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Relationship between motor proficiency and blood pressure: the role of mediated by nutritional status 运动熟练度与血压的关系:营养状况的中介作用
IF 0.2 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2022-10-21 DOI: 10.4025/actascihealthsci.v45i1.59093
Pâmela Norraila da Silva, J. L. Vieira, Francielle Ferreira da Rocha, Francielli Cheuczuk, Luciana Ferreira
Motor skills during childhood are extremely important for having an active lifestyle in adulthood; however, with the technological advance several plays and even the family environment have undergone changes, which affected the lifestyle adopted by the population. The present study aimed at investigating motor proficiency and blood pressure, as well as assessing the mediating role of nutritional status in such a correlation. This is a cross-sectional study carried out with 374 children aged 7 to 10 from the city of Maringá-PR. The nutritional status was measured by using the Body Mass Index (BMI) according to age and sex. The Bruininks-Oseretsky Test of Motor Proficiency, Second Edition, (BOT-2), was used to evaluate motor proficiency; the blood pressure was measured by using the Omron Deluxe HEM-7200® digital meter. The results showed a negative correlation between motor proficiency and body mass index and systolic and diastolic blood pressure. The analysis of structural equations revealed that there was no statistically significant direct impact of motor proficiency on blood pressure. However, when the mediation of nutritional status was included, a significant negative correlation between motor proficiency and nutritional status was seen, but positive in relation to systolic and diastolic blood pressure. In conclusion, motor proficiency has no direct influence on blood pressure; however, when mediated by nutritional status, the effect becomes significant. It is worth mentioning that the lower the motor proficiency and the higher the body mass, the higher the systolic and diastolic blood pressure was.
儿童时期的运动技能对成年后积极的生活方式极为重要;然而,随着科技的进步,一些戏剧甚至家庭环境都发生了变化,这影响了人们的生活方式。本研究旨在调查运动熟练程度和血压,并评估营养状况在这种相关性中的中介作用。这是一项横断面研究调查了374名7到10岁的儿童来自Maringá-PR市。根据年龄和性别,采用身体质量指数(BMI)测定营养状况。采用Bruininks-Oseretsky运动能力测验(BOT-2)评估运动能力;使用欧姆龙豪华HEM-7200®数字血压计测量血压。结果显示运动熟练程度与体重指数、收缩压和舒张压呈负相关。结构方程分析显示,运动熟练程度对血压没有统计学上显著的直接影响。然而,当包括营养状况的中介时,运动熟练程度与营养状况之间存在显著的负相关,但与收缩压和舒张压呈正相关。总之,运动熟练程度对血压无直接影响;然而,当营养状况介导时,效果变得显著。值得一提的是,运动熟练程度越低,体重越高,收缩压和舒张压越高。
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引用次数: 0
Cultural adaptation of the opening minds scale for health care providers(OMS-HC) for Brazil 巴西卫生保健提供者开放思想量表(OMS-HC)的文化适应
IF 0.2 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2022-10-21 DOI: 10.4025/actascihealthsci.v45i1.54524
Bruna Sordi Carrara, C. Ventura, Simone de Godoy Costa
The Opening Minds Scale for Health Care Providers (OMS-HC) identifies health professionals' attitudes and behaviors towards people with mental illness. The aim of this study was to culturally adapt the OMS-HC for use in Brazil through the description of the translation and back-translation process, face and content validity assessment, and reliability assessment. The cultural adaptation occurred through translation of the original instrument, assessment, and synthesis of the translation by the Committee of Judges, back-translation, and pre-test. The cultural adaptation occurred without significant intercurrences, the changes resulting from the translations and assessments were, in general, specific and related to the changes of certain words by other synonyms for better adaptation. Cronbach's alpha was 0.74. The Brazilian version of the OMS-HC presented language adequate to the Brazilian context that is easy to apply, with adequate format for use, appropriate understanding, and consistency in relation to the original version. The Brazilian version of the OMS-HC is suitable for the development of a study to assess its psychometric properties.
卫生保健提供者开放思想量表(OMS-HC)确定卫生专业人员对精神疾病患者的态度和行为。本研究的目的是通过对翻译和反翻译过程的描述、面部和内容效度评估以及信度评估来适应OMS-HC在巴西的使用。文化适应是通过对原文书的翻译、评审委员会对译文的评估和综合、反译和预试来实现的。文化适应过程中没有明显的相互影响,翻译和评价所产生的变化一般来说是具体的,与其他同义词对某些词的改变有关,以更好地适应。Cronbach’s alpha为0.74。OMS-HC的巴西版本提供了适合巴西上下文的语言,易于应用,具有适当的使用格式,适当的理解和与原始版本的一致性。巴西版的OMS-HC适合用于评估其心理测量特性的研究。
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引用次数: 1
Association between chronic pain, depression, somatization and temporomandibular disorders in a southern brazilian population 巴西南部人群慢性疼痛、抑郁、躯体化和颞下颌疾病之间的关系
IF 0.2 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2022-10-21 DOI: 10.4025/actascihealthsci.v45i1.59474
T. Silva, R. S. Salbego, Rachel Seeger Ilha, Thais Fernanda Hahn Dutra, Fernanda Tomazoni, Vitória de Oliveira Chami, Luíza Pereira do Nascimento, M. Marquezan
Introduction: Temporomandibular disorder (TMD) is defined as a set of pathological clinical conditions involving the masticatory muscles, the temporomandibular joint, or both, and the associated structures. It is often associated with chronic headaches, cervical pain, otologic symptoms and may be accompanied by some degree of physical or psychological disability in patients. Objective: To investigate the association of chronic pain-related disability, depression, and somatization with temporomandibular disorders. Methods: It was a transversal study with 275 patients evaluated using the RDC/TMD (Research Diagnostic Criteria for Temporomandibular Disorders). The variables of Axis I (myofascial pain, disc displacement and other joint conditions) and Axis II (chronic pain-related disability, depression and somatization) were crossed using Fischer’s Exact Test (p <0.05). Results: Statistically significant association was found among factors of chronic pain-related disability, depression and somatization with myofascial pain diagnosis (p =0.000, p =0.001, p =0.000, respectively), as well as joint conditions (arthralgia, osteoarthritis and osteoarthrosis) (p =0.000, p =0.008, p =0.003, respectively). Conclusion: There is a positive association between chronic pain, depression and somatization (Axis II variables) with and myofascial pain and other joint conditions (Axis I). Disc displacements were not associated to variables of Axis II.
颞下颌关节紊乱(Temporomandibular disorder, TMD)是一组涉及咀嚼肌、颞下颌关节或两者及相关结构的病理临床状况。它通常与慢性头痛、颈椎疼痛、耳科症状有关,并可能伴有患者某种程度的身体或心理残疾。目的:探讨慢性疼痛相关残疾、抑郁和躯体化与颞下颌疾病的关系。方法:采用RDC/TMD(颞下颌疾病研究诊断标准)对275例患者进行横向研究。轴I变量(肌筋膜疼痛、椎间盘移位等关节状况)和轴II变量(慢性疼痛相关残疾、抑郁和躯体化)采用Fischer精确检验交叉(p <0.05)。结果:慢性疼痛相关残疾、抑郁、躯体化等因素与肌筋膜疼痛诊断(p =0.000, p =0.001, p =0.000)及关节状况(关节痛、骨关节炎、骨关节病)(p =0.000, p =0.008, p =0.003)有统计学意义。结论:慢性疼痛、抑郁和躯体化(轴II变量)与肌筋膜疼痛和其他关节状况(轴I变量)呈正相关。椎间盘移位与轴II变量无关。
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引用次数: 0
Presence of autoantibodies and epidemiological characteristics of systemic sclerosis patients in western Paraná 西部地区系统性硬化症患者自身抗体的存在与流行病学特征
IF 0.2 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2022-10-21 DOI: 10.4025/actascihealthsci.v45i1.59350
Alana Rubia Balbinot, Vanuza Hoinatz, Leticia de Abreu Wiedmer de Siqueira, A. Adame, Poliana Vieira da Silva Menolli, R. A. Menolli
Systemic sclerosis (SSc) is a systemic autoimmune disease of the connective tissue with unknown etiology, characterized by abnormal collagen deposition in the skin. The changes in patients result in the obliteration of microvessels and fibrosis, leading to damage to the skin, gastrointestinal tract, kidneys, lungs, heart, and oral cavity. Brazil has insufficient data about the epidemiological and laboratory aspects of SSc. This study aimed to identify and characterize the patients in treatment for SSc in Cascavel/PR, a city in the south of Brazil. Data were collected from March 2019 to September 2020 from all health services of Cascavel that provide care in rheumatology: a university-affiliated hospital, two public outpatient clinics, and six private clinics. Data about age, sex, residence, time to diagnosis, the form of the disease, and the results of tests for antinuclear (ANA) and anti-extractable nuclear antigens (ENA) antibodies were obtained. The study identified 57 patients; 82.5% were female with a mean age of 50.4 years, and the predominant disease form was diffuse (52.6%). The ANA test was positive in 87.7% of the patients, of which 49.2% showed high titers and a predominance of the centromeric pattern. Anti-Scl-70, anti-centromere (ACA), and anti-RNA polymerase III antibodies were positive in 28.1%, 25%, and 5% of the patients. The characteristics of the patients diagnosed with SSc in Cascavel/PR are similar to those reported in the literature. This study contributed to the scarce Brazilian data about the disease.
系统性硬化症(SSc)是一种病因不明的结缔组织系统性自身免疫性疾病,以皮肤中异常胶原沉积为特征。患者的变化导致微血管闭塞和纤维化,导致皮肤、胃肠道、肾脏、肺、心脏和口腔受损。巴西关于南南血吸虫的流行病学和实验室方面的数据不足。本研究旨在识别和表征巴西南部城市Cascavel/PR的SSc治疗患者。数据收集于2019年3月至2020年9月,来自卡斯卡维尔提供风湿病护理的所有卫生服务机构:一所大学附属医院、两家公立门诊诊所和六家私人诊所。获得年龄、性别、居住地、诊断时间、疾病形式以及抗核(ANA)和抗可提取核抗原(ENA)抗体检测结果等数据。该研究确定了57名患者;82.5%为女性,平均年龄50.4岁,以弥漫性疾病为主(52.6%)。在87.7%的患者中,ANA检测呈阳性,其中49.2%呈高滴度,以着丝粒型为主。抗scl -70、抗着丝粒(ACA)和抗rna聚合酶III抗体分别在28.1%、25%和5%的患者中呈阳性。Cascavel/PR中诊断为SSc的患者的特征与文献报道相似。这项研究弥补了巴西关于该疾病的稀缺数据。
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引用次数: 0
Evaluation of oral hygiene behaviors and teeth condition of students in oral and dental health nursing course 口腔与牙齿保健护理课程学生口腔卫生行为与牙齿状况的评价
IF 0.2 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2022-10-21 DOI: 10.4025/actascihealthsci.v45i1.59561
Mehtap Sönmez, Mine Akben, Berna Göçebe
Nursing students are role model related to health franchise play an important in oral health care and promotion. This study aim is assessment the caries and oral and dental health behaviors of nurse students who be able expected take upon the responsibility of oral health in future. This was descriptive observational study with cross‑sectional approach, conducted at a state university in Mediterranean, Turkey. The study population was formed from 34 nursing students who voluntary select to course of oral and dental health nursing. Firstly, data were collected by socio-demographic form and then all students had been examined by dentist researcher. It was determined that 76.5% of the nursing students included in the study had at least one tooth decay, 70.6% needed treatment, and 67.6% had debris. It was determined that there was a relationship between gender, floss use, mouthwash, regular brushing teeth twice a day before the age of 6, smoking, and D, F, M, DMFS, DMFT indices in those who were breastfed for >=6 months. Increasing the awareness level of students will have a positive impact on the health of the patients they will care for. 
护理专业学生是与健康特许经营相关的楷模,在口腔健康护理和推广中发挥着重要作用。本研究旨在评估未来能承担口腔健康责任的护生的龋病及口腔及牙齿健康行为。这是一项描述性观察性研究,采用横断面方法,在土耳其地中海的一所州立大学进行。研究对象为34名自愿选择口腔与牙齿保健护理专业的护生。首先通过社会人口统计形式收集数据,然后由牙医研究员对所有学生进行检查。76.5%的护生至少有一颗蛀牙,70.6%的护生需要治疗,67.6%的护生有牙屑。测定6个月以上母乳喂养儿童的性别、牙线使用情况、漱口水、6岁前每天定期刷牙2次、吸烟与D、F、M、DMFS、DMFT指数存在相关性。提高学生的意识水平将对他们将要照顾的病人的健康产生积极的影响。
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引用次数: 1
Does Clonazepam induce salivary gland toxicity? A morphometric analysis of salivary glands in pregnant mice 氯硝西泮会引起唾液腺毒性吗?孕鼠唾液腺形态计量学分析
IF 0.2 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2022-10-21 DOI: 10.4025/actascihealthsci.v45i1.60003
Adrielle Larissa D'Andrea, Márjori Frítola, C. C. D. Barros, Isabella Grippe da Silva Pinhatari, C. C. N. Martins, Camila Salvador Sestario, M. J. S. Salles
Physiological alterations in pregnancy may induce changes in salivary secretion and a predisposition to anxiety disorders. Clonazepam, a benzodiazepine, is recommended as the first choice for the treatment of anxiety disorders. To date, no studies have described the consequences of using this drug on the salivary glands of pregnant women. Therefore, the objective was to evaluate the alterations induced by exposure to Clonazepam in the salivary glands of pregnant mice. Twenty-two pregnant Swiss mice were divided into a control group (C) and a treated group (T), which received distilled water and 10 mg Kg-1 of Clonazepam, respectively, via gavage, daily, from the 5 to the 17th day of pregnancy. On the 18th day, euthanasia and collection of salivary glands were carried out, and the salivary glands were histologically processed and morphometrically analyzed under an optical microscope. The area, perimeter, and diameter of the acini and the thickness of the secretory ducts of each gland were measured. Parametric data (expressed as mean and standard deviation) were analyzed using the Student's t-test, and non-parametric data (expressed as median and interquartile range) using the Mann-Whitney test (p <0.05). Parotid glands’ acinar diameters (C: 44.1 ± 12.2 µm; T: 36.5 ± 7.8 µm; p =0.002) and ductal thicknesses (C: 16.9 [14.3-21.3] µm; T: 15.1 [13.4-16.3] µm; p =0.043) were statistically smaller in the T group than in the C group. No further alterations were found in other parameters from parotid glands, nor in submandibular and sublingual glands. It is concluded that Clonazepam induces morphological alterations in the parotid glands of pregnant mice. These alterations are probably associated with hyposalivation and xerostomia, already described as a common complaint among the users of benzodiazepines. Further studies are, therefore, suggested to assess the implications of these findings on pregnant women’s oral health.
怀孕期间的生理变化可能导致唾液分泌的变化和焦虑障碍的易感性。氯硝西泮是一种苯二氮卓类药物,被推荐作为治疗焦虑症的首选药物。到目前为止,还没有研究描述使用这种药物对孕妇唾液腺的影响。因此,目的是评估暴露于氯硝西泮引起的妊娠小鼠唾液腺的改变。将22只妊娠瑞士小鼠分为对照组(C)和治疗组(T),从妊娠第5天至第17天,每天分别灌胃蒸馏水和氯硝西泮10 mg Kg-1。第18天安乐死并采集唾液腺,在光学显微镜下对唾液腺进行组织学处理和形态计量学分析。测量腺泡的面积、周长和直径以及每个腺体分泌管的厚度。参数数据(以均值和标准差表示)采用Student's t检验,非参数数据(以中位数和四分位数间距表示)采用Mann-Whitney检验(p <0.05)。腮腺腺泡直径(C: 44.1±12.2µm;T: 36.5±7.8µm;p =0.002)和导管厚度(C: 16.9[14.3-21.3]µm;T: 15.1[13.4-16.3]µm;p =0.043), T组较C组差异有统计学意义。腮腺、下颌骨和舌下腺的其他参数未见进一步改变。由此可见,氯硝西泮可引起妊娠小鼠腮腺的形态学改变。这些改变可能与低唾液和口干有关,这已经被描述为苯二氮卓类药物使用者的常见抱怨。因此,建议进一步研究以评估这些发现对孕妇口腔健康的影响。
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引用次数: 0
Attitudes towards suicidal behavior among nursing students 护生对自杀行为的态度
IF 0.2 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2022-10-21 DOI: 10.4025/actascihealthsci.v45i1.59792
Roberto Nascimento de Albuquerque, Elisa Marina Silva Araújo, Tatiana Bernardes Moreira
The existence of an association between negative attitudes from health professionals, such as prejudice, stigma and discrimination, can lead to difficulties in dealing with a person who has attempted suicide and, consequently, to a decrease in the quality of the care provided. In this context, this article aimed to verify attitudes related to suicidal behavior among nursing students at a private educational institution in the Federal District, Brazil. It was a quantitative, descriptive study that used two questionnaires: a sociodemographic and academic one, and another with questions addressing attitudes towards suicide, called Questionnaire on Attitudes Towards Suicidal Behavior. A total of 253 nursing students participated; in general, the data revealed that they did not have any negative attitude towards suicidal people. The main attitudes that brought some difficulty to students were related to: asking about suicidal behavior and inducing someone to go ahead with it; feeling helpless when faced with a person who thinks about killing themself; lack of professional preparation to deal with patients who have gone through this psychological suffering of attempting self-extermination; and the presence of a conservative and religious attitude towards suicide. Understanding the attitudes of students in the health field, especially nursing students, still in the training period, can bring about a change in the understanding of suicidal behavior, a prejudice-free nursing care, strengthen broad discussions around the topic, openly and without taboos, as well as provide a comprehensive and humanized care.
保健专业人员的消极态度,如偏见、污名化和歧视之间存在关联,可能导致在处理企图自杀的人时遇到困难,从而导致所提供护理的质量下降。在此背景下,本文旨在验证巴西联邦区私立教育机构护理学生对自杀行为的态度。这是一项定量的描述性研究,使用了两份调查问卷:一份是社会人口统计和学术调查问卷,另一份是关于自杀态度的问题,名为“自杀行为态度调查问卷”。共253名护生参与;总的来说,数据显示他们对自杀的人没有任何负面态度。给学生带来一些困难的主要态度与:询问自杀行为并诱导他人自杀;面对一个想要自杀的人感到无助;缺乏专业准备来处理那些经历过企图自杀的心理痛苦的病人;以及对自杀的保守和宗教态度。了解健康领域的学生,特别是仍处于培训阶段的护理专业学生的态度,可以改变对自杀行为的认识,实现无偏见的护理,加强围绕话题的广泛讨论,公开、无禁忌,提供全面、人性化的护理。
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引用次数: 1
The relationship of diet quality and body composition with depression level in young women 年轻女性饮食质量、身体成分与抑郁水平的关系
IF 0.2 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2022-10-21 DOI: 10.4025/actascihealthsci.v45i1.60410
H. Yardımcı, Gülperi Demir
The purpose of this study was to determine how effective diet quality and body composition are in determining depression level among university-age female students. The study was designed as a cross-sectional study and conducted on 105 university female students (mean±SD, 20.3±1.9 years old). Data were collected in face-to-face interviews using questionnaire. The statistical analysis was performed with SPSS 23.0. Univariate and multiple regression analysis was performed to determine the association between participants' BDI levels and diet quality and anthropometric measurements. It was determined that 46.7% had mild and 25.7% had moderate/severe depression symptoms (mean BDI score: 13.6±7.0). Depression scores of young women were positively affected by BMI, waist circumference, waist / height ratio, fat ratio values, and negatively affected by muscle mass (p< .05). The depression scores of young women were positively affected by the NAR energy and NAR carbohydrate scores (p< .05). The iron, calcium and omega 3 NAR scores of young women affected the depression score significantly and negatively (p< .05). This study showed that diet quality was effective in keeping the body composition within the desired values, preventing depression and so enhancing the quality of life. Improving the diet quality is important for promoting the health status and life quality.
摘要本研究旨在探讨饮食品质与身体构成对大学生抑郁程度的影响。本研究采用横断面研究设计,调查对象为105名女大学生(平均±SD, 20.3±1.9岁)。数据采用面对面访谈的方式收集。采用SPSS 23.0软件进行统计分析。进行单变量和多元回归分析,以确定参与者BDI水平与饮食质量和人体测量值之间的关系。46.7%的患者有轻度抑郁症状,25.7%的患者有中度/重度抑郁症状(平均BDI评分:13.6±7.0)。青年女性抑郁评分受BMI、腰围、腰高比、脂肪比值的正影响,受肌肉质量的负影响(p< 0.05)。年轻女性抑郁评分与NAR能量和NAR碳水化合物评分呈正相关(p< 0.05)。年轻女性的铁、钙和omega - 3 NAR评分显著负向影响抑郁评分(p< 0.05)。该研究表明,饮食质量可以有效地将身体成分保持在理想值内,防止抑郁,从而提高生活质量。改善饮食质量对提高健康状况和生活质量具有重要意义。
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引用次数: 1
Evaluation of cardiac dynamics by a mathematical law in 16 hours: application to 400 cases 用数学规律评价16小时内心脏动力学:400例应用
IF 0.2 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2022-10-21 DOI: 10.4025/actascihealthsci.v45i1.60732
J. R. Velásquez, Guillermo Trout Guardiola, S. P. Bohórquez, Ribká Soracipa Muñoz, Jairo Javier Jattin Balcázar, Ediltrudis Ramos de la Cruz
To corroborate the clinical application of an exponential mathematical law based on dynamic systems by reducing its evaluation time to 16 hours through a diagnostic concordance study with respect to the clinical conventional diagnosis. A blind study was carried out with 400 cardiac dynamics with continuous electrocardiographic recordings and Holter records, of which 150 correspond to normal patients and 250 to patients with cardiac alterations. For this, chaotic attractors of cardiac dynamics were constructed with which the fractal dimension and its spatial occupation in the generalized Box-Counting space were calculated. For normal cases, occupancy spaces between 85 and 354 were found for the Kp grid and between 45 and 342 for cases with pathologies in 16 hours, differentiating through this parameter from normality of disease. The sensitivity and specificity were 100% and the kappa coefficient was 1 when making the comparison between the diagnosis using the physical-mathematical methodology in 16 hours and the Gold Standard. The results demonstrated that by reducing its evaluation time, the exponential mathematical law diagnosed cardiac dynamics in 16 hours with the same precision as in 21 hours, corroborating its clinical applicability.
通过与临床常规诊断的诊断一致性研究,将基于动态系统的指数数学定律的评估时间缩短至16小时,从而证实其临床应用。对400例有连续心电图记录和霍尔特记录的心脏动力学进行了盲法研究,其中150例为正常患者,250例为心脏改变患者。为此,构造了心脏动力学的混沌吸引子,利用混沌吸引子计算了分形维数及其在广义Box-Counting空间中的空间占比。对于正常病例,Kp网格的占用空间在85至354之间,对于16小时内出现病理的病例,占用空间在45至342之间,通过这一参数与疾病的正常情况区分开来。用物理-数学方法诊断16小时与金标准比较,敏感性和特异性均为100%,kappa系数为1。结果表明,指数数学定律通过缩短其评估时间,在16小时内诊断心脏动力学的精度与21小时相同,证实了其临床适用性。
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引用次数: 0
Oral manifestations of systemic fungal infections: 25-year experience in an endemic region 系统性真菌感染的口腔表现:一个流行地区25年的经验
IF 0.2 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2022-04-11 DOI: 10.4025/actascihealthsci.v44i1.58157
Flávia Akemi Nakayama Henschel, Camila Camarini, M. C. Silva, L. Iwaki, Neli Pieralise, E. S. Tolentino
Some mycoses are endemic. They develop through hematogenous spread, causing a generalized infection, usually with secondary mucosal involvement.The aim of this observational and retrospective study was to report the prevalence and characteristics of oral lesions in patients diagnosed with systemic fungal infections (SFI) over a 25-year period in southern Brazil. Demographic (age, sex, ethnicity, occupation) and clinical (anatomical location, symptoms, histopathological diagnosis and management) data from the medical records of patients with SFI were collected from 1995 to 2019. 34 cases of SFI were found, of which 31 (91.18%) were diagnosed as paracoccidioidomycosis (PCM) and 3 (8.82%) as histoplasmosis. Men were much more affected (n = 31; 91.18%), with an average age of 46.9 years. Most patients (n = 18; 58.06%) were Caucasian; 48% (n = 15) were farm/rural workers and the most affected region was the jugal mucosa (n = 13; 25.49%) followed by the alveolar ridge (n = 12; 23.52%). All patients with histoplasmosis were immunocompetent men (mean age: 52.67 years), and the palate was the most affected. All patients underwent incisional biopsy and were referred to an infectologist. The dentist has an essential role in the recognition of SFI, whose oral manifestations may be the first sign. SFI should be included in differential diagnosis in patients from endemic areas. In addition, the inevitable human mobility and globalization make knowledge of these mycoses necessary worldwide, especially since advanced cases in immunocompromised patients can be fatal.
有些真菌病是地方性的。它们通过血液传播发展,引起全身性感染,通常继发累及粘膜。这项观察性和回顾性研究的目的是报告25年来巴西南部被诊断为系统性真菌感染(SFI)的患者口腔病变的患病率和特征。从1995年至2019年收集了SFI患者病历中的人口统计学(年龄、性别、种族、职业)和临床(解剖位置、症状、组织病理学诊断和管理)数据。34例SFI,其中31例(91.18%)诊断为副球孢子菌病(PCM), 3例(8.82%)诊断为组织胞浆菌病。男性受影响更大(n = 31;91.18%),平均年龄46.9岁。大多数患者(n = 18;58.06%)为白种人;48% (n = 15)为农场/农村工人,受影响最严重的是法律粘膜(n = 13);25.49%),其次是牙槽嵴(n = 12;23.52%)。所有组织胞浆菌病患者均为免疫功能正常的男性(平均年龄52.67岁),其中腭部受影响最大。所有患者均行切口活检并转诊至感染科。牙科医生在SFI的识别中起着至关重要的作用,其口腔表现可能是SFI的第一个征兆。对来自流行地区的患者,SFI应纳入鉴别诊断。此外,人类不可避免的流动性和全球化使得在世界范围内了解这些真菌病是必要的,特别是因为免疫功能低下患者的晚期病例可能是致命的。
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引用次数: 1
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