首页 > 最新文献

GMS Interdisciplinary Plastic and Reconstructive Surgery DGPW最新文献

英文 中文
Organoaxial gastric volvulus: a rare cause of an acute abdomen. 器官轴性胃扭转:引起急腹症的罕见原因。
IF 0.4 Q3 SURGERY Pub Date : 2019-03-25 eCollection Date: 2019-01-01 DOI: 10.3205/iprs000130
Katrin Bauer, Christof Keller

We report the case of a 65-year-old male patient with massive epigastric pain of sudden onset and vomiting due to an organoaxial volvulus of the stomach. We comment on the surgical management in our case and discuss etiology and therapeutic options of this rare entity.

我们报告一个65岁的男性病人,由于胃的器官轴向扭转,突然发作和呕吐的大量胃脘痛。我们评论手术管理在我们的情况下,并讨论病因和治疗选择这种罕见的实体。
{"title":"Organoaxial gastric volvulus: a rare cause of an acute abdomen.","authors":"Katrin Bauer,&nbsp;Christof Keller","doi":"10.3205/iprs000130","DOIUrl":"https://doi.org/10.3205/iprs000130","url":null,"abstract":"<p><p>We report the case of a 65-year-old male patient with massive epigastric pain of sudden onset and vomiting due to an organoaxial volvulus of the stomach. We comment on the surgical management in our case and discuss etiology and therapeutic options of this rare entity.</p>","PeriodicalId":43347,"journal":{"name":"GMS Interdisciplinary Plastic and Reconstructive Surgery DGPW","volume":"8 ","pages":"Doc04"},"PeriodicalIF":0.4,"publicationDate":"2019-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441817/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37150776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Painful Vater-Pacini neuroma of the digit in neurofibromatosis type 1. 1型神经纤维瘤病患者手指的疼痛性Vater-Pacini神经瘤。
IF 0.4 Q3 SURGERY Pub Date : 2019-02-08 eCollection Date: 2019-01-01 DOI: 10.3205/iprs000129
Reinhard E Friedrich, Christian Hagel

Vater-Pacini neuromas are rare causes of severe pain in the phalanges. The cause of this change in the tactile corpuscles is unknown. A traumatic cause has been plausibly demonstrated, at least in some cases. Here, the rare occurrence of a Vater-Pacini neuroma in a patient with neurofibromatosis type 1 is reported. The discussion addresses the difficulties of terminology and current diagnostic procedures for differentiating small nodular masses of the palm and digits. The surgical treatment leads to rapid relief of the symptoms.

瓦特-帕西尼神经瘤是罕见的导致指骨剧烈疼痛的原因。触觉小体发生这种变化的原因尚不清楚。至少在某些案例中,创伤性原因已被合理地证明。本文报道一例罕见的1型神经纤维瘤患者发生Vater-Pacini神经瘤。讨论解决的困难的术语和目前的诊断程序,以区分手掌和手指的小结节肿块。手术治疗可迅速缓解症状。
{"title":"Painful Vater-Pacini neuroma of the digit in neurofibromatosis type 1.","authors":"Reinhard E Friedrich,&nbsp;Christian Hagel","doi":"10.3205/iprs000129","DOIUrl":"https://doi.org/10.3205/iprs000129","url":null,"abstract":"<p><p>Vater-Pacini neuromas are rare causes of severe pain in the phalanges. The cause of this change in the tactile corpuscles is unknown. A traumatic cause has been plausibly demonstrated, at least in some cases. Here, the rare occurrence of a Vater-Pacini neuroma in a patient with neurofibromatosis type 1 is reported. The discussion addresses the difficulties of terminology and current diagnostic procedures for differentiating small nodular masses of the palm and digits. The surgical treatment leads to rapid relief of the symptoms.</p>","PeriodicalId":43347,"journal":{"name":"GMS Interdisciplinary Plastic and Reconstructive Surgery DGPW","volume":"8 ","pages":"Doc03"},"PeriodicalIF":0.4,"publicationDate":"2019-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441816/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37150775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Management of Fournier's gangrene with skin grafting by bagging technique of testes: case report. 睾丸袋化植皮治疗富尼耶坏疽1例。
IF 0.4 Q3 SURGERY Pub Date : 2019-02-04 eCollection Date: 2019-01-01 DOI: 10.3205/iprs000128
Yasir Ali AlShehri, Hiba AlBurshaid, Layan AlBassam, Khalid AlMutairi

Aim: To share our experience with the management of Fournier gangrene (FG) using the bagging technique of the testes, and to highlight the importance of implementing a multidisciplinary approach in managing FG. Case presentation: A 58-year-old male with type 2 diabetes mellitus (DM) was brought to the emergency department (ED) with necrotizing fasciitis involving the genitalia; he was managed in the ED with Intravenous (IV) fluid resuscitation and IV antibiotics. The surgical team was consulted and multiple debridement procedures were done. Healthy granulation tissue was formed within one month of the serial debridement. A split-thickness skin graft using bagging technique of the testes and vacuum-assisted closure (VAC) were applied. The patient was reassessed one year following presentation, and a result with a near normal appearance was achieved with complete preservation of functional outcome. Conclusion: FG is a type of necrotizing fasciitis that could be managed either conservatively with IV antibiotics and/or hyperbaric oxygen, or surgically by debridement and applying VAC. In our case, the testes were debrided and bagging technique of the testes was used. It's believed that with this technique, the overall cosmetic and functional results are superior.

目的:分享我们使用睾丸袋装技术治疗富尼耶坏疽(FG)的经验,并强调实施多学科方法治疗FG的重要性。病例介绍:一位58岁男性2型糖尿病(DM)被带到急诊科(ED)坏死性筋膜炎累及生殖器;他在急诊科接受静脉输液复苏和静脉抗生素治疗。我们咨询了外科团队,并进行了多次清创手术。连续清创后一个月内形成健康肉芽组织。采用睾丸囊化技术和真空辅助闭合(VAC)进行分厚皮移植。患者在就诊一年后重新评估,结果显示外观接近正常,功能预后完全保留。结论:FG是一种坏死性筋膜炎,可以通过静脉注射抗生素和/或高压氧进行保守治疗,也可以通过手术清创和应用VAC进行治疗。在我们的病例中,我们对睾丸进行了清理,并使用了睾丸装袋技术。人们相信,采用这种技术,整体的美容和功能效果都是优越的。
{"title":"Management of Fournier's gangrene with skin grafting by bagging technique of testes: case report.","authors":"Yasir Ali AlShehri,&nbsp;Hiba AlBurshaid,&nbsp;Layan AlBassam,&nbsp;Khalid AlMutairi","doi":"10.3205/iprs000128","DOIUrl":"https://doi.org/10.3205/iprs000128","url":null,"abstract":"<p><p><b>Aim:</b> To share our experience with the management of Fournier gangrene (FG) using the bagging technique of the testes, and to highlight the importance of implementing a multidisciplinary approach in managing FG. <b>Case</b> <b>presentation:</b> A 58-year-old male with type 2 diabetes mellitus (DM) was brought to the emergency department (ED) with necrotizing fasciitis involving the genitalia; he was managed in the ED with Intravenous (IV) fluid resuscitation and IV antibiotics. The surgical team was consulted and multiple debridement procedures were done. Healthy granulation tissue was formed within one month of the serial debridement. A split-thickness skin graft using bagging technique of the testes and vacuum-assisted closure (VAC) were applied. The patient was reassessed one year following presentation, and a result with a near normal appearance was achieved with complete preservation of functional outcome. <b>Conclusion:</b> FG is a type of necrotizing fasciitis that could be managed either conservatively with IV antibiotics and/or hyperbaric oxygen, or surgically by debridement and applying VAC. In our case, the testes were debrided and bagging technique of the testes was used. It's believed that with this technique, the overall cosmetic and functional results are superior.</p>","PeriodicalId":43347,"journal":{"name":"GMS Interdisciplinary Plastic and Reconstructive Surgery DGPW","volume":"8 ","pages":"Doc02"},"PeriodicalIF":0.4,"publicationDate":"2019-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379833/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37018381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Nasofrontal surgical reconstruction by external table flap of frontal bone following removal of a dermoid cyst revealed by a fistula: A case report and review of the literature. 以鼻额骨外桌瓣重建以瘘管显示的皮样囊肿:1例报告及文献复习。
IF 0.4 Q3 SURGERY Pub Date : 2019-01-30 eCollection Date: 2019-01-01 DOI: 10.3205/iprs000127
Kamal Chtira, Yassine Elallouchi, Farid Zahrou, Mouhssine Assamadi, Abdelaziz Ait El Qadi, Houssaine Ghannane, Mehdi Laghmari

Nasofrontal fistulas correspond to the persistence of an abnormal communication of embryological origin between the deep layer of the skin and the central nervous system (CNS). They can rarely be associated with a dermoid cyst and be revealed by a locoregional infection, and especially neuromeningeal infections can be serious. The treatment is mainly surgical by performing a total excision of the cyst and the repair of defects. The authors report the case of an 18-month-old infant operated for a dermoid cyst revealed by a nasofrontal fistula. They insist on the characteristics of this pathology in order to establish a diagnosis and an early treatment to avoid the complications that can be heavy in certain cases. They describe the steps of nasofrontal reconstruction by a small flap taken from the outer table of the frontal bone with better esthetic results.

鼻额叶瘘管与胚胎起源的皮肤深层和中枢神经系统(CNS)之间的异常通信的持续一致。它们很少与皮样囊肿相关,并由局部感染显示,特别是神经脑膜感染可能很严重。治疗主要是外科手术,完全切除囊肿并修复缺陷。作者报告的情况下,18个月大的婴儿手术皮样囊肿显示鼻额瘘。他们坚持这种病理的特点,以便建立诊断和早期治疗,以避免在某些情况下可能严重的并发症。他们描述了从额骨外表取一个小皮瓣重建鼻额叶的步骤,具有更好的美学效果。
{"title":"Nasofrontal surgical reconstruction by external table flap of frontal bone following removal of a dermoid cyst revealed by a fistula: A case report and review of the literature.","authors":"Kamal Chtira,&nbsp;Yassine Elallouchi,&nbsp;Farid Zahrou,&nbsp;Mouhssine Assamadi,&nbsp;Abdelaziz Ait El Qadi,&nbsp;Houssaine Ghannane,&nbsp;Mehdi Laghmari","doi":"10.3205/iprs000127","DOIUrl":"https://doi.org/10.3205/iprs000127","url":null,"abstract":"<p><p>Nasofrontal fistulas correspond to the persistence of an abnormal communication of embryological origin between the deep layer of the skin and the central nervous system (CNS). They can rarely be associated with a dermoid cyst and be revealed by a locoregional infection, and especially neuromeningeal infections can be serious. The treatment is mainly surgical by performing a total excision of the cyst and the repair of defects. The authors report the case of an 18-month-old infant operated for a dermoid cyst revealed by a nasofrontal fistula. They insist on the characteristics of this pathology in order to establish a diagnosis and an early treatment to avoid the complications that can be heavy in certain cases. They describe the steps of nasofrontal reconstruction by a small flap taken from the outer table of the frontal bone with better esthetic results.</p>","PeriodicalId":43347,"journal":{"name":"GMS Interdisciplinary Plastic and Reconstructive Surgery DGPW","volume":"8 ","pages":"Doc01"},"PeriodicalIF":0.4,"publicationDate":"2019-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379832/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37018380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Prone positioning in the elderly extends perioperative process times: a retrospective analysis. 老年人俯卧位延长围手术期时间:回顾性分析。
IF 0.4 Q3 SURGERY Pub Date : 2018-12-06 eCollection Date: 2018-01-01 DOI: 10.3205/iprs000126
Joerg Schnoor, Christoph E Heyde, Mary Niese-Anke, Steffen Friese, Thilo Busch, Jan-S Jarvers

Objective: Cervical bone fractures describe a predominant trauma in the elderly. With demographic change, prone patient positions might create further stress on personnel resources. Therefore, the aim of this study was to conduct an age-related analysis of pre- and intraoperative process times in patients with cervical fractures. Methods: We reviewed all schedules with cervical spine surgery performed at a tertiary hospital. Two different operative patient positions were specified: prone and supine. We retrospectively analysed three study groups: comparison group (group 1: ≤59 years of age), old patients (group 2: 60-79 years), and very old patients (group 3: ≥80 years). We recorded date and kind of surgery, biometric data, and process times by screening recordings of internal software programs (COPRA® and SAP 710®). Group comparisons were conducted using the Kruskal-Wallis test with Dunn's post hoc test and Bonferroni correction, Pearson's chi-square test, and the Mann-Whitney U test, as required. Results: 330 patients (202 male; 128 female) were analysed. The number of patients in the resulting age-dependent groups 1-3 were n=102, n=123, and n=105, respectively. Patients of increasing age and in supine position showed a continuous increase in the time needed for anaesthesia induction (mean between 4 and 8 minutes (p<0.05). When compared to patients in supine position, this time further increased on average by 6 minutes (p<0.05) in old but prone patients. In old and very old patients, getting a patient into a prone position was associated with a time demand between 10 and 12 minutes (p<0.01), respectively. While time for surgery age-dependently decreased in patients that were supine positioned (p<0.001), surgery time was prolonged between 34 and 104 minutes (p<0.05) in patients that were prone. Conclusion: With prone position both anaesthesia-controlled and surgical-controlled times extended in patients of increasing age. With regard to demographic change, this aspect should be considered for future revenue calculations in flat-rate remuneration systems.

目的:颈椎骨折是老年人的主要创伤。随着人口结构的变化,病人的俯卧姿势可能会对人力资源造成进一步的压力。因此,本研究的目的是对颈椎骨折患者的术前和术中处理时间进行年龄相关的分析。方法:我们回顾了在一家三级医院进行颈椎手术的所有时间表。两种不同的手术位:俯卧位和仰卧位。我们回顾性分析了三个研究组:对照组(组1:≤59岁)、老年患者(组2:60-79岁)和非常老年患者(组3:≥80岁)。我们通过筛选内部软件程序(COPRA®和SAP 710®)的记录记录手术日期和类型、生物识别数据和处理时间。根据需要,采用Kruskal-Wallis检验、Dunn事后检验和Bonferroni校正、Pearson卡方检验和Mann-Whitney U检验进行组间比较。结果:330例患者(男性202例;128名女性)进行了分析。所得年龄依赖性组1-3的患者人数分别为n=102、n=123和n=105。随着年龄的增长,仰卧位患者麻醉诱导时间持续增加(平均在4 ~ 8分钟之间)。结论:随着年龄的增长,俯卧位麻醉控制时间和手术控制时间均延长。关于人口变化,在统一费率薪酬制度的未来收入计算中应考虑到这一方面。
{"title":"Prone positioning in the elderly extends perioperative process times: a retrospective analysis.","authors":"Joerg Schnoor,&nbsp;Christoph E Heyde,&nbsp;Mary Niese-Anke,&nbsp;Steffen Friese,&nbsp;Thilo Busch,&nbsp;Jan-S Jarvers","doi":"10.3205/iprs000126","DOIUrl":"https://doi.org/10.3205/iprs000126","url":null,"abstract":"<p><p><b>Objective:</b> Cervical bone fractures describe a predominant trauma in the elderly. With demographic change, prone patient positions might create further stress on personnel resources. Therefore, the aim of this study was to conduct an age-related analysis of pre- and intraoperative process times in patients with cervical fractures. <b>Methods:</b> We reviewed all schedules with cervical spine surgery performed at a tertiary hospital. Two different operative patient positions were specified: prone and supine. We retrospectively analysed three study groups: comparison group (group 1: ≤59 years of age), old patients (group 2: 60-79 years), and very old patients (group 3: ≥80 years). We recorded date and kind of surgery, biometric data, and process times by screening recordings of internal software programs (COPRA<sup>®</sup> and SAP 710<sup>®</sup>). Group comparisons were conducted using the Kruskal-Wallis test with Dunn's post hoc test and Bonferroni correction, Pearson's chi-square test, and the Mann-Whitney U test, as required. <b>Results:</b> 330 patients (202 male; 128 female) were analysed. The number of patients in the resulting age-dependent groups 1-3 were n=102, n=123, and n=105, respectively. Patients of increasing age and in supine position showed a continuous increase in the time needed for anaesthesia induction (mean between 4 and 8 minutes (p<0.05). When compared to patients in supine position, this time further increased on average by 6 minutes (p<0.05) in old but prone patients. In old and very old patients, getting a patient into a prone position was associated with a time demand between 10 and 12 minutes (p<0.01), respectively. While time for surgery age-dependently decreased in patients that were supine positioned (p<0.001), surgery time was prolonged between 34 and 104 minutes (p<0.05) in patients that were prone. <b>Conclusion:</b> With prone position both anaesthesia-controlled and surgical-controlled times extended in patients of increasing age. With regard to demographic change, this aspect should be considered for future revenue calculations in flat-rate remuneration systems.</p>","PeriodicalId":43347,"journal":{"name":"GMS Interdisciplinary Plastic and Reconstructive Surgery DGPW","volume":"7 ","pages":"Doc06"},"PeriodicalIF":0.4,"publicationDate":"2018-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287098/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36847936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Conservative treatment of fingertip injuries in children - first experiences with a novel silicone finger cap that enables woundfluid analysis. 儿童指尖损伤的保守治疗-首次使用新颖的硅胶指帽进行伤口液分析。
IF 0.4 Q3 SURGERY Pub Date : 2018-10-19 eCollection Date: 2018-01-01 DOI: 10.3205/iprs000125
Jurek Schultz, Percy Schröttner, Susann Leupold, Adrian Dragu, Silvana Sußmann, Michael Haase, Guido Fitze

Introduction: Human fingertips are able to regenerate soft tissue and skin after amputation injuries with excellent cosmetic and functional results when treated with semiocclusive dressings. Despite bacterial colonizations, proceeding infections are not reported with this management. The underlying mechanisms for this form of regenerative healing as well as for the resilience to infections are not known. Due to the lack of mechanical protection, the leakage of maloderous woundfluid and the sometimes challenging application, conventional film dressings have their problems, especially in treating young children. We therefore treated selected patients with a novel silicone finger cap with an integrated wound fluid reservoir that enables atraumatic routine wound fluid aspiration. Methods: We report on 34 patients in between 1 and 13 years with traumatic fingertip amputations primarily treated with occlusive dressings. 12 patients were treated with a novel silicone finger cap. We summarized clinical data for each patient. This included photographs and microbiological results from wound fluid analyses, whenever available. Results: The results of both, conventional film dressing and silicone finger cap treatment, were excellent with no hypersensitivity and no restrictions in sensibility and motility. Even larger pulp defects were rearranged in a round shape and good soft tissue coverage of the distal phalanx was achieved. Nail deformities were not observed. We detected a wide spectrum of both aerobic and anaerobic bacteria in the wound fluids but infections were not observed. Epithelialization times did not differ significantly and no severe complications were seen in all primarily conservatively treated patients. Conclusion: This study provides preliminary data demonstrating that the treatment with the silicone finger cap leads to excellent clinical results in wound healing. Interestingly, the wounds were colonized with a wide range of bacteria including species that may cause wound infections. However, we saw no proceeding inflammation and the regeneration was undisturbed. In the future, the efficacy of this new management should be evaluated in randomized, controlled clinical trials to confirm the results under standard conditions and get more insight into the role of the wound microbiome as well as other factors that may promote regeneration. The aspirable Reservoir of the finger cap will enable easy atraumatic sampling of wound fluids both for diagnostic and for research purposes as well as possibly allowing direct administration of pro-regenerative drugs in the future.

简介:人类的指尖能够再生软组织和皮肤截肢损伤后,半封闭敷料治疗具有良好的美容和功能效果。尽管细菌定植,继续感染没有报道与这种管理。这种形式的再生愈合的潜在机制以及对感染的恢复能力尚不清楚。传统的膜敷料由于缺乏机械保护、有恶臭的伤口液泄漏以及有时应用困难等原因存在问题,特别是在治疗幼儿时。因此,我们选择了一种新型的硅胶指帽来治疗患者,该指帽带有一个集成的伤口液体储液器,可以实现非创伤性的常规伤口液体抽吸。方法:我们报告了34例1至13年间主要采用封闭敷料治疗的外伤性指尖截肢患者。12例患者接受新型硅胶指帽治疗。我们总结了每位患者的临床资料。这包括照片和伤口液分析的微生物结果,只要有。结果:常规膜敷料和硅胶指帽治疗均无超敏反应,无敏感性和活动性限制。甚至更大的牙髓缺损被重新排列成圆形,远端指骨的软组织覆盖良好。未见指甲畸形。我们在伤口液中检测到广泛的好氧和厌氧细菌,但未观察到感染。上皮化时间无显著差异,在所有主要保守治疗的患者中未见严重并发症。结论:本研究提供了初步数据,证明硅胶指帽治疗创面愈合具有良好的临床效果。有趣的是,伤口被广泛的细菌定植,包括可能导致伤口感染的物种。然而,我们没有看到持续的炎症,再生也没有受到干扰。在未来,这种新的管理方法的疗效需要在随机对照临床试验中进行评估,以在标准条件下确认结果,并进一步了解伤口微生物组的作用以及其他可能促进再生的因素。指帽的可吸入储液器将使伤口液的非创伤性取样变得容易,既可用于诊断,也可用于研究目的,还可能允许将来直接给药促再生药物。
{"title":"Conservative treatment of fingertip injuries in children - first experiences with a novel silicone finger cap that enables woundfluid analysis.","authors":"Jurek Schultz,&nbsp;Percy Schröttner,&nbsp;Susann Leupold,&nbsp;Adrian Dragu,&nbsp;Silvana Sußmann,&nbsp;Michael Haase,&nbsp;Guido Fitze","doi":"10.3205/iprs000125","DOIUrl":"https://doi.org/10.3205/iprs000125","url":null,"abstract":"<p><p><b>Introduction:</b> Human fingertips are able to regenerate soft tissue and skin after amputation injuries with excellent cosmetic and functional results when treated with semiocclusive dressings. Despite bacterial colonizations, proceeding infections are not reported with this management. The underlying mechanisms for this form of regenerative healing as well as for the resilience to infections are not known. Due to the lack of mechanical protection, the leakage of maloderous woundfluid and the sometimes challenging application, conventional film dressings have their problems, especially in treating young children. We therefore treated selected patients with a novel silicone finger cap with an integrated wound fluid reservoir that enables atraumatic routine wound fluid aspiration. <b>Methods:</b> We report on 34 patients in between 1 and 13 years with traumatic fingertip amputations primarily treated with occlusive dressings. 12 patients were treated with a novel silicone finger cap. We summarized clinical data for each patient. This included photographs and microbiological results from wound fluid analyses, whenever available. <b>Results:</b> The results of both, conventional film dressing and silicone finger cap treatment, were excellent with no hypersensitivity and no restrictions in sensibility and motility. Even larger pulp defects were rearranged in a round shape and good soft tissue coverage of the distal phalanx was achieved. Nail deformities were not observed. We detected a wide spectrum of both aerobic and anaerobic bacteria in the wound fluids but infections were not observed. Epithelialization times did not differ significantly and no severe complications were seen in all primarily conservatively treated patients. <b>Conclusion:</b> This study provides preliminary data demonstrating that the treatment with the silicone finger cap leads to excellent clinical results in wound healing. Interestingly, the wounds were colonized with a wide range of bacteria including species that may cause wound infections. However, we saw no proceeding inflammation and the regeneration was undisturbed. In the future, the efficacy of this new management should be evaluated in randomized, controlled clinical trials to confirm the results under standard conditions and get more insight into the role of the wound microbiome as well as other factors that may promote regeneration. The aspirable Reservoir of the finger cap will enable easy atraumatic sampling of wound fluids both for diagnostic and for research purposes as well as possibly allowing direct administration of pro-regenerative drugs in the future.</p>","PeriodicalId":43347,"journal":{"name":"GMS Interdisciplinary Plastic and Reconstructive Surgery DGPW","volume":"7 ","pages":"Doc05"},"PeriodicalIF":0.4,"publicationDate":"2018-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218674/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36678499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Pigmented (melanotic) diffuse neurofibroma of the back in neurofibromatosis type 1. 1型神经纤维瘤病的背部色素性弥漫性神经纤维瘤。
IF 0.4 Q3 SURGERY Pub Date : 2018-08-03 eCollection Date: 2018-01-01 DOI: 10.3205/iprs000124
Reinhard E Friedrich, Christian Hagel

Neurofibromatosis type 1 (NF1) is a tumor predisposition disease. Multiple neurofibromas are among the characteristic tumors of NF1. The report describes the diagnosis and treatment of a large spinal neurofibroma in a NF1 patient. The tumor showed a striking pigmentation and was diagnosed as pigmented (melanotic) neurofibroma. The distinction between this rare tumor variant and other pigmented tumors, especially malignant melanoma, is of primary importance.

1型神经纤维瘤病(NF1)是一种肿瘤易感性疾病。多发性神经纤维瘤是NF1的特征性肿瘤之一。报告描述了一个NF1患者的大脊髓神经纤维瘤的诊断和治疗。肿瘤有明显的色素沉着,诊断为色素(黑素)神经纤维瘤。区分这种罕见的肿瘤变体和其他色素肿瘤,特别是恶性黑色素瘤,是至关重要的。
{"title":"Pigmented (melanotic) diffuse neurofibroma of the back in neurofibromatosis type 1.","authors":"Reinhard E Friedrich,&nbsp;Christian Hagel","doi":"10.3205/iprs000124","DOIUrl":"https://doi.org/10.3205/iprs000124","url":null,"abstract":"<p><p>Neurofibromatosis type 1 (NF1) is a tumor predisposition disease. Multiple neurofibromas are among the characteristic tumors of NF1. The report describes the diagnosis and treatment of a large spinal neurofibroma in a NF1 patient. The tumor showed a striking pigmentation and was diagnosed as pigmented (melanotic) neurofibroma. The distinction between this rare tumor variant and other pigmented tumors, especially malignant melanoma, is of primary importance.</p>","PeriodicalId":43347,"journal":{"name":"GMS Interdisciplinary Plastic and Reconstructive Surgery DGPW","volume":"7 ","pages":"Doc04"},"PeriodicalIF":0.4,"publicationDate":"2018-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073164/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36401104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Management of donor site infections in split-thickness skin graft with water-filtered infrared-A (wIRA). 水滤红外- a (wIRA)处理薄皮移植供体部位感染。
IF 0.4 Q3 SURGERY Pub Date : 2018-06-12 eCollection Date: 2018-01-01 DOI: 10.3205/iprs000123
Anas Aljasir, Thomas Pierson, Gerd Hoffmann, Henrik Menke

Infection of donor sites in split-thickness skin grafts is one of the complications of skin transplantation. Nutrition status and associated diseases play important roles in healing of donor sites. There are different ways used to treat infected donor sites. Water-filtered infrared-A (wIRA), as a special form of heat radiation with a high tissue penetration and a low thermal load to the skin surface, can improve the healing of acute and chronic wounds both by thermal and thermic as well as by non-thermal and non-thermic effects. Water-filtered infrared-A (wIRA) increases tissue temperature, tissue oxygen partial pressure and tissue perfusion. These three factors are decisive for a sufficient supply of tissue with energy and oxygen and consequently also for wound healing and infection defense. This was confirmed in a case with a late severe healing disturbance of the donor sites after skin transplantation.

裂厚皮肤移植供体部位感染是皮肤移植的并发症之一。营养状况及相关疾病在供区愈合中起重要作用。治疗受感染的供体部位有不同的方法。水过滤红外- a (wIRA)作为一种特殊形式的热辐射,对皮肤表面具有高组织穿透性和低热负荷,可以通过热效应和热效应以及非热效应和非热效应促进急慢性伤口的愈合。水过滤红外- a (wIRA)增加组织温度,组织氧分压和组织灌注。这三个因素是决定性的组织与能量和氧气的充足供应,因此也伤口愈合和感染防御。在一例皮肤移植后供体部位出现晚期严重愈合障碍的病例中证实了这一点。
{"title":"Management of donor site infections in split-thickness skin graft with water-filtered infrared-A (wIRA).","authors":"Anas Aljasir,&nbsp;Thomas Pierson,&nbsp;Gerd Hoffmann,&nbsp;Henrik Menke","doi":"10.3205/iprs000123","DOIUrl":"https://doi.org/10.3205/iprs000123","url":null,"abstract":"<p><p>Infection of donor sites in split-thickness skin grafts is one of the complications of skin transplantation. Nutrition status and associated diseases play important roles in healing of donor sites. There are different ways used to treat infected donor sites. Water-filtered infrared-A (wIRA), as a special form of heat radiation with a high tissue penetration and a low thermal load to the skin surface, can improve the healing of acute and chronic wounds both by thermal and thermic as well as by non-thermal and non-thermic effects. Water-filtered infrared-A (wIRA) increases tissue temperature, tissue oxygen partial pressure and tissue perfusion. These three factors are decisive for a sufficient supply of tissue with energy and oxygen and consequently also for wound healing and infection defense. This was confirmed in a case with a late severe healing disturbance of the donor sites after skin transplantation.</p>","PeriodicalId":43347,"journal":{"name":"GMS Interdisciplinary Plastic and Reconstructive Surgery DGPW","volume":"7 ","pages":"Doc03"},"PeriodicalIF":0.4,"publicationDate":"2018-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3205/iprs000123","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36288342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Mid-term results of two-stage revision of total knee arthroplasty using a mobile (dynamic) cement spacer in the treatment of periprosthetic infections. 全膝关节置换术二期翻修中使用移动(动态)水泥间隔器治疗假体周围感染的中期结果。
IF 0.4 Q3 SURGERY Pub Date : 2018-05-18 eCollection Date: 2018-01-01 DOI: 10.3205/iprs0000122
Mohamed Ghanem, Christina Pempe, Dirk Zajonz, Andreas Roth, Christoph-Eckhard Heyde, Christoph Josten

Introduction: Infection of the knee joint after primary total knee arthroplasty is a serious complication. In this work, we would like to evaluate the mid-term results after two-stage revision of total knee replacement in periprosthetic infection using dynamic spacer, in particular with regard to the function of the knee joint after reimplantation. Patients and methods: In this retrospective study, we included patients who were treated in our clinic between 2005 and 2013 due to infection of the knee after total knee arthroplasty. All patients included have had a mobile antibiotic-coated cement spacer implanted after surgical debridement and removal of the components of total knee replacement. Subsequently, reimplantation of total knee replacement was performed when no clinical or paraclinical signs of infection were found. We analyzed all included cases for potential reinfection, examined the range of motion of the knee joint and evaluated the Merle d'Aubigné-Postel score. Statistical evaluation was performed with SPSS 24.0. Results: This study group contains 16 patients (9 women and 7 men) with an average age of 72.0 ± 8.3 years. All patients were followed up for at least 6 months with an average follow-up of 22.5 ± 16.6 months. In all patients a pathogen was isolated intraoperatively during the first-stage surgery (explantation of the knee). Staphylococci were detected in 94% of the cases, streptococci in only one patient. Reimplantation was carried out after 6.2 ± 5.2 months. The average knee flexion in the group of patients without relapse of infection was 103.3° ± 17.1°. Only 3 patients showed extension deficit of max. 20°. The Merle d'Aubigné-Postel Score was 14.4 ± 1.9. Conclusion: Two-stage surgery of total knee replacement with the use of a mobile spacer has its high value in the treatment of periprosthetic infections. The mobile spacers contribute to an advantageous range of motion of the knee joint after reimplantation of a total knee endoprosthesis. However, further studies are required that compare the results after using mobile or static spacer, but with the inclusion of homogeneous patient collective.

初次全膝关节置换术后膝关节感染是一个严重的并发症。在这项工作中,我们想要评估使用动态垫片进行全膝关节置换术两阶段翻修后假体周围感染的中期结果,特别是关于膝关节再植入术后的功能。患者和方法:在这项回顾性研究中,我们纳入了2005年至2013年间因全膝关节置换术后膝关节感染而在我们诊所接受治疗的患者。所有纳入的患者在手术清创和全膝关节置换术部件移除后都植入了可移动的抗生素涂层水泥垫片。随后,在没有发现临床或临床旁感染症状的情况下进行全膝关节置换术。我们分析了所有纳入病例的潜在再感染,检查了膝关节的活动范围,并评估了Merle d' aubigne - postel评分。采用SPSS 24.0进行统计学评价。结果:本组患者16例(女9例,男7例),平均年龄72.0±8.3岁。所有患者均随访至少6个月,平均随访22.5±16.6个月。在所有患者的第一阶段手术(膝关节外植术)中,术中分离出病原体。94%的病例检出葡萄球菌,仅1例检出链球菌。术后6.2±5.2个月再植。无感染复发组患者的平均膝关节屈曲度为103.3°±17.1°。仅有3例患者出现max伸展缺损。20°。Merle d' aubigne - postel评分为14.4±1.9。结论:两期全膝关节置换术联合移动垫片治疗假体周围感染有较高的应用价值。可移动的垫片有助于全膝关节假体植入术后膝关节的有利活动范围。然而,需要进一步的研究来比较使用移动或静态间隔器后的结果,但要纳入均匀的患者群体。
{"title":"Mid-term results of two-stage revision of total knee arthroplasty using a mobile (dynamic) cement spacer in the treatment of periprosthetic infections.","authors":"Mohamed Ghanem,&nbsp;Christina Pempe,&nbsp;Dirk Zajonz,&nbsp;Andreas Roth,&nbsp;Christoph-Eckhard Heyde,&nbsp;Christoph Josten","doi":"10.3205/iprs0000122","DOIUrl":"https://doi.org/10.3205/iprs0000122","url":null,"abstract":"<p><p><b>Introduction:</b> Infection of the knee joint after primary total knee arthroplasty is a serious complication. In this work, we would like to evaluate the mid-term results after two-stage revision of total knee replacement in periprosthetic infection using dynamic spacer, in particular with regard to the function of the knee joint after reimplantation. <b>Patients and methods:</b> In this retrospective study, we included patients who were treated in our clinic between 2005 and 2013 due to infection of the knee after total knee arthroplasty. All patients included have had a mobile antibiotic-coated cement spacer implanted after surgical debridement and removal of the components of total knee replacement. Subsequently, reimplantation of total knee replacement was performed when no clinical or paraclinical signs of infection were found. We analyzed all included cases for potential reinfection, examined the range of motion of the knee joint and evaluated the Merle d'Aubigné-Postel score. Statistical evaluation was performed with SPSS 24.0. <b>Results:</b> This study group contains 16 patients (9 women and 7 men) with an average age of 72.0 ± 8.3 years. All patients were followed up for at least 6 months with an average follow-up of 22.5 ± 16.6 months. In all patients a pathogen was isolated intraoperatively during the first-stage surgery (explantation of the knee). <i>Staphylococci</i> were detected in 94% of the cases, <i>streptococci</i> in only one patient. Reimplantation was carried out after 6.2 ± 5.2 months. The average knee flexion in the group of patients without relapse of infection was 103.3° ± 17.1°. Only 3 patients showed extension deficit of max. 20°. The Merle d'Aubigné-Postel Score was 14.4 ± 1.9. <b>Conclusion:</b> Two-stage surgery of total knee replacement with the use of a mobile spacer has its high value in the treatment of periprosthetic infections. The mobile spacers contribute to an advantageous range of motion of the knee joint after reimplantation of a total knee endoprosthesis. However, further studies are required that compare the results after using mobile or static spacer, but with the inclusion of homogeneous patient collective.</p>","PeriodicalId":43347,"journal":{"name":"GMS Interdisciplinary Plastic and Reconstructive Surgery DGPW","volume":"7 ","pages":"Doc02"},"PeriodicalIF":0.4,"publicationDate":"2018-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994541/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36238606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Coverage of the scrotum after Fournier's gangrene. 富尼耶坏疽后阴囊的覆盖。
IF 0.4 Q3 SURGERY Pub Date : 2018-01-15 eCollection Date: 2018-01-01 DOI: 10.3205/iprs000121
Ahmed Hassan El-Sabbagh

Background: Fournier's gangrene is a necrotizing fasciitis caused by mixed aerobic and anaerobic bacteria and results in loss of skin and subcutaneous tissue in the perineal area. Coverage of testis varies from closure of the defect primarily, burying inside the thigh, using the remnants of the scrotum for tissue expansion and coverage by flaps. In this manuscript, scrotal advancement flaps and pudendal thigh flaps were used for coverage of the testis unilaterally or bilaterally according to the size of the defect following Fournier gangrene. Patients and methods: From June 2015 to March 2017, twelve cases were admitted to our department. The patients' ages ranged from 37-59 years and they all had suffered from Fournier's gangrene in the perineal area. Results: Of the twelve cases, two cases showed penile involvement. A skin graft was used for coverage of the penile shaft with excellent take. Four cases were closed primarily. This was applied to cases where loss of skin was less than 50%. The rest of the cases were reconstructed by pudendal thigh flap. The reconstructed cases were covered by bilateral pudendal thigh flap (4 cases) and unilateral pudendal thigh flap (4 cases). The follow-up extended up to 16 months. Conclusion: Scrotal advancement flap was suitable for small and medium size defects due to the elasticity of the scrotal skin. Pudendal thigh flap was efficient for the reconstruction of large defects of the scrotum.

背景:富尼耶坏疽是一种坏死性筋膜炎,由好氧和厌氧混合细菌引起,导致会阴区皮肤和皮下组织的损失。睾丸的覆盖范围各不相同,主要是闭合缺陷,埋在大腿内,利用阴囊的残余进行组织扩张和皮瓣覆盖。在这篇文章中,根据富尼耶坏疽后的缺陷大小,阴囊前移皮瓣和阴部大腿皮瓣被用于单侧或双侧睾丸的覆盖。患者及方法:2015年6月至2017年3月,我科收治12例患者。患者年龄37 ~ 59岁,均为会阴区富尼耶坏疽。结果:12例患者中2例出现阴茎受累。皮肤移植用于阴茎轴的覆盖,效果良好。初步结案4件。这适用于皮肤损失小于50%的病例。其余病例采用阴部股皮瓣重建。重建病例采用双阴部股皮瓣(4例)和单侧阴部股皮瓣(4例)覆盖。随访时间延长至16个月。结论:阴囊推进皮瓣具有良好的皮肤弹性,适合于修复中小型阴囊缺损。阴部股皮瓣是修复阴囊大面积缺损的有效方法。
{"title":"Coverage of the scrotum after Fournier's gangrene.","authors":"Ahmed Hassan El-Sabbagh","doi":"10.3205/iprs000121","DOIUrl":"https://doi.org/10.3205/iprs000121","url":null,"abstract":"<p><p><b>Background:</b> Fournier's gangrene is a necrotizing fasciitis caused by mixed aerobic and anaerobic bacteria and results in loss of skin and subcutaneous tissue in the perineal area. Coverage of testis varies from closure of the defect primarily, burying inside the thigh, using the remnants of the scrotum for tissue expansion and coverage by flaps. In this manuscript, scrotal advancement flaps and pudendal thigh flaps were used for coverage of the testis unilaterally or bilaterally according to the size of the defect following Fournier gangrene. <b>Patients and methods:</b> From June 2015 to March 2017, twelve cases were admitted to our department. The patients' ages ranged from 37-59 years and they all had suffered from Fournier's gangrene in the perineal area. <b>Results:</b> Of the twelve cases, two cases showed penile involvement. A skin graft was used for coverage of the penile shaft with excellent take. Four cases were closed primarily. This was applied to cases where loss of skin was less than 50%. The rest of the cases were reconstructed by pudendal thigh flap. The reconstructed cases were covered by bilateral pudendal thigh flap (4 cases) and unilateral pudendal thigh flap (4 cases). The follow-up extended up to 16 months. <b>Conclusion:</b> Scrotal advancement flap was suitable for small and medium size defects due to the elasticity of the scrotal skin. Pudendal thigh flap was efficient for the reconstruction of large defects of the scrotum.</p>","PeriodicalId":43347,"journal":{"name":"GMS Interdisciplinary Plastic and Reconstructive Surgery DGPW","volume":"7 ","pages":"Doc01"},"PeriodicalIF":0.4,"publicationDate":"2018-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3205/iprs000121","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35813553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 8
期刊
GMS Interdisciplinary Plastic and Reconstructive Surgery DGPW
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1