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A study of malaria in West Bengal 西孟加拉邦的疟疾研究
Pub Date : 2023-01-01 DOI: 10.4103/ajoim.ajoim_21_22
Arvind Nath
Background: Malaria still occurs in West Bengal which is one of the states in the eastern part of India. Materials and Methods: The study design included an analysis of the 2017 and 2018 annual reports of the National Centre for Vector Borne Disease Control (NCVBDC). Results: The district of Kolkata had a high Annual Parasite Incidence (API) of Malaria of 3.72 during 2017 which decreased to 3.12 in 2018. Conclusion: If interventions such as the treatment of asymptomatic carriers take place, it is expected that the API will come down sooner in Kolkata district and in the rest of the state too.
背景:疟疾仍然发生在印度东部的一个邦——西孟加拉邦。材料和方法:研究设计包括对国家媒介传播疾病控制中心(NCVBDC) 2017年和2018年年度报告的分析。结果:加尔各答地区疟疾寄生虫年发病率(API)较高,2017年为3.72,2018年降至3.12。结论:如果采取诸如治疗无症状携带者等干预措施,预计加尔各答地区和该邦其他地区的API将更快下降。
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引用次数: 0
Abdominal pain in Langya henipavirus and severity of infection: A report 狼牙亨尼帕病毒引起的腹痛与感染严重程度:一份报告
Pub Date : 2023-01-01 DOI: 10.4103/ajoim.ajoim_16_22
P. Sookaromdee, V. Wiwanitkit
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引用次数: 0
A cross-sectional study of lipid profile in anemic patients in a tertiary care center 三级保健中心贫血患者血脂剖面的横断面研究
Pub Date : 2023-01-01 DOI: 10.4103/ajoim.ajoim_4_23
Sruthisri Beeravelli, Nagarajan Kinathankaraiyan, Rajendran Manickam
Background: Various studies have reported a correlation (both positive and negative) between the status of anemia and lipid profile. Studies observed that the lipoproteins levels were significantly lower in anemic patients, and this reduction was proportional to the severity of anemia and not related to the type of anemia. Objectives: To study the lipid profile among the anemia patients and the correlation between the severity of the anemia and lipid subfractions. Materials and Methods: This is a cross-sectional study among 85 subjects with anemia in a Tertiary care hospital, who satisfied the eligibility criteria. After detailed history, clinical examination and blood investigations including blood counts, hemoglobin, and lipid profile were done. Results: The mean hemoglobin (g/dL) among the subjects was 7.86 (±2.03) g/dL ranging from 3 to 11 g/dL. Among the 85 subjects, 35 (41.18%) had dimorphic anemia followed by 21 (24.71%) had microcytic hypochromic anemia, 15 (17.65%) had normocytic hypochromic anemia, and 14 subjects (16.47%) had normocytic normochromic anemia. Body mass index was not significantly associated with the type and severity of anemia. Lipid subfractions were not associated with the type of anemia and significantly decreased with an increase in the severity of anemia. Conclusion: The lipid profile parameters in our study were not associated with type of anemia and significantly decreased with an increase in the severity of anemia.
背景:各种研究已经报道了贫血状态和血脂之间的相关性(包括正相关性和负相关性)。研究发现,贫血患者的脂蛋白水平明显降低,这种降低与贫血的严重程度成正比,而与贫血的类型无关。目的:研究贫血患者血脂状况及贫血严重程度与血脂亚组分的关系。材料和方法:这是一项横断面研究,纳入三级医院85例贫血患者,符合入选标准。经过详细的病史、临床检查和血液调查,包括血细胞计数、血红蛋白和血脂。结果:受试者平均血红蛋白(g/dL)为7.86(±2.03)g/dL,范围为3 ~ 11 g/dL。85例患者中,二形型贫血35例(41.18%),小细胞型低色性贫血21例(24.71%),正型型低色性贫血15例(17.65%),正型型贫血14例(16.47%)。体重指数与贫血的类型和严重程度无显著相关性。脂质亚组分与贫血类型无关,并随着贫血严重程度的增加而显著降低。结论:本研究中血脂参数与贫血类型无关,且随着贫血严重程度的增加而显著降低。
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引用次数: 0
Snakebite in North East India 印度东北部被蛇咬伤
Pub Date : 2023-01-01 DOI: 10.4103/2278-8239.378214
S. Baruah, A. Dutta
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引用次数: 0
Antibody response to SARS-CoV-2-infected healthcare workers during first wave of Covid-19 pandemic in a tertiary care center of Assam 阿萨姆邦三级医疗中心在第一波Covid-19大流行期间对sars - cov -2感染医护人员的抗体反应
Pub Date : 2022-07-01 DOI: 10.4103/ajoim.ajoim_10_22
G. Gogoi, M. Medhi, R. Nath, U. Dutta, M. Borgohain, Binod Gohain, N. Bhattacharyya, M. Hussain
Context: Healthcare workers (HCWs) were at the front line of the COVID-19 (corona virus disease-19) pandemic management and were at higher risks of contracting SARS-CoV-2 due to occupational exposure. The objectives of the present study were to estimate the antibody response to SARS-CoV-2 among COVID-19-positive HCWs and its persistence in subsequent follow-up samples and to compare antibody response between rapid antigen/real time polymerase chain reaction (RT-PCR) groups. Settings and Designs: This hospital-based cross-sectional study was carried out in Assam Medical College. Materials and Methods: Inclusion criteria were SARS-CoV-2 test, which was confirmed in HCWs. A total of 127 HCWs were included. The samples were tested for SARS-CoV-2 IgG by qualitative indirect ELISA using InBios SCoV-2 DetectTM IgG kit. First sample was collected from 25th day to 35th day of SARS-CoV-2. First and second follow-up samples were collected in 3 and 6 months, respectively. Statistical Analysis Used: Epi Info version 7 was used. The χ2 test was done. Results: A total of 69% male and 31% female HCWs were included. Most of them were in the 20–29 years age group (48%). About 92% were symptomatic and 20% had comorbidities. Overall seroconversion was 88% (RAT category 98.61% and RT-PCR 74.55%). Symptomatic category showed 90.68% seropositivity. The follow-up at the 3rd and 6th month showed 93.85% and 88.24% seropositivity, respectively. Conclusion: Rapid antigen test-positive symptomatic people have more chances of development of antibodies within a period of 1 month and sustained for more than 6 months in their blood.
背景:卫生保健工作者(HCWs)处于COVID-19(冠状病毒病-19)大流行管理的第一线,由于职业暴露,感染SARS-CoV-2的风险较高。本研究的目的是评估covid -19阳性医护人员对SARS-CoV-2的抗体反应及其在后续随访样本中的持久性,并比较快速抗原/实时聚合酶链反应(RT-PCR)组之间的抗体反应。环境和设计:这项以医院为基础的横断面研究在阿萨姆邦医学院进行。材料和方法:纳入标准为SARS-CoV-2检测,经卫生保健工作者确认。共包括127名医护人员。采用InBios SCoV-2 DetectTM IgG试剂盒,采用定性间接ELISA法检测SARS-CoV-2 IgG。第一次采集时间为SARS-CoV-2感染第25天至第35天。第一次和第二次随访分别于3个月和6个月采集样本。使用统计分析:使用Epi Info version 7。采用χ2检验。结果:共纳入了69%的男性和31%的女性卫生保健员。其中大多数在20-29岁年龄组(48%)。约92%有症状,20%有合并症。总血清转化率为88% (RAT分类为98.61%,RT-PCR为74.55%)。症状型血清阳性率为90.68%。随访第3、6个月血清阳性率分别为93.85%和88.24%。结论:快速抗原检测阳性症状者在1个月内出现抗体的机会较多,且抗体在其血液中持续6个月以上。
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引用次数: 0
“BABOON” syndrome: A case report “狒狒”综合征1例报告
Pub Date : 2022-07-01 DOI: 10.4103/ajoim.ajoim_14_22
Dipankar Das, A. Dutta, Bidisha Dangoria, Chetan Damani, Imdadul Hussain
Symmetrical drug-related intertriginous and flexural exanthema (SDRIFE), previously known as Baboon syndrome, is a symmetrical erythematous rash on the gluteal and intertriginous areas observed after exposure to systemic drugs. This was the case of a 35-year-old woman who presented to medicine OPD (outpatient department) of Assam Medical College and Hospital (AMCH), Dibrugarh with a history of a macular rash over the right and left armpit and right upper back, buttocks and inner aspect of the left thigh.
对称性药物相关性三叉肌和弯曲性皮疹(SDRIFE),以前称为狒狒综合征,是在全身药物暴露后观察到的臀肌和三叉肌区域的对称红斑皮疹。这是一名35岁妇女的病例,她到Dibrugarh的阿萨姆邦医学院和医院(AMCH)的内科OPD(门诊部)就诊,她有左右腋窝和右上背部、臀部和左大腿内侧的黄斑皮疹病史。
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引用次数: 0
Referencing in scientific writing and research 科学写作和研究中的参考文献
Pub Date : 2022-07-01 DOI: 10.4103/ajoim.ajoim_6_22
S. Shrivastava, P. Shrivastava
In general, research activities are essential, but it is equally important to ensure that the research findings are shared with different researchers across the world. In simple terms, referencing refers to giving credit to the intellectual work of a person/s or the source of information. Referencing is a strategy that tends to provide support to the statements made by the researchers in their own work. It is one of the most effective strategies to reduce the incidence of plagiarism, as it gives an opportunity for the authors to let the readers know about the ideas which are theirs and those which are contributions of other researchers. To conclude, referencing is an important aspect of the research writing and has been linked with multiple benefits to the authors, readers, and other researchers. Thus, it is our responsibility to envisage citation of appropriate references in the research work, so that more people become aware of the similar kind of works and replicate them in their individual settings.
一般来说,研究活动是必不可少的,但确保研究成果与世界各地不同的研究人员共享同样重要。简单来说,引用指的是对某人的智力工作或信息来源给予肯定。参考文献是一种倾向于为研究人员在自己的工作中所作的陈述提供支持的策略。这是减少剽窃发生率的最有效策略之一,因为它给了作者一个机会让读者知道哪些是他们的想法,哪些是其他研究人员的贡献。综上所述,参考文献是研究写作的一个重要方面,对作者、读者和其他研究人员都有多重好处。因此,设想在研究工作中引用适当的参考文献是我们的责任,这样更多的人就会意识到类似的作品,并在他们的个人环境中复制它们。
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引用次数: 0
COVID Immunity COVID免疫力
Pub Date : 2022-07-01 DOI: 10.4103/2278-8239.361831
B. Hazarika
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引用次数: 0
Clinico-etiological profile of lower respiratory tract infections in HIV-positive patients hiv阳性患者下呼吸道感染的临床病因学分析
Pub Date : 2022-07-01 DOI: 10.4103/ajoim.ajoim_8_22
Darpan Rajkhowa, B. Kalita, M. Sai
Background: The type of pathogens responsible for opportunistic infections in human immunodeficiency virus (HIV)-infected persons varies from region to region. Till date, very few studies covering respiratory tract infections in HIV-positive patients have been conducted in this part of the country. This study was conducted in order to get better understanding of the clinical picture of lower respiratory tract infections (LRTIs) in HIV-positive patients in this region. Aim: The aim was to study the LRTIs in HIV-positive patients. Settings and Design: Eighty-one patients were diagnosed as HIV-positive with LRTIs, attending to Department of Medicine at Assam Medical College and Hospital, Dibrugarh, Assam, India. Materials and Methods: Personal and family history was collected with emphasis on the duration of HIV-positive status, any chronic illness, sexually transmitted diseases, history of blood transfusions, or any surgical procedures. A detailed general and systemic examination was done. Statistical Analysis Used: The data collected were tabulated in MS Excel and analyzed using SPSS 20.0. The categorical variables were summarized as frequency and percentages. Results: Mycobacterium tuberculosis was responsible for 18.52% of cases of LRTIs, whereas fungal etiology was found in 7.41% of the cases. The most common bacterial and fungal pathogens isolated were Streptococcus pneumoniae (23.46%) and Candida albicans (7.41%), respectively. Conclusion: Low CD4 cell count is an important indicator for the risk of pulmonary tuberculosis and fungal LRTIs, as shown in our study. Periodic CD cell count in HIV-positive patients is important in this regard.
背景:导致人类免疫缺陷病毒(HIV)感染者机会性感染的病原体类型因地区而异。迄今为止,在该国这一地区进行的涉及艾滋病毒阳性患者呼吸道感染的研究很少。本研究是为了更好地了解该地区hiv阳性患者下呼吸道感染(LRTIs)的临床情况。目的:研究hiv阳性患者的LRTIs。环境和设计:81名被诊断为hiv阳性的下呼吸道感染患者,在印度阿萨姆邦迪布鲁加尔的阿萨姆邦医学院和医院医学部就诊。材料和方法:收集个人和家族史,重点收集hiv阳性状态持续时间、任何慢性疾病、性传播疾病、输血史或任何外科手术史。做了详细的全身检查和系统检查。统计分析方法:收集的数据在MS Excel中制表,使用SPSS 20.0进行分析。分类变量总结为频率和百分比。结果:下呼吸道感染病例中结核分枝杆菌占18.52%,真菌占7.41%。检出的细菌和真菌病原体分别为肺炎链球菌(23.46%)和白色念珠菌(7.41%)。结论:CD4细胞计数低是判断肺结核和真菌性下呼吸道感染风险的重要指标。在这方面,hiv阳性患者的定期CD细胞计数很重要。
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引用次数: 0
CO-RABS score: A novel bedside scale to predict the severity in COVID patients CO-RABS评分:一种预测COVID患者严重程度的新型床边量表
Pub Date : 2022-07-01 DOI: 10.4103/ajoim.ajoim_9_22
Merugolu Finny Theo Joseph, Dabboo Patwari, Kishore Kumar Talukdar, B. Neog, Sunny Yadav, Nasim Riaz
Study Objective: To determine the prognostic significance of a new score (CO-RABS), formulated by our Institute to classify the covid patients into mild, moderate, severe cases and also to compare it with the conversion AIIMS based classification. Patients and Methods: This is a retrospective study in which we have collected data from the medical records of patients who were admitted in our Hospital with covid infection during 2nd and 3rd waves of the pandemic. We have taken Comorbidities (CO), Respiratory rate (R), Age (A), Blood pressure (B) and SpO2 (S) of the patients at the time of admission to calculate an overall score (Abbreviated as CO-RABS). Basing on this score, the patients were classified into mild, moderate and severe cases. We then compared our CO-RABS score based classification with AIIMS classification using a statistical software. Results: We studied 727 patients (440 men, 287 women) and 99 patients died due to covid related complications. The ability to predict the prognosis was higher for our newly formulated CO-RABS score when compared to AIIMS classification. (AUC of CO-RABS 0.88 vs 0.82 of AIIMS; p < 0.05). Conclusion: The ability of CO-RABS score to predict the prognosis of covid infection is higher than that of AIIMS/ICMR classification. Hence it can be used as a supportive tool in the covid management protocol along with all the other conversion modes of treatment.
研究目的:探讨我院制定的将新冠肺炎患者分为轻、中、重度的CO-RABS评分方法的预后意义,并与基于AIIMS的转换评分方法进行比较。患者和方法:这是一项回顾性研究,我们从大流行第二波和第三波期间入院的covid感染患者的医疗记录中收集数据。取患者入院时的合并症(CO)、呼吸率(R)、年龄(A)、血压(B)、SpO2 (S),计算总评分(简称CO- rabs)。根据该评分将患者分为轻、中、重度。然后使用统计软件将基于CO-RABS评分的分类与AIIMS分类进行比较。结果:我们研究了727例患者(男性440例,女性287例),99例患者死于与covid相关的并发症。与AIIMS分类相比,我们新制定的CO-RABS评分预测预后的能力更高。(CO-RABS的AUC为0.88,AIIMS为0.82;P < 0.05)。结论:CO-RABS评分对covid感染预后的预测能力高于AIIMS/ICMR分级。因此,它可以作为covid管理协议中的辅助工具,与所有其他转换治疗模式一起使用。
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引用次数: 0
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Assam Journal of Internal Medicine
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