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3-Layer Immunoperoxidase Protocol Reaction, Endomucin, and Alpha-smooth Muscle Actin Detection 三层免疫过氧化物酶方案反应,内啡肽和α -平滑肌肌动蛋白检测
Pub Date : 2022-04-07 DOI: 10.47705/kjdmr.216110
Rukaia Sheneeb, Fawzia Takala
Background and objectives. Immunohistochemistry (IHC) is the detection of antigens in tissue sections by specific antibodies. It has the unique advantage over other methods for detection proteins like α-Smooth Muscle Actin and endomucin, enabling the correlation of antigens with their location within a tissue. The aim of the study was to identify α-SMA and endomucin in cardiac muscle tissue and arterial blood vessels which have important diagnostic purposes. Methods. Three Specimens (aSMA, Endomucin and control) of formalin-fixed paraffin embedded mouse embryo tissue sections have been de-waxed, rehydrated. Then they were covered with accurate primary antibody: αSMA slide in dilute mouse monoclonal anti-smooth muscle actin, Endomucin slide in dilute rat monoclonal anti-endomucin and the control slide gets just PBS (no-primary control). Then the sections were covered with the right secondary antibody: αSMA slide with biotinylated rabbit anti-mouse IgGIgG diluted and Endomucin slide with biotinylated rabbit anti-rat IgG, control slide with either antibody. Next color reagent was applied; it contains 3,3′-Diaminobenzidine and 0.3% hydrogen peroxide. Finally examine slides using a microscope. Results. The results showed that there was different brown 3,3′-Diaminobenzidine staining patterns in the two test slides for the individual primary antibodies. The 3,3′-Diaminobenzidine Staining was highly expressed in the external part of the section as a result of the presence of α-Smooth Muscle Actin. Whereas, in case of Endomucin, the stain is expressed in the central part of specimens due to presence of the endothelial tissue. and no staining in the primary control sections. Conclusion. As a result of the presence of α-Smooth Muscle Actin in the muscular tissue,3,3′-Diaminobenzidine Staining was highly expressed in the external part of the section. However, in case of Endomucin the stain is expressed in the central part of specimens due to presence of the endothelial tissue.
背景和目标。免疫组织化学(IHC)是通过特异性抗体检测组织切片中的抗原。与其他检测蛋白质的方法相比,它具有独特的优势,如α-平滑肌肌动蛋白和内啡肽,可以将抗原与其在组织中的位置联系起来。本研究的目的是鉴定心肌组织和动脉血管中的α-SMA和内啡肽,这两种蛋白具有重要的诊断意义。方法。对福尔马林固定石蜡包埋的小鼠胚胎组织切片进行脱蜡、复水处理,分别为aSMA、Endomucin和对照。然后涂上精确的一抗:稀释小鼠单克隆抗平滑肌肌动蛋白αSMA玻片,稀释大鼠单克隆抗内啡肽Endomucin玻片,对照玻片只涂PBS(无一抗)。然后涂上正确的二抗:αSMA玻片加生物素化兔抗小鼠IgGIgG稀释,Endomucin玻片加生物素化兔抗大鼠IgG稀释,对照玻片加任意一种抗体。下一道显色剂;它含有3,3 ' -二氨基联苯胺和0.3%的过氧化氢。最后用显微镜检查载玻片。结果。结果显示,两种载玻片中,单个一抗存在不同的棕色3,3 ' -二氨基苯胺染色模式。由于α-平滑肌肌动蛋白的存在,3,3′-二氨基苯胺染色在切片的外部高度表达。然而,在Endomucin的情况下,由于内皮组织的存在,染色在标本的中心部分表达。主对照切片未见染色。结论。由于肌肉组织中α-平滑肌肌动蛋白的存在,3,3 ' -二氨基苯丙胺染色在切片外侧高度表达。然而,在Endomucin的情况下,由于内皮组织的存在,染色在标本的中心部分表达。
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引用次数: 0
The Association Between Coronary Artery Disease and Type 2 Diabetes Mellitus in Libyan Adults: A Cross-Sectional Study 利比亚成人冠状动脉疾病与2型糖尿病的相关性:一项横断面研究
Pub Date : 2022-03-30 DOI: 10.47705/kjdmr.216111
Razk Abdalgwad, Ali Fadhlullah, Ahmed Balha
Background and objectives. Diabetes mellitus is a highly prevalent chronic multisystem disease and it has a significant impact on the health of many important organs in our body, including the cardiovascular system (CVS). This study aimed to determine the association between Type 2 diabetes mellites (T2DM) and the development of coronary artery disease (CAD). Methods. A retrospective cross-sectional study was conducted on patients who were diagnosed with CAD and T2DM. We examined the likelihood occurrence of CAD in T2DM patients using the Bayesian one sample test. Results. About 97 patients were confirmed to have CAD and were included in the study. The mean age of participants was 60±11.89. Approximately, 53 (54.6%) of patients were females, while 44 (45.4%) were males. The vast majority of patients had T2DM and CAD at 69 (71.1%) as opposed to only 28 (28.9%) of patients who did not have T2DM but had CAD. Moreover, there was a statistically significant increase in the likelihood of occurrence of CAD amongst the T2DM group. The percentage of patients who have T2DM with CAD was significantly higher than those who were not diagnosed with T2DM but had CAD at 69 (71.1%) compared to 28 (28.9%) (P = 0.002) for the group of T2DM concomitant with CAD, and the group of non-T2DM concomitant with CAD, respectively. Conclusion. There was a significant relationship between T2DM and CAD, suggesting the importance of intensive glycemic control in diabetic patients possibly via lifestyle modifications or medications in order to reduce or delay the possibility of occurrence of CAD amongst diabetic patients, in particular.
背景和目标。糖尿病是一种非常普遍的慢性多系统疾病,它对我们身体许多重要器官的健康有重大影响,包括心血管系统(CVS)。本研究旨在确定2型糖尿病(T2DM)与冠状动脉疾病(CAD)发展之间的关系。方法。对诊断为冠心病和2型糖尿病的患者进行回顾性横断面研究。我们使用贝叶斯单样本检验检验了2型糖尿病患者发生冠心病的可能性。结果。大约有97名患者被确诊为冠心病,并被纳入研究。参与者平均年龄为60±11.89岁。其中女性53例(54.6%),男性44例(45.4%)。绝大多数患有2型糖尿病和冠心病的患者为69例(71.1%),而没有2型糖尿病但患有冠心病的患者只有28例(28.9%)。此外,在T2DM组中,冠心病发生的可能性有统计学意义上的显著增加。T2DM合并CAD的患者比例显著高于未诊断为T2DM但有CAD的患者,分别为69例(71.1%),而T2DM合并CAD组和非T2DM合并CAD组分别为28例(28.9%)(P = 0.002)。结论。2型糖尿病和冠心病之间有显著的关系,这表明糖尿病患者加强血糖控制的重要性,可能通过改变生活方式或药物治疗,以减少或延迟糖尿病患者发生冠心病的可能性。
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引用次数: 0
Final Height Outcome in Girls with Turner Syndrome Treated with Growth Hormone and Low Dose Estrogen 生长激素和低剂量雌激素治疗特纳综合征女孩的最终身高结局
Pub Date : 2022-02-06 DOI: 10.47705/kjdmr.216109
We reported final height data of collected 28 cases with Turner Syndrome (TS) were confirmed with chromosomal analysis during height growth hormone therapy and late estrogen therapy. Participants were allocated into one of 3 Groups, Group A: 11 patients aged between 15-18 years-old, group B: 10 patients aged between 10 -15 years-old, group C: 7 patients younger than 10 years-old. In contrast to the duration of growth hormone & presentation, group B showed a significantly higher final height mean (147.5 ±6.5 cm) the best result well be obtained in group B treated with high doses of growth hormone for longer period. Records of female patients with TS confirmed by karyotype analysis were examined; 15 patients had the typical Turner karyotype and 13 patients had a karyotype indicative of one of the TS variations. Four of the sixteen individuals in variations lacked clinical stigmata associated with Turner Syndrome; the other nine had one or more of the usual clinical stigmata associated with TS. Two cases who had a complicated mosaic karyotype also possessed a Y chromosome. Three patients in group of classics had coarctation of the aorta and one patient in had variants of TS. 5 patients had primary hypothyroidism and received levothyroxine. two pts has hyperthyroidism. In Turner syndrome (TS), Growth Hormone (GH) treatment promotes growth and adult height. The benefit-risk ratio of supplementing GH with the weak androgen oxandrolone (Ox) is undefined. Growth hormone were administered (1.33 mg/kg/d) from the age of 8 years-old while estrogens were initiated at the age of 12 years-old. The increase in adult height (adult height minus predicted adult height) and safety factors were evaluated in a systematic manner.
我们报告了28例Turner综合征(TS)患者在身高生长激素治疗和晚期雌激素治疗期间的最终身高数据经染色体分析证实。参与者被分为3组,A组:11例15-18岁的患者,B组:10例10 -15岁的患者,C组:7例10岁以下的患者。与使用生长激素的时间和呈现时间相比,B组的最终身高平均值(147.5±6.5 cm)显著高于B组,且使用长时间高剂量生长激素的B组效果最好。对经核型分析证实的女性TS患者进行记录检查;15例患者具有典型的特纳核型,13例患者具有表明TS变异之一的核型。16个变异个体中有4个缺乏与特纳综合征相关的临床红斑;另外9例有一个或多个与TS相关的临床常见的柱头。2例具有复杂的马赛克核型的患者还具有Y染色体。经组主动脉缩窄3例,TS变异型1例,原发性甲状腺功能减退5例,行左旋甲状腺素治疗。两名PTS有甲状腺功能亢进。在特纳综合征(TS)中,生长激素(GH)治疗促进生长和成人身高。用弱雄激素奥雄龙(Ox)补充生长激素的利弊比尚未确定。8岁开始使用生长激素(1.33 mg/kg/d), 12岁开始使用雌激素。系统评价成人身高(成人身高减去预测成人身高)的增长和安全系数。
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引用次数: 0
Use of Traditional Recipes for Oral Care by Local People in Janzour City, Libya: A Qualitative Study 利比亚詹祖尔市当地人使用传统口腔护理方法的定性研究
Pub Date : 2022-02-03 DOI: 10.47705/kjdmr.216108
Background and objectives: Traditional medicine (TM) has gained attention from the public globally in recent times. However, a lack of studies is identified for individuals’ use of traditional medicine to treat dental issues. Libya’s traditional medicine is an example of traditions that include a number of plant- and non-plant-based approaches to dental and oral health. A qualitative descriptive study was used to explore the views on, use of, and access to TM in dentistry as an alternative to conventional dental care and oral pain relief among Libyans. A purposive sample of residents older than eighteen living in the city of Janzour was used, and sixteen semi-structured individual interviews were conducted virtually. The interviews aimed to gather data, including locally used names for plants used medicinally for oral health, ways of using the treatments, their effectiveness, adverse impacts, and how far each remedy was in popular use. Data analysis was conducted, and the results were fairly consistent and indicated relatively high levels of knowledge and usage of TM. Three main themes were extracted from the interviews:1) Different perspectives of the participants on TM. 2) Current practice and experience with TM. 3) Reasons for choosing TM. This study provides understandings for dentistry professionals of the kinds of traditional medicines which the public use for oral health. Building such understandings and awareness of the use of traditional medicines can help dental professionals to promote discussions of the practices which patients use, providing an opportunity for education in this area.
背景和目的:传统医学(TM)近年来受到全球公众的关注。然而,缺乏对个人使用传统药物治疗牙齿问题的研究。利比亚的传统医学就是一个例子,其中包括一些以植物和非植物为基础的牙齿和口腔保健方法。一项定性描述性研究被用来探讨意见,使用,并获得TM牙科作为替代传统牙科护理和口腔疼痛缓解在利比亚人。使用了居住在Janzour市的18岁以上居民的有目的样本,并进行了16次半结构化的个人访谈。访谈的目的是收集数据,包括当地用于口腔健康的药用植物的名称,使用这些治疗方法的方法,它们的有效性,不利影响,以及每种治疗方法的流行程度。对数据进行了分析,结果相当一致,显示了相对较高的TM知识和使用水平。从访谈中提取出三个主要主题:1)参与者对TM的不同观点。2)目前TM的实践和经验。3)选择TM的原因。本研究为牙科专业人员提供了对公众用于口腔健康的传统药物种类的了解。建立对传统药物使用的这种理解和认识可以帮助牙科专业人员促进对患者使用的做法的讨论,为这一领域的教育提供机会。
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引用次数: 0
Surface Chemical Analysis of Hydroxyapatite Compared to Glass Ionomer and Amalgam Materials Used as Retrograde Filling Material in Dentistry 牙科逆行充填材料羟基磷灰石与玻璃离子、银汞合金的表面化学分析
Pub Date : 2022-02-02 DOI: 10.47705/kjdmr.216107
The aim of this study was to analyses the surface chemistry of different materials used as retrograde filling and compare it with bulk chemical analyses reported. Surface analysis carried out using an X—ray Photoelectron Spectrometer (XPS) built by VG Scientific. Samples of HAP, GIC and Amalgam materials used were prepared as Discs of 10 mm diameter. These transferred on to XPS aluminum stubs. XPS spectra were obtained from the wide scan spectrum of amalgam, the following elements are present: tin (23.2%); mercury (6.6%); carbon (19%) and oxygen (51.2%). The wide scan spectrum of GIC the elements present in the surface of the material are: oxygen (41.1%); aluminum (5%); silicon (4.6%); carbon (36.1%); calcium (11.3%); fluorine (2.1%) and sodium (0.T). The XPS spectra were obtained from the wide scan spectrum of Hydroxyapatite the elements present in the surface are: Oxygen (49-4%), Carbon (33-9%), calcium (8-6%), and Phosphorus (8-4%). In conclusion, the chemical XPS analyses of the materials used as retrograde filling, have shown them to vary considerably with respect to bulk chemical composition. Further surface analysis could include narrow scans, manipulation of surface chemistry, coupled with in vitro and in vivo tests and experiments to determine the importance of different surface components on biocompatibility.
本研究的目的是分析不同材料的表面化学成分作为逆行填充,并比较其与散装化学分析报告。表面分析使用VG科学公司制造的x射线光电子光谱仪(XPS)进行。将HAP、GIC和Amalgam材料制成直径为10 mm的圆盘。这些转移到XPS铝存根上。对银汞合金的宽扫描谱图进行XPS分析,发现存在以下元素:锡(23.2%);汞(6.6%);碳(19%)和氧(51.2%)。GIC的宽扫描谱显示材料表面存在的元素有:氧(41.1%);铝(5%);硅(4.6%);碳(36.1%);钙(11.3%);氟(2.1%)和钠(0.T)。从羟基磷灰石的宽扫描光谱中获得XPS光谱,其表面存在的元素为:氧(49-4%)、碳(33-9%)、钙(8-6%)和磷(8-4%)。总之,化学XPS分析的材料用作逆行填充物,已经表明他们有相当大的变化相对于散装化学成分。进一步的表面分析可包括窄范围扫描、表面化学操作,以及体外和体内测试和实验,以确定不同表面成分对生物相容性的重要性。
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引用次数: 0
Effect of Nonsurgical Periodontal Therapy On IL-36 Levels in Serum, Gingival Crevicular Fluid of Type 2 Diabetic and Non-Diabetic Patients with Chronic Periodontitis 非手术牙周治疗对2型糖尿病和非糖尿病合并慢性牙周炎患者血清、龈沟液中IL-36水平的影响
Pub Date : 2022-01-11 DOI: 10.47705/kjdmr.216106
Objective: The aim of this study was to compare the level of inflammatory marker IL-36β in serum and gingival crevicular fluid in type 2 diabetic and non-diabetic patients with chronic periodontitis, before and after phase I therapy. Methods: A total of fifty subjects was included in this study; 20 Type 2 diabetic subjects with chronic periodontitis (group I) and 20 systemically healthy subjects with chronic periodontitis (group II) in addition to 10 systemically healthy subjects with clinically healthy gingiva as a control group (group III). The nonsurgical periodontal therapy was done to both group I and group II. Periodontal parameters, including plaque index, gingival index, bleeding on probing, probing depth and the clinical attachment level, in all the sites were recorded. GCF and serum were collected from all individuals included in the study; the first sample was collected from all groups (study and control) before phase I therapy. The second sample was collected 6 weeks after phase I therapy from group I& group II. Levels of IL-36β in GCF and serum were quantified using ELISA. Results. The current results showed statistically significant reduction in total level of IL-36β in serum and GCF in both groups; Type 2 diabetes with chronic periodontitis group (I) and systemically healthy with periodontitis group (II) after phase I therapy. Results also showed all clinical parameters were significantly improved after the phase I periodontal therapy in both groups I &II (p<0.001). Conclusions. Scaling and root planning (SRP) is the mainstay of treatment of periodontal diseases as SRP was effective in improving clinical parameters in diabetic and non-diabetic patients with chronic periodontitis. IL-36β could be used as a potential diagnostic marker for periodontal disease activity in both serum and gingival crevicular fluid.
目的:比较2型糖尿病和非糖尿病合并慢性牙周炎患者I期治疗前后血清和龈沟液中炎症标志物IL-36β的水平。方法:本研究共纳入50名受试者;20例2型糖尿病合并慢性牙周炎患者(I组)和20例全身健康的慢性牙周炎患者(II组),另外10例全身健康且临床牙龈健康的患者作为对照组(III组)。对I组和II组进行非手术牙周治疗。记录各部位的牙周参数,包括菌斑指数、牙龈指数、探诊时出血、探诊深度和临床附着程度。收集纳入研究的所有个体的GCF和血清;在I期治疗前从所有组(研究组和对照组)中收集第一个样本。第二份样本在I期治疗后6周从I组和II组中采集。ELISA法测定血清和GCF中IL-36β水平。结果。目前的结果显示,两组患者血清和GCF中IL-36β总水平均有统计学意义的降低;I期治疗后2型糖尿病伴慢性牙周炎组(I)和全身健康伴牙周炎组(II)。结果还显示,I组和ii组牙周治疗后所有临床参数均有显著改善(p<0.001)。结论。刮治和牙根规划(SRP)是治疗牙周病的主要方法,可以有效改善糖尿病和非糖尿病慢性牙周炎患者的临床参数。血清和龈沟液中IL-36β可作为牙周病活动性的潜在诊断标志物。
{"title":"Effect of Nonsurgical Periodontal Therapy On IL-36 Levels in Serum, Gingival Crevicular Fluid of Type 2 Diabetic and Non-Diabetic Patients with Chronic Periodontitis","authors":"","doi":"10.47705/kjdmr.216106","DOIUrl":"https://doi.org/10.47705/kjdmr.216106","url":null,"abstract":"Objective: The aim of this study was to compare the level of inflammatory marker IL-36β in serum and gingival crevicular fluid in type 2 diabetic and non-diabetic patients with chronic periodontitis, before and after phase I therapy. Methods: A total of fifty subjects was included in this study; 20 Type 2 diabetic subjects with chronic periodontitis (group I) and 20 systemically healthy subjects with chronic periodontitis (group II) in addition to 10 systemically healthy subjects with clinically healthy gingiva as a control group (group III). The nonsurgical periodontal therapy was done to both group I and group II. Periodontal parameters, including plaque index, gingival index, bleeding on probing, probing depth and the clinical attachment level, in all the sites were recorded. GCF and serum were collected from all individuals included in the study; the first sample was collected from all groups (study and control) before phase I therapy. The second sample was collected 6 weeks after phase I therapy from group I& group II. Levels of IL-36β in GCF and serum were quantified using ELISA. Results. The current results showed statistically significant reduction in total level of IL-36β in serum and GCF in both groups; Type 2 diabetes with chronic periodontitis group (I) and systemically healthy with periodontitis group (II) after phase I therapy. Results also showed all clinical parameters were significantly improved after the phase I periodontal therapy in both groups I &II (p<0.001). Conclusions. Scaling and root planning (SRP) is the mainstay of treatment of periodontal diseases as SRP was effective in improving clinical parameters in diabetic and non-diabetic patients with chronic periodontitis. IL-36β could be used as a potential diagnostic marker for periodontal disease activity in both serum and gingival crevicular fluid.","PeriodicalId":436335,"journal":{"name":"Khalij-Libya Journal of Dental and Medical Research","volume":"39 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123810191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Anatomical Causes of Infertility Diagnosed Using Imaging Tests in A Group of 100 Women 100名妇女影像学检查诊断不孕症的解剖原因
Pub Date : 2022-01-04 DOI: 10.47705/kjdmr.216105
Background and aims. The demographics of infertility differ dramatically from one region to another. Therefore, details about the causes and distribution of infertility of different localities and regions are essential for any effective management strategy. This study aimed to evaluate the distribution of the causes of infertility in a women population attending a tertiary healthcare facility. Methods. A cross-sectional observational study conducted in a gynecology clinic on female patients who came for infertility consultation or treatment between June -2019 and December-2020. The cause of infertility was diagnosed by the history, examination and investigation. Data were arranged in tables, and the frequency of each factor was calculated and therefore the prevalence was estimated using SPSS 25. Results. secondary infertility (53%) was more prevalent than primary infertility (47%). Pelvic inflammatory disease was the leading cause (40%) and it was associated with tubal factor infertility. Second cause was polycystic ovarian syndrome (PCOS) (33%). Infertility causes changed as the age of marriage increased. In females married for less than 5 years, PCOs was the main cause of infertility. Conclusion. Causes of infertility in women change according to the age group and the age of marriage. This study shows that PID is the most common cause of infertility in females followed by PCO. A significant association between infections and tubal factor infertility was found.
背景和目的。不同地区的不孕症人口统计差异很大。因此,详细了解不同地区和地区不孕症的病因和分布情况对于制定有效的管理策略至关重要。本研究旨在评估在三级医疗机构就诊的妇女人群中不孕症原因的分布。方法。在2019年6月至2020年12月期间,在妇科诊所对前来咨询或治疗不孕症的女性患者进行了横断面观察研究。通过病史、检查和调查诊断不孕症的原因。数据以表格形式排列,计算各因素出现的频率,用SPSS 25估计患病率。结果。继发性不孕症(53%)比原发性不孕症(47%)更为普遍。盆腔炎是主要原因(40%),它与输卵管性不孕有关。其次是多囊卵巢综合征(PCOS)(33%)。不孕的原因随着结婚年龄的增加而改变。在结婚少于5年的女性中,PCOs是不孕的主要原因。结论。妇女不孕的原因因年龄组和结婚年龄而异。本研究表明,PID是女性不孕最常见的原因,其次是PCO。发现感染与输卵管因素不孕之间存在显著关联。
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引用次数: 0
Tooth Loss and Prosthesis Replacement at El-Koms City El-Koms市的牙齿脱落和假体置换
Pub Date : 2021-12-31 DOI: 10.47705/kjdmr.216104
Background and objective.Lossof at least one tooth disturbs the structural balance of the remaining natural teeth and may result in widening of proximal contacts, and other deformities.The proportion of full and partial edentulous people, as well as their prosthetic therapy, were investigated El-Koms cityMethods.Patient demographics, the percentage of partial and completely edentulous patients, and their prosthetic treatment were collected at four dental clinics. Health services. Ministry of Health in El-Koms city. The study was approved by the prosthodontics department, Faculty of Dentistry, University of Al Marqab.In 2020, a total of 1000 people were assessed in four dental clinics, with 472 individuals being chosen as part of the sample study group. Patients were chosen based on their age, which ranged from 25 to 75 years old, and their dental records. ResultsThe majority of the study participants (n = 472) had missing teeth as follows: 27 patients are completely edentulous, 36 patients having a single edentulous arch, 348 patients being partially edentulous, and 61patients having no missing teeth.Edentulous jaws werecorrelated statistically significantly with age, being more common in older age (𝑝value 0.03).Males had a higher percentage of missing teeth than females, and as people got older, edentulous persons grew increasingly common. In both jaws, Class IIIpartial edentulous people were the most common. Conclusion.There is a high demand for prosthodontic treatment. The incidence of edentulous patients in Libya, as well as predisposing factors, are both unknown
背景和目的。失去至少一颗牙齿会扰乱其余天然牙齿的结构平衡,并可能导致近端接触变宽及其他畸形。调查El-Koms市全牙和部分无牙人群的比例,以及他们的义肢治疗情况。在四个牙科诊所收集患者人口统计数据,部分和完全无牙患者的百分比,以及他们的修复治疗。卫生服务。卫生部在El-Koms市。该研究得到了Al Marqab大学牙科学院口腔修复系的批准。2020年,四家牙科诊所共对1000人进行了评估,其中472人被选为样本研究组的一部分。患者的选择基于他们的年龄,从25岁到75岁,以及他们的牙科记录。结果472例缺牙患者中,全牙27例,单牙弓36例,部分缺牙348例,无缺牙61例。无牙颌与年龄有统计学上的显著相关,在老年人中更为常见(𝑝value 0.03)。男性缺牙的比例高于女性,随着年龄的增长,无牙的人变得越来越普遍。在双颌中,iii类部分无牙者最为常见。结论。人们对修复治疗的需求很大。在利比亚,无牙患者的发病率以及诱发因素都是未知的
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引用次数: 0
Ultra-High-Molecular-Weight-Polyethylene (UHMWPE) as Desired Polymer Material for Biomedical 超高分子量聚乙烯(UHMWPE)作为生物医学所需的高分子材料
Pub Date : 2021-12-05 DOI: 10.47705/kjdmr.216103
Assma Said
It is very important that any materials used as implant material work in harmony with the body. There will be drawback with every material. No matter how good, as nothing can be 100% identical as the natural human tissue. The body operates in an environment at a constant temperature of 37°C and pH of 7.25, so choice of materials will have to withstand these conditions. Incorrect use of material can cause rejection by the body, infection and even cancer, leading to more pain and discomfort by the patient. In turn the possibility of even further damage to the joint. The implant must work in the same way as the body part it is replacing- clear understanding of how the joint works is needed. Ultrahigh molecular weight polyethylene is considered as the standard material for Artificial joints to decrease the total weight and the wear rate to make it more flexible. This is what makes Ultra-High-Molecular-Weight-Polyethylene (UHMWPE) such an appropriate polymer. It is very widely used in total hip and knee joint replacements having the highest known impact strength of any thermoplastic presently made, can highly withstand abrasion, and has a very low coefficient of friction. Therefore, these properties, connected with extremely low moisture absorption, make UHMWPE especial material for the medical industry due to good industrial impact and wear resistance sliding applications. For moving joints, the friction would be damaging without the natural lubrication. In implant components this does not exist, however UHMWPE is self-lubricating, making it ideal for component such as an acetabular cup, which would wrap around a metallic femoral head in a hip joint. Also, UHMWPE has high impact strength, high toughness, and low elastic modulus, but it has disadvantages such as low tensile, transverse and compressive strengths with high creep rate. This review article deals with the history of UHMWPE, its material properties that make it an ideal candidate for total joints, implant-component fabrication procedures and provides insights as to why some of the implants eventually fail.
任何用作植入材料的材料都要与身体协调一致,这一点非常重要。每种材料都有缺点。不管有多好,因为没有什么能和天然人体组织完全一样。人体在恒温37°C和pH值7.25的环境中工作,因此材料的选择必须能够承受这些条件。不正确的使用材料会引起身体排斥,感染甚至癌症,导致患者更多的痛苦和不适。反过来,可能会进一步损害关节。植入物必须以与它所取代的身体部位相同的方式工作——需要清楚地了解关节是如何工作的。超高分子量聚乙烯被认为是人造关节的标准材料,以减少总重量和磨损率,使其更灵活。这就是超高分子量聚乙烯(UHMWPE)成为一种合适的聚合物的原因。它非常广泛地用于全髋关节和膝关节置换,具有目前已知的最高冲击强度的任何热塑性塑料,可以高度耐受磨损,并且具有非常低的摩擦系数。因此,这些性能,加上极低的吸湿性,使超高分子量聚乙烯成为医疗行业的特殊材料,因为它具有良好的工业冲击和耐磨滑动应用。移动关节,没有自然润滑摩擦会破坏。在植入部件中不存在这种情况,但超高分子量聚乙烯具有自润滑性,使其成为髋臼杯等部件的理想材料,髋臼杯可以包裹在髋关节的金属股骨头上。超高分子量聚乙烯具有高冲击强度、高韧性、低弹性模量等优点,但其抗拉强度、横向强度和抗压强度低,蠕变率高。本文综述了超高分子量聚乙烯(UHMWPE)的历史,其材料特性使其成为全关节的理想候选材料,植入物-组件制造程序,并提供了一些植入物最终失败的原因。
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引用次数: 1
Shaping Ability of Three Ni-Ti Rotary Systems in Curved Root Canals of Extracted Teeth 三种镍钛旋转系统在拔牙弯曲根管中的成形能力
Pub Date : 2021-11-27 DOI: 10.47705/kjdmr.216102
Showg Salem
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引用次数: 1
期刊
Khalij-Libya Journal of Dental and Medical Research
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