This paper is part of the monographic issue: ‘Did the Masters of the past know the future? History and update of Italian Phlebolymphology’ Guest editor: Alberto Macciò (Phlebology - Part I edited by G. Agus; Phlebology - Part II edited by P. Bonadeo; Lymphology edited by F. Boccardo)
{"title":"Mauro Bartolo","authors":"Marina Cestari","doi":"10.4081/vl.2020.9247","DOIUrl":"https://doi.org/10.4081/vl.2020.9247","url":null,"abstract":"This paper is part of the monographic issue: ‘Did the Masters of the past know the future? History and update of Italian Phlebolymphology’ \u0000Guest editor: Alberto Macciò (Phlebology - Part I edited by G. Agus; Phlebology - Part II edited by P. Bonadeo; Lymphology edited by F. Boccardo)","PeriodicalId":421508,"journal":{"name":"Veins and Lymphatics","volume":"176 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116387989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Treatment of lymphedema using a pharmacologic approach is reported to have limited efficacy. Here, I report a patient with type 2 diabetes (T2DM) and acute worsening of her chronic lymphedema, in whom treatment with acetazolamide and a sodiumglucose cotransporter-2 inhibitor (SGLT2i) effectively improved the lymphedema. A 94-year-old woman, who was treated for T2DM, hyperlipidemia, and hypertension for 17 years at my hospital presented to the emergency room because of acute worsening of her chronic right leg lymphedema with increased swelling, tightness, and dull aching. A pharmacologic approach was used to treat her worsening lymphedema. Acetazolamide 500 mg/d was administered to treat the acute tissue fluid collection in the right lymphedematous leg. Ten days later, the patient’s body weight was markedly reduced by 3.2 kg, pitting in the right leg was markedly improved, and the circumference of right limb was decreased. On day 11, the glucose-lowering agent vildagliptin was switched to the SGLT2i empagliflozin 10 mg/d. On day 70, her body weight had decreased further by 2.8 kg, and the circumference of her right limb was greatly reduced compared with that under treatment with acetazolamide. Her serum chloride concentration was increased after treatment, but her hemoglobin and hematocrit values did not change during the study period. In conclusion, acetazolamide and an SGLT2i have acute diuretic effects for draining the excess tissue fluid in the lymphedematous limb without vascular contraction by enhancing vascular tonicity. Additionally, an SGLT2i may have chronic effects for reducing fat deposits in the lymphedematous limb.
{"title":"Acetazolamide and SGLT2 inhibitor as potent drugs for a patient with diabetes mellitus and worsening chronic lymphedema: A case report","authors":"H. Kataoka","doi":"10.4081/vl.2020.8889","DOIUrl":"https://doi.org/10.4081/vl.2020.8889","url":null,"abstract":"Treatment of lymphedema using a pharmacologic approach is reported to have limited efficacy. Here, I report a patient with type 2 diabetes (T2DM) and acute worsening of her chronic lymphedema, in whom treatment with acetazolamide and a sodiumglucose cotransporter-2 inhibitor (SGLT2i) effectively improved the lymphedema. A 94-year-old woman, who was treated for T2DM, hyperlipidemia, and hypertension for 17 years at my hospital presented to the emergency room because of acute worsening of her chronic right leg lymphedema with increased swelling, tightness, and dull aching. A pharmacologic approach was used to treat her worsening lymphedema. Acetazolamide 500 mg/d was administered to treat the acute tissue fluid collection in the right lymphedematous leg. Ten days later, the patient’s body weight was markedly reduced by 3.2 kg, pitting in the right leg was markedly improved, and the circumference of right limb was decreased. On day 11, the glucose-lowering agent vildagliptin was switched to the SGLT2i empagliflozin 10 mg/d. On day 70, her body weight had decreased further by 2.8 kg, and the circumference of her right limb was greatly reduced compared with that under treatment with acetazolamide. Her serum chloride concentration was increased after treatment, but her hemoglobin and hematocrit values did not change during the study period. In conclusion, acetazolamide and an SGLT2i have acute diuretic effects for draining the excess tissue fluid in the lymphedematous limb without vascular contraction by enhancing vascular tonicity. Additionally, an SGLT2i may have chronic effects for reducing fat deposits in the lymphedematous limb.","PeriodicalId":421508,"journal":{"name":"Veins and Lymphatics","volume":"76 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130357189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Two very recent scientific papers have re-opened a debate on a vascular issue, chronic cerebrospinal venous insufficiency (CCSVI), that apparently was sent in a corner by other trials and some Editorial hasty conclusions. The never-ending debate is still open and, perhaps, a one-year truce helped to calm waters and sort out, as by means of a sandbox, the situation from the vascular point of view. Before discussing why these recent papers have widened the path for CCSVI, some mind refreshing is mandatory, since the opinions are spread in all directions and a concise summary may help for those that are newcomers in this issue...
{"title":"Chronic cerebrospinal venous insufficiency, ten years after. New headlights on a venous disease that enriched the vascular world","authors":"P. Bavera","doi":"10.4081/vl.2020.9053","DOIUrl":"https://doi.org/10.4081/vl.2020.9053","url":null,"abstract":"Two very recent scientific papers have re-opened a debate on a vascular issue, chronic cerebrospinal venous insufficiency (CCSVI), that apparently was sent in a corner by other trials and some Editorial hasty conclusions. The never-ending debate is still open and, perhaps, a one-year truce helped to calm waters and sort out, as by means of a sandbox, the situation from the vascular point of view. Before discussing why these recent papers have widened the path for CCSVI, some mind refreshing is mandatory, since the opinions are spread in all directions and a concise summary may help for those that are newcomers in this issue...","PeriodicalId":421508,"journal":{"name":"Veins and Lymphatics","volume":"56 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132320919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The recent and increased number of scientific reports on venous thrombosis and venous thromboembolism induced by corona-virus, suggests to improve our level of attention because thrombophlebitis could be a clinical manifestation of COVID-19. We need to be aware also of rare varieties of venous thrombosis such as Mondor disease. The comparison between the enigmatic breast discoloration of the Bathsheba painted by Rembrandt and a case of Mondor disease observed in 2020, becomes a cultural game to improve our clinical skills in diagnosing Mondor thrombophlebitis.
{"title":"COVID-19 Era: Mondor’s disease and Rembrandt. What ties?","authors":"G. Agus","doi":"10.4081/vl.2020.9107","DOIUrl":"https://doi.org/10.4081/vl.2020.9107","url":null,"abstract":"The recent and increased number of scientific reports on venous thrombosis and venous thromboembolism induced by corona-virus, suggests to improve our level of attention because thrombophlebitis could be a clinical manifestation of COVID-19. We need to be aware also of rare varieties of venous thrombosis such as Mondor disease. The comparison between the enigmatic breast discoloration of the Bathsheba painted by Rembrandt and a case of Mondor disease observed in 2020, becomes a cultural game to improve our clinical skills in diagnosing Mondor thrombophlebitis.","PeriodicalId":421508,"journal":{"name":"Veins and Lymphatics","volume":"101 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124641673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Messina, G. Garofalo, Antonella Faletra, D. Piraino
Identification techniques of the three different chronic cerebrospinal venous insufficiency patterns and related treatment options are in an initial phase of evaluation and analysis. Our purpose is to describe the appropriate management, proposing a tailored approach for each one. We identified three different Ménière syndrome patients in our Audiology Department, diagnosing the corresponding chronic cerebrospinal venous insufficiency pattern by Echo-color Doppler ultrasound evaluation and treating by venous angioplasty or rehabilitative treatment according to the internal jugular and vertebral veins anomalies found in each patient. According to the pattern, after specific treatment, echo-color-Doppler control analysis revealed a normalized venous outflow correlated to Ménière symptoms reduction and/or progressive disappearance during one year follow up. An adequate analysis of venous cerebral and ear outflow and a tailored treatment may represent an effective option when chronic cerebrospinal venous insufficiency is correctly diagnosed.
{"title":"Three patterns of chronic cerebrospinal venous insufficiency in Ménière syndrome patients: Diagnosis and treatment options","authors":"A. Messina, G. Garofalo, Antonella Faletra, D. Piraino","doi":"10.4081/vl.2020.8758","DOIUrl":"https://doi.org/10.4081/vl.2020.8758","url":null,"abstract":"Identification techniques of the three different chronic cerebrospinal venous insufficiency patterns and related treatment options are in an initial phase of evaluation and analysis. Our purpose is to describe the appropriate management, proposing a tailored approach for each one. We identified three different Ménière syndrome patients in our Audiology Department, diagnosing the corresponding chronic cerebrospinal venous insufficiency pattern by Echo-color Doppler ultrasound evaluation and treating by venous angioplasty or rehabilitative treatment according to the internal jugular and vertebral veins anomalies found in each patient. According to the pattern, after specific treatment, echo-color-Doppler control analysis revealed a normalized venous outflow correlated to Ménière symptoms reduction and/or progressive disappearance during one year follow up. An adequate analysis of venous cerebral and ear outflow and a tailored treatment may represent an effective option when chronic cerebrospinal venous insufficiency is correctly diagnosed.","PeriodicalId":421508,"journal":{"name":"Veins and Lymphatics","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123892552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In this paper an original reasoning about the post processing elaboration of medical studies is presented. The aim is to suggest a method to extrapolate numerical information from clinical images. The here described elaboration is referred to ultrasound examination of internal jugular veins and central venous pressure (CVP) measures. Firstly, the operator has to collect clinical images following precise indications, then specific techniques are applied to analyze the stored data and extrapolate quantifiable measures. Analyzing the studies with ImageJ software, jugular venous pulse, velocity, CVP and electrocardiogram traces can be drown in detail. Then, significant details can be highlighted using Matlab software. Finally, using R software, the traces can be cropped, aligned and synchronized together. The obtained results allow the operator to compare different kinds of traces of the same subject, or the same type of traces between a particular group of subjects. Before using these contents, everyone is invited to verify the accuracy of assumptions, calculations and conclusions.
{"title":"Technical note for post processing of jugular venous pulse, central venous pressure and velocity trace","authors":"V. Tavoni","doi":"10.4081/vl.2020.8268","DOIUrl":"https://doi.org/10.4081/vl.2020.8268","url":null,"abstract":"In this paper an original reasoning about the post processing elaboration of medical studies is presented. The aim is to suggest a method to extrapolate numerical information from clinical images. The here described elaboration is referred to ultrasound examination of internal jugular veins and central venous pressure (CVP) measures. Firstly, the operator has to collect clinical images following precise indications, then specific techniques are applied to analyze the stored data and extrapolate quantifiable measures. Analyzing the studies with ImageJ software, jugular venous pulse, velocity, CVP and electrocardiogram traces can be drown in detail. Then, significant details can be highlighted using Matlab software. Finally, using R software, the traces can be cropped, aligned and synchronized together. The obtained results allow the operator to compare different kinds of traces of the same subject, or the same type of traces between a particular group of subjects. Before using these contents, everyone is invited to verify the accuracy of assumptions, calculations and conclusions.","PeriodicalId":421508,"journal":{"name":"Veins and Lymphatics","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127062527","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Podoconiosis causes a painful massive swelling of the lower limbs, bilaterally and asymmetrically. It is caused by exposure to particles common in soils of volcanic origin and is second only to lymphatic filariasis as the leading cause of tropical lymphoedema. An estimated 4 million people live with podoconiosis globally in 32 potentially endemic countries. Podoconiosis is associated with positive family history of podoconiosis, bare foot, gender, poor housing condition, foot hygiene, income and educational status of the affected patients. There are also cultural barriers involved in maintaining a high epidemiology of the disease. Podoconiosis was never been prioritized either in intervention or research programmes. This may be due to the lack of resources for new health initiatives, which is a common problem in the low-income tropical countries in which this disease is present. Only Ethiopia, Cameroon, and Rwanda report podoconiosis within their routine health management information systems.We believe that comprehensive podoconiosis control strategies such as promotion of footwear and personal hygiene are urgently needed in endemic countries in the African Region. Mapping, active surveillance and a systematic approach to the monitoring of disease burden must accompany the implementation of podoconiosis control activities. Definition and epidemiology Until 20 years ago, podoconiosis was practically not described in medical literature, and the sufferers was a private matter that was not dealt with by the formal heath sector.1 Podoconiosis causes a painful massive swelling of the lower limbs, bilaterally and asymmetrically. It is caused by exposure to particles common in soils of volcanic origin and is second only to lymphatic filariasis as the leading cause of tropical lymphoedema. An estimated 4 million people live with podoconiosis globally in 32 potentially endemic countries.2 Podoconiosis is found in highland areas of tropical Africa, Central America and north-west India. In Figure 1 it well apparent the global distribution of podoconiosis.3 Despite the significance of the disease, its global distribution and epidemiology are poorly understood, according to WHO document where is reported that in many endemic countries prevalence and incidence were never investigated.2 A systematic review assessed the epidemiology of podoconiosis in 18 endemic coutries from Africa, 3 from Asia and 11 from Latin America. None of the Latin American countries reported prevalence data, although some countries are suspected to be endemic.3 In 2011 the World Health Organization (WHO) recognized podoconiosis as one of the neglected tropical diseases (NTDs) under the category of ‘other tropical conditions’.2 Subsequently Ethiopia, Rwanda and Cameroon recognized podoconiosis as a priority NTD and included it in their longterm health plans, with scarce results, yet. The peculiarity of podoconiosis Podoconiosis is really a different disease respect to lymphedema in the We
{"title":"Podoconiosis, a neglected lymphatic tropical disease","authors":"P. Zamboni, M. Tessari","doi":"10.4081/vl.2020.8859","DOIUrl":"https://doi.org/10.4081/vl.2020.8859","url":null,"abstract":"Podoconiosis causes a painful massive swelling of the lower limbs, bilaterally and asymmetrically. It is caused by exposure to particles common in soils of volcanic origin and is second only to lymphatic filariasis as the leading cause of tropical lymphoedema. An estimated 4 million people live with podoconiosis globally in 32 potentially endemic countries. Podoconiosis is associated with positive family history of podoconiosis, bare foot, gender, poor housing condition, foot hygiene, income and educational status of the affected patients. There are also cultural barriers involved in maintaining a high epidemiology of the disease. Podoconiosis was never been prioritized either in intervention or research programmes. This may be due to the lack of resources for new health initiatives, which is a common problem in the low-income tropical countries in which this disease is present. Only Ethiopia, Cameroon, and Rwanda report podoconiosis within their routine health management information systems.We believe that comprehensive podoconiosis control strategies such as promotion of footwear and personal hygiene are urgently needed in endemic countries in the African Region. Mapping, active surveillance and a systematic approach to the monitoring of disease burden must accompany the implementation of podoconiosis control activities. Definition and epidemiology Until 20 years ago, podoconiosis was practically not described in medical literature, and the sufferers was a private matter that was not dealt with by the formal heath sector.1 Podoconiosis causes a painful massive swelling of the lower limbs, bilaterally and asymmetrically. It is caused by exposure to particles common in soils of volcanic origin and is second only to lymphatic filariasis as the leading cause of tropical lymphoedema. An estimated 4 million people live with podoconiosis globally in 32 potentially endemic countries.2 Podoconiosis is found in highland areas of tropical Africa, Central America and north-west India. In Figure 1 it well apparent the global distribution of podoconiosis.3 Despite the significance of the disease, its global distribution and epidemiology are poorly understood, according to WHO document where is reported that in many endemic countries prevalence and incidence were never investigated.2 A systematic review assessed the epidemiology of podoconiosis in 18 endemic coutries from Africa, 3 from Asia and 11 from Latin America. None of the Latin American countries reported prevalence data, although some countries are suspected to be endemic.3 In 2011 the World Health Organization (WHO) recognized podoconiosis as one of the neglected tropical diseases (NTDs) under the category of ‘other tropical conditions’.2 Subsequently Ethiopia, Rwanda and Cameroon recognized podoconiosis as a priority NTD and included it in their longterm health plans, with scarce results, yet. The peculiarity of podoconiosis Podoconiosis is really a different disease respect to lymphedema in the We","PeriodicalId":421508,"journal":{"name":"Veins and Lymphatics","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122063392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K. Mazayshvili, K. Kiyan, A. Sukhanov, Yury A. Gustelev
The aim was to analyze the prevalence and overlapping of chronic venous disorders, restless legs syndrome, anxiety and depressive conditions. There were 582 subjects enroll; 450 (77.5%) women and 132 (22.5%) men (mean age 45.0). The examination included a physical exam with ultrasound scanning, restless legs syndrome questionnaire, and the hospital anxiety and depression scale (HADS). The prevalence of chronic venous disorders was in 82.6% subjects, restless legs syndrome 13.9%, anxiety 28% and depression 8.6%. Chronic venous disorders were more frequent in anxious patients (34%; P<0.05) vs non-anxious (25%; P<0.05). Significant interrelations between chronic venous disorders and depression were not found (P>0.05). Anxiety and depression were significantly more frequent in patients with restless leg syndrome (anxiety 54.3% vs non-anxiety 23.8%, P<0.001; depression 24.7% vs non-depression 6%, P<0.001). There were not relevant interrelations between chronic venous disorders and restless leg syndrome or anxiety/depression. Anxiety and depressive were significantly correlated with restless legs syndrome.
{"title":"Restless legs syndrome, anxiety, and depression in phlebology practice","authors":"K. Mazayshvili, K. Kiyan, A. Sukhanov, Yury A. Gustelev","doi":"10.4081/vl.2020.8672","DOIUrl":"https://doi.org/10.4081/vl.2020.8672","url":null,"abstract":"The aim was to analyze the prevalence and overlapping of chronic venous disorders, restless legs syndrome, anxiety and depressive conditions. There were 582 subjects enroll; 450 (77.5%) women and 132 (22.5%) men (mean age 45.0). The examination included a physical exam with ultrasound scanning, restless legs syndrome questionnaire, and the hospital anxiety and depression scale (HADS). The prevalence of chronic venous disorders was in 82.6% subjects, restless legs syndrome 13.9%, anxiety 28% and depression 8.6%. Chronic venous disorders were more frequent in anxious patients (34%; P<0.05) vs non-anxious (25%; P<0.05). Significant interrelations between chronic venous disorders and depression were not found (P>0.05). Anxiety and depression were significantly more frequent in patients with restless leg syndrome (anxiety 54.3% vs non-anxiety 23.8%, P<0.001; depression 24.7% vs non-depression 6%, P<0.001). There were not relevant interrelations between chronic venous disorders and restless leg syndrome or anxiety/depression. Anxiety and depressive were significantly correlated with restless legs syndrome.","PeriodicalId":421508,"journal":{"name":"Veins and Lymphatics","volume":"53 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131369921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Romano, A. Curcio, N. Marchitto, Paola Paparello, M. Pironti, G. Raimondi
Chronic Venous Insufficiency (CVI) is a clinical condition characterized by several legs symptoms: telangiectasias, reticular veins, varicose veins, edema, pigmentation, eczema, lipodermatosclerosis, white atrophy and ulcers. These symptoms are often associated with tired and heavy legs, leg pain, itching, legs and ankles swelling. This report analyzes the usefulness of a cream based on blackberry, Centella asiatica, sodium hyaluronate, vitamin E and Melilotus (Flavofort 1500® legs cream) to relieve leg symptoms in CVI. A group of 35 subjects (7 men and 28 women) with legs symptoms applied Flavofort 1500® legs cream on the legs, twice a day for 10 days. The symptoms were evaluated with a patient questionnaire at 4 steps: T0 (before cream application), T1 (just after first application), T2 (5 days after first application) and T3 (10 days after first application). A reduction of subjects (%) with legs symptoms was observed both after 5 day and after 10 days.
{"title":"A topical combination of blackberry, Centella asiatica, sodium hyaluronate, vitamin E and Melilotus to relieve legs symptoms of venous insufficiency","authors":"A. Romano, A. Curcio, N. Marchitto, Paola Paparello, M. Pironti, G. Raimondi","doi":"10.4081/vl.2020.8465","DOIUrl":"https://doi.org/10.4081/vl.2020.8465","url":null,"abstract":"Chronic Venous Insufficiency (CVI) is a clinical condition characterized by several legs symptoms: telangiectasias, reticular veins, varicose veins, edema, pigmentation, eczema, lipodermatosclerosis, white atrophy and ulcers. These symptoms are often associated with tired and heavy legs, leg pain, itching, legs and ankles swelling. This report analyzes the usefulness of a cream based on blackberry, Centella asiatica, sodium hyaluronate, vitamin E and Melilotus (Flavofort 1500® legs cream) to relieve leg symptoms in CVI. A group of 35 subjects (7 men and 28 women) with legs symptoms applied Flavofort 1500® legs cream on the legs, twice a day for 10 days. The symptoms were evaluated with a patient questionnaire at 4 steps: T0 (before cream application), T1 (just after first application), T2 (5 days after first application) and T3 (10 days after first application). A reduction of subjects (%) with legs symptoms was observed both after 5 day and after 10 days.","PeriodicalId":421508,"journal":{"name":"Veins and Lymphatics","volume":"58 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128608345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Adjustable compression wrap devices (ACWD) are a heterogenic group which makes it difficult to match them to individual patient in their best way, we tried to characterize these products by their technical features. We bought four different ACWD and compared them regarding construction and handling. ACWD show obvious advantages including self-management, self-application, re-adjustability and standardization of the compression therapy. Basically, all systems are one or more low stretch bandages that encircle the lower leg and adhere to itself with velcro. Some allow for a selective adjustment during the course of the application because in these systems the individual bands mutually intermesh. In others, the bandages must always be opened from proximal to distal in order to retighten individual segments. In addition only one enables the user to control the compression pressure of each segment by a built-in-pressure system. Different technical features of the four ACWDs make it difficult to compare them. For effective compression easy handling, selective adjustments and a reliable pressure control seem to be the most important aspects.
{"title":"Chronic venous insufficiency and interest of adjustable compression wrap devices","authors":"K. Kroeger, J. Dissemond","doi":"10.4081/vl.2019.8054","DOIUrl":"https://doi.org/10.4081/vl.2019.8054","url":null,"abstract":"Adjustable compression wrap devices (ACWD) are a heterogenic group which makes it difficult to match them to individual patient in their best way, we tried to characterize these products by their technical features. We bought four different ACWD and compared them regarding construction and handling. ACWD show obvious advantages including self-management, self-application, re-adjustability and standardization of the compression therapy. Basically, all systems are one or more low stretch bandages that encircle the lower leg and adhere to itself with velcro. Some allow for a selective adjustment during the course of the application because in these systems the individual bands mutually intermesh. In others, the bandages must always be opened from proximal to distal in order to retighten individual segments. In addition only one enables the user to control the compression pressure of each segment by a built-in-pressure system. Different technical features of the four ACWDs make it difficult to compare them. For effective compression easy handling, selective adjustments and a reliable pressure control seem to be the most important aspects.","PeriodicalId":421508,"journal":{"name":"Veins and Lymphatics","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121070479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}