Pub Date : 2018-10-24DOI: 10.22201/fesi.20072082.2018.11.64007
Norberto Alarcón-Herrera, Saúl Flores-Maya
Seizures are one of the most common neural disorders, and may be sporadic or recurrent (epilepsy) crisis. In the case of people with epilepsy, these must be treated throughout their lives, being a major phenytoin prescription for seizure control medicines out. However, despite having several decades in the market there is very little information about their genotoxic effects. Therefore in this study to evaluate the ability of phenytoin to induce genotoxic damage for 30 days using the micronucleus test in mice Mus musculus CD-1 strain. It was determined that the three doses of phenytoin used (2.8, 4.2 and 6.64 mg/kg) induced clastogenicity in mouse chromosomes, that at higher doses the damage is greater. Furthermore, also inhibiting cytotoxic damage induced cell kinetics for doses of 4.2 and 6.64 mg/kg.
{"title":"PHENYTOIN SODIUM INDUCED MICRONUCLEI IN THE POLYCHROMATIC ERYTHROCYTES OF CD-1 MOUSE PERIPHERAL BLOOD","authors":"Norberto Alarcón-Herrera, Saúl Flores-Maya","doi":"10.22201/fesi.20072082.2018.11.64007","DOIUrl":"https://doi.org/10.22201/fesi.20072082.2018.11.64007","url":null,"abstract":"Seizures are one of the most common neural disorders, and may be sporadic or recurrent (epilepsy) crisis. In the case of people with epilepsy, these must be treated throughout their lives, being a major phenytoin prescription for seizure control medicines out. However, despite having several decades in the market there is very little information about their genotoxic effects. Therefore in this study to evaluate the ability of phenytoin to induce genotoxic damage for 30 days using the micronucleus test in mice Mus musculus CD-1 strain. It was determined that the three doses of phenytoin used (2.8, 4.2 and 6.64 mg/kg) induced clastogenicity in mouse chromosomes, that at higher doses the damage is greater. Furthermore, also inhibiting cytotoxic damage induced cell kinetics for doses of 4.2 and 6.64 mg/kg.","PeriodicalId":422823,"journal":{"name":"BIOCYT Biología Ciencia y Tecnología","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126650873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-10-24DOI: 10.22201/fesi.20072082.2018.11.67517
Enrique Antonio-Hernández, M. D. J. García-Ramírez, Diana Fong-Lara
Five species of the genus Anastrepha Schiner are reported for the first time from the region of the Isthmus of Tehuantepec, Oaxaca. A. bezzii Lima, A. minuta Stone, A. tumida Stone, A. furcata Lima and A. sp. new species, of which last two are new records for Mexico. Some taxonomic aspects are discussed, as well as the relationship of the ecosystems present in the Isthmus of Tehuantepec with the vegetal communities of the Southern Hemisphere, possible diversification patterns of the species present in this region and their relationship with their congeners of Central and South America. With these new reports the number of Anastrepha species recorded in this state increased to 27.
{"title":"NEW RECORDS OF THE GENUS ANASTREPHA SCHINER, 1868 (DIPTERA: TEPHRITIDAE) IN THE ISTHMUS OF TEHUANTEPEC, OAXACA, MEXICO","authors":"Enrique Antonio-Hernández, M. D. J. García-Ramírez, Diana Fong-Lara","doi":"10.22201/fesi.20072082.2018.11.67517","DOIUrl":"https://doi.org/10.22201/fesi.20072082.2018.11.67517","url":null,"abstract":"<p>Five species of the genus <em>Anastrepha</em> Schiner are reported for the first time from the region of the Isthmus of Tehuantepec, Oaxaca. <em>A. bezzii</em> Lima, <em>A. minuta</em> Stone, <em>A. tumida</em> Stone, <em>A. furcata</em> Lima and <em>A.</em> sp. new species<em>, </em>of which last two are new records for Mexico. Some taxonomic aspects are discussed, as well as the relationship of the ecosystems present in the Isthmus of Tehuantepec with the vegetal communities of the Southern Hemisphere, possible diversification patterns of the species present in this region and their relationship with their congeners of Central and South America. With these new reports the number of <em>Anastrepha</em> species recorded in this state increased to 27.</p>","PeriodicalId":422823,"journal":{"name":"BIOCYT Biología Ciencia y Tecnología","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129001178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-10-24DOI: 10.22201/FESI.20072082.2018.11.64003
Javier Efraín Rubio-Miranda
A population of C. acutus was studied in the Natural Protected Area “Estero el Salado” in Puerto Vallarta, Jalisco, México, among november of 2015 and september of 2016. The population abundance was evaluated and the age structure, mortality rate and growth rate were analized. Five samplings were performed in November, December, March, April and September, in order to carry on the species monitoring, finding an abundance of 15.74 ind/km SD ± 6.65, and the neonates population’s mortality rate, which showed constant values, increasing the neonates survivorship. As well the age structure was analized and it was consisted of 62.5% neonates, 28.5 juveniles and 9% sub-adults, without presence of adults, subsequently catches of the organisms were made in order to measure the total lenght of crocodiles, and thereby obtain the growth rate, wich was between 0.12 y 0.17 cm/day. This is the first study that analized the mortality rate of C. acutus neonates in a mangrove swamp, therefore this information could be used to perform better conservation strategies.
2015年11月至2016年9月，在墨西哥哈利斯科州巴亚尔塔港(Puerto Vallarta)的“Estero el Salado”自然保护区研究了一个尖刺库蚊种群。对种群丰度进行了评价，并对年龄结构、死亡率和生长率进行了分析。11月、12月、3月、4月和9月共5次取样，进行物种监测，丰度为15.74 ind/km SD±6.65，新生儿种群死亡率呈恒定值，提高了新生儿存活率。分析了幼鳄的年龄结构，幼鳄占62.5%，幼鳄占28.5%，亚成虫占9%，无成虫存在。随后对鳄鱼进行捕获，测量鳄鱼的总长度，从而得出鳄鱼的生长速度为0.12 ~ 0.17 cm/d。这是第一个分析红树沼泽中尖尖杉树幼崽死亡率的研究，因此这些信息可以用来执行更好的保护策略。
{"title":"POPULATION ASPECTS OF CROCODYLUS ACUTUS (REPTILIA: CROCODYLIDAE) IN THE ESTUARY EL SALADO, PUERTO VALLARTA JALISCO, MEXICO","authors":"Javier Efraín Rubio-Miranda","doi":"10.22201/FESI.20072082.2018.11.64003","DOIUrl":"https://doi.org/10.22201/FESI.20072082.2018.11.64003","url":null,"abstract":"A population of C. acutus was studied in the Natural Protected Area “Estero el Salado” in Puerto Vallarta, Jalisco, México, among november of 2015 and september of 2016. The population abundance was evaluated and the age structure, mortality rate and growth rate were analized. Five samplings were performed in November, December, March, April and September, in order to carry on the species monitoring, finding an abundance of 15.74 ind/km SD ± 6.65, and the neonates population’s mortality rate, which showed constant values, increasing the neonates survivorship. As well the age structure was analized and it was consisted of 62.5% neonates, 28.5 juveniles and 9% sub-adults, without presence of adults, subsequently catches of the organisms were made in order to measure the total lenght of crocodiles, and thereby obtain the growth rate, wich was between 0.12 y 0.17 cm/day. This is the first study that analized the mortality rate of C. acutus neonates in a mangrove swamp, therefore this information could be used to perform better conservation strategies.","PeriodicalId":422823,"journal":{"name":"BIOCYT Biología Ciencia y Tecnología","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132508330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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