D. Santos, Vítor Rocha, H. Gameiro, M. Allen, D. Sousa, D. Marinho, A. Cruz, Andreia Ferreira, M. Claro, J. Martins, Pierpaolo Cusati
{"title":"Struma ovarii, an uncommon diagnosis: case-report","authors":"D. Santos, Vítor Rocha, H. Gameiro, M. Allen, D. Sousa, D. Marinho, A. Cruz, Andreia Ferreira, M. Claro, J. Martins, Pierpaolo Cusati","doi":"10.26497/cc180064","DOIUrl":"https://doi.org/10.26497/cc180064","url":null,"abstract":"","PeriodicalId":41840,"journal":{"name":"Revista Portuguesa de Endocrinologia Diabetes e Metabolismo","volume":null,"pages":null},"PeriodicalIF":0.1,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90757229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marta Alves, C. Pedrosa, C. Freitas, G. Rocha, I. Albuquerque, J. M. N. Duarte, Luís Cardoso, R. Carvalho, S. Belo, T. Azevedo, J. Silva-Nunes
{"title":"Portuguese Society for the Study of Obesity / Recommendations on Nutritional and Pharmacological Management of Diabetes After Bariatric Surgery","authors":"Marta Alves, C. Pedrosa, C. Freitas, G. Rocha, I. Albuquerque, J. M. N. Duarte, Luís Cardoso, R. Carvalho, S. Belo, T. Azevedo, J. Silva-Nunes","doi":"10.26497/na190001","DOIUrl":"https://doi.org/10.26497/na190001","url":null,"abstract":"","PeriodicalId":41840,"journal":{"name":"Revista Portuguesa de Endocrinologia Diabetes e Metabolismo","volume":null,"pages":null},"PeriodicalIF":0.1,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90105640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
B. Marques, M. Bastos, R. Martins, F. Rodrigues, F. Carrilho
{"title":"Management and Treatment of Glucocorticoid-induced Diabetes Mellitus","authors":"B. Marques, M. Bastos, R. Martins, F. Rodrigues, F. Carrilho","doi":"10.26497/ar180034","DOIUrl":"https://doi.org/10.26497/ar180034","url":null,"abstract":"","PeriodicalId":41840,"journal":{"name":"Revista Portuguesa de Endocrinologia Diabetes e Metabolismo","volume":null,"pages":null},"PeriodicalIF":0.1,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75694510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. A. Oliveira, Celestino Neves, Cesar Esteves, João Sérgio Neves, A. Oliveira, M. Pereira, Cristina Arteiro, Anabela S.G. Costa, M. Redondo, R. Baltazar, D. Carvalho
the physiological pancreatic althought is limited evidence its superiority to MDI. study to assess the effects of the transition from MDI to CSII in the intensive treatment of type 1 DM. Material and Methods: A retrospective longitudinal study was performed in MDI patients that transited to CSII between 2006 and 2014. Data were collected regarding to weight, HbA1c, plasma glucose, lipid profile, creatinine, weekly frequency of episodes of hypoglycemia and hyperglycemia and presence of microvascular complications. The effects of the transition to CSII were also com - pared according to the following subgroups: pre-CSII HbA1c (≤ 7.0% vs >7.0%); age (≤ 35 years vs > 35 years); gender (male versus female); BMI (≤25 vs >25 kg/m2); duration of illness (≤ 15 years vs > 15 years); total daily dose (TDD) of insulin (≤ 45 and > 45 units of insulin); ISF (≤ 40 and > 40) and microvascular complications (presence versus absence). Results: The sample included 85 patients, mean age 38 ± 11 years, 50 (58.8%) female, with duration of the disease 21 ± 9 years. There was a significant reduction in the frequency of hypo and hypergly - cemia events after transition to CSII (3.0 ± 5.0 vs 2 ± 2.2 per week, p = 0.001 and 5.5 ± 6.1 vs 2.5 ± 2.6 per week, p = 0.05, respectively). We also observed a greater glycemic benefit in the subgroups of patients with poorer metabolic control (HbA1c > 7%) compared to those with HbA1c ≤7% (Δ HbA1c =-0.55% vs 0.20%, respectively, p < 0.05), for the first 6 months after CSII, being addition - ally reported a significant increase in HDL-C levels (2.81 ± 10.34 mg/dL, p = 0.039). Conclusion: In this study, CSII therapy was shown to be more effective compared to MDI in pa - tients with poorer metabolic control, being also noted a significant reduction of weekly frequency of hypo and hyperglycemia events. Notwithstanding the encouraging results linked with CSII, in the future, longer longitudinal studies will be mandatory in order to assess the real relative effectiveness of CSII in the treatment of type 1 DM.
虽然生理胰的优势证据有限，但它优于MDI。研究评估从MDI到CSII过渡对1型糖尿病强化治疗的影响。材料和方法:对2006年至2014年过渡到CSII的MDI患者进行回顾性纵向研究。收集有关体重、糖化血红蛋白、血糖、血脂、肌酐、每周低血糖和高血糖发作频率以及微血管并发症的数据。还根据以下亚组比较了向CSII过渡的影响:CSII前HbA1c(≤7.0% vs >7.0%);年龄(≤35岁vs > 35岁);性别(男性vs女性);BMI(≤25 vs >25 kg/m2);病程(≤15年vs > 15年);胰岛素总日剂量(TDD)(≤45和> 45单位胰岛素);ISF(≤40和> 40)和微血管并发症(有无)。结果:85例患者，平均年龄38±11岁，女性50例(58.8%)，病程21±9年。过渡到CSII后，低血糖和高血糖事件的频率显著降低(每周3.0±5.0 vs 2±2.2,p = 0.001和5.5±6.1 vs 2.5±2.6,p = 0.05)。我们还观察到，与HbA1c≤7%的患者相比，代谢控制较差的患者亚组(HbA1c > 7%)的血糖获益更大(Δ HbA1c =-0.55% vs 0.20%，分别，p < 0.05)，在CSII后的前6个月，另外报道HDL-C水平显著升高(2.81±10.34 mg/dL, p = 0.039)。结论:在这项研究中，与MDI相比，CSII治疗在代谢控制较差的患者中更有效，并且还注意到每周低血糖和高血糖事件的频率显著降低。尽管与CSII相关的结果令人鼓舞，但在未来，为了评估CSII治疗1型糖尿病的真正相对有效性，将需要更长时间的纵向研究。
{"title":"Avaliação dos Efeitos da Transição de Múltiplas Injeções Diárias de Insulina para Infusão Subcutânea Contínua de Insulina no Tratamento Intensivo da Diabetes Mellitus Tipo 1","authors":"S. A. Oliveira, Celestino Neves, Cesar Esteves, João Sérgio Neves, A. Oliveira, M. Pereira, Cristina Arteiro, Anabela S.G. Costa, M. Redondo, R. Baltazar, D. Carvalho","doi":"10.26497/ao190004","DOIUrl":"https://doi.org/10.26497/ao190004","url":null,"abstract":"the physiological pancreatic althought is limited evidence its superiority to MDI. study to assess the effects of the transition from MDI to CSII in the intensive treatment of type 1 DM. Material and Methods: A retrospective longitudinal study was performed in MDI patients that transited to CSII between 2006 and 2014. Data were collected regarding to weight, HbA1c, plasma glucose, lipid profile, creatinine, weekly frequency of episodes of hypoglycemia and hyperglycemia and presence of microvascular complications. The effects of the transition to CSII were also com - pared according to the following subgroups: pre-CSII HbA1c (≤ 7.0% vs >7.0%); age (≤ 35 years vs > 35 years); gender (male versus female); BMI (≤25 vs >25 kg/m2); duration of illness (≤ 15 years vs > 15 years); total daily dose (TDD) of insulin (≤ 45 and > 45 units of insulin); ISF (≤ 40 and > 40) and microvascular complications (presence versus absence). Results: The sample included 85 patients, mean age 38 ± 11 years, 50 (58.8%) female, with duration of the disease 21 ± 9 years. There was a significant reduction in the frequency of hypo and hypergly - cemia events after transition to CSII (3.0 ± 5.0 vs 2 ± 2.2 per week, p = 0.001 and 5.5 ± 6.1 vs 2.5 ± 2.6 per week, p = 0.05, respectively). We also observed a greater glycemic benefit in the subgroups of patients with poorer metabolic control (HbA1c > 7%) compared to those with HbA1c ≤7% (Δ HbA1c =-0.55% vs 0.20%, respectively, p < 0.05), for the first 6 months after CSII, being addition - ally reported a significant increase in HDL-C levels (2.81 ± 10.34 mg/dL, p = 0.039). Conclusion: In this study, CSII therapy was shown to be more effective compared to MDI in pa - tients with poorer metabolic control, being also noted a significant reduction of weekly frequency of hypo and hyperglycemia events. Notwithstanding the encouraging results linked with CSII, in the future, longer longitudinal studies will be mandatory in order to assess the real relative effectiveness of CSII in the treatment of type 1 DM.","PeriodicalId":41840,"journal":{"name":"Revista Portuguesa de Endocrinologia Diabetes e Metabolismo","volume":null,"pages":null},"PeriodicalIF":0.1,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89821879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Retroperitoneal teratoma - a diferential diagnosis of adrenal adenoma","authors":"M. Laureano","doi":"10.26497/cc180038","DOIUrl":"https://doi.org/10.26497/cc180038","url":null,"abstract":"","PeriodicalId":41840,"journal":{"name":"Revista Portuguesa de Endocrinologia Diabetes e Metabolismo","volume":null,"pages":null},"PeriodicalIF":0.1,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82199860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lígia M. Ferreira, Inês Dias, Rita M. Cardoso, J. Caetano, I. Dinis, A. Mirante
{"title":"Primary Adrenal Insufficiency","authors":"Lígia M. Ferreira, Inês Dias, Rita M. Cardoso, J. Caetano, I. Dinis, A. Mirante","doi":"10.26497/ao180008","DOIUrl":"https://doi.org/10.26497/ao180008","url":null,"abstract":"","PeriodicalId":41840,"journal":{"name":"Revista Portuguesa de Endocrinologia Diabetes e Metabolismo","volume":null,"pages":null},"PeriodicalIF":0.1,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73323783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D. Martins, M. Bastos, S. Paiva, C. Baptista, Lígia M. Fonseca, Graça Santos, F. Falcão, Giselda Carvalho, S. Campos, F. Rolo, P. Temido, P. Azinhais, C. Diogo, S. Pinheiro, S. Ramos, F. Carrilho
{"title":"Endocrine approach in gender dysphoria: the experience in a reference centre","authors":"D. Martins, M. Bastos, S. Paiva, C. Baptista, Lígia M. Fonseca, Graça Santos, F. Falcão, Giselda Carvalho, S. Campos, F. Rolo, P. Temido, P. Azinhais, C. Diogo, S. Pinheiro, S. Ramos, F. Carrilho","doi":"10.26497/ao180078","DOIUrl":"https://doi.org/10.26497/ao180078","url":null,"abstract":"","PeriodicalId":41840,"journal":{"name":"Revista Portuguesa de Endocrinologia Diabetes e Metabolismo","volume":null,"pages":null},"PeriodicalIF":0.1,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80380093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-01-26DOI: 10.1016/J.RPEDM.2016.10.026
Andre Carvalho, Nena Naforna, G. Santos
{"title":"A prevalência da Diabetes Mellitus e obesidade na população adulta da Guiné-Bissau: um estudo piloto","authors":"Andre Carvalho, Nena Naforna, G. Santos","doi":"10.1016/J.RPEDM.2016.10.026","DOIUrl":"https://doi.org/10.1016/J.RPEDM.2016.10.026","url":null,"abstract":"","PeriodicalId":41840,"journal":{"name":"Revista Portuguesa de Endocrinologia Diabetes e Metabolismo","volume":null,"pages":null},"PeriodicalIF":0.1,"publicationDate":"2018-01-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79520147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-06-30DOI: 10.1016/J.RPEDM.2015.10.030
Neonatais, Alexandra Miranda, Vera Fernandes, Margarida Marquesb, Luís Castroa, Olímpia Fernandesa, Maria Lopes Pereirad
{"title":"Diabetes Gestacional: Avaliação dos Desfechos Maternos, Fetais e Neonatais","authors":"Neonatais, Alexandra Miranda, Vera Fernandes, Margarida Marquesb, Luís Castroa, Olímpia Fernandesa, Maria Lopes Pereirad","doi":"10.1016/J.RPEDM.2015.10.030","DOIUrl":"https://doi.org/10.1016/J.RPEDM.2015.10.030","url":null,"abstract":"","PeriodicalId":41840,"journal":{"name":"Revista Portuguesa de Endocrinologia Diabetes e Metabolismo","volume":null,"pages":null},"PeriodicalIF":0.1,"publicationDate":"2017-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84174266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-05-03DOI: 10.1530/endoabs.49.EP1289
António Carujo, Celestino Neves, Neves Joao Sergio, Oliveira Sofia Castro, O. Sokhatska, C. Esteves, Miguel Pereira, M. Luis, L. Delgado, D. Carvalho
Introduction: Thyroid hormones modulate the lipoprotein and glucose metabolisms. In hyperthyroidism, insulin resistance is a frequent finding. The aim of our study was to assess the interrelationships between thyroid function, autoimmunity, lipid profile, glucose metabolism and other cardiovascular risk factors in patients with Graves’ disease. Material & Methods: We recorded free T3, free T4, TSH, TSH receptor antibodies, parameters of the lipid profile, glucose metabolism (including insulin resistance markers like homeostasis model assessment for insulin resistance - HOMA-IR), C reactive protein and homocysteine in 126 patients with Graves’ disease in the first cycle of treatment with methimazole (92.9% females, mean age 44.9 ± 15.2 years). Patients were divided in subgroups according to: TSH receptor antibodies [positive (n = 57) or negative (n = 69)] and thyroid function [euthyroidism (n = 74), subclinical (n = 29) or clinical hyperthyroidism (n = 22)]. Spearman correlations, t-tests and Mann-Whitney tests were performed for statistical analysis. Results: Comparing the positive and negative TSH receptor antibodies groups, significantly lower apolipoprotein B (80.3 ± 23.9 vs 89.7 ± 23.8 mg/dL; p = 0.047) and TSH [0.180 (0.002-1.080) vs 1.020 (0.235-2.055) μUI/mL; p < 0.001] were found in the positive TSH receptor antibodies group. Comparing with the normal thyroid function group, patients in the clinical hyperthyroid group presented significantly lower apolipoprotein B (70.9 ± 25.8 vs 89.8 ± 24.0 mg/dL; p = 0.007] and higher fasting glucose (96.0 ± 24.4 vs 86.4 ± 10.0 mg/dL; p = 0.019), insulin [10.4 (6.2-15.8) vs 7.5 (4.8-9.7) μUI/mL; p = 0.021], HOMA-IR [2.09 (1.29-4.53) vs 1.55 (0.96-2.13); p = 0.023] and C reactive protein [0.57 (0.20-0.93) vs 0.20 (0.07-0.38) mg/L; p = 0.005]. No significant differences were found between the subclinical hyperthyroid and the normal groups. There was a negative correlation between TSH and the TSH receptor antibodies (r = -0.386; p < 0.001). Apolipoprotein B was positively correlated with TSH (r = 0.236; p = 0.016), and negatively with the TSH receptor antibodies (r = -0.211; p = 0.030). Both free T3 and free T4 were positively correlated with fasting insulin (r = 0.268; p = 0.008 and r = 0.226; p = 0.025, respectively) and HOMA-IR (r = 0.258; p = 0.010 and r = 0.259; p = 0.010, respectively). Free T4 was also positively correlated with fasting glucose (r = 0.269; p = 0.008). Conclusion: In patients with Graves’ disease, the interrelationships between thyroid function, autoimmunity, insulin resistance and lipid profile may contribute to the increased cardiovascular risk. The lipid profile suggests a hypolipidemic effect.
{"title":"Evaluation of interrelationships between thyroid function, autoimmunity, insulin resistance and lipid profile in Graves' disease","authors":"António Carujo, Celestino Neves, Neves Joao Sergio, Oliveira Sofia Castro, O. Sokhatska, C. Esteves, Miguel Pereira, M. Luis, L. Delgado, D. Carvalho","doi":"10.1530/endoabs.49.EP1289","DOIUrl":"https://doi.org/10.1530/endoabs.49.EP1289","url":null,"abstract":"Introduction: Thyroid hormones modulate the lipoprotein and glucose metabolisms. In hyperthyroidism, insulin resistance is a frequent finding. The aim of our study was to assess the interrelationships between thyroid function, autoimmunity, lipid profile, glucose metabolism and other cardiovascular risk factors in patients with Graves’ disease. \u0000Material & Methods: We recorded free T3, free T4, TSH, TSH receptor antibodies, parameters of the lipid profile, glucose metabolism (including insulin resistance markers like homeostasis model assessment for insulin resistance - HOMA-IR), C reactive protein and homocysteine in 126 patients with Graves’ disease in the first cycle of treatment with methimazole (92.9% females, mean age 44.9 ± 15.2 years). Patients were divided in subgroups according to: TSH receptor antibodies [positive (n = 57) or negative (n = 69)] and thyroid function [euthyroidism (n = 74), subclinical (n = 29) or clinical hyperthyroidism (n = 22)]. Spearman correlations, t-tests and Mann-Whitney tests were performed for statistical analysis. \u0000Results: Comparing the positive and negative TSH receptor antibodies groups, significantly lower apolipoprotein B (80.3 ± 23.9 vs 89.7 ± 23.8 mg/dL; p = 0.047) and TSH [0.180 (0.002-1.080) vs 1.020 (0.235-2.055) μUI/mL; p < 0.001] were found in the positive TSH receptor antibodies group. Comparing with the normal thyroid function group, patients in the clinical hyperthyroid group presented significantly lower apolipoprotein B (70.9 ± 25.8 vs 89.8 ± 24.0 mg/dL; p = 0.007] and higher fasting glucose (96.0 ± 24.4 vs 86.4 ± 10.0 mg/dL; p = 0.019), insulin [10.4 (6.2-15.8) vs 7.5 (4.8-9.7) μUI/mL; p = 0.021], HOMA-IR [2.09 (1.29-4.53) vs 1.55 (0.96-2.13); p = 0.023] and C reactive protein [0.57 (0.20-0.93) vs 0.20 (0.07-0.38) mg/L; p = 0.005]. No significant differences were found between the subclinical hyperthyroid and the normal groups. There was a negative correlation between TSH and the TSH receptor antibodies (r = -0.386; p < 0.001). Apolipoprotein B was positively correlated with TSH (r = 0.236; p = 0.016), and negatively with the TSH receptor antibodies (r = -0.211; p = 0.030). Both free T3 and free T4 were positively correlated with fasting insulin (r = 0.268; p = 0.008 and r = 0.226; p = 0.025, respectively) and HOMA-IR (r = 0.258; p = 0.010 and r = 0.259; p = 0.010, respectively). Free T4 was also positively correlated with fasting glucose (r = 0.269; p = 0.008). \u0000Conclusion: In patients with Graves’ disease, the interrelationships between thyroid function, autoimmunity, insulin resistance and lipid profile may contribute to the increased cardiovascular risk. The lipid profile suggests a hypolipidemic effect.","PeriodicalId":41840,"journal":{"name":"Revista Portuguesa de Endocrinologia Diabetes e Metabolismo","volume":null,"pages":null},"PeriodicalIF":0.1,"publicationDate":"2017-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91336869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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