首页 > 最新文献

2022 IEEE 16th International Symposium on Medical Information and Communication Technology (ISMICT)最新文献

英文 中文
E-Textile Garment Simulation to Improve ECG Data Quality 电子纺织服装仿真提高心电数据质量
Caitlin G. Knowles, B. Sennik, Beomjun Ju, Marissa Noon, A. Mills, J. Jur
Achieving accurate fit and body contact pressure is one of the key issues in designing e-textiles such as electrocardiogram (ECG) sensing garments, in which ECG signal quality is dependent on the contact pressure of the electrodes on the skin. While this is a known mechanism, few strategies exist for predictive design as fabrics' body contact pressure response with strain is unique to the fabric's composition and structure. In this work, we propose a technique using 3D garment simulation to predict the body contact pressure of an ECG armband with screen printed Ag/AgCl electrodes. The contact pressure response with strain is evaluated for seven different polyester-spandex jersey knit fabrics. The effects of strain on the signal to noise ratio (SNR) and average R-peak height are measured for armbands of two different fabrics and five sizes. This technique shows potential to improve ECG data quality and shorten the prototyping process for compressive e-textile garments.
实现准确的贴合和人体接触压力是设计电子纺织品(如心电图传感服装)的关键问题之一,其中心电图信号质量取决于电极在皮肤上的接触压力。虽然这是一种已知的机制,但由于织物的身体接触压力对应变的响应是织物的组成和结构所特有的,因此很少有策略可以用于预测设计。在这项工作中,我们提出了一种使用3D服装模拟技术来预测带有丝网印刷Ag/AgCl电极的ECG臂带的身体接触压力。对7种不同的涤纶-氨纶针织物的接触压力响应进行了应变评价。测量了应变对两种不同面料和5种尺寸臂章的信噪比和平均r峰高度的影响。这项技术显示了提高ECG数据质量和缩短压缩电子纺织服装原型制作过程的潜力。
{"title":"E-Textile Garment Simulation to Improve ECG Data Quality","authors":"Caitlin G. Knowles, B. Sennik, Beomjun Ju, Marissa Noon, A. Mills, J. Jur","doi":"10.1109/ismict56646.2022.9828269","DOIUrl":"https://doi.org/10.1109/ismict56646.2022.9828269","url":null,"abstract":"Achieving accurate fit and body contact pressure is one of the key issues in designing e-textiles such as electrocardiogram (ECG) sensing garments, in which ECG signal quality is dependent on the contact pressure of the electrodes on the skin. While this is a known mechanism, few strategies exist for predictive design as fabrics' body contact pressure response with strain is unique to the fabric's composition and structure. In this work, we propose a technique using 3D garment simulation to predict the body contact pressure of an ECG armband with screen printed Ag/AgCl electrodes. The contact pressure response with strain is evaluated for seven different polyester-spandex jersey knit fabrics. The effects of strain on the signal to noise ratio (SNR) and average R-peak height are measured for armbands of two different fabrics and five sizes. This technique shows potential to improve ECG data quality and shorten the prototyping process for compressive e-textile garments.","PeriodicalId":436823,"journal":{"name":"2022 IEEE 16th International Symposium on Medical Information and Communication Technology (ISMICT)","volume":"48 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116815147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Wearable sensor system on chest for continuous measurement of blood pressure and other vital signs 胸部可穿戴传感器系统,用于连续测量血压和其他生命体征
A. Zienkiewicz, E. Vihriälä, Eveliina Seppälä, H. Ferdinando, T. Myllylä
Wearable health devices for continuous recording of heart rate (HR) and respiration are a common practice in wellness measurement applications. Typically, these can provide information such as health status and fitness level in daily life. At present, techniques that can provide all vital signals simultaneously, including blood pressure (BP), and validated for clinical accuracy, are lacking. One reason for this is that wearable sensors typically measure the signals from peripherals which are highly influenced by peripheral changes in blood circulation but also cause movement disturbances to recorder signals.In this paper, we present a wearable multimodal sensor system that allows continuous measurement of HR, respiration, and BP oscillations. All sensor elements are enclosed in a single, small-sized unit, which is placed on the chest above the sternum, ensuring monitoring of central BP oscillations. The device has been tested with voluntary subjects (adults and children) in various settings: in static positions, during sleep and in different physiological tasks. In addition, accuracy of the continuous BP measurement was tested against golden standard cuff based continuous BP monitor device, Finometer. We observed that the correlation of BP estimation with the reference had a Pearson’s coefficient in the range of 0.67 to 0.82 (mean 0.76). Both HR and breathing patterns were accurately followed as well. We present the technical solutions used in the sensors’ design, with an emphasis on the novel method to quantify BP from chest movements caused by cardiac activity. Furthermore, we discuss the advantages and challenges of the presented solution, and its feasibility for vital signals monitoring in both home and ambulatory environment.
连续记录心率(HR)和呼吸的可穿戴健康设备在健康测量应用中是一种常见的做法。通常,这些可以提供日常生活中的健康状况和健身水平等信息。目前,缺乏能够同时提供包括血压(BP)在内的所有生命信号并经临床准确性验证的技术。其中一个原因是,可穿戴传感器通常测量来自外围设备的信号,这些信号受到血液循环的外围变化的高度影响,但也会对记录信号造成运动干扰。在本文中,我们提出了一个可穿戴的多模态传感器系统,可以连续测量HR,呼吸和BP振荡。所有传感器元件都被封装在一个小单元中,放置在胸骨上方的胸部,确保监测中央血压振荡。该设备已经在不同的环境下对自愿受试者(成人和儿童)进行了测试:静态姿势、睡眠状态和不同的生理任务。此外,用基于金标准袖带的连续血压监测装置Finometer测试了连续血压测量的准确性。我们观察到BP估计值与参考值的相关性为0.67 ~ 0.82(平均0.76)。HR和呼吸模式也被准确地遵循。我们介绍了传感器设计中使用的技术解决方案,重点介绍了通过心脏活动引起的胸部运动来量化血压的新方法。此外,我们还讨论了该解决方案的优点和挑战,以及其在家庭和门诊环境中生命信号监测的可行性。
{"title":"Wearable sensor system on chest for continuous measurement of blood pressure and other vital signs","authors":"A. Zienkiewicz, E. Vihriälä, Eveliina Seppälä, H. Ferdinando, T. Myllylä","doi":"10.1109/ismict56646.2022.9828307","DOIUrl":"https://doi.org/10.1109/ismict56646.2022.9828307","url":null,"abstract":"Wearable health devices for continuous recording of heart rate (HR) and respiration are a common practice in wellness measurement applications. Typically, these can provide information such as health status and fitness level in daily life. At present, techniques that can provide all vital signals simultaneously, including blood pressure (BP), and validated for clinical accuracy, are lacking. One reason for this is that wearable sensors typically measure the signals from peripherals which are highly influenced by peripheral changes in blood circulation but also cause movement disturbances to recorder signals.In this paper, we present a wearable multimodal sensor system that allows continuous measurement of HR, respiration, and BP oscillations. All sensor elements are enclosed in a single, small-sized unit, which is placed on the chest above the sternum, ensuring monitoring of central BP oscillations. The device has been tested with voluntary subjects (adults and children) in various settings: in static positions, during sleep and in different physiological tasks. In addition, accuracy of the continuous BP measurement was tested against golden standard cuff based continuous BP monitor device, Finometer. We observed that the correlation of BP estimation with the reference had a Pearson’s coefficient in the range of 0.67 to 0.82 (mean 0.76). Both HR and breathing patterns were accurately followed as well. We present the technical solutions used in the sensors’ design, with an emphasis on the novel method to quantify BP from chest movements caused by cardiac activity. Furthermore, we discuss the advantages and challenges of the presented solution, and its feasibility for vital signals monitoring in both home and ambulatory environment.","PeriodicalId":436823,"journal":{"name":"2022 IEEE 16th International Symposium on Medical Information and Communication Technology (ISMICT)","volume":"85 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124993434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Development of a Synchronous Measurement System for WBAN Channel Modeling Considering Human Body Motion 考虑人体运动的WBAN信道建模同步测量系统的研制
Akira Saito, T. Aoyagi
Developments of WBAN channel models require a lot of experiments and simulations. To reduce them, our research group has been proposing a concept of WBAN channel modeling using human motions as parameters. In this report, a human motion and received signal strength synchronization measurement system is proposed. Human motion data is collected by a motion capture device (MOCAP) and the received signal strength (RSSI) data is collected by a BLE wireless device. To synchronize MOCAP and BLE data, a gesture-based method is proposed and confirmed by experiments. We also verified the operation of the measurement system and the possibility of path-loss or channel modeling based on human motion parameters. By using the measured human motion and RSSI data, RSSIs of future times are predicted by machine learning methods, RNN (Recurrent neural network), and LSTM (Long short-term memory). In conclusion, it was found that the RSSI in the future can be predicted to some extent from the past values of human body movements. This result would suggest the possibility of the modeling of WBAN channel variation with human motion as parameters.
WBAN信道模型的开发需要大量的实验和仿真。为了减少它们,我们的研究小组提出了一种使用人体运动作为参数的WBAN信道建模概念。本文提出了一种人体运动与接收信号强度同步测量系统。人体运动数据由动作捕捉设备(MOCAP)采集,接收信号强度(RSSI)数据由BLE无线设备采集。为了实现MOCAP和BLE数据的同步,提出了一种基于手势的方法,并通过实验进行了验证。我们还验证了测量系统的运行以及基于人体运动参数的路径损失或通道建模的可能性。通过测量人体运动和RSSI数据,通过机器学习方法、RNN(循环神经网络)和LSTM(长短期记忆)预测未来时间的RSSI。综上所述,我们发现从过去的人体运动值可以在一定程度上预测未来的RSSI。这一结果为以人体运动为参数建立WBAN信道变化模型提供了可能性。
{"title":"Development of a Synchronous Measurement System for WBAN Channel Modeling Considering Human Body Motion","authors":"Akira Saito, T. Aoyagi","doi":"10.1109/ismict56646.2022.9828197","DOIUrl":"https://doi.org/10.1109/ismict56646.2022.9828197","url":null,"abstract":"Developments of WBAN channel models require a lot of experiments and simulations. To reduce them, our research group has been proposing a concept of WBAN channel modeling using human motions as parameters. In this report, a human motion and received signal strength synchronization measurement system is proposed. Human motion data is collected by a motion capture device (MOCAP) and the received signal strength (RSSI) data is collected by a BLE wireless device. To synchronize MOCAP and BLE data, a gesture-based method is proposed and confirmed by experiments. We also verified the operation of the measurement system and the possibility of path-loss or channel modeling based on human motion parameters. By using the measured human motion and RSSI data, RSSIs of future times are predicted by machine learning methods, RNN (Recurrent neural network), and LSTM (Long short-term memory). In conclusion, it was found that the RSSI in the future can be predicted to some extent from the past values of human body movements. This result would suggest the possibility of the modeling of WBAN channel variation with human motion as parameters.","PeriodicalId":436823,"journal":{"name":"2022 IEEE 16th International Symposium on Medical Information and Communication Technology (ISMICT)","volume":"44 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129193301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multi-classification for EEG Motor Imagery Signals using Auto-selected Filter Bank Regularized Common Spatial Pattern 基于自选择滤波器组正则化公共空间模式的脑电运动图像信号多分类
Yang An, Sang Hun Han, S. Ling
Motor Imagery (MI) is a critical topic in Brain-Computer Interface (BCI). Due to the low signal-to-noise ratio, it is not easy to accurately classify motor imagery signals, especially for multiple classification tasks. Common Spatial Pattern (CSP) is a spatial transformation method that can effectively extract spatial features of EEG signals. However, the covariance matrix is inaccurate due to the small training data size,. Thus, in this paper, a regularization parameter auto-selection algorithm is proposed to automatically adjust the ratio of the covariance matrix calculated by other subjects’ data based on the mutual information. It can be used to tackle the problem of an inaccurate mixed covariance matrix caused by fixed regularization parameters.To illustrate the merits of the proposed Auto-selected Filter Bank Regularized Common Spatial Pattern (AFBRCSP), we used the ten folds cross-validation accuracy and Kappa as the evaluation metrics to evaluate two data sets (BCI4-2a and BCI3a data set). Both data set include four mental classes. By using BCI4-2a data set, we found that the mean accuracy of AFBRSP is 77.31% and the Kappa is 0.6975, which is higher than Filter Bank Regularized Common Spatial Pattern (FBRCSP) by 5.67% and 0.0756, respectively. By using BCI3a data set, the proposed AFBRCSP improved the accuracy by 8.34% and the Kappa by 0.1111 compared with FBRCSP where the mean accuracy of AFBRCSP is 80.56%, and the kappa is 0.7407. The overall Kappa obtained by the proposed method is also higher than some state-of-the-art methods, implying that the proposed method is more reliable.
运动意象(MI)是脑机接口(BCI)研究的一个重要课题。由于运动图像信号的信噪比较低,很难对运动图像信号进行准确的分类,特别是对于多个分类任务。共同空间模式(CSP)是一种能够有效提取脑电信号空间特征的空间变换方法。但由于训练数据量小,协方差矩阵不准确。因此,本文提出了一种正则化参数自动选择算法,根据互信息自动调整其他受试者数据计算的协方差矩阵的比例。它可以用来解决固定正则化参数导致的混合协方差矩阵不准确的问题。为了说明所提出的自动选择滤波器组正则化公共空间模式(AFBRCSP)的优点,我们使用十倍交叉验证精度和Kappa作为评估指标来评估两个数据集(BCI4-2a和BCI3a数据集)。这两个数据集都包括四个心理类别。利用BCI4-2a数据集,我们发现AFBRSP的平均准确率为77.31%,Kappa为0.6975,分别比滤波组正则化公共空间模式(Filter Bank regularization Common Spatial Pattern, FBRCSP)高5.67%和0.0756。使用BCI3a数据集,与FBRCSP相比,AFBRCSP的准确率提高了8.34%,Kappa提高了0.1111,其中AFBRCSP的平均准确率为80.56%,Kappa为0.7407。所提方法得到的总体Kappa值也高于一些现有方法,表明所提方法的可靠性更高。
{"title":"Multi-classification for EEG Motor Imagery Signals using Auto-selected Filter Bank Regularized Common Spatial Pattern","authors":"Yang An, Sang Hun Han, S. Ling","doi":"10.1109/ismict56646.2022.9828164","DOIUrl":"https://doi.org/10.1109/ismict56646.2022.9828164","url":null,"abstract":"Motor Imagery (MI) is a critical topic in Brain-Computer Interface (BCI). Due to the low signal-to-noise ratio, it is not easy to accurately classify motor imagery signals, especially for multiple classification tasks. Common Spatial Pattern (CSP) is a spatial transformation method that can effectively extract spatial features of EEG signals. However, the covariance matrix is inaccurate due to the small training data size,. Thus, in this paper, a regularization parameter auto-selection algorithm is proposed to automatically adjust the ratio of the covariance matrix calculated by other subjects’ data based on the mutual information. It can be used to tackle the problem of an inaccurate mixed covariance matrix caused by fixed regularization parameters.To illustrate the merits of the proposed Auto-selected Filter Bank Regularized Common Spatial Pattern (AFBRCSP), we used the ten folds cross-validation accuracy and Kappa as the evaluation metrics to evaluate two data sets (BCI4-2a and BCI3a data set). Both data set include four mental classes. By using BCI4-2a data set, we found that the mean accuracy of AFBRSP is 77.31% and the Kappa is 0.6975, which is higher than Filter Bank Regularized Common Spatial Pattern (FBRCSP) by 5.67% and 0.0756, respectively. By using BCI3a data set, the proposed AFBRCSP improved the accuracy by 8.34% and the Kappa by 0.1111 compared with FBRCSP where the mean accuracy of AFBRCSP is 80.56%, and the kappa is 0.7407. The overall Kappa obtained by the proposed method is also higher than some state-of-the-art methods, implying that the proposed method is more reliable.","PeriodicalId":436823,"journal":{"name":"2022 IEEE 16th International Symposium on Medical Information and Communication Technology (ISMICT)","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131881497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Real-Time Elderly Monitoring for Senior Safety by Lightweight Human Action Recognition 基于轻量级人体动作识别的老年人安全实时监控
Han Sun, Yu Chen
With an increasing number of elders living alone, care-giving from a distance becomes a compelling need, particularly for safety. Real-time monitoring and action recognition are essential to raise an alert timely when abnormal behaviors or unusual activities occur. While wearable sensors are widely recognized as a promising solution, highly depending on user’s ability and willingness makes them inefficient. In contrast, video streams collected through non-contact optical cameras provide richer information and release the burden on elders. In this paper, leveraging the Independently-Recurrent neural Network (IndRNN) we propose a novel Real-time Elderly Monitoring for senior Safety (REMS) based on lightweight human action recognition (HAR) technology. Using captured skeleton images, the REMS scheme is able to recognize abnormal behaviors or actions and preserve the user’s privacy. To achieve a high accuracy, the HAR module is trained and fine-tuned using multiple databases. An extensive experimental study verified that REMS system preforms action recognition accurately and timely. REMS meets the design goals as a privacy-preserving elderly safety monitoring system and possesses the potential to be adopted in various smart monitoring systems.
随着越来越多的老年人独居,远距离照顾成为一种迫切的需求,尤其是出于安全考虑。实时监控和动作识别是在发生异常行为或异常活动时及时发出警报的关键。虽然可穿戴传感器被广泛认为是一种很有前途的解决方案,但高度依赖于用户的能力和意愿使其效率低下。相比之下,通过非接触式光学相机收集的视频流提供了更丰富的信息,减轻了老年人的负担。本文利用独立循环神经网络(IndRNN)提出了一种基于轻量级人体动作识别(HAR)技术的老年人安全实时监测(REMS)。利用捕获的骨架图像,REMS方案能够识别异常行为或动作并保护用户的隐私。为了达到高精度,HAR模块使用多个数据库进行训练和微调。大量的实验研究验证了REMS系统能够准确、及时地进行动作识别。REMS达到了保护隐私的老年人安全监控系统的设计目标,具有在各种智能监控系统中采用的潜力。
{"title":"Real-Time Elderly Monitoring for Senior Safety by Lightweight Human Action Recognition","authors":"Han Sun, Yu Chen","doi":"10.1109/ismict56646.2022.9828343","DOIUrl":"https://doi.org/10.1109/ismict56646.2022.9828343","url":null,"abstract":"With an increasing number of elders living alone, care-giving from a distance becomes a compelling need, particularly for safety. Real-time monitoring and action recognition are essential to raise an alert timely when abnormal behaviors or unusual activities occur. While wearable sensors are widely recognized as a promising solution, highly depending on user’s ability and willingness makes them inefficient. In contrast, video streams collected through non-contact optical cameras provide richer information and release the burden on elders. In this paper, leveraging the Independently-Recurrent neural Network (IndRNN) we propose a novel Real-time Elderly Monitoring for senior Safety (REMS) based on lightweight human action recognition (HAR) technology. Using captured skeleton images, the REMS scheme is able to recognize abnormal behaviors or actions and preserve the user’s privacy. To achieve a high accuracy, the HAR module is trained and fine-tuned using multiple databases. An extensive experimental study verified that REMS system preforms action recognition accurately and timely. REMS meets the design goals as a privacy-preserving elderly safety monitoring system and possesses the potential to be adopted in various smart monitoring systems.","PeriodicalId":436823,"journal":{"name":"2022 IEEE 16th International Symposium on Medical Information and Communication Technology (ISMICT)","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124559225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Optically Active Bionanomachine Interfaces Build Therapeutic Nanonetworks for Glioblastoma Multiforme 光学活性生物机器界面构建多形性胶质母细胞瘤治疗性纳米网络
Avraam El Hamidieh, Nikolaos Dietis, A. Samoylenko, I. Meiser, Niovi Nicolaou, Eslam Abdelrady, A. Zhyvolozhnyi, S. Vainio, A. Odysseos
The evolution of Glioblastoma Multiforme (GBM) is defined by the dynamics of growing bionanomachine networks in an interplay between "senders" or "transceivers" and "receivers". Central to this process are the inter-communications between sub-cellular bionanomachines secreted by GBM cells in the form of exosomes. Herein we present a dynamic cell-based therapeutic nanonetwork of genetically engineered optically active bionanomachines. The communication paradigm is defined by the interaction between neural stem cell-derived exosomes expressing Enhanced Green Fluorescent Protein and GBM cells expressing Tandem Dimer Tomato protein (tdT), based on the dynamic transfer of energies of excited state bionanomachines in resonance. With EGFP serving as energy donor and tdT as energy acceptor we provide multilevel evidence validating a Förster Resonance Energy Transfer - mediated interaction between GBM cells and exosomes, therefore documenting their sustainable and close proximity. Such an approach has the potential to enable wireless communication between optically active bionanomachines via quantifiable interfaces within channel networks, further enabling mechanistic and therapeutic models.
多形性胶质母细胞瘤(GBM)的进化是由在“发送者”或“收发者”和“接收者”之间相互作用的不断增长的生物神经网络的动力学所定义的。这一过程的核心是由GBM细胞以外泌体的形式分泌的亚细胞生物异常机器之间的相互通信。在这里,我们提出了一个动态的基于细胞的治疗纳米网络的基因工程光学活性生物机器。这种通讯模式是由表达增强型绿色荧光蛋白的神经干细胞衍生外泌体和表达串联二聚体番茄蛋白(tdT)的GBM细胞之间的相互作用所定义的,这种相互作用基于激发态生物异常机器在共振中的能量动态转移。EGFP作为能量供体,tdT作为能量受体,我们提供了多层次的证据,验证了Förster共振能量转移介导的GBM细胞和外泌体之间的相互作用,因此记录了它们的持续和密切的关系。这种方法有可能通过通道网络中的可量化接口实现光活性生物机器之间的无线通信,进一步实现机制和治疗模型。
{"title":"Optically Active Bionanomachine Interfaces Build Therapeutic Nanonetworks for Glioblastoma Multiforme","authors":"Avraam El Hamidieh, Nikolaos Dietis, A. Samoylenko, I. Meiser, Niovi Nicolaou, Eslam Abdelrady, A. Zhyvolozhnyi, S. Vainio, A. Odysseos","doi":"10.1109/ismict56646.2022.9828125","DOIUrl":"https://doi.org/10.1109/ismict56646.2022.9828125","url":null,"abstract":"The evolution of Glioblastoma Multiforme (GBM) is defined by the dynamics of growing bionanomachine networks in an interplay between \"senders\" or \"transceivers\" and \"receivers\". Central to this process are the inter-communications between sub-cellular bionanomachines secreted by GBM cells in the form of exosomes. Herein we present a dynamic cell-based therapeutic nanonetwork of genetically engineered optically active bionanomachines. The communication paradigm is defined by the interaction between neural stem cell-derived exosomes expressing Enhanced Green Fluorescent Protein and GBM cells expressing Tandem Dimer Tomato protein (tdT), based on the dynamic transfer of energies of excited state bionanomachines in resonance. With EGFP serving as energy donor and tdT as energy acceptor we provide multilevel evidence validating a Förster Resonance Energy Transfer - mediated interaction between GBM cells and exosomes, therefore documenting their sustainable and close proximity. Such an approach has the potential to enable wireless communication between optically active bionanomachines via quantifiable interfaces within channel networks, further enabling mechanistic and therapeutic models.","PeriodicalId":436823,"journal":{"name":"2022 IEEE 16th International Symposium on Medical Information and Communication Technology (ISMICT)","volume":"40 2","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114035046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Remote Secure eHealth Provision: ETSI SmartBAN as an Enabler 远程安全电子健康提供:ETSI SmartBAN作为推动者
M. Hämäläinen, L. Mucchi, Tuomas Paso
Utilisation of Internet of Things (IoT) is spreading fast in modern home and industrial automation, but IoT solutions can also be widely utilised in healthcare domain. Monitoring of a person's vital signs and the connectivity between different medical devices are moving towards wireless implementation. Wearables and other health and wellbeing related personal gadgets carried by humans, or even implanted inside a human, are seeing to be more popular in healthcare applications. To respond to these challenges, new technologies in different domains are continuously developed. This paper is discussing the possibilities to effectively and reliably deliver eHealth services outside hospitals or other care units. In addition, we will introduce how ETSI SmartBAN can be utilised in various eHealth applications as well as how the security aspects should be taken into account when dealing with personal data.
物联网(IoT)在现代家庭和工业自动化中的应用正在迅速普及,但物联网解决方案也可以广泛应用于医疗保健领域。对人的生命体征的监测和不同医疗设备之间的连接正朝着无线实现的方向发展。可穿戴设备和其他与健康和福祉相关的个人设备,由人类携带,甚至植入人体,在医疗保健应用中越来越受欢迎。为了应对这些挑战,不同领域的新技术不断发展。本文讨论了在医院或其他护理单位之外有效可靠地提供电子医疗服务的可能性。此外,我们亦会介绍ETSI SmartBAN如何应用于不同的电子健康应用,以及在处理个人资料时应如何考虑安全问题。
{"title":"Remote Secure eHealth Provision: ETSI SmartBAN as an Enabler","authors":"M. Hämäläinen, L. Mucchi, Tuomas Paso","doi":"10.1109/ismict56646.2022.9828264","DOIUrl":"https://doi.org/10.1109/ismict56646.2022.9828264","url":null,"abstract":"Utilisation of Internet of Things (IoT) is spreading fast in modern home and industrial automation, but IoT solutions can also be widely utilised in healthcare domain. Monitoring of a person's vital signs and the connectivity between different medical devices are moving towards wireless implementation. Wearables and other health and wellbeing related personal gadgets carried by humans, or even implanted inside a human, are seeing to be more popular in healthcare applications. To respond to these challenges, new technologies in different domains are continuously developed. This paper is discussing the possibilities to effectively and reliably deliver eHealth services outside hospitals or other care units. In addition, we will introduce how ETSI SmartBAN can be utilised in various eHealth applications as well as how the security aspects should be taken into account when dealing with personal data.","PeriodicalId":436823,"journal":{"name":"2022 IEEE 16th International Symposium on Medical Information and Communication Technology (ISMICT)","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133786664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
PROASSIST4.0: An Optimized Tele-Assistance System for the Future Healthcare PROASSIST4.0:面向未来医疗保健的优化远程辅助系统
L. Mucchi, S. Jayousi, P. Cappanera, Filippo Visintin, P. Zoppi, E. Paoletti, Simona Geli, Pietro Dionisio, E. Tamburini, C. Paggetti
An efficient management of chronic patients is a key element in the current and future Healthcare context.This paper aims at providing an overview of the PROASSIST 4.0 solution for an healthcare assistance territorial model 4.0. The proposed service relies on the integration between the organizational assets and advanced ICT technologies: a dynamic and adaptive system able to respond to the needs of citizens / patients and to support staff healthcare in the management of an ever-increasing number of patients is proposed. This is achieved by optimizing the scheduling of the territorial assistance based on multiple occurrences and actual patients’ health status.
在当前和未来的医疗保健环境中,对慢性患者的有效管理是一个关键因素。本文旨在概述用于医疗保健援助区域模型4.0的PROASSIST 4.0解决方案。拟议的服务依赖于组织资产和先进的信息通信技术之间的整合:提出了一个动态和适应性系统,能够响应公民/患者的需求,并在管理越来越多的患者时支持工作人员的医疗保健。这是通过基于多次发生和实际患者健康状况优化区域援助的调度来实现的。
{"title":"PROASSIST4.0: An Optimized Tele-Assistance System for the Future Healthcare","authors":"L. Mucchi, S. Jayousi, P. Cappanera, Filippo Visintin, P. Zoppi, E. Paoletti, Simona Geli, Pietro Dionisio, E. Tamburini, C. Paggetti","doi":"10.1109/ismict56646.2022.9828045","DOIUrl":"https://doi.org/10.1109/ismict56646.2022.9828045","url":null,"abstract":"An efficient management of chronic patients is a key element in the current and future Healthcare context.This paper aims at providing an overview of the PROASSIST 4.0 solution for an healthcare assistance territorial model 4.0. The proposed service relies on the integration between the organizational assets and advanced ICT technologies: a dynamic and adaptive system able to respond to the needs of citizens / patients and to support staff healthcare in the management of an ever-increasing number of patients is proposed. This is achieved by optimizing the scheduling of the territorial assistance based on multiple occurrences and actual patients’ health status.","PeriodicalId":436823,"journal":{"name":"2022 IEEE 16th International Symposium on Medical Information and Communication Technology (ISMICT)","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117119012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
2022 IEEE 16th International Symposium on Medical Information and Communication Technology (ISMICT)
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1