As migrant Filipina mothers embark on domestic labor abroad, their children respond in novel and dynamic ways to the work that needs doing within their households. Such work includes caring for siblings and responding to parents’ emotional and marital struggles. This labor emerges from the feminization of the global labor market, which leaves a care slot that young people register and work to fill. Attention to young people’s perspectives on their families and to their enactments of what I call “tender labor” recasts ongoing discussions about care work by highlighting how young people actively participate in the processes of transnational family separation and reunification. A pair of case studies reveals the impact of care extraction in the recesses of domestic life, as children struggle to mitigate the precarity of life for themselves and their loved ones.
{"title":"Tender Labor: Transnational Young People and Continuums of Familial Care","authors":"Jennifer E. Shaw","doi":"10.1111/awr.12186","DOIUrl":"10.1111/awr.12186","url":null,"abstract":"<p>As migrant Filipina mothers embark on domestic labor abroad, their children respond in novel and dynamic ways to the work that needs doing within their households. Such work includes caring for siblings and responding to parents’ emotional and marital struggles. This labor emerges from the feminization of the global labor market, which leaves a care slot that young people register and work to fill. Attention to young people’s perspectives on their families and to their enactments of what I call “tender labor” recasts ongoing discussions about care work by highlighting how young people actively participate in the processes of transnational family separation and reunification. A pair of case studies reveals the impact of care extraction in the recesses of domestic life, as children struggle to mitigate the precarity of life for themselves and their loved ones.</p>","PeriodicalId":43035,"journal":{"name":"Anthropology of Work Review","volume":"41 1","pages":"14-23"},"PeriodicalIF":1.3,"publicationDate":"2020-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/awr.12186","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45956493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
By indexing several key variables in the industry to the “ficha,” the taxi fare multiplier, Buenos Aires’ taxi union recreated economic, fiscal, and legal relations emerging from taxi work. In principle a perfect example of a market device, an actant facilitating economic exchange, the ficha consistently transformed the taxi industry’s income uncertainties into certainties for the union, abstracting its income from wages, contracts, and the amount or value of work. Examining this case study from a political economy approach, I propose the trope of inscription to understand how structural inequalities can be written into the market devices that reproduce them. The political economy approach is a powerful complement to market devices as emergent technologies revolutionize the nature, quality, and management of work in ways shown to reproduce and naturalize hierarchies.
{"title":"Inscription: Taxi Work Relations, the Ficha, and the Political Economy of a Market Device","authors":"Juan Manuel del Nido","doi":"10.1111/awr.12189","DOIUrl":"10.1111/awr.12189","url":null,"abstract":"<p>By indexing several key variables in the industry to the “ficha,” the taxi fare multiplier, Buenos Aires’ taxi union recreated economic, fiscal, and legal relations emerging from taxi work. In principle a perfect example of a market device, an actant facilitating economic exchange, the ficha consistently transformed the taxi industry’s income uncertainties into certainties for the union, abstracting its income from wages, contracts, and the amount or value of work. Examining this case study from a political economy approach, I propose the trope of inscription to understand how structural inequalities can be written into the market devices that reproduce them. The political economy approach is a powerful complement to market devices as emergent technologies revolutionize the nature, quality, and management of work in ways shown to reproduce and naturalize hierarchies.</p>","PeriodicalId":43035,"journal":{"name":"Anthropology of Work Review","volume":"41 1","pages":"50-58"},"PeriodicalIF":1.3,"publicationDate":"2020-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/awr.12189","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42154928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This article focuses on the rise of domestic outsourcing in the high-tech industry in the Galilee in northern Israel. Outsourcing has emerged as a self-proclaimed mode of development targeting Palestinian citizens of Israel. This industry has expanded significantly in the past decade, attracting lucrative funds from public and private sources, and it has received widespread acclaim. Firms in this industry tend to have ties to the Israeli security establishment, a key player in the architecture of high-tech in Israel. At the same time, a Palestinian capitalist class has coalesced around this industry, embracing the discourse of technology and globalization as forms of self-empowerment. I argue that separation—in terms of wages and physical spaces—is a core operational characteristic within this industry, yet firms simultaneously invoke development as part of their organizational cultures, particularly the integration of Palestinian labor into the Israeli economy, empowerment of women, and peacemaking. Locating the practice of domestic outsourcing within a history of subcontracting to the Galilee, I illustrate that this “new” and “innovative” industry builds on established patterns that reinscribe Palestinian workers as a cheaper labor force. These practices illustrate the intertwinement of inclusion and exclusion within neoliberal economic development as well as the mutual production of Palestinians of 1948 as subjects of Israeli capitalism and colonialism.
{"title":"Making Cheaper Labor: Domestic Outsourcing and Development in the Galilee","authors":"Hebatalla Taha","doi":"10.1111/awr.12188","DOIUrl":"10.1111/awr.12188","url":null,"abstract":"<p>This article focuses on the rise of domestic outsourcing in the high-tech industry in the Galilee in northern Israel. Outsourcing has emerged as a self-proclaimed mode of development targeting Palestinian citizens of Israel. This industry has expanded significantly in the past decade, attracting lucrative funds from public and private sources, and it has received widespread acclaim. Firms in this industry tend to have ties to the Israeli security establishment, a key player in the architecture of high-tech in Israel. At the same time, a Palestinian capitalist class has coalesced around this industry, embracing the discourse of technology and globalization as forms of self-empowerment. I argue that separation—in terms of wages and physical spaces—is a core operational characteristic within this industry, yet firms simultaneously invoke development as part of their organizational cultures, particularly the integration of Palestinian labor into the Israeli economy, empowerment of women, and peacemaking. Locating the practice of domestic outsourcing within a history of subcontracting to the Galilee, I illustrate that this “new” and “innovative” industry builds on established patterns that reinscribe Palestinian workers as a cheaper labor force. These practices illustrate the intertwinement of inclusion and exclusion within neoliberal economic development as well as the mutual production of Palestinians of 1948 as subjects of Israeli capitalism and colonialism.</p>","PeriodicalId":43035,"journal":{"name":"Anthropology of Work Review","volume":"41 1","pages":"24-35"},"PeriodicalIF":1.3,"publicationDate":"2020-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/awr.12188","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44009552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Solidarity: Latin America and the United States Left in the Era of Human Rights. Steve Striffler. London: Pluto Press, 2019.","authors":"E. Paul Durrenberger","doi":"10.1111/awr.12184","DOIUrl":"10.1111/awr.12184","url":null,"abstract":"","PeriodicalId":43035,"journal":{"name":"Anthropology of Work Review","volume":"41 1","pages":"61-62"},"PeriodicalIF":1.3,"publicationDate":"2020-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/awr.12184","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46633042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In recent decades, activation has become the paradigm of European social policy. This is a move that many scholars have decried as part of the neoliberalization of the continent's once-robust welfare states. Much of the scholarship on activation, however, has focused on the formal and legal dimensions of policy change, obscuring how activation policies function at the level of everyday life and thus what they actually represent with respect to the broader economic and political shifts remaking contemporary Europe. This article, based on ethnographic fieldwork conducted in Norway between 2015 and 2016, examines one increasingly common activation scheme, the mandatory job-seeker course. While confirming that the courses propagate a neoliberal rhetoric of the “sellable self,” ethnographic evidence contests the notion that this rhetoric is itself evidence of a broader ideological shift within Norway. In fact, the opposite is the case. This rhetoric is not only continuous with a longstanding elite understanding of Norway as an “active society” but also potentially beneficial to the country's universal welfare state. Ultimately, this article argues that insofar as neoliberal rhetoric helps Norway’s unemployed overcome feelings of moral abjection and social disorientation to search for formal, tax-generating employment, it protects rather than undermines the social democratic order.
{"title":"Productive Values: Activating Labor and Finding Selves in Norwegian Job-Seeker Courses","authors":"Kelly McKowen","doi":"10.1111/awr.12192","DOIUrl":"10.1111/awr.12192","url":null,"abstract":"<p>In recent decades, activation has become the paradigm of European social policy. This is a move that many scholars have decried as part of the neoliberalization of the continent's once-robust welfare states. Much of the scholarship on activation, however, has focused on the formal and legal dimensions of policy change, obscuring how activation policies function at the level of everyday life and thus what they actually represent with respect to the broader economic and political shifts remaking contemporary Europe. This article, based on ethnographic fieldwork conducted in Norway between 2015 and 2016, examines one increasingly common activation scheme, the mandatory job-seeker course. While confirming that the courses propagate a neoliberal rhetoric of the “sellable self,” ethnographic evidence contests the notion that this rhetoric is itself evidence of a broader ideological shift within Norway. In fact, the opposite is the case. This rhetoric is not only continuous with a longstanding elite understanding of Norway as an “active society” but also potentially beneficial to the country's universal welfare state. Ultimately, this article argues that insofar as neoliberal rhetoric helps Norway’s unemployed overcome feelings of moral abjection and social disorientation to search for formal, tax-generating employment, it protects rather than undermines the social democratic order.</p>","PeriodicalId":43035,"journal":{"name":"Anthropology of Work Review","volume":"41 1","pages":"3-13"},"PeriodicalIF":1.3,"publicationDate":"2020-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/awr.12192","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47638291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"From Angel to Office Worker: Middle-Class Identity and Female Consciousness in Mexico, 1890–1950. Susie S. Porter. Lincoln: University of Nebraska Press, 2018.","authors":"Evan C. Rothera","doi":"10.1111/awr.12185","DOIUrl":"10.1111/awr.12185","url":null,"abstract":"","PeriodicalId":43035,"journal":{"name":"Anthropology of Work Review","volume":"41 1","pages":"62-64"},"PeriodicalIF":1.3,"publicationDate":"2020-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/awr.12185","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45966338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
There is a growing consensus that emerging forms of flexibilized platform labor (e.g., Upwork, Uber) necessitate new forms of mobilization to resist exploitation, given workers’ atomization and lack of statutory rights. However, Euro-American concerns about radical reductions in labor security are countered by workforces in the “near South,” where precarious, unprotected work has long been the norm. I explore incrementalist organization in motorcycle taxi (ojek) drivers’ resistance to the flexible labor regime of Go-Jek, an Indonesian ride-hailing app. I examine ojek pangkalan (older-style informal-sector drivers) and Himpunan Driver Bandung Raya (HDBR, a grassroots app-based driver association) in the city of Bandung. Although antagonistic toward each other, ojek pangkalan and HDBR employ similar improvisatory strategies, notably micro-territorial basecamps and grassroots social security, to establish claims to their working lives. Incrementalist strategies in Indonesia are thus highly flexible in helping workers manage precarity across formal and informal contexts. By examining organization repertoires among app-based and older-style ojek drivers, this paper contributes to discussions about how the precarity of platform labor is produced and managed in a global context.
越来越多的人认为,鉴于工人的原子化和缺乏法定权利,新兴形式的灵活平台劳动力(例如Upwork、Uber)需要新的动员形式来抵制剥削。然而,欧美对劳动保障急剧减少的担忧,被“近南方”的劳动力所抵消,在那里,不稳定、不受保护的工作长期以来一直是常态。我研究了摩的出租车(ojek)司机对印尼叫车应用Go-Jek灵活的劳动制度的抵制中的渐进主义组织。我研究了万隆市的ojek pangkalan(老式的非正规部门司机)和Himpunan Driver Bandung Raya (HDBR,一个基于应用程序的基层司机协会)。虽然彼此对立,但ojek pangkalan和HDBR采用了类似的即兴策略,特别是微观领土基地营地和基层社会保障,以建立对其工作生活的要求。因此,印度尼西亚的渐进主义战略在帮助工人在正式和非正式环境中管理不稳定方面具有高度的灵活性。通过检查基于应用程序和老式ojek司机之间的组织库,本文有助于讨论如何在全球背景下产生和管理平台劳动力的不稳定性。
{"title":"Platform Labor and In/Formality: Organization among Motorcycle Taxi Drivers in Bandung, Indonesia","authors":"Bronwyn Frey","doi":"10.1111/awr.12187","DOIUrl":"10.1111/awr.12187","url":null,"abstract":"<p>There is a growing consensus that emerging forms of flexibilized platform labor (e.g., Upwork, Uber) necessitate new forms of mobilization to resist exploitation, given workers’ atomization and lack of statutory rights. However, Euro-American concerns about radical reductions in labor security are countered by workforces in the “near South,” where precarious, unprotected work has long been the norm. I explore incrementalist organization in motorcycle taxi (<i>ojek</i>) drivers’ resistance to the flexible labor regime of Go-Jek, an Indonesian ride-hailing app. I examine <i>ojek pangkalan</i> (older-style informal-sector drivers) and Himpunan Driver Bandung Raya (HDBR, a grassroots app-based driver association) in the city of Bandung. Although antagonistic toward each other, ojek pangkalan and HDBR employ similar improvisatory strategies, notably micro-territorial basecamps and grassroots social security, to establish claims to their working lives. Incrementalist strategies in Indonesia are thus highly flexible in helping workers manage precarity across formal and informal contexts. By examining organization repertoires among app-based and older-style ojek drivers, this paper contributes to discussions about how the precarity of platform labor is produced and managed in a global context.</p>","PeriodicalId":43035,"journal":{"name":"Anthropology of Work Review","volume":"41 1","pages":"36-49"},"PeriodicalIF":1.3,"publicationDate":"2020-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/awr.12187","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43027335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Choke Points: Logistics Workers Disrupting the Global Supply Chain. Edited by Jake Alimahomed-Wilson and Immanuel Ness. London: Pluto Press, 2018.","authors":"Kate Crane","doi":"10.1111/awr.12190","DOIUrl":"10.1111/awr.12190","url":null,"abstract":"","PeriodicalId":43035,"journal":{"name":"Anthropology of Work Review","volume":"41 1","pages":"59-60"},"PeriodicalIF":1.3,"publicationDate":"2020-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/awr.12190","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47320725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Review Essay","authors":"Christine Hegel","doi":"10.1111/awr.12191","DOIUrl":"10.1111/awr.12191","url":null,"abstract":"","PeriodicalId":43035,"journal":{"name":"Anthropology of Work Review","volume":"41 1","pages":"65-68"},"PeriodicalIF":1.3,"publicationDate":"2020-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/awr.12191","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44002367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-04-01Epub Date: 2019-10-31DOI: 10.1089/jamp.2019.1547
Dik Ng, Edward M Kerwin, Martha V White, S David Miller, Scott Haughie, Jonathan K Ward, Richard Allan
Background: Wixela® Inhub® is a dry powder inhaler approved as a generic equivalent to Advair® Diskus® (fluticasone propionate [FP]/salmeterol fixed-dose combination) for patients with asthma or chronic obstructive pulmonary disease (COPD). This study aimed at confirming the local (lung) therapeutic equivalence of both the FP and salmeterol components of Wixela Inhub (test [T]) to Advair Diskus (reference [R]) after inhalation. Methods: This randomized, double-blind, double-dummy, placebo-controlled, parallel-group study in patients ≥18 years with mild-to-moderate persistent asthma compared the local therapeutic equivalence (using forced expiratory volume in 1 second [FEV1]) of FP/salmeterol (100/50 μg) after inhaled delivery via T and R. Results: Randomized patients (N = 1127) received T (n = 512), R (n = 512), or placebo (n = 103). T and R significantly increased day 1 FEV1 area under the effect curve over 12 hours of the change from baseline (AUC[0-12]) and day 29 trough FEV1 over placebo, indicating that these endpoints were sufficiently sensitive for evaluation of bioequivalence. On day 1, T and R each increased FEV1 AUC(0-12) over placebo (3.134 L•h [T], 2.677 L•h [R]; each p < 0.0001). Following twice-daily dosing for 28 days, T and R also each increased trough FEV1 (measured on day 29) over placebo (235 mL [T], 215 mL [R]; each p < 0.0001). Least-squares mean T/R ratios (90% confidence intervals) for day 1 FEV1 AUC(0-12) and day 29 trough FEV1 were 1.120 (1.016-1.237) and 1.069 (0.938-1.220), respectively, indicating that T and R were bioequivalent for both co-primary endpoints. FP/salmeterol was well tolerated when administered via either T or R. Conclusions: These results demonstrate that the therapeutic effects of Wixela Inhub are bioequivalent to Advair Diskus in the lung. Wixela Inhub represents a therapeutically equivalent new FP/salmeterol treatment option for use in the treatment of asthma and COPD.
背景:Wixela® Inhub®是一种干粉吸入器,已被批准作为Advair® Diskus®(丙酸氟替卡松[FP]/沙美特罗固定剂量复方制剂)的等效仿制药,用于哮喘或慢性阻塞性肺病(COPD)患者。本研究旨在确认吸入 Wixela Inhub(测试 [T])后,FP 和沙美特罗成分与 Advair Diskus(参考 [R])的局部(肺部)治疗等效性。研究方法这项随机、双盲、双哑剂、安慰剂对照、平行组研究针对年龄≥18 岁的轻度至中度持续性哮喘患者,比较了通过 T 和 R 吸入后 FP/沙美特罗(100/50 μg)的局部治疗等效性(使用 1 秒用力呼气容积 [FEV1]):随机患者(1127 人)接受了 T(512 人)、R(512 人)或安慰剂(103 人)。与安慰剂相比,T 和 R 能明显增加第 1 天 FEV1 从基线开始变化 12 小时的效应曲线下面积(AUC[0-12])和第 29 天谷值 FEV1,表明这些终点对评估生物等效性足够敏感。在第 1 天,T 和 R 的 FEV1 AUC(0-12) 均比安慰剂高(3.134 L-h [T],2.677 L-h [R];各 p 1(在第 29 天测量),比安慰剂高(235 mL [T],215 mL [R];各 p 1 AUC(0-12) 和第 29 天谷值 FEV1 分别为 1.016-1.120 (1.016-1.016-1.120) mL)。120 (1.016-1.237) 和 1.069 (0.938-1.220),这表明 T 和 R 在两个共同主要终点上具有生物等效性。通过 T 或 R 给药时,FP/沙美特罗的耐受性良好:这些结果表明,Wixela Inhub 在肺部的治疗效果与Advair Diskus 具有生物等效性。Wixela Inhub是治疗哮喘和慢性阻塞性肺病的一种治疗效果等效的新型FP/沙美特罗治疗方案。
{"title":"Clinical Bioequivalence of Wixela Inhub and Advair Diskus in Adults With Asthma.","authors":"Dik Ng, Edward M Kerwin, Martha V White, S David Miller, Scott Haughie, Jonathan K Ward, Richard Allan","doi":"10.1089/jamp.2019.1547","DOIUrl":"10.1089/jamp.2019.1547","url":null,"abstract":"<p><p><b><i>Background:</i></b> Wixela<sup>®</sup> Inhub<sup>®</sup> is a dry powder inhaler approved as a generic equivalent to Advair<sup>®</sup> Diskus<sup>®</sup> (fluticasone propionate [FP]/salmeterol fixed-dose combination) for patients with asthma or chronic obstructive pulmonary disease (COPD). This study aimed at confirming the local (lung) therapeutic equivalence of both the FP and salmeterol components of Wixela Inhub (test [T]) to Advair Diskus (reference [R]) after inhalation. <b><i>Methods:</i></b> This randomized, double-blind, double-dummy, placebo-controlled, parallel-group study in patients ≥18 years with mild-to-moderate persistent asthma compared the local therapeutic equivalence (using forced expiratory volume in 1 second [FEV<sub>1</sub>]) of FP/salmeterol (100/50 μg) after inhaled delivery via T and R. <b><i>Results:</i></b> Randomized patients (<i>N</i> = 1127) received T (<i>n</i> = 512), R (<i>n</i> = 512), or placebo (<i>n</i> = 103). T and R significantly increased day 1 FEV<sub>1</sub> area under the effect curve over 12 hours of the change from baseline (AUC<sub>[0-12]</sub>) and day 29 trough FEV<sub>1</sub> over placebo, indicating that these endpoints were sufficiently sensitive for evaluation of bioequivalence. On day 1, T and R each increased FEV<sub>1</sub> AUC<sub>(0-12)</sub> over placebo (3.134 L•h [T], 2.677 L•h [R]; each <i>p</i> < 0.0001). Following twice-daily dosing for 28 days, T and R also each increased trough FEV<sub>1</sub> (measured on day 29) over placebo (235 mL [T], 215 mL [R]; each <i>p</i> < 0.0001). Least-squares mean T/R ratios (90% confidence intervals) for day 1 FEV<sub>1</sub> AUC<sub>(0-12)</sub> and day 29 trough FEV<sub>1</sub> were 1.120 (1.016-1.237) and 1.069 (0.938-1.220), respectively, indicating that T and R were bioequivalent for both co-primary endpoints. FP/salmeterol was well tolerated when administered via either T or R. <b><i>Conclusions:</i></b> These results demonstrate that the therapeutic effects of Wixela Inhub are bioequivalent to Advair Diskus in the lung. Wixela Inhub represents a therapeutically equivalent new FP/salmeterol treatment option for use in the treatment of asthma and COPD.</p>","PeriodicalId":43035,"journal":{"name":"Anthropology of Work Review","volume":"32 1","pages":"99-107"},"PeriodicalIF":3.4,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7133441/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85297569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}