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Medium-term results of the treatment of periprosthetic infection with carbon-coated spacers impregnated with silver 浸银碳包覆垫片治疗假体周围感染的中期结果
Pub Date : 2023-11-10 DOI: 10.17816/2311-2905-7997
Leonid I. Malyuchenko, Nikolay S. Nikolaev, Vadim V. Yakovlev, Elena V. Preobrazhenskaya
The aim of the study to evaluate the antibacterial activity and biological compatibility of alloy coatings based on two-dimensionally ordered linear chain carbon (TDOLCC) and medium-term results of treatment of periprosthetic infection with their use. Materials and Methods. Coatings based on TDOLCC were synthesized using alloying additions like nitrogen (TDOLCC+N) and silver (TDOLCC+Ag) on the surfaces of titanium plates and polystyrene plates by the ion-stimulated carbon condensation in a vacuum. The authors examined the superficial bactericidal activity of the coatings and its resistance to mechanical effects. The rate of formation of microbial biofilms by clinical isolates with multiple and extreme resistance to antibiotics was assessed by staining the samples with a solution of crystal violet. The cytotoxic effect of the coatings was evaluated in relation to the primary culture of fibroblasts and keratinocyte cells of the HaCaT line. Results. The authors observed pronounced superficial bactericidal effect of TDOLCC+Ag coating in respect of microorganisms of several taxonomic groups independently of their resistance to antibacterial drugs. TDOLCC+Ag coating proved capable to completely prevent microbial biofilm formation by antibiotic resistant clinical isolates of S. aureus and P. aeruginosa. Silvercontaining coating demonstrated mechanical resistance and preservation of close to baseline level of superficial bactericidal activity even after lengthy abrasion treatment. TDOLCC based coatings did not cause any cytotoxic effects. Structure of monolayers formed in cavities coated by TDOLCC+N and TDOLCC+Ag was indistinguishable from the monolayers in cavities of control plates. Conclusions. The high anti-film activity of DU LCC+Ag coatings was proved in experiment and clinical practice at the follow-up stage. The use of a spacer with a test coating allows you to quickly eliminate the inflammatory process, significantly reduce the number of relapses of PJI in cases of CS and TB infections, and reduce the number of hospital stay days. Evaluation of the mid-term results of PJI treatment gives grounds to predict active protection of the implant surface from colonization by microorganisms and the formation of microbial biofilms, which, together with drug antibiotic prophylaxis, provides a good therapeutic and prophylactic effect on the recurrence of periprosthetic infection.
本研究的目的是评价基于二维有序线性链碳(TDOLCC)合金涂层的抗菌活性和生物相容性,以及使用该涂层治疗假体周围感染的中期效果。材料与方法。采用离子激发碳在真空中缩合的方法,在钛板和聚苯乙烯板表面添加氮(TDOLCC+N)和银(TDOLCC+Ag)合金,合成了TDOLCC涂层。研究了涂层的表面杀菌活性及其对机械效应的抵抗能力。采用结晶紫染色法对具有多重和极端耐药的临床分离株进行微生物生物膜的形成速率评估。通过对HaCaT系成纤维细胞和角质形成细胞的原代培养,评价了涂层的细胞毒性作用。结果。作者观察到,TDOLCC+Ag涂层对不同种类的微生物具有明显的表面杀菌作用,而不影响其对抗菌药物的耐药性。TDOLCC+Ag涂层能够完全阻止金黄色葡萄球菌和铜绿假单胞菌耐药临床分离株形成微生物生物膜。含银涂层表现出机械阻力和保存接近基线水平的表面杀菌活性,即使经过长时间的磨损处理。基于TDOLCC的涂层没有引起任何细胞毒性作用。TDOLCC+N和TDOLCC+Ag涂层的空腔中形成的单层结构与对照板的空腔中形成的单层结构没有区别。结论。在后续的实验和临床实践中证实了DU LCC+Ag涂层具有较高的抗膜活性。使用带有测试涂层的间隔器可以快速消除炎症过程,显着减少CS和TB感染病例中PJI的复发次数,并减少住院天数。通过对PJI治疗中期结果的评估,可以预测种植体表面对微生物定植的积极保护和微生物生物膜的形成,与药物抗生素预防一起,对假体周围感染的复发具有良好的治疗和预防作用。
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引用次数: 0
SUGGESTIONS FOR INTRODUCING SOME NEW TERMS IN PELVIC AND ACETABULAR SURGERY 骨盆和髋臼手术中引入新术语的建议
Pub Date : 2023-10-25 DOI: 10.17816/2311-2905-15531
Nikita Zadneprovskiy, Pavel A. Ivanov, Vladislav V. Kulikov, Yana B. Vladimirova
Abstract Background. The rapid development of modern surgical methods for the treatment of pelvic bone fractures has revealed the need to develop a new terminological apparatus, since the classical anatomical terminology of the pelvis no longer meets the demands of today's therapeutic and scientific processes. The classical set of anatomical names and landmarks does not allow for a detailed description of all the nuances of injuries and new complex surgical techniques. Aim of the study is to develop names for some parts of the bones of the pelvis and its regions, which to date do not have their own designations, and to propose the developed terms for professional discussion. Material and Methods. We analyzed radiologic and CT studies in 150 patients with pelvic bone injury during 2020-2022. A list of potential new anatomical terms was compiled using a systematic literature review and consultation with leading experts in pelvic surgery. Results. New terms have been developed to designate the pelvic regions and their injuries. Conclusion. The introduction of new anatomical terms into clinical practice helps to improve the accuracy of diagnosis and planning of pelvic surgery. Standardization of terminology also promotes uniformity of approaches and exchange of experience between medical specialists, which contributes to the quality of surgical practice.
摘要# x0D;背景。骨盆骨折的现代外科治疗方法的快速发展表明需要开发一种新的术语装置,因为骨盆的经典解剖学术语不再满足当今治疗和科学进程的要求。经典的解剖名称和标志集不允许对所有损伤的细微差别和新的复杂手术技术进行详细描述。这项研究的目的是为迄今为止没有自己名称的骨盆骨骼的某些部分及其区域制定名称,并提出发展的术语供专业讨论。材料和方法。我们分析了2020-2022年期间150例骨盆骨损伤患者的放射学和CT研究。通过系统的文献回顾和咨询盆腔外科的顶尖专家,我们编制了一份潜在的新解剖学术语清单。 结果。已经发展出新的术语来表示骨盆区域及其损伤。 结论。在临床实践中引入新的解剖学术语有助于提高骨盆手术诊断和计划的准确性。术语的标准化还促进了方法的统一和医学专家之间的经验交流,这有助于提高外科实践的质量。
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 Background. The rapid development of modern surgical methods for the treatment of pelvic bone fractures has revealed the need to develop a new terminological apparatus, since the classical anatomical terminology of the pelvis no longer meets the demands of today's therapeutic and scientific processes. The classical set of anatomical names and landmarks does not allow for a detailed description of all the nuances of injuries and new complex surgical techniques.
 Aim of the study is to develop names for some parts of the bones of the pelvis and its regions, which to date do not have their own designations, and to propose the developed terms for professional discussion.
 Material and Methods. We analyzed radiologic and CT studies in 150 patients with pelvic bone injury during 2020-2022. A list of potential new anatomical terms was compiled using a systematic literature review and consultation with leading experts in pelvic surgery.
 Results. New terms have been developed to designate the pelvic regions and their injuries.
 Conclusion. The introduction of new anatomical terms into clinical practice helps to improve the accuracy of diagnosis and planning of pelvic surgery. Standardization of terminology also promotes uniformity of approaches and exchange of experience between medical specialists, which contributes to the quality of surgical practice.","PeriodicalId":43463,"journal":{"name":"Travmatologiya i ortopediya Rossii","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135113587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correction of multiapical deformities of the lower libs: Review 下肢多根尖畸形的矫正:综述
Pub Date : 2023-10-18 DOI: 10.17816/2311-2905-11174
Evgeniy Sergeevich Golovenkin, Leonid Nikolaevich Solomin
Relevance Multiapical deformities (MD) of the lower limbs - there're hard and widespread orthopedic pathology. Unfortunaly, there're not found any works with a comprehensive assessment of modern views on the problem of treating patients with multiapical deformities of long bones. Purpose. Using the world literature, to identify the modern position, problems and prospectives of the correction of multialical deformities of the lower limbs. Methods. PubMed, SAGE Publishing Journals, Embase, MEDLINE, eLIBRARY, КиберЛенинка, Google Scholar resources were used. At analyzis several criterial were used: diagnostic, planning and approaches of correction of the multiapical deformities. Results. Terms "multiapical deformity" and "multilevel deformity" used as a synonymes. At the same time, term "multilevel deformity" is used to refer to uniapical deformities of different limb segments. The main diagnostic sign of multiapical deformity is the location of the apex outside the bone. In MD planning uses the axis of the middle/intermediate fragment(s). Most authors define it as the middiaphyseal line. Correction of multiapical deformities can be realyzed acute or gradual. Acute correction is more comfortable for the patient. If there are contraindications, it's performed gradually using "Ilizarov hinges" or orthopedic hexapods. Conclusion. Term "multiapical deformity" is more correct for using to definity the researced pathology. The main diagnostic sign of MD is not absolute and requires clarification. When planning a correction, there are difficulties in the case of using mechanical axes, as well as when it is necessary to determine the axis of a non-linear middle fragment. The "spring technique" of using an orthopedic hexapod has significant advantages, but it's necessary to clarification the optimal characteristics of the elastic rods (springs), the points of their fixation to the frame and method of using the hexapod computer program. The solution of these problems will improve the efficiency of treatment of patients with multiapical deformities.
下肢多根尖畸形(MD)是一种顽固而广泛的骨科病理学。遗憾的是,目前还没有发现任何对治疗长骨多尖畸形问题的现代观点进行全面评估的著作。 目的。结合国内外文献资料,探讨下肢多关节畸形矫治的现状、存在的问题及发展前景。 方法。使用了PubMed, SAGE Publishing Journals, Embase, MEDLINE, eliberary, КиберЛенинка, Google Scholar等资源。分析采用了多尖畸形的诊断、计划和矫治方法;结果。术语“多根尖畸形”和“多级畸形”用作同义词。同时,“多节段畸形”一词是指不同肢体节段的单根尖畸形。多根尖畸形的主要诊断标志是根尖在骨外的位置。在MD中,规划使用中间/中间碎片的轴。大多数作者将其定义为骨干中线。多根尖畸形的矫正可分急性或渐进式两种。急性矫正对病人来说更舒服。如果有禁忌症,则逐步使用“伊利扎罗夫铰链”或矫形六足。结论。用“多根尖畸形”一词来定义所研究的病理更为正确。MD的主要诊断标志不是绝对的,需要澄清。在规划校正时,在使用机械轴的情况下,以及在需要确定非线性中间碎片的轴时,存在困难。使用矫形六足的“弹簧技术”具有明显的优势,但有必要明确弹性杆(弹簧)的最佳特性、与框架的固定点以及六足计算机程序的使用方法。这些问题的解决将提高多尖畸形患者的治疗效率。
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 Purpose. Using the world literature, to identify the modern position, problems and prospectives of the correction of multialical deformities of the lower limbs.
 Methods. PubMed, SAGE Publishing Journals, Embase, MEDLINE, eLIBRARY, КиберЛенинка, Google Scholar resources were used. At analyzis several criterial were used: diagnostic, planning and approaches of correction of the multiapical deformities.
 Results. Terms \"multiapical deformity\" and \"multilevel deformity\" used as a synonymes. At the same time, term \"multilevel deformity\" is used to refer to uniapical deformities of different limb segments. The main diagnostic sign of multiapical deformity is the location of the apex outside the bone. In MD planning uses the axis of the middle/intermediate fragment(s). Most authors define it as the middiaphyseal line. Correction of multiapical deformities can be realyzed acute or gradual. Acute correction is more comfortable for the patient. If there are contraindications, it's performed gradually using \"Ilizarov hinges\" or orthopedic hexapods.
 Conclusion. Term \"multiapical deformity\" is more correct for using to definity the researced pathology. The main diagnostic sign of MD is not absolute and requires clarification. When planning a correction, there are difficulties in the case of using mechanical axes, as well as when it is necessary to determine the axis of a non-linear middle fragment. The \"spring technique\" of using an orthopedic hexapod has significant advantages, but it's necessary to clarification the optimal characteristics of the elastic rods (springs), the points of their fixation to the frame and method of using the hexapod computer program. The solution of these problems will improve the efficiency of treatment of patients with multiapical deformities.","PeriodicalId":43463,"journal":{"name":"Travmatologiya i ortopediya Rossii","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135884588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of Zweymüller Stem Modification on Clinical and Radiological Outcomes zweymller干细胞改良对临床和放射预后的影响
Pub Date : 2023-09-15 DOI: 10.17816/2311-2905-13226
Aymen Riahi, Igor I. Shubnyakov, Andrei P. Sereda, Mahomed A. Cherkasov, Ilhom E. Khujanazarov, Rashid M. Tikhilov
Background. According to the analysis of large arthroplasty registers we have noted the increase in the use of non-cemented implants, because the latter shows the same results of implant survival as well as cemented implants. On the other hand, they can affect the quality of the bone around the implant in different ways. These components differ in shape, length, and surface properties. According to the analysis of the arthroplasty register of the Vreden National Medical Research Center of Traumatology and Orthopedics, a significant decrease of the Alloclassic femoral stem using can be noted. In parallel the use of its SL-PLUS MIA modification has increased significantly. Aims of the study: 1) to determine the influence of changes in the design of the Zweymller-type femoral stem on midterm and long-term outcomes and its survival; 2) to identify the characteristics of adaptive remodeling of periprosthetic bone tissue around these femoral stems; 3) to determine risk factors for aseptic loosening of these femoral stems. Methods. 492 cases of hip arthroplasty using the Alloclassic and SL-PLUS MIA femoral stems were observed, with an average follow-up 78.6 months. The patients were divided into 2 groups according to the type of femoral stem. The assessment the hip articulation condition was carried out using the HHS and OHS. The intensity of the pain syndrome was assessed by VAS, and the level of patients satisfaction. The dynamic analysis of X-rays was also performed visually. Results. A significant improvement in clinical and functional results was observed according to the HHS and OHS in both groups of patients, regardless of the type of femoral stem. Analysis of X-rays over time showed differences in the behavior of these two femoral component models. The radiolucent lines around the femoral stem are absent in SL-PLUS MIA group, in Alloclassic stem group radiolucent lines are present even at a minimal period (12 months). We also found that a tight fit of Zweymller femoral stems in the distal shaft is a risk factor for severe stress-shielding syndrome, especially in the funnel channels. But ceteris paribus, a distal tight fit of SL-PLUS MIA stems despite similar geometry of the distal part does not lead to such frequent manifestation of severe stress shielding. Conclusion. The change in Zweymller stem design from Alloclassic to SL-PLUS MIA improved the nature of adaptive remodeling in the periprosthetic area of the femur. It may improve the long-term results of primary hip arthroplasty, but these differences require closer observation.
背景。根据对大关节置换术登记的分析,我们注意到非骨水泥假体使用的增加,因为后者显示出与骨水泥假体相同的假体存活结果。另一方面,它们会以不同的方式影响种植体周围骨骼的质量。这些部件的形状、长度和表面特性各不相同。根据Vreden国家创伤与骨科医学研究中心关节置换术登记的分析,可以注意到异位股骨干使用的显著减少。与此同时,其SL-PLUS MIA改型的使用也显著增加。 研究目的:1)确定zweymler型股骨干设计的改变对中期和长期预后及其生存期的影响;2)确定股骨干周围假体周围骨组织的适应性重构特征;3)确定无菌性股骨干松动的危险因素。 方法:对492例采用同种异体和SL-PLUS MIA股骨干进行髋关节置换术的患者进行观察,平均随访78.6个月。根据股骨干类型将患者分为两组。采用HHS和OHS对髋关节关节状况进行评估。采用VAS评估疼痛综合征的强度,并对患者的满意度进行评估。x射线的动态分析也进行了目测。 结果。无论股骨干类型如何,两组患者根据HHS和OHS观察到临床和功能结果的显著改善。随着时间的推移,x射线分析显示这两种股骨成分模型的行为存在差异。在SL-PLUS MIA组中,股干周围没有放射透光线,而在异源性股干组中,即使在最短的时间(12个月)也有放射透光线。我们还发现,zweymler股干在远端轴的紧密配合是严重应力屏蔽综合征的危险因素,特别是在漏斗通道中。但在其他条件相同的情况下,尽管远端几何形状相似,但SL-PLUS MIA茎的远端紧密配合不会导致如此频繁的严重应力屏蔽现象。 结论。从Alloclassic到SL-PLUS MIA的zweymler柄设计的改变改善了股骨假体周围区域适应性重构的性质。它可能改善原发性髋关节置换术的长期效果,但这些差异需要更密切的观察。
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 Aims of the study: 1) to determine the influence of changes in the design of the Zweymller-type femoral stem on midterm and long-term outcomes and its survival; 2) to identify the characteristics of adaptive remodeling of periprosthetic bone tissue around these femoral stems; 3) to determine risk factors for aseptic loosening of these femoral stems.
 Methods. 492 cases of hip arthroplasty using the Alloclassic and SL-PLUS MIA femoral stems were observed, with an average follow-up 78.6 months. The patients were divided into 2 groups according to the type of femoral stem. The assessment the hip articulation condition was carried out using the HHS and OHS. The intensity of the pain syndrome was assessed by VAS, and the level of patients satisfaction. The dynamic analysis of X-rays was also performed visually.
 Results. A significant improvement in clinical and functional results was observed according to the HHS and OHS in both groups of patients, regardless of the type of femoral stem. Analysis of X-rays over time showed differences in the behavior of these two femoral component models. The radiolucent lines around the femoral stem are absent in SL-PLUS MIA group, in Alloclassic stem group radiolucent lines are present even at a minimal period (12 months). We also found that a tight fit of Zweymller femoral stems in the distal shaft is a risk factor for severe stress-shielding syndrome, especially in the funnel channels. But ceteris paribus, a distal tight fit of SL-PLUS MIA stems despite similar geometry of the distal part does not lead to such frequent manifestation of severe stress shielding.
 Conclusion. The change in Zweymller stem design from Alloclassic to SL-PLUS MIA improved the nature of adaptive remodeling in the periprosthetic area of the femur. It may improve the long-term results of primary hip arthroplasty, but these differences require closer observation.","PeriodicalId":43463,"journal":{"name":"Travmatologiya i ortopediya Rossii","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135486679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A CLINICAL CASE OF IMPACT BONE PLASTY IN THE REPLACEMENT OF DEFECTS IN THE ACETABULUM AND FEMORAL COMPONENT DURING REVISION HIP ENDOPROSTHETICS 冲击骨成形术置换髋臼及股骨假体缺损一例
Pub Date : 2023-09-15 DOI: 10.17816/2311-2905-8008
Irina Kirilova, Vadim N. Golnik, Vladimir Peleganchuk, Yuriy Batrak, Vitaliy Pavlov
Background. For many years, the main reasons for revision surgeries after hip arthroplasty remain aseptic loosening and osteolysis, which lead to formation of bone defects of various size and localization. Given the relatively young age of patients undergoing revision, the methods of biological restoration of the bone tissue, such as impaction bone grafting (IBG), are of particular interest. Aim of the report to demonstrate the delayed outcome of impaction bone grafting using compacted morselized bone allograft. Case presentation. Complicated clinical case of a 62-year-old patient with Paprosky type IIA bone deficiency in the acetabulum and Paprosky type II bone deficiency in the proximal femur with aseptic loosening of the acetabular and femoral components of the hip prosthesis is presented. During revision arthroplasty with cemented components, IBG of the acetabulum and femur was performed with a reconstructive mesh augmentation of the acetabulum using Stryker X-Change technology. Bone allograft prepared with the use of heat disinfection method served as an osteoplastic material. Follow-up period was 4 years. Control X-rays demonstrate restoration of the center of rotation of the hip, presence of bone masses in the areas of pelvic and femoral bone defects, absence of osteoplastic material resorption and migration of implants during the follow-up period. Clinical assessment shows an improvement of the Harris Hip Score from 34 to 85 points. Conclusion. Obtained results showed the efficacy of impaction bone grafting with the bone allograft prepared with the use of heat disinfection method in the mid-term period.
背景。多年来,髋关节置换术后翻修手术的主要原因仍然是无菌性松动和骨溶解,导致不同大小和定位的骨缺损的形成。考虑到接受翻修的患者相对年轻,骨组织的生物修复方法,如嵌塞骨移植(IBG),是特别感兴趣的。该报告的目的是证明使用压实的碎片化同种异体骨移植的嵌塞骨移植的延迟结果。案例演示。本文报道了一名62岁患者髋臼和股骨近端存在帕普洛斯基IIA型缺骨症,伴无菌性髋臼和股骨假体松动的复杂临床病例。在使用骨水泥假体翻修关节成形术期间,使用Stryker X-Change技术对髋臼进行重建网状物增强,对髋臼和股骨进行IBG。采用热消毒法制备的同种异体骨移植物作为成骨材料。随访4年。对照x光片显示髋关节旋转中心恢复,骨盆和股骨骨缺损区域存在骨团块,在随访期间没有骨塑材料吸收和植入物迁移。临床评估显示Harris髋关节评分从34分提高到85分。结论。结果表明,采用热消毒法制备的同种异体骨移植中期嵌塞植骨效果良好。
{"title":"A CLINICAL CASE OF IMPACT BONE PLASTY IN THE REPLACEMENT OF DEFECTS IN THE ACETABULUM AND FEMORAL COMPONENT DURING REVISION HIP ENDOPROSTHETICS","authors":"Irina Kirilova, Vadim N. Golnik, Vladimir Peleganchuk, Yuriy Batrak, Vitaliy Pavlov","doi":"10.17816/2311-2905-8008","DOIUrl":"https://doi.org/10.17816/2311-2905-8008","url":null,"abstract":"Background. For many years, the main reasons for revision surgeries after hip arthroplasty remain aseptic loosening and osteolysis, which lead to formation of bone defects of various size and localization. Given the relatively young age of patients undergoing revision, the methods of biological restoration of the bone tissue, such as impaction bone grafting (IBG), are of particular interest.
 Aim of the report to demonstrate the delayed outcome of impaction bone grafting using compacted morselized bone allograft.
 Case presentation. Complicated clinical case of a 62-year-old patient with Paprosky type IIA bone deficiency in the acetabulum and Paprosky type II bone deficiency in the proximal femur with aseptic loosening of the acetabular and femoral components of the hip prosthesis is presented. During revision arthroplasty with cemented components, IBG of the acetabulum and femur was performed with a reconstructive mesh augmentation of the acetabulum using Stryker X-Change technology. Bone allograft prepared with the use of heat disinfection method served as an osteoplastic material. Follow-up period was 4 years. Control X-rays demonstrate restoration of the center of rotation of the hip, presence of bone masses in the areas of pelvic and femoral bone defects, absence of osteoplastic material resorption and migration of implants during the follow-up period. Clinical assessment shows an improvement of the Harris Hip Score from 34 to 85 points.
 Conclusion. Obtained results showed the efficacy of impaction bone grafting with the bone allograft prepared with the use of heat disinfection method in the mid-term period.","PeriodicalId":43463,"journal":{"name":"Travmatologiya i ortopediya Rossii","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135353407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
ORTHOPEDICS IN THE FOCUS OF INTELLECTUAL PROPERTY 骨科中的重点知识产权
Pub Date : 2023-09-15 DOI: 10.17816/2311-2905-15522
Tatyana Nikolayevna Erivantseva, Svetlana Yurievna Tuzova, Nikolay Borisovich Lyskov, Yulia Valeryevna Blokhina, Anna Andreevna Isamova
High incidence of injuries, diseases of musculoskeletal system and connective tissue leads to a high demand for modern high-tech materials in the area of orthopedics and traumatology. Development of russian materials is an extremely relevant issue, especially under conditions of restricted supply of foreign products to the Russian Federation. Creation of new products and their subsequent launch to the market require comprehensive protection of unique information about the design, composition or production/manufacturing technology of the product. Analysis of patenting domestic solutions for trauma and orthopedic surgery in the Russian Federation has shown that there are various risks associated with the commercialization of national products. For example, russian developers in a number of cases neglect patent protection of their developments, which puts successful developments at risk of unauthorized copying or claims from other market players. On the other hand, patenting strategy of domestic developers for their products in most cases contains a number of errors, such as narrow bounds of patent protection due to incorrectly drafted patent claims. For example, these can be in formulations that can be easily bypassed in case of commercial interest in the product, preferential patenting of technological processes, lack of comprehensive patent protection of the product. Such patenting errors make the development unattractive for investors and manufacturers, which leads to low commercializability of russian inventions. Thus, russian developers, who have significant scientific potential and competencies to create highly effective national products, do not proceed with technology transfer and cannot bring their promising and in-demand products to the market.
损伤、肌肉骨骼系统疾病和结缔组织疾病的高发导致了骨科和创伤学领域对现代高科技材料的高需求。开发俄罗斯材料是一个极其重要的问题,特别是在限制向俄罗斯联邦供应外国产品的情况下。新产品的创造及其随后的市场投放需要全面保护有关产品的设计,组成或生产/制造技术的独特信息。对俄罗斯联邦创伤和整形外科国内解决办法申请专利情况的分析表明,与本国产品商业化有关的各种风险。例如,在许多情况下,俄罗斯开发商忽视了对其开发项目的专利保护,这使得成功的开发项目面临被其他市场参与者未经授权复制或索赔的风险。另一方面,国内开发商对其产品的专利策略在大多数情况下存在许多错误,例如由于专利权利要求书的起草不正确而导致专利保护范围狭窄。例如,在产品具有商业利益、优先授予技术工艺专利、缺乏对产品的全面专利保护的情况下,这些可以在配方中轻易绕过。这种专利错误使得发展对投资者和制造商没有吸引力,这导致了俄罗斯发明的低商业化。因此,具有巨大的科学潜力和能力来创造高度有效的民族产品的俄罗斯开发人员不进行技术转让,也无法将其有希望和有需求的产品推向市场。
{"title":"ORTHOPEDICS IN THE FOCUS OF INTELLECTUAL PROPERTY","authors":"Tatyana Nikolayevna Erivantseva, Svetlana Yurievna Tuzova, Nikolay Borisovich Lyskov, Yulia Valeryevna Blokhina, Anna Andreevna Isamova","doi":"10.17816/2311-2905-15522","DOIUrl":"https://doi.org/10.17816/2311-2905-15522","url":null,"abstract":"High incidence of injuries, diseases of musculoskeletal system and connective tissue leads to a high demand for modern high-tech materials in the area of orthopedics and traumatology. Development of russian materials is an extremely relevant issue, especially under conditions of restricted supply of foreign products to the Russian Federation. Creation of new products and their subsequent launch to the market require comprehensive protection of unique information about the design, composition or production/manufacturing technology of the product. Analysis of patenting domestic solutions for trauma and orthopedic surgery in the Russian Federation has shown that there are various risks associated with the commercialization of national products. For example, russian developers in a number of cases neglect patent protection of their developments, which puts successful developments at risk of unauthorized copying or claims from other market players. On the other hand, patenting strategy of domestic developers for their products in most cases contains a number of errors, such as narrow bounds of patent protection due to incorrectly drafted patent claims. For example, these can be in formulations that can be easily bypassed in case of commercial interest in the product, preferential patenting of technological processes, lack of comprehensive patent protection of the product. Such patenting errors make the development unattractive for investors and manufacturers, which leads to low commercializability of russian inventions. Thus, russian developers, who have significant scientific potential and competencies to create highly effective national products, do not proceed with technology transfer and cannot bring their promising and in-demand products to the market.","PeriodicalId":43463,"journal":{"name":"Travmatologiya i ortopediya Rossii","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135352939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Coracoid Process Fracture Associated With a Distal Clavicle Fracture: A Case Report 喙突骨折合并锁骨远端骨折1例
Pub Date : 2023-09-15 DOI: 10.17816/2311-2905-14793
Alexander I. Avdeev, Dmitrii G. Parfeev, Danil D Parshin, Ekaterina V. Sinitsyna
Background. Fracture of the distal clavicle fracture associated with a coracoid process fracture is extremely rare in the practice of an orthopedic surgeon. Therefore, there is no common approach to the treatment of patients with this type of bone injuries of the shoulder girdle. Aim of the study to demonstrate positive experience of conservative treatment of the coracoid process fracture combined with hook plate fixation for distal clavicle fracture. Case presentation. We present a rare clinical case of a closed distal clavicle fracture associated with coracoid process fracture. Trauma occurred when the patient fell down the stairs on his abducted upper limb. After examination, the distal clavicle fracture was fixed with a hook plate. Intraoperatively, X-rays showed a satisfactory position of the coracoid process of the scapula. Therefore, it was decided not to fix it additionally. CT scans three months after the surgery showed bone fragments consolidation. Removal of the hook plate and screws from the clavicle was performed. Conclusion. Presented clinical case illustrates successful treatment result of this type of fractures without fixation of the coracoid process fracture. The hook plating allows to stabilize bone fragments and restore ligament tension, which makes this implant non-alternative for fixation of this type of injuries.
背景。锁骨远端骨折合并喙突骨折在骨科手术中极为罕见。因此,对于这类肩带骨损伤患者的治疗尚无统一的方法。 目的探讨保守治疗喙突骨折联合钩钢板内固定治疗锁骨远端骨折的积极经验。案例演示。我们报告一例罕见的锁骨远端闭合性骨折合并喙突骨折的临床病例。创伤发生在病人从楼梯上摔下来,上肢外展。检查后,用钩钢板固定锁骨远端骨折。术中x光片显示肩胛骨喙突位置良好。因此,我们决定不再修复它。术后3个月的CT扫描显示骨碎片巩固。从锁骨上取下钩板和螺钉。 结论。本文的临床病例说明了这种类型的喙突骨折无固定治疗的成功效果。钩状钢板可以稳定骨碎片并恢复韧带张力,这使得该植入物不可替代地固定这类损伤。
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 Aim of the study to demonstrate positive experience of conservative treatment of the coracoid process fracture combined with hook plate fixation for distal clavicle fracture.
 Case presentation. We present a rare clinical case of a closed distal clavicle fracture associated with coracoid process fracture. Trauma occurred when the patient fell down the stairs on his abducted upper limb. After examination, the distal clavicle fracture was fixed with a hook plate. Intraoperatively, X-rays showed a satisfactory position of the coracoid process of the scapula. Therefore, it was decided not to fix it additionally. CT scans three months after the surgery showed bone fragments consolidation. Removal of the hook plate and screws from the clavicle was performed.
 Conclusion. Presented clinical case illustrates successful treatment result of this type of fractures without fixation of the coracoid process fracture. The hook plating allows to stabilize bone fragments and restore ligament tension, which makes this implant non-alternative for fixation of this type of injuries.","PeriodicalId":43463,"journal":{"name":"Travmatologiya i ortopediya Rossii","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135353433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Syndromic assessment of degenerative disorders of the lumbar spine in elderly patients 老年患者腰椎退行性疾病的综合征评估
Pub Date : 2023-09-15 DOI: 10.17816/2311-2905-12024
Vladimir Klimov, Roman Khalepa, Evgeniya Amelina, Alexei Evsukov, Alexei Krivoshapkin, Sergei Ryabykh
Background. The choice of the method and options for surgical treatment of degenerative pathology of the lumbar spine is difficult due to the lack of clear clinical and radiological criteria for diagnosis and a direct correlation between the severity of the radiological manifestations of the disease and clinical symptoms. The aim of this study was to analyze the clinical and neurological characteristics of elderly patients with degenerative disorders of the lumbar spine and to identify the dominant clinical and radiologic syndromes. Methods. Сohort of 1013 patients were operated using MIS technologies (decompression alone, TLIF, LLIF, ALIF) in the period 20132017 (367 male/646 female). The age range is 60-89 years (mean 66 years). The criteria for identifying the leading syndromes: leg pain/back pain with a threshold value of 5 points according to VAS, X-ray criteria for clinical instability by A.A. White and M.M. Panjabi (value 5 points), Cobb angle 10, markers of sagittal imbalance: Index Barrey (II and III), PT increase above target values, L4-S1 and LL deficiency. Results. Symptoms of compression were identified in 97% of patients. Radiculopathy syndrome was detected in 665 (66%) patients with mean leg pain 7 points, neurogenic intermittent claudication in 319 (31%) patients. Degenerative spondylolisthesis according to radiological criteria was detected in 428 (42%) patients. Degenerative scoliotic deformity had 91 (9%) patients. In accordance with the proposed criteria, the dominant compression syndrome was determined in 624 patients (62%), clinical instability syndrome in 338 (33%), deformity syndrome with sagittal imbalance in 51 (5%). Conclusion. Syndromic assessment of clinical, neurological and radiological manifestations of degenerative disorders provides the possibility of identifying the dominant syndrome requiring operative surgical treatment and a differentiated approach to choosing the optimal surgical option.
背景。由于缺乏明确的临床和影像学诊断标准,以及疾病放射表现的严重程度与临床症状之间的直接相关性,腰椎退行性病理的手术治疗方法和选择是困难的。 本研究的目的是分析老年腰椎退行性疾病患者的临床和神经学特征,并确定主要的临床和影像学综合征。 方法。2013 - 2017年,1013例患者采用MIS技术(单独减压、TLIF、LLIF、ALIF)进行手术(男性367例/女性646例)。年龄范围60-89岁(平均66岁)。主要症状的识别标准:VAS阈值为5分的腿痛/腰痛,A.A. White和M.M. Panjabi的临床不稳定x线标准(值5分),Cobb角10,矢状面失衡指标:Index Barrey (II和III), PT高于目标值,L4-S1和LL不足。 结果。97%的患者有压迫症状。665例(66%)患者出现神经根病综合征,平均腿痛7分,319例(31%)患者出现神经源性间歇性跛行。428例(42%)患者根据放射学标准检测到退行性脊柱滑脱。退行性脊柱侧凸畸形91例(9%)。根据提出的标准,624例(62%)患者被确定为压迫综合征,338例(33%)患者被确定为临床不稳定综合征,51例(5%)患者被确定为矢状面不平衡畸形综合征。结论。对退行性疾病的临床、神经学和放射学表现进行综合征评估,为确定需要手术治疗的显性综合征提供了可能性,并为选择最佳手术方案提供了差异化的方法。
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 The aim of this study was to analyze the clinical and neurological characteristics of elderly patients with degenerative disorders of the lumbar spine and to identify the dominant clinical and radiologic syndromes.
 Methods. Сohort of 1013 patients were operated using MIS technologies (decompression alone, TLIF, LLIF, ALIF) in the period 20132017 (367 male/646 female). The age range is 60-89 years (mean 66 years). The criteria for identifying the leading syndromes: leg pain/back pain with a threshold value of 5 points according to VAS, X-ray criteria for clinical instability by A.A. White and M.M. Panjabi (value 5 points), Cobb angle 10, markers of sagittal imbalance: Index Barrey (II and III), PT increase above target values, L4-S1 and LL deficiency.
 Results. Symptoms of compression were identified in 97% of patients. Radiculopathy syndrome was detected in 665 (66%) patients with mean leg pain 7 points, neurogenic intermittent claudication in 319 (31%) patients. Degenerative spondylolisthesis according to radiological criteria was detected in 428 (42%) patients. Degenerative scoliotic deformity had 91 (9%) patients. In accordance with the proposed criteria, the dominant compression syndrome was determined in 624 patients (62%), clinical instability syndrome in 338 (33%), deformity syndrome with sagittal imbalance in 51 (5%).
 Conclusion. Syndromic assessment of clinical, neurological and radiological manifestations of degenerative disorders provides the possibility of identifying the dominant syndrome requiring operative surgical treatment and a differentiated approach to choosing the optimal surgical option.","PeriodicalId":43463,"journal":{"name":"Travmatologiya i ortopediya Rossii","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135354147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sergei P. Mironov 谢尔盖-P-米罗诺夫
Pub Date : 2023-09-15 DOI: 10.17816/2311-2905-16491
Irina V. Kolesnikova
14 августа 2023 г. на 76-м году жизни после не продолжительной болезни скоропостижно скончался выдающийся ученый, отличный организатор, прекрасный клиницист, эрудированный педагог, общественный деятель, доктор медицинских наук, профессор, академик РАН Сергей Павлович Миронов.
2023年8月14日,一位杰出的科学家、杰出的组织者、杰出的临床学家、博学的教育家、社会工作者、医学博士、教授、教授、学者谢尔盖·帕夫洛维奇·米罗诺夫突然去世。
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引用次数: 0
Knee arthroplasty in real clinical practice: analysis of 36,350 cases from the register of the Vreden National Medical Center of Trauma and Ortopedics 真实临床实践中的膝关节置换术:对来自弗莱登国家创伤骨科医学中心登记的36,350例病例的分析
Pub Date : 2023-09-15 DOI: 10.17816/2311-2905-9349
Petr Preobrazhensky, Alexey Fil, Nikolay Kornilov, Alexander Panteleev, Maksim Guatsaev, Alexander Kazemirsky, Andrey V Mazurenko, Andrey Sereda
Background.Nowadays the knee arthroplasty register of the Vreden National Medical Research Center of Traumatology and Orthopedics (hereinafter referred to as the Vreden Center) contains clinical and statistical data on more than 39,000 primary and revision knee replacements, that mimics current state of this kind of surgery in Russia. Aimofthestudy to analyze the last decade trends in primary knee arthroplasty in largest Russian arthroplasty center. Methods.Data were obtained from the register of the Vreden Center for the period from 2011 to 2022. Information on knee arthroplasty included epidemiologic and numerous peri-operative data including type of surgery and implant, degree of constrain, primary patella resurfacing etc. Resultsanddiscussion.From 2011 to 2022, 36,350 (92.3%) primary arthroplasties performed at the Vreden Center. The number of interventions increased more than twice: from 1,678 in 2011 to 3,924 in 2022. Similar trends observed in Australia and Sweden, where the number of knee arthroplasties increased by 8.2% and 8% in 2021 compared to 2020, respectively. The frequency of primary patellar resurfacing at the Vreden Center was 2.2% over the entire period of observation. On the contrary, the rate of patella replacement increased from 41% in 2005 to 76.1% in 2021 in Australia and from 24.4% in 2015 to 31.9% in 2020 in Switzerland. The partial knee arthroplasty showed enormous growth more than 14 times: from 0.3% in 2011 to 4.3% in 2022 at the Vreden Center. Worldwide unicompartmental knee replacement is still less popular than total and its number widely varies: 4.2% in the USA, 6.9% in Australia, 9.2% in Canada, 11.9% in Norway, 12.8% in Sweden, and 18.4% in Switzerland. Posterior cruciate ligament (PCL) retaining total knee arthroplasties (TKA) prevailed at the Vreden Center: 68.3%, while in other countries it utilize even more widely: 70.5% in Norway, 75% in New Zealand and 93.5% in Sweden. The total length of hospital stay (LOS) decreased dramatically from 19.6 in 2011 to 8.6 in 2022 at the Vreden Center. Nevertheless, there are still opportunities to improve it: by the way in Canada the average LOS for TKA is 2.3 and the USA 0.8 and 1.7 for partial and total arthroplasty, respectively. Conclusion.The main current trends of knee arthroplasty in Russia are the following: increase the number of surgeries, reduced LOS, TKA without patella resurfacing and with PCL retention, finally the growth of partial knee arthroplasties.
背景。如今,Vreden国家创伤和骨科医学研究中心(以下简称Vreden中心)的膝关节置换术登记册包含了超过39,000例初级和翻修膝关节置换术的临床和统计数据,这些数据模仿了俄罗斯此类手术的现状。本研究旨在分析俄罗斯最大的关节置换术中心近十年来初级膝关节置换术的趋势。 方法。数据来自弗里登中心2011年至2022年期间的登记册。关于膝关节置换术的信息包括流行病学和大量围手术期数据,包括手术类型和植入物、约束程度、原发性髌骨置换等 Resultsanddiscussion。从2011年到2022年,在弗里登中心进行了36,350例(92.3%)初级关节置换术。干预措施的数量增加了一倍多:从2011年的1678项增加到2022年的3924项。澳大利亚和瑞典也出现了类似的趋势,与2020年相比,2021年膝关节置换术的数量分别增加了8.2%和8%。在整个观察期间,在Vreden中心进行髌骨置换的频率为2.2%。相反,澳大利亚髌骨置换率从2005年的41%上升到2021年的76.1%,瑞士从2015年的24.4%上升到2020年的31.9%。在弗雷登中心,部分膝关节置换术的比例从2011年的0.3%增长到2022年的4.3%,增长了14倍以上。在世界范围内,单室膝关节置换术仍然不如全室膝关节置换术流行,其数量差异很大:美国4.2%,澳大利亚6.9%,加拿大9.2%,挪威11.9%,瑞典12.8%,瑞士18.4%。后交叉韧带(PCL)保留全膝关节置换术(TKA)在弗里登中心盛行:68.3%,而在其他国家则更为广泛:挪威为70.5%,新西兰为75%,瑞典为93.5%。弗莱登中心的总住院时间(LOS)从2011年的19.6急剧下降到2022年的8.6。然而,仍有改进的机会:顺便说一下,在加拿大,TKA的平均LOS为2.3,而美国部分和全关节置换术的平均LOS分别为0.8和1.7。结论。目前俄罗斯膝关节置换术的主要趋势是:手术次数增加,LOS降低,TKA不髌骨表面置换,PCL保留,最后是部分膝关节置换术的增长。
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 Aimofthestudy to analyze the last decade trends in primary knee arthroplasty in largest Russian arthroplasty center.
 Methods.Data were obtained from the register of the Vreden Center for the period from 2011 to 2022. Information on knee arthroplasty included epidemiologic and numerous peri-operative data including type of surgery and implant, degree of constrain, primary patella resurfacing etc.
 Resultsanddiscussion.From 2011 to 2022, 36,350 (92.3%) primary arthroplasties performed at the Vreden Center.
 The number of interventions increased more than twice: from 1,678 in 2011 to 3,924 in 2022. Similar trends observed in Australia and Sweden, where the number of knee arthroplasties increased by 8.2% and 8% in 2021 compared to 2020, respectively. The frequency of primary patellar resurfacing at the Vreden Center was 2.2% over the entire period of observation. On the contrary, the rate of patella replacement increased from 41% in 2005 to 76.1% in 2021 in Australia and from 24.4% in 2015 to 31.9% in 2020 in Switzerland. The partial knee arthroplasty showed enormous growth more than 14 times: from 0.3% in 2011 to 4.3% in 2022 at the Vreden Center. Worldwide unicompartmental knee replacement is still less popular than total and its number widely varies: 4.2% in the USA, 6.9% in Australia, 9.2% in Canada, 11.9% in Norway, 12.8% in Sweden, and 18.4% in Switzerland. Posterior cruciate ligament (PCL) retaining total knee arthroplasties (TKA) prevailed at the Vreden Center: 68.3%, while in other countries it utilize even more widely: 70.5% in Norway, 75% in New Zealand and 93.5% in Sweden.
 The total length of hospital stay (LOS) decreased dramatically from 19.6 in 2011 to 8.6 in 2022 at the Vreden Center. Nevertheless, there are still opportunities to improve it: by the way in Canada the average LOS for TKA is 2.3 and the USA 0.8 and 1.7 for partial and total arthroplasty, respectively.
 Conclusion.The main current trends of knee arthroplasty in Russia are the following: increase the number of surgeries, reduced LOS, TKA without patella resurfacing and with PCL retention, finally the growth of partial knee arthroplasties.","PeriodicalId":43463,"journal":{"name":"Travmatologiya i ortopediya Rossii","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135352779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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Travmatologiya i ortopediya Rossii
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