首页 > 最新文献

Paediatric Nephrology最新文献

英文 中文
Drug prescribing 药物处方
Pub Date : 2019-02-01 DOI: 10.1093/med/9780198784272.003.0022
L. Rees, N. Webb, D. Bockenhauer, M. Punaro
Great care should be exercised when prescribing for children with kidney disease. Many drugs are renally excreted and require dose adjustment in the presence of chronic kidney disease. Children with kidney disease, particularly those who have undergone kidney transplantation, frequently receive a large number of drugs and there is significant potential for drug–drug interaction. Information is available in the British National Formulary for Children and other texts; however, advice from an experienced paediatric nephrologist or specialist renal pharmacist should be sought where there is uncertainty.
在给患有肾脏疾病的儿童开处方时,应该非常小心。许多药物是肾脏排泄的,在存在慢性肾脏疾病时需要调整剂量。患有肾脏疾病的儿童,特别是那些接受过肾移植的儿童,经常接受大量药物治疗,并且存在很大的药物相互作用的可能性。英国国家儿童处方集和其他文本提供了相关信息;然而,从经验丰富的儿科肾病专家或专业肾脏药剂师的建议,应寻求有不确定性。
{"title":"Drug prescribing","authors":"L. Rees, N. Webb, D. Bockenhauer, M. Punaro","doi":"10.1093/med/9780198784272.003.0022","DOIUrl":"https://doi.org/10.1093/med/9780198784272.003.0022","url":null,"abstract":"Great care should be exercised when prescribing for children with kidney disease. Many drugs are renally excreted and require dose adjustment in the presence of chronic kidney disease. Children with kidney disease, particularly those who have undergone kidney transplantation, frequently receive a large number of drugs and there is significant potential for drug–drug interaction. Information is available in the British National Formulary for Children and other texts; however, advice from an experienced paediatric nephrologist or specialist renal pharmacist should be sought where there is uncertainty.","PeriodicalId":415366,"journal":{"name":"Paediatric Nephrology","volume":"697 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122982903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Chronic kidney disease 慢性肾病
Pub Date : 2019-02-01 DOI: 10.1093/med/9780198784272.003.0018
L. Rees, N. Webb, D. Bockenhauer, M. Punaro
This chapter discusses all aspects of chronic kidney disease in childhood.
本章讨论儿童慢性肾脏疾病的各个方面。
{"title":"Chronic kidney disease","authors":"L. Rees, N. Webb, D. Bockenhauer, M. Punaro","doi":"10.1093/med/9780198784272.003.0018","DOIUrl":"https://doi.org/10.1093/med/9780198784272.003.0018","url":null,"abstract":"This chapter discusses all aspects of chronic kidney disease in childhood.","PeriodicalId":415366,"journal":{"name":"Paediatric Nephrology","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133179608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Peritoneal dialysis in end-stage kidney disease 腹膜透析治疗终末期肾病
Pub Date : 2019-02-01 DOI: 10.1093/med/9780198784272.003.0019
L. Rees, N. Webb, D. Bockenhauer, M. Punaro
This chapter describes the principles of peritoneal dialysis, the insertion of the peritoneal dialysis catheter, prevention and treatment of infection, the peritoneal dialysis prescription, and assessment of the dialysis provision.
本章介绍腹膜透析的原理、腹膜透析导管的插入、感染的预防和治疗、腹膜透析处方以及透析提供的评估。
{"title":"Peritoneal dialysis in end-stage kidney disease","authors":"L. Rees, N. Webb, D. Bockenhauer, M. Punaro","doi":"10.1093/med/9780198784272.003.0019","DOIUrl":"https://doi.org/10.1093/med/9780198784272.003.0019","url":null,"abstract":"This chapter describes the principles of peritoneal dialysis, the insertion of the peritoneal dialysis catheter, prevention and treatment of infection, the peritoneal dialysis prescription, and assessment of the dialysis provision.","PeriodicalId":415366,"journal":{"name":"Paediatric Nephrology","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115358310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Extracorporeal treatment 体外治疗
Pub Date : 2019-02-01 DOI: 10.1093/med/9780198784272.003.0020
L. Rees, N. Webb, D. Bockenhauer, M. Punaro
This chapter focuses on all aspects of haemodialysis: the principles, including vascular access; the machine, dialysate, and water; the prescription; complications; assessment of adequacy; and blood-borne viruses. Continuous renal replacement therapy, plasmapheresis, and immunoadsorption are also discussed.
本章重点介绍血液透析的各个方面:原理,包括血管通路;机器、透析液、水;处方;并发症;评估充分性;还有血液传播的病毒。持续肾替代治疗,血浆置换和免疫吸附也进行了讨论。
{"title":"Extracorporeal treatment","authors":"L. Rees, N. Webb, D. Bockenhauer, M. Punaro","doi":"10.1093/med/9780198784272.003.0020","DOIUrl":"https://doi.org/10.1093/med/9780198784272.003.0020","url":null,"abstract":"This chapter focuses on all aspects of haemodialysis: the principles, including vascular access; the machine, dialysate, and water; the prescription; complications; assessment of adequacy; and blood-borne viruses. Continuous renal replacement therapy, plasmapheresis, and immunoadsorption are also discussed.","PeriodicalId":415366,"journal":{"name":"Paediatric Nephrology","volume":"53 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122725174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Congenital abnormalities of the kidneys and urinary tract 肾脏和泌尿道的先天性畸形
Pub Date : 2019-02-01 DOI: 10.1093/med/9780198784272.003.0003
L. Rees, N. Webb, D. Bockenhauer, M. Punaro
Congenital abnormalities of the kidneys and urinary tract (CAKUT) are the commonest cause of renal problems in children, ranging from asymptomatic or incidental findings to a cause of urinary tract infection and obstruction, renal damage, and end-stage kidney disease. The investigation and management of CAKUT depend on the potential for causing renal injury.
先天性肾脏和尿路异常(CAKUT)是儿童肾脏问题最常见的原因,从无症状或偶然发现到尿路感染和梗阻、肾脏损害和终末期肾脏疾病。CAKUT的调查和治疗取决于是否有可能引起肾脏损伤。
{"title":"Congenital abnormalities of the kidneys and urinary tract","authors":"L. Rees, N. Webb, D. Bockenhauer, M. Punaro","doi":"10.1093/med/9780198784272.003.0003","DOIUrl":"https://doi.org/10.1093/med/9780198784272.003.0003","url":null,"abstract":"Congenital abnormalities of the kidneys and urinary tract (CAKUT) are the commonest cause of renal problems in children, ranging from asymptomatic or incidental findings to a cause of urinary tract infection and obstruction, renal damage, and end-stage kidney disease. The investigation and management of CAKUT depend on the potential for causing renal injury.","PeriodicalId":415366,"journal":{"name":"Paediatric Nephrology","volume":"55 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132135823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Vasculitis 血管炎
Pub Date : 2019-02-01 DOI: 10.1093/med/9780198784272.003.0011
L. Rees, N. Webb, D. Bockenhauer, M. Punaro
This chapter describes the presentation, investigation, and management of children with vasculitis.
本章描述了儿童血管炎的表现、调查和处理。
{"title":"Vasculitis","authors":"L. Rees, N. Webb, D. Bockenhauer, M. Punaro","doi":"10.1093/med/9780198784272.003.0011","DOIUrl":"https://doi.org/10.1093/med/9780198784272.003.0011","url":null,"abstract":"This chapter describes the presentation, investigation, and management of children with vasculitis.","PeriodicalId":415366,"journal":{"name":"Paediatric Nephrology","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134053955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Infections and the kidney 感染和肾脏
Pub Date : 2012-03-01 DOI: 10.1093/MED/9780198784272.003.0012
L. Rees, N. Webb, D. Bockenhauer, M. Punaro
Many infections can affect the kidney, either by direct invasion or by immune mechanisms. This chapter describes the commoner infections.
许多感染可以通过直接侵入或免疫机制影响肾脏。本章描述了常见的感染。
{"title":"Infections and the kidney","authors":"L. Rees, N. Webb, D. Bockenhauer, M. Punaro","doi":"10.1093/MED/9780198784272.003.0012","DOIUrl":"https://doi.org/10.1093/MED/9780198784272.003.0012","url":null,"abstract":"Many infections can affect the kidney, either by direct invasion or by immune mechanisms. This chapter describes the commoner infections.","PeriodicalId":415366,"journal":{"name":"Paediatric Nephrology","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116401742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Renal calculi and nephrocalcinosis 肾结石和肾钙质沉着症
Pub Date : 2012-03-01 DOI: 10.1093/MED/9780198784272.003.0008
L. Rees, N. Webb, D. Bockenhauer, M. Punaro
Urolithiasis and nephrocalcinosis can be associated with substantial morbidity: stones can lead to obstruction and/or infection, which can lead to loss of kidney function, if not treated promptly. Nephrocalcinosis is often associated with a urinary concentrating defect, predisposing to dehydration. This chapter discusses the underlying causes of renal calculi and nephrocalcinosis, their diagnosis, and the acute and chronic management.
尿石症和肾钙质沉着症可能与大量发病率相关:结石可导致阻塞和/或感染,如果不及时治疗,可导致肾功能丧失。肾钙质沉着症常与尿浓缩缺陷有关,易导致脱水。本章讨论肾结石和肾钙质沉着症的潜在原因,他们的诊断,以及急性和慢性管理。
{"title":"Renal calculi and nephrocalcinosis","authors":"L. Rees, N. Webb, D. Bockenhauer, M. Punaro","doi":"10.1093/MED/9780198784272.003.0008","DOIUrl":"https://doi.org/10.1093/MED/9780198784272.003.0008","url":null,"abstract":"Urolithiasis and nephrocalcinosis can be associated with substantial morbidity: stones can lead to obstruction and/or infection, which can lead to loss of kidney function, if not treated promptly. Nephrocalcinosis is often associated with a urinary concentrating defect, predisposing to dehydration. This chapter discusses the underlying causes of renal calculi and nephrocalcinosis, their diagnosis, and the acute and chronic management.","PeriodicalId":415366,"journal":{"name":"Paediatric Nephrology","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123822438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Renal cystic diseases and ciliopathies 肾囊性疾病和纤毛病
Pub Date : 2012-03-01 DOI: 10.1093/med/9780198784272.003.0013
L. Rees, N. Webb, D. Bockenhauer, M. Punaro
Inherited renal cystic diseases comprise a spectrum of disorders that are typically characterized by dysfunction of the so-called cilia. These hair-like cellular appendages are involved in numerous cellular signalling processes. During development, cilia are important for the development of the left–right axis and for the establishment of cell polarity. Consequently, depending on the specific nature of the underlying ciliary defect, renal cystic diseases can be associated with a large spectrum of other organ manifestations, including congenital heart disease, retinopathy, polydactyly, and hepatic abnormalities, such as ductal plate malformation. Based on clustering of such symptoms, specific clinical syndromes, such as nephronophthisis, Bardet–Biedl syndrome, Joubert syndrome, and the various forms of polycystic kidney diseases, have been assigned. Subsequent genetic investigations have shown that these clinical distinctions are not necessarily consistent with the underlying genetic alterations, so that, for example, genes initially associated with Joubert syndrome can phenocopy autosomal recessive polycystic kidney disease. Thus, identification of the genetic cause can inform the clinical management to assess for potentially involved organ manifestations.
遗传性肾囊性疾病包括一系列疾病,其典型特征是所谓的纤毛功能障碍。这些毛发状的细胞附属物参与了许多细胞信号传递过程。在发育过程中,纤毛对左右轴的发育和细胞极性的建立起着重要的作用。因此,根据潜在纤毛缺陷的具体性质,肾囊性疾病可与多种其他器官表现相关,包括先天性心脏病、视网膜病变、多指畸形和肝脏异常,如导管板畸形。根据这些症状的聚类,指定了具体的临床综合征,如肾肾病、Bardet-Biedl综合征、Joubert综合征和各种形式的多囊肾病。随后的遗传学研究表明,这些临床差异并不一定与潜在的遗传改变相一致,因此,例如,最初与Joubert综合征相关的基因可能表现为常染色体隐性多囊肾病。因此,确定遗传原因可以告知临床管理评估潜在累及的器官表现。
{"title":"Renal cystic diseases and ciliopathies","authors":"L. Rees, N. Webb, D. Bockenhauer, M. Punaro","doi":"10.1093/med/9780198784272.003.0013","DOIUrl":"https://doi.org/10.1093/med/9780198784272.003.0013","url":null,"abstract":"Inherited renal cystic diseases comprise a spectrum of disorders that are typically characterized by dysfunction of the so-called cilia. These hair-like cellular appendages are involved in numerous cellular signalling processes. During development, cilia are important for the development of the left–right axis and for the establishment of cell polarity. Consequently, depending on the specific nature of the underlying ciliary defect, renal cystic diseases can be associated with a large spectrum of other organ manifestations, including congenital heart disease, retinopathy, polydactyly, and hepatic abnormalities, such as ductal plate malformation. Based on clustering of such symptoms, specific clinical syndromes, such as nephronophthisis, Bardet–Biedl syndrome, Joubert syndrome, and the various forms of polycystic kidney diseases, have been assigned. Subsequent genetic investigations have shown that these clinical distinctions are not necessarily consistent with the underlying genetic alterations, so that, for example, genes initially associated with Joubert syndrome can phenocopy autosomal recessive polycystic kidney disease. Thus, identification of the genetic cause can inform the clinical management to assess for potentially involved organ manifestations.","PeriodicalId":415366,"journal":{"name":"Paediatric Nephrology","volume":"05 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127194814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Systemic disease affecting the kidney 肾病影响肾脏的全身性疾病
Pub Date : 2012-03-01 DOI: 10.1093/med/9780198784272.003.0010
L. Rees, N. Webb, D. Bockenhauer, M. Punaro
Many systemic diseases affect the kidney. This chapter describes the most common and significant ones.
许多全身性疾病影响肾脏。本章描述了最常见和最重要的几种。
{"title":"Systemic disease affecting the kidney","authors":"L. Rees, N. Webb, D. Bockenhauer, M. Punaro","doi":"10.1093/med/9780198784272.003.0010","DOIUrl":"https://doi.org/10.1093/med/9780198784272.003.0010","url":null,"abstract":"Many systemic diseases affect the kidney. This chapter describes the most common and significant ones.","PeriodicalId":415366,"journal":{"name":"Paediatric Nephrology","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132849308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Paediatric Nephrology
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1