Pub Date : 2022-09-13DOI: 10.1080/21695717.2022.2122331
J. Costa, M. Coutinho, T. Soares, Luís Meireles
Abstract Introduction Oculo-auriculo-vertebral spectrum (OAVS) is aetiologically/pathogenetically a heterogeneous disorder. This study focuses on investigating of maternal drug intake during pregnancy in OAVS cases. Materials and methods Our sample was composed of 114 paediatric cases of OAVS. For each patient, an evaluation form seeking identity, medical history, pregnancy and family data, physical/dysmorphological findings and results from complementary tests was applied. Through the analysis of all the forms applied, the history of drug exposure/maternal diseases were retrospectively studied. Results The age of the population studied ranged between 1 month and 18 years, the majority being male. Regarding otological features, most had pinna involvement: microtia (86.6%); preauricular appendices (41.6%) and preauricular sinus (15.7%). External auditory canal atresia/stenosis was observed in 61.0% of the cases. Most had conductive hearing loss (75.5%) and imaging study revealed middle/inner ear malformations in 21.1% of the cases. Regarding nonotological characteristics, ophthalmological, osteoarticular and cardiac involvement were the 3 most frequently observed. Most cases had no evident cause for the development of anomalies (68.4%). However, in 16.7% a positive family history was identified. A history of drug intake has been elicited in 14.9% of the participants. The drugs intake during pregnancy found in our study were: isotretinoin, fluoxetine, oral contraceptives, levothyroxine, domperidone, enalapril, acyclovir and pseudoephedrine/triprolidine and gestational diabetes in need of treatment. Conclusion Some drugs are unquestionably associated with the development of malformation, such as isotretinoin, however, the other drugs cannot be underestimated, since their synergistic effect with other environmental agents and genetic background may be in the origin of OAVS.
{"title":"Oculo-auriculo-vertebral spectrum and maternal drug ingestion: cause or coincidence?","authors":"J. Costa, M. Coutinho, T. Soares, Luís Meireles","doi":"10.1080/21695717.2022.2122331","DOIUrl":"https://doi.org/10.1080/21695717.2022.2122331","url":null,"abstract":"Abstract Introduction Oculo-auriculo-vertebral spectrum (OAVS) is aetiologically/pathogenetically a heterogeneous disorder. This study focuses on investigating of maternal drug intake during pregnancy in OAVS cases. Materials and methods Our sample was composed of 114 paediatric cases of OAVS. For each patient, an evaluation form seeking identity, medical history, pregnancy and family data, physical/dysmorphological findings and results from complementary tests was applied. Through the analysis of all the forms applied, the history of drug exposure/maternal diseases were retrospectively studied. Results The age of the population studied ranged between 1 month and 18 years, the majority being male. Regarding otological features, most had pinna involvement: microtia (86.6%); preauricular appendices (41.6%) and preauricular sinus (15.7%). External auditory canal atresia/stenosis was observed in 61.0% of the cases. Most had conductive hearing loss (75.5%) and imaging study revealed middle/inner ear malformations in 21.1% of the cases. Regarding nonotological characteristics, ophthalmological, osteoarticular and cardiac involvement were the 3 most frequently observed. Most cases had no evident cause for the development of anomalies (68.4%). However, in 16.7% a positive family history was identified. A history of drug intake has been elicited in 14.9% of the participants. The drugs intake during pregnancy found in our study were: isotretinoin, fluoxetine, oral contraceptives, levothyroxine, domperidone, enalapril, acyclovir and pseudoephedrine/triprolidine and gestational diabetes in need of treatment. Conclusion Some drugs are unquestionably associated with the development of malformation, such as isotretinoin, however, the other drugs cannot be underestimated, since their synergistic effect with other environmental agents and genetic background may be in the origin of OAVS.","PeriodicalId":43765,"journal":{"name":"Hearing Balance and Communication","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2022-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84981733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-08-12DOI: 10.1080/21695717.2022.2106411
Razan Al Fakir (Alfakir)
Abstract Objectives. Alzheimer's disease (AD) pathogenesis is widely believed to be driven by the Amyloid-β (Aβ) deposition. A relationship between Aβ deposition and objective measures of vestibular function in cognitively intact older adults with peripheral vestibular disorders had gained previous attention; however, no significant relationship between the two was observed. The aim of this study was to examine the association between chronic subjective dizziness (CSD) and Aβ deposition among older adults who are at risk of AD. Methods. The study included 5707 participants without dementia, enrolled in the Mayo Clinic Study of Ageing with reported dizziness, neuropsychological and cognitive evaluations, and brain imaging at baseline and for every 15-months. Results. A total of 924 ageing adults reported dizziness at baseline. The estimated risk of developing CSD at 10-year was 49%. The CSD group is twice likely to have elevated Aβ deposition (HR = 2.23; p ≤ .001) compared to the control group. After controlling for demographic and other risk factors, CSD was significantly associated with Aβ deposition [HR = 1.8, p ≤ .001]. The status of neuropsychiatric symptoms plays a significant role in this association [HR = 1.0, p ≤ .001]. Conclusion. CSD was associated with Aβ deposition in older adults who are at risk of AD including those without dementia and cognitively unimpaired individuals, and modestly more significant cognitive decline during follow-up. The status of neuropsychiatric symptoms plays a significant role in this association. Screening for and appropriately managing CSD as a risk factor for AD may be warranted.
{"title":"Chronic subjective dizziness among an aging population is associated with amyloid positron emission tomography and neuropsychiatric symptoms","authors":"Razan Al Fakir (Alfakir)","doi":"10.1080/21695717.2022.2106411","DOIUrl":"https://doi.org/10.1080/21695717.2022.2106411","url":null,"abstract":"Abstract Objectives. Alzheimer's disease (AD) pathogenesis is widely believed to be driven by the Amyloid-β (Aβ) deposition. A relationship between Aβ deposition and objective measures of vestibular function in cognitively intact older adults with peripheral vestibular disorders had gained previous attention; however, no significant relationship between the two was observed. The aim of this study was to examine the association between chronic subjective dizziness (CSD) and Aβ deposition among older adults who are at risk of AD. Methods. The study included 5707 participants without dementia, enrolled in the Mayo Clinic Study of Ageing with reported dizziness, neuropsychological and cognitive evaluations, and brain imaging at baseline and for every 15-months. Results. A total of 924 ageing adults reported dizziness at baseline. The estimated risk of developing CSD at 10-year was 49%. The CSD group is twice likely to have elevated Aβ deposition (HR = 2.23; p ≤ .001) compared to the control group. After controlling for demographic and other risk factors, CSD was significantly associated with Aβ deposition [HR = 1.8, p ≤ .001]. The status of neuropsychiatric symptoms plays a significant role in this association [HR = 1.0, p ≤ .001]. Conclusion. CSD was associated with Aβ deposition in older adults who are at risk of AD including those without dementia and cognitively unimpaired individuals, and modestly more significant cognitive decline during follow-up. The status of neuropsychiatric symptoms plays a significant role in this association. Screening for and appropriately managing CSD as a risk factor for AD may be warranted.","PeriodicalId":43765,"journal":{"name":"Hearing Balance and Communication","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2022-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84705942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-08-05DOI: 10.1080/21695717.2022.2102726
Adri Katyayan, Angira Katyayan, Arti Rajput, Manish Chandra, V. Verma, A. Mishra
Abstract Objective To promote tele-audiology, the smartphone online applications (APP) for assessment of hearing function need to be validated. We present our preliminary report of one such APP that we adapted during the active COVID phase of 2021. Methodology A total of 44 patients underwent both pure tone audiometry (PTA) and APP-based hearing assessment. The air conduction thresholds at 500 Hz, 1000 Hz, 2000 Hz, 3000 Hz, 4000 Hz, 6000 Hz and 8000 Hz were noted. Results A significant correlation was seen between the thresholds and paired differences. However, air-conduction (AC) thresholds of either PTA or APP were shown to overshoot each other and right side values were more consistent. Conclusions While suggestions have been made to overcome these inconsistencies, the APP-based hearing assessment is likely to improve tele-audiology as relevant modifications by the manufacturer are incorporated to improve its efficacy.
{"title":"Validation of app-based hearing assessment (H3 hearing test) through smart phone: preliminary trends","authors":"Adri Katyayan, Angira Katyayan, Arti Rajput, Manish Chandra, V. Verma, A. Mishra","doi":"10.1080/21695717.2022.2102726","DOIUrl":"https://doi.org/10.1080/21695717.2022.2102726","url":null,"abstract":"Abstract Objective To promote tele-audiology, the smartphone online applications (APP) for assessment of hearing function need to be validated. We present our preliminary report of one such APP that we adapted during the active COVID phase of 2021. Methodology A total of 44 patients underwent both pure tone audiometry (PTA) and APP-based hearing assessment. The air conduction thresholds at 500 Hz, 1000 Hz, 2000 Hz, 3000 Hz, 4000 Hz, 6000 Hz and 8000 Hz were noted. Results A significant correlation was seen between the thresholds and paired differences. However, air-conduction (AC) thresholds of either PTA or APP were shown to overshoot each other and right side values were more consistent. Conclusions While suggestions have been made to overcome these inconsistencies, the APP-based hearing assessment is likely to improve tele-audiology as relevant modifications by the manufacturer are incorporated to improve its efficacy.","PeriodicalId":43765,"journal":{"name":"Hearing Balance and Communication","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2022-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81063492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-08-02DOI: 10.1080/21695717.2022.2102733
H. Shetty, Suma Raju, Y. Kumar, Sanjana S. Singh
Abstract Objective The cognitive capacity allocates the resources effectively for effortless listening to speech presented in noise. This entity is minimally explored in individuals with noise-induced hearing loss (NIHL); therefore, the listening effort in individuals with NIHL at different signal-to-noise ratios was investigated. Method Forty participants with symmetrical mild sensorineural hearing loss were sub-grouped into control and clinical groups. The listening effort was measured using the dual-task paradigm at four different signal-to-noise conditions. In addition, a gap detection test was used to assess temporal processing ability. Results The repeat and recall scores were reduced with decreased signal-to-noise ratios in each group. These differences were significantly poorer in the clinical group than in the control group. A significant strong positive relation was observed between the recall and repeat scores of both groups for the listening effort tasks. Temporal processing impairment was significantly higher in the clinical group than in the control group. Conclusion Individuals with noise-induced hearing loss exhibit a significant temporal processing impairment that leads to effortful listening than hearing loss alone.
{"title":"Listening effort in individuals with noise-induced hearing loss","authors":"H. Shetty, Suma Raju, Y. Kumar, Sanjana S. Singh","doi":"10.1080/21695717.2022.2102733","DOIUrl":"https://doi.org/10.1080/21695717.2022.2102733","url":null,"abstract":"Abstract Objective The cognitive capacity allocates the resources effectively for effortless listening to speech presented in noise. This entity is minimally explored in individuals with noise-induced hearing loss (NIHL); therefore, the listening effort in individuals with NIHL at different signal-to-noise ratios was investigated. Method Forty participants with symmetrical mild sensorineural hearing loss were sub-grouped into control and clinical groups. The listening effort was measured using the dual-task paradigm at four different signal-to-noise conditions. In addition, a gap detection test was used to assess temporal processing ability. Results The repeat and recall scores were reduced with decreased signal-to-noise ratios in each group. These differences were significantly poorer in the clinical group than in the control group. A significant strong positive relation was observed between the recall and repeat scores of both groups for the listening effort tasks. Temporal processing impairment was significantly higher in the clinical group than in the control group. Conclusion Individuals with noise-induced hearing loss exhibit a significant temporal processing impairment that leads to effortful listening than hearing loss alone.","PeriodicalId":43765,"journal":{"name":"Hearing Balance and Communication","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2022-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90321600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-08-02DOI: 10.1080/21695717.2022.2105554
H. Shetty, Suma Raju
Abstract Objective The temporal envelope enhancement using deep band modulation (DBM) exaggerates the temporal peaks and valleys in the speech signal, thereby reducing the difficulty in the perception of speech in noise. Method Ten participants in each group of older adults with and without hearing loss in 65 to 83 years were recruited. A repeated measures research design was utilised to investigate phrase perception in unprocessed and deep band modulated phrases at different signal-to-noise (SNR) ratios (−4, 0, and +4). Temporal processing, spectral discrimination and speech intelligibility index were assessed. Results Regardless of the group, the phrase perception in the deep band modulated condition was significantly better than the unprocessed condition at each SNR. A significantly strong negative correlation was observed between: Gap detection threshold (GDT) and phrase perception scores in unprocessed condition at −4 dB SNR in each group; frequency difference limen in each condition and DBM phrase perception at −4 dB SNR in the older adult group with hearing impaired (OAG-HI) group. Furthermore, audibility reflected in the speech intelligibility index (SII) did not influence phrase recognition irrespective of condition, SNRs and group. Conclusion Increased modulation depth enables the participants to use the available temporal envelope, especially at the portion of the phrase where noise is less energetically masked.
{"title":"Deep band modulation, frequency discrimination, temporal resolution and audibility effects: phrase perception with and without hearing impairment among older adults","authors":"H. Shetty, Suma Raju","doi":"10.1080/21695717.2022.2105554","DOIUrl":"https://doi.org/10.1080/21695717.2022.2105554","url":null,"abstract":"Abstract Objective The temporal envelope enhancement using deep band modulation (DBM) exaggerates the temporal peaks and valleys in the speech signal, thereby reducing the difficulty in the perception of speech in noise. Method Ten participants in each group of older adults with and without hearing loss in 65 to 83 years were recruited. A repeated measures research design was utilised to investigate phrase perception in unprocessed and deep band modulated phrases at different signal-to-noise (SNR) ratios (−4, 0, and +4). Temporal processing, spectral discrimination and speech intelligibility index were assessed. Results Regardless of the group, the phrase perception in the deep band modulated condition was significantly better than the unprocessed condition at each SNR. A significantly strong negative correlation was observed between: Gap detection threshold (GDT) and phrase perception scores in unprocessed condition at −4 dB SNR in each group; frequency difference limen in each condition and DBM phrase perception at −4 dB SNR in the older adult group with hearing impaired (OAG-HI) group. Furthermore, audibility reflected in the speech intelligibility index (SII) did not influence phrase recognition irrespective of condition, SNRs and group. Conclusion Increased modulation depth enables the participants to use the available temporal envelope, especially at the portion of the phrase where noise is less energetically masked.","PeriodicalId":43765,"journal":{"name":"Hearing Balance and Communication","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2022-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77200633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abstract Objective Congenital hearing loss is a disabling and multi-factorial disease that affects on newborn and children. This study aims to demonstrate the relationship between risk factors for hearing loss and the results of Otoacoustic emission in Iranian newborns. Methods We have retrospectively considered 536 newborns admitted to the Audiology Department of a Children’s Hospital in the north of Iran. Transient Evoked Otoacoustic Emissions (TEOAEs) was recorded during the first week of birth, and the risk factors of hearing loss were collected. Results We found that parent relatives and family history were significantly correlated with OAEs refer results. Moreover, hyper-bilirubinemia indicated a significant correlation only with first right OAEs. There was a significant correlation between gender and first left and right OAEs. Other risk factors such as seizure, transient tachypnoea of the newborn (TTN) and respiratory distress syndrome (RDS), and lip cleft had a significant correlation with first left and right OAEs results; however, these correlations were not relatively highlighted. Conclusions Generally, our data confirm that hearing screening is an absolute necessity in the greater number of newborns. People who got consanguineous marriages should be aware of high incidence of the congenital hearing loss due to parent relatives and family history.
{"title":"Relationship between risk factors of hearing loss and the results of otoacoustic emission in newborns","authors":"Fereshteh Bagheri, Zeinab Miresmaeili, Mousa Ahmadpour-Kacho, Zohreh Ziatabar Ahmadi","doi":"10.1080/21695717.2022.2102727","DOIUrl":"https://doi.org/10.1080/21695717.2022.2102727","url":null,"abstract":"Abstract Objective Congenital hearing loss is a disabling and multi-factorial disease that affects on newborn and children. This study aims to demonstrate the relationship between risk factors for hearing loss and the results of Otoacoustic emission in Iranian newborns. Methods We have retrospectively considered 536 newborns admitted to the Audiology Department of a Children’s Hospital in the north of Iran. Transient Evoked Otoacoustic Emissions (TEOAEs) was recorded during the first week of birth, and the risk factors of hearing loss were collected. Results We found that parent relatives and family history were significantly correlated with OAEs refer results. Moreover, hyper-bilirubinemia indicated a significant correlation only with first right OAEs. There was a significant correlation between gender and first left and right OAEs. Other risk factors such as seizure, transient tachypnoea of the newborn (TTN) and respiratory distress syndrome (RDS), and lip cleft had a significant correlation with first left and right OAEs results; however, these correlations were not relatively highlighted. Conclusions Generally, our data confirm that hearing screening is an absolute necessity in the greater number of newborns. People who got consanguineous marriages should be aware of high incidence of the congenital hearing loss due to parent relatives and family history.","PeriodicalId":43765,"journal":{"name":"Hearing Balance and Communication","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2022-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86349467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abstract Objective(s) In this study, it was aimed to evaluate the weakness in postural balance skills that occurred between the ages of 40–55 by comparing vestibulospinal tests and static posturography tests. Methods A total of 40 healthy individuals between the ages of 18–30 (mean: 23.8 ± 3.05 years) and 40–55 (mean: 49.2 ± 6.4 years) who voluntarily agreed to participate in the study, without vertigo and balance problems were included. As being objective vestibulospinal tests, the modified clinical test of sensory interaction and balance (mCTSIB) and Limits of Stability (LOS) tests were performed using a static posturography device. Tandem Romberg, Fukuda Stepping Test (FST) and Babinski–Weil tests were performed as subjective vestibulospinal tests. Results Compared with the younger group, 40–55 ages showed significant weakness in movement velocity (MVL), endpoint excursions (EPEs), maximum excursions sub-parameters of LOS, in all eyes-closed subtests in the mCTSIB test, and in subjective vestibulospinal tests. No relationship between vestibulospinal and static posturography was observed. Conclusions Contrary to popular belief, the effect on the age-related balance system begins earlier. When the middle age group applies to ENT clinics with complaints of imbalance, it should be taken into account that age-related effects may occur.
{"title":"Vestibulospinal system findings caused by ageing between 40 and 55 years","authors":"Ozlem Konukseven, Sema Satici, Inci Adali, Yagmur Yildiz, Lena Dogru, Sencan Duruoglu","doi":"10.1080/21695717.2022.2087310","DOIUrl":"https://doi.org/10.1080/21695717.2022.2087310","url":null,"abstract":"Abstract Objective(s) In this study, it was aimed to evaluate the weakness in postural balance skills that occurred between the ages of 40–55 by comparing vestibulospinal tests and static posturography tests. Methods A total of 40 healthy individuals between the ages of 18–30 (mean: 23.8 ± 3.05 years) and 40–55 (mean: 49.2 ± 6.4 years) who voluntarily agreed to participate in the study, without vertigo and balance problems were included. As being objective vestibulospinal tests, the modified clinical test of sensory interaction and balance (mCTSIB) and Limits of Stability (LOS) tests were performed using a static posturography device. Tandem Romberg, Fukuda Stepping Test (FST) and Babinski–Weil tests were performed as subjective vestibulospinal tests. Results Compared with the younger group, 40–55 ages showed significant weakness in movement velocity (MVL), endpoint excursions (EPEs), maximum excursions sub-parameters of LOS, in all eyes-closed subtests in the mCTSIB test, and in subjective vestibulospinal tests. No relationship between vestibulospinal and static posturography was observed. Conclusions Contrary to popular belief, the effect on the age-related balance system begins earlier. When the middle age group applies to ENT clinics with complaints of imbalance, it should be taken into account that age-related effects may occur.","PeriodicalId":43765,"journal":{"name":"Hearing Balance and Communication","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2022-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72921768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-07-03DOI: 10.1080/21695717.2022.2084866
Arnaud Coëz, N. Loundon, I. Rouillon, M. Parodi, M. Blanchard, S. Achard, E. Garabédian, E. Bizaguet, Tabassome Simon, N. Tessier, F. Denoyelle, J. Gervain
Abstract Purpose: Deafness in infancy has longlasting consequences on brain organization. To achieve the best developmental outcomes in case of profound deafness, cochlear implantation (CI) needs to take place in a critical period during the first year of life, before the cross-modal reorganization of the brain due to auditory deprivation stabilises, preventing the typical development of the auditory cortices. Despite its importance for implantation outcomes, the nature of this critical period and the underlying neural reorganization have not been fully explored. Materials and methods: To fill this knowledge gap, we investigated the cortical responses of 12-month-old profoundly deaf infants and their age-matched controls to sounds produced by a human voice as compared to non-human sounds using functional near-infrared spectroscopy (fNIRS). The deaf infants were tested before undergoing CI surgery and wore hearing aids, allowing them to perceive low frequencies. Human voice stimuli have been shown to trigger brain responses early in development, possibly due to its evolutionary relevance for survival. Results: We found increased brain responses to the human voice in the deaf infants in the bilateral fronto-temporal areas, and their responses correlated with their residual hearing thresholds. These results suggest that even the limited sound stimulation that these deaf infants receive due to their residual hearing allowed the temporal cortices to develop sensitivity to the human voice prior to implantation. The hearing control group showed an inverted hemodynamic response to both voice and non-voice stimuli in the left parietal and right temporal areas, suggesting that by 12 months of age, they habituate rapidly to these very familiar stimuli. While both groups showed an inverted response to the non-voice stimuli, they differed in their responses to voice stimuli. Conclusions: We hypothesize that the responses found in deaf infants to human voice can be consider a good cochlear implant prognosis.
{"title":"The recognition of human voice in deaf and hearing infants","authors":"Arnaud Coëz, N. Loundon, I. Rouillon, M. Parodi, M. Blanchard, S. Achard, E. Garabédian, E. Bizaguet, Tabassome Simon, N. Tessier, F. Denoyelle, J. Gervain","doi":"10.1080/21695717.2022.2084866","DOIUrl":"https://doi.org/10.1080/21695717.2022.2084866","url":null,"abstract":"Abstract Purpose: Deafness in infancy has longlasting consequences on brain organization. To achieve the best developmental outcomes in case of profound deafness, cochlear implantation (CI) needs to take place in a critical period during the first year of life, before the cross-modal reorganization of the brain due to auditory deprivation stabilises, preventing the typical development of the auditory cortices. Despite its importance for implantation outcomes, the nature of this critical period and the underlying neural reorganization have not been fully explored. Materials and methods: To fill this knowledge gap, we investigated the cortical responses of 12-month-old profoundly deaf infants and their age-matched controls to sounds produced by a human voice as compared to non-human sounds using functional near-infrared spectroscopy (fNIRS). The deaf infants were tested before undergoing CI surgery and wore hearing aids, allowing them to perceive low frequencies. Human voice stimuli have been shown to trigger brain responses early in development, possibly due to its evolutionary relevance for survival. Results: We found increased brain responses to the human voice in the deaf infants in the bilateral fronto-temporal areas, and their responses correlated with their residual hearing thresholds. These results suggest that even the limited sound stimulation that these deaf infants receive due to their residual hearing allowed the temporal cortices to develop sensitivity to the human voice prior to implantation. The hearing control group showed an inverted hemodynamic response to both voice and non-voice stimuli in the left parietal and right temporal areas, suggesting that by 12 months of age, they habituate rapidly to these very familiar stimuli. While both groups showed an inverted response to the non-voice stimuli, they differed in their responses to voice stimuli. Conclusions: We hypothesize that the responses found in deaf infants to human voice can be consider a good cochlear implant prognosis.","PeriodicalId":43765,"journal":{"name":"Hearing Balance and Communication","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2022-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87950023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-07-03DOI: 10.1080/21695717.2022.2105599
J. Gervain, P. Trevisi
{"title":"Editorial to the Monographic Issue: The development of hearing and language during the first years of life","authors":"J. Gervain, P. Trevisi","doi":"10.1080/21695717.2022.2105599","DOIUrl":"https://doi.org/10.1080/21695717.2022.2105599","url":null,"abstract":"","PeriodicalId":43765,"journal":{"name":"Hearing Balance and Communication","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2022-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76540424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-06-22DOI: 10.1080/21695717.2022.2083787
P. Sethukumar, N. Amin, A. Hall, R. Nash
Abstract Objective To review trends in outcome domains and instruments reported by modern researchers in 100 consecutively published articles on cochlear implantation (CI). Methods Retrograde literature review of Medline, EMBASE and Cochrane Databases of 100 consecutive scientific publications. Outcome domains and instruments from each included study were extracted in categories: speech perception, speech development, sound perception, electrophysiological and quality of life. Results 61 studies met inclusion criteria. 84 outcome measures were reported in total across all 61 studies. Across the 42 studies reporting speech perception, 31 different measures were utilised. Categories of Auditory Performance (CAP) and Consonant Nucleus Consonant (CNC) were the most frequently used instruments. Nine studies reported speech development, with 11 different instruments used. Speech Intelligibility Rating (SIR) was most frequently used instrument. Sixteen studies reported on sound perception, with Pure Tone Audiometry (PTA) being the most frequently used instrument. Eleven studies reported six different electrophysiological instruments, with Auditory Brainstem Response (ABR) being used most frequently used. Two studies measured quality of life outcome, with three instruments used. Conclusion This study confirms a large degree of CI outcome heterogeneity within the peer reviewed literature. Determining consensus on core outcome domains and recommended instruments may increase the future impact and generalisability of work undertaken.
{"title":"Publication trends in cochlear implantation outcome measures","authors":"P. Sethukumar, N. Amin, A. Hall, R. Nash","doi":"10.1080/21695717.2022.2083787","DOIUrl":"https://doi.org/10.1080/21695717.2022.2083787","url":null,"abstract":"Abstract Objective To review trends in outcome domains and instruments reported by modern researchers in 100 consecutively published articles on cochlear implantation (CI). Methods Retrograde literature review of Medline, EMBASE and Cochrane Databases of 100 consecutive scientific publications. Outcome domains and instruments from each included study were extracted in categories: speech perception, speech development, sound perception, electrophysiological and quality of life. Results 61 studies met inclusion criteria. 84 outcome measures were reported in total across all 61 studies. Across the 42 studies reporting speech perception, 31 different measures were utilised. Categories of Auditory Performance (CAP) and Consonant Nucleus Consonant (CNC) were the most frequently used instruments. Nine studies reported speech development, with 11 different instruments used. Speech Intelligibility Rating (SIR) was most frequently used instrument. Sixteen studies reported on sound perception, with Pure Tone Audiometry (PTA) being the most frequently used instrument. Eleven studies reported six different electrophysiological instruments, with Auditory Brainstem Response (ABR) being used most frequently used. Two studies measured quality of life outcome, with three instruments used. Conclusion This study confirms a large degree of CI outcome heterogeneity within the peer reviewed literature. Determining consensus on core outcome domains and recommended instruments may increase the future impact and generalisability of work undertaken.","PeriodicalId":43765,"journal":{"name":"Hearing Balance and Communication","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2022-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80456686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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