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Calcium Jacket of Left Ventricle: An Aristocracy of the Monster 左心室钙外套:怪物中的贵族
Pub Date : 2023-08-25 DOI: 10.1177/26324636231194886
Sudipta Mondal, Richard R. Raj, S. Harikrishnan
Extensive myocardial dystrophic calcification is rare and indicates a poor prognosis with a risk of arrhythmia and recurrent heart failure. We present a long term survivor of extensive myocardial infarction presenting as myocardial calcification related unstable ventricular tachycardia needing an implantable cardioverter defibrillator.
广泛的心肌营养不良钙化是罕见的,表明预后不良,有心律失常和心力衰竭复发的危险。我们报告了一个广泛的心肌梗死的长期幸存者,表现为心肌钙化相关的不稳定室性心动过速,需要植入式心律转复除颤器。
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引用次数: 0
Massive Pulmonary Artery Aneurysm in a Patient with Ventricular Septal Defect: Case Report of a Rare Association 室间隔缺损患者的巨大肺动脉动脉瘤:罕见关联病例报告
Pub Date : 2023-08-18 DOI: 10.1177/26324636231193999
Anish Pabba, K. Parvathareddy, Praveen Nagula, Susruth Bandaru
A pulmonary artery aneurysm is defined as focal dilation of the pulmonary artery beyond a diameter of 29 mm. The reported incidence is 1 in 14,000 as per the autopsy studies. A diameter of more than 55 mm is defined as a massive pulmonary artery aneurysm which is very rare. These are commonly associated with patent ductus arteriosus. No distinct features for identification and guidelines for their management warrant a detailed evaluation for etiology and close follow-up in this entity fearing fatal rupture. We present a case of a massive pulmonary artery aneurysm associated with the ventricular septal defect.
肺动脉动脉瘤定义为肺动脉直径超过29mm的局灶性扩张。根据尸检研究,报告的发病率为1 / 14000。直径大于55mm的被定义为巨大的肺动脉动脉瘤,这是非常罕见的。这些通常与动脉导管未闭有关。没有明确的识别特征和管理指南,需要对该实体的病因进行详细评估和密切随访,以免发生致命的破裂。我们提出一个巨大的肺动脉动脉瘤合并室间隔缺损的病例。
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引用次数: 0
Chat GPT—a Boon or Bane to Academic Cardiology? gpt是学术心脏病学的福音还是祸根?
Pub Date : 2023-08-17 DOI: 10.1177/26324636231185644
Rajesh Natuva, Srinivas Puppala
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引用次数: 1
Endovenous Intervention for Isolated Idiopathic Non-Malignant High-Grade Stenosis of the Suprahepatic Inferior Vena Cava for Chronic Venous Congestion 慢性静脉充血孤立性特发性非恶性高度肝上下腔静脉狭窄的静脉内介入治疗
Pub Date : 2023-08-13 DOI: 10.1177/26324636231191313
P. Jariwala, Venugopal Rao Joginpalli, Venkateswaralu Jampala
A high-grade stenosis of the inferior vena cava (IVC) can cause swelling, discoloration of the lower extremities, and the development of venous ulcers. These patients may be unable to participate in physical activities as well. Although anticoagulation and compression therapy may help alleviate symptoms and prevent repeated thrombosis, few patients develop progressive symptoms. We present a case of an elderly female who had progressive venous claudication, edema, heaviness, and discoloration of both lower limbs. Despite endovascular laser therapy for varicose veins, the symptoms worsened, jeopardizing her quality of life. Endovenous intervention with a stent to treat high-grade stenosis at the junction of the suprahepatic IVC and right atrium (RA) could completely relieve her symptoms and improve her quality of life. Isolated severe stenosis of the IVC at the confluence with the RA is a rare cause of chronic venous congestion. Its leads to refractory venous congestion with secondary skin change with an adverse impact on quality of life. Endovenous intervention using an appropriate endovascular prosthesis is the treatment of choice.
高度狭窄的下腔静脉(IVC)可引起肿胀,下肢变色和静脉溃疡的发展。这些患者也可能无法参加体育活动。虽然抗凝和压迫治疗可能有助于缓解症状和防止血栓复发,但很少有患者出现进行性症状。我们提出一个老年女性谁有进行性静脉跛行,水肿,沉重,和变色的双下肢。尽管血管内激光治疗静脉曲张,症状恶化,危及她的生活质量。静脉内支架介入治疗肝上腔静脉与右心房交界高度狭窄,可完全缓解患者症状,改善患者生活质量。孤立严重狭窄的下腔静脉与类风湿性关节炎的汇合处是一个罕见的原因慢性静脉充血。它导致难治性静脉充血和继发性皮肤改变,对生活质量产生不利影响。使用适当的血管内假体进行静脉内介入治疗是治疗的选择。
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引用次数: 0
Torsades De Pointes Complicating Acute Myocardial Infarction, Twisting the Prognosis 扭转点并发急性心肌梗死,扭转预后
Pub Date : 2023-08-07 DOI: 10.1177/26324636231190247
Tammiraju Iragavarapu, K. Krishna
Introduction Torsades de pointes (TdP), a form of polymorphic ventricular tachycardia that manifests in the setting of an acquired or congenital QT interval prolongation. Polymorphic VT can occur in hyper acute phase or healing phase of an acute myocardial infarction. The presence of necrotic area caused by the infarction explains the existence of a possible circuit as well as the appearance of a re-entry arrhythmia. Aims and Objectives Our aim is to study the incidence of long Qt induced TdP in acute MI patients and its prognostic implications. We also want to analyze the impact of primary percutaneous transluminal coronary angioplasty in the management of these subset of patients. Methods In this cross-sectional observational study done from May 2021 to May 2022, We have studied 320 cases of acute MI, of which 6 were found to have TdP (1.9%). Four patients had inferior wall myocardial infarction and 2 patients had Non-ST elevation MI. Thrombolysis was done in 2 cases. Two cases underwent primary angioplasty. One case was recommended for coronary artery bypass grafting. All cases underwent appropriate electrolyte correction, besides cardioversion, as needed. Results All patients with TdP had prolonged QT interval. 50% of patients had mild hypokalemia. Two patients had complete heart block. Three patients had severe left ventricular dysfunction. Patients who underwent primary angioplasty survived. Thrombolysis had less impact on survival in Acute Mi with TdP. Conclusion Early percutaneous coronary angioplasty, combined with electrolyte correction, improves the prognosis in TdP complicating acute MI.
点扭转性心动过速(TdP)是一种多形态室性心动过速,表现为获得性或先天性QT间期延长。多形性室速可发生在急性心肌梗死的超急性期或愈合期。梗死引起的坏死区域的存在解释了可能的回路的存在以及再入性心律失常的出现。目的和目的我们的目的是研究急性心肌梗死患者长Qt间期诱发TdP的发生率及其预后意义。我们还想分析初级经皮腔内冠状动脉成形术对这类患者的影响。方法在2021年5月至2022年5月进行的横断面观察研究中,我们研究了320例急性心肌梗死,其中6例发现TdP(1.9%)。4例为下壁心肌梗死,2例为非st段抬高型心肌梗死,2例行溶栓治疗。2例行原发性血管成形术。1例建议行冠状动脉旁路移植术。根据需要,除复律外,所有病例均行适当的电解质矫正。结果TdP患者QT间期均延长。50%的患者有轻度低钾血症。2例患者出现完全性心脏传导阻滞。3例患者有严重的左心室功能障碍。接受初级血管成形术的患者存活。溶栓对急性心肌梗死合并TdP患者的生存影响较小。结论早期经皮冠状动脉成形术联合电解质矫正可改善TdP合并急性心肌梗死的预后。
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引用次数: 0
STEMI: Wolf in Sheep’s Clothing With Double-Barrel Aorta 披着羊皮的狼,有双主动脉
Pub Date : 2023-08-07 DOI: 10.1177/26324636231190170
Sudipta Mondal, Harikrishnan Sivadasanpillai
Acute aortic dissection is a life-threatening condition with high mortality if not treated immediately. We present a case of acute aortic dissection presenting as acute ST elevation myocardial infarction causing Cath Lab misadventure and delay in the definitive management.
急性主动脉夹层是一种危及生命的疾病,如果不立即治疗,死亡率很高。我们报告一例急性主动脉夹层表现为急性ST段抬高型心肌梗死,导致Cath实验室的失误和最终治疗的延误。
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引用次数: 0
Hemodynamic and Management Perspectives in Heart Failure Patients 心力衰竭患者的血流动力学和治疗观点
Pub Date : 2023-07-27 DOI: 10.1177/26324636231185645
K. Parvathareddy, Praveen Nagula
Introduction Prevalence of heart failure (HF) is increasing, and right ventricular (RV) dysfunction is an independent predictor of mortality. Accurate echocardiographic evaluation of RV function is challenging and novel parameters which can aid in prediction RV function are required. Pulmonary artery Pulsatility index (PAPi) is one such parameter. Patients and Methods We conducted a prospective study in 33 patients admitted with symptoms of HF and severe LV dysfunction (EF < 35) who underwent right heart catheterization and followed them for 6 months. Primary objective was to determine the association of PAPi with hospitalizations and mortality in short-term follow-up in HF patients. Clinical, demographic, echocardiographic, and catheterization data were recorded. PAPi was calculated as a ratio of pulmonary artery pulse pressure and right atrial pressure. Results The mean age of population was 47 years (±12). Males were 20(61%) and females were 13(39%). Median PAPi in the study population was 2.42 (IQR-1.83). The study population were stratified into 3 groups based on 10th, 50th, and 90th percentile PAPi and on comparisons between groups PAPi was significantly associated with hospitalization at 1 and 6 months in univariate (P = .03 and P = .03 respectively) and in multivariate analysis (P = .04). PAPi was not found to be associated with mortality at 1 month or 6 months. However, the absolute mortality was low in the study population (n = 4). Conclusion PAPi has been found to be a strong and an independent predictor of hospitalization at 1 month and 6 months. Comments Advanced HF is seen in 1 out of 5 patients with HF. It is characterized by refractory symptoms, multiple hospitalizations, fluid retention, elevated natriuretic peptides, and decreased cardiac output often requiring inotropes. The survival rate is poor. The presence of right ventricular dysfunction is an independent predictor of mortality in these patients. Hemodynamic assessment is of importance in these patients to guide regarding further management, ie, use of inotropes, left ventricular assist devices, etc. The PAPi is a marker derived from the formula (PASP-PADP/RAP). 1 The outcome worsens as the PAPi decreases. However, the stroke volume, pulmonary artery capacitance (PAC), and right atrial pressure all have an impact on PAPi. Patients with high PAC will have better PAPi compared to those with low PAC with the stroke volume being constant. 2 Different subsets of HF population have varying PAPI thresholds, with isolated RV infarction having the lowest (0.9) and severe HF having the highest (3.2). 2 Future research should examine the impact of exercise, inotropes, and vasodilators.
心衰(HF)的患病率正在上升,右心室(RV)功能障碍是死亡率的独立预测因子。超声心动图对右室功能的准确评价具有挑战性,需要新的参数来帮助预测右室功能。肺动脉搏动指数(PAPi)就是这样一个参数。患者和方法我们对33例有心衰症状和严重左室功能障碍(EF < 35)的患者进行了前瞻性研究,并对他们进行了6个月的随访。主要目的是在心衰患者的短期随访中确定PAPi与住院和死亡率的关系。记录临床、人口统计学、超声心动图和导管数据。PAPi计算为肺动脉脉压与右心房压之比。结果患者平均年龄47岁(±12岁)。男性20例(61%),女性13例(39%)。研究人群的中位PAPi为2.42 (IQR-1.83)。根据第10、第50和第90百分位PAPi以及组间比较,将研究人群分为3组,在单因素分析(P = 0.03和P = 0.03)和多因素分析(P = 0.04)中,PAPi与1个月和6个月住院率显著相关。未发现PAPi与1个月或6个月时的死亡率相关。然而,研究人群的绝对死亡率较低(n = 4)。结论PAPi已被发现是1个月和6个月住院的一个强大且独立的预测因子。晚期HF见于1 / 5的HF患者。其特点是难治性症状、多次住院、液体潴留、利钠肽升高、心输出量减少,通常需要使用肌力药物。存活率很低。右心室功能障碍的存在是这些患者死亡率的独立预测因子。血流动力学评估对这些患者的进一步治疗具有重要指导意义,即使用收缩性药物、左心室辅助装置等。PAPi是由公式(PASP-PADP/RAP)衍生的标记物。结果随着PAPi的降低而恶化。然而,卒中容量、肺动脉电容(PAC)和右房压均对PAPi有影响。在卒中容量不变的情况下,高PAC患者的PAPi优于低PAC患者。2 HF人群的不同亚群具有不同的PAPI阈值,孤立性RV梗死最低(0.9),重度HF最高(3.2)。未来的研究应检查运动、肌力和血管扩张剂的影响。
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引用次数: 0
Missed Cardiac Amyloidosis: A Potentially Treatable Disease 漏诊的心脏淀粉样变性:一种潜在可治疗的疾病
Pub Date : 2023-07-21 DOI: 10.1177/26324636231186910
B. Vivek, Ashish Kumar Jain, J. Sawhney, R. Jain, R. Passey, A. Mohanty
Aim To highlight the prevailing lack of suspicion of cardiac amyloidosis (CA) amongst physicians, leading to preventable delay in management of patients of heart failure (HF). Methods Six patients of CA diagnosed in 6 months were retrospectively analyzed. Clinical history, investigations, treatment, and follow-up data is analyzed. Result A speckled interventricular septum on echo favored CA. Speckle tracking showed reduced global longitudinal strain with typical left ventricular apical sparing in all patients. Bone marrow study confirmed light chain amyloidosis (AL) in all patients. Conclusion CA, a frequently missed diagnosis, can be detected early with the help of clinical red flag signs, echocardiogram, serum and urine immune electrophoresis and bone scan.
目的强调医生普遍缺乏对心脏淀粉样变性(CA)的怀疑,导致心力衰竭(HF)患者管理的可预防延误。方法对6例6个月确诊的CA患者进行回顾性分析。分析临床病史、调查、治疗和随访资料。结果超声显示室间隔斑点有利于CA。斑点追踪显示所有患者的整体纵向应变减少,并伴有典型的左心室心尖保留。骨髓研究证实所有患者均为轻链淀粉样变性(AL)。结论CA易漏诊,可通过临床红旗征象、超声心动图、血清、尿免疫电泳及骨扫描早期发现。
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引用次数: 1
“Retrograde Plaque/Flap Lift-and-Shift” Technique to Exclude Coronary Artery Aneurysm at the Proximal Cap of Chronic Total Occlusion of the Right Coronary Artery: A Case Report “逆行斑块/皮瓣升降移位”技术排除慢性右冠状动脉全闭塞近端冠状动脉瘤1例
Pub Date : 2023-06-23 DOI: 10.1177/26324636231173790
Sharath Reddy Annam, Anil Krishna, Amjad Ali
With growing expertise and evolving hardware chronic total occlusion (CTO) percutaneous coronary intervention (PCI) success and safety has been improved remarkably. The nuances of CTO wiring help operators to find novel solutions to the complications created during percutaneous coronary interventions. Accidental coronary perforations caused during CTO interventions can be sealed by wiring from other side and shifting interposing plaque or flap onto perforation. We report a case of saccular aneurysm around the proximal cap formed by antegrade wire escalation in earlier failed percutaneous coronary interventions, which is excluded by “retrograde plaque lift and shift.”
随着专业技术和硬件的不断发展,慢性全闭塞经皮冠状动脉介入治疗(PCI)的成功率和安全性显著提高。CTO接线的细微差别有助于操作员找到新的解决方案,以解决经皮冠状动脉介入治疗期间产生的并发症。在CTO介入期间引起的意外冠状动脉穿孔可以通过从另一侧布线并将中间斑块或皮瓣转移到穿孔上来密封。我们报告一例在早期失败的经皮冠状动脉介入治疗中,由于顺行线扩张而形成的近端冠状动脉周围的囊状动脉瘤,通过“逆行斑块提升和移位”可以排除。
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引用次数: 0
Five Recent Trials That Are Changing Cardiology Practice Across the World 最近的五项试验正在改变全世界的心脏病学实践
Pub Date : 2023-06-01 DOI: 10.1177/26324636231178191
S. Madivada, Angella Patnaik
There are several recent trials that are burgeoning at a rapid pace in the field of cardiology. We picked up 5 trials that impacted our practice: CLEAR OUTCOMES trial, REVIVED BCIS2 trial, DELIVER trial, ADVOR trial, and EBC MAIN trial. After a brief description of the results of these trials, we gave our perspective of their impact on our practice.
最近有几项试验在心脏病学领域迅速发展。我们挑选了5个影响我们实践的试验:CLEAR OUTCOMES试验、救活的BCIS2试验、DELIVER试验、ADVOR试验和EBC MAIN试验。在简要描述了这些试验的结果之后,我们给出了它们对我们实践的影响的观点。
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引用次数: 0
期刊
Indian Journal of Clinical Cardiology
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