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Validation of Arabic version of Revised Memory and Behavior Problems Checklist ( RMBPC ). 阿拉伯语版《记忆与行为问题检查表》(RMBPC)的验证。
Pub Date : 2022-10-01 DOI: 10.21608/ejgg.2022.267990
*. Enas Hafez et al.,
: Background: With the increase in population aging ; there is increase in the prevalence of dementia and this will be associated with development of behavioral and psychological symptoms which are very common and distressing to the caregivers. The most problematic symptoms associated with caregiver stress are agitation, aggression, wandering, purposeless activity, disinhibition, bing eating..etc,. Revised Memory and Behavioral Checklist RMBPC is a 24 items questionnaire used to measure the frequency of behavioral and psychological symptoms of dementia (BPSD) and the degree of upset of caregivers (reaction) to these symptoms. Aim: to test validity and reliability of Arabic version of Revised Memory and behavioral problem checklist (RMBPC). Subjects and Methods: A cross sectional study involving 100 caregivers of elderly patients previously diagnosed with dementia (moderate to severe) in community dwellings and all of them applied to fill out the Arabic version of RMBPC questionnaire. The questionnaire was subjected to Arabic translation and the reliability and validity were done to the test. Results: Arabic version of RMBPC is reliable by test re-test reliability. Alpha cronbach and internal consistency by item total correlation showing that there were seven questions of weak correlation. So they are deleted except question 1 and question 13 because of their clinical significance. After deletion of weak questions, the test is valid by construct validity. Construct validity was evaluated by using pearson's correlation coefficient showing that all subscales are strongly correlated with total score. Construct validity by using correlation matrix of RMBPC and other tools ; Zarit , Cornell , ADL &IADL showing that RMBPC is strongly correlated to Zarit and Cornell . Conclusion: The Arabic version of 19-items RMBPC is valid and reliable.
背景:随着人口老龄化的加剧;痴呆症的患病率在增加,这将与行为和心理症状的发展有关,这些症状非常普遍,对照顾者来说也很痛苦。与照顾者压力相关的最有问题的症状是躁动、攻击性、徘徊、无目的的活动、失控、暴饮暴食等。修订记忆与行为检查表(RMBPC)是一份24项的问卷,用于测量痴呆症(BPSD)的行为和心理症状的频率以及照顾者对这些症状的不安程度(反应)。目的:检验阿拉伯文版《记忆与行为问题订正表》的效度和信度。对象与方法:采用横断面研究方法,选取100名社区住宅老年痴呆患者(中重度)的护理人员,填写阿拉伯文版RMBPC问卷。问卷进行阿拉伯文翻译,并进行信度和效度检验。结果:经重测信度,阿拉伯文版本的RMBPC是可靠的。经项目总相关的Alpha cronbach和内部一致性显示有7个问题的弱相关。所以除了问题1和问题13,它们都被删除了因为它们的临床意义。在删除弱题后,测试通过构念效度达到有效。构念效度采用pearson相关系数评估,显示各子量表与总分呈强相关。运用相关矩阵等工具构建效度;Zarit, Cornell, ADL &IADL表明RMBPC与Zarit和Cornell有较强的相关性。结论:阿拉伯语版19项RMBPC有效、可靠。
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引用次数: 0
Screening of Nutritional Deficiency Manifestations Among Egyptian Elderly: Cross-sectional study 筛选营养缺乏表现在埃及老年人:横断面研究
Pub Date : 2022-10-01 DOI: 10.21608/ejgg.2022.267996
*. Emad El-Shebiney et al.,
Background : Nutritional deficiencies are frequently not detected or misdiagnosed in old age as they could mimic the natural changes associated with aging Aim : To screen the clinical manifestations of nutritional deficiencies among the elderly . Method: A cross-sectional study was conducted on 100 elderly participants with chronic diseases, aged 65 or more, chosen randomly from the outpatient clinic and inpatient at Menoufia university hospital, Egypt. Tools of the study: Demographic and clinical data; a checklist of symptoms and signs of common nutritional deficiency; and a subjective global assessment (SGA). Results : the distribution of potential nutritional clinical manifestations among elderly revealed was variable ; skin rash (29%), easy bruising (41%), loss or thinning of hair (75%), spooning of nails (20%), impaired vision at night (37%), clouding and corneal dryness. (57%), bleeding gums (56%), bone deformities (bowlegs, knocked knees, curved spine) (6%), bone tenderness (49%). There were statistically significant difference between SGA and the following chronic diseases: (DM, hepatic, renal, and rheumatic) also significance associations between (skin rash in sun-exposed areas in hepatic diseases (p = 0.04), spooning of nails in renal disease (p = 0.06), Impaired night vision in cardiac and diabetic patients (p = 0.001), rheumatic diseases had more bone tenderness and diarrhea (p = 0.001) Conclusion : The most common nutritional deficiency manifestations among elderly were; thinning or loss of hair, corneal drying or clouding, bleeding gum, easy bruising, and bone tenderness. SGA based nutritional status of elderly was (35%) well-nourished, (49%) mild to moderate, and (16%) severe malnutrition.
背景:营养缺乏症在老年人中往往未被发现或误诊,因为营养缺乏症可以模仿与衰老相关的自然变化。目的:筛选老年人营养缺乏症的临床表现。方法:采用横断面研究方法,从埃及Menoufia大学医院门诊和住院患者中随机抽取100例65岁及以上的老年慢性病患者。研究工具:人口统计学和临床数据;常见营养缺乏的症状和体征清单;以及主观全球评估(SGA)。结果:老年人潜在营养临床表现的分布是可变的;皮疹(29%)、易瘀伤(41%)、头发脱落或稀疏(75%)、指甲脱落(20%)、夜间视力受损(37%)、混浊和角膜干燥。(57%),牙龈出血(56%),骨骼畸形(弓形腿、撞膝、脊柱弯曲)(6%),骨压痛(49%)。SGA与慢性疾病(DM、肝、肾、风湿病)、日晒区皮疹(p = 0.04)、匙式指甲(p = 0.06)、夜视障碍(p = 0.001)、风湿病多发骨痛和腹泻(p = 0.001)之间的相关性均有统计学意义。老年人最常见的营养缺乏表现为;头发稀疏或脱落,角膜干燥或混浊,牙龈出血,容易瘀伤,骨痛。基于SGA的老年人营养状况为营养良好(35%)、轻度至中度(49%)和严重营养不良(16%)。
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引用次数: 0
Blood Urea Nitrogen to Albumin Ratio is a Predictor of Mortality among Hospitalized Geriatric Patients with COVID-19. 血液尿素氮与白蛋白比是住院老年COVID-19患者死亡率的预测因子
Pub Date : 2022-10-01 DOI: 10.21608/ejgg.2022.267997
*. Khalid E. Elsorady et al.,
: Aim : This study aims to determine predictors of mortality among hospitalized geriatric patients with COVID-19 with a particular concern about the predictive value of blood urea nitrogen to albumin ratio (BAR). Methods : A retrospective cohort study included 114 geriatric patients (aged ≥ 60 years) admitted to a geriatrics hospital for isolation. A review of the medical files of participants was conducted to extract data regarding age, sex, comorbidities, clinical manifestations of COVID-19 and laboratory data including haematology, biochemistry and inflammatory markers on admission. BAR and Charlson comorbidity index (CCI) were calculated. The primary outcome was in-hospital mortality. Appropriate statistical analyses were operated. RESULTS : 59 (51.8%) patients died at the hospital. Comorbidities associated with mortality included diabetes mellitus, old stroke, hypertension, and cardiac disease besides higher CCI. Reporting of fever, fatigue, sore throat and delirium /altered mental status were also associated with mortality. Significant biomarkers included lower hemoglobin and serum albumin, higher total leukocyte count, serum creatinine, blood urea nitrogen, lactate dehydrogenase, D-dimer, c-reactive protein (CRP) and BAR. BAR at a cutoff of 12.92 mg/gm had the best predictive performance for mortality. Serum BAR > 12.92 mg/gm, albumin < 3.05 g/dl and CRP > 108 mg/l were independent predictors of in-hospital mortality CONCLUSION : Serum BAR > 12.92 mg/gm, albumin < 3.05 g/dl and CRP > 108 mg/l are independent predictors of mortality among hospitalized geriatric patients with COVID-19. BAR is a convenient biomarker and has the best predictive performance to early pick up COVID-19 geriatric patients at high risk of mortality.
目的:本研究旨在确定COVID-19住院老年患者死亡率的预测因素,特别关注血液尿素氮与白蛋白比(BAR)的预测价值。方法:回顾性队列研究纳入114例在老年医院接受隔离的老年患者(年龄≥60岁)。回顾参与者的医疗档案,提取年龄、性别、合并症、COVID-19临床表现以及入院时血液学、生物化学和炎症标志物等实验室数据。计算BAR和Charlson共病指数(CCI)。主要终点是住院死亡率。进行了适当的统计分析。结果:59例(51.8%)患者在医院死亡。与死亡率相关的合并症包括糖尿病、老年卒中、高血压和心脏病,以及较高的CCI。报告发烧、疲劳、喉咙痛和谵妄/精神状态改变也与死亡率有关。显著的生物标志物包括血红蛋白和血清白蛋白降低,白细胞总数、血清肌酐、血尿素氮、乳酸脱氢酶、d -二聚体、c反应蛋白(CRP)和BAR升高。以12.92 mg/gm为临界值的BAR对死亡率的预测效果最好。结论:血清BAR - > 12.92 mg/gm、白蛋白< 3.05 g/dl、CRP - > 108 mg/l是住院老年COVID-19患者死亡率的独立预测因子。BAR是一种便捷的生物标志物,对早期发现的高死亡风险老年患者具有最佳的预测效果。
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引用次数: 0
Study of the level of male sex hormones in elderly patients suffering from depression 老年抑郁症患者男性性激素水平的研究
Pub Date : 2022-03-01 DOI: 10.21608/ejgg.2022.237002
Nany Hasan El Gayar, Mohamed Samy Gad, Akram El Deghedy, A. Mohsen
Introduction : Testosterone is hormone that has unique effect on man ’ s total body. Manifestations of low testosterone level in adult may include: low sex drive, emotional, psychological and behavioral changes. There is strong relation between depression and sexual dysfunction. Objective: the aim was to evaluate the level of male sex hormones in elderly men suffering from depression. Methods: This study included 60 subjects aged ≥ 65 years who were classified into two groups. Group I included 30 elderly depressed males, group II included 30 elderly non-depressed males. All participants were subjected to detailed history taking, routine laboratory investigations, sex hormonal assessment [total testosterone, sex hormone-binding globulin (SHBG), free androgen index(FAI)=total testosterone/SHBG*100] and depression scoring using Beck Depression Inventory(BDI). Results: There was no significant differences regarding total testosterone levels however, the level of SHBG was significantly lower in group I and free androgen index (FAI)was significantly higher in group I, there were no significant differences regarding the marital status or smoking. There were no significant correlations between the studied groups regarding age with total testosterone, SHBG or free androgen index. There were non-significant negative correlations between BDI and total testosterone or SHBG and non-significant positive correlation between BDI and FAI in group l, but in group ll there were non-significant positive correlations between BDI and total testosterone or FAI and non-significant negative correlations between BDI and SHBG in group ll. Conclusion: The level of total testosterone revealed no significant change but SHBG was lower and FAI was higher in depressed elderly males.
简介:睾酮是一种对人体有独特作用的激素。成人睾酮水平低的表现包括:性欲低下、情绪、心理和行为改变。抑郁症和性功能障碍之间有很强的联系。目的:评价老年男性抑郁症患者的男性性激素水平。方法:60例年龄≥65岁的患者分为两组。第一组30名老年抑郁症男性,第二组30名老年非抑郁症男性。所有参与者均接受详细的病史记录、常规实验室检查、性激素评估[总睾酮、性激素结合球蛋白(SHBG)、游离雄激素指数(FAI)=总睾酮/SHBG*100],并使用贝克抑郁量表(BDI)进行抑郁评分。结果:两组总睾酮水平差异无统计学意义,但ⅰ组SHBG水平显著低于ⅰ组,游离雄激素指数(FAI)显著高于ⅰ组,婚姻状况、吸烟情况差异无统计学意义。年龄与总睾酮、SHBG或游离雄激素指数之间无显著相关性。1组患者BDI与总睾酮、SHBG呈非显著负相关,BDI与FAI呈非显著正相关,而2组患者BDI与总睾酮、FAI呈非显著正相关,2组患者BDI与SHBG呈非显著负相关。结论:老年男性抑郁症患者总睾酮水平无明显变化,但SHBG较低,FAI较高。
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引用次数: 0
Comparison between two common tools for cognitive screening in a sample of illiterate Egyptian seniors 在不识字的埃及老年人样本中两种常见认知筛查工具的比较
Pub Date : 2022-03-01 DOI: 10.21608/ejgg.2022.236998
M. Tarek, Halla Sweed, H. Wahba
Background: Mild cognitive impairment (MCI) and mild dementia are common problems in the elderly that may pass unnoticed till deteriorated or affect elderly's function especially activities of daily living (ADL). MCI is also associated with significant morbidity and mortality. Patients with MCI may develop any type of dementia as Alzheimer's disease (AD), vascular dementia and other types of dementias by rates about 8.1%, 1.9% and 9.6% respectively per year, so early detection and management will benefit both patient and caregiver. Non amnestic MCI is less common to progress to dementia than amnestic type while about 16% of cases may regress to normal. Due to the absence of actual disease-modifying treatment for late dementia, diagnosis and disease involvement at an early stage especially at the MCI stage has been widely accepted as a critical policy in disease management that could consequently affect long-term results and prevent its progression. MCI can be diagnosed using mental status evaluation in addition to other neurological, psychiatric, medical examination, neuroimaging and biological biomarkers. There are a lot of tools that can be used for screening of cognitive impairment of variable degrees of sensitivity and specificity such as Minimental State Examination (MMSE) and Montreal Cognitive Assessment Basic (MoCA-B). The aim of the work is to compare between MMSE and MoCA-B, which are commonly used cognitive screening tools, in illiterate Egyptian seniors. Methods: An observational clinical study was conducted on 100 illiterate Egyptian elderly having variable comorbidities aged ≥ 60 years recruited from the outpatient clinics of Mansoura university hospitals. Full history taking, comprehensive geriatric assessment, Minimental State Examination (MMSE) and Montreal Cognitive Assessment Basic (MoCA-B) were performed for all participants. Results: The current study showed that patients diagnosed as normal by MMSE were graded MCI and mild dementia by MoCA-B and so there was no significant agreement between MoCA-B and MMSE scale grades among the studied cases in illiterate Egyptian seniors ≥ 60 years (p=0.062). Conclusions: No agreement between MoCA-B and MMSE scale grades among the studied cases.
背景:轻度认知障碍(MCI)和轻度痴呆是老年人常见的问题,往往不被注意,直至恶化或影响老年人的功能,特别是日常生活活动(ADL)。轻度认知损伤还与显著的发病率和死亡率相关。MCI患者可能发展为任何类型的痴呆,如阿尔茨海默病(AD)、血管性痴呆和其他类型的痴呆,发病率分别为每年8.1%、1.9%和9.6%,因此早期发现和管理将使患者和护理人员受益。与遗忘型相比,非遗忘型轻度认知损伤发展为痴呆的几率较低,而约16%的病例可恢复正常。由于缺乏对晚期痴呆的实际疾病改善治疗,早期诊断和疾病介入,特别是在MCI阶段,已被广泛接受为疾病管理的关键政策,因此可能影响长期结果并防止其进展。除了其他神经学、精神病学、医学检查、神经影像学和生物生物标志物外,还可以使用精神状态评估来诊断轻度认知障碍。有很多工具可用于筛查不同程度的敏感性和特异性的认知障碍,如最小状态检查(MMSE)和蒙特利尔认知评估基础(MoCA-B)。这项工作的目的是比较MMSE和MoCA-B,这是一种常用的认知筛查工具,在文盲的埃及老年人中。方法:对从曼苏拉大学附属医院门诊招募的100名年龄≥60岁、有不同合并症的埃及文盲老年人进行观察性临床研究。对所有参与者进行了完整的病史记录、综合老年评估、最小状态检查(MMSE)和蒙特利尔认知评估基础(MoCA-B)。结果:目前的研究显示,经MMSE诊断为正常的患者经MoCA-B分级为轻度轻度痴呆,因此在研究的60岁以上的埃及文盲老年人中,MoCA-B和MMSE分级之间没有显著的一致性(p=0.062)。结论:在研究的病例中,MoCA-B和MMSE评分之间没有一致性。
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引用次数: 0
Primary Care Physicians’ Knowledge and Attitude towards Palliative Care. Is it time for integration? 初级保健医师对姑息治疗的知识与态度。现在是整合的时候了吗?
Pub Date : 2022-03-01 DOI: 10.21608/ejgg.2022.237001
Wafaa Abdel Gawad, A. Al-Ansari, S. Suroor, Sobhi Aboserea
: Purpose: Despite the unquestionable role of the primary care physicians in carrying the majority of high-quality care for patients under palliative care is well-known especially with the senior population, it is still not clear what their existing level of knowledge and attitude to palliative care is. Unfortunately, there is limited research. So, we aimed at detecting the knowledge and attitude of the primary care physicians toward palliative care in Kuwait. Patients and Methods: A survey using the Palliative Care Attitude and Knowledge questionnaire (PCAK) applied to twenty-five primary care clinics in Kuwait were selected by stratified random sampling method and 284 physicians were included. Results: The response rate was 79.2%(n=225). The uncertain attitude towards palliative care was reported in 53.3% (n=120) of primary care physicians while only 15(6.7%) had good knowledge. Only 31.2% reported excellent or very good experience in the management of pain and other symptoms respectively. Moreover, unfamiliarity with palliative care services in their community or length and types of coverage under palliative care benefits was reported in 141(62.7%) and 119 (52.9%). Regarding opioid initiation, types, toxicity and its role in refractory dyspnea, and the proper management of catastrophic bleeding, less than 50% responded appropriately. A higher knowledge score was a positive prognosticator for more optimistic attitude scores (OR: 1.088, 95% CI: 1.012-1.170, P-value: 0.023) Conclusion: The uncertain attitude and poor knowledge were reported in the majority of primary care physicians towards palliative care. Integrating palliative care into primary health care systems has to be initiated as possible to lessen the suffering of those patients and to meet the challenges of the ageing society.
目的:尽管初级保健医生在为姑息治疗患者提供大多数高质量护理方面的作用毋庸置疑,尤其是在老年人群中,但他们对姑息治疗的现有知识水平和态度尚不清楚。不幸的是,研究有限。因此,我们旨在检测科威特初级保健医生对姑息治疗的知识和态度。患者与方法:采用分层随机抽样的方法,采用姑息治疗态度与知识问卷(PCAK)对科威特25家初级保健诊所的284名医生进行调查。结果:有效率为79.2%(n=225)。53.3% (n=120)的初级保健医生对姑息治疗的态度不确定,仅有15名(6.7%)的医生对姑息治疗有良好的了解。只有31.2%的人在处理疼痛和其他症状方面分别表现出优秀或非常好的经验。此外,141人(62.7%)和119人(52.9%)报告不熟悉社区的姑息治疗服务或姑息治疗福利覆盖的长度和类型。关于阿片类药物的起始、类型、毒性及其在难治性呼吸困难中的作用,以及对灾难性出血的适当处理,不到50%的患者反应适当。知识得分越高,乐观态度得分越高(OR: 1.088, 95% CI: 1.012-1.170, p值:0.023)结论:大多数初级保健医生对姑息治疗存在态度不确定和知识贫乏的问题。必须尽可能将姑息治疗纳入初级卫生保健系统,以减轻这些患者的痛苦,并应对老龄化社会的挑战。
{"title":"Primary Care Physicians’ Knowledge and Attitude towards Palliative Care. Is it time for integration?","authors":"Wafaa Abdel Gawad, A. Al-Ansari, S. Suroor, Sobhi Aboserea","doi":"10.21608/ejgg.2022.237001","DOIUrl":"https://doi.org/10.21608/ejgg.2022.237001","url":null,"abstract":": Purpose: Despite the unquestionable role of the primary care physicians in carrying the majority of high-quality care for patients under palliative care is well-known especially with the senior population, it is still not clear what their existing level of knowledge and attitude to palliative care is. Unfortunately, there is limited research. So, we aimed at detecting the knowledge and attitude of the primary care physicians toward palliative care in Kuwait. Patients and Methods: A survey using the Palliative Care Attitude and Knowledge questionnaire (PCAK) applied to twenty-five primary care clinics in Kuwait were selected by stratified random sampling method and 284 physicians were included. Results: The response rate was 79.2%(n=225). The uncertain attitude towards palliative care was reported in 53.3% (n=120) of primary care physicians while only 15(6.7%) had good knowledge. Only 31.2% reported excellent or very good experience in the management of pain and other symptoms respectively. Moreover, unfamiliarity with palliative care services in their community or length and types of coverage under palliative care benefits was reported in 141(62.7%) and 119 (52.9%). Regarding opioid initiation, types, toxicity and its role in refractory dyspnea, and the proper management of catastrophic bleeding, less than 50% responded appropriately. A higher knowledge score was a positive prognosticator for more optimistic attitude scores (OR: 1.088, 95% CI: 1.012-1.170, P-value: 0.023) Conclusion: The uncertain attitude and poor knowledge were reported in the majority of primary care physicians towards palliative care. Integrating palliative care into primary health care systems has to be initiated as possible to lessen the suffering of those patients and to meet the challenges of the ageing society.","PeriodicalId":405276,"journal":{"name":"The Egyptian Journal of Geriatrics and Gerontology","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123806885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Caring for Geriatric Dementia Patients in Egypt: The Effect of an Educational Training Program for Caregivers 照顾老年痴呆患者在埃及:教育培训计划的护理人员的影响
Pub Date : 2022-03-01 DOI: 10.21608/ejgg.2022.237000
Ehsan Abdelzaher, Rania M. Elakkad, S. Rohaiem, Asmaa F. Abdellah, S. Hamza
Background : Most persons with dementia in Egypt live at home, supported mainly by family caregivers, who often develop psychological problems due to this burden affecting their quality of life. The aim of the study is to assess the effect of a caregiver training program on relieving psychological problems of Egyptian caregivers of elderly patients with dementia. A prospective interventional study was conducted on one hundred caregivers of elderly demented patients recruited from the outpatient clinic at Abbasia Psychiatric Health Hospital. The sample was divided into two groups, a control group and a treatment group subjected to a 5 steps training program. Results : The training program was associated with a significant reduction in caregiver burden (P<0.001). Severity of depression decreased from 30% to 20% in the treatment group after education. Similarly, anxiety, assessed by the Spielberger State-Trait Anxiety Inventory (STAI) was observed to decrease from 80% to 70%. Conclusion : Training of family caregivers of persons with dementia can reduce family caregivers’ burden, stress, and improve their quality of life. Therefore, it is highly recommended.
背景:在埃及,大多数痴呆症患者生活在家中,主要由家庭照顾者提供支持,由于这种负担影响了他们的生活质量,他们经常出现心理问题。该研究的目的是评估护理人员培训计划对缓解老年痴呆症患者的埃及护理人员的心理问题的影响。一项前瞻性介入研究从Abbasia精神病院门诊招募了100名老年痴呆患者的护理人员。样本分为两组,对照组和治疗组接受5步训练计划。结果:培训计划与照顾者负担的显著减轻相关(P<0.001)。在接受教育后,治疗组抑郁症的严重程度从30%下降到20%。同样,通过Spielberger状态-特质焦虑量表(STAI)评估的焦虑也从80%下降到70%。结论:对痴呆患者的家庭照顾者进行培训,可以减轻家庭照顾者的负担和压力,提高其生活质量。因此,强烈推荐使用。
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引用次数: 0
The predictive role of red cell distribution width, neutrophil-lymphocyte ratio and platelet lymphocyte ratio on mortality in COVID-19 patients admitted to intensive care units 红细胞分布宽度、中性粒细胞-淋巴细胞比值和血小板淋巴细胞比值对重症监护病房新冠肺炎患者死亡率的预测作用
Pub Date : 2022-03-01 DOI: 10.21608/ejgg.2022.237005
H. Tawfik, Radwa AbdelKader
Background: Coronavirus -19 (COVID-19) infection is associated with increased mortality and long-term complications. Aim: Comparison between neutrophil lymphocyte ratio (NLR), platelet lymphocyte ratio (PLR) and red cell distribution width (RDW) in their role in mortality detection. Methods: A retrospective cohort study collecting data from medical records of 114 patients admitted to quarantine hospital intensive care unit in Ain-Shams University due to COVID-19 infection. Data was collected regarding demography, comorbidities, length of hospital stay. Blood samples were withdrawn including complete blood count and c-reactive protein. RDW was recorded, NLR and PLR were calculated. Patients were divided according to their outcome into cases including 57 patients who died and controls including 57 survivor patients with comparison between both groups. Regression analysis was performed to detect predictors of mortality. Results: The mean age of the study population was 73.61 and more than half of them were males. Diabetes mellitus and bronchial asthma were more prevalent in cases. By univariate regression analysis diabetes mellitus and NLR were associated with increased mortality. By multivariate analysis NLR is the only factor predicting mortality. NLR >12.4 had 57.89% sensitivity and 78.95% specificity for predicting mortality. Conclusion: NLR is the best inflammatory marker included the study and is associated with increased mortality in severe and critical COVID-19 patients. Diabetes mellitus is associated with increased mortality in those patients.
背景:冠状病毒-19 (COVID-19)感染与死亡率增加和长期并发症相关。目的:比较中性粒细胞淋巴细胞比(NLR)、血小板淋巴细胞比(PLR)和红细胞分布宽度(RDW)在死亡率检测中的作用。方法:采用回顾性队列研究方法,收集艾因-沙姆斯大学隔离医院重症监护病房收治的114例COVID-19感染患者的病历资料。收集有关人口统计学、合并症、住院时间的数据。抽取血液样本,包括全血细胞计数和c反应蛋白。记录RDW,计算NLR和PLR。根据预后将患者分为两组,分别为57例死亡患者和57例存活患者。进行回归分析以检测死亡率的预测因子。结果:研究人群平均年龄为73.61岁,男性占一半以上。糖尿病、支气管哮喘多见。通过单因素回归分析,糖尿病和NLR与死亡率增加相关。通过多变量分析,NLR是预测死亡率的唯一因素。NLR >12.4预测死亡率的敏感性为57.89%,特异性为78.95%。结论:NLR是本研究中最好的炎症标志物,与COVID-19重症危重症患者死亡率升高相关。糖尿病与这些患者的死亡率增加有关。
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引用次数: 0
Diagnostic Performance of Ain-Shams Cognitive Assessment tool among older adults with Mild Cognitive Impairment Ain-Shams认知评估工具在老年轻度认知障碍患者中的诊断效果
Pub Date : 2022-03-01 DOI: 10.21608/ejgg.2022.237003
Safinaz Abousamra, Khaled El Sorady, Hossam Arafa Ghazi, H. Mohamed, S. E. El Said, Somia Ebeid
Background: A new neuropsychiatric battery named Ain-shams cognitive assessment tool (ASCA) targets MCI and dementia diagnosis. The current study aims to determine the diagnostic performance of ASCA among older adults with MCI. Methods: A comparative cross-sectional study included one hundred elderly persons (aged ≥60 years) both males and females recruited from El-Mansoura university hospital outpatients’ clinics, divided into 2 groups based on the Arabic version of Rowland Universal Dementia Assessment Scale (A-RUDAS) score: Group A: Fifty participants with MCI, defined as A-RUDAS score<24. Group B: Fifty participants with normal cognitive function. The data collection process included: Step 1: Comprehensive geriatric assessment. Step 2: cognitive assessment by using A-RUDAS, Step 3: Applying ASCA. Step 4: Statistical analysis was done. RESULTS: The Mean age in the MCI group was 68.9±4.1 years. Participants who were assisted in IADL and had a higher risk of malnutrition were significantly more frequent in the MCI group, P-value 0.004 and 0.02 respectively. The total ASCA score for the current study participants at cut-off point ≤95 had perfect diagnostic characteristics in differentiating MCI from normal participants with sensitivity and specificity of 100%. The total score of Verbal learning and recall tests of ASCA of the current study participants at ≤39 had the highest MCI diagnostic performance with sensitivity and specificity 96.0% and 90.0% respectively. There was no statistically significant association between the participants` educational level and their performance in ASCA battery tests. CONCLUSION: ASCA was a valid tool for MCI diagnosis among literate and illiterate participants.
背景:一种新的神经精神病学电池- Ain-shams认知评估工具(ASCA)用于MCI和痴呆的诊断。目前的研究旨在确定老年轻度认知障碍患者ASCA的诊断表现。方法:采用比较横断面研究,从El-Mansoura大学医院门诊部招募100名年龄≥60岁的男女老年人,根据阿拉伯语版Rowland通用痴呆评估量表(A- rudas)评分分为2组:A组:50名MCI患者,定义为A- rudas评分<24。B组:50名认知功能正常的受试者。数据收集过程包括:步骤1:全面的老年评估。第二步:使用A-RUDAS进行认知评估;第三步:应用ASCA。第四步:统计分析。结果:MCI组患者平均年龄为68.9±4.1岁。在MCI组中,辅助进行IADL且营养不良风险较高的参与者出现的频率明显更高,p值分别为0.004和0.02。在截断点≤95时,本研究参与者的ASCA总分在区分MCI与正常参与者方面具有完美的诊断特征,敏感性和特异性均为100%。本研究受试者在ASCA的言语学习和回忆测试总分≤39分时诊断MCI的灵敏度和特异性最高,分别为96.0%和90.0%。参与者的教育水平与他们在ASCA电池测试中的表现之间没有统计学上的显著关联。结论:ASCA是识字和不识字的MCI诊断的有效工具。
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引用次数: 0
The prevalence of sleep disorders among elderly females complaining of subjective cognitive decline 主诉主观认知能力下降的老年女性睡眠障碍的患病率
Pub Date : 2021-10-01 DOI: 10.21608/ejgg.2021.275620
Eman Gamal Afifi, H. Wahba, Ekramy Eissa Abdelrahman, M. Khater
,
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引用次数: 0
期刊
The Egyptian Journal of Geriatrics and Gerontology
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