Pub Date : 2023-08-01DOI: 10.15825/1995-1191-2023-3-8-30
S. V. Gautier, S. M. Khomyakov
Objective : to monitor the current trends and developments in organ donation and transplantation in the Russian Federation based on data from the year 2022. Materials and methods . Heads of organ transplant centers were surveyed through questionnaires. Data control was done using the information accounting system of the Russian Ministry of Health. We performed a comparative analysis of data obtained over years from various federal subjects of the Russian Federation and transplant centers. Results . Based on data retrieved from the National Registry in 2022, 46 kidney, 31 liver and 16 heart transplant programs were existing in the Russian Federation as of the year 2022. Organ donation activity in 2022 was 5.2 per million population (p.m.p.), with a 73.7% multi-organ procurement rate and an average of 2.8 organs procured from one effective donor. In 2022, 2,555 organ transplants were performed in the Russian Federation, which included 1,562 kidney, 659 liver and 310 heart transplants. Same year, the number of transplant surgeries performed in the Russian Federation increased by 10.0% compared to 2021. In Moscow, organ donation activity was 26.3 p.m.p. The city of Moscow and the Moscow Oblast alone had a total of 12 transplant centers, accounting for 52.6% of all kidney transplants and 64.8% of all extrarenal transplants in the country. The number of organ recipients in the Russian Federation exceeds 150 p.m.p. Conclusion . The geographic distribution of transplant centers in the Russian Federation continues to expand. Five new centers were opened in 2022. Over the past year, the number of effective donors and organ transplants increased in the country. The resource potential of medical institutions has not been exhausted and this is set to further increase the number of organ transplants performed. Moscow is the powerhouse of Russian transplantology. However, other regional leaders have since appeared in the Russian Federation, such as in Kemerovo, Kazan, Rostov-on-Don, Tyumen, Irkutsk, and Volzhsky. In the Russian Federation, priority is being given to pediatric transplant care. It is expedient to implement a complex of measures aimed at identifying potential recipients.
{"title":"Organ donation and transplantation in the Russian Federation in 2022. 15<sup>th</sup> Report from the Registry of the Russian Transplant Society","authors":"S. V. Gautier, S. M. Khomyakov","doi":"10.15825/1995-1191-2023-3-8-30","DOIUrl":"https://doi.org/10.15825/1995-1191-2023-3-8-30","url":null,"abstract":"Objective : to monitor the current trends and developments in organ donation and transplantation in the Russian Federation based on data from the year 2022. Materials and methods . Heads of organ transplant centers were surveyed through questionnaires. Data control was done using the information accounting system of the Russian Ministry of Health. We performed a comparative analysis of data obtained over years from various federal subjects of the Russian Federation and transplant centers. Results . Based on data retrieved from the National Registry in 2022, 46 kidney, 31 liver and 16 heart transplant programs were existing in the Russian Federation as of the year 2022. Organ donation activity in 2022 was 5.2 per million population (p.m.p.), with a 73.7% multi-organ procurement rate and an average of 2.8 organs procured from one effective donor. In 2022, 2,555 organ transplants were performed in the Russian Federation, which included 1,562 kidney, 659 liver and 310 heart transplants. Same year, the number of transplant surgeries performed in the Russian Federation increased by 10.0% compared to 2021. In Moscow, organ donation activity was 26.3 p.m.p. The city of Moscow and the Moscow Oblast alone had a total of 12 transplant centers, accounting for 52.6% of all kidney transplants and 64.8% of all extrarenal transplants in the country. The number of organ recipients in the Russian Federation exceeds 150 p.m.p. Conclusion . The geographic distribution of transplant centers in the Russian Federation continues to expand. Five new centers were opened in 2022. Over the past year, the number of effective donors and organ transplants increased in the country. The resource potential of medical institutions has not been exhausted and this is set to further increase the number of organ transplants performed. Moscow is the powerhouse of Russian transplantology. However, other regional leaders have since appeared in the Russian Federation, such as in Kemerovo, Kazan, Rostov-on-Don, Tyumen, Irkutsk, and Volzhsky. In the Russian Federation, priority is being given to pediatric transplant care. It is expedient to implement a complex of measures aimed at identifying potential recipients.","PeriodicalId":43091,"journal":{"name":"Vestnik Transplantologii i Iskusstvennyh Organov","volume":"70 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134996800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-28DOI: 10.15825/1995-1191-2023-3-106-112
O. Yu. Esipova, V. K. Bogdanov, A. S. Esipov, A. P. Kuleshov, A. S. Buchnev, E. A. Volkova, A. A. Drobyshev, N. V. Grudinin
Small animal models are widely used in basic research. However, experimental hydrodynamic test benches, which include extracorporeal circuits, often have limitations associated with the size and filling volume of equipment. Thus, we aimed at developing and validating a miniature oxygenator as well as a low-volume hydrodynamic system for ex vivo perfusion of small animal lungs. A series of low-volume membrane oxygenators (n = 10) with 90–100 aligned microporous polypropylene hollow fibers, placed inside a sheath that is sealed at both ends to isolate the perfusing solution, was designed and manufactured. This design makes gas to flow through the hollow fibers and perfusate to circulate around the fibers. A low-volume hydrodynamic test bench was designed and assembled for isolated ex vivo lung perfusion and for evaluation of the performance characteristics of the oxygenators: gas and perfusate flow, perfusion pressure and temperature at 5–70 ml/min flow range.
{"title":"Development of a new low-volume oxygenator and creation of a hydrodynamic test bench for ex vivo lung perfusion in small animals","authors":"O. Yu. Esipova, V. K. Bogdanov, A. S. Esipov, A. P. Kuleshov, A. S. Buchnev, E. A. Volkova, A. A. Drobyshev, N. V. Grudinin","doi":"10.15825/1995-1191-2023-3-106-112","DOIUrl":"https://doi.org/10.15825/1995-1191-2023-3-106-112","url":null,"abstract":"Small animal models are widely used in basic research. However, experimental hydrodynamic test benches, which include extracorporeal circuits, often have limitations associated with the size and filling volume of equipment. Thus, we aimed at developing and validating a miniature oxygenator as well as a low-volume hydrodynamic system for ex vivo perfusion of small animal lungs. A series of low-volume membrane oxygenators (n = 10) with 90–100 aligned microporous polypropylene hollow fibers, placed inside a sheath that is sealed at both ends to isolate the perfusing solution, was designed and manufactured. This design makes gas to flow through the hollow fibers and perfusate to circulate around the fibers. A low-volume hydrodynamic test bench was designed and assembled for isolated ex vivo lung perfusion and for evaluation of the performance characteristics of the oxygenators: gas and perfusate flow, perfusion pressure and temperature at 5–70 ml/min flow range.","PeriodicalId":43091,"journal":{"name":"Vestnik Transplantologii i Iskusstvennyh Organov","volume":"146 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135355233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-20DOI: 10.15825/1995-1191-2023-3-97-105
A. N. Shutko, O. A. Gerasimova, N. V. Marchenko, I. I. Tileubergenov
Objective : to study the applicability of the neutrophil-to-lymphocyte ratio (NLR) for monitoring recipient status and for possible minimization of maintenance immunosuppression in the long-term period after liver transplantation (LT). Materials and methods . Blood samples of 19 recipients with satisfactory graft function were examined by flow cytofluorometry at various time periods after LT using hematopoietic stem cell markers CD133, their CD31 derivatives, and alpha-fetoprotein (AFP), compared with the conventional NLR. Results . The use of NLR equivalents with CD133 and CD31 to assess liver transplant status is due to their high representation in liver tissue. Their values change in the long-term posttransplant period (from 1.5 to 6–7 years following LT) ≈20-fold and in different directions, but only when measuring their commissural to the liver cell fractions bearing the AFP marker. Conclusion . In contrast to the conventional NLR, maintenance of the lowest level of CD31 AFP, an NLR «equivalent», achieved at 1.5 years after LT, can be considered a criterion for the success of immunosuppressive therapy in the long-term post-LT period. The developed technique can be used to decide on whether to reduce or discontinue medication-assisted prophylaxis of graft rejection.
{"title":"Equivalents of the neutrophil-to-lymphocyte ratio of circulating pool of stem and immature hematopoietic cells for assessing liver transplant status","authors":"A. N. Shutko, O. A. Gerasimova, N. V. Marchenko, I. I. Tileubergenov","doi":"10.15825/1995-1191-2023-3-97-105","DOIUrl":"https://doi.org/10.15825/1995-1191-2023-3-97-105","url":null,"abstract":"Objective : to study the applicability of the neutrophil-to-lymphocyte ratio (NLR) for monitoring recipient status and for possible minimization of maintenance immunosuppression in the long-term period after liver transplantation (LT). Materials and methods . Blood samples of 19 recipients with satisfactory graft function were examined by flow cytofluorometry at various time periods after LT using hematopoietic stem cell markers CD133, their CD31 derivatives, and alpha-fetoprotein (AFP), compared with the conventional NLR. Results . The use of NLR equivalents with CD133 and CD31 to assess liver transplant status is due to their high representation in liver tissue. Their values change in the long-term posttransplant period (from 1.5 to 6–7 years following LT) ≈20-fold and in different directions, but only when measuring their commissural to the liver cell fractions bearing the AFP marker. Conclusion . In contrast to the conventional NLR, maintenance of the lowest level of CD31 AFP, an NLR «equivalent», achieved at 1.5 years after LT, can be considered a criterion for the success of immunosuppressive therapy in the long-term post-LT period. The developed technique can be used to decide on whether to reduce or discontinue medication-assisted prophylaxis of graft rejection.","PeriodicalId":43091,"journal":{"name":"Vestnik Transplantologii i Iskusstvennyh Organov","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135237645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-05DOI: 10.15825/1995-1191-2023-3-64-67
D. A. Sirota, M. O. Zhulkov, A. G. Makaev, D. S. Khvan, D. V. Doronin, K. A. Agaeva, A. V. Fomichev, A. M. Chernyavsky
Cardiac injury remains one of the most complex conditions in emergency surgery. Only 6% of patients with penetrating heart wounds manage to be delivered to the operating room for surgery, and the mortality rate is still extremely high. Unfortunately, such emergency interventions are often performed in institutions lacking the ability to provide the full range of reconstructive techniques, resulting in suboptimal correction and a high risk of developing postoperative complications. This paper describes a clinical case of successful repair of multiple stab wounds to the heart with concomitant anterior descending artery injury followed by severe heart failure requiring biventricular mechanical circulatory support.
{"title":"Clinical case of long-term mechanical circulatory support in a patient with biventricular heart failure after cardiac stab wound","authors":"D. A. Sirota, M. O. Zhulkov, A. G. Makaev, D. S. Khvan, D. V. Doronin, K. A. Agaeva, A. V. Fomichev, A. M. Chernyavsky","doi":"10.15825/1995-1191-2023-3-64-67","DOIUrl":"https://doi.org/10.15825/1995-1191-2023-3-64-67","url":null,"abstract":"Cardiac injury remains one of the most complex conditions in emergency surgery. Only 6% of patients with penetrating heart wounds manage to be delivered to the operating room for surgery, and the mortality rate is still extremely high. Unfortunately, such emergency interventions are often performed in institutions lacking the ability to provide the full range of reconstructive techniques, resulting in suboptimal correction and a high risk of developing postoperative complications. This paper describes a clinical case of successful repair of multiple stab wounds to the heart with concomitant anterior descending artery injury followed by severe heart failure requiring biventricular mechanical circulatory support.","PeriodicalId":43091,"journal":{"name":"Vestnik Transplantologii i Iskusstvennyh Organov","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135752759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-05DOI: 10.15825/1995-1191-2023-3-76-86
A. D. Kirillova, E. A. Nemets, A. M. Grigoriev, L. A. Kirsanova, V. A. Ryzhikova, E. A. Volkova, Yu. B. Basok, V. I. Sevastianov
Objective : to study the effect of trypsin pretreatment in the porcine articular cartilage decellularization protocol on the ability to restore the biochemical composition and functional properties of the resulting finely dispersed tissue-specific scaffold when co-cultured with human adipose-derived stem cells (hADSCs). Materials and methods . Porcine articular cartilage was micronized to a maximum size of 250 μm. The resulting porcine articular cartilage microparticles (CMps) were treated with trypsin (0.05, 0.25, 0.50%) / EDTA solution at +37 °C for 24 hours. Then, the CMps were successively incubated for 24 hours in three surfactant solutions containing 0.1% sodium dodecyl sulfate and increasing concentration of Triton X-100 (1, 2, 3%) at room temperature and in DNase I solution at +37 °C for 48 hours. The degree of change in the biochemical composition and the ability of decellularized CMps (DCMps) scaffolds within cell-engineered constructs (CECs) to support hADSC adhesion and proliferation, as well as their potential ability to exert a stimulatory regenerative effect, were then assessed. DNA, glycosaminoglycans (GAGs) and collagen content in the DCMps and CECs were examined. The morphology of the samples was examined using histological and immunohistochemistry staining. Results . Histological analysis showed that there were no cells and detritus in the DCMp samples. Pretreatment of CMps samples гыштп a solution with the lowest content of trypsin (0.05%) / EDTA in the samples retained 5.14 ± 0.87 ng/mg DNA in the samples, while GAG content decreased to 5.34 ± 0.9 μg/mg and collagen to 154 ± 34 μg/mg. By day 28 of CEC cultivation, adherent cells had produced their own extracellular matrix (ECM) containing GAGs and collagen. The amount of DNA in it was 6.30 ± 0.11 μg/CEC and that of GAGs was 19.36 ± 0.73 μg/CEC. Conclusion . Pretreatment with trypsin allows achieving uniformly complete decellularized CMps. At the same time, onset of changes in the ECM composition indicates a decrease in the ability of hADSCs to synthesize GAGs and type II collagen during co-culturing with DCMps. The increased proliferative activity of adherent hADSCs, as well as the tissue specificity of the DCMp scaffold will allow further research towards a hydrogel matrix capable of enhancing the specific and stimulating regenerative potential when co-cultured with cells of the same phenotype.
{"title":"Effect of trypsin on biochemical and functional properties of decellularized porcine articular cartilage","authors":"A. D. Kirillova, E. A. Nemets, A. M. Grigoriev, L. A. Kirsanova, V. A. Ryzhikova, E. A. Volkova, Yu. B. Basok, V. I. Sevastianov","doi":"10.15825/1995-1191-2023-3-76-86","DOIUrl":"https://doi.org/10.15825/1995-1191-2023-3-76-86","url":null,"abstract":"Objective : to study the effect of trypsin pretreatment in the porcine articular cartilage decellularization protocol on the ability to restore the biochemical composition and functional properties of the resulting finely dispersed tissue-specific scaffold when co-cultured with human adipose-derived stem cells (hADSCs). Materials and methods . Porcine articular cartilage was micronized to a maximum size of 250 μm. The resulting porcine articular cartilage microparticles (CMps) were treated with trypsin (0.05, 0.25, 0.50%) / EDTA solution at +37 °C for 24 hours. Then, the CMps were successively incubated for 24 hours in three surfactant solutions containing 0.1% sodium dodecyl sulfate and increasing concentration of Triton X-100 (1, 2, 3%) at room temperature and in DNase I solution at +37 °C for 48 hours. The degree of change in the biochemical composition and the ability of decellularized CMps (DCMps) scaffolds within cell-engineered constructs (CECs) to support hADSC adhesion and proliferation, as well as their potential ability to exert a stimulatory regenerative effect, were then assessed. DNA, glycosaminoglycans (GAGs) and collagen content in the DCMps and CECs were examined. The morphology of the samples was examined using histological and immunohistochemistry staining. Results . Histological analysis showed that there were no cells and detritus in the DCMp samples. Pretreatment of CMps samples гыштп a solution with the lowest content of trypsin (0.05%) / EDTA in the samples retained 5.14 ± 0.87 ng/mg DNA in the samples, while GAG content decreased to 5.34 ± 0.9 μg/mg and collagen to 154 ± 34 μg/mg. By day 28 of CEC cultivation, adherent cells had produced their own extracellular matrix (ECM) containing GAGs and collagen. The amount of DNA in it was 6.30 ± 0.11 μg/CEC and that of GAGs was 19.36 ± 0.73 μg/CEC. Conclusion . Pretreatment with trypsin allows achieving uniformly complete decellularized CMps. At the same time, onset of changes in the ECM composition indicates a decrease in the ability of hADSCs to synthesize GAGs and type II collagen during co-culturing with DCMps. The increased proliferative activity of adherent hADSCs, as well as the tissue specificity of the DCMp scaffold will allow further research towards a hydrogel matrix capable of enhancing the specific and stimulating regenerative potential when co-cultured with cells of the same phenotype.","PeriodicalId":43091,"journal":{"name":"Vestnik Transplantologii i Iskusstvennyh Organov","volume":"252 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135752757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-05DOI: 10.15825/1995-1191-2023-3-57-63
S. V. Popov, R. G. Huseynov, I. A. Miloserdov, Yu. V. Kisil, D. A. Saydulaev, S. V. Sadovnikov, K. V. Sivak, N. S. Bunenkov, V. V. Perepelitsa, T. A. Lelyavina
Nephrolithiasis in a transplanted kidney is an important medical and social problem. The presence of renal calculi may not manifest clinically for a long time due to the peculiarities of the surgical intervention during organ transplantation. Development of chronic urinary tract infection and deterioration of the functional ability of the renal transplant in the presence of kidney stones can lead to graft death, which is an immediate threat to the patient’s life. Existing Russian guidelines on the treatment of urolithiasis currently lack a clear strategy for the management of kidney transplant recipients. Objective : to systematize literature data on analysis of the outcomes of extracorporeal shock wave lithotripsy (ESWL) and other methods in patients with post-transplant kidney stones. Results . Thirty-five publications on the research topic were selected. We summarized the information on various therapy options for patients with stones in transplanted kidney: endourological approach, ESWL, percutaneous nephrolithotripsy (PCNL), open surgical treatment (nephrostomy, pyelolithotomy). A modern foreign algorithm for the management of patients with post-transplant kidney stones depending on the severity of obstruction with sepsis and the size of the renal calculi is presented. Conclusion . 1. The presence of stones in a kidney graft is a clinical situation that requires surgical treatment. 2. In clinical practice, different methods of treatment can be used, such as open intervention, ESWL, PCNL, retrograde transurethral manipulations. 3. In most cases, patient management tactics depend on the clinical picture (presence/absence of obstruction) and the size of the calculi. 4. The use of ESWL, as the most frequently used method, testifies to its efficiency and low-traumatic effect.
{"title":"Efficacy of extracorporeal shock wave lithotripsy for post-transplant kidney stones. Hope or Disappointment?","authors":"S. V. Popov, R. G. Huseynov, I. A. Miloserdov, Yu. V. Kisil, D. A. Saydulaev, S. V. Sadovnikov, K. V. Sivak, N. S. Bunenkov, V. V. Perepelitsa, T. A. Lelyavina","doi":"10.15825/1995-1191-2023-3-57-63","DOIUrl":"https://doi.org/10.15825/1995-1191-2023-3-57-63","url":null,"abstract":"Nephrolithiasis in a transplanted kidney is an important medical and social problem. The presence of renal calculi may not manifest clinically for a long time due to the peculiarities of the surgical intervention during organ transplantation. Development of chronic urinary tract infection and deterioration of the functional ability of the renal transplant in the presence of kidney stones can lead to graft death, which is an immediate threat to the patient’s life. Existing Russian guidelines on the treatment of urolithiasis currently lack a clear strategy for the management of kidney transplant recipients. Objective : to systematize literature data on analysis of the outcomes of extracorporeal shock wave lithotripsy (ESWL) and other methods in patients with post-transplant kidney stones. Results . Thirty-five publications on the research topic were selected. We summarized the information on various therapy options for patients with stones in transplanted kidney: endourological approach, ESWL, percutaneous nephrolithotripsy (PCNL), open surgical treatment (nephrostomy, pyelolithotomy). A modern foreign algorithm for the management of patients with post-transplant kidney stones depending on the severity of obstruction with sepsis and the size of the renal calculi is presented. Conclusion . 1. The presence of stones in a kidney graft is a clinical situation that requires surgical treatment. 2. In clinical practice, different methods of treatment can be used, such as open intervention, ESWL, PCNL, retrograde transurethral manipulations. 3. In most cases, patient management tactics depend on the clinical picture (presence/absence of obstruction) and the size of the calculi. 4. The use of ESWL, as the most frequently used method, testifies to its efficiency and low-traumatic effect.","PeriodicalId":43091,"journal":{"name":"Vestnik Transplantologii i Iskusstvennyh Organov","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135752758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2014-06-24DOI: 10.15825/1995-1191-2013-3-92-101
Array В. Готье, Array П. Иткин, Array Ю. Шемакин, Array Ш. Саитгареев, Array Н. Попцов, A. M. Захаревич, Array А. Акопов, Array Я. Кормер, Array А. Халилулин, A. Шевченко, Array М. Невзоров, Array А. Филатов, Array В. Селищев
The paper describes the fi rst clinical experience in RF of successful application of domestic circulatory support device based on implantable axial pump for two stage heart transplantation. This case demonstrate the effec- tiveness and safety of our device ( АВК - Н ) for a longtime (270 days) left ventricular bypass and the ability to perform a successful transplantation of donor , s heart after application of this system.
{"title":"ПЕРВЫЙ ОПЫТ КЛИНИЧЕСКОГО ПРИМЕНЕНИЯ ОТЕЧЕСТВЕННОГО АППАРАТА ВСПОМОГАТЕЛЬНОГО КРОВООБРАЩЕНИЯ НА БАЗЕ ИМПЛАНТИРУЕМОГО ОСЕВОГО НАСОСА ДЛЯ ДВУХЭТАПНОЙ ТРАНСПЛАНТАЦИИ СЕРДЦА","authors":"Array В. Готье, Array П. Иткин, Array Ю. Шемакин, Array Ш. Саитгареев, Array Н. Попцов, A. M. Захаревич, Array А. Акопов, Array Я. Кормер, Array А. Халилулин, A. Шевченко, Array М. Невзоров, Array А. Филатов, Array В. Селищев","doi":"10.15825/1995-1191-2013-3-92-101","DOIUrl":"https://doi.org/10.15825/1995-1191-2013-3-92-101","url":null,"abstract":"The paper describes the fi rst clinical experience in RF of successful application of domestic circulatory support device based on implantable axial pump for two stage heart transplantation. This case demonstrate the effec- tiveness and safety of our device ( АВК - Н ) for a longtime (270 days) left ventricular bypass and the ability to perform a successful transplantation of donor , s heart after application of this system.","PeriodicalId":43091,"journal":{"name":"Vestnik Transplantologii i Iskusstvennyh Organov","volume":"15 1","pages":"92-101"},"PeriodicalIF":0.2,"publicationDate":"2014-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67245669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2014-06-16DOI: 10.15825/1995-1191-2011-2-87-94
В. Е. Загайнов, Александр Александрович Серегин, А. И. Зайцев, В. А. Бельский, П. И. Рыхтик, Н. В. Заречнова, С. А. Васенин, Е. Н. Рябова, Г. Г. Горохов, Л. В. Шкалова
Splenic artery steal syndrome is one of possible arterial complications after orthotopic liver transplantation. Material includes personal experience in diagnostics and treatment of this syndrome. In each case complication was opportunely suspected basing on laboratory and ultrasound data and proved by angiography. Successful treatment was performed using different variants of splenic artery embolization.
{"title":"«СИНДРОМ ОБКРАДЫВАНИЯ» СЕЛЕЗЕНОЧНОЙ АРТЕРИЕЙ ПОСЛЕ ОРТОТОПИЧЕСКОЙ ТРАНСПЛАНТАЦИИ ПЕЧЕНИ","authors":"В. Е. Загайнов, Александр Александрович Серегин, А. И. Зайцев, В. А. Бельский, П. И. Рыхтик, Н. В. Заречнова, С. А. Васенин, Е. Н. Рябова, Г. Г. Горохов, Л. В. Шкалова","doi":"10.15825/1995-1191-2011-2-87-94","DOIUrl":"https://doi.org/10.15825/1995-1191-2011-2-87-94","url":null,"abstract":"Splenic artery steal syndrome is one of possible arterial complications after orthotopic liver transplantation. Material includes personal experience in diagnostics and treatment of this syndrome. In each case complication was opportunely suspected basing on laboratory and ultrasound data and proved by angiography. Successful treatment was performed using different variants of splenic artery embolization.","PeriodicalId":43091,"journal":{"name":"Vestnik Transplantologii i Iskusstvennyh Organov","volume":"13 1","pages":"87-94"},"PeriodicalIF":0.2,"publicationDate":"2014-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67245205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2014-06-09DOI: 10.15825/1995-1191-2011-1-100-107
И. В. Логинова, Н. В. Кечаева, Олег Николаевич Резник
This review highlights the main problem in organ donation practice. There was done the analysis of main orga- nizational solutions and best organ donation policy practices with accent on Spain Model of organ donation, and the comparing U.S. organ donation system. Last «break through» international initiatives for improving organ donation practice were brought from WHA and WHO resolutions.
{"title":"IMPORTANCE OF ORGANIZATIONAL FACTORS IN OVERCOMING THE SHORTAGE OF DONOR ORGANS","authors":"И. В. Логинова, Н. В. Кечаева, Олег Николаевич Резник","doi":"10.15825/1995-1191-2011-1-100-107","DOIUrl":"https://doi.org/10.15825/1995-1191-2011-1-100-107","url":null,"abstract":"This review highlights the main problem in organ donation practice. There was done the analysis of main orga- nizational solutions and best organ donation policy practices with accent on Spain Model of organ donation, and the comparing U.S. organ donation system. Last «break through» international initiatives for improving organ donation practice were brought from WHA and WHO resolutions.","PeriodicalId":43091,"journal":{"name":"Vestnik Transplantologii i Iskusstvennyh Organov","volume":"13 1","pages":"100-107"},"PeriodicalIF":0.2,"publicationDate":"2014-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67245110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2014-06-05DOI: 10.15825/1995-1191-2010-1-51-55
I. Yermakova, V. P. Buzulina, I. E. Borodulin, I. A. Pronchenko, Tomilina Na
The dependence between minute calcium and sodium excretion from 1 L glomerular fi ltrate (CaE/GFR; NaE/GFR) with NaE/GFR from 0,1 to 9,71 mmol/l GFR was studied in 103 health volunteers. There was received asymptotique curve with r 2 = 0,54; Y = 0,06 [1 – exp (–x/2,34)]. The nomogramm with con fi dence intervals of 95% was built. On the basis of renal physiology it was offered differentiate gradual (to electrochemical gradiate created by sodium reabsorbtion) and active calcium reabsorbtion. It was assumed that gradual calcium reabsorbtion is equel to sodium reabsorbtion and may be estimate by NaE/GFR, CNa/GFR. We considered that active calcium reabsorbtion is normal if the correlation between CaE/GFR and NaE/GFR is inside being decreased if the correlation is higher and increased if the correlation is lower probable intervals. We proposed T-score CaE/GFR as the quantative parameter of active calcium reabsorbtion. It varied in health volunteers from –1,74 to +2,15. The method was applied in 236 recipients of allotransplanted kidney.
{"title":"РАЗРАБОТКА МЕТОДА ОПРЕДЕЛЕНИЯ ГРАДИЕНТНОЙ И АКТИВНОЙ РЕАБСОРБЦИИ КАЛЬЦИЯ ДЛЯ ОЦЕНКИ ФУНКЦИИ ПЕРЕСАЖЕННОЙ ПОЧКИ","authors":"I. Yermakova, V. P. Buzulina, I. E. Borodulin, I. A. Pronchenko, Tomilina Na","doi":"10.15825/1995-1191-2010-1-51-55","DOIUrl":"https://doi.org/10.15825/1995-1191-2010-1-51-55","url":null,"abstract":"The dependence between minute calcium and sodium excretion from 1 L glomerular fi ltrate (CaE/GFR; NaE/GFR) with NaE/GFR from 0,1 to 9,71 mmol/l GFR was studied in 103 health volunteers. There was received asymptotique curve with r 2 = 0,54; Y = 0,06 [1 – exp (–x/2,34)]. The nomogramm with con fi dence intervals of 95% was built. On the basis of renal physiology it was offered differentiate gradual (to electrochemical gradiate created by sodium reabsorbtion) and active calcium reabsorbtion. It was assumed that gradual calcium reabsorbtion is equel to sodium reabsorbtion and may be estimate by NaE/GFR, CNa/GFR. We considered that active calcium reabsorbtion is normal if the correlation between CaE/GFR and NaE/GFR is inside being decreased if the correlation is higher and increased if the correlation is lower probable intervals. We proposed T-score CaE/GFR as the quantative parameter of active calcium reabsorbtion. It varied in health volunteers from –1,74 to +2,15. The method was applied in 236 recipients of allotransplanted kidney.","PeriodicalId":43091,"journal":{"name":"Vestnik Transplantologii i Iskusstvennyh Organov","volume":"12 1","pages":"51-55"},"PeriodicalIF":0.2,"publicationDate":"2014-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67245522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：