Pub Date : 2019-05-01DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a7433
J. Speth, L. Penke, Joseph Bazzill, J. Moon, M. Peters-Golden
{"title":"Synthetic Liposome Mimics of Alveolar Macrophage-Derived Vesicles Containing Suppressor of Cytokine Signaling 3: Inhibitors of Lung Tumor Cell Expansion and Potential Therapeutic for Lung Cancer","authors":"J. Speth, L. Penke, Joseph Bazzill, J. Moon, M. Peters-Golden","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a7433","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a7433","url":null,"abstract":"","PeriodicalId":448051,"journal":{"name":"C63. MECHANISTIC STUDIES IN COPD","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115601692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-05-01DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a5385
G. Graves, K. Krotova, N. Khodayari, Regina A Oshins, G. Aslanidi, M. Brantly
{"title":"Neutrophil Elastase Activates Macrophages via Integrin-Src Kinase Pathway","authors":"G. Graves, K. Krotova, N. Khodayari, Regina A Oshins, G. Aslanidi, M. Brantly","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a5385","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a5385","url":null,"abstract":"","PeriodicalId":448051,"journal":{"name":"C63. MECHANISTIC STUDIES IN COPD","volume":"96 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122814144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-05-01DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a5375
M. Sauler, J. Nouws, W. Feng, P. Lee
{"title":"MicroRNA Regulation of Cell Fate in the Pathogenesis of COPD","authors":"M. Sauler, J. Nouws, W. Feng, P. Lee","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a5375","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a5375","url":null,"abstract":"","PeriodicalId":448051,"journal":{"name":"C63. MECHANISTIC STUDIES IN COPD","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130555106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-05-01DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a5369
William Z. Zhang, C. Oromendia, Sarah Ann Kikkers, Kihwan Kim, W. O’Neal, C. Freeman, S. Christenson, S. Peters, J. Wells, C. Doerschuk, N. Putcha, P. Woodruff, C. Cooper, A. Comellas, G. Criner, R. Paine, N. Hansel, M. Han, J. Curtis, R. Kaner, K. Ballman, F. Martinez, S. Cloonan, Spiromics
{"title":"Extracellular Bronchoalveolar Lavage Fluid Ferritin and Risk for Exacerbation in COPD: An Analysis from the Subpopulations and Intermediate Outcome Measures in COPD Study (SPIROMICS)","authors":"William Z. Zhang, C. Oromendia, Sarah Ann Kikkers, Kihwan Kim, W. O’Neal, C. Freeman, S. Christenson, S. Peters, J. Wells, C. Doerschuk, N. Putcha, P. Woodruff, C. Cooper, A. Comellas, G. Criner, R. Paine, N. Hansel, M. Han, J. Curtis, R. Kaner, K. Ballman, F. Martinez, S. Cloonan, Spiromics","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a5369","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a5369","url":null,"abstract":"","PeriodicalId":448051,"journal":{"name":"C63. MECHANISTIC STUDIES IN COPD","volume":"72 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132646668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-05-01DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a5387
S. Lea, L. Hodgson, T. Southworth, F. Facchinetti, G. Villetti, M. Civelli, D. Singh
{"title":"The Effects of PDE4 Inhibitors Roflumilast and CHF6001 on Cytokine Production from COPD BAL Lymphocytes","authors":"S. Lea, L. Hodgson, T. Southworth, F. Facchinetti, G. Villetti, M. Civelli, D. Singh","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a5387","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a5387","url":null,"abstract":"","PeriodicalId":448051,"journal":{"name":"C63. MECHANISTIC STUDIES IN COPD","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131230448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-05-01DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a7430
K. Schiffer, M. Rice, C. Oromendia, William Z. Zhang, S. Peters, P. Woodruff, C. Cooper, R. Bowler, A. Comellas, G. Criner, R. Paine, N. Hansel, M. Han, R. Barr, J. Krishnan, M. Dransfield, J. Curtis, K. Ballman, F. Martinez, K. Nakahira, S. Cloonan, M. E. Choi, A. Choi, Spiromics
{"title":"Association of Circulating Cell-Free Mitochondrial DNA to Outcomes in COPD in the SPIROMICS Cohort","authors":"K. Schiffer, M. Rice, C. Oromendia, William Z. Zhang, S. Peters, P. Woodruff, C. Cooper, R. Bowler, A. Comellas, G. Criner, R. Paine, N. Hansel, M. Han, R. Barr, J. Krishnan, M. Dransfield, J. Curtis, K. Ballman, F. Martinez, K. Nakahira, S. Cloonan, M. E. Choi, A. Choi, Spiromics","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a7430","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a7430","url":null,"abstract":"","PeriodicalId":448051,"journal":{"name":"C63. MECHANISTIC STUDIES IN COPD","volume":"143 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123599730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-05-01DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a5372
L. Ni
{"title":"Role of Human SP-D Genetic Variants in the Pathogenesis of Chronic Lung Injury","authors":"L. Ni","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a5372","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a5372","url":null,"abstract":"","PeriodicalId":448051,"journal":{"name":"C63. MECHANISTIC STUDIES IN COPD","volume":"77 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123795338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-05-01DOI: 10.1164/AJRCCM-CONFERENCE.2019.199.1_MEETINGABSTRACTS.A5371
S. D. Pouwels, F. Klont, M. Kwiatkowski, J. Charbonnier, E. V. Rikxoort, R. Bowler, R. Bischoff, N. T. Hacken
{"title":"Serum Levels of the COPD-Biomarker sRAGE Strongly Correlate with Specific Phenotypes and the Progression of Emphysema","authors":"S. D. Pouwels, F. Klont, M. Kwiatkowski, J. Charbonnier, E. V. Rikxoort, R. Bowler, R. Bischoff, N. T. Hacken","doi":"10.1164/AJRCCM-CONFERENCE.2019.199.1_MEETINGABSTRACTS.A5371","DOIUrl":"https://doi.org/10.1164/AJRCCM-CONFERENCE.2019.199.1_MEETINGABSTRACTS.A5371","url":null,"abstract":"","PeriodicalId":448051,"journal":{"name":"C63. MECHANISTIC STUDIES IN COPD","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114211428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-05-01DOI: 10.1164/AJRCCM-CONFERENCE.2019.199.1_MEETINGABSTRACTS.A5376
E. Roscioli, M. Poh, A. Kicic, S. Lester, Phan T Nguyen, H. Jersmann, P. Reynolds, S. Hodge
{"title":"Nontypeable Haemophilus Influenzae (NTHi) Exploits Disease-Related Defects in Xenophagy to Persist and Traffic Within the Epithelial Compartment During COPD","authors":"E. Roscioli, M. Poh, A. Kicic, S. Lester, Phan T Nguyen, H. Jersmann, P. Reynolds, S. Hodge","doi":"10.1164/AJRCCM-CONFERENCE.2019.199.1_MEETINGABSTRACTS.A5376","DOIUrl":"https://doi.org/10.1164/AJRCCM-CONFERENCE.2019.199.1_MEETINGABSTRACTS.A5376","url":null,"abstract":"","PeriodicalId":448051,"journal":{"name":"C63. MECHANISTIC STUDIES IN COPD","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129453501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-05-01DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a7431
L. Benninger, J. Lee, K. Krotova, J. West, J. Lascano, M. Brantly
{"title":"Nicotine Plays a Key Role on Inflammation Driven by Monocyte-Derived-Macrophages of Subjects with Alpha-1 Antitrypsin Deficiency","authors":"L. Benninger, J. Lee, K. Krotova, J. West, J. Lascano, M. Brantly","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a7431","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a7431","url":null,"abstract":"","PeriodicalId":448051,"journal":{"name":"C63. MECHANISTIC STUDIES IN COPD","volume":"124 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125118512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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