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Childhood myopia and the coronavirus disease 2019 pandemic: Lessons for future pandemics. 儿童近视与 2019 年冠状病毒疾病大流行:对未来大流行的启示。
IF 1 Q4 OPHTHALMOLOGY Pub Date : 2024-05-27 eCollection Date: 2024-04-01 DOI: 10.4103/tjo.TJO-D-24-00010
Jonathan T W Au Eong, Jarryl H J Tsai, Niall J Crosby, Kah-Guan Au Eong
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引用次数: 0
Myopia intervention and ultraviolet radiation related eye diseases: A narrative literature review. 近视干预与紫外线辐射相关眼病:叙事性文献综述。
IF 1 Q4 OPHTHALMOLOGY Pub Date : 2024-05-27 eCollection Date: 2024-04-01 DOI: 10.4103/tjo.TJO-D-24-00011
Shanel Sharma, Loreto Rose, Angela Schulz, Daya P Sharma, Alina Zeldovich, Cristena Azzi, Ken Nischal

There has been an increased understanding of the protective effect of two or more hours in high lux light on the development and progression of myopia. The aim of myopia management is to reduce the incidence of high myopia and sight-threatening myopic complications. Equally important are the sight-threatening complications of ultraviolet radiation (UVR) on the eye and adnexal structures. This review will analyze the literature for both these epidemics to help guide public health policy. Whilst increasing childhood high lux light exposure is important, consideration of a holistic eye health policy should ensure that UV eye diseases are also prevented. The advent of ultraviolet (UV) fluorescence photography has increased our understanding that significant UV eye damage occurs in childhood, with 81% of children aged 12-15 years having signs of UV eye damage. Hence, the need to reduce myopia and protect from UV-related eye diseases needs simultaneous consideration. Advocating for eye protection is important, particularly as the natural squint reflex is disabled with dark sunglasses lenses. The pathways UV reaches the eye need to be considered and addressed to ensure that sunglasses offer optimum UV eye protection. The design of protective sunglasses that simultaneously allow high lux light exposure and protect from UVR is critical in combating both these epidemics.

人们越来越多地认识到,在高勒克斯光下两小时或更长时间对近视的发展和恶化具有保护作用。近视管理的目的是减少高度近视和危及视力的近视并发症的发生率。同样重要的是,紫外线辐射(UVR)对眼睛和附件结构造成的危及视力的并发症。本综述将分析有关这两种流行病的文献,以帮助指导公共卫生政策。虽然增加儿童的高勒克斯光暴露量很重要,但考虑全面的眼健康政策也应确保紫外线眼病得到预防。紫外线(UV)荧光摄影的出现使我们进一步认识到,紫外线对眼睛的严重伤害发生在儿童时期,81%的 12-15 岁儿童都有紫外线对眼睛伤害的迹象。因此,需要同时考虑降低近视度数和预防紫外线相关眼病。倡导保护眼睛非常重要,尤其是在佩戴深色太阳镜镜片后,自然斜视反射会失效。需要考虑和解决紫外线到达眼睛的途径,以确保太阳镜提供最佳的紫外线眼睛保护。设计同时允许高勒克斯光照射和防止紫外线辐射的保护性太阳镜,对于防治这两种流行病至关重要。
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引用次数: 0
Seeing the future: Ophthalmology gets "eye-tech" savvy with Internet of Medical Thing. 预见未来:眼科借助医疗物联网掌握 "眼科技术"。
IF 1 Q4 OPHTHALMOLOGY Pub Date : 2024-04-26 eCollection Date: 2024-07-01 DOI: 10.4103/tjo.TJO-D-24-00014
Dhruval Ashok Khurana
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引用次数: 0
Corneal transplantation surgery: Where we are and where are we going? 角膜移植手术:我们的现状和未来?
IF 1.1 Q4 OPHTHALMOLOGY Pub Date : 2024-03-15 eCollection Date: 2024-01-01 DOI: 10.4103/tjo.TJO-D-24-00009
Jorge L Alio
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引用次数: 0
Systemic treatment and surgical intervention in inflammatory Terrien disease. 炎症性特里恩病的系统治疗和手术干预。
IF 1.1 Q4 OPHTHALMOLOGY Pub Date : 2024-03-15 eCollection Date: 2024-01-01 DOI: 10.4103/tjo.TJO-D-23-00176
Francisco Arnalich-Montiel

This case report presents a unique instance of a 55-year-old male patient exhibiting features of both Terrien marginal degeneration (TMD) and Fuchs' superficial marginal keratitis. Characterized by peripheral corneal thinning vascularization, and a pseudopterygium, the patient experienced recurrent photophobia, redness, and tearing over 15 years. This case challenges the traditional distinction between TMD and Fuchs' superficial marginal keratitis, suggesting a potential common underlying disorder. Mycophenolate mofetil provided a partial response, while pseudopterygium removal led to sustained remission, emphasizing its therapeutic significance. This case highlights the first documented use of mycophenolate in TMD and supports the notion of shared vasculitic origins between TMD and Fuchs' keratitis, raising intriguing questions about targeted therapeutic interventions.

本病例报告介绍了一名 55 岁男性患者的独特病例,该患者同时具有特里恩角膜缘变性(Terrien marginal degeneration,TMD)和福氏浅缘角膜炎的特征。患者的特征是角膜周边血管变细和假性翼状胬肉,15 年来反复出现畏光、发红和流泪症状。该病例对 TMD 和 Fuchs 表浅边缘角膜炎之间的传统区别提出了质疑,提示两者可能存在共同的潜在疾病。霉酚酸酯可缓解部分症状,而切除假性翼状胬肉则可使症状持续缓解,这突出了假性翼状胬肉的治疗意义。该病例是首次在 TMD 中使用霉酚酸酯的记录,支持了 TMD 和 Fuchs 角膜炎之间有共同的血管病变起源的观点,提出了有关针对性治疗干预的有趣问题。
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引用次数: 0
Pre-Descemet's endothelial keratoplasty with glued intraocular lens implantation with pinhole pupilloplasty in a case of ocular comorbidity in achromatopsia. 在一例无色素性视网膜病变患者的眼部合并症中,采用前去角皮内皮角膜移植术和针孔瞳孔成形术植入胶合型人工晶体。
IF 1.1 Q4 OPHTHALMOLOGY Pub Date : 2024-03-15 eCollection Date: 2024-01-01 DOI: 10.4103/tjo.TJO-D-23-00172
Dhivya Ashok Kumar, Amar Agarwal, Swetha Ravichandran

Ocular comorbidities can happen as congenital defective gene associations. We present a 37-year-old female patient who was mentally challenged and had coexisting achromatopsia gene abnormality on genetic analysis. She was operated in childhood for congenital cataract, and posterior chamber intraocular lens (IOL) was implanted at 10 years of age elsewhere. The patient presented 27 years later with luxated IOL with endothelial decompensation. There was a coexisting steep and thin cornea noted on corneal topography. She was managed with pre-Descemet's endothelial keratoplasty with transpositioning of posterior chamber IOL to glued IOL with single-pass four-throw pupilloplasty. Postoperatively, the cornea was clear with centered glued IOL. The lesser postanesthetic challenges and faster rehabilitation are obtained in combination procedures with reduced complications in such rare scenarios.

眼部合并症可能与先天性缺陷基因有关。我们为您介绍一位 37 岁的女性患者,她有智力障碍,并且在基因分析中同时存在色弱基因异常。她在童年时因先天性白内障接受了手术,10 岁时在其他地方植入了后房型人工晶体(IOL)。27 年后,患者因内皮失代偿而出现人工晶体脱落。角膜地形图显示,患者的角膜陡薄。她接受了前戴斯麦内皮角膜移植术,将后房型人工晶体移位为粘连型人工晶体,并进行了单程四抛瞳孔成形术。术后,居中的胶合人工晶体使角膜变得清晰。在这种罕见的情况下,联合手术的麻醉后挑战较小,康复较快,并减少了并发症。
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引用次数: 0
Resurgence of orbital mucormycosis during COVID-19 pandemic: Study from a tertiary care center in Eastern India COVID-19大流行期间眼眶粘液瘤病复发:印度东部一家三级医疗中心的研究
IF 1.1 Q4 OPHTHALMOLOGY Pub Date : 2024-01-09 DOI: 10.4103/tjo.tjo-d-23-00110
Soumen Chakraborty, Satish Reddy Satty, Badal Kumar Sahu, Soumya Ray
A sudden surge of Mucormycosis cases during the second wave of Covid 19 was observed in certain parts of India. The reasons for this upsurge remain unknown. However its impact on the overall healthcare system was quite overwhelming. In this context this study was decided to estimate and assess the spectrum of orbital involvement in patients with Mucormycosis, to find its association with coexisting disease entities if any, and at the same time evaluate the therapeutic response to established treatment regimens. This descriptive longitudinal study was conducted over a period of six months. Patients presenting with symptoms of Mucormycosis were jointly evaluated by a multi speciality team. After confirmation of diagnosis, patients were treated with intravenous Amphotericin B, surgical debridement of affected sinuses and orbital exenteration when indicated. They were followed up for three months after discharge. Forty-three patients were enrolled in this study. Thirty-seven (86.04%) were COVID positive. All of them had history of steroid exposure during COVID treatment. Ninety five percent of study participants had diabetes mellitus. Twenty-seven (62.79%) patients had orbital involvement. Most common clinical presentation was peri-orbital or facial pain and edema. Besides medical treatment, thirty-nine patients (90.69%) required sinus debridement and nine patients (20.9%) required orbital exenteration. Thirteen patients (30.23%) expired during the follow up period. With treatment disease regressed in twenty patients (46.51%). Diabetes and use of steroids to prevent anticipated cytokine storm may be the inciting factors for Orbital Mucormycosis in COVID patients. Early diagnosis, treatment and control of risk factors are keys for recovery and survival..
在 Covid 19 第二波期间,印度某些地区的粘孢子菌病例突然激增。病例激增的原因尚不清楚。然而,它对整个医疗保健系统的影响是巨大的。在这种情况下,我们决定开展这项研究,以估计和评估粘孢子菌病患者眼眶受累的范围,找出其与并存疾病实体(如果有的话)的关联,同时评估对既定治疗方案的治疗反应。 这项描述性纵向研究为期六个月。出现黏液疽症状的患者由一个多专业团队共同评估。确诊后,患者接受了两性霉素 B 静脉注射、受影响鼻窦的手术清创以及必要时的眼眶外扩治疗。出院后对患者进行了为期三个月的随访。 本研究共纳入 43 名患者。37例(86.04%)为COVID阳性。所有患者在接受 COVID 治疗期间均有类固醇暴露史。95%的研究参与者患有糖尿病。27名患者(62.79%)眼眶受累。最常见的临床表现是眶周或面部疼痛和水肿。除药物治疗外,39 名患者(90.69%)需要进行鼻窦清创术,9 名患者(20.9%)需要进行眶外扩张术。有 13 名患者(30.23%)在随访期间去世。经过治疗,20 名患者(46.51%)的病情有所缓解。 糖尿病和使用类固醇来预防预期的细胞因子风暴可能是COVID患者眶内黏液瘤病的诱发因素。早期诊断、治疗和控制风险因素是康复和存活的关键。
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引用次数: 0
Cancer-associated retinopathy as an initial presentation of gynecologic small-cell carcinoma 癌症相关性视网膜病变是妇科小细胞癌的最初表现形式
IF 1.1 Q4 OPHTHALMOLOGY Pub Date : 2024-01-09 DOI: 10.4103/tjo.tjo-d-23-00100
Hwa-Shin Fang, Chang-Sue Yang, Cheng-Kuo Cheng, Yuangwei Wang
A 56-year-old female presented with bilateral progressive blurred vision over 1 month. She has no known malignancy before her initial visit to our ophthalmologic clinic. Her best-corrected visual acuity decreased to hand motion from 30 cm in both eyes. Optical coherence tomography exhibited parafoveal thinning of outer retinal layers bilaterally. Fluorescein angiography and indocyanine green angiography disclosed hypofluorescent spots in late phase in both eyes. The suspicion of cancer-associated retinopathy (CAR) prompted us to investigate and refer for further systemic disease including occult malignancy. The patient was diagnosed with small-cell carcinoma of the endometrium or cervix, which is an extremely rare and aggressive neuroendocrine tumor. The patient was treated with oral prednisone with improved visual acuity. The patient expired from sepsis 2 months after her initial visit to our ophthalmologic clinic. In selected cases, CAR may present before the diagnosis of primary cancer. It is essential to recognize its ophthalmic manifestation for early discovery of primary malignancy.
一名 56 岁的女性在 1 个月内出现双侧进行性视力模糊。在初次来我院眼科门诊就诊之前,她没有任何已知的恶性肿瘤。她双眼的最佳矫正视力下降到 30 厘米以外的手部运动。光学相干断层扫描显示,双侧视网膜外层旁变薄。荧光素血管造影和吲哚菁绿血管造影显示,双眼晚期均出现低荧光斑。癌症相关视网膜病变(CAR)的怀疑促使我们进一步调查和转诊全身性疾病,包括隐匿性恶性肿瘤。患者被诊断为子宫内膜或宫颈小细胞癌,这是一种极其罕见的侵袭性神经内分泌肿瘤。患者接受了口服泼尼松治疗,视力有所改善。患者在首次到我院眼科就诊 2 个月后因败血症去世。在某些情况下,CAR 可能会在诊断出原发性癌症之前出现。识别其眼部表现对于早期发现原发性恶性肿瘤至关重要。
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引用次数: 0
An update on the ocular manifestations of dengue 登革热眼部表现的最新进展
IF 1.1 Q4 OPHTHALMOLOGY Pub Date : 2024-01-09 DOI: 10.4103/tjo.tjo-d-23-00106
Christina Wang, Arturo Castillo, Federico Cortes-Bejarano, Eduardo Lopez, Eduardo Cunha de Souza, Lihteh Wu
Dengue is the most common arboviral disease. It is typically spread by the bite of an infected female Aedes aegypti or Aedes albopictus mosquitoes. Dengue is endemic in subtropical and tropical regions, but its geographic reach keeps expanding. Ophthalmic manifestations of dengue are common and may present with a wide spectrum of ophthalmic findings. These may range from conjunctival petechiae, retinal hemorrhage, retinal vasculitis to panophthalmitis. Some of these may be vision threatening and may require urgent ophthalmic evaluation. The precise pathophysiologic mechanisms involved in dengue infection involve a complex interplay between host immune responses, virus, and host genes. There is no specific treatment for ocular dengue. Therefore, treatment is supportive. Despite the lack of proven efficacy, corticosteroids have been used in vision-threatening dengue-related ocular complications. Dengue must be considered in endemic areas, and a careful travel history needs to be elicited in nonendemic areas.
登革热是最常见的虫媒病毒疾病。它通常通过受感染的雌性埃及伊蚊或白纹伊蚊叮咬传播。登革热在亚热带和热带地区流行,但其传播范围在不断扩大。登革热的眼部表现很常见,可出现多种眼部症状。这些症状包括结膜瘀斑、视网膜出血、视网膜血管炎和全眼炎。其中有些可能会危及视力,需要进行紧急眼科评估。登革热感染的确切病理生理机制涉及宿主免疫反应、病毒和宿主基因之间复杂的相互作用。眼部登革热没有特效治疗方法。因此,治疗是辅助性的。尽管缺乏经证实的疗效,但皮质类固醇已被用于治疗威胁视力的登革热相关眼部并发症。在登革热流行地区必须考虑登革热,而在非流行地区则需要仔细询问旅行史。
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引用次数: 0
Comparative evaluation of “closed posterior levator advancement” in simple congenital and aponeurotic ptosis 单纯性先天性上睑下垂和肌腱膜性上睑下垂的 "闭合性后上睑提肌腱膜前移术 "比较评估
IF 1.1 Q4 OPHTHALMOLOGY Pub Date : 2024-01-05 DOI: 10.4103/tjo.tjo-d-23-00081
R. Goel, Sonam Singh, Shalin Shah, S. Khanam, Priyanka Golhait, Tanvi Gaonker
The purpose of this study was to compare the outcomes of “closed posterior levator advancement” (CPLA) in acquired aponeurotic and simple congenital ptosis with good levator function (LF). A prospective interventional study was conducted on 20 adult patients, 10 simple congenital ptosis, and 10 acquired aponeurotic ptosis with LF ≥8 mm. Complicated, posttraumatic, neurogenic ptosis and previous lid surgery were excluded. A detailed history and assessment of visual acuity, upper eyelid margin reflex distance (MRD1), margin-crease distance, LF, Bell’s phenomenon, ocular surface disease index (OSDI), and phenylephrine test were undertaken. CPLA was performed in the 20 eyes and were followed up for 3 months. The ages of the study participants ranged from 18 to 64 years, and the male: female ratio was 11:9. There were nine aponeurotic and one congenital severe ptosis, the remaining 10 being mild–moderate ptosis. The etiologies in the aponeurotic group were involutional (2), contact lens wear (1), allergic conjunctivitis (3), and idiopathic in four eyes. The success rates were 90% in both groups. The amount of ptosis correction showed a positive relation with LF (r s = 0.6, P = 0.004) and phenylephrine test (r s = 0.7, P < 0.001). The complications in the aponeurotic group were lagophthalmos (2/10), subjective dry eye (2/10), subconjunctival hemorrhage (1/10), symblepharon (1/10), temporal flare (1/10), and overcorrection (1/10). The congenital group showed only undercorrection (1/10). CPLA is an effective procedure for the treatment of mild–moderate simple congenital and all grades of aponeurotic ptosis with good LF. Response to phenylephrine test serves as a useful guide to the amount of ptosis correction.
本研究旨在比较 "闭合性后上睑提肌腱膜前移术"(CPLA)对上睑提肌功能(LF)良好的后天性上睑下垂和单纯性先天性上睑下垂的治疗效果。 我们对 20 名成年患者进行了前瞻性介入研究,其中 10 名为单纯先天性上睑下垂,10 名为后天性上睑下垂且提上睑肌功能≥8 mm。研究排除了并发症、外伤后、神经源性上睑下垂和曾接受过睑板手术的患者。详细询问了病史,并评估了视力、上睑缘反射距离(MRD1)、睑缘增宽距离、LF、贝尔现象、眼表疾病指数(OSDI)和苯肾上腺素试验。对 20 只眼睛进行了 CPLA 检查,并随访 3 个月。 研究对象的年龄从18岁到64岁不等,男女比例为11:9。其中有 9 只眼球为肌腱膜性上睑下垂,1 只为先天性重度上睑下垂,其余 10 只为轻中度上睑下垂。肌腱膜性上睑下垂组的病因是内卷(2 例)、佩戴隐形眼镜(1 例)、过敏性结膜炎(3 例),另有 4 例为特发性上睑下垂。两组的成功率均为 90%。上睑下垂矫正量与 LF(r s = 0.6,P = 0.004)和苯肾上腺素试验(r s = 0.7,P < 0.001)呈正相关。肌腱组的并发症有眼睑下垂(2/10)、主观干眼症(2/10)、结膜下出血(1/10)、眼睑外翻(1/10)、颞叶外翻(1/10)和过度矫正(1/10)。先天性组仅出现矫正不足(1/10)。 CPLA 是治疗轻度-中度单纯先天性上睑下垂和各种程度的上睑下垂的有效方法,且 LF 良好。对苯肾上腺素试验的反应可作为上睑下垂矫正量的有效指导。
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引用次数: 0
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Taiwan Journal of Ophthalmology
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