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C63. MECHANISTIC STUDIES IN COPD最新文献

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Multiple Single Nucleotide Polymorphisms (SNPs) of the Transient Receptor Potential Vanilloid 1 (TRPV1) Genes Are Associated with Cough Response to Capsaicin in Healthy Subjects 瞬时受体电位香草素1 (TRPV1)基因的多个单核苷酸多态性与健康受试者对辣椒素的咳嗽反应相关
C63. MECHANISTIC STUDIES IN COPD
Pub Date : 2019-05-01 DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a7434
P. Maestrelli, F. Liviero, M. Campisi, S. Pavanello
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引用次数: 1
Shared Single Nucleotide Polymorphisms Regulate Gene Expression of Macrophage Migration Inhibitory Factor and D-Dopachrome Tautomerase-Like Protein in Lung Tissue 共享单核苷酸多态性调控肺组织巨噬细胞迁移抑制因子和d -多巴胺互变酶样蛋白的基因表达
C63. MECHANISTIC STUDIES IN COPD
Pub Date : 2019-05-01 DOI: 10.1164/AJRCCM-CONFERENCE.2019.199.1_MEETINGABSTRACTS.A5388
L. F. Sampedro, C. Brandsma, M. D. Vries, W. Timens, M. Obeidat, P. Joubert, D. Nickle, G. Poelarends, A. Faiz, B. Melgert
{"title":"Shared Single Nucleotide Polymorphisms Regulate Gene Expression of Macrophage Migration Inhibitory Factor and D-Dopachrome Tautomerase-Like Protein in Lung Tissue","authors":"L. F. Sampedro, C. Brandsma, M. D. Vries, W. Timens, M. Obeidat, P. Joubert, D. Nickle, G. Poelarends, A. Faiz, B. Melgert","doi":"10.1164/AJRCCM-CONFERENCE.2019.199.1_MEETINGABSTRACTS.A5388","DOIUrl":"https://doi.org/10.1164/AJRCCM-CONFERENCE.2019.199.1_MEETINGABSTRACTS.A5388","url":null,"abstract":"","PeriodicalId":448051,"journal":{"name":"C63. MECHANISTIC STUDIES IN COPD","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116179034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Chymotrypsin-Like Elastase 1 Is Required for Late Lung Remodeling in Mouse Porcine Pancreatic Elastase Model of Emphysema 胰凝乳蛋白酶样弹性酶1在猪肺气肿胰腺弹性酶模型晚期肺重构中起重要作用
C63. MECHANISTIC STUDIES IN COPD
Pub Date : 2019-05-01 DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a5365
M. Ojha, R. Joshi, J. Lewis, F. Qiang, B. Varisco
{"title":"Chymotrypsin-Like Elastase 1 Is Required for Late Lung Remodeling in Mouse Porcine Pancreatic Elastase Model of Emphysema","authors":"M. Ojha, R. Joshi, J. Lewis, F. Qiang, B. Varisco","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a5365","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a5365","url":null,"abstract":"","PeriodicalId":448051,"journal":{"name":"C63. MECHANISTIC STUDIES IN COPD","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134005505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prioritizing GWAS SNPs to Guide Functional Genomics of Human Lung Disease 优先考虑GWAS snp以指导人类肺部疾病的功能基因组学
C63. MECHANISTIC STUDIES IN COPD
Pub Date : 2019-05-01 DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a7435
B. Stubbs, S. Gopaulakrishnan, Damien C. Croteau-Chonka, K. Glass, V. Carey, B. Raby
{"title":"Prioritizing GWAS SNPs to Guide Functional Genomics of Human Lung Disease","authors":"B. Stubbs, S. Gopaulakrishnan, Damien C. Croteau-Chonka, K. Glass, V. Carey, B. Raby","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a7435","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a7435","url":null,"abstract":"","PeriodicalId":448051,"journal":{"name":"C63. MECHANISTIC STUDIES IN COPD","volume":"39 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132906565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Functional Characterization of Alveolar Macrophages (AM) Derived from Alpha-1 Antitrypsin (AAT) Deficient (AATD) Human Induced Pluripotent Stem Cells α -1抗胰蛋白酶(AAT)缺陷(AATD)人诱导多能干细胞衍生的肺泡巨噬细胞(AM)的功能表征
C63. MECHANISTIC STUDIES IN COPD
Pub Date : 2019-05-01 DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a7426
A. Mikosz, D. Cao, A. Wilson, D. Kotton, I. Petrache, K. Serban
{"title":"Functional Characterization of Alveolar Macrophages (AM) Derived from Alpha-1 Antitrypsin (AAT) Deficient (AATD) Human Induced Pluripotent Stem Cells","authors":"A. Mikosz, D. Cao, A. Wilson, D. Kotton, I. Petrache, K. Serban","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a7426","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a7426","url":null,"abstract":"","PeriodicalId":448051,"journal":{"name":"C63. MECHANISTIC STUDIES IN COPD","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130706819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
NEIL2 Activity a Sign of Oxidative Stress in COPD? NEIL2活性是COPD患者氧化应激的标志?
C63. MECHANISTIC STUDIES IN COPD
Pub Date : 2019-05-01 DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a5383
J. Seashore, N. Tapryal, S. Sur, T. Hazra, V. Cardenas
{"title":"NEIL2 Activity a Sign of Oxidative Stress in COPD?","authors":"J. Seashore, N. Tapryal, S. Sur, T. Hazra, V. Cardenas","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a5383","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a5383","url":null,"abstract":"","PeriodicalId":448051,"journal":{"name":"C63. MECHANISTIC STUDIES IN COPD","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125308811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Unsupervised Clustering Reveals Distinct Macrophage Phenotypes Associated with COPD and COPD Exacerbation 无监督聚类揭示与COPD和COPD加重相关的不同巨噬细胞表型
C63. MECHANISTIC STUDIES IN COPD
Pub Date : 2019-05-01 DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a7436
S. Vasudevan, J. Vásquez, W. E. Chen, E. Niemi, S. Zeng, M. Arjomandi
{"title":"Unsupervised Clustering Reveals Distinct Macrophage Phenotypes Associated with COPD and COPD Exacerbation","authors":"S. Vasudevan, J. Vásquez, W. E. Chen, E. Niemi, S. Zeng, M. Arjomandi","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a7436","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a7436","url":null,"abstract":"","PeriodicalId":448051,"journal":{"name":"C63. MECHANISTIC STUDIES IN COPD","volume":"9 6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124266512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Regulation of NADPH Oxidase Activity by the Protease Inhibitor Alpha-1 Antitrypsin, a Novel Mechanism 蛋白酶抑制剂α -1抗胰蛋白酶调节NADPH氧化酶活性的新机制
C63. MECHANISTIC STUDIES IN COPD
Pub Date : 2019-05-01 DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a5366
P. Hawkins, D. Bergin, T. McEnery, N. McElvaney, E. Reeves
{"title":"The Regulation of NADPH Oxidase Activity by the Protease Inhibitor Alpha-1 Antitrypsin, a Novel Mechanism","authors":"P. Hawkins, D. Bergin, T. McEnery, N. McElvaney, E. Reeves","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a5366","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a5366","url":null,"abstract":"","PeriodicalId":448051,"journal":{"name":"C63. MECHANISTIC STUDIES IN COPD","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129564493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Elastase Activity as an Indicator of Exacerbation and Disease Severity in COPD 弹性酶活性作为慢性阻塞性肺病加重和疾病严重程度的指标
C63. MECHANISTIC STUDIES IN COPD
Pub Date : 2019-05-01 DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a5384
M. Fischer, A. Kirkman-Thomas, P. Mallia, S. Johnston, S. Johnson
{"title":"Elastase Activity as an Indicator of Exacerbation and Disease Severity in COPD","authors":"M. Fischer, A. Kirkman-Thomas, P. Mallia, S. Johnston, S. Johnson","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a5384","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a5384","url":null,"abstract":"","PeriodicalId":448051,"journal":{"name":"C63. MECHANISTIC STUDIES IN COPD","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133489159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
PU.1 Mediates Cigarette Smoke Extract Induced Endothelial Progenitor Cell Dysfunction via Stem Cell Antigen-1 PU.1通过干细胞抗原-1介导香烟烟雾提取物诱导的内皮祖细胞功能障碍
C63. MECHANISTIC STUDIES IN COPD
Pub Date : 2019-05-01 DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a5380
Xue He, L. Luo, Yan Chen
{"title":"PU.1 Mediates Cigarette Smoke Extract Induced Endothelial Progenitor Cell Dysfunction via Stem Cell Antigen-1","authors":"Xue He, L. Luo, Yan Chen","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a5380","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a5380","url":null,"abstract":"","PeriodicalId":448051,"journal":{"name":"C63. MECHANISTIC STUDIES IN COPD","volume":"118 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128167465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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