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Management of Fournier’s Gangrene; A Randomized Controlled Trial at High Volume Center Comparing the efficacy of Honey and Eusol Dressing in Wound Healing 富尼耶坏疽的治疗大容量中心随机对照试验比较蜂蜜和乌苏尔敷料在伤口愈合中的疗效
IF 0.1 Q4 Medicine Pub Date : 2019-04-10 DOI: 10.22442/jlumhs.191810593
S. Ahmed, Imran Memon, Zakir Hussain Rajpar, M. Asim, A. Anwar, W. Elahi
OBJECTIVE: To assess the effectiveness of honey dressing in Fournier’s Gangrene against conventional Edinburgh University solution of lime (EUSOL) dressing.METHODOLOGY: This was a prospective experimental study conducted in Liaquat National Medical College and Hospital Karachi for duration of 5 and half years. Total 44 patients having gangrene and no co morbid conditions were included in this study. Patients who had co-morbid conditions like derangedcoagulation profile and CVA, who were not willing to participate or loss to follow up were excluded from the study. After getting baseline blood workup (i.e. CBC, S. Creatinine, S. Electrolytes, Urine D/R, C/S and Diabetic workup) done and taking consent, the patients were immediately shifted to operation theatre, the incision and drainage was performed, and the necrotic tissues were debrided. Pus cultures were sent, and patients were started on routine intravenous antibiotics (3rd generation Cephalosporin and metronidazole). A Dressing of wound was done randomly by honey in Group A and by Eusol inGroup B. Patients were discharged after wound was completely healed. The data were obtained and analyzed by using SPSS version 20. Mann-Whitney U-test and chi-square test was applied to find out the significance.RESUTS: The patients in Group A got slough cleared in4.82±0.96 days, on average requiring 3.22±0.75 number of debridement’s, complete wound healing and duration of hospital stay being 9.54±0.74 days. The patients in Group B got slough cleared in 8±0.87 days, requiring 5.32±0.72 number of debridement’s,complete wound healing and duration of hospital stay 13.68±1.09 days.There was a significant difference in slough clearance, number of debridement’s required, time taken for complete wound healing and hospital stay between Group A and Group B (P-value <0.001).CONCLUSION: This study predicted that honey is very valuable in the management of Fournier’s gangrene as it ensured early clearance of slough, required lesser number of debridement’s, had early wound healing and had relatively shorter duration of stay in hospital than those treated with conventional EUSOL as dressing material.
目的:评价蜂蜜敷料治疗富尼耶坏疽与传统爱丁堡大学石灰溶液(EUSOL)敷料的疗效。方法:这是一项在利亚奎特国立医学院和卡拉奇医院进行的为期5年半的前瞻性实验研究。本研究共纳入44例无合并症的坏疽患者。有凝血功能紊乱和CVA等合并症的患者不愿意参与或失去随访的患者被排除在研究之外。在完成基线血液检查(即CBC、S.肌酐、S.电解质、尿D/R、C/S和糖尿病检查)并取得同意后,立即转至手术室,进行切口引流,并清除坏死组织。送脓培养,患者开始常规静脉注射抗生素(第3代头孢菌素和甲硝唑)。A组随机用蜂蜜包扎创面,b组随机用Eusol包扎创面,创面完全愈合后出院。采用SPSS 20对数据进行统计分析。采用Mann-Whitney u检验和卡方检验进行显著性检验。结果:A组患者清痂时间为4.82±0.96 d,平均清创次数为3.22±0.75次,伤口完全愈合,住院时间为9.54±0.74 d。B组患者清痂时间为8±0.87 d,清创次数为5.32±0.72次,创面完全愈合,住院时间为13.68±1.09 d。a组和B组在结痂清除率、所需清创次数、伤口完全愈合时间和住院时间方面差异有统计学意义(p值<0.001)。结论:本研究预测蜂蜜在富尼耶坏疽的治疗中具有较好的应用价值,与传统的EUSOL作为敷料治疗相比,蜂蜜能较早清除痂皮,清创次数少,伤口愈合早,住院时间短。
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引用次数: 0
Transurethral Resection in benign Prostatic Hyperplasia; An Observational Study Highlighting the Correlation of the Resected Tissue with Electrolytes and Hemoglobin 经尿道前列腺切除术治疗良性前列腺增生一项观察性研究强调了切除组织与电解质和血红蛋白的相关性
IF 0.1 Q4 Medicine Pub Date : 2019-03-30 DOI: 10.22442/jlumhs.191810594
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引用次数: 0
Bacterial Sensitivity Pattern іn Nеоnаtаl Ѕерѕіѕ at Civil Hospital Hyderabad 在海得拉巴民用医院的细菌敏感性模式<e:1> nintel nintel intel Ѕерѕіѕ
IF 0.1 Q4 Medicine Pub Date : 2019-03-30 DOI: 10.22442/jlumhs.191810596
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引用次数: 0
Outcome of Tuberculous Meningitis in Adults 成人结核性脑膜炎的预后
IF 0.1 Q4 Medicine Pub Date : 2019-03-30 DOI: 10.22442/jlumhs.191810597
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引用次数: 3
A Meta Analysis on the Ethnic Differences in Bone Mineral Density on DEXA Scan in Pakistan 巴基斯坦DEXA扫描骨密度种族差异的Meta分析
IF 0.1 Q4 Medicine Pub Date : 2019-03-30 DOI: 10.22442/jlumhs.191810592
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引用次数: 0
Level of Actual Physical Fitness and its Perception among Students of Physiotherapy in Lahore 拉合尔地区物理治疗学生实际体质水平及其感知
IF 0.1 Q4 Medicine Pub Date : 2019-03-30 DOI: 10.22442/jlumhs.191810602
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引用次数: 3
Role of Paraoxonase-1 (Q192R) Gene Polymorphism in Coronary Artery Disease in Saudi Arabian Population 对氧磷酶1 (Q192R)基因多态性在沙特阿拉伯人群冠状动脉疾病中的作用
IF 0.1 Q4 Medicine Pub Date : 2019-03-30 DOI: 10.22442/jlumhs.191810598
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引用次数: 1
Ponseti Technique in Neglected Club Foot Children with Age between 3 and 11 Years 3 - 11岁被忽视的内翻足儿童的Ponseti技术
IF 0.1 Q4 Medicine Pub Date : 2019-03-30 DOI: 10.22442/jlumhs.191810595
Muhammad Jamil, A. A. Siddiqui, K. M. Khan, J. Kumar, M. Katto, Malik Ahmed, M. Pirwani
OBJECTIVE: To evaluate the Ponseti treatment in neglected club foot patients. Result of this study shallhelp us to manage untreated or neglected patients with club foot in better way and this study shallprovide platform for bigger studies on clubfoot in Pakistan.METHODOLOGY: This multicentre observational cross sectional study was conducted on retrospectivedata of patients registered to Ponseti Club foot Clinic between July 2013 to Dec 2016 at Dr Ruth PfauCivil Hospital Karachi and Jinnah postgraduate Medical Center, Karachi. In this study 41 feet in 28 patientswith Neglected club foot between 3 to 11 years were treated by Ponseti guidelines for older child(already walking child). Deformity was assessed with pirani scoring. Average follow up time was 3 years.RESULTS: Painless plantigrate foot was obtained in all patients. In 3 patients equinus deformityrecurred. Two were managed with recasting while in the third one along with recasting and retenotomywas undertaken. In 2 patients mild varus was recurred, which was managed with recasting. One patientwas lost to follow-up after 2 years.CONCLUSION: This study conclude that treatment of neglected idiopathic club foot patients presentingto us after walking age with Ponseti method according to Ponseti guidelines for older children is safe,effective and low cost method. It also reduces the risk of excessive surgical procedures.
目的:评价被忽视的内翻足患者Ponseti的治疗效果。本研究的结果将有助于我们更好地管理未治疗或被忽视的内翻足患者,并为巴基斯坦内翻足的更大规模研究提供平台。方法:这项多中心观察性横断面研究对2013年7月至2016年12月在卡拉奇Ruth PfauCivil医院和卡拉奇真纳研究生医学中心的Ponseti内翻足诊所登记的患者进行了回顾性研究。在这项研究中,28名3至11岁的被忽视的畸形足患者中有41人接受了Ponseti指南的治疗,该指南适用于年龄较大的儿童(已经会走路的儿童)。用皮拉尼评分法评估畸形。平均随访时间为3年。结果:所有患者均获得无痛植足。3例患者马蹄畸形复发。其中2例行重铸术,3例行重铸术并保留切开术。2例轻度内翻复发,经重铸处理。1例患者2年后失访。结论:本研究认为,根据Ponseti大龄儿童指南,采用Ponseti方法治疗行走年龄后被忽视的特发性内翻足患者是一种安全、有效、低成本的方法。它还减少了过度手术的风险。
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引用次数: 2
Frequency of Procedural Errors during Root Canal Treatment Performed by House Officers in Private Teaching Dental Hospital 私立教学牙科医院住院医师进行根管治疗过程中程序错误的频率
IF 0.1 Q4 Medicine Pub Date : 2019-03-30 DOI: 10.22442/jlumhs.191810601
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引用次数: 2
Comparative Study of Oral versus Intravenous Iron Therapy in Patients of Chronic Renal Failure Receiving Recombinant Human Erythropoietin 口服与静脉铁治疗慢性肾衰竭患者接受重组人促红细胞生成素的比较研究
IF 0.1 Q4 Medicine Pub Date : 2019-03-30 DOI: 10.22442/jlumhs.191810599
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引用次数: 1
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Journal of the Liaquat University of Medical and Health Sciences
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