{"title":"Predictor Value of PD-L1 for Radiotherapy Response in Locally Advanced Non-Small Cell Lung Cancer","authors":"V. Demircan","doi":"10.5505/tjo.2022.3523","DOIUrl":"https://doi.org/10.5505/tjo.2022.3523","url":null,"abstract":"","PeriodicalId":42117,"journal":{"name":"Turk Onkoloji Dergisi-Turkish Journal of Oncology","volume":null,"pages":null},"PeriodicalIF":0.3,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71125676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Prospective Study to Evaluate the Dosimetric Profile of Organ at Risk in Two-Field and Three-Field Left Breast Irradiation by Three-Dimensional Conformal Radiotherapy","authors":"V. Yogi","doi":"10.5505/tjo.2022.3657","DOIUrl":"https://doi.org/10.5505/tjo.2022.3657","url":null,"abstract":"","PeriodicalId":42117,"journal":{"name":"Turk Onkoloji Dergisi-Turkish Journal of Oncology","volume":null,"pages":null},"PeriodicalIF":0.3,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71126107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Radiation Therapy after Complete or Incomplete Resection of Central Neurocytomas: The Experience of Single Center","authors":"M. Dağdelen","doi":"10.5505/tjo.2022.3710","DOIUrl":"https://doi.org/10.5505/tjo.2022.3710","url":null,"abstract":"","PeriodicalId":42117,"journal":{"name":"Turk Onkoloji Dergisi-Turkish Journal of Oncology","volume":null,"pages":null},"PeriodicalIF":0.3,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71126425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Predictive Value of Dual-phase 18F-FDG PET/CT in the Assessment of Neoadjuvant Chemotherapy Response in Patients with Locally Advanced Breast Cancer: A prospective Comparative Study with Dynamic Contrast-enhanced Magnetic Resonance Imaging","authors":"O. Kupik","doi":"10.5505/tjo.2022.3701","DOIUrl":"https://doi.org/10.5505/tjo.2022.3701","url":null,"abstract":"","PeriodicalId":42117,"journal":{"name":"Turk Onkoloji Dergisi-Turkish Journal of Oncology","volume":null,"pages":null},"PeriodicalIF":0.3,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71126549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
OBJECTIVE It is known that cancer patients are more prone to infections than the general population. We aimed to describe the risk factors affecting the survival of cancer patients infected with COVID-19 and clinical findings compared with a large COVID-19 patient population without cancer diagnosis.METHODS The clinical data of 61 cancer and 558 non-patients with COVID-19 infection who applied to the emergency room were compared retrospectively. Risk factors affecting overall survival in cancer patients were analyzed.RESULTS Gender and mean age were comparable in both groups. In the entire cohort, cancer diagnosis was found to be an independent poor prognostic factor (hazard ratio [HR] = 3.09, p<0.001) among other comorbidities. In univariate analysis;lung cancer, activated partial thromboplastin time >32 seconds, INR >1.1, N-terminal-pro-B-type natriuretic peptide (NT-proBNP) >400 pg/ml, C-reactive protein >100 mg/L, and procalcitonin >0.23 ng/mL were determined as prognostic risk factors. Lung cancer (HR=5.277, p=0.012) and NT-proBNP >400 pg/ml (HR=0.139, p=0.021) were determined as independent prognostic risk factors in multivariate analysis. CONCLUSION Cancer patients with COVID-19 infection have poor survival outcomes. Lung cancer diagnosis and elevated NT-proBNP levels were identified as the most crucial prognostic risk factors in cancer patients infected with COVID-19.
目的癌症患者比一般人群更易发生感染。我们的目的是描述影响感染COVID-19的癌症患者生存的危险因素以及与未诊断为癌症的大量COVID-19患者人群的临床结果。方法回顾性比较61例肿瘤患者和558例非COVID-19感染患者的临床资料。分析影响癌症患者总体生存的危险因素。结果两组患者的性别和平均年龄具有可比性。在整个队列中，癌症诊断为独立的不良预后因素(危险比[HR] = 3.09, p32秒，INR >1.1, n -末端前b型利钠肽(NT-proBNP) >400 pg/ml, c -反应蛋白>100 mg/L，降钙素原>0.23 ng/ ml)为预后危险因素。多因素分析确定肺癌(HR=5.277, p=0.012)和NT-proBNP >400 pg/ml (HR=0.139, p=0.021)为独立预后危险因素。结论2019冠状病毒病感染的癌症患者生存结局较差。肺癌诊断和NT-proBNP水平升高被确定为感染COVID-19的癌症患者最重要的预后危险因素。
{"title":"Poor Risk Factors Affecting Cancer Patients Infected with Covid-19: A Retrospective Comparative Study from a Pandemic Hospita","authors":"F. Ferhatoğlu","doi":"10.5505/tjo.2022.3784","DOIUrl":"https://doi.org/10.5505/tjo.2022.3784","url":null,"abstract":"OBJECTIVE It is known that cancer patients are more prone to infections than the general population. We aimed to describe the risk factors affecting the survival of cancer patients infected with COVID-19 and clinical findings compared with a large COVID-19 patient population without cancer diagnosis.METHODS The clinical data of 61 cancer and 558 non-patients with COVID-19 infection who applied to the emergency room were compared retrospectively. Risk factors affecting overall survival in cancer patients were analyzed.RESULTS Gender and mean age were comparable in both groups. In the entire cohort, cancer diagnosis was found to be an independent poor prognostic factor (hazard ratio [HR] = 3.09, p<0.001) among other comorbidities. In univariate analysis;lung cancer, activated partial thromboplastin time >32 seconds, INR >1.1, N-terminal-pro-B-type natriuretic peptide (NT-proBNP) >400 pg/ml, C-reactive protein >100 mg/L, and procalcitonin >0.23 ng/mL were determined as prognostic risk factors. Lung cancer (HR=5.277, p=0.012) and NT-proBNP >400 pg/ml (HR=0.139, p=0.021) were determined as independent prognostic risk factors in multivariate analysis. CONCLUSION Cancer patients with COVID-19 infection have poor survival outcomes. Lung cancer diagnosis and elevated NT-proBNP levels were identified as the most crucial prognostic risk factors in cancer patients infected with COVID-19.","PeriodicalId":42117,"journal":{"name":"Turk Onkoloji Dergisi-Turkish Journal of Oncology","volume":null,"pages":null},"PeriodicalIF":0.3,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71126615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"New and Modern Radiotherapy Techniques to Prevent Radiation-induced Cardiotoxicity","authors":"K. Ibis","doi":"10.5505/tjo.2022.s1009","DOIUrl":"https://doi.org/10.5505/tjo.2022.s1009","url":null,"abstract":"","PeriodicalId":42117,"journal":{"name":"Turk Onkoloji Dergisi-Turkish Journal of Oncology","volume":null,"pages":null},"PeriodicalIF":0.3,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71126931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Early Effect of Radiotherapy on Serum Levels of HSP70 and S100B in Patients with Breast Cancer","authors":"E. Özer","doi":"10.5505/tjo.2022.3335","DOIUrl":"https://doi.org/10.5505/tjo.2022.3335","url":null,"abstract":"","PeriodicalId":42117,"journal":{"name":"Turk Onkoloji Dergisi-Turkish Journal of Oncology","volume":null,"pages":null},"PeriodicalIF":0.3,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71125142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Compatibility of Tumor Grades in Pre-Operative Biopsies, Frozen Sections, and Post-Operative Specimens in Patients with Endometrial Cancer","authors":"H. Hali̇s","doi":"10.5505/tjo.2022.3522","DOIUrl":"https://doi.org/10.5505/tjo.2022.3522","url":null,"abstract":"","PeriodicalId":42117,"journal":{"name":"Turk Onkoloji Dergisi-Turkish Journal of Oncology","volume":null,"pages":null},"PeriodicalIF":0.3,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71125638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Protective Role of Astaxanthin on Radiation-Related Intestinal Toxicity in Rats","authors":"E. E. Özkan","doi":"10.5505/tjo.2022.3614","DOIUrl":"https://doi.org/10.5505/tjo.2022.3614","url":null,"abstract":"","PeriodicalId":42117,"journal":{"name":"Turk Onkoloji Dergisi-Turkish Journal of Oncology","volume":null,"pages":null},"PeriodicalIF":0.3,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71126341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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