E. N. Sivtseva, S. S. Shadrina, T. K. Davydova, S. Sivtsev, V. Melnikov, I.A. Kirensky
{"title":"The content of the main chemical elements in the blood serum of present-day Evenks, the indigenous ethnic group of the Russian Arctic","authors":"E. N. Sivtseva, S. S. Shadrina, T. K. Davydova, S. Sivtsev, V. Melnikov, I.A. Kirensky","doi":"10.25789/ymj.2023.81.23","DOIUrl":"https://doi.org/10.25789/ymj.2023.81.23","url":null,"abstract":"","PeriodicalId":42701,"journal":{"name":"Yakut Medical Journal","volume":"4 1","pages":""},"PeriodicalIF":0.1,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84251125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L. Afanasyeva, A. Alekhnovich, A. Kalininskaya, A. V. Lazarev, M. Kizeev
In the Republic of Sakha (Yakutia) for the period 2015-2020, an increase in mortality and a decrease in fertility were noted, higher rates of primary morbidity were noted, including in the class of respiratory diseases, 1.4 times higher than in the Russian Federation, while the incidence rate of COVID-19 was higher;higher incidence of digestive diseases was noted (1.7 three times higher than in the Russian Federation). Indicators of primary morbidity of children and adolescents are higher than the total population in almost all classes of diseases for all 6 years of analysis (2015-2020). Differences in the indicators of primary morbidity in the uluses of the Republic of Sakha (Yakutia) by 3.3 times, which are associated with different availability of medical care in different areas of residence. The information obtained is important for the development of management decisions at the regional level.
{"title":"Medical and demographic situation in the Republic of Sakha (Yakutia)","authors":"L. Afanasyeva, A. Alekhnovich, A. Kalininskaya, A. V. Lazarev, M. Kizeev","doi":"10.25789/ymj.2023.81.13","DOIUrl":"https://doi.org/10.25789/ymj.2023.81.13","url":null,"abstract":"In the Republic of Sakha (Yakutia) for the period 2015-2020, an increase in mortality and a decrease in fertility were noted, higher rates of primary morbidity were noted, including in the class of respiratory diseases, 1.4 times higher than in the Russian Federation, while the incidence rate of COVID-19 was higher;higher incidence of digestive diseases was noted (1.7 three times higher than in the Russian Federation). Indicators of primary morbidity of children and adolescents are higher than the total population in almost all classes of diseases for all 6 years of analysis (2015-2020). Differences in the indicators of primary morbidity in the uluses of the Republic of Sakha (Yakutia) by 3.3 times, which are associated with different availability of medical care in different areas of residence. The information obtained is important for the development of management decisions at the regional level.","PeriodicalId":42701,"journal":{"name":"Yakut Medical Journal","volume":"25 1","pages":""},"PeriodicalIF":0.1,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79219866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E. Zasimova, A. Golderova, E. D. Okhlopkova, E.P. Kudrin, A.I. Yugova, N. A. Dmitriev
{"title":"Biochemical parameters of blood in the mass-wrestlers during the training period","authors":"E. Zasimova, A. Golderova, E. D. Okhlopkova, E.P. Kudrin, A.I. Yugova, N. A. Dmitriev","doi":"10.25789/ymj.2023.81.29","DOIUrl":"https://doi.org/10.25789/ymj.2023.81.29","url":null,"abstract":"","PeriodicalId":42701,"journal":{"name":"Yakut Medical Journal","volume":"11 1","pages":""},"PeriodicalIF":0.1,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87247589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
N. V. Zaitseva, M. Zemlyanova, Yu. V. Koldibekova, E. V. Peskova, N. Bulatova
{"title":"Protein markers of negative effects in children under the influence of natural cold","authors":"N. V. Zaitseva, M. Zemlyanova, Yu. V. Koldibekova, E. V. Peskova, N. Bulatova","doi":"10.25789/ymj.2023.81.21","DOIUrl":"https://doi.org/10.25789/ymj.2023.81.21","url":null,"abstract":"","PeriodicalId":42701,"journal":{"name":"Yakut Medical Journal","volume":"84 1","pages":""},"PeriodicalIF":0.1,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84305296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effects of intraoperative use of beta-adrenoblockers in endoscopic rhinosinus surgery under general anesthesia","authors":"V. Pavlov, L. Kolotilov, S. Karpishchenko","doi":"10.25789/ymj.2023.81.09","DOIUrl":"https://doi.org/10.25789/ymj.2023.81.09","url":null,"abstract":"","PeriodicalId":42701,"journal":{"name":"Yakut Medical Journal","volume":"12 1","pages":""},"PeriodicalIF":0.1,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84397330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E. Suprun, S. Suprun, N. Kuderova, G. Evseeva, O. Lebedko
{"title":"Assessment of vitamin D level as a factor of bronchial asthma control in children of the Amur region","authors":"E. Suprun, S. Suprun, N. Kuderova, G. Evseeva, O. Lebedko","doi":"10.25789/ymj.2023.81.03","DOIUrl":"https://doi.org/10.25789/ymj.2023.81.03","url":null,"abstract":"","PeriodicalId":42701,"journal":{"name":"Yakut Medical Journal","volume":"92 1","pages":""},"PeriodicalIF":0.1,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79608573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
We hypothesize that cognitive impairment in humans after COVID-19 is due to a change in the epigenetic regulation of brain neurons due to the activation of retroelements under the influence of SARS-CoV-2 virus. In order to confirm the role of transposons in changing the functioning of the brain in patients with COVID-19, the scientific literature and the results of meta-analyses over the past 3 years were studied. As a result, we found that SARS-CoV-2 affects the brain not only through its direct effect, induction of inflammation and coagulopathy, but also through the activation of retroelements, the transcripts of which are processed into microRNAs. This is reflected in changes in the epigenetic regulation of genes in brain neurons, which is reflected in cognitive functions. The mechanisms of integration of the cDNA of SARS-CoV-2 virus into the human genome with the help of retroelement enzymes are described, which is reflected in the development of long-term changes in cognitive functions after COVID-19.
{"title":"Impact of COVID-19 on Gognitive change","authors":"R. Mustafin, A. Kazantseva, E. Khusnutdinova","doi":"10.25789/ymj.2023.81.25","DOIUrl":"https://doi.org/10.25789/ymj.2023.81.25","url":null,"abstract":"We hypothesize that cognitive impairment in humans after COVID-19 is due to a change in the epigenetic regulation of brain neurons due to the activation of retroelements under the influence of SARS-CoV-2 virus. In order to confirm the role of transposons in changing the functioning of the brain in patients with COVID-19, the scientific literature and the results of meta-analyses over the past 3 years were studied. As a result, we found that SARS-CoV-2 affects the brain not only through its direct effect, induction of inflammation and coagulopathy, but also through the activation of retroelements, the transcripts of which are processed into microRNAs. This is reflected in changes in the epigenetic regulation of genes in brain neurons, which is reflected in cognitive functions. The mechanisms of integration of the cDNA of SARS-CoV-2 virus into the human genome with the help of retroelement enzymes are described, which is reflected in the development of long-term changes in cognitive functions after COVID-19.","PeriodicalId":42701,"journal":{"name":"Yakut Medical Journal","volume":"41 1","pages":""},"PeriodicalIF":0.1,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85439301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G. R. Allayarova, T. K. Larionova, R. Daukaev, E. E. Zelenkovskaya, S. R. Afonkina, E. Aukhadieva, D. E. Musabirov
{"title":"Features of the elemental composition of the hair of children living in areas with different anthropogenic load","authors":"G. R. Allayarova, T. K. Larionova, R. Daukaev, E. E. Zelenkovskaya, S. R. Afonkina, E. Aukhadieva, D. E. Musabirov","doi":"10.25789/ymj.2023.81.15","DOIUrl":"https://doi.org/10.25789/ymj.2023.81.15","url":null,"abstract":"","PeriodicalId":42701,"journal":{"name":"Yakut Medical Journal","volume":"54 1","pages":""},"PeriodicalIF":0.1,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81388735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Transanal endoscopic resection of rectal neoplasms","authors":"A. Ilkanich, Y. Voronin, F. Aliev","doi":"10.25789/ymj.2023.81.11","DOIUrl":"https://doi.org/10.25789/ymj.2023.81.11","url":null,"abstract":"","PeriodicalId":42701,"journal":{"name":"Yakut Medical Journal","volume":"12 1","pages":""},"PeriodicalIF":0.1,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84223607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Parshina, E. Moskaleva, A. Petrova, L. V. Rychkova, O. Ogarkov, E. Orlova, A. Vanyarkina, E. Novikova, E. D. Kazantseva
The article presents the results of investigation of SARS-CoV-2 viral load in newborns with RT-PCR confirmed COVID-19 of different severity. It has been revealed that total amount of SARS-CoV-2 RNA on nasopharyngeal mucosa of newborns is significantly higher as compared to elder children and is not associated with disease severity and lung injury.
{"title":"SARS-CoV-2 VIRAL LOAD IN NEWBORNS WITH COVID-19","authors":"A. Parshina, E. Moskaleva, A. Petrova, L. V. Rychkova, O. Ogarkov, E. Orlova, A. Vanyarkina, E. Novikova, E. D. Kazantseva","doi":"10.25789/ymj.2023.81.16","DOIUrl":"https://doi.org/10.25789/ymj.2023.81.16","url":null,"abstract":"The article presents the results of investigation of SARS-CoV-2 viral load in newborns with RT-PCR confirmed COVID-19 of different severity. It has been revealed that total amount of SARS-CoV-2 RNA on nasopharyngeal mucosa of newborns is significantly higher as compared to elder children and is not associated with disease severity and lung injury.","PeriodicalId":42701,"journal":{"name":"Yakut Medical Journal","volume":"14 1","pages":""},"PeriodicalIF":0.1,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84963572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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