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Histiocytoses and Mastocytoses 组织细胞增多和肥大细胞增多
IF 1.9 Q3 DERMATOLOGY Pub Date : 2022-01-01 DOI: 10.1007/978-3-030-82820-2_26
W. Kempf, M. Hantschke, H. Kutzner
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引用次数: 0
Artifactual Damage Artifactual损害
IF 1.9 Q3 DERMATOLOGY Pub Date : 2022-01-01 DOI: 10.1007/978-3-030-82820-2_17
W. Kempf, M. Hantschke, H. Kutzner
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引用次数: 0
Dermis - Degenerative and Metabolic Disorders 真皮-退行性和代谢紊乱
IF 1.9 Q3 DERMATOLOGY Pub Date : 2022-01-01 DOI: 10.1007/978-3-030-82820-2_13
W. Kempf, M. Hantschke, H. Kutzner
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引用次数: 0
Epithelial Cysts 上皮囊肿
IF 1.9 Q3 DERMATOLOGY Pub Date : 2022-01-01 DOI: 10.1007/978-3-030-82820-2_18
W. Kempf, M. Hantschke, H. Kutzner
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引用次数: 0
Epidermis Acantholysis 表皮皮肤棘层松解
IF 1.9 Q3 DERMATOLOGY Pub Date : 2022-01-01 DOI: 10.1007/978-3-030-82820-2_6
Werner Kempf, Markus Hantschke, H. Kutzner
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引用次数: 0
Dermis Diffuse Mixed Inflammatory Infiltrates 真皮弥漫性混合炎性浸润
IF 1.9 Q3 DERMATOLOGY Pub Date : 2022-01-01 DOI: 10.1007/978-3-030-82820-2_12
W. Kempf, M. Hantschke, H. Kutzner
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引用次数: 0
Cutaneous Metastases 皮肤转移
IF 1.9 Q3 DERMATOLOGY Pub Date : 2022-01-01 DOI: 10.1007/978-3-030-82820-2_27
W. Kempf, M. Hantschke, H. Kutzner
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引用次数: 0
Pseudocysts 假囊
IF 1.9 Q3 DERMATOLOGY Pub Date : 2022-01-01 DOI: 10.1007/978-3-030-82820-2_19
Werner Kempf, Markus Hantschke, H. Kutzner
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引用次数: 1
Allopurinol-Induced Oral Lichenoid Drug Reaction with Complete Regression after Drug Withdrawal 别嘌醇诱导的口服类地衣药物反应停药后完全消退
IF 1.9 Q3 DERMATOLOGY Pub Date : 2020-08-12 DOI: 10.3390/dermatopathology7010004
Alexandre Perez, Benjamin Lazzarotto, J. Carrel, T. Lombardi
Background: Lichen planus is a chronic mucocutaneous inflammatory disease. Oral manifestations are common, and may remain exclusive to the oral mucosa without involvement of the skin or other mucosae. A differential diagnosis includes oral lichenoid drug reactions. Allopurinol, which is the first line hypo-uricemic treatment, is often quoted as being a possible offending drug, though oral reactions have rarely been reported. Case presentation: We describe a 59-year-old male gout patient, successfully treated with allopurinol, who developed acute onset of oral lichenoid lesions, involving bilaterally the buccal mucosa, the tongue and the labial mucosa. Histopathology was consistent with a lichen planus or a drug-induced lichenoid reaction. Improvement of the patient’s condition after withdrawal of allopurinol confirmed the lichenoid nature of the lesion. Remission was complete after a few weeks. Discussion: Although unusual, allopurinol may induce a lichenoid drug reaction. These reactions may mimic clinically and histopathologically idiopathic lichen planus. Improvement or complete regression of the lesions may be attempted to confirm the diagnosis. According to the latest WHO recommendations, these lesions have a potential for malignant transformation.
背景:扁平苔藓是一种慢性皮肤粘膜炎症性疾病。口腔表现是常见的,并且可能仅限于口腔粘膜,而不涉及皮肤或其他粘膜。鉴别诊断包括口腔类地衣药物反应。别嘌醇是治疗高尿酸血症的一线药物,通常被认为是一种可能的不良药物,尽管很少有口服反应的报道。病例介绍:我们描述了一名59岁的男性痛风患者,他成功地接受了别嘌呤醇治疗,出现了急性发作的口腔苔藓样病变,涉及双侧颊粘膜、舌头和唇粘膜。组织病理学与扁平苔藓或药物诱导的类地衣反应一致。停药别嘌醇后患者病情的改善证实了病变的地衣性质。几周后病情完全缓解。讨论:别嘌呤醇虽然不常见,但可能会引起类地衣药物反应。这些反应可能在临床和组织病理学上模拟特发性扁平苔藓。可以尝试病变的改善或完全消退来确认诊断。根据世界卫生组织的最新建议,这些病变具有恶性转化的潜力。
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引用次数: 2
Lichenoid Keratosis-Like Melanoma: A Clinically and Histopathologically Challenging Lesion 苔藓样角化样黑色素瘤:一种临床和组织病理学上具有挑战性的病变
IF 1.9 Q3 DERMATOLOGY Pub Date : 2020-08-06 DOI: 10.1159/000506914
M. Sahil, Y. Ibrahim, G. Kaya
Regressive melanoma with lichenoid tissue reaction may be clinically and histopathologically challenging. A 73-year-old male visited our clinic for a general skin checkup. We noticed a red papule on the right side of his back. On dermatoscopy, scattered grayish dots were observed. The differential diagnosis included lichenoid keratosis and melanoma. Histopathological examination of the excised lesion showed a regressive melanoma with a histopathological pattern of lichenoid keratosis.
伴有苔藓样组织反应的复发性黑色素瘤可能在临床和组织病理学上具有挑战性。一位73岁的男性到我们诊所做全身皮肤检查。我们注意到他背部右侧有一个红色丘疹。在皮肤镜检查中,观察到分散的灰点。鉴别诊断包括苔藓样角化病和黑色素瘤。切除病变的组织病理学检查显示为退行性黑色素瘤,组织病理学模式为苔藓样角化病。
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引用次数: 0
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Dermatopathology
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