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Evidence-based decision-making 以证据为基础的决策
IF 0.1 Q4 Medicine Pub Date : 2022-01-01 DOI: 10.4103/jhnps.jhnps_5_22
Vino V. Kurien, S. Shamsuddeen, M. Mahitha, Diya S Rasheed
Evidence-based decision-making (EBDM) entails the explicit, conscientious, and prudent evaluation of the best available information in making medical decisions. The process of EBDM involves learning the latest approaches and gaining new skills such as how to ask excellent clinical questions, carrying out a computerized search, critically evaluating the evidence, utilizing the findings in clinical settings, and analyzing the process. This method acknowledges that it is difficult for the practitioners to be totally up to date on all illnesses, treatments, materials, or products accessible. As a result, EBDM provides a method for filling in these knowledge gaps to give the best possible care. The basic goal of evidence-based practice is to improve health-care quality. It assists to arrive at a clinical decision on the basis of the latest and advanced research and the best possible evidence. Facilitating EBDM that leads to better patient outcomes, smarter research planning, better products, and improved policy formulation is critical and timely. This article gives an insight into EBDM and various levels of evidence.
循证决策(EBDM)要求在做出医疗决策时对最佳可用信息进行明确、认真和谨慎的评估。EBDM的过程包括学习最新的方法和获得新的技能,如如何提出优秀的临床问题,进行计算机搜索,批判性地评估证据,在临床环境中利用发现,以及分析过程。这种方法承认,从业者很难完全了解所有疾病、治疗方法、材料或产品的最新情况。因此,EBDM提供了一种填补这些知识空白的方法,以提供尽可能好的护理。循证实践的基本目标是提高医疗保健质量。它有助于在最新和先进的研究以及尽可能好的证据的基础上做出临床决策。促进EBDM以获得更好的患者结果、更智能的研究规划、更好的产品和改进的政策制定至关重要且及时。这篇文章深入了解了EBDM和各种级别的证据。
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引用次数: 0
Sonoelastography in differentiation between metastatic and tuberculous lymphadenitis 超声弹性图鉴别转移性和结核性淋巴结炎
IF 0.1 Q4 Medicine Pub Date : 2022-01-01 DOI: 10.4103/jhnps.jhnps_81_21
R. Yadav, A. Malik, Rajni Prasad
Introduction: The purpose of this study was to evaluate the diagnostic accuracy of sonography including Doppler and sonoelastography in differentiation between metastatic and tuberculous cervical lymphadenopathy. Materials and Methods: This single-center observational study was undertaken with 86 study subjects after defined inclusion and exclusion criteria as per study needs and imaging limitations. Sonographic and sonoelastographic examinations were done by two examiners, and the diagnosis was reached in consensus. Sonographic features assessed were size, short/long axis ratio, the presence or absence of echogenic hilum, and intranodal necrosis including pattern of vascularity. With ultrasonoelastography, color-coded elastograms and strain ratio (SR) were evaluated. Then, the accuracy of individual sonographic and sonoelastographic parameters as well as combined sonographic and sonoelastographic evaluation was evaluated against HPE diagnosis. Cutoff for all the combined evaluations was determined from receiver observing curve. Results: Out of 127 nodes examined, 100 were tuberculous and 27 were metastatic on histopathology. Among all ultrasound features, intranodal necrosis showed maximum sensitivity, i.e., 39% and specificity 96%. SR had highest sensitivity (95.6%) and specificity (96.3%) among all US and elastographic parameters. Conclusion: Sonoelastographic assessment has good diagnostic accuracy for differentiation between metastatic and tuberculous cervical lymphadenopathy and adds to sonographic assessment, thereby further increasing the diagnostic confidence.
引言:本研究的目的是评估超声(包括多普勒和声弹性成像)在鉴别转移性和结核性颈淋巴结病中的诊断准确性。材料和方法:这项单中心观察性研究对86名受试者进行,根据研究需求和成像限制,确定了纳入和排除标准。两名检查人员分别进行了声像图和声弹性图检查,诊断结果一致。评估的声像图特征包括大小、长短轴比、有无回声门和包括血管模式在内的结节内坏死。利用超声弹性成像,对彩色编码弹性图和应变率(SR)进行评估。然后,根据HPE诊断,评估单个超声和声弹性成像参数以及超声和声弹成像联合评估的准确性。所有组合评估的截止值由受试者观察曲线确定。结果:127个淋巴结中,100个为结核性淋巴结,27个为转移性淋巴结。在所有超声特征中,结节内坏死显示出最大的敏感性,即39%和特异性96%。SR在所有US和弹性成像参数中具有最高的敏感性(95.6%)和特异性(96.3%)。结论:超声弹性成像评估对鉴别转移性和结核性颈部淋巴结病具有良好的诊断准确性,并增加了超声评估,从而进一步提高了诊断的可信度。
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引用次数: 0
Reliability and reproducibility of measurements in cephalometric radiography acquired by a charge-coupled device imaging system 电荷耦合装置成像系统获取的头影测量射线照相测量的可靠性和再现性
IF 0.1 Q4 Medicine Pub Date : 2022-01-01 DOI: 10.4103/jhnps.jhnps_15_22
A. Abdelrahim, A. Abuaffan
Objective: To evaluate and compare the reliability, reproducibility, and speed of two cephalometric tracing methods computer-aided cephalometric tracing and manual tracing. Materials and Methods: This was an analytical, cross-sectional study. One hundred and three pretreatment cephalometric radiographs were randomly selected from the orthodontics department of a public university. Twelve cephalometric landmarks were identified, and fifteen measurements were calculated both manually and digitally using Vistadent OC software. The reliability of measurements was assessed for each method by applying the intraclass correlation coefficient (ICC). Paired t-test was used to compare the measurements' reproducibility and time difference between the two methods. Results: All angular and linear measurements for both the methods showed a range of moderate correlation (0.8 ≥ ICC ≥0.5) to strong correlation (ICC ≥0.8) except for L1-MAD, which displayed a poor correlation for both manual and digital tracing, (ICC = 0.36 and 0.33, respectively), as well as digital tracing of interincisal angle (ICC = 0.36). No statistically significant differences between the two methods were observed for all angular and linear measurements except upper anterior facial height (UAFH) and lower anterior facial height (P = 0.000). There was a statistically significant time difference between the two techniques (P = 0.000). The mean tracing time of the operator for single tracing was 18.02 min for manual tracing and 8.85 min when using the Vistadent program. Conclusion: Cephalometric measurements in conventional manual and digital cephalometric analysis are highly reliable. Although the reproducibility of some measurements between two methods showed statistically significant differences, most differences were considered minimal and clinically acceptable. Computer-assisted cephalometric analysis proved to be more time-efficient.
目的:评价和比较计算机辅助头像追踪和人工头像追踪两种头像追踪方法的可靠性、再现性和速度。材料和方法:这是一项分析性横断面研究。从某公立大学正畸科随机抽取预处理头颅x线片103张。确定了12个头颅测量标志,并使用Vistadent OC软件手动和数字计算了15个测量值。采用类内相关系数(intraclass correlation coefficient, ICC)评价各方法测量结果的可靠性。采用配对t检验比较两种方法测量结果的重复性和时间差。结果:两种方法的所有角度和线性测量结果均显示中等相关性(0.8≥ICC≥0.5)至强相关性(ICC≥0.8),除了L1-MAD,其与手工和数字示图的相关性较差(ICC分别为0.36和0.33),以及数字示图的内切角(ICC = 0.36)。两种方法之间除了上前面部高度(UAFH)和下前面部高度外,所有角度和线性测量均无统计学差异(P = 0.000)。两种方法的时间差异有统计学意义(P = 0.000)。单次人工追踪平均追踪时间为18.02 min,使用Vistadent程序时平均追踪时间为8.85 min。结论:头颅测量在传统手工和数字头颅测量分析中具有较高的可靠性。虽然两种方法之间的一些测量结果的可重复性显示出统计学上的显著差异,但大多数差异被认为是最小的,临床上是可以接受的。计算机辅助的头颅测量分析被证明更省时。
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引用次数: 0
Prevalence of thyroid lesions in thyroidectomy specimens - A histomorphological study in urban industrial area 甲状腺切除术标本中甲状腺病变的患病率-城市工业区的组织形态学研究
IF 0.1 Q4 Medicine Pub Date : 2022-01-01 DOI: 10.4103/jhnps.jhnps_71_21
S. Chandanwale, Diva Sutreja, P. Patel, A. Verma, S. Kulkarni
Introduction: The prevalence of thyroid diseases is enormous in general population of India and more common in women than men. Although the World Health Organization assessment status has classified India as having optimal iodine nutrition in 2004, hypothyroidism still contributes significantly to burden of thyroid disorders in India. The prevalence of thyroid diseases varies according to different geographical areas, age, and sex. The aim of this study is to determine the pattern of thyroid lesions in surgically resected specimens in urban industrial area and to study their histomorphological features. Materials and Methods: The 430 patients in whom partial or complete surgical resection of thyroid was done were included in the study. The histomorphological features were studied in detail and correlated with clinical findings. Results: The majority of thyroid specimens (90.71%) were total thyroidectomies. More than half, i.e., 54.65% (n = 235) of the thyroidectomies were done in 3rd and 4th decade. The 85.11% (n = 366) were female patients. The multinodular goiter was the commonest etiology (n = 341) for thyroidectomy. The follicular adenoma (n = 25) and the papillary thyroid carcinoma (n = 20) were common neoplastic lesion. Conclusion: The thyroid lesions in females more often require surgical intervention as compared to males. The 31–50 years is the most common age group who require surgical intervention. The substantial number of younger females in the age group of 16–30 years requires surgical intervention. The multinodular goiter due to iodine deficiency appears to be most common cause of thyroidectomy. The early diagnosis and proper therapy is the key for reducing the thyroidectomies in younger females.
引言:甲状腺疾病在印度普通人群中的患病率很高,女性比男性更常见。尽管世界卫生组织的评估状况将印度列为2004年碘营养最佳的国家,但甲状腺功能减退症仍然是印度甲状腺疾病负担的主要原因。甲状腺疾病的患病率因地理区域、年龄和性别的不同而不同。本研究的目的是确定城市工业区手术切除标本中甲状腺病变的模式,并研究其组织形态学特征。材料和方法:430例甲状腺部分或全部手术切除的患者纳入研究。对其组织形态学特征进行了详细研究,并与临床表现相关联。结果:甲状腺标本以甲状腺全切除术为主,占90.71%。超过一半,即54.65%(n=235)的甲状腺切除术是在第3和第4个十年内完成的。女性患者占85.11%(n=366)。多结节性甲状腺肿是甲状腺切除术最常见的病因(n=341)。滤泡性腺瘤(n=25)和甲状腺乳头状癌(n=20)是常见的肿瘤病变。结论:与男性相比,女性甲状腺病变更需要手术干预。31-50岁是需要手术干预的最常见年龄组。16-30岁年龄段的大量年轻女性需要手术干预。碘缺乏引起的多结节性甲状腺肿似乎是甲状腺切除术最常见的原因。早期诊断和正确治疗是减少年轻女性甲状腺切除术的关键。
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引用次数: 0
Cytological accuracy of nonguided fine needle aspiration from the thyroid - A two-year experience from southern India 非引导甲状腺细针穿刺的细胞学准确性-印度南部两年的经验
IF 0.1 Q4 Medicine Pub Date : 2022-01-01 DOI: 10.4103/jhnps.jhnps_77_21
Ranganath Ratnagiri, Shubranshu Jena, Monalisa Hui, S. Uppin, Rajashekar Shantappa
Introduction: 12.2% of the Indian have a palpable thyroid nodule, but only 5% of these are malignant. The rest of the patients do not need to undergo surgery, unless clinically indicated for other reasons. Fine needle aspiration cytology (FNA) from the thyroid gland is the most commonly performed screening investigation to determine whether a patient needs surgery or not. The sensitivity, specificity and accuracy of FNA should therefore, be audited in every Institute from their own data. Materials and Methods: A retrospective analysis of the case records of all patients of thyroid nodules who underwent surgery at our hospital between September 2019 and September 2021 was undertaken. Clinical, demographic details as well as correlation between the nonguided FNA report and the final histopathology was done. The sensitivity, specificity, positive and negative predictive value as well as accuracy of FNA was calculated. Results: The sensitivity of FNA for malignancy was 73.1% and the specificity was 89.3%. The positive predictive value was 85.7% and the negative predictive value was 79.2%. The accuracy of nonguided FNA was 81.8%. Conclusions: Though there were no inadequate smears, the high false negative rate and the lower accuracy point toward the need to use ultra-sonography guidance in selected cases to overcome the pitfalls of nonguided FNAs.
引言:12.2%的印度人有可触及的甲状腺结节,但其中只有5%是恶性的。其余患者不需要接受手术,除非临床上有其他原因。甲状腺细针抽吸细胞学(FNA)是最常见的筛查研究,以确定患者是否需要手术。因此,每个研究所都应该根据自己的数据对FNA的敏感性、特异性和准确性进行审计。材料和方法:对2019年9月至2021年9月在我院接受手术的所有甲状腺结节患者的病例记录进行回顾性分析。对临床、人口统计学细节以及非引导性FNA报告与最终组织病理学之间的相关性进行了研究。计算FNA的敏感性、特异性、阳性和阴性预测值以及准确性。结果:FNA对恶性肿瘤的敏感性为73.1%,特异性为89.3%,阳性预测值为85.7%,阴性预测值为79.2%,非引导FNA的准确率为81.8%,高的假阴性率和较低的准确性表明需要在选定的病例中使用超声引导来克服非引导FNA的缺陷。
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引用次数: 0
Carotid body tumor: Surgical management and complications 颈动脉体瘤的外科治疗及并发症
IF 0.1 Q4 Medicine Pub Date : 2021-07-01 DOI: 10.4103/jhnps.jhnps_62_21
Ishwar Singh, R. Meher, P. Bhandari, Karandeep Singh
Introduction: Carotid body tumors (CBT) or paragangliomas account for approximately 3% of all paragangliomas occurring in the head-and-neck region. Delay in the surgical resection of tumors may be associated with high morbidity or mortality and risk of malignant transformation. Methodology: Three cases of CBTs were included in the study, out of which one case presented as bilateral neck swelling. All the patients were clinically and radiologically evaluated and taken up for surgical excision of the tumor. In case with bilateral tumor, a staged removal was planned. Results: Out of three patients, a female patient developed stroke postoperatively, she was managed and discharged in stable condition, and another male patient developed left vagal palsy. Conclusion: Excision of shambling Type III CBTs is difficult and one should know the collateral circulation of the tumor preoperatively. Bilateral CBT resection requires staging procedures to reduce the risk of cardiovascular and neurological issues.
引言:颈动脉体肿瘤(CBT)或副神经节瘤约占头颈部所有副神经节瘤的3%。肿瘤手术切除的延迟可能与高发病率或死亡率以及恶性转化的风险有关。方法:本研究包括三例CBT,其中一例表现为双侧颈部肿胀。所有患者均接受了临床和放射学评估,并接受了肿瘤手术切除。对于双侧肿瘤,计划分期切除。结果:在三名患者中,一名女性患者术后出现中风,病情稳定并出院,另一名男性患者出现左迷走神经麻痹。结论:III型CBTs手术切除困难,术前应了解肿瘤的侧支循环情况。双侧CBT切除需要分期手术,以降低心血管和神经系统问题的风险。
{"title":"Carotid body tumor: Surgical management and complications","authors":"Ishwar Singh, R. Meher, P. Bhandari, Karandeep Singh","doi":"10.4103/jhnps.jhnps_62_21","DOIUrl":"https://doi.org/10.4103/jhnps.jhnps_62_21","url":null,"abstract":"Introduction: Carotid body tumors (CBT) or paragangliomas account for approximately 3% of all paragangliomas occurring in the head-and-neck region. Delay in the surgical resection of tumors may be associated with high morbidity or mortality and risk of malignant transformation. Methodology: Three cases of CBTs were included in the study, out of which one case presented as bilateral neck swelling. All the patients were clinically and radiologically evaluated and taken up for surgical excision of the tumor. In case with bilateral tumor, a staged removal was planned. Results: Out of three patients, a female patient developed stroke postoperatively, she was managed and discharged in stable condition, and another male patient developed left vagal palsy. Conclusion: Excision of shambling Type III CBTs is difficult and one should know the collateral circulation of the tumor preoperatively. Bilateral CBT resection requires staging procedures to reduce the risk of cardiovascular and neurological issues.","PeriodicalId":41774,"journal":{"name":"Journal of Head & Neck Physicians and Surgeons","volume":null,"pages":null},"PeriodicalIF":0.1,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44759022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Malignant proliferating trichilemmal tumor in neck: A rare clinical presentation and review of 50 cases from literature 颈部恶性增殖性毛球瘤:一例罕见的临床表现及50例文献复习
IF 0.1 Q4 Medicine Pub Date : 2021-07-01 DOI: 10.4103/jhnps.jhnps_44_21
K. Prasad, A. Harish
Background: Proliferating trichilemmal tumor is a rare cutaneous neoplasm derived from the outer root sheath of the hair follicle which usually presents as a solitary lesion, in fourth to eighth decades of life, and has a predilection for women. The scalp is the most common site of occurrence of this tumor. Malignant proliferating trichilemmal tumor (MPTT) invades surrounding tissues or metastasizes with features of cellular pleomorphism and nuclear atypia. Local recurrences have been occurred in about 3.7%–6.6%. Complete surgical excision with a margin of normal tissue is the standard treatment. Aim: To present a rare case of MPTT over the upper part of the neck which presented to our ENT department and to review about 50 cases of this entity in terms of age, sex, location, treatment, and outcome. Methods: The detailed description of the case of MPTT presented over the upper part of the neck to our ENT department will be given. Literature was reviewed for similar cases of this entity and was studied in terms of age, sex, location of tumor, treatment, and outcome. Results: Out of the 50 cases reviewed, majority of the patients were females, between the age group 40 and 80 years. The scalp was the common site of tumor. All the cases were treated surgically. Conclusion: MPTT is a rare neoplasm which carries a diagnostic dilemma and is often confused with squamous cell carcinoma. Wide excision of MPTT with an adequate clearance margin is the treatment of choice.
背景:增殖性毛突肿瘤是一种罕见的皮肤肿瘤,起源于毛囊外根鞘,通常表现为孤立病变,发生在40至80岁之间,多发于女性。头皮是这种肿瘤最常见的发生部位。恶性增生性滴管肿瘤(MPTT)侵袭周围组织或转移,具有细胞多形性和核异型性的特点。局部复发率约3.7% ~ 6.6%。标准的治疗方法是完全切除正常组织的边缘。目的:报告一例罕见的颈上部MPTT病例,并对50例此类病例的年龄、性别、部位、治疗和预后进行回顾性分析。方法:对颈上部MPTT病例进行详细描述。我们回顾了类似病例的文献,并根据年龄、性别、肿瘤位置、治疗和结果进行了研究。结果:本组50例患者以女性居多,年龄在40 ~ 80岁之间。头皮是肿瘤的常见部位。所有病例均行手术治疗。结论:MPTT是一种罕见的肿瘤,诊断困难,常与鳞状细胞癌混淆。广泛切除MPTT并有足够的间隙是治疗的选择。
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引用次数: 0
Head and neck oncology practise in the post-COVID era 后covid时代头颈部肿瘤学实践
IF 0.1 Q4 Medicine Pub Date : 2021-07-01 DOI: 10.4103/jhnps.jhnps_67_21
P. Pai
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引用次数: 0
Sutureless technique for thyroidectomy: Systematic review of literature 无缝线技术用于甲状腺切除术:文献系统回顾
IF 0.1 Q4 Medicine Pub Date : 2021-07-01 DOI: 10.4103/jhnps.jhnps_42_21
Nitin Khunteta, J. Badwal
The purpose of the present systematic review is to compare the outcomes and complications of two techniques of thyroidectomy: the surgical technique for thyroidectomy performed by a sealing device (LigaSure small jaw) versus conventional clamp-and-tie technique (CAT). Clinical studies were retrieved from the electronic databases of PubMed, EMBASE, and Scopus. One-hundred and five articles provided information in relation to outcomes of thyroidectomy performed with the use of sealing device versus that performed using traditional CAT technique. Of these, 27 articles were selected for final inclusion. A thorough review of available literature shows that sealing device provides better results in terms of intraoperative and postoperative blood loss, postoperative drain volume, incidence of transient or permanent palsy of recurrent laryngeal nerve and external branch of superior laryngeal nerve, postoperative transient or permanent hypocalcemia, and length of hospital stay.
本系统综述的目的是比较两种甲状腺切除术技术的结果和并发症:采用密封装置(LigaSure小颌)进行甲状腺切除术的手术技术与传统的夹扎技术(CAT)。临床研究从PubMed、EMBASE和Scopus电子数据库中检索。105篇文章提供了与使用密封装置进行甲状腺切除术与使用传统CAT技术进行甲状腺切除术的结果相关的信息。其中27篇文章最终入选。通过对现有文献的全面回顾,发现在术中、术后出血量、术后引流量、喉返神经及喉上神经外支一过性或永久性麻痹发生率、术后一过性或永久性低钙血症、住院时间等方面,封闭装置均具有较好的效果。
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引用次数: 0
Imaging advances in oral cavity cancer and perspectives from a population in need: Consensus from the UK-India oral cancer imaging group 口腔癌症的成像进展和有需要人群的观点:英国-印度口腔癌症成像小组的共识
IF 0.1 Q4 Medicine Pub Date : 2021-01-01 DOI: 10.4103/jhnps.jhnps_10_21
N. Subramaniam, Harish Poptani, A. Schache, Venkataramana Bhat, S. Iyer, H. Sunil, N. Chandrasekhar, V. Pillai, P. Chaturvedi, S. Krishna, A. Krishnamurthy, V. Kekatpure, M. Kuriakose, N. Iyer, A. Thakkar, R. Kantharia, A. Sonkar, V. Shetty, V. Rangappa, T. Kolur, S. Vidhyadharan, Samskruthi P. Murthy, A. Kudpaje, V. Srinivasalu, A. Mahajan
Oral squamous cell carcinoma (OSCC) accounts for a third of the cancer burden in India, with a correspondingly high cancer-specific mortality. Although treatment of OSCC in India mirrors that of high-income nations, extreme burden of disease, late presentation, and the associated advanced stage of disease pose unique challenges in a resource-constrained environment. Despite a multimodal treatment paradigm, survival rates are low. Often the cause for late presentation is the delayed diagnosis, inappropriate investigation and referral, and compromised or incorrect treatment, leading to poor patient outcomes and costs to the health-care provider. To address these issues, the first UK-India Symposium on Advances in Oral Cancer Imaging Symposium was organized in Bangalore, India, in April 2019; participants included radiologists, imaging scientists, clinicians, and data scientists from the United Kingdom, India, Singapore, and the United States. Following the discussions held during this meeting, in this manuscript, we present evidence-based guidance for the role of imaging in OSCC, recommendations for service development, and details of future potential for evolution in head and neck imaging.
口腔鳞状细胞癌(OSCC)占印度癌症负担的三分之一,癌症特异性死亡率相应较高。尽管印度的OSCC治疗反映了高收入国家的情况,但在资源有限的环境中,疾病的极端负担、晚期表现和相关的疾病晚期构成了独特的挑战。尽管采用了多模式治疗模式,但存活率很低。延迟就诊的原因通常是诊断延迟、调查和转诊不当、治疗受损或不正确,导致患者预后不佳,并给医疗保健提供者带来成本。为了解决这些问题,2019年4月在印度班加罗尔举办了首届英国-印度口腔癌症成像进展研讨会;参与者包括来自英国、印度、新加坡和美国的放射科医生、成像科学家、临床医生和数据科学家。在这次会议期间进行的讨论之后,在这份手稿中,我们提出了成像在OSCC中作用的循证指南、服务开发建议,以及头颈部成像未来发展潜力的细节。
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引用次数: 1
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Journal of Head & Neck Physicians and Surgeons
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