NUCLEAR MEDICINE REVIEW最新文献

{"title":"Presentation of genital tuberculosis detected on FDG PET/CT scan resembling a primary gynecologic tumor and metastases.","authors":"Inci Uslu Biner,&nbsp;Ebru Tatci,&nbsp;Ozlem Ozmen,&nbsp;Mujgan Güler,&nbsp;Fatma Benli","doi":"10.5603/NMR.2021.0022","DOIUrl":"https://doi.org/10.5603/NMR.2021.0022","url":null,"abstract":"<p><p>Gastric cancer (GC) is a common cause of cancer-related deaths in the world. In addition to the patient's clinical history and clinical examination, nuclear medicine tools are required for diagnosis. [¹⁸F]FDG PET/CT has been commonly used for cancer patients for staging, restaging, evaluation of treatment response. This study aimed to review the current literature on the role of [¹⁸F]FDG PET/CT for GC management.</p>","PeriodicalId":44718,"journal":{"name":"NUCLEAR MEDICINE REVIEW","volume":"24 2","pages":"104-105"},"PeriodicalIF":0.9,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39303514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sentinel lymph node biopsy in upper tract urothelial cancers: an experience with intraoperative radiotracer injection.","authors":"Leili Zarifmahmoudi,&nbsp;Hamidreza Ghorbani,&nbsp;Ramin Sadeghi,&nbsp;Salman Soltani,&nbsp;Kayvan Sadri,&nbsp;Mahmoud Tavakkoli,&nbsp;Maliheh Keshvari","doi":"10.5603/NMR.2021.0013","DOIUrl":"https://doi.org/10.5603/NMR.2021.0013","url":null,"abstract":"<p><strong>Background: </strong>The feasibility of the sentinel node mapping in upper tract urothelial cancers (UTUC) was evaluated, using a radiotracer as the mapping material.</p><p><strong>Material and methods: </strong>To identify the sentinel lymph nodes, 37 MBq of [99mTc] phytate was injected in five patients with the renal pelvis or ureter cancer, who were candidates for ureterectomy and lymphadenectomy. The radiotracer was injected in a peritumoral fashion following the surgical exposure of the tumour. The sentinel lymph nodes were detected using a handheld gamma probe.</p><p><strong>Results: </strong>By intraoperatively injecting the radiotracer immediately after surgical exposure of the tumour, at least one sentinel lymph node could be detected in each patient, and the detection rate was 100%. The location of sentinel nodes was in the paracaval, renal hill, retro-aortic, para-aortic, common iliac, and external iliac areas, which was dependent on the tumour location. No false-negative case was identified.</p><p><strong>Conclusions: </strong>Sentinel node mapping is feasible in UTUC. Injection technique (intra-vesical approach vs peri-tumoral injection after exposure of the tumour) and location of the tumour (proximal vs distal) may affect the technique's feasibility.</p>","PeriodicalId":44718,"journal":{"name":"NUCLEAR MEDICINE REVIEW","volume":"24 2","pages":"41-45"},"PeriodicalIF":0.9,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39303545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cholethorax with biliopleural communication detected on [99mTc]mebrofenin hepatobiliary scintigraphy.","authors":"Georgios Meristoudis,&nbsp;Ioannis Ilias,&nbsp;Evangelia Zaromytidou,&nbsp;Emmanouil Alevroudis,&nbsp;Athanasios Notopoulos","doi":"10.5603/NMR.2021.0031","DOIUrl":"https://doi.org/10.5603/NMR.2021.0031","url":null,"abstract":"<p><p>Bilious pleural effusion or cholethorax is a rare type of exudative pleural effusion. Here is presented a case of right-sided cholethorax, in which the direct communication between the pleural effusion with the biliary duct was visible only on the posteriori images of dynamic hepatobiliary scintigraphy with [99mTc]mebrofenin.</p>","PeriodicalId":44718,"journal":{"name":"NUCLEAR MEDICINE REVIEW","volume":"24 2","pages":"124-125"},"PeriodicalIF":0.9,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39313950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lung perfusion SPECT/CT images associated with COVID-19 - a case series.","authors":"Sara Kurkowska,&nbsp;Hanna Piwowarska-Bilska,&nbsp;Jacek Iwanowski,&nbsp;Bozena Birkenfeld","doi":"10.5603/NMR.2021.0009","DOIUrl":"https://doi.org/10.5603/NMR.2021.0009","url":null,"abstract":"Coronavirus disease 2019 (COVID-19) most often presents with mild symptoms, but it can also present with viral pneumonia and acute respiratory distress syndrome, which predispose to thromboembolic disease. There is an increasing number of case studies which report the significance of ventilation/perfusion scintigraphy in the diagnosis of pulmonary embolism in COVID-19 patients [1, 2]. Since most of the patients in Poland were managed in an outpatient setting, this population has been excluded from many studies and its characteristics are not well-documented. Dhawan et al. [3] emphasize the importance of the evaluation of the prevalence and extent of perfusion abnormalities in survivors of COVID-19 through the whole spectrum of illness, from non-hospitalised patients to those in the intensive care unit (ICU). We report a case series of three patients after recovery from COVID-19, who underwent lung perfusion SPECT/CT. Scintigraphic examinations were performed after administration of 99mTc-Makro-Albumon with an activity of about 2 MBq/kg of patient’s body weight. All patients were examined using Symbia Intevo Bold with a protocol including SPECT/CT acquisition with the following parameters: LEHR collimator, 360 degrees, 120 projections, time per projection 15 sec, matrix 128x128; low-dose CT protocol. The examinations were performed to assess lung lesions in these patients. All patients were diagnosed through RT-PCR for SARS-CoV2 and were presenting mild-to-moderate symptoms. Treatment was symptomatic, including paracetamol and ibuprofen in all patients and additional azithromycin in case of Patient 1. None of them required hospitalization. Data and perfusion SPECT/CT findings of the patients are presented in the Table 1 below. Figure 1 and 2 show SPECT/CT findings of Patients 1 and 3, respectively.","PeriodicalId":44718,"journal":{"name":"NUCLEAR MEDICINE REVIEW","volume":"24 1","pages":"35-36"},"PeriodicalIF":0.9,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25364678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In memoriam - Prof. Anna Celler.","authors":"Bozena Birkenfeld,&nbsp;Renata Mikolajczak","doi":"10.5603/NMR.2021.0011","DOIUrl":"https://doi.org/10.5603/NMR.2021.0011","url":null,"abstract":"","PeriodicalId":44718,"journal":{"name":"NUCLEAR MEDICINE REVIEW","volume":"24 1","pages":"37-39"},"PeriodicalIF":0.9,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25364679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editorial.","authors":"Grzegorz Kamiński","doi":"10.5603/NMR.2021.0010","DOIUrl":"https://doi.org/10.5603/NMR.2021.0010","url":null,"abstract":"","PeriodicalId":44718,"journal":{"name":"NUCLEAR MEDICINE REVIEW","volume":"24 1","pages":""},"PeriodicalIF":0.9,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25364670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the usefulness of positron emission tomography with [18F]fluorodeoxylglucose performed to detect non-radioiodine avid recurrence and/or metastasis of differentiated thyroid cancer - a preliminary study.","authors":"Maciej Kolodziej,&nbsp;Marek Saracyn,&nbsp;Arkadiusz Lubas,&nbsp;Dorota Brodowska-Kania,&nbsp;Andrzej Mazurek,&nbsp;Mirosław Dziuk,&nbsp;Jolanta Dymus,&nbsp;Grzegorz Kaminski","doi":"10.5603/NMR.2021.0017","DOIUrl":"https://doi.org/10.5603/NMR.2021.0017","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;About 30% of patients with disseminated differentiated thyroid cancer (DTC) may experience a loss of iodine uptake. It is associated with higher aggressiveness of the tumour and a reduced 10-year survival rate. The diagnosis of non-radioiodine avid DTC metastases remains a diagnostic challenge. A helpful technique for this diagnosis is positron emission tomography with 2-[¹⁸F]fluoro-2-deoxy-D-glucose (PET/CT with [¹⁸F]FDG). On the other hand, there are still discussions about the clinical value of using exogenous thyroid-stimulating hormone (TSH) stimulation before PET/CT with [¹⁸F]FDG. The aim of the study was the assessment of the usefulness of PET/CT with [¹⁸F]FDG under TSH suppression and stimulation of TSH performed in the detection of non-radioiodine avid DTC metastases, as well as determination of the thyroglobulin concentration under suppression and stimulation of TSH, which influences the result of PET/CT with [¹⁸F]FDG in patients with non-radioiodine avid DTC.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Material and methods: &lt;/strong&gt;Retrospective analysis of 37 PET/CT with [¹⁸F]FDG performed in patients with DTC diagnosed and treated at the Department of Endocrinology and Isotope Therapy of the Military Institute of Medicine from January 2018 to July 2020. Of these, PET/CT with [¹⁸F]FDG under exogenous rhTSH stimulation was performed in 22 patients and PET/CT with [¹⁸F]FDG under TSH suppression in 15 was performed. In all analyzed patients, the result of diagnostic whole-body scintigraphy (WBS) using 80 MBq ¹³¹I under rhTSH stimulation was negative, and the concentration of thyroglobulin after stimulation (sTg) was greater than 1.0 ng/mL.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;In the group of patients examined under TSH suppression, non-radioiodine avid in PET/CT with [¹⁸F]FDG were found in 6 out of 15 patients (40%) and in the group of patients examined under rhTSH stimulation in 10 out of 22 patients (45%). The differences between the groups were not statistically significant. The analysis of the receiver operating characteristic (ROC) curves allowed to determine the cut-off point for the positive result of PET/CT performed under TSH suppression with sTg concentration of 11.03 ng/mL. In the group of studies performed under rhTSH stimulation, the cut-off point for sTg was 6.3 ng/mL. There was no statistically significant difference between the baseline thyroglobulin (natTg) and sTg levels and the positive PET/CT result. The administration of rhTSH before the PET/CT examination also had no statistically significant effect on the maximum standard uptake value (SUVmax) of the dominant lesion identified in the PET/CT.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions: &lt;/strong&gt;1) PET/CT with [¹⁸F]FDG is a useful tool for detection of non-radioiodine avid recurrence and/or metastases of DTC. 2) The concentration of natTg and sTg is highly correlated with a positive result of PET/CT with [¹⁸F]FDG. 3) The concentration of natTg is comparable with sTg in predicting a pos","PeriodicalId":44718,"journal":{"name":"NUCLEAR MEDICINE REVIEW","volume":"24 2","pages":"63-69"},"PeriodicalIF":0.9,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39303508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Infection of aortobifemoral bypass graft implanted 20 years ago proved by labeled leukocytes SPECT-CT.","authors":"Olgierd Chrabanski,&nbsp;Tomasz Golab","doi":"10.5603/NMR.a2021.0027","DOIUrl":"https://doi.org/10.5603/NMR.a2021.0027","url":null,"abstract":"Correspondence to: Olgierd Chrabanski, Department of Radiodiagnostics, Invasive Radiology and Nuclear Medicine, Faculty of Medical Sciences in Katowice, Medical University of Silesia, Katowice, Poland, e-mail: olgierdchrabanski@gmail.com Aortic graft infections are very serious complications of arterial reconstructive surgery. The described in literature longest interval between primary reconstruction and aortic graft infections was 20 years [1]. This research reports a case of a 60-year-old man with a suspected infection of an aortobifemoral bypass graft implanted 20 years ago due to an aneurysm of the abdominal aorta. He was referred to a nuclear medicine department for scintigraphic detection or exclusion of active infection within the stent-graft. The patient had many comorbidities: renal failure, arterial hypertension, hypertensive cardiomyopathy, ischemic heart disease. This year, the patient underwent thrombosis of the left saphenous vein with cellulitis of the left leg and was treated surgically due to an abscess of the left buttock. Laboratory tests revealed: leukocytosis, significantly elevated CRP and anaemia. Enterococcus faecalis susceptible to ampicillin, teicoplanin and vancomycin were grown on venous blood cultures. Despite the implementation of antibiotic therapy, no significant improvement in the patient’s clinical condition was achieved. The computed tomography examination showed changes suggesting infection of the vascular prosthesis. Due to the high risk of the surgery, it was decided to operate after obtaining scintigraphic detection of infection within the stentgraft. The examination was performed with Technetium-99m labelled leukocytes using HMPAO. The patient was examined 1, 4 and 24 hours after radiotracer injection using Symbia Intevo with a protocol including SPECT/CT with LEHR collimator, low-dose CT.","PeriodicalId":44718,"journal":{"name":"NUCLEAR MEDICINE REVIEW","volume":"24 2","pages":"115-117"},"PeriodicalIF":0.9,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39313949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Accumulation of 99m-Tc Phytate in the pyelocalyceal system in a patient with chylous ascites - a pitfall resolved by SPECT/CT.","authors":"Hadis Mohammadzadeh Kosari, Somayeh Barashki, Yasaman Fakhar, Emran Askari, Ramin Sadeghi","doi":"10.5603/NMR.2021.0006","DOIUrl":"10.5603/NMR.2021.0006","url":null,"abstract":"<p><p>We reported 99m-Tc phytate accumulation in the pyelocalyceal system of the kidney in the lymphoscintigraphic images of a 3.5 months-old male infant with chylous ascites, which was mistaken with the site of lymph leakage. SPECT/CT localized activity in the para-aortic region to the renal pelvis and on delayed images, this was disappeared. Our case illustrates the added value of SPECT/CT for the differentiation of possible false-positive findings in lymphoscintigraphy.</p>","PeriodicalId":44718,"journal":{"name":"NUCLEAR MEDICINE REVIEW","volume":"24 1","pages":"29-30"},"PeriodicalIF":0.6,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25364675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fever of Unknown Origin - infected Fistula-in-Ano as the focus on 18F-FDG PET-CT.","authors":"Punit Sharma","doi":"10.5603/NMR.2021.0007","DOIUrl":"10.5603/NMR.2021.0007","url":null,"abstract":"<p><p>Fever of Unknown Origin (FUO) is a vexing clinical problem. Diagnosis of aetiology is essential for definitive management. A wide array of infective, inflammatory, malignant and miscellaneous pathologies can cause FUO. Hybrid imaging with 18F-Fluorodeoxyglucose (18F-FDG) positron emission tomography-computed tomography (PET-CT) is now an integral part of FUO management because of its ability to demonstrate the cause in a large proportion of cases. The authors present the case of a 42-year-old male, where an infected fistula-in-ano was detected as the cause of FUO on 18F-FDG PET-CT.</p>","PeriodicalId":44718,"journal":{"name":"NUCLEAR MEDICINE REVIEW","volume":"24 1","pages":"31-32"},"PeriodicalIF":0.6,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25364676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}