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Angiotensin II type 1 receptor antibodies in kidney transplantation 肾移植中的血管紧张素II型1受体抗体
Pub Date : 2019-03-31 DOI: 10.4285/JKSTN.2019.33.1.6
Hyeyoung Lee, E. Oh
Angiotensin II type 1 receptor (AT1R) antibodies directly injure endothelial and vascular smooth muscle cells by activating transcription factors associated with proinflammatory responses. Previous studies have shown that AT1R antibodies are associated with allograft rejection and decreased graft survival in kidney transplantation. Development of enzyme-linked immunosorbent assay has facilitated semiquantitative detection of AT1R antibodies. Assessing AT1R antibodies along with donor specific human leukocyte antigen antibodies may have potential to identify patients with possible risk for allograft injury and improve overall outcomes. In this review, we summarize recent clinical studies about AT1R antibodies in kidney transplantation and provide perspectives for future research area.
血管紧张素II型1受体(AT1R)抗体通过激活与促炎反应相关的转录因子直接损伤内皮细胞和血管平滑肌细胞。先前的研究表明,AT1R抗体与肾移植中异体移植物排斥反应和移植物存活率降低有关。酶联免疫吸附法的发展促进了AT1R抗体的半定量检测。评估AT1R抗体和供体特异性人白细胞抗原抗体可能有潜力识别可能存在同种异体移植损伤风险的患者,并改善总体结果。本文就AT1R抗体在肾移植中的临床研究进展进行综述,并对今后的研究方向进行展望。
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引用次数: 0
Pediatric liver transplantation in Korea: long-term outcomes and allocations 韩国儿童肝移植:长期结果和分配
Pub Date : 2019-03-01 DOI: 10.4285/JKSTN.2019.33.1.1
Sanghoon Lee, S. Lee
Pediatric liver transplantation has evolved into an effective treatment for a variety of liver diseases in the pediatric population. Over the past 25 years, pediatric liver transplantation results in Korea have matched international standards, and Korea has become one of the most important leaders in living donor liver transplantation. This review presents the cumulative outcomes of pediatric liver transplants in Korea and highlights other concerns related to pediatric liver transplantation, particularly pediatric liver allocation policy and split liver transplantation.
儿童肝移植已发展成为一种有效的治疗多种肝脏疾病的儿科人群。在过去的25年里,韩国的儿童肝脏移植手术达到了国际水平,韩国已经成为活体肝脏移植领域的重要领导者之一。本综述介绍了韩国儿童肝移植的累积结果,并强调了与儿童肝移植相关的其他问题,特别是儿童肝脏分配政策和分离肝移植。
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引用次数: 3
A case of Castleman disease that improved after kidney transplantation 肾移植后Castleman病好转1例
Pub Date : 2019-03-01 DOI: 10.4285/JKSTN.2019.33.1.13
Heeryong Lee, J. An, D. R. Lee, Hyung Wook Choi, J. Oh, Joong-Kyung Kim
This is a case of a 56-year-old man with Castleman disease (CD) who improved after kidney transplantation (KTP). CD is an uncommon lymphoproliferative disorder that was found incidentally on biopsy during dialysis in the current patient and was followed up without further treatment. However, the lesion showed improvement after KTP. Therefore, active KTP can be considered even if CD is one of the lymphoproliferative disorders that can occur as a complication after KTP.
这是一个56岁患有Castleman病(CD)的男性,在肾移植(KTP)后病情好转。CD是一种罕见的淋巴细胞增生性疾病,在本例患者透析期间偶然发现活检,并随访,未作进一步治疗。然而,KTP后病变有所改善。因此,活动性KTP可以被考虑,即使CD是KTP后可能出现的并发症之一的淋巴增生性疾病。
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引用次数: 1
Donor Specific Antibody Negative Antibody-Mediated Rejection after ABO Incompatible Liver Transplantation ABO血型不相容肝移植后供体特异性抗体阴性抗体介导的排斥反应
Pub Date : 2018-12-31 DOI: 10.4285/JKSTN.2018.32.4.108
Boram Lee, Soomin Ahn, Haeryoung Kim, Ho-Seong Han, Yoo-Seok Yoon, J. Cho, Y. Choi
Donor Specific Antibody Negative Antibody-Mediated Rejection after ABO Incompatible Liver Transplantation Boram Lee, M.D., Soomin Ahn, M.D., Haeryoung Kim, Ph.D., Ho-Seong Han, Ph.D., Yoo-Seok Yoon, Ph.D., Jai Young Cho, Ph.D. and Young Rok Choi, M.D. Departments of Surgery and Pathology, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Department of Pathology, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea
ABO血型不相容肝移植后供体特异性抗体阴性抗体引起的排斥反应李宝兰医学博士、安秀民医学博士、金海荣医学博士、韩浩成医学博士、尹佑锡医学博士、赵宰英博士、崔永rok医学博士、首尔大学城南医学院盆唐医院外科病理科、首尔大学医学院病理科、首尔大学附属医院病理科、首尔大学附属医院病理科、首尔大学附属医院病理科、首尔大学附属医院外科病理科、首尔大学附属医院病理科、首尔大学附属医院病理科、首尔大学附属医院病理科、首尔大学附属医院病理科、首尔大学附属医院病理科、首尔大学附属医院病理科、首尔大学附属医院病理科、首尔,韩国
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引用次数: 0
Successful Treatment of Invasive Gastric Mucormycosis in a Kidney Transplant Recipient 肾移植受者侵袭性胃粘膜真菌病的成功治疗
Pub Date : 2018-12-01 DOI: 10.4285/JKSTN.2018.32.4.104
H. Kim, S. Han, H. Park, Hyun-woo Kim, R. Hong, N. Choi, M. Shin, N. Yoon, Hyun Lee Kim, J. Chung, B. Shin
Type : Poster Presentation No. : PTL 031 Successful treatment of invasive gastric mucormycosis in kidney transplant recipient Hyun Woo Kim, Ha Yeol Park, Hyun Lee Kim, Jong Hoon Chung, Byung Chul Shin Department of Internal Medicine-Nephrology, Chosun University Hospital, Korea, Republic of Case Study: Mucormycosis is an extremely rare, but potentially life-threatening fungal infection. Gastrointestinal (GI) mucormycosis is rare and occurs primarily in the extremely malnourished patients especially infants or children. A 55-year-old man with end-stage renal disease due to diabetic nephropathy underwent deceased donor kidney transplantation on 2years ago. He complained of abdominal pain and distension on 3days ago at admission. A computed tomography (CT) scan revealed diffuse gastric wall thickening. A gastrointestinal (GI) endoscopy showed huge grey colored elevated necrotic debris surrounded by erythematous erosive mucosa at antrum to upper body. Microscopic examination obtained from a GI endoscopic specimen demonstrated peptic detritus with numerous nonseptate mucor hyphae was noted in the mucosa and submucosa. Mucormycosis was diagnosed according to the clinical findings and morphological features. A total gastrectomy was performed and antifungal agent was supplied. Microscopic examination obtained from a surgical specimen demonstrated invasive mucormycosis with numerous fungal hyphae with invasion into mucosa to subserosa. The patient and graft successfully treated to the infection with total gastrectomy and antifungal therapy. GI endocscopy showed gastric mucormycosis
类型:海报展示编号肾移植受者侵袭性胃毛霉病的成功治疗金铉宇,朴河烈,金铉李,钟钟勋,申炳哲案例研究:毛霉病是一种极其罕见,但可能危及生命的真菌感染。胃肠道(GI)毛霉菌病是罕见的,主要发生在极度营养不良的患者,特别是婴儿或儿童。1例55岁男性糖尿病肾病终末期肾病患者于2年前行已故供体肾移植手术。3天前入院时主诉腹痛和腹胀。计算机断层扫描显示弥漫性胃壁增厚。胃肠道内窥镜检查显示上半身上颌窦处巨大的灰色坏死碎片被红斑糜烂粘膜包围。胃镜标本的显微镜检查显示,在粘膜和粘膜下层发现了大量不分离的粘液菌丝的消化性碎屑。根据临床表现和形态学特征诊断为毛霉病。行全胃切除术并给予抗真菌药。手术标本镜检显示侵袭性毛霉病伴大量真菌菌丝侵入粘膜至浆膜下。经全胃切除及抗真菌治疗,患者及移植物均成功治愈。胃肠道内窥镜检查显示胃粘膜真菌病
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引用次数: 1
ABO Incompatible Living Donor Liver Transplantation: A Single Center Experience ABO血型不相容活体供肝移植:单一中心经验
Pub Date : 2018-12-01 DOI: 10.4285/JKSTN.2018.32.4.84
Seung Hoon Lee, H. Choi, Y. You, D. G. Kim, G. Na
Background: This study examined the outcomes of ABO incompatible living donor liver transplantation (LDLT). The changes in the immunologic factors that might help predict the long term outcomes were also studied. Methods: Twenty-three patients, who underwent ABO incompatible LDLT from 2010 to 2015, were reviewed retrospectively. The protocol was the same as for ABO compatible LDLT except for the administration of rituximab and plasma exchange. The clinical outcomes and immunologic factors, such as isoagglutinin titer and cluster of differentiation 20+ (CD20+) lymphocyte levels were reviewed. Results: The center showed a 3-year survival of 64% with no case of antibody-mediated rejection. When transplantation-unrelated mortalities (for example, traffic accidents and myocardial infarction) were removed from statistical analysis, the 3-year survival was 77.8%. Although isoagglutinin titers continued to remain at low levels, the CD20+ lymphocyte levels recovered to the pre-Rituximab levels at postoperative one year. Conclusions: As donor shortages continue, ABO incompatible liver transplantation is a feasible method to expand the donor pool. On the other hand, caution is still needed until more long-term outcomes are reported. Because CD20+ lymphocytes are recovered with time, more immunologic studies will be needed in the future.
背景:本研究探讨ABO血型不合的活体供肝移植(LDLT)的预后。还研究了可能有助于预测长期结果的免疫因素的变化。方法:对2010 ~ 2015年23例ABO血型不合的LDLT患者进行回顾性分析。除使用利妥昔单抗和血浆置换外,治疗方案与ABO相容LDLT相同。本文对临床结果和免疫因素如异凝集素滴度和CD20+淋巴细胞水平进行了综述。结果:该中心显示3年生存率为64%,无一例抗体介导的排斥反应。当从统计分析中剔除与移植无关的死亡率(如交通事故和心肌梗死)时,3年生存率为77.8%。虽然异凝集素滴度继续保持在低水平,但术后1年CD20+淋巴细胞水平恢复到利妥昔单抗前水平。结论:在供体短缺的情况下,ABO不相容肝移植是扩大供体库的可行方法。另一方面,在更多的长期结果报告出来之前,仍然需要保持谨慎。由于CD20+淋巴细胞会随着时间的推移而恢复,未来还需要更多的免疫学研究。
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引用次数: 1
Proposal of a Selective Prophylaxis Strategy Based on Risk Factors to Prevent Early and Late Pneumocystis jirovecii Pneumonia after Renal Transplantation 基于危险因素的肾移植术后早期和晚期肺囊虫肺炎选择性预防策略的提出
Pub Date : 2018-12-01 DOI: 10.4285/JKSTN.2018.32.4.92
Ho Lee, A. Han, Chanjoong Choi, Sanghyun Ahn, S. Min, S. Min, Hajeong Lee, Y. S. Kim, J. Yang, J. Ha
Background: Currently, trimethoprim-sulfamethoxazole is used for Pneumocystis jirovecii pneumonia (PJP) prophylaxis, but it is associated with frequent adverse effects. This study evaluated the efficacy and safety of the current protocol and proposes an individualized risk-based prophylaxis protocol. Methods: The PJP incidence and risk factors during the first 6 months (early PJP) and afterwards (late PJP) was assessed in renal transplant recipients with (prophylaxis group) and without (no-prophylaxis group) 6-month PJP prophylaxis. Results: In 578 patients, there were 39 cases of PJP during a median follow-up of 51 months. Renal adverse events were encountered frequently during trimethoprim-sulfamethoxazole prophylaxis, leading to premature discontinuation. Patients without the prophylaxis had a significantly higher incidence of early PJP (n=27, 6.6%) compared to patients with the prophylaxis (n=0). The incidence of late PJP was 2.2%, without between-group differences. The factors associated with early PJP were preoperative desensitization and acute rejection within 1 month, whereas late PJP was associated with age, deceased donor transplant, and acute rejection requiring antithymocyte globulin treatment. Conclusions: Based on the simulation results of several risk-based scenarios, the authors recommend universal prophylaxis up to 6 months post-transplant and extended selective prophylaxis in patients aged ≥ 57 years and those with a transplant from deceased donors.
背景:目前,甲氧苄啶-磺胺甲恶唑用于预防乙基肺囊虫肺炎(PJP),但其不良反应频繁。本研究评估了当前方案的有效性和安全性,并提出了个体化的基于风险的预防方案。方法:对肾移植受者(预防组)和未(无预防组)6个月PJP预防的前6个月(PJP早期)和后6个月(PJP晚期)PJP发病率及危险因素进行评估。结果:在578例患者中,在51个月的中位随访期间,有39例PJP。在甲氧苄啶-磺胺甲恶唑预防期间,肾脏不良事件经常发生,导致过早停药。未采取预防措施的患者早期PJP发生率(n=27, 6.6%)明显高于采取预防措施的患者(n=0)。晚期PJP发生率为2.2%,组间无差异。与早期PJP相关的因素是术前脱敏和1个月内的急性排斥反应,而晚期PJP与年龄、已故供体移植和需要抗胸腺细胞球蛋白治疗的急性排斥反应有关。结论:基于几种基于风险情景的模拟结果,作者建议在移植后6个月进行普遍预防,并在年龄≥57岁的患者和来自已故供体的移植患者中延长选择性预防。
{"title":"Proposal of a Selective Prophylaxis Strategy Based on Risk Factors to Prevent Early and Late Pneumocystis jirovecii Pneumonia after Renal Transplantation","authors":"Ho Lee, A. Han, Chanjoong Choi, Sanghyun Ahn, S. Min, S. Min, Hajeong Lee, Y. S. Kim, J. Yang, J. Ha","doi":"10.4285/JKSTN.2018.32.4.92","DOIUrl":"https://doi.org/10.4285/JKSTN.2018.32.4.92","url":null,"abstract":"Background: Currently, trimethoprim-sulfamethoxazole is used for Pneumocystis jirovecii pneumonia (PJP) prophylaxis, but it is associated with frequent adverse effects. This study evaluated the efficacy and safety of the current protocol and proposes an individualized risk-based prophylaxis protocol. Methods: The PJP incidence and risk factors during the first 6 months (early PJP) and afterwards (late PJP) was assessed in renal transplant recipients with (prophylaxis group) and without (no-prophylaxis group) 6-month PJP prophylaxis. Results: In 578 patients, there were 39 cases of PJP during a median follow-up of 51 months. Renal adverse events were encountered frequently during trimethoprim-sulfamethoxazole prophylaxis, leading to premature discontinuation. Patients without the prophylaxis had a significantly higher incidence of early PJP (n=27, 6.6%) compared to patients with the prophylaxis (n=0). The incidence of late PJP was 2.2%, without between-group differences. The factors associated with early PJP were preoperative desensitization and acute rejection within 1 month, whereas late PJP was associated with age, deceased donor transplant, and acute rejection requiring antithymocyte globulin treatment. Conclusions: Based on the simulation results of several risk-based scenarios, the authors recommend universal prophylaxis up to 6 months post-transplant and extended selective prophylaxis in patients aged ≥ 57 years and those with a transplant from deceased donors.","PeriodicalId":420886,"journal":{"name":"The Journal of The Korean Society for Transplantation","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126345605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Monitoring of Mycophenolic Acid Trough Concentration in Kidney Transplant under Cyclosporine Is Beneficial in Reducing Acute Rejection within 1 Year 环孢素下监测肾移植患者霉酚酸谷浓度有助于减少1年内急性排斥反应
Pub Date : 2018-12-01 DOI: 10.4285/JKSTN.2018.32.4.75
J. Rhu, Kyo-Won Lee, J. Park, Sung Joo Kim
Background: This study was designed to analyze the clinical usefulness of mycophenolic acid trough concentration monitoring in kidney transplantation patients who were maintained with cyclosporine. Methods: The data of patients who underwent mycophenolic acid trough concentration monitoring after their first kidney transplant between November 2006 and August 2013 and were prescribed with cyclosporine, mycophenolate, and methylprednisolone were reviewed retrospectively. Cox analysis was used to analyze the risk factors for acute rejection within 1 year post-transplantation. Results: Among 90 patients, 41 (45.6%) achieved both the target levels of cyclosporine and mycophenolic acid, while three patients (3.3%) failed to achieve the target level of either cyclosporine or mycophenolic acid. Nine patients (10.0%) only achieved the mycophenolic acid target level and 37 patients (41.1%) only achieved the cyclosporine target level. While patients who achieved only the mycophenolic acid target concentration had no statistically increased risk compared to patients who achieved both target levels (hazard ratio [HR], 1.569; 95% confidence interval [CI], 0.316 to 7.778; P=0.581), patients who only achieved the cyclosporine target concentration showed an increased risk of rejection compared to the both achievement group (HR, 4.112; 95% CI, 1.583 to 10.683; P=0.004). Patients who had no achievement in the target levels showed significantly increased rejection risk compared to the patients who achieved both target levels (HR, 17.811; 95% CI, 3.072 to 103.28; P=0.001). Conclusions: Mycophenolic acid trough concentration monitoring combined with cyclosporine trough concentration monitoring is useful for avoiding acute cellular rejection if the first 1 year post-transplantation.
背景:本研究旨在分析霉酚酸谷浓度监测在环孢素维持肾移植患者中的临床应用。方法:回顾性分析2006年11月至2013年8月首次肾移植术后接受霉酚酸谷浓度监测并给予环孢素、霉酚酸酯和甲基强的松龙治疗的患者资料。采用Cox分析分析移植后1年内急性排斥反应的危险因素。结果:90例患者中,41例(45.6%)患者环孢素和霉酚酸均达标,3例(3.3%)患者环孢素和霉酚酸均未达标。9例(10.0%)患者仅达到霉酚酸目标水平,37例(41.1%)患者仅达到环孢素目标水平。而仅达到霉酚酸目标浓度的患者与同时达到两个目标浓度的患者相比,其风险无统计学意义上的增加(危险比[HR], 1.569;95%置信区间[CI], 0.316 ~ 7.778;P=0.581),仅达到环孢素目标浓度的患者发生排斥反应的风险高于两者均达到的组(HR, 4.112;95% CI, 1.583 ~ 10.683;P = 0.004)。与达到两个目标水平的患者相比,未达到目标水平的患者的排斥反应风险显著增加(HR, 17.811;95% CI, 3.072 ~ 103.28;P = 0.001)。结论:霉酚酸谷浓度监测联合环孢素谷浓度监测可有效避免移植后1年内的急性细胞排斥反应。
{"title":"Monitoring of Mycophenolic Acid Trough Concentration in Kidney Transplant under Cyclosporine Is Beneficial in Reducing Acute Rejection within 1 Year","authors":"J. Rhu, Kyo-Won Lee, J. Park, Sung Joo Kim","doi":"10.4285/JKSTN.2018.32.4.75","DOIUrl":"https://doi.org/10.4285/JKSTN.2018.32.4.75","url":null,"abstract":"Background: This study was designed to analyze the clinical usefulness of mycophenolic acid trough concentration monitoring in kidney transplantation patients who were maintained with cyclosporine. Methods: The data of patients who underwent mycophenolic acid trough concentration monitoring after their first kidney transplant between November 2006 and August 2013 and were prescribed with cyclosporine, mycophenolate, and methylprednisolone were reviewed retrospectively. Cox analysis was used to analyze the risk factors for acute rejection within 1 year post-transplantation. Results: Among 90 patients, 41 (45.6%) achieved both the target levels of cyclosporine and mycophenolic acid, while three patients (3.3%) failed to achieve the target level of either cyclosporine or mycophenolic acid. Nine patients (10.0%) only achieved the mycophenolic acid target level and 37 patients (41.1%) only achieved the cyclosporine target level. While patients who achieved only the mycophenolic acid target concentration had no statistically increased risk compared to patients who achieved both target levels (hazard ratio [HR], 1.569; 95% confidence interval [CI], 0.316 to 7.778; P=0.581), patients who only achieved the cyclosporine target concentration showed an increased risk of rejection compared to the both achievement group (HR, 4.112; 95% CI, 1.583 to 10.683; P=0.004). Patients who had no achievement in the target levels showed significantly increased rejection risk compared to the patients who achieved both target levels (HR, 17.811; 95% CI, 3.072 to 103.28; P=0.001). Conclusions: Mycophenolic acid trough concentration monitoring combined with cyclosporine trough concentration monitoring is useful for avoiding acute cellular rejection if the first 1 year post-transplantation.","PeriodicalId":420886,"journal":{"name":"The Journal of The Korean Society for Transplantation","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130055799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Effect of Bortezomib on the Management of Immediate Postoperative Refractory Antibody-Mediated Rejection after Kidney Transplantation 硼替佐米对肾移植术后即刻难治性抗体介导排斥反应的影响
Pub Date : 2018-09-01 DOI: 10.4285/JKSTN.2018.32.3.49
So-Jeong Kim, K. Jun, J. Hwang, B. Chung, Chul-woo Yang, I. Moon, Ji-Il Kim, Mi-hyeong Kim
The Effect of Bortezomib on the Management of Immediate Postoperative Refractory Antibody-Mediated Rejection after Kidney Transplantation So-Jeong Kim, M.D., Kang-Woong Jun, M.D., Jeong-Kye Hwang, M.D., Byung-Ha Chung, M.D., Chul-Woo Yang, M.D., In-Sung Moon, M.D., Ji-il Kim, M.D. and Mi-Hyeong Kim, M.D. Division of Vascular and Transplant Surgery, Department of Surgery, Division of Nephrology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea
Bortezomib对肾移植术后即刻难治性抗体介导的排斥反应的处理效果Kim So-Jeong, M.D., Kang-Woong Jun, M.D., Jeong-Kye Hwang, M.D., Byung-Ha Chung, M.D., Chul-Woo Yang, M.D., In-Sung Moon, M.D., Ji-il Kim, M.D.和Mi-Hyeong Kim, M.D.,韩国天主教大学医学院血管和移植外科,外科,肾脏内科,内科,首尔
{"title":"The Effect of Bortezomib on the Management of Immediate Postoperative Refractory Antibody-Mediated Rejection after Kidney Transplantation","authors":"So-Jeong Kim, K. Jun, J. Hwang, B. Chung, Chul-woo Yang, I. Moon, Ji-Il Kim, Mi-hyeong Kim","doi":"10.4285/JKSTN.2018.32.3.49","DOIUrl":"https://doi.org/10.4285/JKSTN.2018.32.3.49","url":null,"abstract":"The Effect of Bortezomib on the Management of Immediate Postoperative Refractory Antibody-Mediated Rejection after Kidney Transplantation So-Jeong Kim, M.D., Kang-Woong Jun, M.D., Jeong-Kye Hwang, M.D., Byung-Ha Chung, M.D., Chul-Woo Yang, M.D., In-Sung Moon, M.D., Ji-il Kim, M.D. and Mi-Hyeong Kim, M.D. Division of Vascular and Transplant Surgery, Department of Surgery, Division of Nephrology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea","PeriodicalId":420886,"journal":{"name":"The Journal of The Korean Society for Transplantation","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123723954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bortezomib Treatment for Refractory Antibody-Mediated Rejection Superimposed with BK Virus-Associated Nephropathy during the Progression of Recurrent C3 Glomerulonephritis 硼替佐米治疗复发性C3肾小球肾炎进展期间合并BK病毒肾病的难治性抗体介导排斥反应
Pub Date : 2018-09-01 DOI: 10.4285/JKSTN.2018.32.3.57
W. Do, Jonghyo Lee, Kyung Joo Kim, Man-Hoon Han, Hee-Yeon Jung, Ji-Young Choi, Sun-Hee Park, Yong-Lim Kim, Chan-Duck Kim, Jang-Hee Cho, Youngae Yang, Min-Ji Kim, I. Hwang, Kyu Yeun Kim, T. Yim, Yong Jin Kim
Wonseok Do, M.D., Jong-Hak Lee, M.D., Kyung Joo Kim, M.D., Man-Hoon Han, M.D., Hee-Yeon Jung, M.D., Ji-Young Choi, M.D., Sun-Hee Park, M.D., Yong-Lim Kim, M.D., Chan-Duck Kim, M.D., Jang-Hee Cho, M.D., Youngae Yang, M.D., Minjung Kim, M.D., Inryang Hwang, M.D., Kyu Yeun Kim, M.D., Taehoon Yim, M.D. and Yong-Jin Kim, M.D. Department of Internal Medicine, School of Medicine, Kyungpook National University, Department of Internal Medicine, Daegu Fatima Hospital, Department of Pathology, Yeungnam University Medical Center, Yeungnam University College of Medicine, Department of Pathology, School of Medicine, Kyungpook National University, Daegu, Korea
{"title":"Bortezomib Treatment for Refractory Antibody-Mediated Rejection Superimposed with BK Virus-Associated Nephropathy during the Progression of Recurrent C3 Glomerulonephritis","authors":"W. Do, Jonghyo Lee, Kyung Joo Kim, Man-Hoon Han, Hee-Yeon Jung, Ji-Young Choi, Sun-Hee Park, Yong-Lim Kim, Chan-Duck Kim, Jang-Hee Cho, Youngae Yang, Min-Ji Kim, I. Hwang, Kyu Yeun Kim, T. Yim, Yong Jin Kim","doi":"10.4285/JKSTN.2018.32.3.57","DOIUrl":"https://doi.org/10.4285/JKSTN.2018.32.3.57","url":null,"abstract":"Wonseok Do, M.D., Jong-Hak Lee, M.D., Kyung Joo Kim, M.D., Man-Hoon Han, M.D., Hee-Yeon Jung, M.D., Ji-Young Choi, M.D., Sun-Hee Park, M.D., Yong-Lim Kim, M.D., Chan-Duck Kim, M.D., Jang-Hee Cho, M.D., Youngae Yang, M.D., Minjung Kim, M.D., Inryang Hwang, M.D., Kyu Yeun Kim, M.D., Taehoon Yim, M.D. and Yong-Jin Kim, M.D. Department of Internal Medicine, School of Medicine, Kyungpook National University, Department of Internal Medicine, Daegu Fatima Hospital, Department of Pathology, Yeungnam University Medical Center, Yeungnam University College of Medicine, Department of Pathology, School of Medicine, Kyungpook National University, Daegu, Korea","PeriodicalId":420886,"journal":{"name":"The Journal of The Korean Society for Transplantation","volume":"79 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117221141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
The Journal of The Korean Society for Transplantation
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