Joana Sousa Martins, Rita Ramos, Sofia Fraga, Margarida Pinto
{"title":"Intentional insulin overdose – a rare cause of hypoglycemia","authors":"Joana Sousa Martins, Rita Ramos, Sofia Fraga, Margarida Pinto","doi":"10.26497/cc210008","DOIUrl":"https://doi.org/10.26497/cc210008","url":null,"abstract":"","PeriodicalId":41840,"journal":{"name":"Revista Portuguesa de Endocrinologia Diabetes e Metabolismo","volume":null,"pages":null},"PeriodicalIF":0.1,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84601868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Joana Barreiro, Maria Joana Santos, Dália Fernandes
{"title":"Avaliação do impacto do tratamento com antivíricos de ação direta no metabolismo da glicose em doentes com infeção crónica por vírus da hepatite C","authors":"Joana Barreiro, Maria Joana Santos, Dália Fernandes","doi":"10.26497/ao210014","DOIUrl":"https://doi.org/10.26497/ao210014","url":null,"abstract":"","PeriodicalId":41840,"journal":{"name":"Revista Portuguesa de Endocrinologia Diabetes e Metabolismo","volume":null,"pages":null},"PeriodicalIF":0.1,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77674065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F. Puga, H. Simões, M. Melo, R. Attanasio, L. Hegedüs, E. Nagy, E. Papini, P. Perros, C. Freitas
{"title":"Use of thyroid hormones in hypothyroid and euthyroid patients: A THESIS questionnaire survey of Portuguese endocrinologists","authors":"F. Puga, H. Simões, M. Melo, R. Attanasio, L. Hegedüs, E. Nagy, E. Papini, P. Perros, C. Freitas","doi":"10.26497/ao210050","DOIUrl":"https://doi.org/10.26497/ao210050","url":null,"abstract":"","PeriodicalId":41840,"journal":{"name":"Revista Portuguesa de Endocrinologia Diabetes e Metabolismo","volume":null,"pages":null},"PeriodicalIF":0.1,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78610195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
José Eduardo Teixeira, José Bragada, João P Bragada, Joana Coelho, Isabel Pinto, Luís Reis, Pedro Magalhães
Introduction: Metabolic syndrome (MetS) is an independent determinant to increase the risk of metabolic and cardiovascular diseases. MetS prevalence in Portugal is high, however an update is needed since the latest Portuguese epidemiological report is from 2017. Thus, this study aims to examine MetS prevalence and its components in the adult and older Portuguese sub-population (Bragança district). Methods: A retrospective observational cross-sectional was conducted with a community sample collected from two Portuguese primary health care centres between January 2019 and December 2020. A total of 6570 individuals aged 18–102 years were included for analysis, among which 3865 women (57.37 ± 18.67 years) and 2705 men (59.97 ± 16.76 years). MetS was defined according to HARM2009 statement and binary logistic regression was performed to analyse the prevalence across sex and age. Results: MetS prevalence in Bragança district was 54.51%. MetS prevalence was higher in men (61.63%) than women (49.52%). Men are 1.53 (95% OR: 1.37–1.72, p < 0.001) times more likely of having MetS compared to women. MetS risk increases with age (OR: 2.68–42.57, p < 0.001) with a decline from the eighties onwards (OR: 27.84, 95% CI: 19.19–40.38, p < 0.001). Men presented higher prevalence of overweight (48.50%) and obesity (28.06%) and women have higher prevalence of abdominal obesity (62.07%). Conclusion: This study reported high prevalence of MetS in the Portuguese sub-population (Bra-gança district). A quasi-linear increase across age was verified in the MetS prevalence for both sexes with a decline from the eighties onwards.
简介:代谢综合征(MetS)是增加代谢和心血管疾病风险的独立决定因素。葡萄牙的met患病率很高，但由于葡萄牙最新的流行病学报告是2017年的，因此需要进行更新。因此，本研究旨在研究成人和老年葡萄牙亚人群(布拉干帕拉区)的met患病率及其组成部分。方法:对2019年1月至2020年12月期间从葡萄牙两个初级卫生保健中心收集的社区样本进行回顾性观察横断面研究。共纳入年龄在18 ~ 102岁的6570例，其中女性3865例(57.37±18.67岁)，男性2705例(59.97±16.76岁)。根据HARM2009定义MetS，并采用二元逻辑回归分析不同性别和年龄的患病率。结果:布拉干帕拉区met患病率为54.51%。met患病率男性(61.63%)高于女性(49.52%)。男性患met的可能性是女性的1.53倍(95% OR: 1.37-1.72, p < 0.001)。met风险随年龄增加而增加(OR: 2.68-42.57, p < 0.001)，从80岁开始下降(OR: 27.84, 95% CI: 19.19-40.38, p < 0.001)。男性超重(48.50%)和肥胖(28.06%)患病率较高，女性腹部肥胖(62.07%)患病率较高。结论:本研究报告了葡萄牙亚人群(bra - ganrada地区)met的高患病率。跨年龄的准线性增长证实了男女met患病率从八十年代开始下降。
{"title":"The prevalence of metabolic syndrome and its components in Bragança District, North-Eastern Portugal: A retrospective observational cross-sectional study","authors":"José Eduardo Teixeira, José Bragada, João P Bragada, Joana Coelho, Isabel Pinto, Luís Reis, Pedro Magalhães","doi":"10.26497/ao210038","DOIUrl":"https://doi.org/10.26497/ao210038","url":null,"abstract":"Introduction: Metabolic syndrome (MetS) is an independent determinant to increase the risk of metabolic and cardiovascular diseases. MetS prevalence in Portugal is high, however an update is needed since the latest Portuguese epidemiological report is from 2017. Thus, this study aims to examine MetS prevalence and its components in the adult and older Portuguese sub-population (Bragança district). Methods: A retrospective observational cross-sectional was conducted with a community sample collected from two Portuguese primary health care centres between January 2019 and December 2020. A total of 6570 individuals aged 18–102 years were included for analysis, among which 3865 women (57.37 ± 18.67 years) and 2705 men (59.97 ± 16.76 years). MetS was defined according to HARM2009 statement and binary logistic regression was performed to analyse the prevalence across sex and age. Results: MetS prevalence in Bragança district was 54.51%. MetS prevalence was higher in men (61.63%) than women (49.52%). Men are 1.53 (95% OR: 1.37–1.72, p < 0.001) times more likely of having MetS compared to women. MetS risk increases with age (OR: 2.68–42.57, p < 0.001) with a decline from the eighties onwards (OR: 27.84, 95% CI: 19.19–40.38, p < 0.001). Men presented higher prevalence of overweight (48.50%) and obesity (28.06%) and women have higher prevalence of abdominal obesity (62.07%). Conclusion: This study reported high prevalence of MetS in the Portuguese sub-population (Bra-gança district). A quasi-linear increase across age was verified in the MetS prevalence for both sexes with a decline from the eighties onwards.","PeriodicalId":41840,"journal":{"name":"Revista Portuguesa de Endocrinologia Diabetes e Metabolismo","volume":null,"pages":null},"PeriodicalIF":0.1,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74804532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J. Seabra, Rita Pereira, A. Rocha, S. Guerreiro, Henrique Candeias, Vítor Rocha, R. Eusébio, L. Cortez
{"title":"THE NON-RECURRENT LARYNGEAL NERVE: CAN WE PREDICT THIS PITFALL IN THYROID SURGERY?","authors":"J. Seabra, Rita Pereira, A. Rocha, S. Guerreiro, Henrique Candeias, Vítor Rocha, R. Eusébio, L. Cortez","doi":"10.26497/cc220007","DOIUrl":"https://doi.org/10.26497/cc220007","url":null,"abstract":"","PeriodicalId":41840,"journal":{"name":"Revista Portuguesa de Endocrinologia Diabetes e Metabolismo","volume":null,"pages":null},"PeriodicalIF":0.1,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78475251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Statins and Diabetes Mellitus - what is the link?","authors":"Filipa Machado, M. Cunha, Susana Pereira","doi":"10.26497/ar210041","DOIUrl":"https://doi.org/10.26497/ar210041","url":null,"abstract":"","PeriodicalId":41840,"journal":{"name":"Revista Portuguesa de Endocrinologia Diabetes e Metabolismo","volume":null,"pages":null},"PeriodicalIF":0.1,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75368893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Maturity-Onset Diabetes of the Young (MODY) type 6: the rarity behind the unusual.","authors":"A. Costa, H. Gonçalves, Vanessa Pires, Ana Rebelo","doi":"10.26497/cc220001","DOIUrl":"https://doi.org/10.26497/cc220001","url":null,"abstract":"","PeriodicalId":41840,"journal":{"name":"Revista Portuguesa de Endocrinologia Diabetes e Metabolismo","volume":null,"pages":null},"PeriodicalIF":0.1,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73412871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cátia Araújo, B. Araujo, M. Melo, C. Baptista, S. Paiva, I. Paiva
Introduction: Diabetes mellitus is associated with poorer outcomes in patients with coronavirus disease (COVID-19). The mechanisms for this association are not fully elucidated. We aimed to evaluate the clinical characteristics and outcomes of hospitalized patients with type 2 diabetes (T2DM) and COVID-19, as well as the impact of blood glucose control on mortality. Material and Methods: In this retrospective study, we included 97 patients (38 with T2DM, 59 without diabetes). We compared demographic characteristics, comorbidities, admission findings and outcomes between patients with and without diabetes. To assess glycaemic control, individual derived time in range (70-180 mg/dL) was derived as the proportion of values within range. Derived time above range was calculated as the proportion of values above range. Results: The fatality rate of patients with diabetes was 36.8%. Among these patients, nonsurvivors presented with higher Pneumonia Severity Index score (159 +/- 36 vs 109 +/- 30, p=0.001), a higher N-terminal brain natriuretic peptide (5521 [4256-15280] vs 1541 [288-2349] pg/mL, p=0.047), a lower PaO2/FiO2 ratio (214 [181-259] vs 300 [248-347], p=0.033) and were more likely to have bilateral lung involvement at admission (78.6% vs 29.2%, p=0.013). Rates of acute kidney injury (85.7% vs 33.3%, p=0.003), acute heart failure (57.1% vs 25.0%, p=0.048) and secondary bacterial infection (64.3 vs 26.1%, p=0.022) were higher in deceased patients. Nonsurvivors had a lower derived time in range (38% vs 73%, p=0.020) and a higher derived time above range (62% vs 27%, p=0.020). Conclusion: A poorer glucose control assessed by lower derived time in range during hospitalization was associated with in-hospital death.
糖尿病与冠状病毒病(COVID-19)患者预后较差相关。这种关联的机制尚未完全阐明。我们旨在评估2型糖尿病(T2DM)合并COVID-19住院患者的临床特征和结局，以及血糖控制对死亡率的影响。材料和方法:在这项回顾性研究中，我们纳入了97例患者(38例T2DM, 59例无糖尿病)。我们比较了糖尿病患者和非糖尿病患者的人口学特征、合并症、入院结果和结局。为了评估血糖控制情况，在范围内(70-180 mg/dL)的个体推导时间作为范围内值的比例。超出范围的导出时间以超出范围的值的比例计算。结果:糖尿病患者病死率为36.8%。在这些患者中，非幸存者表现出较高的肺炎严重程度指数评分(159 +/- 36 vs 109 +/- 30, p=0.001)，较高的n端脑利钠肽(5521 [4256-15280]vs 1541 [288-2349] pg/mL, p=0.047)，较低的PaO2/FiO2比率(214 [181-259]vs 300 [248-347]， p=0.033)，入院时更有可能累及双侧肺(78.6% vs 29.2%， p=0.013)。死亡患者的急性肾损伤(85.7% vs 33.3%， p=0.003)、急性心力衰竭(57.1% vs 25.0%， p=0.048)和继发细菌感染(64.3 vs 26.1%， p=0.022)发生率较高。非幸存者在范围内的推导时间较短(38%对73%，p=0.020)，在范围以上的推导时间较长(62%对27%，p=0.020)。结论:住院期间较差的血糖控制与院内死亡相关。
{"title":"Outcomes of hospitalized patients with type 2 diabetes and COVID-19: the impact of glycaemic control","authors":"Cátia Araújo, B. Araujo, M. Melo, C. Baptista, S. Paiva, I. Paiva","doi":"10.26497/ao210018","DOIUrl":"https://doi.org/10.26497/ao210018","url":null,"abstract":"Introduction: Diabetes mellitus is associated with poorer outcomes in patients with coronavirus disease (COVID-19). The mechanisms for this association are not fully elucidated. We aimed to evaluate the clinical characteristics and outcomes of hospitalized patients with type 2 diabetes (T2DM) and COVID-19, as well as the impact of blood glucose control on mortality. Material and Methods: In this retrospective study, we included 97 patients (38 with T2DM, 59 without diabetes). We compared demographic characteristics, comorbidities, admission findings and outcomes between patients with and without diabetes. To assess glycaemic control, individual derived time in range (70-180 mg/dL) was derived as the proportion of values within range. Derived time above range was calculated as the proportion of values above range. Results: The fatality rate of patients with diabetes was 36.8%. Among these patients, nonsurvivors presented with higher Pneumonia Severity Index score (159 +/- 36 vs 109 +/- 30, p=0.001), a higher N-terminal brain natriuretic peptide (5521 [4256-15280] vs 1541 [288-2349] pg/mL, p=0.047), a lower PaO2/FiO2 ratio (214 [181-259] vs 300 [248-347], p=0.033) and were more likely to have bilateral lung involvement at admission (78.6% vs 29.2%, p=0.013). Rates of acute kidney injury (85.7% vs 33.3%, p=0.003), acute heart failure (57.1% vs 25.0%, p=0.048) and secondary bacterial infection (64.3 vs 26.1%, p=0.022) were higher in deceased patients. Nonsurvivors had a lower derived time in range (38% vs 73%, p=0.020) and a higher derived time above range (62% vs 27%, p=0.020). Conclusion: A poorer glucose control assessed by lower derived time in range during hospitalization was associated with in-hospital death.","PeriodicalId":41840,"journal":{"name":"Revista Portuguesa de Endocrinologia Diabetes e Metabolismo","volume":null,"pages":null},"PeriodicalIF":0.1,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81174173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Metabolic and cardiovascular risk factors associated with type 1 Diabetes Mellitus in pediatric age","authors":"Mariana Araujo, Cíntia Castro Correia","doi":"10.26497/ar210013","DOIUrl":"https://doi.org/10.26497/ar210013","url":null,"abstract":"","PeriodicalId":41840,"journal":{"name":"Revista Portuguesa de Endocrinologia Diabetes e Metabolismo","volume":null,"pages":null},"PeriodicalIF":0.1,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72691719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Luísa Duarte, I. Dinis, J. Caetano, Rita M. Cardoso, Lina Aveiro, C. Gomes, Luísa Simão, Nanci Baptista, Sara Pedroso, A. Mirante
{"title":"Quality of Life of Adolescents with Type 1 Diabetes Mellitus from the Pediatric Endocrinology Unit of the Pediatric Hospital of Coimbra","authors":"Luísa Duarte, I. Dinis, J. Caetano, Rita M. Cardoso, Lina Aveiro, C. Gomes, Luísa Simão, Nanci Baptista, Sara Pedroso, A. Mirante","doi":"10.26497/ao210034","DOIUrl":"https://doi.org/10.26497/ao210034","url":null,"abstract":"","PeriodicalId":41840,"journal":{"name":"Revista Portuguesa de Endocrinologia Diabetes e Metabolismo","volume":null,"pages":null},"PeriodicalIF":0.1,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87859284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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