Pub Date : 2023-10-26DOI: 10.9734/ca/2023/v12i4374
J. Sado, A. A. Salawu, S. K. Mosaku, T. W. Oloyede, S. A. Ojedokun
Background: Marijuana is the oldest and one of the most widely used illicit drugs, the clinical and pharmacological effects of cannabinoids have been recently studied, with much still unknown about the physiologic and pathologic effects. This study aimed to evaluate its cardiovascular effect using some cardiac makers among smokers in Nigeria.
Methods: The study was a comparative design conducted among eighty-eight test and control subjects. Venous blood was collected for AST, LDH and CK-MB. Biodata was obtained via questionnaires with anthropometric and blood pressure measures. Data were analyzed using SPSS version 21 and a significant level was taken at p<0.05.
Results: There was a decrease in systolic and diastolic blood pressure of subjects who use marijuana as observed from earlier studies. There was a significant increase in the levels of these enzymes in marijuana users as compared to non-smokers.
Conclusion: The increase in these cardiac bio-markers, though heralds the pathologic effect of the use of marijuana on the heart, will be most convincing to assay more cardiac markers such as troponin T to buttress these findings.
背景:大麻是最古老和最广泛使用的非法药物之一，大麻素的临床和药理作用近年来才被研究，但其生理和病理作用尚不清楚。本研究旨在评估其在尼日利亚吸烟者中的心血管效应，使用一些心脏制造商。方法:采用比较设计法，对88名被试和对照组进行研究。采集静脉血检测AST、LDH、CK-MB。生物数据通过人体测量和血压测量问卷获得。数据采用SPSS version 21进行分析，显著水平为p<0.05。
结果:从早期的研究中观察到，使用大麻的受试者的收缩压和舒张压降低。与不吸烟的人相比，吸食大麻的人体内这些酶的水平显著增加。结论:这些心脏生物标记物的增加，虽然预示着大麻使用对心脏的病理影响，但将最有说服力地检测更多的心脏标记物，如肌钙蛋白T，以支持这些发现。
{"title":"Effect of Marijuana on Some Cardiac Biomarkers among Smokers in Southwest Nigeria","authors":"J. Sado, A. A. Salawu, S. K. Mosaku, T. W. Oloyede, S. A. Ojedokun","doi":"10.9734/ca/2023/v12i4374","DOIUrl":"https://doi.org/10.9734/ca/2023/v12i4374","url":null,"abstract":"Background: Marijuana is the oldest and one of the most widely used illicit drugs, the clinical and pharmacological effects of cannabinoids have been recently studied, with much still unknown about the physiologic and pathologic effects. This study aimed to evaluate its cardiovascular effect using some cardiac makers among smokers in Nigeria.
 Methods: The study was a comparative design conducted among eighty-eight test and control subjects. Venous blood was collected for AST, LDH and CK-MB. Biodata was obtained via questionnaires with anthropometric and blood pressure measures. Data were analyzed using SPSS version 21 and a significant level was taken at p<0.05.
 Results: There was a decrease in systolic and diastolic blood pressure of subjects who use marijuana as observed from earlier studies. There was a significant increase in the levels of these enzymes in marijuana users as compared to non-smokers.
 Conclusion: The increase in these cardiac bio-markers, though heralds the pathologic effect of the use of marijuana on the heart, will be most convincing to assay more cardiac markers such as troponin T to buttress these findings.","PeriodicalId":431606,"journal":{"name":"Cardiology and Angiology: An International Journal","volume":"20 4","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134908226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-16DOI: 10.9734/ca/2023/v12i4373
Fatma Ezzat Azzab, Dina Abdelsalam Mostafa, Hanan Kamel Kassem, Hatem Mohamed El Sokkary
Background: The therapy and prognosis of acute myocardial infarction (MI) have been modified by primary percutaneous coronary intervention (PPCI). Delayed time to reperfusion in STEMI patients is risk predictor fo left ventricular diastolic dysfunction and linked to increase risk of heart failure. AMI-associated adverse remodeling, a higher possibility of heart failure, and reduced survival are all linked to echocardiographic indicators of diastolic dysfunction.
Aims: The aim of this study was to determine the relationship between left ventricular diastolic functioning and time-to-reperfusion by PPCI for individuals with STEMI.
Patients and Methods: The current study included 50 patients admitted with STEMI & underwent primary PCI in Cardiology Department in Tanta University Hospitals.
They were divided into two groups: Group 1 early reperfusion (<6h) and group 2 delayed reperfusion (>6h).
They presented by chest pain within 24 hours and conducted echocardiography within 72-hours of PPCI.
Results: The median time-to-reperfusion, which is the time from the onset of symptoms to reperfusion at the end of PPCI, was 240 minutes (interquartile range: 120-720 minutes). LV ejection fraction and E/septal e' did not vary significantly between both groups. The current research found that those with delayed time to reprfusion were troponin (+), CKMB (+), CRP (+), high LVDd, high E/e` average, high LA volume, high LA volume index and had high grade diastolic dysfunction compared to patients with early time to reperfusion. This study showed that group ІІ was significantly higher than group І regarding to time to reperfusion & diastolic dysfunction.
Conclusion: In PPCI-treated individuals who have STEMI, earlier increased LV diastolic pressure is linked to a longer time-to-reperfusion. We also found that creatine kinase, troponin and CRP were significantly higher in the late reperfusion group compared to early reperfusion group. Time to reperfusion and CRP were significantly associated with LVDD grade. CK, LVDs, LVDd, e´ Lateral, E/e´ Lateral, E/e´ average, LA volume index and Diastolic dysfunction grade were identified as independent predictors for LVDD.
{"title":"Relationship between Left Ventricular Diastolic Function and Time to Reperfusion by Primary Percutaneous Coronary Intervention in ST Segment Elevation Myocardial Infarction Patients","authors":"Fatma Ezzat Azzab, Dina Abdelsalam Mostafa, Hanan Kamel Kassem, Hatem Mohamed El Sokkary","doi":"10.9734/ca/2023/v12i4373","DOIUrl":"https://doi.org/10.9734/ca/2023/v12i4373","url":null,"abstract":"Background: The therapy and prognosis of acute myocardial infarction (MI) have been modified by primary percutaneous coronary intervention (PPCI). Delayed time to reperfusion in STEMI patients is risk predictor fo left ventricular diastolic dysfunction and linked to increase risk of heart failure. AMI-associated adverse remodeling, a higher possibility of heart failure, and reduced survival are all linked to echocardiographic indicators of diastolic dysfunction.
 Aims: The aim of this study was to determine the relationship between left ventricular diastolic functioning and time-to-reperfusion by PPCI for individuals with STEMI.
 Patients and Methods: The current study included 50 patients admitted with STEMI & underwent primary PCI in Cardiology Department in Tanta University Hospitals.
 They were divided into two groups: Group 1 early reperfusion (<6h) and group 2 delayed reperfusion (>6h).
 They presented by chest pain within 24 hours and conducted echocardiography within 72-hours of PPCI.
 Results: The median time-to-reperfusion, which is the time from the onset of symptoms to reperfusion at the end of PPCI, was 240 minutes (interquartile range: 120-720 minutes). LV ejection fraction and E/septal e' did not vary significantly between both groups. The current research found that those with delayed time to reprfusion were troponin (+), CKMB (+), CRP (+), high LVDd, high E/e` average, high LA volume, high LA volume index and had high grade diastolic dysfunction compared to patients with early time to reperfusion. This study showed that group ІІ was significantly higher than group І regarding to time to reperfusion & diastolic dysfunction.
 Conclusion: In PPCI-treated individuals who have STEMI, earlier increased LV diastolic pressure is linked to a longer time-to-reperfusion. We also found that creatine kinase, troponin and CRP were significantly higher in the late reperfusion group compared to early reperfusion group. Time to reperfusion and CRP were significantly associated with LVDD grade. CK, LVDs, LVDd, e´ Lateral, E/e´ Lateral, E/e´ average, LA volume index and Diastolic dysfunction grade were identified as independent predictors for LVDD.","PeriodicalId":431606,"journal":{"name":"Cardiology and Angiology: An International Journal","volume":"43 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136114008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-11DOI: 10.9734/ca/2023/v12i4372
Moukhtar Ben Kabbour, Kamel Ghanem, Mohsine Naâim, Mohammed El Jamili, Saloua El Karimi, Mustapha El Hattaoui
Coronary heart disease is one of the world's leading causes of morbidity and mortality. Much is known about left ventricular myocardial infarction. It was not until much later (1974) that right ventricular myocardial infarction was studied as a distinct entity [1]. Isolated VD MI is rare [2,3,4]. It is often associated with infero-posterior MI (in a third of patients) [2,5], with higher morbidity and in-hospital mortality due to hemodynamic and rhythmic complications [4]. The culprit lesion is often occlusion of the proximal right coronary artery [2,4,6,7]. However, the VD is relatively resistant to infarction and recovers even after prolonged occlusion [8]. In this work, we will study the epidemiological, clinical, electrical, echocardiographic and angiographic aspects of MDI with extension to the VD, as well as its complications and therapeutic modalities.
{"title":"Right Ventricular Myocardial Infarction: A Mono-Centric Retrospective Study","authors":"Moukhtar Ben Kabbour, Kamel Ghanem, Mohsine Naâim, Mohammed El Jamili, Saloua El Karimi, Mustapha El Hattaoui","doi":"10.9734/ca/2023/v12i4372","DOIUrl":"https://doi.org/10.9734/ca/2023/v12i4372","url":null,"abstract":"Coronary heart disease is one of the world's leading causes of morbidity and mortality. Much is known about left ventricular myocardial infarction. It was not until much later (1974) that right ventricular myocardial infarction was studied as a distinct entity [1]. Isolated VD MI is rare [2,3,4]. It is often associated with infero-posterior MI (in a third of patients) [2,5], with higher morbidity and in-hospital mortality due to hemodynamic and rhythmic complications [4]. The culprit lesion is often occlusion of the proximal right coronary artery [2,4,6,7]. However, the VD is relatively resistant to infarction and recovers even after prolonged occlusion [8]. In this work, we will study the epidemiological, clinical, electrical, echocardiographic and angiographic aspects of MDI with extension to the VD, as well as its complications and therapeutic modalities.","PeriodicalId":431606,"journal":{"name":"Cardiology and Angiology: An International Journal","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136210532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-11DOI: 10.9734/ca/2023/v12i4371
None Charfo Bacharou M., None Boutar Sidi M., Mokri Anas, None Haboub M., None Arouss S., None Ghali B., None Habbal R.
Introduction: Cardiac myxoma is a primary benign tumor most often located in the left atrium and it is a rare source of cerebral stroke of young subjects.
Case Presentation: We report the case of a young women with cardiac myxoma revelated by hemiplegia.
The patient suddenly presented vertigo followed by a fall, a heaviness of her left body, and dysarthria.
Brain CT tomography and magnetic resonance imaging revealed cerebral ischemia in the right Sylvian territory. Transthoracic echocardiography revealed a round cardiac mass, mobile, heterogeneous, multilobed, appended to the interatrial septum and the atrial side of the large mitral valve by wide implantation, measuring 38 x 25mm in the parasternal short axis (PSAX) and apical 4 chamber views evocative of left atrium myxoma. After the surgical resection, which was postponed for a month, the removed tumor was sent for histopathological examination. The morphological examination revealed a myxoid tumor proliferation compatible with cardiac myxoma expressing calretinin by these tumor cells in the immunohistochemical study.
Conclusion: Left atrium myxoma is a benign cardiac tumor and a rare cause of ischemic stroke. Transthoracic echocardiography facilitates the diagnosis of this tumor which will then be confirmed by histological analysis.
简介:心脏黏液瘤是一种原发性良性肿瘤，常位于左心房，是年轻人脑中风的罕见来源。
病例介绍:我们报告一例年轻女性心脏黏液瘤并发偏瘫。
患者突然出现眩晕，随后摔倒，左侧身体沉重，构音障碍。脑CT和磁共振成像显示右脑区域脑缺血。经胸超声心动图显示一圆形心脏肿块，可移动，异质性，多叶，通过宽植入附于房间隔和大二尖瓣的心房侧，胸骨旁短轴(PSAX)和根尖4室视野，尺寸为38 x 25mm，令人想起左心房黏液瘤。手术切除后，推迟了一个月，切除的肿瘤被送去做组织病理检查。形态学检查显示，这些肿瘤细胞在免疫组化研究中表达calretinin的黏液样肿瘤增殖与心脏黏液瘤相容。
结论:左心房黏液瘤是一种良性心脏肿瘤，是引起缺血性脑卒中的罕见病因。经胸超声心动图有助于诊断这种肿瘤，然后通过组织学分析加以证实。
{"title":"Left Atrial Myxoma Revealed by a Stroke in a Young Female Patient","authors":"None Charfo Bacharou M., None Boutar Sidi M., Mokri Anas, None Haboub M., None Arouss S., None Ghali B., None Habbal R.","doi":"10.9734/ca/2023/v12i4371","DOIUrl":"https://doi.org/10.9734/ca/2023/v12i4371","url":null,"abstract":"Introduction: Cardiac myxoma is a primary benign tumor most often located in the left atrium and it is a rare source of cerebral stroke of young subjects.
 Case Presentation: We report the case of a young women with cardiac myxoma revelated by hemiplegia.
 The patient suddenly presented vertigo followed by a fall, a heaviness of her left body, and dysarthria.
 Brain CT tomography and magnetic resonance imaging revealed cerebral ischemia in the right Sylvian territory. Transthoracic echocardiography revealed a round cardiac mass, mobile, heterogeneous, multilobed, appended to the interatrial septum and the atrial side of the large mitral valve by wide implantation, measuring 38 x 25mm in the parasternal short axis (PSAX) and apical 4 chamber views evocative of left atrium myxoma. After the surgical resection, which was postponed for a month, the removed tumor was sent for histopathological examination. The morphological examination revealed a myxoid tumor proliferation compatible with cardiac myxoma expressing calretinin by these tumor cells in the immunohistochemical study.
 Conclusion: Left atrium myxoma is a benign cardiac tumor and a rare cause of ischemic stroke. Transthoracic echocardiography facilitates the diagnosis of this tumor which will then be confirmed by histological analysis.","PeriodicalId":431606,"journal":{"name":"Cardiology and Angiology: An International Journal","volume":"49 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136211003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-03DOI: 10.9734/ca/2023/v12i4370
P. M. Mulendele, M. Sidi Boutar, B. E. Ovaga, M. Njie, M. Charfo, S. Arous, M. G. Benouna, A. Drighil, L. Azzouzi, R. Habbal
Carbon monoxide (CO) intoxication is the most frequent etiology of toxicological morbidity and mortality in the world. If the neurological manifestations are in the foreground, then cardiovascular signs of myocardial damage by necrosis are possible, which can result in angina, an acute coronary syndrome followed by myocardial stupor, collapse or even cardiac arrest.
We report a case of CO intoxication inducing an acute coronary syndrome without ST elevation in an elderly diabetic patient with no coronary artery disease history.
Diagnosis: This patient presented a CO intoxication after an accidental exposure; the electrocardiogram showed a depressed ST segment of the inferior and apico-lateral leads; cardiac enzyme troponins gradually increased. Echocardiography showed a preserved systolic function with a disorder of the heart wall motions. Coronary angiography revealed significant lesions of the proximal left anterior descending artery (LAD) and the first marginal evoking a diagnosis of acute coronary syndrome induced by CO intoxication.
Interventions: His management consisted of the administration of hyperbaric oxygen therapy, a platelet aggregation inhibitor (aspirin plus clopidogrel), an anticoagulant (low molecular weight heparin) and myocardial support (Bisoprolol). Coronary angiography and the placement of two active stents were performed after 24hrs onset diagnosis.
Results: The patient had a good clinical outcome under hyperbaric oxygen therapy, complete revascularization of the angiographic lesions which showed improvement in cardiac function and a slight improvement of heart wall motion on echocardiography performed on the 5th day. After 6 days, the patient had recovered well and was discharged from the hospital without chest discomfort, dizziness or headache.
Lecture: This case suggests that the symptoms of carbon monoxide intoxication are complex and diverse. This can manifest as a primary hypoxic symptom or cause an exacerbation of underlying diseases due to hypoxia. Therefore, patients with carbon monoxide intoxication should actively seek a comprehensive cardiac examination to ensure early diagnosis. Whenever necessary, coronary angiography and stent implantation should be performed to improve the patient's chances of survival.
{"title":"Acute Coronary Syndrome Induced by Carbon Monoxide Intoxication: A Case Report","authors":"P. M. Mulendele, M. Sidi Boutar, B. E. Ovaga, M. Njie, M. Charfo, S. Arous, M. G. Benouna, A. Drighil, L. Azzouzi, R. Habbal","doi":"10.9734/ca/2023/v12i4370","DOIUrl":"https://doi.org/10.9734/ca/2023/v12i4370","url":null,"abstract":"Carbon monoxide (CO) intoxication is the most frequent etiology of toxicological morbidity and mortality in the world. If the neurological manifestations are in the foreground, then cardiovascular signs of myocardial damage by necrosis are possible, which can result in angina, an acute coronary syndrome followed by myocardial stupor, collapse or even cardiac arrest.
 We report a case of CO intoxication inducing an acute coronary syndrome without ST elevation in an elderly diabetic patient with no coronary artery disease history.
 Diagnosis: This patient presented a CO intoxication after an accidental exposure; the electrocardiogram showed a depressed ST segment of the inferior and apico-lateral leads; cardiac enzyme troponins gradually increased. Echocardiography showed a preserved systolic function with a disorder of the heart wall motions. Coronary angiography revealed significant lesions of the proximal left anterior descending artery (LAD) and the first marginal evoking a diagnosis of acute coronary syndrome induced by CO intoxication.
 Interventions: His management consisted of the administration of hyperbaric oxygen therapy, a platelet aggregation inhibitor (aspirin plus clopidogrel), an anticoagulant (low molecular weight heparin) and myocardial support (Bisoprolol). Coronary angiography and the placement of two active stents were performed after 24hrs onset diagnosis.
 Results: The patient had a good clinical outcome under hyperbaric oxygen therapy, complete revascularization of the angiographic lesions which showed improvement in cardiac function and a slight improvement of heart wall motion on echocardiography performed on the 5th day. After 6 days, the patient had recovered well and was discharged from the hospital without chest discomfort, dizziness or headache.
 Lecture: This case suggests that the symptoms of carbon monoxide intoxication are complex and diverse. This can manifest as a primary hypoxic symptom or cause an exacerbation of underlying diseases due to hypoxia. Therefore, patients with carbon monoxide intoxication should actively seek a comprehensive cardiac examination to ensure early diagnosis. Whenever necessary, coronary angiography and stent implantation should be performed to improve the patient's chances of survival.","PeriodicalId":431606,"journal":{"name":"Cardiology and Angiology: An International Journal","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135696337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Acute Coronary Syndrome (ACS) is a major cardiovascular problem and has been one of the leading death in the world. ST-Elevation Myocardial Infarction (STEMI) is an indicator of total coronary artery occlusion which requires revascularization to restore the blood flow and myocardial reperfusion using fibrinolytic agents or primary Percutaneous Coronary Intervention (PCI). Early treatment showed better outcomes and reduced in-hospital mortality in ACS patients.
Aims: To determine the prevalence of Acute Coronary Syndrome (ACS) patients and the risk factors of in-hospital mortality of ST-Elevation Myocardial Infarction (STEMI) patients at Bekasi Regency General Hospital in 2021.
Place and Duration of Study: Cardiology Department and Emergency Room Unit in Bekasi Regency General Hospital, December 2021 to March 2022
Methods: This study is a descriptive cross-sectional study using secondary data (medical records) which included all the patients over 35 years old that admitted through the ER from January to December 2021 with complaints including chest pain or shortness of breath which were later hospitalized. The final sample used in this study is 117 subjects.
Results: There were 117 cases of ACS in 2021. They were 14% STEMI, 15% Non-ST Elevation Myocardial Infarction (NSTEMI), and 71% Unstable Angina Pectoris (UAP). Most patients were male (54%), and aged <65 years old (85%). The in-hospital mortality was 19% STEMI, 17% NSTEMI, and 12% UAP. Among 16 STEMI patients, 81% were male and 94% were aged <65 years old. There were 69% who came to the emergency room <12 hours and only 50% underwent fibrinolytic.
Conclusion: The risk factors of in-hospital mortality of STEMI patients were 40% late onset, 23% anterior STEMI, 20% hypertension, 60% diabetes mellitus, 50% chronic kidney disease, 33% tachycardia, and 100% Killip III.
{"title":"Prevalence and Risk Factors of In-Hospital Mortality of ST Elevation Myocardial Infarction (STEMI) Patients in Bekasi Regency General Hospital in 2021","authors":"Khanza Rizqullah Syauqi, Mailani Karina Akhmad, Omar Mokhtar Siregar","doi":"10.9734/ca/2023/v12i4369","DOIUrl":"https://doi.org/10.9734/ca/2023/v12i4369","url":null,"abstract":"Background: Acute Coronary Syndrome (ACS) is a major cardiovascular problem and has been one of the leading death in the world. ST-Elevation Myocardial Infarction (STEMI) is an indicator of total coronary artery occlusion which requires revascularization to restore the blood flow and myocardial reperfusion using fibrinolytic agents or primary Percutaneous Coronary Intervention (PCI). Early treatment showed better outcomes and reduced in-hospital mortality in ACS patients.
 Aims: To determine the prevalence of Acute Coronary Syndrome (ACS) patients and the risk factors of in-hospital mortality of ST-Elevation Myocardial Infarction (STEMI) patients at Bekasi Regency General Hospital in 2021.
 Place and Duration of Study: Cardiology Department and Emergency Room Unit in Bekasi Regency General Hospital, December 2021 to March 2022
 Methods: This study is a descriptive cross-sectional study using secondary data (medical records) which included all the patients over 35 years old that admitted through the ER from January to December 2021 with complaints including chest pain or shortness of breath which were later hospitalized. The final sample used in this study is 117 subjects.
 Results: There were 117 cases of ACS in 2021. They were 14% STEMI, 15% Non-ST Elevation Myocardial Infarction (NSTEMI), and 71% Unstable Angina Pectoris (UAP). Most patients were male (54%), and aged <65 years old (85%). The in-hospital mortality was 19% STEMI, 17% NSTEMI, and 12% UAP. Among 16 STEMI patients, 81% were male and 94% were aged <65 years old. There were 69% who came to the emergency room <12 hours and only 50% underwent fibrinolytic.
 Conclusion: The risk factors of in-hospital mortality of STEMI patients were 40% late onset, 23% anterior STEMI, 20% hypertension, 60% diabetes mellitus, 50% chronic kidney disease, 33% tachycardia, and 100% Killip III.","PeriodicalId":431606,"journal":{"name":"Cardiology and Angiology: An International Journal","volume":"51 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135895252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
We present a case report of a 47-year-old male with a known history of recent diabetes who presented with symptoms suggestive of Dressler syndrome, along with the incidental finding of a left ventricular aneurysm. Dressler syndrome is a delayed immune-mediated response following myocardial injury, commonly observed post-myocardial infarction (MI) or cardiac surgery. This case highlights the importance of recognizing the atypical presentation of Dressler syndrome and its association with complications such as ventricular aneurysm, particularly in patients with pre-existing comorbidities.
{"title":"Case Report of Dressler Syndrome and Left Ventricular Aneurysm in a 47-Year-Old Male with Diabetes","authors":"Mounaouir Karim, Nachid Mohammed, Eljazouli Ali, Benhar Ismail, Meryem Haboub, Salim Arous, Ghali Mohamed Bennouna, Abdenasser Drighil, Habbal Rachida","doi":"10.9734/ca/2023/v12i4368","DOIUrl":"https://doi.org/10.9734/ca/2023/v12i4368","url":null,"abstract":"We present a case report of a 47-year-old male with a known history of recent diabetes who presented with symptoms suggestive of Dressler syndrome, along with the incidental finding of a left ventricular aneurysm. Dressler syndrome is a delayed immune-mediated response following myocardial injury, commonly observed post-myocardial infarction (MI) or cardiac surgery. This case highlights the importance of recognizing the atypical presentation of Dressler syndrome and its association with complications such as ventricular aneurysm, particularly in patients with pre-existing comorbidities.","PeriodicalId":431606,"journal":{"name":"Cardiology and Angiology: An International Journal","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135344281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-26DOI: 10.9734/ca/2023/v12i4367
Abdelrahman Adel Taha Shone, Mohammed Ahmed Elbarbary, Suzan Bayoumy Elhefnawy, Mona Adel Elsaidy
Background: Cardiovascular diseases are significant contributors to global increased mortality rates. coronary artery disease (CAD) is the most common cause of heart disease globally.
Aims: Detection of the characteristics [clinical, electrocardiographic, echocardiographic and coronary angiographic] of ischemic heart disease patients in Med Delta region in Egypt and also their management plan.
Methodology: The registry included 1000 patients of ischemic heart disease (IDH) at Med Delta Region. All patients underwent full medical history, full cardiac examination, detection of ECG changes, cardiac enzymes, other labs, Echocardiography and coronary angiography
Results: Out of 1000 patients studied 72.1% had chronic coronary syndromes and 27.9% had acute coronary syndrome. Seven hundreds and sixty-seven (76.7%) were known to have hypertension and 725 (72.5%) patients were smokers. left anterior descending artery (LAD) was diseased in 54.9 % of the patients. Single vessel disease was affected in 61.7%, 21.5% had double vessel disease and about 16.8 % had multi vessel disease.
Conclusion: Chronic coronary syndrome was the most common presentation in the studied patients with hypertension being the most prevalent risk factor and LAD was the mostly affected vessel.
{"title":"Registry of Ischemic Heart Disease Patients in the Region of Mid Delta, Egypt Data Base and Quality Initiative Project","authors":"Abdelrahman Adel Taha Shone, Mohammed Ahmed Elbarbary, Suzan Bayoumy Elhefnawy, Mona Adel Elsaidy","doi":"10.9734/ca/2023/v12i4367","DOIUrl":"https://doi.org/10.9734/ca/2023/v12i4367","url":null,"abstract":"Background: Cardiovascular diseases are significant contributors to global increased mortality rates. coronary artery disease (CAD) is the most common cause of heart disease globally.
 Aims: Detection of the characteristics [clinical, electrocardiographic, echocardiographic and coronary angiographic] of ischemic heart disease patients in Med Delta region in Egypt and also their management plan.
 Methodology: The registry included 1000 patients of ischemic heart disease (IDH) at Med Delta Region. All patients underwent full medical history, full cardiac examination, detection of ECG changes, cardiac enzymes, other labs, Echocardiography and coronary angiography
 Results: Out of 1000 patients studied 72.1% had chronic coronary syndromes and 27.9% had acute coronary syndrome. Seven hundreds and sixty-seven (76.7%) were known to have hypertension and 725 (72.5%) patients were smokers. left anterior descending artery (LAD) was diseased in 54.9 % of the patients. Single vessel disease was affected in 61.7%, 21.5% had double vessel disease and about 16.8 % had multi vessel disease.
 Conclusion: Chronic coronary syndrome was the most common presentation in the studied patients with hypertension being the most prevalent risk factor and LAD was the mostly affected vessel.","PeriodicalId":431606,"journal":{"name":"Cardiology and Angiology: An International Journal","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134960313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Myocarditis is a rare but potentially life-threatening condition that involves inflammation of the heart muscle. It can present with a wide range of clinical manifestations, including acute heart failure, arrhythmias, and ventricular dysfunction. In rare cases, myocarditis can lead to the formation of interventricular communication, which is an abnormal communication between the left and right ventricles. We present a case report of a 31-year-old male who presented to the emergency department with acute heart failure and was subsequently diagnosed with myocarditis causing interventricular communication.
{"title":"A Rare Case of Myocarditis Causing Interventricular Communication and Acute Heart Failure","authors":"Mounaouir Karim, Nachid Mohammed, Mehdi Rochd, Benhar Ismail, Meryem Haboub, Salim Arous, Ghali Mohamed Bennouna, Abdenasser Drighil, Habbal Rachida","doi":"10.9734/ca/2023/v12i4366","DOIUrl":"https://doi.org/10.9734/ca/2023/v12i4366","url":null,"abstract":"Myocarditis is a rare but potentially life-threatening condition that involves inflammation of the heart muscle. It can present with a wide range of clinical manifestations, including acute heart failure, arrhythmias, and ventricular dysfunction. In rare cases, myocarditis can lead to the formation of interventricular communication, which is an abnormal communication between the left and right ventricles. We present a case report of a 31-year-old male who presented to the emergency department with acute heart failure and was subsequently diagnosed with myocarditis causing interventricular communication.","PeriodicalId":431606,"journal":{"name":"Cardiology and Angiology: An International Journal","volume":"58 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134960160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-25DOI: 10.9734/ca/2023/v12i4365
P. M. Mulendele, S. Halim, M. Njie, M. S. Boutar, A. Assklou, M. Haboub, G. M. Benouna, A. Drighil, R. Habbal
Vitamin k antagonist anticoagulants (VKAs) and non-vitamin K oral anticoagulants (NOACs) are widely used in the treatment of non-valvular atrial fibrillation and other indications, but both classes of medications carry a risk of potentially serious bleeding. Spontaneous hematoma of the rectus abdominis muscle is a rare complication of NOAC treatment. Several risk factors, such as trauma, surgery, anticoagulation, coughing, intense rectus muscle contractions, pregnancy, etc., have been reported to cause rectus sheath hematoma. We report a case of spontaneous hematoma of the rectus abdominis muscle associated with moderate hemoperitoneum in a patient treated with NOAC for non-valvular atrial fibrillation (AF). Abdominal ultrasound and computed tomography scan (CT scan) confirmed the diagnosis after clinical assessment. The treatment was generally conservative but in the case of a hemodynamically unstable patient; hemostatic procedures should be considered.
{"title":"Spontaneous Hematoma of the Rectus Abdominis Muscle During Treatment with Non-vitamin K Oral Anticoagulant: A Rare Clinical Occurrence and Review of the Literature","authors":"P. M. Mulendele, S. Halim, M. Njie, M. S. Boutar, A. Assklou, M. Haboub, G. M. Benouna, A. Drighil, R. Habbal","doi":"10.9734/ca/2023/v12i4365","DOIUrl":"https://doi.org/10.9734/ca/2023/v12i4365","url":null,"abstract":"Vitamin k antagonist anticoagulants (VKAs) and non-vitamin K oral anticoagulants (NOACs) are widely used in the treatment of non-valvular atrial fibrillation and other indications, but both classes of medications carry a risk of potentially serious bleeding. Spontaneous hematoma of the rectus abdominis muscle is a rare complication of NOAC treatment. Several risk factors, such as trauma, surgery, anticoagulation, coughing, intense rectus muscle contractions, pregnancy, etc., have been reported to cause rectus sheath hematoma. We report a case of spontaneous hematoma of the rectus abdominis muscle associated with moderate hemoperitoneum in a patient treated with NOAC for non-valvular atrial fibrillation (AF). Abdominal ultrasound and computed tomography scan (CT scan) confirmed the diagnosis after clinical assessment. The treatment was generally conservative but in the case of a hemodynamically unstable patient; hemostatic procedures should be considered.","PeriodicalId":431606,"journal":{"name":"Cardiology and Angiology: An International Journal","volume":"55 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135815776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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