-based and relevant to their patients. This review aimed to critically appraise the Clinical Practice Guidelines on the Management of Menopause in Malaysia 2022 to ensure that it is valid and applicable to primary care in Malaysia.</p><p><strong>Methods: </strong>Three family medicine specialists independently appraised the CPG using the AGREE II Instrument, which consists of six domains assessing the following: (1) scope and purpose, (2) stakeholder involvement, (3) rigour of development, (4) clarity and presentation, (5) applicability and (6) editorial independence. They also provided an overall assessment of quality and recommendation on the use of the CPG following the AGREE II guideline.</p><p><strong>Results: </strong>The CPG scored >70%, which is the threshold of quality in all domains except for applicability. The reviewers deemed the CPG to be of high quality and recommended its adoption without any modifications.</p><p><strong>Discussion: </strong>It is important to ensure that recommendations in a CPG are evidence-based and valid before they are adopted into practice. The AGREE II Instrument can assist primary care doctors in critically appraising CPGs.</p>","PeriodicalId":40017,"journal":{"name":"Malaysian Family Physician","volume":"20 ","pages":"50"},"PeriodicalIF":0.0,"publicationDate":"2025-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12334312/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144817844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-07-22eCollection Date: 2025-01-01DOI: 10.51866/tyk.502
Yi Bin Ho, Rebecca Kai Jan Choong, Kit Mun Tan
Hyponatraemia is an exceedingly common condition frequently encountered both in hospital and primary care settings. This medical condition poses unique challenges due to its often subtle and nonspecific symptoms, alongside its diverse array of potential causes. It can result in serious consequences when overlooked or not treated appropriately. Herein, we illustrate the case of a 68-year-old woman who presented with symptomatic hyponatraemia. Although not uncommon, the cause of hyponatraemia in this patient is frequently overlooked but, importantly, is avoidable. This case underlines the necessity of a more watchful approach to prescription of medications, especially in older adults with multiple comorbidities.
{"title":"A cautionary tale of hyponatraemia in an older person: Could This Have Been Prevented?","authors":"Yi Bin Ho, Rebecca Kai Jan Choong, Kit Mun Tan","doi":"10.51866/tyk.502","DOIUrl":"10.51866/tyk.502","url":null,"abstract":"<p><p>Hyponatraemia is an exceedingly common condition frequently encountered both in hospital and primary care settings. This medical condition poses unique challenges due to its often subtle and nonspecific symptoms, alongside its diverse array of potential causes. It can result in serious consequences when overlooked or not treated appropriately. Herein, we illustrate the case of a 68-year-old woman who presented with symptomatic hyponatraemia. Although not uncommon, the cause of hyponatraemia in this patient is frequently overlooked but, importantly, is avoidable. This case underlines the necessity of a more watchful approach to prescription of medications, especially in older adults with multiple comorbidities.</p>","PeriodicalId":40017,"journal":{"name":"Malaysian Family Physician","volume":"20 ","pages":"49"},"PeriodicalIF":0.0,"publicationDate":"2025-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12334321/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144817842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-07-14eCollection Date: 2025-01-01DOI: 10.51866/mol.947
Apichai Wattanapisit
{"title":"Transformation of medical libraries: Reflections from a 20-year journey.","authors":"Apichai Wattanapisit","doi":"10.51866/mol.947","DOIUrl":"10.51866/mol.947","url":null,"abstract":"","PeriodicalId":40017,"journal":{"name":"Malaysian Family Physician","volume":"20 ","pages":"47"},"PeriodicalIF":0.0,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12334322/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144817850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-07-14eCollection Date: 2025-01-01DOI: 10.51866/tyk.453
Nur Hidayah Mohd Fauzi, Nik Ahmad Zuky Nik Lah, Siti Masitah Hamzah, W Fadhlina W Adnan, Adibah Ibrahim, Noorul Balqis Che Ibrahim, Engku Ismail Engku-Husna
Sister Mary Joseph's nodule is a rare but significant clinical sign that often indicates advanced intraabdominal malignancy. It presents as a palpable umbilical nodule and may be the first indication of an occult primary cancer. In this article, we discuss the case of a 58-year-old postmenopausal woman who presented to a primary care clinic with a darkened umbilical lesion and progressive abdominal symptoms. She wps ultimately diagnosed with metastatic endometrial carcinoma. This uncommon presentation highlights the importance of a comprehensive approach to umbilical lesions in the primary care setting. Recognising this subtle sign in primary care can lead to expedited investigations and timely intervention.
{"title":"A dark umbilical nodule in a postmenopausal woman: What is your diagnosis?","authors":"Nur Hidayah Mohd Fauzi, Nik Ahmad Zuky Nik Lah, Siti Masitah Hamzah, W Fadhlina W Adnan, Adibah Ibrahim, Noorul Balqis Che Ibrahim, Engku Ismail Engku-Husna","doi":"10.51866/tyk.453","DOIUrl":"10.51866/tyk.453","url":null,"abstract":"<p><p>Sister Mary Joseph's nodule is a rare but significant clinical sign that often indicates advanced intraabdominal malignancy. It presents as a palpable umbilical nodule and may be the first indication of an occult primary cancer. In this article, we discuss the case of a 58-year-old postmenopausal woman who presented to a primary care clinic with a darkened umbilical lesion and progressive abdominal symptoms. She wps ultimately diagnosed with metastatic endometrial carcinoma. This uncommon presentation highlights the importance of a comprehensive approach to umbilical lesions in the primary care setting. Recognising this subtle sign in primary care can lead to expedited investigations and timely intervention.</p>","PeriodicalId":40017,"journal":{"name":"Malaysian Family Physician","volume":"20 ","pages":"48"},"PeriodicalIF":0.0,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12334313/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144817843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-07-14eCollection Date: 2025-01-01DOI: 10.51866/lte.955
Jazlan Jamaluddin, Siti Nuradliah Jamil, Siti Khamsiah Abd Shukor
{"title":"Garlic burns are not burns.","authors":"Jazlan Jamaluddin, Siti Nuradliah Jamil, Siti Khamsiah Abd Shukor","doi":"10.51866/lte.955","DOIUrl":"10.51866/lte.955","url":null,"abstract":"","PeriodicalId":40017,"journal":{"name":"Malaysian Family Physician","volume":"20 ","pages":"46"},"PeriodicalIF":0.0,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12334324/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144817846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-07-12eCollection Date: 2025-01-01DOI: 10.51866/cr.776
Qingping Joseph Feng, Ian James Long, Su Lone Lim, Ira Siyang Sun, Shiong Wen Low, Chun Peng Goh
Delayed chronic subdural haematoma (cSDH) is a common but potentially serious complication following traumatic brain injury (TBI). Mild TBIs are commonly managed by primary care providers (PCPs), particularly in large, resource-limited settings such as Malaysia, where access to tertiary neurosurgical services may be delayed. Early identification of red-flag signs and symptoms and timely referrals are crucial to prevent clinical deterioration. We describe the case of a 66-year-old man who sustained mild head injury following a vasovagal syncope. His initial brain CT revealed evidence of a small traumatic subarachnoid haemorrhage over the left precentral sulcus, with resolution on an interval scan 24 hours later. He was discharged home without follow-up. Eleven weeks later, he developed bilateral lower-limb weakness and unsteady gait, which prompted an urgent referral by his general practitioner. Repeat CT revealed bilateral acute-on-chronic subdural haematomas, with mass effect requiring emergency burr-hole drainage. The patient showed excellent post-operative improvement and was discharged home on day 4, with no clinical or radiological recurrence on subsequent follow-up. This case highlights the risk of delayed cSDH in patients following mild TBI, even in those discharged with a normal CT scan. PCPs play a pivotal role in recognising high-risk patients, ensuring structured follow-up and facilitating timely specialist referral. We advocate for updating the Malaysian head injury guidelines to incorporate routine follow-up protocols for at-risk patients, modelled after international standards.
{"title":"Development of chronic subdural haematoma from mild head injury: A case report and review of current Malaysian guidelines on traumatic brain injury.","authors":"Qingping Joseph Feng, Ian James Long, Su Lone Lim, Ira Siyang Sun, Shiong Wen Low, Chun Peng Goh","doi":"10.51866/cr.776","DOIUrl":"10.51866/cr.776","url":null,"abstract":"<p><p>Delayed chronic subdural haematoma (cSDH) is a common but potentially serious complication following traumatic brain injury (TBI). Mild TBIs are commonly managed by primary care providers (PCPs), particularly in large, resource-limited settings such as Malaysia, where access to tertiary neurosurgical services may be delayed. Early identification of red-flag signs and symptoms and timely referrals are crucial to prevent clinical deterioration. We describe the case of a 66-year-old man who sustained mild head injury following a vasovagal syncope. His initial brain CT revealed evidence of a small traumatic subarachnoid haemorrhage over the left precentral sulcus, with resolution on an interval scan 24 hours later. He was discharged home without follow-up. Eleven weeks later, he developed bilateral lower-limb weakness and unsteady gait, which prompted an urgent referral by his general practitioner. Repeat CT revealed bilateral acute-on-chronic subdural haematomas, with mass effect requiring emergency burr-hole drainage. The patient showed excellent post-operative improvement and was discharged home on day 4, with no clinical or radiological recurrence on subsequent follow-up. This case highlights the risk of delayed cSDH in patients following mild TBI, even in those discharged with a normal CT scan. PCPs play a pivotal role in recognising high-risk patients, ensuring structured follow-up and facilitating timely specialist referral. We advocate for updating the Malaysian head injury guidelines to incorporate routine follow-up protocols for at-risk patients, modelled after international standards.</p>","PeriodicalId":40017,"journal":{"name":"Malaysian Family Physician","volume":"20 ","pages":"45"},"PeriodicalIF":0.0,"publicationDate":"2025-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12334315/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144817845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-07-09eCollection Date: 2025-01-01DOI: 10.51866/cr.668
Asma Amirah Mohd Noor, Azwanis Abdul Hadi, Abdul Rahman Che Abdul Rahim
Palmoplantar keratoderma (PPK) is a dermatological disorder characterised by excessive thickening of the palms and soles, encompassing more than 20 conditions. The disease is often misdiagnosed in primary care settings, leading to unnecessary treatments and delays. We present the case of a 3-year-old girl with skin thickening on both her palms and soles persisting for 2 years, initially believed to be an acquired condition. Subsequent evaluation revealed a family history of similar skin lesions. This case report highlights the crucial role of family physicians in differentiating hereditary from acquired PPK, especially in settings where advanced testing is unavailable. Implementing a structured diagnostic approach at the primary care level can significantly improve patient management and reduce morbidities and healthcare costs. This case contributes to the existing knowledge in this field, where hereditary PPK remains underexplored.
{"title":"A case report of palmoplantar keratoderma in a 3-year-old girl: A structured approach in primary care settings.","authors":"Asma Amirah Mohd Noor, Azwanis Abdul Hadi, Abdul Rahman Che Abdul Rahim","doi":"10.51866/cr.668","DOIUrl":"10.51866/cr.668","url":null,"abstract":"<p><p>Palmoplantar keratoderma (PPK) is a dermatological disorder characterised by excessive thickening of the palms and soles, encompassing more than 20 conditions. The disease is often misdiagnosed in primary care settings, leading to unnecessary treatments and delays. We present the case of a 3-year-old girl with skin thickening on both her palms and soles persisting for 2 years, initially believed to be an acquired condition. Subsequent evaluation revealed a family history of similar skin lesions. This case report highlights the crucial role of family physicians in differentiating hereditary from acquired PPK, especially in settings where advanced testing is unavailable. Implementing a structured diagnostic approach at the primary care level can significantly improve patient management and reduce morbidities and healthcare costs. This case contributes to the existing knowledge in this field, where hereditary PPK remains underexplored.</p>","PeriodicalId":40017,"journal":{"name":"Malaysian Family Physician","volume":"20 ","pages":"42"},"PeriodicalIF":0.0,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12334319/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144817841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-07-06eCollection Date: 2025-01-01DOI: 10.51866/cr.858
Mohd Hafis Zul Arif Awang, Khasnur Abd Malek, Norliana Dalila Mohamad Ali, Effat Omar
We report the case of a 54-year-old woman with poorly controlled type 2 diabetes mellitus, dyslipidaemia, hypertension and a 3-month history of fixed cutaneous sporotrichosis treated with itraconazole 200 mg once daily. She subsequently presented with progressive enlarging nodular lesions on her left forearm, wrist and right forehead, with right ankle pain. Imaging revealed multifocal osseous involvement, including small lucent lesions in the right frontal bone and left distal radius and aggressive lesions in the right ankle and left radius. MRI of the right ankle showed an enhancing lesion in the distal fibula with cortical destruction. A biopsy showed chronic suppurative granulomatous inflammation, and a fungal culture grew Sporothrix spp. The patient underwent surgical debridement of the ankle and was continued on itraconazole for 1 year. She had complete resolution of all her lesions, resulting in no residual functional disabilities observed during follow-up.
{"title":"Systemic disseminated zoonotic sporotrichosis with multifocal bone involvement: A case report.","authors":"Mohd Hafis Zul Arif Awang, Khasnur Abd Malek, Norliana Dalila Mohamad Ali, Effat Omar","doi":"10.51866/cr.858","DOIUrl":"10.51866/cr.858","url":null,"abstract":"<p><p>We report the case of a 54-year-old woman with poorly controlled type 2 diabetes mellitus, dyslipidaemia, hypertension and a 3-month history of fixed cutaneous sporotrichosis treated with itraconazole 200 mg once daily. She subsequently presented with progressive enlarging nodular lesions on her left forearm, wrist and right forehead, with right ankle pain. Imaging revealed multifocal osseous involvement, including small lucent lesions in the right frontal bone and left distal radius and aggressive lesions in the right ankle and left radius. MRI of the right ankle showed an enhancing lesion in the distal fibula with cortical destruction. A biopsy showed chronic suppurative granulomatous inflammation, and a fungal culture grew Sporothrix spp. The patient underwent surgical debridement of the ankle and was continued on itraconazole for 1 year. She had complete resolution of all her lesions, resulting in no residual functional disabilities observed during follow-up.</p>","PeriodicalId":40017,"journal":{"name":"Malaysian Family Physician","volume":"20 ","pages":"40"},"PeriodicalIF":0.0,"publicationDate":"2025-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12334314/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144817849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}