Clinica e Investigacion en Ginecologia y Obstetricia最新文献_第2页

Adenocarcinoma de células claras primario del cuello uterino sin exposición intrauterina al dietilestilbestrol en una adolescente de 15 años. Un caso clinicopatológico 15岁少女未在宫内接触乙酯酯的原发性宫颈白细胞腺癌。临床病理病例

IF 0.1 Q4 OBSTETRICS & GYNECOLOGY

Clinica e Investigacion en Ginecologia y Obstetricia

Pub Date : 2025-10-01 Epub Date: 2025-10-27 DOI: 10.1016/j.gine.2025.101070

R. Sarabia Ochoa , J.P. García de la Torre , A. Canosa Fernández

Introduction

Clear cell adenocarcinoma of the cervix is a rare histological variant that is usually associated with intrauterine exposure to diethylstilbestrol (DES).

Main symptoms and/or clinical findings

A 15-year-old girl, virgin, with vaginal bleeding and leucorrhea. There was no history of exposure to diethylstilbestrol. Gynecological examination revealed a 7 cm, solid, irregular, polypoid mass in the vagina, based on the anterior lip of the cervix.

Main diagnoses, therapeutic interventions, and results

The tumor was excised in fragments by colposcopy. Histologically it corresponded to a malignant epithelial neoplasm with a tubulocystic pattern, with papillary and solid areas. Composed of clear or hobnail cells, atypical vesicular nuclei and frequent nucleoli. Psammomatous microcalcifications and foci of tumor necrosis were present. Immunoreactivity for PAX8, CKAE1/3AE, EMA, CA-125, CK7, and Napsin-A was present. The diagnosis was clear cell adenocarcinoma.

The patient was treated with radical hysterectomy and is disease-free three years later.

Conclusion

Clear cell adenocarcinoma of the cervix is a rare tumor lacking clear guidelines for effective treatment. The clinical manifestations are basically the same as those of cervical squamous cell carcinoma, and in young patients, they can be confused with dysfunctional uterine bleeding, requiring a correct differential diagnosis. Our patient received primary treatment with colposcopic electrosurgical excision biopsy, followed by radical hysterectomy without chemotherapy or radiation therapy. This could be a new treatment approach for early-stage patients given the positive results observed.

宫颈透明细胞腺癌是一种罕见的组织学变异，通常与宫内暴露于己烯雌酚（DES）有关。主要症状和/或临床表现：15岁女童，处女，阴道出血和白带。没有接触己烯雌酚的历史。妇科检查发现宫颈前唇处，阴道内有一个7厘米的不规则实性息肉样肿块。主要诊断、治疗措施及结果经阴道镜切除肿瘤。组织学上为管状囊样的恶性上皮肿瘤，有乳头状和实性区。由透明或鞋钉状细胞、非典型水泡状细胞核和常见的核仁组成。可见沙粒状微钙化及肿瘤坏死灶。PAX8、CKAE1/3AE、EMA、CA-125、CK7和Napsin-A均有免疫反应性。诊断为透明细胞腺癌。患者接受了根治性子宫切除术，三年后痊愈。结论宫颈透明细胞腺癌是一种罕见的肿瘤，缺乏明确的有效治疗指南。临床表现与宫颈鳞状细胞癌基本相同，年轻患者易与功能失调性子宫出血混淆，需正确鉴别诊断。我们的病人接受了阴道镜电切活检的初步治疗，随后进行了根治性子宫切除术，没有化疗或放疗。鉴于观察到的积极结果，这可能是早期患者的一种新的治疗方法。

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引用次数: 0

Case report of spontaneous hemoperitoneum secondary to uterine myomatosis and adenomyosis 子宫肌瘤病继发自发性腹膜出血1例

IF 0.1 Q4 OBSTETRICS & GYNECOLOGY

Clinica e Investigacion en Ginecologia y Obstetricia

Pub Date : 2025-10-01 Epub Date: 2025-09-04 DOI: 10.1016/j.gine.2025.101066

J.C. Ramírez , K. Cepeda , F. Carmona

Introduction

Myomatosis and uterine adenomyosis are the most common benign uterine pathologies suffered by women of reproductive age and the symptoms they produce are mainly abnormal vaginal bleeding, dysmenorrhea and pelvic pain, but they are rarely associated with spontaneous peritoneal bleeding. The existence of this entity and its etiology is little known in the literature, limited to case reports, generating a difficulty in diagnosis. The objective of this article is to report an infrequent case of spontaneous hemoperitoneum secondary to uterine myomatosis and adenomyosis.

Main symptoms

Prior informed consent and certification from the institution's ethics committee. This is a 50-year-old Colombian patient, in a state of symptomatic perimenopause with hormone replacement therapy, who came to the emergency department with a history of pain in the lower abdomen of three days of severe intensity, only associated with diarrhea.

Main diagnoses

Abdominal computed tomography and transvaginal ultrasound diagnosed hemoperitoneum associated with a probable left adnexal mass, suggestive of a ruptured hemorrhagic cyst.

Therapeutic interventions and results

Exploratory laparoscopy was performed and identify hemoperitoneum secondary to a highly vascularized subserosal fibroid with bleeding from its base, hypervascularized uterus, without obvious ovarian pathology, associated with multiple adhesions between the fibroid, uterine tube and ipsilateral ovary. Due to the patient's age and continuous uncontrolled bleeding, it was decided to perform a total hysterectomy plus unilateral left salpingo-oferectomy.

Conclusion

This case demonstrates that, although extremely rare, uterine fibroids (still coexisting with adenomyosis) can cause spontaneous hemoperitoneum. It is essential to consider this diagnosis within the acute gynecological abdomen, since timely recognition and treatment improve the prognosis.

子宫肌瘤病和子宫血栓是育龄妇女最常见的子宫良性病变，其症状主要为阴道异常出血、痛经和盆腔疼痛，但很少伴有自发性腹膜出血。这种实体的存在及其病因在文献中知之甚少，仅限于病例报告，产生诊断困难。本文的目的是报告一例罕见的自发性腹膜出血继发于子宫肌瘤病和子宫腺肌症。主要症状：事先知情同意并获得机构伦理委员会的认证。这是一名50岁的哥伦比亚患者，处于有症状的围绝经期，接受激素替代治疗，他来到急诊科，有三天的下腹剧烈疼痛史，仅伴有腹泻。主要诊断：腹部计算机断层扫描和经阴道超声诊断腹腔积血可能伴有左附件肿块，提示出血性囊肿破裂。治疗措施及结果：行探查腹腔镜检查，发现浆膜下肌瘤继发于浆膜下肌瘤，其底部出血，子宫血管充血，卵巢无明显病理，肌瘤、输卵管和同侧卵巢之间存在多发粘连。由于患者的年龄和持续不受控制的出血，我们决定进行全子宫切除术加单侧左侧输卵管-子宫切除术。结论本病例表明，虽然极为罕见，但子宫肌瘤（仍与子宫腺肌症共存）可引起自发性腹膜出血。在急腹症中考虑这种诊断是必要的，因为及时识别和治疗可以改善预后。

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引用次数: 0

Relación entre la lactancia materna y las disfunciones sexuales en el posparto. Una revisión sistemática 母乳喂养与产后性功能障碍的关系。系统的审查

IF 0.1 Q4 OBSTETRICS & GYNECOLOGY

Clinica e Investigacion en Ginecologia y Obstetricia

Pub Date : 2025-10-01 Epub Date: 2025-10-06 DOI: 10.1016/j.gine.2025.101067

A. Rodríguez-Alonso , I. Da Cuña-Carrera , A. Alonso-Calvete , L. Núñez-Remiseiro , M. Fernández-Paz

Breastfeeding is defined as the act of transferring milk between mother and child, constituting the ideal and physiological food for neonates. Female sexual dysfunction is established as a disorder of sexual desire, arousal, orgasm and/or sexual pain. The objective of this work is to review and analyze the existing literature to find out if there is a relationship between breastfeeding and the presence of sexual dysfunctions in the postpartum. A bibliographic search was carried out between the months of November and December 2023 in the PubMed, Web of Science (WOS), Scopus, Cochrane Library and Cinahl databases. The descriptors from the Medical Subject Headings (MeSH) thesaurus “Lactation”, “Breast Feeding”, “Postpartum Period”, “Sexual Dysfunction, Physiological” and “Sexual Dysfunctions, Psychological” were used. Articles published in English or Spanish that met the criteria were included. the objective of this review. Of the 123 articles identified, only 9 met the eligibility criteria and were included in the review. Breastfeeding seems to have a relationship with the presence of female sexual dysfunctions in the postpartum, with lower scores being observed in the sexual function questionnaires in lactating women compared to those of non-lactating women. However, it seems difficult to discern between sexual dysfunctions due to breastfeeding and those due to postpartum.

母乳喂养被定义为在母亲和孩子之间传递乳汁的行为，构成了新生儿理想和生理的食物。女性性功能障碍是一种性欲紊乱、性唤起、性高潮和/或性疼痛。本研究的目的是回顾和分析现有文献，以了解母乳喂养与产后出现性功能障碍之间是否存在关系。在2023年11月至12月期间，在PubMed、Web of Science （WOS）、Scopus、Cochrane Library和Cinahl数据库中进行了书目检索。使用医学主题词（MeSH）词库中的描述词“哺乳”、“母乳喂养”、“产后”、“生理性功能障碍”和“心理性功能障碍”。以英语或西班牙语发表的符合标准的文章被包括在内。本综述的目的。在确定的123篇文章中，只有9篇符合资格标准并被纳入审查。母乳喂养似乎与产后女性性功能障碍的存在有关，在性功能问卷调查中，哺乳期妇女的得分低于非哺乳期妇女。但是，很难区分母乳喂养引起的性功能障碍和产后引起的性功能障碍。

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引用次数: 0

Síndrome de hiperestimulación ovárica grave con elevación transitoria de troponina I: a propósito de un caso 严重卵巢过度刺激综合征伴有短暂性肌钙蛋白I升高：以一个病例为例

IF 0.1 Q4 OBSTETRICS & GYNECOLOGY

Clinica e Investigacion en Ginecologia y Obstetricia

Pub Date : 2025-10-01 Epub Date: 2025-10-17 DOI: 10.1016/j.gine.2025.101068

I. Agustí , G. Altinier , G. Casals

Introduction

Ovarian hyperstimulation syndrome (OHSS) is a potentially serious complication of controlled ovarian stimulation, with risk of multi-organ involvement. We present a clinical case of severe OHSS that initially manifested with symptoms suggestive of cardiac involvement and transient troponin elevation, in which cardiac pathology was ultimately ruled out.

Main symptoms and/or clinical findings

A 26-year-old woman, with no cardiovascular history, presented with abdominal distension, nausea, and acute epigastric pain after follicular puncture in the context of controlled ovarian stimulation for egg donation.

Main diagnoses, therapeutic interventions, and outcomes

Severe OHSS was diagnosed with tense ascites, hemoconcentration, altered renal profile, and marked elevation of troponin I (1098 ng/L) and D-dimer. Given the suspicion of myocardial ischemia, cardiological studies were performed, ruling out cardiac pathology. Medical treatment with albumin and diuretics was initiated, with clinical resolution without the need for paracentesis. The patient was discharged after four days, with normalization of laboratory and echocardiographic parameters.

Conclusion

Severe OHSS may present with clinical signs and biomarkers suggestive of cardiac disease. This finding highlights the importance of considering troponin elevation in OHSS within the context of hemodynamic and/or endothelial dysfunction, rather than as a specific marker of myocardial ischemia. This is especially relevant in severe multi-organ clinical presentations where differential diagnosis is crucial.

卵巢过度刺激综合征（OHSS）是控制性卵巢刺激的潜在严重并发症，有累及多器官的风险。我们报告了一例严重的OHSS临床病例，其最初表现为心脏受累和短暂性肌钙蛋白升高的症状，最终排除了心脏病理。1例26岁女性，无心血管病史，在卵泡穿刺后出现腹胀、恶心和急性上腹痛。主要诊断、治疗干预和结果：重度OHSS诊断为腹水紧张、血液浓缩、肾侧改变、肌钙蛋白I （1098 ng/L）和d -二聚体明显升高。考虑到怀疑心肌缺血，进行了心脏学研究，排除了心脏病理学。开始用白蛋白和利尿剂治疗，临床解决不需要穿刺。患者于4天后出院，实验室和超声心动图参数恢复正常。结论重度OHSS可能出现提示心脏疾病的临床体征和生物标志物。这一发现强调了在血液动力学和/或内皮功能障碍的背景下考虑肌钙蛋白升高在OHSS中的重要性，而不是作为心肌缺血的特定标志。这在严重的多器官临床表现中尤其相关，其中鉴别诊断至关重要。

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引用次数: 0

Ablación por radiofrecuencia exitosa de miomas uterinos muy grandes: estudio de 2 casos 成功射频切除非常大的子宫肌瘤：2例研究

IF 0.1 Q4 OBSTETRICS & GYNECOLOGY

Clinica e Investigacion en Ginecologia y Obstetricia

Pub Date : 2025-10-01 Epub Date: 2025-09-02 DOI: 10.1016/j.gine.2025.101065

C. Torrijo Rodrigo, V. Gómez García, C. Giménez Molina

Introduction

Radiofrequency ablation (RFA) is one of the latest minimally invasive treatment options for symptomatic uterine fibroids. The primary goal is to evaluate the feasibility and effectiveness of RFA as a minimally invasive treatment for large uterine fibroids, preserving the uterus and fertility.

Main symptoms and/or clinical findings

Two women, aged 47 and 40, with very large fibroids (approximately 10 cm in length) exhibited symptoms such as hypermenorrhea, urinary symptoms, back pain, and a painful mass.

Main diagnoses, therapeutic interventions, and outcomes

Uterine leiomyomas or fibroids. RFA was performed using a 35 cm monopolar electrode with a 17 gauge and a 10 mm active tip. The sizes of the fibroids were reduced by more than half, and symptoms disappeared after the procedure.

Case 1: A 47-year-old woman with a 10 cm fibroid showed a significant reduction in fibroid size (from 437 to 9 cm³) and complete resolution of symptoms within one year.

Case 2: A 40-year-old woman with a 10.5 cm fibroid experienced a notable reduction in fibroid size (from 472 to 33 cm³) and resolution of symptoms within six months.

Conclusion

These cases demonstrate that RFA is a safe and effective method for treating large uterine fibroids, with significant reductions in fibroid volume and resolution of symptoms. The procedure should be performed by gynecologists experienced in minimally invasive techniques.

射频消融（RFA）是治疗症状性子宫肌瘤的最新微创治疗方法之一。主要目的是评估RFA作为一种微创治疗大子宫肌瘤的可行性和有效性，保留子宫和生育能力。主要症状和/或临床表现2例女性，年龄47岁和40岁，患有超大肌瘤（长约10厘米），表现出痛经、尿路症状、背痛和疼痛肿块等症状。子宫平滑肌瘤或肌瘤的主要诊断、治疗措施及结果。RFA使用35 cm单极电极，17 gauge和10 mm有源尖端。肌瘤的大小缩小了一半以上，手术后症状消失。病例1：一名47岁女性，肌瘤为10厘米，肌瘤大小明显减小（从437厘米减小到9厘米），一年内症状完全缓解。病例2：一名患有10.5 cm肌瘤的40岁女性在6个月内肌瘤大小明显减小（从472减小到33 cm3），症状得到缓解。结论RFA是一种安全有效的治疗大肌瘤的方法，肌瘤体积明显缩小，症状明显缓解。手术应由具有微创技术经验的妇科医生进行。

{"title":"Ablación por radiofrecuencia exitosa de miomas uterinos muy grandes: estudio de 2 casos","authors":"C. Torrijo Rodrigo, V. Gómez García, C. Giménez Molina","doi":"10.1016/j.gine.2025.101065","DOIUrl":"10.1016/j.gine.2025.101065","url":null,"abstract":"<div><h3>Introduction</h3><div>Radiofrequency ablation (RFA) is one of the latest minimally invasive treatment options for symptomatic uterine fibroids. The primary goal is to evaluate the feasibility and effectiveness of RFA as a minimally invasive treatment for large uterine fibroids, preserving the uterus and fertility.</div></div><div><h3>Main symptoms and/or clinical findings</h3><div>Two women, aged 47 and 40, with very large fibroids (approximately 10cm in length) exhibited symptoms such as hypermenorrhea, urinary symptoms, back pain, and a painful mass.</div></div><div><h3>Main diagnoses, therapeutic interventions, and outcomes</h3><div>Uterine leiomyomas or fibroids. RFA was performed using a 35cm monopolar electrode with a 17 gauge and a 10mm active tip. The sizes of the fibroids were reduced by more than half, and symptoms disappeared after the procedure.</div><div>Case 1: A 47-year-old woman with a 10cm fibroid showed a significant reduction in fibroid size (from 437 to 9cm<sup>3</sup>) and complete resolution of symptoms within one year.</div><div>Case 2: A 40-year-old woman with a 10.5cm fibroid experienced a notable reduction in fibroid size (from 472 to 33cm<sup>3</sup>) and resolution of symptoms within six months.</div></div><div><h3>Conclusion</h3><div>These cases demonstrate that RFA is a safe and effective method for treating large uterine fibroids, with significant reductions in fibroid volume and resolution of symptoms. The procedure should be performed by gynecologists experienced in minimally invasive techniques.</div></div>","PeriodicalId":41294,"journal":{"name":"Clinica e Investigacion en Ginecologia y Obstetricia","volume":"52 4","pages":"Article 101065"},"PeriodicalIF":0.1,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144925251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Premature ovarian insufficiency: An update. A literature review 卵巢早衰：最新进展。文献综述

IF 0.1 Q4 OBSTETRICS & GYNECOLOGY

Clinica e Investigacion en Ginecologia y Obstetricia

Pub Date : 2025-10-01 Epub Date: 2025-11-11 DOI: 10.1016/j.gine.2025.101071

M.M.A. Abdelhafez , K.A.M. Ahmed , N.A.M. Ahmed , M.H. Ismail , M.N. Bin Mohd Daud , A.M. Eldiasty , M.F. Bin Amri , M.S. Jeffree , F. Kadir , D.M. Pg Baharuddin , M.F. Bin Bolong , F. Hayati , N.B. Azizan , D. Sumpat , S.S. Syed Abdul Rahim , W.W. Than , M. Yusof Ibrahim , L. Zhen Zhen , M. Zoe Soe

Premature ovarian insufficiency is defined as the loss of ovarian function before the age of 40. It is linked to hypoestrogenism and the loss of remaining follicles, which causes irregular menstruation, infertility, and a decline in health-related quality of life. This article goal is to highlight and analyse the various contemporary strategies for the diagnosis and treatment of the disease with reference to the most recent and evidence-based interventions in this context. A comprehensive review of the literature was conducted using database searches in EMBASE, Science Direct, Google Scholar, Scopus, and PubMed to obtain the objectives and aim of the study. The results of the search found that menopause affects about 5% of women between the ages of 40 and 45, while it affects about 1% of women before the age of 40. Under the age of 30, the disease affects about 1 in 1000 women, sometimes as early as adolescence. Our study concluded that: premature ovarian insufficiency is a condition of oestrogen deficiency that has both immediate and long-term effects on health and mental well-being. The physical, psychological, and emotional difficulties brought on by the disease's diagnosis must be handled, and the short- and long-term wellness of these young women must be safeguarded, by healthcare professionals managing these complicated entities successfully.

卵巢功能不全被定义为40岁之前卵巢功能丧失。它与雌激素水平低下和剩余卵泡的丧失有关，这导致月经不调、不孕症和与健康相关的生活质量下降。这篇文章的目的是强调和分析各种当代战略的诊断和治疗的疾病，参考最新的证据为基础的干预措施在这方面。通过EMBASE、Science Direct、b谷歌Scholar、Scopus和PubMed等数据库检索，对文献进行了全面的综述，以获得本研究的目标和目的。研究结果发现，在40岁至45岁的女性中，更年期影响约5%，而在40岁之前的女性中，更年期影响约1%。在30岁以下的女性中，每1000名女性中就有1人患此病，有时早在青春期就会发病。我们的研究得出结论：卵巢功能不全是一种雌激素缺乏的情况，对健康和精神健康有直接和长期的影响。必须处理由疾病诊断带来的身体、心理和情感上的困难，这些年轻妇女的短期和长期健康必须得到保健专业人员的保护，成功地管理这些复杂的实体。

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引用次数: 0

Abdominal access following insufflation with Veress needle at high pressure: A security maneuver for the reduction of surgical complications during laparoscopic access 在高压下用Veress针注入腹部通路：在腹腔镜通路中减少手术并发症的安全操作

IF 0.1 Q4 OBSTETRICS & GYNECOLOGY

Clinica e Investigacion en Ginecologia y Obstetricia

Pub Date : 2025-07-01 Epub Date: 2025-05-09 DOI: 10.1016/j.gine.2025.101051

F. Palomo-Rodriguez , J. Gallardo-Martinez , R.D. Brenner-Anidjar , Z. Frias-Sanchez , S. Rojo-Novo , M. Pantoja-Garrido , F.J. Pantoja-Rosso , J.J. Fernandez-Alba

Introduction

Up to 50% of laparoscopic complications arise during access maneuvers to abdominal cavity. Our aim is to determine whether elevated pressures of 20–25 mmHg during these maneuvers, by increasing the distance between the abdominal wall and intracavitary organs, can help reduce the risk of entry-related complications, without an increase in anesthetic adverse effects.

Methods and materials

Prospective observational analytic multi-centered cohort study with 703 patients. The exposed-cohort consisted of patients undergoing gynecological laparoscopic surgeries in which an intra-abdominal pressure of 20–25 mmHg was used (group 20–25 mmHg) as opposed to the unexposed-cohort, in which usual < 15 mmHg pressures (group < 15 mmHg) were used. All surgeries were performed using the Veress needle as the method of insufflation.

Results

Patients in whom access was performed at pressures < 15 mmHg had a higher risk of complications than those in whom elevated pressures of 20–25 mmHg were used, which was statistically significant (OR 3.08, 95% CI95% 1.42–6.65, p = 0.004), without finding differences regarding anesthetic complications (p = 0.9).

Conclusion

The use of high intraabdominal pressure during access maneuvers serves as an effective technique for the prevention of complications, especially major complications, when compared with standard-used pressures, without increasing the incidence of anesthetic adverse effects, due to their temporary maintenance.

高达50%的腹腔镜并发症发生在进入腹腔的过程中。我们的目的是确定在这些操作中，通过增加腹壁和腔内器官之间的距离，将压力升高20-25 mmHg是否有助于减少与进入相关的并发症的风险，而不会增加麻醉剂的不良反应。方法与材料703例患者的前瞻性观察分析多中心队列研究。暴露队列由接受妇科腹腔镜手术的患者组成，其中使用20-25 mmHg的腹内压（20-25 mmHg组）与未暴露队列相反，其中通常使用<；15毫米汞柱压力(组<；15 mmHg)。所有手术均采用Veress针作为充气方法。结果在压力下进行访问的患者；15 mmHg组的并发症风险高于20-25 mmHg组，差异有统计学意义（OR 3.08, 95% CI95% 1.42-6.65, p = 0.004），麻醉并发症无差异（p = 0.9）。结论与标准压力相比，使用高腹内压可有效预防并发症，特别是主要并发症的发生，且由于其暂时性维持，不会增加麻醉不良反应的发生率。

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引用次数: 0

Radiofrequency treatment value for uterine fibroids in pregnant and infertile women 妊娠和不孕症妇女子宫肌瘤的射频治疗价值

IF 0.1 Q4 OBSTETRICS & GYNECOLOGY

Clinica e Investigacion en Ginecologia y Obstetricia

Pub Date : 2025-07-01 Epub Date: 2025-05-13 DOI: 10.1016/j.gine.2025.101052

M. Bonet-Sánchez , I. Pelayo-Delgado

Radiofrequency ablation of uterine fibroids is a technique based on the application of a high-frequency electrical current, causing a coagulative necrosis of the fibroid. The aim of this review is to analyse the influence of radiofrequency treatment of fibroids in women with gestational desire and its influence on pregnancy, through the compilation and study of recent articles. Radiofrequency has achieved a similar number of full-term births compared to that of surgical myomectomy, which until now has been the gold standard treatment for women with myomas desiring pregnancy. It also seems to increase obstetric security in pregnant women previously treated compared to other techniques, with fewer rate of preterm deliveries, spontaneous abortions and placental changes. However, more randomized clinical trials focusing specifically on pregnancy are necessary to reach definitive conclusions.

子宫肌瘤的射频消融是一种基于高频电流应用的技术，引起肌瘤的凝固性坏死。本综述的目的是通过对近期文章的汇编和研究，分析射频治疗子宫肌瘤对妊娠的影响及其对妊娠的影响。与手术子宫肌瘤切除术相比，射频治疗的足月分娩数量与手术子宫肌瘤切除术相似，到目前为止，子宫肌瘤切除术一直是希望怀孕的子宫肌瘤妇女的黄金标准治疗方法。与其他技术相比，它似乎也增加了以前接受过治疗的孕妇的产科安全性，早产、自然流产和胎盘改变的发生率更低。然而，需要更多针对妊娠的随机临床试验来得出明确的结论。

引用次数: 0

Impact of deep endometriosis with and without ovarian involvement on quality of life compared to exclusive ovarian endometriosis 与排他性卵巢子宫内膜异位症相比，伴有和不伴有卵巢受累的深部子宫内膜异位症对生活质量的影响

IF 0.1 Q4 OBSTETRICS & GYNECOLOGY

Clinica e Investigacion en Ginecologia y Obstetricia

Pub Date : 2025-07-01 Epub Date: 2025-05-10 DOI: 10.1016/j.gine.2025.101053

M.d.P. Marín Sánchez , M. Martínez-Esparza , P. García-Peñarrubia , A.J. Ruiz-Alcaraz , J.J. Arense-Gonzálo

Objective

To evaluate potential differences in quality of life between patients with deep endometriosis, with or without ovarian involvement (DE), and those with exclusive ovarian endometriosis (OMA).

Material and method

A prospective observational study was conducted on patients diagnosed with endometriosis through clinical assessment and imaging techniques, or histological confirmation. Patients were labeled as OMA or DE. Clinical data such as pain (visual analogue scale), demographic and anthropometric data, and QoL (SF-12v2 scale) were evaluated. Statistical analysis was performed using IBM SPSS 25.0.

Results

A total of 307 patients were enrolled, 109 with OMA and 198 with DE. Patients with OMA were younger than those with DE. QoL in the physical domain was lower in DE compared to OMA (46 ± 11.91 vs 49.9 ± 9.4; p < 0.02). No statistically significant differences were observed in the mental domain (41.5 ± 10.2 vs 42.8 ± 11; p < 0.276). Pain scores on the visual analogue scale did not differ significantly between groups. However, in the pain domain of the SF-12v2 scale, significant differences were found, with lower scores in DE (61.4 ± 32.7 vs 73.6 ± 28.6; p < 0.001).

Conclusion

QoL scales should be utilized in clinical practice as they provide valuable insights into how the disease impacts patients’ lives. Patients with deep endometriosis have a poorer QoL in the physical domain compared to those with exclusive ovarian endometriosis.

目的评价深部子宫内膜异位症伴或不伴卵巢受累（DE）患者与排他性卵巢子宫内膜异位症（OMA）患者生活质量的潜在差异。材料与方法对经临床评估、影像学检查或组织学证实的子宫内膜异位症患者进行前瞻性观察研究。将患者标记为OMA或DE。评估临床数据，如疼痛（视觉模拟量表）、人口统计学和人体测量数据以及生活质量（SF-12v2量表）。采用IBM SPSS 25.0进行统计学分析。结果共纳入307例患者，其中OMA患者109例，DE患者198例，OMA患者年龄小于DE患者，DE患者的生理生活质量低于OMA患者(46±11.91 vs 49.9±9.4；p & lt;0.02)。两组在心理领域的差异无统计学意义(41.5±10.2 vs 42.8±11；p & lt;0.276)。视觉模拟量表疼痛评分组间无显著差异。然而，在SF-12v2量表的疼痛域，发现有显著差异，DE得分较低(61.4±32.7 vs 73.6±28.6；p & lt;0.001)。结论生活质量量表对疾病如何影响患者生活提供了有价值的见解，值得在临床实践中使用。与排他性卵巢子宫内膜异位症患者相比，深部子宫内膜异位症患者在物理领域的生活质量较差。

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引用次数: 0

Investigating the impact of sleep disorders on intracytoplasmic sperm injection outcome: A prospective observational study 研究睡眠障碍对卵胞浆内单精子注射结果的影响：一项前瞻性观察研究

IF 0.1 Q4 OBSTETRICS & GYNECOLOGY

Clinica e Investigacion en Ginecologia y Obstetricia

Pub Date : 2025-07-01 Epub Date: 2025-04-11 DOI: 10.1016/j.gine.2025.101034

M.K. Abd El-Haseeb, O.A. Soliman Sallam, M.S. Abd El-Hamed

Background

The relationship between sleep quality and outcomes of assisted reproductive technologies (ART), particularly intracytoplasmic sperm injection (ICSI), remains relatively unexplored. Understanding this association is crucial for optimizing fertility treatments and improving success rates. This study aimed to investigate the impact of sleep quality on ICSI outcomes and explore potential correlations with various variables.

Methods

A prospective observational study was conducted on 150 infertile couples undergoing ICSI treatment. Demographic, clinical, and sleep quality data were collected. Statistical analyses, including Spearman's correlation and multiple linear regression, were performed to assess the relationships between sleep quality, treatment variables, and outcomes.

Results

The mean age of participants was 32.71 years, with a majority residing in rural areas. No significant differences were found in pregnancy rates or embryo characteristics across different sleep quality groups. However, moderate positive correlations were observed between sleep quality scores and fertilization rates (p < 0.05).

Conclusion

While sleep quality did not significantly impact ICSI outcomes in this study, moderate correlations were found with fertilization rates. Further research is needed to elucidate the complex interplay between sleep quality, reproductive treatments, and outcomes to optimize fertility care.

背景睡眠质量与辅助生殖技术（ART），尤其是卵胞浆内单精子显微注射（ICSI）的结果之间的关系尚未得到深入研究。了解这种关系对于优化生育治疗和提高成功率至关重要。本研究旨在调查睡眠质量对卵胞浆内单精子显微注射（ICSI）结果的影响，并探讨其与各种变量之间的潜在关联。研究收集了人口统计学、临床和睡眠质量数据。结果参与者的平均年龄为 32.71 岁，大多数居住在农村地区。不同睡眠质量组的怀孕率和胚胎特征无明显差异。结论在这项研究中，虽然睡眠质量对卵胞浆内单精子显微注射的结果没有显著影响，但与受精率有一定的相关性。需要进一步研究阐明睡眠质量、生殖治疗和结果之间复杂的相互作用，以优化生育护理。

{"title":"Investigating the impact of sleep disorders on intracytoplasmic sperm injection outcome: A prospective observational study","authors":"M.K. Abd El-Haseeb, O.A. Soliman Sallam, M.S. Abd El-Hamed","doi":"10.1016/j.gine.2025.101034","DOIUrl":"10.1016/j.gine.2025.101034","url":null,"abstract":"<div><h3>Background</h3><div>The relationship between sleep quality and outcomes of assisted reproductive technologies (ART), particularly intracytoplasmic sperm injection (ICSI), remains relatively unexplored. Understanding this association is crucial for optimizing fertility treatments and improving success rates. This study aimed to investigate the impact of sleep quality on ICSI outcomes and explore potential correlations with various variables.</div></div><div><h3>Methods</h3><div>A prospective observational study was conducted on 150 infertile couples undergoing ICSI treatment. Demographic, clinical, and sleep quality data were collected. Statistical analyses, including Spearman's correlation and multiple linear regression, were performed to assess the relationships between sleep quality, treatment variables, and outcomes.</div></div><div><h3>Results</h3><div>The mean age of participants was 32.71 years, with a majority residing in rural areas. No significant differences were found in pregnancy rates or embryo characteristics across different sleep quality groups. However, moderate positive correlations were observed between sleep quality scores and fertilization rates (<em>p</em>  <!-->0.05).</div></div><div><h3>Conclusion</h3><div>While sleep quality did not significantly impact ICSI outcomes in this study, moderate correlations were found with fertilization rates. Further research is needed to elucidate the complex interplay between sleep quality, reproductive treatments, and outcomes to optimize fertility care.</div></div>","PeriodicalId":41294,"journal":{"name":"Clinica e Investigacion en Ginecologia y Obstetricia","volume":"52 3","pages":"Article 101034"},"PeriodicalIF":0.1,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143815340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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