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Mitteilungen des Berufsverbands der Pneumologen in Baden- Württemberg 别耍横
Q4 Medicine
PNEUMOLOGE
Pub Date : 2021-01-26 DOI: 10.1007/s10405-020-00377-8
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引用次数: 0
Pulmonalarterieller Hochdruck bei Kindern 儿童肺动脉高压
Q4 Medicine
PNEUMOLOGE
Pub Date : 2021-01-20 DOI: 10.1007/s10405-020-00371-0
M. Gorenflo, V. Ziesenitz
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引用次数: 0
Transition von Patienten mit primärer ziliärer Dyskinesie 原发性睫状体运动障碍患者的过渡期
Q4 Medicine
PNEUMOLOGE
Pub Date : 2021-01-14 DOI: 10.1007/s10405-020-00369-8
C. Schmalstieg, H. Omran
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引用次数: 0
Rezidivierende „Infekte“ bei einer Landwirtin 农民反复感染
Q4 Medicine
PNEUMOLOGE
Pub Date : 2021-01-08 DOI: 10.1007/s10405-020-00375-w
C. Stolpe
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引用次数: 0
Mukoviszidose und Transition ins Erwachsenenalter 变异性纤维化及成人化
Q4 Medicine
PNEUMOLOGE
Pub Date : 2021-01-05 DOI: 10.1007/s10405-020-00367-w
F. Stehling, S. Sutharsan, S. Straßburg, C. Taube, M. Olivier, M. Steindor, M. Welsner
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引用次数: 0
Probleme der Inhalation im Alter 吸入年龄有问题
Q4 Medicine
PNEUMOLOGE
Pub Date : 2021-01-05 DOI: 10.1007/s10405-020-00370-1
P. Haidl, K. Siemon, J. Mezrhab
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引用次数: 1
Transition bei chronisch obstruktiven Lungenerkrankungen von pädiatrischer in internistische lungenärztliche Versorgung 儿科儿科肺气肿移转性肺炎病例
Q4 Medicine
PNEUMOLOGE
Pub Date : 2021-01-05 DOI: 10.1007/s10405-020-00368-9
M. Gappa, M. Lommatzsch
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引用次数: 1
Spirometrie im höheren Lebensalter 老年人肺活量测定
Q4 Medicine
PNEUMOLOGE
Pub Date : 2021-01-04 DOI: 10.1007/s10405-020-00365-y
J. Schlitzer, S. Stieglitz, H. Frohnhofen
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引用次数: 0
[Aging of the lungs and immune system as hellmark in the pathogenesis of idiopathic pulmonary fibrosis and COVID-19]. [肺和免疫系统老化在特发性肺纤维化和COVID-19发病机制中的标志]。
Q4 Medicine
PNEUMOLOGE
Pub Date : 2021-01-01 Epub Date: 2021-01-24 DOI: 10.1007/s10405-020-00374-x
Sven Stieglitz, Helmut Frohnhofen

Idiopathic pulmonary fibrosis (IPF) does not occur in younger persons. Therefore, it is not surprising that the nine hallmarks of biological aging can all be found in the pathomechanism of IPF. In this respect the homeostasis of cellular protein synthesis, degradation and recycling becomes unbalanced, which causes a dysregulation of repair mechanisms in the case of lung damage. Severve acute respiratory syndrome coronarvius type 2 (SARS-CoV-2) infections may also predominantyl seen in aged persons. In this situation cellular aging of the lungs also plays a role but additionally, the aging of the immune system is also of great importance. Immunosenescence is associated with a loss of naïve T‑cells. Moreover, there are gender-specific differences with a loss of B‑cells only in men but not in women, which partly explains the more severe course of COVID-19 pneumonia in older men.

特发性肺纤维化(IPF)不发生在年轻人。因此，在IPF的病理机制中发现生物衰老的九个标志也就不足为奇了。在这方面，细胞蛋白质合成、降解和再循环的稳态变得不平衡，从而导致肺损伤的修复机制失调。严重急性呼吸综合征冠状病毒2型(SARS-CoV-2)感染也可能主要见于老年人。在这种情况下，肺细胞老化也起作用，但除此之外，免疫系统的老化也很重要。免疫衰老与naïve T细胞的丢失有关。此外，存在性别差异，只有男性而女性没有B细胞损失，这在一定程度上解释了老年男性COVID-19肺炎病程更严重的原因。
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引用次数: 0
[Prevention by vaccination of adult patients with pulmonary diseases]. [成年肺病患者的疫苗接种预防]。
Q4 Medicine
PNEUMOLOGE
Pub Date : 2021-01-01 Epub Date: 2021-07-12 DOI: 10.1007/s10405-021-00402-4
Carolin Dodt, Mathias W Pletz, Martin Kolditz

The key priority in patients with chronic lung diseases is currently immunization against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); all vaccines approved for this showed high effectiveness against severe infections. For patients with chronic pulmonary diseases the recommendations by the Standing Committee on Vaccination include not only the standard vaccinations in adulthood but also the so-called indication vaccinations. These include vaccinations against pneumococci and influenza. Advances include the recent development of new pneumococcal conjugate vaccines containing additional serotypes and the recommendation of a more effective high-dose vaccine against influenza for persons over 60 years old. With the next scheduled booster vaccination against tetanus and diphtheria a combination vaccine with pertussis antigen should be used. For patients with chronic lung disease the herpes zoster vaccine is recommended over the age of 50 years.

目前，慢性肺部疾病患者的首要任务是接种严重急性呼吸系统综合症冠状病毒 2（SARS-CoV-2）疫苗；已获批准的所有疫苗都显示出对严重感染的高度有效性。对于慢性肺病患者，疫苗接种常设委员会的建议不仅包括成年期的标准疫苗接种，还包括所谓的适应症疫苗接种。其中包括肺炎球菌和流感疫苗。疫苗接种方面的进展包括最近开发出的含有更多血清型的新型肺炎球菌结合疫苗，以及针对 60 岁以上人群推荐的更有效的高剂量流感疫苗。在下一次接种破伤风和白喉强化疫苗时，应使用含百日咳抗原的联合疫苗。建议 50 岁以上的慢性肺病患者接种带状疱疹疫苗。
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引用次数: 0
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