首页 > 最新文献

Veins and Lymphatics最新文献

英文 中文
Mauro Bartolo
Pub Date : 2020-09-04 DOI: 10.4081/vl.2020.9247
Marina Cestari
This paper is part of the monographic issue: ‘Did the Masters of the past know the future? History and update of Italian Phlebolymphology’ Guest editor: Alberto Macciò (Phlebology - Part I edited by G. Agus; Phlebology - Part II edited by P. Bonadeo; Lymphology edited by F. Boccardo)
这篇论文是专著《过去的大师知道未来吗?》历史和更新意大利血液学的客座编辑:阿尔贝托Macciò(血液学-第一部分由G. Agus编辑;药物学。P. Bonadeo编辑的第二部分;淋巴学(F. Boccardo编辑)
{"title":"Mauro Bartolo","authors":"Marina Cestari","doi":"10.4081/vl.2020.9247","DOIUrl":"https://doi.org/10.4081/vl.2020.9247","url":null,"abstract":"This paper is part of the monographic issue: ‘Did the Masters of the past know the future? History and update of Italian Phlebolymphology’ \u0000Guest editor: Alberto Macciò (Phlebology - Part I edited by G. Agus; Phlebology - Part II edited by P. Bonadeo; Lymphology edited by F. Boccardo)","PeriodicalId":421508,"journal":{"name":"Veins and Lymphatics","volume":"176 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116387989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Acetazolamide and SGLT2 inhibitor as potent drugs for a patient with diabetes mellitus and worsening chronic lymphedema: A case report 乙酰唑胺和SGLT2抑制剂作为有效药物治疗糖尿病合并恶化的慢性淋巴水肿1例
Pub Date : 2020-06-01 DOI: 10.4081/vl.2020.8889
H. Kataoka
Treatment of lymphedema using a pharmacologic approach is reported to have limited efficacy. Here, I report a patient with type 2 diabetes (T2DM) and acute worsening of her chronic lymphedema, in whom treatment with acetazolamide and a sodiumglucose cotransporter-2 inhibitor (SGLT2i) effectively improved the lymphedema. A 94-year-old woman, who was treated for T2DM, hyperlipidemia, and hypertension for 17 years at my hospital presented to the emergency room because of acute worsening of her chronic right leg lymphedema with increased swelling, tightness, and dull aching. A pharmacologic approach was used to treat her worsening lymphedema. Acetazolamide 500 mg/d was administered to treat the acute tissue fluid collection in the right lymphedematous leg. Ten days later, the patient’s body weight was markedly reduced by 3.2 kg, pitting in the right leg was markedly improved, and the circumference of right limb was decreased. On day 11, the glucose-lowering agent vildagliptin was switched to the SGLT2i empagliflozin 10 mg/d. On day 70, her body weight had decreased further by 2.8 kg, and the circumference of her right limb was greatly reduced compared with that under treatment with acetazolamide. Her serum chloride concentration was increased after treatment, but her hemoglobin and hematocrit values did not change during the study period. In conclusion, acetazolamide and an SGLT2i have acute diuretic effects for draining the excess tissue fluid in the lymphedematous limb without vascular contraction by enhancing vascular tonicity. Additionally, an SGLT2i may have chronic effects for reducing fat deposits in the lymphedematous limb.
用药理学方法治疗淋巴水肿据报道疗效有限。在这里,我报告了一个2型糖尿病(T2DM)患者,慢性淋巴水肿急性恶化,用乙酰唑胺和钠-葡萄糖共转运蛋白-2抑制剂(SGLT2i)治疗可有效改善淋巴水肿。一名94岁女性,在我院治疗2型糖尿病、高脂血症和高血压17年,因慢性右腿淋巴水肿急性恶化,肿胀、紧致和隐痛加重而被送往急诊室。药物治疗方法用于治疗她恶化的淋巴水肿。应用乙酰唑胺500 mg/d治疗右腿淋巴水肿急性组织液收集。10天后,患者体重明显减轻3.2 kg,右腿凹陷明显改善,右肢周长减小。第11天,降糖药物维格列汀切换为SGLT2i恩格列净10mg /d。第70天,患者体重进一步下降2.8 kg,右肢周长较乙酰唑胺治疗组明显减小。治疗后血清氯离子浓度升高,但血红蛋白和红细胞压积值在研究期间没有变化。综上所述,乙酰唑胺和SGLT2i具有急性利尿作用,通过增强血管张力,使淋巴水肿肢体的多余组织液在不收缩的情况下排出。此外,SGLT2i可能具有减少淋巴水肿肢体脂肪沉积的慢性作用。
{"title":"Acetazolamide and SGLT2 inhibitor as potent drugs for a patient with diabetes mellitus and worsening chronic lymphedema: A case report","authors":"H. Kataoka","doi":"10.4081/vl.2020.8889","DOIUrl":"https://doi.org/10.4081/vl.2020.8889","url":null,"abstract":"Treatment of lymphedema using a pharmacologic approach is reported to have limited efficacy. Here, I report a patient with type 2 diabetes (T2DM) and acute worsening of her chronic lymphedema, in whom treatment with acetazolamide and a sodiumglucose cotransporter-2 inhibitor (SGLT2i) effectively improved the lymphedema. A 94-year-old woman, who was treated for T2DM, hyperlipidemia, and hypertension for 17 years at my hospital presented to the emergency room because of acute worsening of her chronic right leg lymphedema with increased swelling, tightness, and dull aching. A pharmacologic approach was used to treat her worsening lymphedema. Acetazolamide 500 mg/d was administered to treat the acute tissue fluid collection in the right lymphedematous leg. Ten days later, the patient’s body weight was markedly reduced by 3.2 kg, pitting in the right leg was markedly improved, and the circumference of right limb was decreased. On day 11, the glucose-lowering agent vildagliptin was switched to the SGLT2i empagliflozin 10 mg/d. On day 70, her body weight had decreased further by 2.8 kg, and the circumference of her right limb was greatly reduced compared with that under treatment with acetazolamide. Her serum chloride concentration was increased after treatment, but her hemoglobin and hematocrit values did not change during the study period. In conclusion, acetazolamide and an SGLT2i have acute diuretic effects for draining the excess tissue fluid in the lymphedematous limb without vascular contraction by enhancing vascular tonicity. Additionally, an SGLT2i may have chronic effects for reducing fat deposits in the lymphedematous limb.","PeriodicalId":421508,"journal":{"name":"Veins and Lymphatics","volume":"76 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130357189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Chronic cerebrospinal venous insufficiency, ten years after. New headlights on a venous disease that enriched the vascular world 慢性脑脊髓静脉功能不全,十年后。静脉疾病的新动向丰富了血管世界
Pub Date : 2020-06-01 DOI: 10.4081/vl.2020.9053
P. Bavera
Two very recent scientific papers have re-opened a debate on a vascular issue, chronic cerebrospinal venous insufficiency (CCSVI), that apparently was sent in a corner by other trials and some Editorial hasty conclusions. The never-ending debate is still open and, perhaps, a one-year truce helped to calm waters and sort out, as by means of a sandbox, the situation from the vascular point of view. Before discussing why these recent papers have widened the path for CCSVI, some mind refreshing is mandatory, since the opinions are spread in all directions and a concise summary may help for those that are newcomers in this issue...
最近的两篇科学论文重新开启了一场关于血管问题的辩论,慢性脑脊髓静脉功能不全(CCSVI),这一问题显然被其他试验和一些编辑草率的结论推到了角落。无休无止的争论仍在继续,也许,一年的休战有助于平息局势,并通过沙盒的方式,从血管的角度理清局势。在讨论为什么这些最近的论文拓宽了CCSVI的道路之前,一些头脑清醒是必须的,因为观点是全方位的,一个简明的总结可能会帮助那些刚接触这个问题的人…
{"title":"Chronic cerebrospinal venous insufficiency, ten years after. New headlights on a venous disease that enriched the vascular world","authors":"P. Bavera","doi":"10.4081/vl.2020.9053","DOIUrl":"https://doi.org/10.4081/vl.2020.9053","url":null,"abstract":"Two very recent scientific papers have re-opened a debate on a vascular issue, chronic cerebrospinal venous insufficiency (CCSVI), that apparently was sent in a corner by other trials and some Editorial hasty conclusions. The never-ending debate is still open and, perhaps, a one-year truce helped to calm waters and sort out, as by means of a sandbox, the situation from the vascular point of view. Before discussing why these recent papers have widened the path for CCSVI, some mind refreshing is mandatory, since the opinions are spread in all directions and a concise summary may help for those that are newcomers in this issue...","PeriodicalId":421508,"journal":{"name":"Veins and Lymphatics","volume":"56 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132320919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
COVID-19 Era: Mondor’s disease and Rembrandt. What ties? COVID-19时代:蒙多病和伦勃朗。联系什么?
Pub Date : 2020-05-19 DOI: 10.4081/vl.2020.9107
G. Agus
The recent and increased number of scientific reports on venous thrombosis and venous thromboembolism induced by corona-virus, suggests to improve our level of attention because thrombophlebitis could be a clinical manifestation of COVID-19. We need to be aware also of rare varieties of venous thrombosis such as Mondor disease. The comparison between the enigmatic breast discoloration of the Bathsheba painted by Rembrandt and a case of Mondor disease observed in 2020, becomes a cultural game to improve our clinical skills in diagnosing Mondor thrombophlebitis.
最近关于冠状病毒引起的静脉血栓形成和静脉血栓栓塞的科学报道越来越多,提示我们应提高对血栓性静脉炎的重视程度,因为血栓性静脉炎可能是COVID-19的临床表现。我们还需要注意罕见的静脉血栓形成,如蒙多病。伦勃朗画的芭丝谢芭神秘的乳房变色与2020年观察到的蒙多病病例的比较,成为一种文化游戏,以提高我们诊断蒙多血栓性静脉炎的临床技能。
{"title":"COVID-19 Era: Mondor’s disease and Rembrandt. What ties?","authors":"G. Agus","doi":"10.4081/vl.2020.9107","DOIUrl":"https://doi.org/10.4081/vl.2020.9107","url":null,"abstract":"The recent and increased number of scientific reports on venous thrombosis and venous thromboembolism induced by corona-virus, suggests to improve our level of attention because thrombophlebitis could be a clinical manifestation of COVID-19. We need to be aware also of rare varieties of venous thrombosis such as Mondor disease. The comparison between the enigmatic breast discoloration of the Bathsheba painted by Rembrandt and a case of Mondor disease observed in 2020, becomes a cultural game to improve our clinical skills in diagnosing Mondor thrombophlebitis.","PeriodicalId":421508,"journal":{"name":"Veins and Lymphatics","volume":"101 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124641673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Three patterns of chronic cerebrospinal venous insufficiency in Ménière syndrome patients: Diagnosis and treatment options msamimni<e:1>综合征患者慢性脑脊髓静脉功能不全的三种类型:诊断和治疗方案
Pub Date : 2020-04-07 DOI: 10.4081/vl.2020.8758
A. Messina, G. Garofalo, Antonella Faletra, D. Piraino
Identification techniques of the three different chronic cerebrospinal venous insufficiency patterns and related treatment options are in an initial phase of evaluation and analysis. Our purpose is to describe the appropriate management, proposing a tailored approach for each one. We identified three different Ménière syndrome patients in our Audiology Department, diagnosing the corresponding chronic cerebrospinal venous insufficiency pattern by Echo-color Doppler ultrasound evaluation and treating by venous angioplasty or rehabilitative treatment according to the internal jugular and vertebral veins anomalies found in each patient. According to the pattern, after specific treatment, echo-color-Doppler control analysis revealed a normalized venous outflow correlated to Ménière symptoms reduction and/or progressive disappearance during one year follow up. An adequate analysis of venous cerebral and ear outflow and a tailored treatment may represent an effective option when chronic cerebrospinal venous insufficiency is correctly diagnosed.
三种不同慢性脑脊髓静脉功能不全模式的识别技术和相关治疗方案正处于评估和分析的初始阶段。我们的目的是描述适当的管理,为每个人提出量身定制的方法。我们在听力学科确定了3例不同类型的m 综合征患者,通过超声多普勒评估诊断相应的慢性脑脊髓静脉功能不全模式,并根据每例患者的颈内静脉和椎静脉异常进行静脉血管成形术或康复治疗。根据这种模式,经过特殊治疗后,超声彩色多普勒控制分析显示,在一年的随访期间,静脉流出正常化与msamni症状减轻和/或逐渐消失相关。当正确诊断慢性脑脊液静脉功能不全时,充分分析脑和耳静脉流出并进行量身定制的治疗可能是一种有效的选择。
{"title":"Three patterns of chronic cerebrospinal venous insufficiency in Ménière syndrome patients: Diagnosis and treatment options","authors":"A. Messina, G. Garofalo, Antonella Faletra, D. Piraino","doi":"10.4081/vl.2020.8758","DOIUrl":"https://doi.org/10.4081/vl.2020.8758","url":null,"abstract":"Identification techniques of the three different chronic cerebrospinal venous insufficiency patterns and related treatment options are in an initial phase of evaluation and analysis. Our purpose is to describe the appropriate management, proposing a tailored approach for each one. We identified three different Ménière syndrome patients in our Audiology Department, diagnosing the corresponding chronic cerebrospinal venous insufficiency pattern by Echo-color Doppler ultrasound evaluation and treating by venous angioplasty or rehabilitative treatment according to the internal jugular and vertebral veins anomalies found in each patient. According to the pattern, after specific treatment, echo-color-Doppler control analysis revealed a normalized venous outflow correlated to Ménière symptoms reduction and/or progressive disappearance during one year follow up. An adequate analysis of venous cerebral and ear outflow and a tailored treatment may represent an effective option when chronic cerebrospinal venous insufficiency is correctly diagnosed.","PeriodicalId":421508,"journal":{"name":"Veins and Lymphatics","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123892552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Technical note for post processing of jugular venous pulse, central venous pressure and velocity trace 颈静脉脉搏、中心静脉压、流速轨迹后处理技术说明
Pub Date : 2020-03-31 DOI: 10.4081/vl.2020.8268
V. Tavoni
In this paper an original reasoning about the post processing elaboration of medical studies is presented. The aim is to suggest a method to extrapolate numerical information from clinical images. The here described elaboration is referred to ultrasound examination of internal jugular veins and central venous pressure (CVP) measures. Firstly, the operator has to collect clinical images following precise indications, then specific techniques are applied to analyze the stored data and extrapolate quantifiable measures. Analyzing the studies with ImageJ software, jugular venous pulse, velocity, CVP and electrocardiogram traces can be drown in detail. Then, significant details can be highlighted using Matlab software. Finally, using R software, the traces can be cropped, aligned and synchronized together. The obtained results allow the operator to compare different kinds of traces of the same subject, or the same type of traces between a particular group of subjects. Before using these contents, everyone is invited to verify the accuracy of assumptions, calculations and conclusions.
本文对医学研究的后处理阐述进行了初步的论证。目的是提出一种从临床图像中推断数值信息的方法。这里描述的阐述是指超声检查颈内静脉和中心静脉压(CVP)的措施。首先,操作员必须根据精确的指征收集临床图像,然后应用特定的技术来分析存储的数据并推断可量化的措施。利用ImageJ软件对研究结果进行分析,可以详细地了解颈静脉脉搏、流速、CVP和心电图痕迹。然后,可以使用Matlab软件突出显示重要的细节。最后,使用R软件,可以裁剪、对齐和同步这些轨迹。所获得的结果允许操作者比较同一主体的不同类型的轨迹,或在一组特定主体之间的相同类型的轨迹。在使用这些内容之前,请大家验证假设、计算和结论的准确性。
{"title":"Technical note for post processing of jugular venous pulse, central venous pressure and velocity trace","authors":"V. Tavoni","doi":"10.4081/vl.2020.8268","DOIUrl":"https://doi.org/10.4081/vl.2020.8268","url":null,"abstract":"In this paper an original reasoning about the post processing elaboration of medical studies is presented. The aim is to suggest a method to extrapolate numerical information from clinical images. The here described elaboration is referred to ultrasound examination of internal jugular veins and central venous pressure (CVP) measures. Firstly, the operator has to collect clinical images following precise indications, then specific techniques are applied to analyze the stored data and extrapolate quantifiable measures. Analyzing the studies with ImageJ software, jugular venous pulse, velocity, CVP and electrocardiogram traces can be drown in detail. Then, significant details can be highlighted using Matlab software. Finally, using R software, the traces can be cropped, aligned and synchronized together. The obtained results allow the operator to compare different kinds of traces of the same subject, or the same type of traces between a particular group of subjects. Before using these contents, everyone is invited to verify the accuracy of assumptions, calculations and conclusions.","PeriodicalId":421508,"journal":{"name":"Veins and Lymphatics","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127062527","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Podoconiosis, a neglected lymphatic tropical disease 足癣病,一种被忽视的淋巴性热带疾病
Pub Date : 2020-03-25 DOI: 10.4081/vl.2020.8859
P. Zamboni, M. Tessari
Podoconiosis causes a painful massive swelling of the lower limbs, bilaterally and asymmetrically. It is caused by exposure to particles common in soils of volcanic origin and is second only to lymphatic filariasis as the leading cause of tropical lymphoedema. An estimated 4 million people live with podoconiosis globally in 32 potentially endemic countries. Podoconiosis is associated with positive family history of podoconiosis, bare foot, gender, poor housing condition, foot hygiene, income and educational status of the affected patients. There are also cultural barriers involved in maintaining a high epidemiology of the disease. Podoconiosis was never been prioritized either in intervention or research programmes. This may be due to the lack of resources for new health initiatives, which is a common problem in the low-income tropical countries in which this disease is present. Only Ethiopia, Cameroon, and Rwanda report podoconiosis within their routine health management information systems.We believe that comprehensive podoconiosis control strategies such as promotion of footwear and personal hygiene are urgently needed in endemic countries in the African Region. Mapping, active surveillance and a systematic approach to the monitoring of disease burden must accompany the implementation of podoconiosis control activities. Definition and epidemiology Until 20 years ago, podoconiosis was practically not described in medical literature, and the sufferers was a private matter that was not dealt with by the formal heath sector.1 Podoconiosis causes a painful massive swelling of the lower limbs, bilaterally and asymmetrically. It is caused by exposure to particles common in soils of volcanic origin and is second only to lymphatic filariasis as the leading cause of tropical lymphoedema. An estimated 4 million people live with podoconiosis globally in 32 potentially endemic countries.2 Podoconiosis is found in highland areas of tropical Africa, Central America and north-west India. In Figure 1 it well apparent the global distribution of podoconiosis.3 Despite the significance of the disease, its global distribution and epidemiology are poorly understood, according to WHO document where is reported that in many endemic countries prevalence and incidence were never investigated.2 A systematic review assessed the epidemiology of podoconiosis in 18 endemic coutries from Africa, 3 from Asia and 11 from Latin America. None of the Latin American countries reported prevalence data, although some countries are suspected to be endemic.3 In 2011 the World Health Organization (WHO) recognized podoconiosis as one of the neglected tropical diseases (NTDs) under the category of ‘other tropical conditions’.2 Subsequently Ethiopia, Rwanda and Cameroon recognized podoconiosis as a priority NTD and included it in their longterm health plans, with scarce results, yet. The peculiarity of podoconiosis Podoconiosis is really a different disease respect to lymphedema in the We
足骨病会引起双侧和不对称的下肢剧烈肿胀。它是由暴露于火山源土壤中常见的颗粒引起的,是仅次于淋巴丝虫病的热带淋巴水肿的主要原因。在全球32个可能流行足癣病的国家中,估计有400万人患有足癣病。足癣病与足癣家族史阳性、赤脚、性别、住房条件差、足卫生、收入和受教育程度有关。在保持这种疾病的高流行病学方面也存在文化障碍。足癣病从未在干预或研究规划中得到优先考虑。这可能是由于缺乏用于新的卫生举措的资源,这是存在这种疾病的低收入热带国家的一个普遍问题。只有埃塞俄比亚、喀麦隆和卢旺达在其常规健康管理信息系统中报告足癣病。我们认为,非洲区域流行国家迫切需要全面的足癣病控制战略,例如促进鞋类和个人卫生。在实施足癣病控制活动的同时,必须制定地图、积极监测和采取系统的方法来监测疾病负担。定义和流行病学直到20年前,足癣病在医学文献中几乎没有描述,患者是一个私人问题,不由正式的卫生部门处理足骨病会引起双侧和不对称的下肢剧烈肿胀。它是由暴露于火山源土壤中常见的颗粒引起的,是仅次于淋巴丝虫病的热带淋巴水肿的主要原因。在全球32个可能流行足癣病的国家中,估计有400万人患有足癣病足锥虫病见于热带非洲、中美洲和印度西北部的高地地区。在图1中,足癣的全球分布非常明显尽管该病意义重大,但根据世卫组织的文件,人们对其全球分布和流行病学知之甚少,据报道,在许多流行国家,从未调查过患病率和发病率一项系统评价评估了18个非洲、3个亚洲和11个拉丁美洲的足癣病流行病学。没有一个拉丁美洲国家报告流行率数据,尽管一些国家被怀疑是地方性的2011年,世界卫生组织(世卫组织)确认足癣病是“其他热带疾病”类别下被忽视的热带病之一随后,埃塞俄比亚、卢旺达和喀麦隆承认足癣病是一种优先的非传染性疾病,并将其纳入其长期保健计划,但收效甚微。足癣病的特点足癣病与西方国家的淋巴水肿和热带地区的淋巴丝虫病不同。足癣病是由接触红粘土引起的,是基因和环境因素之间经典的相互作用的结果。特别是,来自土壤的矿物颗粒穿透皮肤,被淋巴系统中的巨噬细胞吸收,引起血管腔的炎症和纤维化,导致淋巴排水阻塞。这导致足部和腿部水肿,随后发展为象皮病和纤维性水肿。这些变化本身是致残的,疼痛的间歇性急性淋巴管炎发作会进一步加重(图2)关于该疾病的发病机制缺乏知识,因为尚不清楚为什么在流行地区,并非所有不穿脚的人都感染足癣病。足癣病与足癣家族史阳性、足癣患者赤脚、性别、住房条件差、足部卫生、收入和文化程度有关有足骨病家族史的个体患足骨病的可能性是无足骨病家族史个体的2.81倍[AOR, 2.81 (95% CI: 1.7-4.64)]。这一发现表明存在未知的易感基因。赤脚者患足癣的概率是穿鞋者的3.26倍[AOR, 3.26 (95% CI: 2.035.25)]。这一发现支持赤脚患者个体可能允许土壤物质进入他们的身体,启动疾病的病理生理学。男性患该病的可能性是男性的3.85倍,可能与接触分布(工作活动?)不同有关。居住条件差的人群患足癣病的风险高出83% [AOR, 0.17 (95% CI: 0.10.3)],这支持了个人卫生的作用。 事实上,不经常保持足部卫生的个体患这些疾病的概率是日常生活中保持足部卫生的个体的2.68倍[AOR, 2.68 (95 CI: 1.72 4.19)]。进一步证实,低收入患者患足癣的风险增加88% [AOR, 0.12 (95% CI: 0.07-0.22)]。最后,与不识字的人相比,小学教育的人患足癣病的风险降低98% [AOR, 0.02 (95% CI: 0.01-0.04)],中等教育的人患足癣病的风险降低99% [AOR, 0.01 (95% CI: 0.005-0.02)],而高等教育的人患足癣病的风险降低99.97% [AOR, 0.003 (95% CI: 0.0010.007)]。这一发现支持了受教育程度会提高人们对足部卫生的认识。足癣病在流行国家的另一个特点与重要的通信有关:Paolo Zamboni,意大利费拉拉市费拉拉大学艾米利亚罗马涅区静脉和淋巴疾病中心主席。电话:+ 39.0532237694。电子邮件:paolozamboni@icloud.com
{"title":"Podoconiosis, a neglected lymphatic tropical disease","authors":"P. Zamboni, M. Tessari","doi":"10.4081/vl.2020.8859","DOIUrl":"https://doi.org/10.4081/vl.2020.8859","url":null,"abstract":"Podoconiosis causes a painful massive swelling of the lower limbs, bilaterally and asymmetrically. It is caused by exposure to particles common in soils of volcanic origin and is second only to lymphatic filariasis as the leading cause of tropical lymphoedema. An estimated 4 million people live with podoconiosis globally in 32 potentially endemic countries. Podoconiosis is associated with positive family history of podoconiosis, bare foot, gender, poor housing condition, foot hygiene, income and educational status of the affected patients. There are also cultural barriers involved in maintaining a high epidemiology of the disease. Podoconiosis was never been prioritized either in intervention or research programmes. This may be due to the lack of resources for new health initiatives, which is a common problem in the low-income tropical countries in which this disease is present. Only Ethiopia, Cameroon, and Rwanda report podoconiosis within their routine health management information systems.We believe that comprehensive podoconiosis control strategies such as promotion of footwear and personal hygiene are urgently needed in endemic countries in the African Region. Mapping, active surveillance and a systematic approach to the monitoring of disease burden must accompany the implementation of podoconiosis control activities. Definition and epidemiology Until 20 years ago, podoconiosis was practically not described in medical literature, and the sufferers was a private matter that was not dealt with by the formal heath sector.1 Podoconiosis causes a painful massive swelling of the lower limbs, bilaterally and asymmetrically. It is caused by exposure to particles common in soils of volcanic origin and is second only to lymphatic filariasis as the leading cause of tropical lymphoedema. An estimated 4 million people live with podoconiosis globally in 32 potentially endemic countries.2 Podoconiosis is found in highland areas of tropical Africa, Central America and north-west India. In Figure 1 it well apparent the global distribution of podoconiosis.3 Despite the significance of the disease, its global distribution and epidemiology are poorly understood, according to WHO document where is reported that in many endemic countries prevalence and incidence were never investigated.2 A systematic review assessed the epidemiology of podoconiosis in 18 endemic coutries from Africa, 3 from Asia and 11 from Latin America. None of the Latin American countries reported prevalence data, although some countries are suspected to be endemic.3 In 2011 the World Health Organization (WHO) recognized podoconiosis as one of the neglected tropical diseases (NTDs) under the category of ‘other tropical conditions’.2 Subsequently Ethiopia, Rwanda and Cameroon recognized podoconiosis as a priority NTD and included it in their longterm health plans, with scarce results, yet. The peculiarity of podoconiosis Podoconiosis is really a different disease respect to lymphedema in the We","PeriodicalId":421508,"journal":{"name":"Veins and Lymphatics","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122063392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Restless legs syndrome, anxiety, and depression in phlebology practice 不宁腿综合征,焦虑和抑郁在静脉实践
Pub Date : 2020-03-05 DOI: 10.4081/vl.2020.8672
K. Mazayshvili, K. Kiyan, A. Sukhanov, Yury A. Gustelev
The aim was to analyze the prevalence and overlapping of chronic venous disorders, restless legs syndrome, anxiety and depressive conditions. There were 582 subjects enroll; 450 (77.5%) women and 132 (22.5%) men (mean age 45.0). The examination included a physical exam with ultrasound scanning, restless legs syndrome questionnaire, and the hospital anxiety and depression scale (HADS). The prevalence of chronic venous disorders was in 82.6% subjects, restless legs syndrome 13.9%, anxiety 28% and depression 8.6%. Chronic venous disorders were more frequent in anxious patients (34%; P<0.05) vs non-anxious (25%; P<0.05). Significant interrelations between chronic venous disorders and depression were not found (P>0.05). Anxiety and depression were significantly more frequent in patients with restless leg syndrome (anxiety 54.3% vs non-anxiety 23.8%, P<0.001; depression 24.7% vs non-depression 6%, P<0.001). There were not relevant interrelations between chronic venous disorders and restless leg syndrome or anxiety/depression. Anxiety and depressive were significantly correlated with restless legs syndrome.
目的是分析慢性静脉疾病、不宁腿综合征、焦虑和抑郁状况的患病率和重叠程度。共纳入582名受试者;450名(77.5%)女性和132名(22.5%)男性(平均年龄45.0)。检查包括超声检查、不宁腿综合征问卷、医院焦虑抑郁量表(HADS)。慢性静脉疾病患病率为82.6%,不宁腿综合征患病率为13.9%,焦虑患病率为28%,抑郁患病率为8.6%。慢性静脉疾病在焦虑患者中更为常见(34%;P0.05)。焦虑和抑郁在不宁腿综合征患者中更为常见(焦虑54.3% vs非焦虑23.8%,P<0.001;抑郁症24.7% vs非抑郁症6%,P<0.001)。慢性静脉疾病与不宁腿综合征或焦虑/抑郁之间无相关关系。焦虑、抑郁与不宁腿综合征显著相关。
{"title":"Restless legs syndrome, anxiety, and depression in phlebology practice","authors":"K. Mazayshvili, K. Kiyan, A. Sukhanov, Yury A. Gustelev","doi":"10.4081/vl.2020.8672","DOIUrl":"https://doi.org/10.4081/vl.2020.8672","url":null,"abstract":"The aim was to analyze the prevalence and overlapping of chronic venous disorders, restless legs syndrome, anxiety and depressive conditions. There were 582 subjects enroll; 450 (77.5%) women and 132 (22.5%) men (mean age 45.0). The examination included a physical exam with ultrasound scanning, restless legs syndrome questionnaire, and the hospital anxiety and depression scale (HADS). The prevalence of chronic venous disorders was in 82.6% subjects, restless legs syndrome 13.9%, anxiety 28% and depression 8.6%. Chronic venous disorders were more frequent in anxious patients (34%; P<0.05) vs non-anxious (25%; P<0.05). Significant interrelations between chronic venous disorders and depression were not found (P>0.05). Anxiety and depression were significantly more frequent in patients with restless leg syndrome (anxiety 54.3% vs non-anxiety 23.8%, P<0.001; depression 24.7% vs non-depression 6%, P<0.001). There were not relevant interrelations between chronic venous disorders and restless leg syndrome or anxiety/depression. Anxiety and depressive were significantly correlated with restless legs syndrome.","PeriodicalId":421508,"journal":{"name":"Veins and Lymphatics","volume":"53 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131369921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
A topical combination of blackberry, Centella asiatica, sodium hyaluronate, vitamin E and Melilotus to relieve legs symptoms of venous insufficiency 局部组合黑莓,积雪草,透明质酸钠,维生素E和Melilotus,以减轻腿部静脉功能不全的症状
Pub Date : 2020-03-04 DOI: 10.4081/vl.2020.8465
A. Romano, A. Curcio, N. Marchitto, Paola Paparello, M. Pironti, G. Raimondi
Chronic Venous Insufficiency (CVI) is a clinical condition characterized by several legs symptoms: telangiectasias, reticular veins, varicose veins, edema, pigmentation, eczema, lipodermatosclerosis, white atrophy and ulcers. These symptoms are often associated with tired and heavy legs, leg pain, itching, legs and ankles swelling. This report analyzes the usefulness of a cream based on blackberry, Centella asiatica, sodium hyaluronate, vitamin E and Melilotus (Flavofort 1500® legs cream) to relieve leg symptoms in CVI. A group of 35 subjects (7 men and 28 women) with legs symptoms applied Flavofort 1500® legs cream on the legs, twice a day for 10 days. The symptoms were evaluated with a patient questionnaire at 4 steps: T0 (before cream application), T1 (just after first application), T2 (5 days after first application) and T3 (10 days after first application). A reduction of subjects (%) with legs symptoms was observed both after 5 day and after 10 days.
慢性静脉功能不全(CVI)是一种以几种腿部症状为特征的临床病症:毛细血管扩张、网状静脉、静脉曲张、水肿、色素沉着、湿疹、脂质皮肤硬化、白色萎缩和溃疡。这些症状通常伴随着疲倦和沉重的腿,腿痛,瘙痒,腿和脚踝肿胀。本报告分析了一种基于黑莓、积雪草、透明质酸钠、维生素E和Melilotus (flavfort 1500®腿部霜)的乳膏对缓解CVI腿部症状的有效性。有腿部症状的35名受试者(7名男性和28名女性)将Flavofort 1500®腿部霜涂抹在腿部,每天两次,持续10天。通过患者问卷分4个步骤评估症状:T0(涂抹面霜前)、T1(首次涂抹后)、T2(首次涂抹后5天)和T3(首次涂抹后10天)。5天后和10天后观察到有腿部症状的受试者减少(%)。
{"title":"A topical combination of blackberry, Centella asiatica, sodium hyaluronate, vitamin E and Melilotus to relieve legs symptoms of venous insufficiency","authors":"A. Romano, A. Curcio, N. Marchitto, Paola Paparello, M. Pironti, G. Raimondi","doi":"10.4081/vl.2020.8465","DOIUrl":"https://doi.org/10.4081/vl.2020.8465","url":null,"abstract":"Chronic Venous Insufficiency (CVI) is a clinical condition characterized by several legs symptoms: telangiectasias, reticular veins, varicose veins, edema, pigmentation, eczema, lipodermatosclerosis, white atrophy and ulcers. These symptoms are often associated with tired and heavy legs, leg pain, itching, legs and ankles swelling. This report analyzes the usefulness of a cream based on blackberry, Centella asiatica, sodium hyaluronate, vitamin E and Melilotus (Flavofort 1500® legs cream) to relieve leg symptoms in CVI. A group of 35 subjects (7 men and 28 women) with legs symptoms applied Flavofort 1500® legs cream on the legs, twice a day for 10 days. The symptoms were evaluated with a patient questionnaire at 4 steps: T0 (before cream application), T1 (just after first application), T2 (5 days after first application) and T3 (10 days after first application). A reduction of subjects (%) with legs symptoms was observed both after 5 day and after 10 days.","PeriodicalId":421508,"journal":{"name":"Veins and Lymphatics","volume":"58 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128608345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Chronic venous insufficiency and interest of adjustable compression wrap devices 慢性静脉功能不全和可调节压缩包装置的兴趣
Pub Date : 2019-11-12 DOI: 10.4081/vl.2019.8054
K. Kroeger, J. Dissemond
Adjustable compression wrap devices (ACWD) are a heterogenic group which makes it difficult to match them to individual patient in their best way, we tried to characterize these products by their technical features. We bought four different ACWD and compared them regarding construction and handling. ACWD show obvious advantages including self-management, self-application, re-adjustability and standardization of the compression therapy. Basically, all systems are one or more low stretch bandages that encircle the lower leg and adhere to itself with velcro. Some allow for a selective adjustment during the course of the application because in these systems the individual bands mutually intermesh. In others, the bandages must always be opened from proximal to distal in order to retighten individual segments. In addition only one enables the user to control the compression pressure of each segment by a built-in-pressure system. Different technical features of the four ACWDs make it difficult to compare them. For effective compression easy handling, selective adjustments and a reliable pressure control seem to be the most important aspects.
可调式压缩包装置(ACWD)是一种异质组,很难以最佳方式匹配个体患者,我们试图通过其技术特征来描述这些产品。我们购买了四种不同的ACWD,并比较了它们的结构和操作。ACWD具有自我管理、自我应用、可调整性和规范化的优势。基本上,所有的系统都是一个或多个低拉伸绷带,环绕小腿并用魔术贴粘住。有些允许在应用过程中选择性调整,因为在这些系统中,各个波段相互交织。在其他情况下,绷带必须从近端到远端打开,以便重新紧固单个节段。此外,只有一个允许用户通过内置压力系统控制每个段的压缩压力。由于四种acwd的技术特点不同,因此难以进行比较。对于有效的压缩,易于操作,选择性调整和可靠的压力控制似乎是最重要的方面。
{"title":"Chronic venous insufficiency and interest of adjustable compression wrap devices","authors":"K. Kroeger, J. Dissemond","doi":"10.4081/vl.2019.8054","DOIUrl":"https://doi.org/10.4081/vl.2019.8054","url":null,"abstract":"Adjustable compression wrap devices (ACWD) are a heterogenic group which makes it difficult to match them to individual patient in their best way, we tried to characterize these products by their technical features. We bought four different ACWD and compared them regarding construction and handling. ACWD show obvious advantages including self-management, self-application, re-adjustability and standardization of the compression therapy. Basically, all systems are one or more low stretch bandages that encircle the lower leg and adhere to itself with velcro. Some allow for a selective adjustment during the course of the application because in these systems the individual bands mutually intermesh. In others, the bandages must always be opened from proximal to distal in order to retighten individual segments. In addition only one enables the user to control the compression pressure of each segment by a built-in-pressure system. Different technical features of the four ACWDs make it difficult to compare them. For effective compression easy handling, selective adjustments and a reliable pressure control seem to be the most important aspects.","PeriodicalId":421508,"journal":{"name":"Veins and Lymphatics","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121070479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
期刊
Veins and Lymphatics
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1