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Numerical simulation of blood fluid in hemodialysis catheters and its thrombogenic potential 血液透析导管内流体的数值模拟及其血栓形成潜力
IF 0.2 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2019-09-25 DOI: 10.4025/actascihealthsci.v41i1.45613
T. Lucas, Jonathas Haniel, R. Huebner
The present study aimed to numerically simulate blood flow within central venous catheters of hemodialysis and its thrombogenic potential. Numerical simulation research performed through the dynamic computational program of fluids. A three-dimensional geometry of right and left internal jugular veins were built, taken from the Visible Human Project®. Catheters with obstructed and unobstructed lateral holes were constructed. For the simulation, we considered the duration of the cardiac cycle of 0.8 s with pulsatile cycle of 75 beats per minute. Shear stress, velocity and pressure increased when the catheter was within the vein and when they were obstructed. At the venous orifice of the catheter that was unobstructed, the velocity increased from 0.99 ± 0.02 m s-1 to 1.79 ± 0.009 m s-1 and the pressure from 1487 ± 0.8 Pa to 3215 ± 0.7 Pa. Blood re-circulation areas have created areas of stagnation of blood flow, making it more susceptible to the development of venous thrombi. This study may contribute to the expansion of multiprofessional partnerships between health professionals and Bioengineering fields in order to study health problems that can be verified through advanced technologies. Such technologies, such as simulation programs, detail possible adverse events based on scientific evidences which often occur silently in patients.
本研究旨在数值模拟血液透析中心静脉导管内的血流及其血栓形成潜力。通过流体动力学计算程序进行数值模拟研究。建立了左右颈内静脉的三维几何形状,取自Visible Human Project®。构建具有阻塞和未阻塞侧孔的导管。在模拟中,我们考虑心脏周期的持续时间为0.8 s,脉搏周期为每分钟75次。导管在静脉内和静脉阻塞时,剪应力、速度和压力均增加。在导管静脉口通畅处,流速由0.99±0.02 m s-1增加到1.79±0.009 m s-1,压力由1487±0.8 Pa增加到3215±0.7 Pa。血液再循环区域造成了血液流动停滞的区域,使其更容易形成静脉血栓。本研究可能有助于扩大卫生专业人员与生物工程领域之间的多专业合作伙伴关系,以研究可通过先进技术验证的健康问题。这些技术,如模拟程序,根据科学证据详细说明可能发生在患者身上的不良事件。
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引用次数: 1
Benfotiamine reduces oxidative damage in muscle of endurance-trained mouse. 苯伏地明减少耐力训练小鼠肌肉的氧化损伤。
IF 0.2 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2019-09-25 DOI: 10.4025/actascihealthsci.v41i1.46888
Á. Gonçalves, R. C. Leão, F. Orsatti, G. Portari
High levels of reactive oxygen species can trigger an imbalance in redox status, which generates oxidative damage in macromolecules. The present study aimed to investigate the influence of oral supplementation with benfotiamine on oxidative stress and antioxidant activity in muscle of trained mice. Twenty-five male Balb/c mice were placed in groups. Sta-Sed: standard diet and sedentary (n = 6); Ben-Sed: benfotiamine supplemented and sedentary (n = 6); Sta-Tr: standard diet and trained (n = 6); and Ben-Tr: benfotiamine supplemented and trained (n = 7). Standard diet was AIN-93 growth and supplemented diet was AIN-93 with benfotiamine (500 mg kg-1). Trained mice were submitted to 6-weeks of endurance swimming training. The concentration of thiobarbituric acid reactive substances (TBARS), non-protein thiols, catalase (CAT) and superoxide dismutase activities (SOD) were analyzed in the gastrocnemius muscle. TBARS concentration was lower in the Ben-Tr group than in Ben-Sed and Sta-Tr groups. Thiol levels were higher in the Ben-Sed group than in the non-supplemented groups. CAT activity was more pronounced in both supplemented groups while SOD activity was higher in the Ben-Tr group than in the non-supplemented groups. The results show that benfotiamine supplementation is effective in enhancing antioxidant defenses and reducing oxidative damage in muscle of endurance-trained mouse.
高水平的活性氧会引发氧化还原状态的不平衡,从而在大分子中产生氧化损伤。本研究旨在探讨口服苯福胺对训练小鼠肌肉氧化应激和抗氧化活性的影响。将25只雄性Balb/c小鼠分为两组。Sta-Sed:标准饮食和久坐(n = 6);Ben-Sed:补充苯福胺且久坐(n = 6);Sta-Tr:标准饮食和训练(n = 6);本- tr:添加和训练苯福胺(n = 7)。标准饲粮为AIN-93生长饲粮,补充饲粮为AIN-93加苯福胺(500 mg kg-1)。训练后的小鼠进行为期6周的耐力游泳训练。测定大鼠腓肠肌中硫代巴比妥酸活性物质(TBARS)、非蛋白硫醇、过氧化氢酶(CAT)和超氧化物歧化酶(SOD)活性。Ben-Tr组TBARS浓度低于Ben-Sed和Sta-Tr组。本- sed组的硫醇含量高于未补充组。CAT活性在两种补充组中都更为明显,而SOD活性在Ben-Tr组中高于未补充组。结果表明,补充苯福胺能有效增强耐力训练小鼠肌肉的抗氧化防御能力,减少氧化损伤。
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引用次数: 0
Hypertensive elderly people: assessing the quality of life 高血压老年人:生活质量评估
IF 0.2 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2019-09-11 DOI: 10.4025/actascihealthsci.v41i1.44652
Larissa Cristina Rodrigues Alencar, A. Sardinha
The objective of the present study was to evaluate the quality of life in hypertensive elderly people assisted in the Family Health Strategy. This is a descriptive, exploratory, cross-sectional study, with quantitative approach. The participants were 544 hypertensive elderly patients. The instruments used for data collection were the sociodemographic form and the WHOQOL-BREF. Regarding the socioeconomic and demographic characteristics of the elderly participants of this study, there was prevalence of elderly women, aged 60-69 years, self-reported white, catholic religion, illiterates, coming from municipalities in the countryside of the state, married/stable union, retired, income of one minimum wage, with children, non-smokers, non-alcohol consumers. Regarding the quality of life, the highest score was obtained in the Social Relationships Domain, followed by the Psychological Domain, Physical Domain and lower score in the Environmental Domain. The results show that the elderly participants presented a good quality of life and, although they have high blood pressure levels, they seek to live as best as possible.
本研究的目的是评估在家庭健康战略协助下的高血压老年人的生活质量。这是一项描述性、探索性、横断面研究,采用定量方法。研究对象为544例老年高血压患者。用于数据收集的工具是社会人口学表格和WHOQOL-BREF。关于本研究老年参与者的社会经济和人口特征,普遍存在老年妇女,年龄在60-69岁之间,自我报告为白人,天主教,文盲,来自国家农村的市政当局,已婚/稳定的工会,退休,收入最低工资,有子女,不吸烟,不饮酒。在生活质量方面,社会关系领域得分最高,其次是心理领域、身体领域,环境领域得分较低。结果显示,老年参与者表现出良好的生活质量,尽管他们有高血压,但他们尽可能地追求最好的生活。
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引用次数: 0
Association between weight loss and clinical-pathologic factors in oncological patients in chemotherapy treatment: a longitudinal study 肿瘤患者化疗期间体重减轻与临床病理因素的关系:一项纵向研究
IF 0.2 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2019-09-11 DOI: 10.4025/actascihealthsci.v41i1.44263
Débora Fernandes Pinheiro, Simone Carla Benincá, Caryna Eurich Mazur, E. Meira, Jéssica Wouk
The present study aimed to evaluate the nutritional state and WL of individuals with cancer. Is a longitudinal observational study was performed with patients assisted in the oncological ambulatory. Sample was composed of 402 patients, with an average of 58.46±13.60 years old, 56.5% women and the majority elderly (51.74%). Regarding tumor localization, 12.9% were found in the head and neck, 22.6% in mamas, 10.2% in the lungs, 29.4% in the gastrointestinal tract (GI tract) and 29.4% in other body parts. A gradual fall of nutritional state in relation to BMI was observed, and the patients were advancing to malnutrition. When severe and not severe WL were correlated, a statistical difference was demonstrated regarding age, current and habitual weight, as well as the corresponding BMI (p<0.05).  Overweight and obese patients presented a higher severe WL than the other group (p<0.05). However, 67.34% of patients presented WL and a following nutritional state alteration, being cancer in the GI tract with a significant difference, 37.44% (p<0.05) with severe WL (p<0.000). Patients diagnosed with cancer, especially in the GI tract, treated with chemotherapy have higher chances of WL, which trigger a reduction of survival rate, being obesity and age reliable predictors of a consequent severe WL.
本研究旨在评估癌症患者的营养状况和WL。这是一项纵向观察研究,在肿瘤门诊协助患者进行。样本由402例患者组成,平均年龄58.46±13.60岁,女性56.5%,老年人占多数(51.74%)。在肿瘤定位方面,头颈部12.9%,乳腺22.6%,肺部10.2%,胃肠道29.4%,其他部位29.4%。与BMI相关的营养状况逐渐下降,并向营养不良进展。重度WL与非重度WL相关时,年龄、当前体重、习惯体重以及相应的BMI均有统计学差异(p<0.05)。超重和肥胖患者的严重WL高于其他组(p<0.05)。然而,有67.34%的患者出现WL并随后出现营养状态改变,为胃肠道肿瘤,两者差异有统计学意义,有37.44% (p<0.05)为重度WL (p<0.000)。被诊断为癌症的患者,特别是在胃肠道中,接受化疗的患者有更高的WL机会,这会导致生存率的降低,肥胖和年龄是随后严重WL的可靠预测因素。
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引用次数: 0
Mortality and years of life lost to suicide in Rio Grande do Norte, Brazil, 2000-2015 2000-2015年巴西北里奥格兰德州自杀死亡率和死亡年数
IF 0.2 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2019-09-11 DOI: 10.4025/actascihealthsci.v41i1.45972
Emelynne Gabrielly de Oliviera Santos, K. G. Vedana, I. Barbosa
Analyze the epidemiological profile of and years of life lost to suicide in Rio Grande do Norte, Brazil, from 2000 to 2015. This is an ecological study in which data on death were sourced from the Mortality Information System. Years of Potential Life Lost were calculated over the historical series. A total of 2,266 deaths by suicide were analyzed, identified during the period, with the most frequent cases being those occurring at home, by hanging, among men, black people, single people and the elderly. More Years of Potential Life Lost were counted in the economically active age group (30-39 years old). Thus, recognizing the epidemiological characteristics of suicide in Rio Grande do Norte may guide more effective actions and strategies targeting risk populations and reinforces the need for further studies focusing on regions with the highest rates in the state. Moreover, mental health care must be adapted to age and gender, besides approaching social support needs and feeling of belonging.
分析2000年至2015年巴西北里奥格兰德州自杀的流行病学概况和死亡年数。这是一项生态学研究,其中死亡数据来自死亡率信息系统。潜在生命损失年数是根据历史序列计算的。在此期间,共分析和确定了2 266例自杀死亡,其中最常见的是男性、黑人、单身人士和老年人在家中以上吊方式死亡。在经济活跃年龄组(30-39岁)中计算潜在寿命损失年数。因此,认识到北里奥格兰德州自杀的流行病学特征可能会指导针对危险人群的更有效的行动和策略,并加强对该州最高自杀率地区的进一步研究的必要性。此外,除了满足社会支持需求和归属感外,心理保健还必须适应年龄和性别。
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引用次数: 0
Patient self-care with double catheter lumen for hemodialization: validation of instructional folder 患者自我护理双管腔血液透析:验证指导手册
IF 0.2 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2019-09-11 DOI: 10.4025/actascihealthsci.v41i1.47558
Sayonnara Ferreira Maia, Daniely Matias Facundes, Amanda Lorena Lima Carneiro
The use of venous catheters for hemodialysis is associated with high rates of morbidity and mortality in patients with chronic renal failure. The implant of the dual lumen catheter (DLC) assists the patient in a worsening situation but commonly the patient remains with the DLC back home and this requires a series of important measures. The use of printed educational materials becomes an important tool to assist this type of care. Thus, the objective was to create and validate an instructive folder for the self-care of the patient using a catheter for hemodialysis. It is a methodological study of creation and evaluation of technology, in three stages. For validation of the content and style the material was submitted to the evaluation by experts in the area. 92.3% of the participants stated that the folder demonstrates clarity in their language, 53.8% of the participants suggested change and addition of information, and the same percentage also states that the instrument is attractive. The main suggestions were to change some term/word used in the folder, suggest changes to the images used, and include some information in the content. It is presumed then that the use of educational materials results in benefits to the patients who will receive the guidelines for self-care. Thus, the importance of nurses to use these resources for chronic renal patient care is emphasized.
使用静脉导管进行血液透析与慢性肾衰竭患者的高发病率和死亡率相关。双腔导管(DLC)的植入有助于患者在病情恶化的情况下,但通常患者仍然使用DLC回家,这需要一系列重要措施。使用印刷的教育材料成为协助这类护理的重要工具。因此,目的是创建和验证一个指导文件夹的自我护理患者使用导管进行血液透析。它是对技术创造和评价的方法论研究,分为三个阶段。为了验证内容和风格,材料被提交给该领域的专家进行评估。92.3%的参与者表示,该文件夹表明他们的语言清晰,53.8%的参与者建议改变和增加信息,同样比例的参与者还表示,该工具很有吸引力。主要建议是更改文件夹中使用的一些术语/单词,建议更改使用的图像,并在内容中包含一些信息。因此可以假定,使用教育材料对接受自我保健指导方针的患者有益。因此,强调了护士利用这些资源对慢性肾病患者进行护理的重要性。
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引用次数: 2
Analysis of pre-competitive anxiety of Brazilian young swimmers 巴西青少年游泳运动员赛前焦虑分析
IF 0.2 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2019-07-04 DOI: 10.4025/ACTASCIHEALTHSCI.V41I1.45475
Glauber Castelo Branco Silva, Antônio Carlos Leal Cortez, J. N. Junior, Carla Thamires Laranjeira Granja, E. Conde, G. F. Melo
This study analyzed the level of state-anxiety of swimming athletes based on sex, category, competitive specialty, competitive level and competitive experience. Participants were 178 male (n = 105) and female (n = 73) swimmers with mean age of 15.51 ± 1.9 years at regional, national and international levels. The Competitive State Anxiety Inventory-2 (CASI-2) was used as instrument. Data analysis was conducted using the independent Student’s t-test, Mann-Whitney, Kruskal-Wallis and Spearman correlation. The results showed higher levels of self-confidence in males (p = 0.02) and higher levels of cognitive anxiety in females (p = 0.019). Among the competitive specialties, there were differences between levels of cognitive anxiety (p = 0.045) and self-confidence (p = 0.041) of swimmers. Differences were also observed in levels of cognitive anxiety (p = 0.049), somatic anxiety (p = 0.001) and self-confidence (p = 0.047) between swimming competition levels. It was concluded that male swimmers are more self-confident and less anxious than female swimmers and there are different levels of self-confidence and types of anxiety for different competitive specialties and ranking of competitions.
本研究以性别、类别、竞技专业、竞技水平和竞技经验为基础,分析了游泳运动员的状态焦虑水平。研究对象为178名男性(n = 105)和女性(n = 73),平均年龄为15.51±1.9岁,来自地区、国家和国际水平的游泳运动员。采用竞争状态焦虑量表(CASI-2)。数据分析采用独立的学生t检验、Mann-Whitney、Kruskal-Wallis和Spearman相关。结果显示,男性的自信心水平较高(p = 0.02),女性的认知焦虑水平较高(p = 0.019)。在竞技专业中,游泳运动员的认知焦虑水平(p = 0.045)和自信水平(p = 0.041)存在差异。在游泳比赛水平之间,认知焦虑(p = 0.049)、躯体焦虑(p = 0.001)和自信(p = 0.047)水平也存在差异。结果表明,男性游泳运动员比女性游泳运动员更自信、焦虑程度更低,且在不同的比赛专业和比赛等级上,男性游泳运动员的自信程度和焦虑类型有所不同。
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引用次数: 3
Prediction of body image dissatisfaction in university students by multivariate statistical methods 多元统计方法预测大学生身体意象不满意
IF 0.2 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2019-07-04 DOI: 10.4025/ACTASCIHEALTHSCI.V41I1.44186
Vinícius Rodrigues Arruda Pinto, Laura Fernandes Melo, J. Bressan
Overweight and obesity are responsible for significant costs of the Brazil’s public health system and can modify the self-perception of the body image, attitudes, cognitions and thoughts. This study intends to propose predictive models to evaluate factors related to body image dissatisfaction among university students. Undergraduate students, with a mean age of 22.4 years, were interviewed in Minas Gerais, Brazil, by means of a behavioral questionnaire and evaluated the body image by scale of figures of silhouettes according to the Brazilian biotype. Contingency analysis pointed out dissatisfaction in 67.1% of the students and the time dedicated to sedentary activities presented significant influence on body image. Female undergraduate students from health science courses with recent weight gain tended to wish smaller silhouettes, while male students wished larger body sizes. Multinomial and logistic regression analyses revealed a good predictive power, but the multinomial regression was more advantageous and effective in demonstrating a satisfactory predictive model comprised of a larger number of variables to explain the body image dissatisfaction.
超重和肥胖造成巴西公共卫生系统的巨大成本,并可能改变对身体形象、态度、认知和思想的自我感知。本研究拟提出预测模型,评估大学生身体意象不满意的相关因素。采用行为问卷法对巴西米纳斯吉拉斯州的大学生进行调查,平均年龄22.4岁,并根据巴西人的生物类型,采用轮廓比例法对大学生的身体形象进行评价。权变分析指出67.1%的学生不满意,久坐时间对身体形象有显著影响。最近体重增加的健康科学专业的女本科生倾向于希望身材更小,而男学生则希望身材更大。多项回归和逻辑回归分析显示了良好的预测能力,但多项回归更有利,更有效地展示了一个由更多变量组成的令人满意的预测模型来解释身体形象不满意。
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引用次数: 0
Mortality rate for cervical cancer in Brazil and socioeconomic indicators: a spatial study 巴西宫颈癌死亡率和社会经济指标:一项空间研究
IF 0.2 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2019-07-04 DOI: 10.4025/ACTASCIHEALTHSCI.V41I1.45388
Héllyda de Souza Bezerra, Tatiana de Medeiros Carvalho Mendes, Talita Araujo Souza, F. B. Andrade
The objective of the study was to analyze the correlation between the mortality rate from cervical cancer with schooling, Gini index and Human Development Index (HDI). This is an epidemiological, retrospective, observational and ecological study carried out in the 161 intermediate regions of urban articulation in Brazil. The study was based on secondary data from DATASUS and the United Nations Development Program. The spatial analysis of mortality versus schooling, Gini index and HDI was performed. Most municipalities in Brazil with high mortality rate are located in the North and Northeast. In addition, it was observed that schooling, Gini index and HDI directly influence the increase or reduction of mortality. Knowing these fragilities and their distribution in Brazil is necessary to solve the problems and improve the indicators such as the mortality rate.
本研究的目的是分析宫颈癌死亡率与学校教育、基尼指数和人类发展指数(HDI)之间的关系。这是一项流行病学、回顾性、观察性和生态学研究,在巴西161个城市衔接的中间区域进行。这项研究基于来自DATASUS和联合国开发计划署的二手数据。死亡率与学校教育、基尼指数和人类发展指数的空间分析。巴西死亡率高的大多数城市位于北部和东北部。此外,还观察到学校教育、基尼指数和人类发展指数直接影响死亡率的增减。了解这些脆弱性及其在巴西的分布对于解决问题和改善死亡率等指标是必要的。
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引用次数: 0
Early childhood education professionals’ knowledge about prevention, detection and treatment of acute respiratory infections in children 幼儿教育专业人员对儿童急性呼吸道感染的预防、检测和治疗知识
IF 0.2 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2019-07-04 DOI: 10.4025/ACTASCIHEALTHSCI.V41I1.43759
P. D. Santos, Franciele Cascaes da Silva, Bruna Weber Santos, C. Schivinski
The present study aimed to identify and compare knowledge and practices of early childhood education professionals from three public nursery schools (A, B and C) in the city of Florianópolis/SC relative to prevention, early detection and handling of acute respiratory infections (ARIs) in children aged between zero and six years old. A total of 120 educators answered a questionnaire. The instrument was composed of 15 close- and open-ended questions, five of which were scored. In statistical analyses, the Anova One-Way test revealed no significant differences for knowledge between professionals from the three institutions, with nursery school B having the highest mean score (6.12 ± 0.8), showing fair knowledge about child care. Overall results point to existing gaps concerning the need for guidance on these aspects of a child’s health.
本研究旨在确定和比较Florianópolis/SC市三所公立幼儿园(A, B和C)的幼儿教育专业人员在0至6岁儿童急性呼吸道感染(ARIs)的预防,早期发现和处理方面的知识和实践。共有120名教育工作者回答了一份问卷。该工具由15个封闭式和开放式问题组成,其中5个问题得分。在统计分析中,单因素方差分析显示,三所机构的专业人员对儿童保育知识的了解程度无显著差异,其中B幼儿园的平均得分最高(6.12±0.8),显示出对儿童保育知识的了解程度。总体结果表明,在需要就儿童健康的这些方面提供指导方面存在差距。
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引用次数: 0
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