Beata Radzymińska-Chruściel, Urszula Dajda, Sebastian Zalewski, A. Piatkowska, Julia Wieczor, Dariusz Gołąbek, D. Porada, A. Rudziński
Abstract This is case report of extremely rare mosaic trisomy of 16th pair of chromosomes from the high risk pregnancy (maternal age 35 years old, positive screeining in 1st trimester). The fetus presented with intrauterine growth retardation, congenital heart defect, dysmorphic features and skeletal anomalies. The case has been observed until hospitalization in pediatric cardiology department. Other similar cases have been analysed.
{"title":"Mosaicism of Trisomy of 16 Pairs of Chromosomes with Partial Situs Inversus and Levocardia Observation of Extremely Rare Anomaly from 1st Trimester to Neonatal Period- Case Report","authors":"Beata Radzymińska-Chruściel, Urszula Dajda, Sebastian Zalewski, A. Piatkowska, Julia Wieczor, Dariusz Gołąbek, D. Porada, A. Rudziński","doi":"10.12847/03136","DOIUrl":"https://doi.org/10.12847/03136","url":null,"abstract":"Abstract This is case report of extremely rare mosaic trisomy of 16th pair of chromosomes from the high risk pregnancy (maternal age 35 years old, positive screeining in 1st trimester). The fetus presented with intrauterine growth retardation, congenital heart defect, dysmorphic features and skeletal anomalies. The case has been observed until hospitalization in pediatric cardiology department. Other similar cases have been analysed.","PeriodicalId":415760,"journal":{"name":"Prenatal Cardiology","volume":"264 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125810758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Echocardiographic prenatal diagnosis is an important and increasingly popular method available for the diagnosis of birth defects and heart disease in children. It is particularly important in fetuses with complex defects requiring urgent surgery after birth and / or intervention. Prior information about such cases allows mothers to be referred for delivery to maternity centers which will secure pre-treatment and efficient transfer of the newborn to the closest possible pediatric cardiac and cardiothoracic surgery center.
{"title":"Anomalous Pulmonary Venous Return with Stenosis in Complex Left Heart Defect – Lethal Anomaly – Description of 3 Cases","authors":"A. Rudziński","doi":"10.1515/pcard-2015-0009","DOIUrl":"https://doi.org/10.1515/pcard-2015-0009","url":null,"abstract":"Echocardiographic prenatal diagnosis is an important and increasingly popular method available for the diagnosis of birth defects and heart disease in children. It is particularly important in fetuses with complex defects requiring urgent surgery after birth and / or intervention. Prior information about such cases allows mothers to be referred for delivery to maternity centers which will secure pre-treatment and efficient transfer of the newborn to the closest possible pediatric cardiac and cardiothoracic surgery center.","PeriodicalId":415760,"journal":{"name":"Prenatal Cardiology","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126519150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Słodki, J. Szymkiewicz-Dangel, A. Włoch, A. Siwińska, Beata Radzymińska-Chruściel, M. Respondek-Liberska
Abstract The Polish National Registry for Fetal Cardiac Pathology, which has been in existence since 2004, is one of the unique organisational achievements of the Polish prenatal cardiology. Now that the calendar year 2012 is over, we are setting about working on the summary of our work to chart its new directions. Materials and methods: Standard data reports from the year 2012 have been analysed and compared with data published in the Prenatal Cardiology quarterly in 2011 and other data collected between 2004 and 2010. Results: 538 new records were entered in the Registry in 2012. Consequently, the total number of examinations registered between 2004 and 2012 amounts to 5297 records. 72% (n = 388) of all the patients entered in the Registry were examined by C-type centres, i.e. Warsaw (186), Łódź (150) and Ruda Śląska (79). The commonest heart defects included hypoplastic left heart syndrome (n = 81), tetralogy of Fallot (n = 51) and AVSD (n = 49): atrial & ventricular components (n = 49). The data collected between 2004 and 2010, in 2011 and 2012 were compared. In 2011 544 foetuses with cardiologic problems were registered, while in 2012 there were 538 of them. In 2011, there were 24 centres in the Registry. Last year, there were 27 of them. As in the previous years, HLHS was the most frequently registered foetus heart defect in 2012. In 2012 the second one was TOF. In 2012, LSF and PBU were the two major prenatal cardiology centres in Poland and registered over 100 foetuses every year. In 2012, the number of doctors diagnosing over five cases of foetal heart defects a year reached 10%. The majority of the doctors (89%) diagnosed such cases rarely (< 5 cases a year). In 2011, the percentage of the pregnant women who decided to terminate the pregnancy was larger than between 2004 and 2010, but smaller than in 2012; it was < 7%. Conclusions: The data included in the 2012 in The Polish National Registry for Fetal Cardiac Pathology is similar to the data collected in the previous years. The classification of foetal heart defects is imperfect and interpreted in various ways by particular centres. This needs to be changed in the future; the way the classification is interpreted must be made uniform.
{"title":"Selected Data from the Polish National Registry for Fetal Cardiac Pathology for the Year 2012 – Quo Vadis?","authors":"M. Słodki, J. Szymkiewicz-Dangel, A. Włoch, A. Siwińska, Beata Radzymińska-Chruściel, M. Respondek-Liberska","doi":"10.12847/03131","DOIUrl":"https://doi.org/10.12847/03131","url":null,"abstract":"Abstract The Polish National Registry for Fetal Cardiac Pathology, which has been in existence since 2004, is one of the unique organisational achievements of the Polish prenatal cardiology. Now that the calendar year 2012 is over, we are setting about working on the summary of our work to chart its new directions. Materials and methods: Standard data reports from the year 2012 have been analysed and compared with data published in the Prenatal Cardiology quarterly in 2011 and other data collected between 2004 and 2010. Results: 538 new records were entered in the Registry in 2012. Consequently, the total number of examinations registered between 2004 and 2012 amounts to 5297 records. 72% (n = 388) of all the patients entered in the Registry were examined by C-type centres, i.e. Warsaw (186), Łódź (150) and Ruda Śląska (79). The commonest heart defects included hypoplastic left heart syndrome (n = 81), tetralogy of Fallot (n = 51) and AVSD (n = 49): atrial & ventricular components (n = 49). The data collected between 2004 and 2010, in 2011 and 2012 were compared. In 2011 544 foetuses with cardiologic problems were registered, while in 2012 there were 538 of them. In 2011, there were 24 centres in the Registry. Last year, there were 27 of them. As in the previous years, HLHS was the most frequently registered foetus heart defect in 2012. In 2012 the second one was TOF. In 2012, LSF and PBU were the two major prenatal cardiology centres in Poland and registered over 100 foetuses every year. In 2012, the number of doctors diagnosing over five cases of foetal heart defects a year reached 10%. The majority of the doctors (89%) diagnosed such cases rarely (< 5 cases a year). In 2011, the percentage of the pregnant women who decided to terminate the pregnancy was larger than between 2004 and 2010, but smaller than in 2012; it was < 7%. Conclusions: The data included in the 2012 in The Polish National Registry for Fetal Cardiac Pathology is similar to the data collected in the previous years. The classification of foetal heart defects is imperfect and interpreted in various ways by particular centres. This needs to be changed in the future; the way the classification is interpreted must be made uniform.","PeriodicalId":415760,"journal":{"name":"Prenatal Cardiology","volume":"180 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115723176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Respondek-Liberska, K. Janiak, M. Słodki, H. Moczulska, J. Moll
Abstract In the Polish National Registry for Fetal Cardiac Pathology d-TGA ranked in 5th place on the list of most common heart defects after HLHS, AVSD, VSD and TOF and accounted for 3,5% of all registered cardiac malformations. The following increase in the detection of d-TGA in Poland was observed: 8 fetuses in 2006, 20 fetuses in 2008, 30 fetuses in 2012 (p<0,05, McNemara test). The aim of this study was to analyze selected fetal and neonatal data in a group of 55 patients with d-TGA in the years 1997-2012 in the single reference prenatal cardiology center, type C (> 120 prenatal CHD per year). Mean gestational age was 28,2+/-4,7 weeks, which decreased from 36st week (in 2007) to 30th week (in 2012) (p=0,006; ANOVA & post hoc NIR test). Demise in utero, termination of pregnancy, demise before cardiac surgery (4%) and postoperative deaths (2%) were taken into account (p >0,05 test χ2). Rashkind procedure during 48h after delivery was performed in 36% of neonates. Conclusion: In the past 12 years we have observed a tendency to better detection of prenatal d-TGA (p <0,05) and to identify d-TGA at earlier gestational age (p=0,006). “Hidden mortality” (before surgery) was higher than postoperative mortality in the neonatal period, however statistically the difference was not significant (p>0,05).
{"title":"Fifty Five Fetuses with D-TGA and their Follow-Up in Single Fetal Cardiac Tertiary Center and Review of the Data from Polish National Registry for Fetal Cardiac Anomalies (WWW.Orkp.Pl)","authors":"M. Respondek-Liberska, K. Janiak, M. Słodki, H. Moczulska, J. Moll","doi":"10.12847/03132","DOIUrl":"https://doi.org/10.12847/03132","url":null,"abstract":"Abstract In the Polish National Registry for Fetal Cardiac Pathology d-TGA ranked in 5th place on the list of most common heart defects after HLHS, AVSD, VSD and TOF and accounted for 3,5% of all registered cardiac malformations. The following increase in the detection of d-TGA in Poland was observed: 8 fetuses in 2006, 20 fetuses in 2008, 30 fetuses in 2012 (p<0,05, McNemara test). The aim of this study was to analyze selected fetal and neonatal data in a group of 55 patients with d-TGA in the years 1997-2012 in the single reference prenatal cardiology center, type C (> 120 prenatal CHD per year). Mean gestational age was 28,2+/-4,7 weeks, which decreased from 36st week (in 2007) to 30th week (in 2012) (p=0,006; ANOVA & post hoc NIR test). Demise in utero, termination of pregnancy, demise before cardiac surgery (4%) and postoperative deaths (2%) were taken into account (p >0,05 test χ2). Rashkind procedure during 48h after delivery was performed in 36% of neonates. Conclusion: In the past 12 years we have observed a tendency to better detection of prenatal d-TGA (p <0,05) and to identify d-TGA at earlier gestational age (p=0,006). “Hidden mortality” (before surgery) was higher than postoperative mortality in the neonatal period, however statistically the difference was not significant (p>0,05).","PeriodicalId":415760,"journal":{"name":"Prenatal Cardiology","volume":"33 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122919597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.5114/PCARD.2020.95250
Oskar Sylwestrzak, M. Respondek-Liberska
Introduction: In December 2019 a novel coronavirus emerged. COVID-19 disease varies in severity. Pregnancy implicates special susceptibility to pathogens and severe pneumonia. It is rational to compare accessible literature and discuss possible prenatal ultrasound monitoring in cases of COVID-19 among gravidas. Material and methods: A PubMed search was conducted, utilising the terms ‘covid 19’ and ‘pregnancy’. Only original source materials were used for comparison. Collected data included: author, date of study, region of study, number of cases, gravidas’ age, trimester of pregnancy during examination, chronic, concomitant diseases, symptoms of infection, type of delivery, Apgar score range, fetal problems, perinatal outcome, and the possibility of vertical transmission. Results: From a total of 39 results initially identified, six matched our search criteria. Mothers’ ages ranged from 22 to 40 years. Mostly they were healthy women, previously with COVID-19 infection, and without chronic diseases. Symptoms of COVID-19 were similar to those presented in the general population: fever, cough, sneezing, nasal congestion, sore throat, myalgia, malaise, dyspnoea, and diarrhoea. Caesarean section constituted 93% of all deliveries. Twenty of 48 (41%) fetuses were delivered preterm. Apgar scores ranged from 7 to 10 points; only one neonate received 7 points. There is no evidence of SARS-CoV-2 vertical transmission until now. Conclusions: Current literature does not allow for more precise description of fetal functional changes in the course of maternal COVID-19. More extensive studies are needed with special consideration of fetal cardiovascular system examination and further postnatal monitoring and more extensive epidemiological evaluation.
{"title":"Prenatal ultrasound evaluation in the current era of COVID-19 – looking only for major congenital defects or subtle sonographic and echocardiographic findings, as well?","authors":"Oskar Sylwestrzak, M. Respondek-Liberska","doi":"10.5114/PCARD.2020.95250","DOIUrl":"https://doi.org/10.5114/PCARD.2020.95250","url":null,"abstract":"Introduction: In December 2019 a novel coronavirus emerged. COVID-19 disease varies in severity. Pregnancy implicates special susceptibility to pathogens and severe pneumonia. It is rational to compare accessible literature and discuss possible prenatal ultrasound monitoring in cases of COVID-19 among gravidas. Material and methods: A PubMed search was conducted, utilising the terms ‘covid 19’ and ‘pregnancy’. Only original source materials were used for comparison. Collected data included: author, date of study, region of study, number of cases, gravidas’ age, trimester of pregnancy during examination, chronic, concomitant diseases, symptoms of infection, type of delivery, Apgar score range, fetal problems, perinatal outcome, and the possibility of vertical transmission. Results: From a total of 39 results initially identified, six matched our search criteria. Mothers’ ages ranged from 22 to 40 years. Mostly they were healthy women, previously with COVID-19 infection, and without chronic diseases. Symptoms of COVID-19 were similar to those presented in the general population: fever, cough, sneezing, nasal congestion, sore throat, myalgia, malaise, dyspnoea, and diarrhoea. Caesarean section constituted 93% of all deliveries. Twenty of 48 (41%) fetuses were delivered preterm. Apgar scores ranged from 7 to 10 points; only one neonate received 7 points. There is no evidence of SARS-CoV-2 vertical transmission until now. Conclusions: Current literature does not allow for more precise description of fetal functional changes in the course of maternal COVID-19. More extensive studies are needed with special consideration of fetal cardiovascular system examination and further postnatal monitoring and more extensive epidemiological evaluation.","PeriodicalId":415760,"journal":{"name":"Prenatal Cardiology","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123114942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.5114/pcard.2022.124101
M. Pietrolucci, P. Maqina, Sara Greco, G. Berti, Virginia Viviano, G. Rizzo
{"title":"Evaluation of an artificial intelligence algorithm (HeartAssistᵀᴹ) in the assessment of fetal cardiothoracic ratio: a prospective study","authors":"M. Pietrolucci, P. Maqina, Sara Greco, G. Berti, Virginia Viviano, G. Rizzo","doi":"10.5114/pcard.2022.124101","DOIUrl":"https://doi.org/10.5114/pcard.2022.124101","url":null,"abstract":"","PeriodicalId":415760,"journal":{"name":"Prenatal Cardiology","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125547080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hypoplastic Left Heart Syndrome (HLHS) is the most common heart defect in the population of fetuses and majority of Polish women deceided to continue their pregnancies despite prenatal diagnosis. The aim of the study: Are there any differences in newborns with HLHS after prenatal diagnoses and with postnatal diagnoses, operated on in ICZMP (Polish Mother’s Memorial Hospital) in Lodz in the years 2005-2010. Material and Methods: A retrospective analysis of medical records of 155 newborns from the subdivision of Anaesthesiology and Paediatric Intensive Care (ICZMP) in two groups: prenatally diagnosed (n = 87) and without prenatal diagnosis (n = 68). Results: Newborns were born with normal birth weights, in two groups prenatal and postnatal (3109.5 ± 494.8g vs. 3258.6 ± 443.1 g, p = 0.06 ). Most of them (85%) were born on time and in good condition (9-10 points on the Apgar). The surgery was performed earlier in prenatal group (p = 0.0364). The chance of surgery between 6th and 10th day after birth in prenatal group was twice as high as in the group diagnosed after birth (OR = 2.0 [0.9 4.3]). The infant’s average length of stay in the ICU after the first stage of treatment was 8 days and was almost the same in both groups (8,0 [5,0 20,5] vs. 8,0 16,0]; NS). Total mortality was 19.4% and it did not differ in both groups (p = 0.4596). The risk of death in prematurity group was 5x higher than in group of newborns delivered at term (p=0,0073). In prenatal group cardiac surgery was earlier than in group diagnosed after delivery (p=0,0364). Neonates with late surgery had longer hospitalization, compared with early surgery (44 days vs 33 days, p=0,0073). Longer hospital stay means higher hospital cost (for cardiac surgery department circa 3000 zł per 1 patient with HLHS, meaning 90 000 zl per year for 30 patients). Conclusions: 1) The neonatal outcome of newborns with HLHS in ICU, in our center in years 2005-2010, in two groups: after prenatal diagnoses and in postnatal diagnoses, were similar. 2) The main differences were a) an increased risk of death in case of premature delivery (p=0,0073) b) earlier I stage Norwood in prenatal group (p=0,0364) meaning lower costs for single institution, meaning lower costs for the National Health System.
{"title":"Lower costs of hospital stay for newborns with HLHS after prenatal diagnoses comparing with postnatal diagnoses","authors":"Monika Wojtyra, J. Moll, M. Respondek-Liberska","doi":"10.12847/06132","DOIUrl":"https://doi.org/10.12847/06132","url":null,"abstract":"Hypoplastic Left Heart Syndrome (HLHS) is the most common heart defect in the population of fetuses and majority of Polish women deceided to continue their pregnancies despite prenatal diagnosis. The aim of the study: Are there any differences in newborns with HLHS after prenatal diagnoses and with postnatal diagnoses, operated on in ICZMP (Polish Mother’s Memorial Hospital) in Lodz in the years 2005-2010. Material and Methods: A retrospective analysis of medical records of 155 newborns from the subdivision of Anaesthesiology and Paediatric Intensive Care (ICZMP) in two groups: prenatally diagnosed (n = 87) and without prenatal diagnosis (n = 68). Results: Newborns were born with normal birth weights, in two groups prenatal and postnatal (3109.5 ± 494.8g vs. 3258.6 ± 443.1 g, p = 0.06 ). Most of them (85%) were born on time and in good condition (9-10 points on the Apgar). The surgery was performed earlier in prenatal group (p = 0.0364). The chance of surgery between 6th and 10th day after birth in prenatal group was twice as high as in the group diagnosed after birth (OR = 2.0 [0.9 4.3]). The infant’s average length of stay in the ICU after the first stage of treatment was 8 days and was almost the same in both groups (8,0 [5,0 20,5] vs. 8,0 16,0]; NS). Total mortality was 19.4% and it did not differ in both groups (p = 0.4596). The risk of death in prematurity group was 5x higher than in group of newborns delivered at term (p=0,0073). In prenatal group cardiac surgery was earlier than in group diagnosed after delivery (p=0,0364). Neonates with late surgery had longer hospitalization, compared with early surgery (44 days vs 33 days, p=0,0073). Longer hospital stay means higher hospital cost (for cardiac surgery department circa 3000 zł per 1 patient with HLHS, meaning 90 000 zl per year for 30 patients). Conclusions: 1) The neonatal outcome of newborns with HLHS in ICU, in our center in years 2005-2010, in two groups: after prenatal diagnoses and in postnatal diagnoses, were similar. 2) The main differences were a) an increased risk of death in case of premature delivery (p=0,0073) b) earlier I stage Norwood in prenatal group (p=0,0364) meaning lower costs for single institution, meaning lower costs for the National Health System.","PeriodicalId":415760,"journal":{"name":"Prenatal Cardiology","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125561233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.5114/pcard.2021.109175
Halis Özdemir, Kemal Hansu, P. Calis, D. Karçaaltıncaba, M. Bayram
Introduction: The objective of this study was to test the hypothesis that antenatal corticosteroid therapy alters fetal cardiopulmonary and uteroplacental blood flow in pregnancies. Material and methods: Twenty-seven singleton pregnancies between 28 and 34 gestational weeks classified as at risk of preterm birth were included prospectively. We evaluated fetal main pulmonary artery (MPA), left and right pulmonary artery (PA), left myocardial performance index (Tei index), tricuspid valve (TV), umbilical artery (UmA), middle cerebral artery (MCA), and ductus venosus (DV) parameters before and 48 hours and 7 days after antenatal steroid administration. Results: The mean age was 31 years, and the mean gestational age was 31 weeks. The UmA S/D (Systole/Diastole) ratio, PI (pulsatility index) and RI (resistive index) values, and Doppler parameters of other vessels were not different when comparing between before and after steroid administration. Except for MCA PSV (peak systolic velocity) values, the other MCA Doppler parameters (S/D, PI, RI) were all significantly decreased. The cerebroplacental ratio (CPR) and CPR percentile values decreased significantly. All tested cardiac parameters were unchanged, except MPA ejection time (ET) ( p = 0.016). Conclusions: Our data demonstrate altered fetal MCA and CPR with corticosteroid therapy. These data suggest that antenatal corticosteroid therapy has no impact on any Doppler parameters of fetal cardiopulmonary and uteroplacental blood flow in pregnancies.
{"title":"Does betamethasone therapy impact fetal multivessel Doppler parameters?","authors":"Halis Özdemir, Kemal Hansu, P. Calis, D. Karçaaltıncaba, M. Bayram","doi":"10.5114/pcard.2021.109175","DOIUrl":"https://doi.org/10.5114/pcard.2021.109175","url":null,"abstract":"Introduction: The objective of this study was to test the hypothesis that antenatal corticosteroid therapy alters fetal cardiopulmonary and uteroplacental blood flow in pregnancies. Material and methods: Twenty-seven singleton pregnancies between 28 and 34 gestational weeks classified as at risk of preterm birth were included prospectively. We evaluated fetal main pulmonary artery (MPA), left and right pulmonary artery (PA), left myocardial performance index (Tei index), tricuspid valve (TV), umbilical artery (UmA), middle cerebral artery (MCA), and ductus venosus (DV) parameters before and 48 hours and 7 days after antenatal steroid administration. Results: The mean age was 31 years, and the mean gestational age was 31 weeks. The UmA S/D (Systole/Diastole) ratio, PI (pulsatility index) and RI (resistive index) values, and Doppler parameters of other vessels were not different when comparing between before and after steroid administration. Except for MCA PSV (peak systolic velocity) values, the other MCA Doppler parameters (S/D, PI, RI) were all significantly decreased. The cerebroplacental ratio (CPR) and CPR percentile values decreased significantly. All tested cardiac parameters were unchanged, except MPA ejection time (ET) ( p = 0.016). Conclusions: Our data demonstrate altered fetal MCA and CPR with corticosteroid therapy. These data suggest that antenatal corticosteroid therapy has no impact on any Doppler parameters of fetal cardiopulmonary and uteroplacental blood flow in pregnancies.","PeriodicalId":415760,"journal":{"name":"Prenatal Cardiology","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115031610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.5114/PCARD.2019.90997
Justin Kochanski, D. Bardo, L. Goncalves, C. Lindblade
Scimitar syndrome is a rare condition characterised by abnormal pulmonary venous return to the inferior vena cava. It is associated with various cardiopulmonary malformations such as atrial-septal defects, aorticopulmonary collateral vessels, and pulmonary hypoplasia. Diagnosis is typically within the first few months of life. We report a unique case of scimitar syndrome that was diagnosed prenatally using multiple imaging modalities. In addition to two right-sided scimitar veins draining into the suprahepatic inferior vena cava, this patient was found to have horseshoe lung morphology with right pulmonary hypoplasia, a perimembranous ventricular septal defect, sequestered lung tissue, and an aorticopulmonary collateral vessel arising from the descending aorta. The prenatal diagnosis allowed for timely medical and surgical intervention in the postnatal period, which is detailed in this report.
{"title":"Prenatal diagnosis of a unique scimitar syndrome variant – a case report","authors":"Justin Kochanski, D. Bardo, L. Goncalves, C. Lindblade","doi":"10.5114/PCARD.2019.90997","DOIUrl":"https://doi.org/10.5114/PCARD.2019.90997","url":null,"abstract":"Scimitar syndrome is a rare condition characterised by abnormal pulmonary venous return to the inferior vena cava. It is associated with various cardiopulmonary malformations such as atrial-septal defects, aorticopulmonary collateral vessels, and pulmonary hypoplasia. Diagnosis is typically within the first few months of life. We report a unique case of scimitar syndrome that was diagnosed prenatally using multiple imaging modalities. In addition to two right-sided scimitar veins draining into the suprahepatic inferior vena cava, this patient was found to have horseshoe lung morphology with right pulmonary hypoplasia, a perimembranous ventricular septal defect, sequestered lung tissue, and an aorticopulmonary collateral vessel arising from the descending aorta. The prenatal diagnosis allowed for timely medical and surgical intervention in the postnatal period, which is detailed in this report.","PeriodicalId":415760,"journal":{"name":"Prenatal Cardiology","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114872659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K. Piątek, K. Zych-Krekora, J. Płużańska, E. Gulczyńska, M. Respondek-Liberska
Abstract Complains about prenatal diagnoses usually touch late diagnosis, missed diagnosis or uncomplete diagnosis. Prenatal diagnose provides usually important information for parents, obstetrician and neonatologist. Successful perinatal care is based on a good cooperation of the perinatal team. This time we present a peculiar situation when improper reading of prenatal diagnosis had caused a lot of troubles for the patient, parents and hospital staff.
{"title":"How \"fast\" reading of prenatal cardiac diagnosis may badly influence the neonatal management - case report from tertiary center in 2015 and literature review","authors":"K. Piątek, K. Zych-Krekora, J. Płużańska, E. Gulczyńska, M. Respondek-Liberska","doi":"10.12847/09158","DOIUrl":"https://doi.org/10.12847/09158","url":null,"abstract":"Abstract Complains about prenatal diagnoses usually touch late diagnosis, missed diagnosis or uncomplete diagnosis. Prenatal diagnose provides usually important information for parents, obstetrician and neonatologist. Successful perinatal care is based on a good cooperation of the perinatal team. This time we present a peculiar situation when improper reading of prenatal diagnosis had caused a lot of troubles for the patient, parents and hospital staff.","PeriodicalId":415760,"journal":{"name":"Prenatal Cardiology","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134008883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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