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Hidden Risk Factors Overlooked by qSOFA in Emergency Department Sepsis Patients: A Multicenter Retrospective Cohort. 急诊败血症患者qSOFA忽视的潜在危险因素:一项多中心回顾性队列研究。
IF 1.5 Q3 EMERGENCY MEDICINE Pub Date : 2025-11-28 eCollection Date: 2025-01-01 DOI: 10.2147/OAEM.S546101
Saqer Althunayyan

Objective: Despite the numerous studies critiquing the Quick Sequential Organ Failure Assessment (qSOFA) score for sepsis prognosis in the emergency department (ED), there are limited known risk factors that can be missed by qSOFA.

Methods: This is a multicenter retrospective cohort study using ED data from Dr Sulaiman AL-Habib Medical Group Hospitals in Riyadh, Saudi Arabia. We assessed all suspected septic patients who came through the EDs from 1st May 2022 to 30th April 2023 with the qSOFA < 2. Among these patients, we identify those who develop critical outcomes (the requirement for vasopressors/inotropes or mortality) within 72 hours of triage. Additionally, we analyzed the potential risk factors of critical outcomes using a multivariable logistic regression model.

Results: We identified 1011 patients who presented with suspected sepsis and qSOFA < 2. Among them, 70 patients developed critical outcomes within 72 hours. In the multivariable logistic regression model, the potential risk factors for critical outcomes were age ≥65 years (adjusted OR, 3.87 [1.25, 14.9]), lactate ≥ 2.5 mmol/L with adjusted OR 2.04 [1.16, 3.54], and shock index >1 with adjusted OR 3.27 [1.13, 10.3]. There are no specific comorbidities that were independently associated with the critical outcomes.

Conclusion: The study identified potential risk factors for sepsis outcomes that qSOFA overlooks. Integration of risk factors (lactate, shock index, age) with qSOFA could enhance early sepsis recognition and improve patient outcomes. We recommend further studies to validate these risk factors.

目的:尽管有大量研究批评急诊科(ED)败血症预后的快速顺序器官衰竭评估(qSOFA)评分,但qSOFA可以遗漏的已知危险因素有限。方法:这是一项多中心回顾性队列研究,使用来自沙特阿拉伯利雅得的Dr Sulaiman AL-Habib医疗集团医院的ED数据。我们评估了2022年5月1日至2023年4月30日期间通过急诊科就诊的所有qSOFA < 2的疑似脓毒症患者。在这些患者中,我们确定了那些在分诊72小时内出现关键结果(血管加压药/肌力药物或死亡率的要求)的患者。此外,我们使用多变量逻辑回归模型分析了关键结果的潜在危险因素。结果:我们确定了1011例疑似脓毒症且qSOFA < 2的患者。其中70例患者在72小时内出现危重结局。在多变量logistic回归模型中,关键结局的潜在危险因素为年龄≥65岁(调整OR为3.87[1.25,14.9])、乳酸≥2.5 mmol/L(调整OR为2.04[1.16,3.54])和休克指数>1(调整OR为3.27[1.13,10.3])。没有特定的合并症与关键结果独立相关。结论:该研究确定了qSOFA忽略的脓毒症结局的潜在危险因素。将危险因素(乳酸、休克指数、年龄)与qSOFA结合,可提高脓毒症的早期识别,改善患者预后。我们建议进一步研究以证实这些危险因素。
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引用次数: 0
Improving Emergency Medicine Residents' Comfort in Responding to Mass Casualty Incidents: A Cost-Effective Exercise Utilizing Real-Time Feedback. 提高急诊医师在应对大规模伤亡事件中的舒适度:利用实时反馈的成本效益练习。
IF 1.5 Q3 EMERGENCY MEDICINE Pub Date : 2025-11-27 eCollection Date: 2025-01-01 DOI: 10.2147/OAEM.S523946
Sara L Wattenbarger

Background: Mass casualty incidents present significant challenges to healthcare systems, necessitating effective triage and response from emergency personnel. Unfortunately, emergency medicine residents have reported discomfort with disaster preparation and lack of confidence at the prospect of responding to large-scale mass casualty incidents. Mass casualty preparation exercises are often costly, time-consuming to plan, and resource prohibitive, complicating disaster training initiatives for emergency medicine residency programs. We implemented and evaluated a novel training exercise geared toward improving resident comfort levels in utilizing the START (Simple Triage and Rapid Treatment) and JumpSTART triage algorithms that incorporated easily acquired materials and required limited faculty time commitment.

Methods: We staged two small-scale mass casualty exercises in May 2023 and December 2024 utilizing moulaged dolls and props designed to mimic a disaster scene. Dolls were equipped with QR codes linked to short vignettes including vital signs and relevant clinical information. Residents were instructed to assign a triage designation based on the information provided and input their response into Google Forms. Once submitted, participants received immediate feedback regarding the accuracy of their response, along with an explanation of why they were or were not correct.

Results: A total of thirteen residents for the first, and twelve residents for the second exercise implementation participated, completing pre- and post-intervention surveys to evaluate their comfort with mass casualty scenarios using the START triage system. Results indicated a 66% increase (first implementation) and 55% increase (second implementation) in the likelihood of residents feeling "mostly" or "very" comfortable post-exercise. Participants rated the teaching quality and instructional tools as "excellent".

Conclusion: Resident confidence in responding to mass casualty incidents improved post-exercise via the use of a cost-effective and easily replicable mass casualty triage training model, circumventing the need for costly simulation equipment and extensive faculty involvement.

背景:大规模伤亡事件对医疗保健系统提出了重大挑战,需要应急人员进行有效的分类和响应。不幸的是,急诊医师报告说,他们对灾难准备感到不安,对应对大规模伤亡事件的前景缺乏信心。大规模伤亡准备演习通常是昂贵的,耗时的计划,和资源禁止,复杂的灾害培训倡议急救医学住院医师计划。我们实施并评估了一项新的培训活动,旨在提高住院医生在使用START(简单分诊和快速治疗)和JumpSTART分诊算法方面的舒适度,这些算法包含了容易获得的材料,并且需要有限的教师时间投入。方法:我们在2023年5月和2024年12月进行了两次小规模的大规模伤亡演习,利用模拟灾难现场的模塑娃娃和道具。娃娃身上装有二维码,这些二维码与包括生命体征和相关临床信息在内的短片段相关联。居民被指示根据提供的信息分配一个分类名称,并将他们的回答输入谷歌表格。一旦提交,参与者立即收到关于他们的回答的准确性的反馈,以及为什么他们是正确的或不正确的解释。结果:共有13名居民参加了第一次演习,12名居民参加了第二次演习,他们完成了干预前和干预后的调查,使用START分诊系统评估他们对大规模伤亡情景的舒适度。结果表明,居民在运动后感觉“大部分”或“非常”舒适的可能性增加了66%(第一次实施)和55%(第二次实施)。学员对教学质量和教学工具的评价为“优秀”。结论:通过使用具有成本效益且易于复制的大规模伤亡分类培训模型,避免了昂贵的模拟设备和广泛的教师参与,居民对大规模伤亡事件的反应信心得到了提高。
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引用次数: 0
Conservative Management of Perforated Duodenal Diverticulum: A Case Report and Narrative Review. 十二指肠憩室穿孔的保守治疗:1例报告及叙述回顾。
IF 1.5 Q3 EMERGENCY MEDICINE Pub Date : 2025-11-14 eCollection Date: 2025-01-01 DOI: 10.2147/OAEM.S547882
Tagleb S Mazahreh, Mohammed W Afaneh, Anas Husein

Duodenal diverticular disease is a common finding in the general population and most individuals, in fact, remain asymptomatic. However, duodenal diverticular perforation is an occasional unfortunate endpoint that carries significant morbidity, and mortality rates and requires a particular attention and a wise judgement whether to liberally interfere surgically or to stay more conservative.In this writing, we describe a case of a 45-year-old male with a perforated duodenal diverticulum that presented in a stable general condition and was successfully managed conservatively, sparing the patient a particularly morbid surgical intervention. Perforated duodenal diverticula, though rare, can be managed conservatively in stable patients without signs of sepsis or generalized peritonitis. Conservative treatment, including intravenous antibiotics, bowel rest, and nasogastric suction, can be effective and avoid the morbidity associated with surgery. In our case, conservative management led to significant improvement, underscoring the importance of individualized treatment plans and close monitoring to decide on the necessity of surgical intervention.Conservative management of perforated duodenal diverticula should be considered in selected patients who fulfill the general settled criteria. Nevertheless, an individualized approach is recommended and escalating up the invasiveness of interventions may seem vital at any time during treatment.

十二指肠憩室疾病在一般人群中是一种常见的发现,事实上,大多数人仍然没有症状。然而,十二指肠憩室穿孔是一个偶然的不幸的终末,具有显著的发病率和死亡率,需要特别注意和明智的判断是自由干预手术还是保持更保守。在这篇文章中,我们描述了一例45岁男性十二指肠憩室穿孔的病例,该病例一般情况稳定,并成功地进行了保守治疗,使患者免于特别病态的手术干预。穿孔的十二指肠憩室,虽然罕见,可以保守处理稳定的病人没有败血症或全身性腹膜炎的迹象。保守治疗,包括静脉注射抗生素、肠道休息和鼻胃吸引,可以有效地避免手术相关的发病率。在我们的病例中,保守治疗导致了显著的改善,强调了个体化治疗计划和密切监测的重要性,以决定手术干预的必要性。选择符合一般确定标准的患者,应考虑保守治疗十二指肠憩室穿孔。尽管如此,建议采用个性化的方法,并且在治疗期间的任何时候,提高干预措施的侵入性似乎都是至关重要的。
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引用次数: 0
The Use of TRAUMAGEL® for Hemorrhage Control in a Complex Head Laceration: A Case Report. 创伤治疗在复杂头部撕裂伤出血控制中的应用:1例报告。
IF 1.5 Q3 EMERGENCY MEDICINE Pub Date : 2025-11-11 eCollection Date: 2025-01-01 DOI: 10.2147/OAEM.S546914
David Jay Kleiman, Tyler Nicholas Carruth, James Infanzon, Marvin E Nix, Brian J Goldstone

Prehospital geriatric falls account for approximately a fifth of emergency medical services (EMS) call volumes nationwide, with a significant proportion involving head injuries and lacerations. Managing these injuries and associated hemorrhage requires substantial resource utilization, including personnel, time, and supplies. Complicating care is that many geriatric patients are maintained on long-term oral anticoagulant or antiplatelet therapy, making hemorrhage control more difficult. Failure to achieve adequate hemostasis in the field can delay critical assessments and further intervention. This case report describes the prehospital use of a novel hemostatic gel (Traumagel) in managing a complex head laceration. Traumagel achieves rapid and reliable hemostasis in complex wounds that may not be amenable to other hemostatic techniques. Deploying this gel alone or in combination with traditional methods enables emergency medical providers in the field to shift their focus to advanced patient care, allowing for earlier transport to definitive care. In this case, an elderly patient on chronic antiplatelet therapy (Clopidogrel) sustained a complex, open scalp laceration following a ground-level fall. EMS controlled a mixed venous-arterial hemorrhage unresponsive to direct pressure and traditional hemostatic interventions using Traumagel. Effective field hemostasis helped avoid trauma activation and potential operative intervention. The wound was successfully repaired in the emergency department without complication. This report underscores the importance of EMS providers integrating traditional techniques with emerging hemostatic technologies to optimize outcomes in moderate to severe trauma-related hemorrhage.

院前老年人跌倒约占全国紧急医疗服务(EMS)呼叫量的五分之一,其中很大一部分涉及头部受伤和撕裂伤。处理这些损伤和相关出血需要大量的资源利用,包括人员、时间和物资。复杂的护理是,许多老年患者维持长期口服抗凝或抗血小板治疗,使出血控制更加困难。未能在现场实现充分止血可能会延迟关键评估和进一步干预。本病例报告描述院前使用一种新型止血凝胶(创伤凝胶)在管理复杂的头部撕裂伤。对于复杂的伤口,创伤止血仪可以实现快速可靠的止血,而其他止血技术可能无法做到。单独使用这种凝胶或与传统方法结合使用,可以使现场的急救医疗提供者将重点转移到高级患者护理上,从而可以更早地进行最终护理。在本病例中,一位接受慢性抗血小板治疗(氯吡格雷)的老年患者在地面坠落后出现复杂的开放性头皮撕裂伤。EMS控制了对直接加压和传统止血干预无反应的静脉-动脉混合性出血。有效的现场止血有助于避免创伤激活和潜在的手术干预。伤口在急诊科成功修复,无并发症。本报告强调了EMS提供者将传统技术与新兴止血技术相结合的重要性,以优化中重度创伤性出血的预后。
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引用次数: 0
Analysis of Global Research Trends of Trauma-Related Arrhythmias. 外伤性心律失常全球研究趋势分析。
IF 1.5 Q3 EMERGENCY MEDICINE Pub Date : 2025-11-07 eCollection Date: 2025-01-01 DOI: 10.2147/OAEM.S542267
Jiaxing Zhang, Xi Feng, Sai Hu

Background: Arrhythmia is a common complication among trauma patients and is frequently encountered in clinical practice. It is highly prevalent in this population and is associated with an elevated risk of adverse outcomes, including myocardial infarction, cerebrovascular events, and prolonged hospitalization.

Methods: We conducted a bibliometric analysis using CiteSpace and VOSviewer to perform both qualitative and quantitative assessments of the literature, including publication volume, contributing countries and institutions, leading authors, and keyword co-occurrence patterns.

Results: A comprehensive search of the Web of Science Core Collection database was performed for publications on trauma and arrhythmia from January 2014 to December 2024, yielding 5,840 relevant articles. The annual number of publications increased steadily, peaking in 2021 (764 articles), followed by a slight decline in 2022 (756 articles). The United States was the most productive country, accounting for 2,056 articles (35.2%). The Mayo Clinic emerged as the leading institution (107 articles), and Dr. Shinsuke Miyazaki was the most prolific author (34 articles, 0.58%). Frequently occurring keywords included atrial fibrillation, spinal cord injury, post-traumatic stress disorder, blunt chest trauma, traumatic brain injury, hip fracture, head trauma, chest trauma, pelvic fracture, and spinal cord injury. Among trauma types, spinal cord injury, traumatic brain injury, chest trauma, pelvic fracture, and post-traumatic stress disorder were most strongly associated with arrhythmia development, with atrial fibrillation being the predominant arrhythmic subtype.

Conclusion: This study represents the first bibliometric analysis to map the global research landscape of trauma-related arrhythmia. It delineates current research trends, identifies key contributors and thematic foci, and offers novel insights to guide future investigations into the mechanisms, prevention, and management of trauma-induced arrhythmias, while also forecasting emerging research hotspots.

背景:心律失常是创伤患者常见的并发症,在临床实践中较为常见。它在这一人群中非常普遍,并与不良后果的风险升高相关,包括心肌梗死、脑血管事件和住院时间延长。方法:利用CiteSpace和VOSviewer进行文献计量学分析,对文献进行定性和定量评估,包括出版数量、贡献国家和机构、主要作者和关键词共现模式。结果:全面检索Web of Science Core Collection数据库2014年1月至2024年12月关于创伤和心律失常的出版物,获得相关文章5840篇。年发表数量稳步增长,在2021年达到峰值(764篇),随后在2022年略有下降(756篇)。美国是产量最高的国家,共生产2056件(35.2%)。梅奥诊所(Mayo Clinic)位居第一(107篇),宫崎骏博士是最多产的作者(34篇,0.58%)。频繁出现的关键词包括心房颤动、脊髓损伤、创伤后应激障碍、钝性胸外伤、创伤性脑损伤、髋部骨折、头部外伤、胸部外伤、骨盆骨折和脊髓损伤。在创伤类型中,脊髓损伤、外伤性脑损伤、胸部创伤、骨盆骨折和创伤后应激障碍与心律失常的发展最密切相关,心房颤动是主要的心律失常亚型。结论:本研究首次通过文献计量学分析绘制了创伤性心律失常的全球研究图景。它描述了当前的研究趋势,确定了关键贡献者和主题焦点,并提供了新的见解,以指导未来对创伤性心律失常的机制,预防和管理的调查,同时也预测了新兴的研究热点。
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引用次数: 0
Evaluating Quality of Care in Emergency Departments: Perspectives of Patients' and Health Professionals in Saudi Arabia. 急诊护理质量评估:沙特阿拉伯患者和卫生专业人员的观点
IF 1.5 Q3 EMERGENCY MEDICINE Pub Date : 2025-10-26 eCollection Date: 2025-01-01 DOI: 10.2147/OAEM.S547582
Mashael A Hobani, Abdullatif A Almarashi, Ali H Dammas, Lina H Khusheim, Ghassan A Murshid, Turki G Alahmadi, Waleed M Kattan, Khalid A Alasmari

Background: The emergency department (ED) plays a vital role in providing life-saving services in hospitals worldwide. In Jeddah province, Saudi Arabia, the Ministry of Health introduced the "Door to Disposition" key performance indicator (KPI) to enhance ED service quality by addressing overcrowding, limited bed capacity, delays in patient transfer, and complex logistical inefficiencies. However, little is known about how this initiative has affected the quality of ED care from the perspectives of patients and healthcare professionals.

Aim: To evaluate the quality of health services in the ED from the patients' and health professional's perspectives.

Methods: A qualitative design was employed using purposive sampling. Semi-structured interviews were conducted with 32 patients and 24 health professionals across 11 public hospitals (three rural and eight urban) in Jeddah between November 2023 and January 2024. Interviews were conducted face-to-face or by phone in Arabic or English, recorded with consent, and analyzed thematically.

Findings: Participants highlighted the importance of the "Door to Disposition" initiative and its valuable implementation. On the other hand, the primary reported barriers to emergency quality care provision are the absence of an effective triage system, shortage of medical practitioners, long waiting times, lack of dedicated urgent care centers, and lack of resources and logistical support. Thus, participants suggested improving emergency department services by focusing on primary and secondary care centers in terms of essential services and supplies, increasing the physical and human capacity of hospitals, establishing affiliated urgent care centers, providing effective and efficient means of communication between primary and secondary care centers, and finally, continually developing the healthcare providers capabilities.

Conclusion: The study helped to identify the barriers and facilitators encountered by patients and health professionals when accessing and utilizing emergency care in Jeddah.

背景:在世界各地的医院中,急诊科(ED)在提供救生服务方面发挥着至关重要的作用。在沙特阿拉伯吉达省,卫生部引入了“处置之门”关键绩效指标(KPI),通过解决过度拥挤、床位容量有限、患者转移延误以及复杂的后勤效率低下等问题,提高急诊科服务质量。然而,从患者和医疗保健专业人员的角度来看,人们对这一举措如何影响ED护理质量知之甚少。目的:从患者和卫生专业人员的角度评价急诊科的卫生服务质量。方法:采用目的抽样的定性设计。在2023年11月至2024年1月期间,对吉达11家公立医院(3家农村医院和8家城市医院)的32名患者和24名卫生专业人员进行了半结构化访谈。访谈用阿拉伯语或英语面对面或电话进行,征得同意后录音,并按主题进行分析。调查结果:与会者强调了“处置之门”倡议的重要性及其有价值的实施。另一方面,据报道,提供高质量紧急护理的主要障碍是缺乏有效的分诊系统,医生短缺,等待时间长,缺乏专门的紧急护理中心,以及缺乏资源和后勤支持。因此,与会者建议提高急诊科服务水平,重点关注初级和二级医疗中心的基本服务和物资供应,提高医院的物力和人力能力,建立附属急诊科中心,在初级和二级医疗中心之间提供有效和高效的沟通手段,最后,不断发展医疗服务提供者的能力。结论:该研究有助于确定患者和卫生专业人员在吉达获得和利用紧急护理时遇到的障碍和促进因素。
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引用次数: 0
Effect of an Educational Intervention on Knowledge and Skills of Police Officers Towards Prehospital Care for Road Traffic Accident Victims in Southwestern Uganda. 教育干预对乌干达西南部道路交通事故受害者院前护理警察知识和技能的影响
IF 1.5 Q3 EMERGENCY MEDICINE Pub Date : 2025-10-17 eCollection Date: 2025-01-01 DOI: 10.2147/OAEM.S522213
Loyce Kyarikunda, Philis Chelimo, Shamia Nakabugo, Daphine Asaasira, Jacob Twinamatsiko, Frank Senyondo, Leevan Tibaijuka, Mzee Kaana Charles, JohnBosco Birungi, Vallence Niyonzima

Background: Road traffic injuries pose a significant public health challenge in Sub-Saharan Africa, particularly Uganda. Due to limited emergency medical services, police officers and bystanders provide inadequate prehospital care, contributing to high mortality rates of road traffic accident victims. The study evaluated the effect of an educational intervention on the knowledge and skills of police officers towards prehospital care for RTA victims in Southwestern Uganda.

Methodology: The study was conducted at Mbarara Central Police Station using a quasi-experimental design. We recruited a convenience sample of 45 participants who had served for at least 6 months and provided informed consent to participate. Data were collected using a validated structured questionnaire and checklist. Analysis was done using Stata version 17, with variables scoring a p-value of 0.001, which was considered significant utilizing a t-test.

Results: The majority (80%) of the participants were men, mean age was 41.2±11.3 years. Baseline knowledge and skills in prehospital care were low, with mean scores of 50.7%±16.8 and 34.0%±8.1 respectively. Post-intervention, there was a significant improvement in knowledge by 15.4% and skills by 46.4%, which was statistically significant (P<0.001). Improvement was most notable in the secondary survey by 67% for skills and least in the assessment for major bleeding by 18.5% for knowledge.

Conclusion and recommendations: The study found that an educational intervention greatly enhanced police officers' prehospital care skills for RTA victims, recommending regular training for Police officers as first responders.

背景:道路交通伤害对撒哈拉以南非洲,特别是乌干达的公共卫生构成重大挑战。由于紧急医疗服务有限,警察和旁观者提供的院前护理不足,导致道路交通事故受害者死亡率高。该研究评估了教育干预对乌干达西南部警察院前护理RTA受害者的知识和技能的影响。方法:本研究在姆巴拉拉中央警察局采用准实验设计进行。我们招募了45名服务至少6个月并提供知情同意参与的参与者作为方便样本。使用有效的结构化问卷和检查表收集数据。使用Stata version 17进行分析,变量的p值为0.001,使用t检验。结果:大多数(80%)参与者为男性,平均年龄为41.2±11.3岁。院前护理的基线知识和技能较低,平均得分分别为50.7%±16.8分和34.0%±8.1分。干预后,警察的知识和技能分别提高了15.4%和46.4%,差异有统计学意义(p)结论和建议:研究发现,教育干预大大提高了警察对RTA受害者的院前护理技能,建议对警察进行定期的急救培训。
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引用次数: 0
Early Prophylactic Anticoagulation and In-Hospital Mortality in Patients with Severe Acute Pancreatitis: A Retrospective Cohort Study. 重症急性胰腺炎患者早期预防性抗凝和住院死亡率:一项回顾性队列研究
IF 1.5 Q3 EMERGENCY MEDICINE Pub Date : 2025-10-04 eCollection Date: 2025-01-01 DOI: 10.2147/OAEM.S539104
Haodong Zhao, Hui Liu, Jiongjiong Cheng, Jia Chen, Shuo Li, Yaowei Sun, Yu Wang

Purpose: To investigate the association between early prophylactic anticoagulation and in-hospital mortality in ICU patients with severe acute pancreatitis.

Patients and methods: This retrospective cohort study used data from the MIMIC-IV database (v3.1), including adult ICU patients diagnosed with SAP between 2008 and 2019. Patients receiving therapeutic anticoagulation were excluded. Early prophylactic anticoagulation was defined as subcutaneous heparin or enoxaparin administered within 24 hours of ICU admission. The primary outcome was in-hospital mortality. Multivariable Cox regression models with multiple imputation and propensity score matching were used to adjust for confounding.

Results: Among 1341 eligible patients, 286 (21.3%) received early prophylactic anticoagulation. While crude in-hospital mortality was not significantly different between groups, patients receiving early anticoagulation had significantly lower in-hospital mortality (Log-rank P = 0.015). Multivariable Cox models confirmed a consistent protective association across imputed datasets (HRs ranging from 0.60 to 0.62; all P < 0.05). Subgroup analysis showed no significant interaction across age, gender, or comorbidity status. After 1:1 propensity score matching (n = 284 pairs), the mortality benefit persisted (HR = 0.51; 95% CI: 0.32-0.82; P = 0.005). Additional sensitivity analyses yielded similar results.

Conclusion: Early prophylactic anticoagulation within 24 hours of ICU admission was associated with reduced in-hospital mortality in patients with severe acute pancreatitis. These findings suggest potential benefits of early anticoagulation in this high-risk population and warrant further prospective validation.

目的:探讨重症急性胰腺炎ICU患者早期预防性抗凝治疗与住院死亡率的关系。患者和方法:这项回顾性队列研究使用了MIMIC-IV数据库(v3.1)的数据,包括2008年至2019年间诊断为SAP的成年ICU患者。排除接受治疗性抗凝治疗的患者。早期预防性抗凝定义为在ICU入院24小时内皮下给予肝素或依诺肝素。主要终点是住院死亡率。采用多变量Cox回归模型进行多重输入和倾向评分匹配,以调整混杂因素。结果:1341例符合条件的患者中,286例(21.3%)接受了早期预防性抗凝治疗。虽然两组之间的住院死亡率无显著差异,但早期抗凝治疗患者的住院死亡率显著降低(Log-rank P = 0.015)。多变量Cox模型证实了输入数据集之间一致的保护性关联(hr范围为0.60至0.62,均P < 0.05)。亚组分析显示,年龄、性别或合并症状态之间没有显著的相互作用。经1:1倾向评分匹配(n = 284对)后,死亡率获益持续存在(HR = 0.51; 95% CI: 0.32-0.82; P = 0.005)。另外的敏感性分析也得出了类似的结果。结论:重症急性胰腺炎患者入院24小时内早期预防性抗凝可降低住院死亡率。这些发现提示在高危人群中早期抗凝治疗的潜在益处,需要进一步的前瞻性验证。
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引用次数: 0
Challenges in the Literature Around Context-Sensitive Implementation of Shared Decision Making in Emergency Medicine: A Scoping Review. 围绕急诊医学中情境敏感的共享决策实施的文献挑战:范围回顾。
IF 1.5 Q3 EMERGENCY MEDICINE Pub Date : 2025-09-13 eCollection Date: 2025-01-01 DOI: 10.2147/OAEM.S516347
Felix Wehking, Friedemann Geiger, Fueloep Scheibler, Constanze Stolz-Klingenberg, Ina Monsef, Daniel Litsch, Stefanie Hemmer, Jan-Christoph Lewejohann

Background: Shared decision making is a healthcare method in which health personnel and patients collaboratively evaluate different management options for medical decisions. Despite possible restraints this method encounters in the context of emergency medicine, there is a growing body of evidence. This article critically appraises the current literature and challenges to inform future research efforts.

Methods: This scoping review respects the PRISMA- and PECOS-methodologies. Qualitative- and quantitative studies were included when exposing emergency health personnel or patients to collaborative care for medical decisions with multiple reasonable management options. PubMed, CENTRAL, APA PsycINFO, Web of Science, reference lists and research group remarks served as data sources. Three researchers handled title- and abstract screening; one researcher extracted and synthesized data. Basic data on study design, publication date, country of origin, estimates for time consumption and more were extracted through standardized forms for all publications. All outcomes from the randomized clinical trials were included and reported, following the authors' conclusions. This includes effects on consultation times. Through tabular visualization, critical appraisal and author group discussions, challenges in the literature were summarized narratively. Neither risk of bias assessment nor meta-analysis were performed.

Results: Of 3954 hits, 3428 remained for the title- and abstract screening and 67 for data synthesis. Studies predominantly utilized observational designs (n=27), originated from the USA (n=50) and were published between 2011 and 2020 (n=46). The included randomized trials (n=6) report heterogeneous results on patient-reported outcome measures and resource utilization. Patient safety was reported as not affected. In three randomized trials, consultations were prolonged by 2 minutes on average. Through critical appraisal and author group discussions, six annotations on the literature on shared decision making in emergency medicine were stipulated.

Conclusion: Research on shared decision making in emergency medicine utilizes different, intertwined terminologies, originates mostly from the USA and focuses on decision aids. The few randomized trials exclude high-risk patients and suggest potential resource-saving effects without compromising patient safety. The formal increase in discussion times appears debatable.

背景:共享决策是一种医疗保健方法,其中卫生人员和患者协同评估不同的医疗决策管理方案。尽管这种方法在急诊医学中可能受到限制,但有越来越多的证据。本文批判性地评价了当前的文献和挑战,以告知未来的研究工作。方法:本综述尊重PRISMA-和pecos -方法。定性和定量研究包括在让急诊卫生人员或患者接受协作护理的医疗决策与多种合理的管理方案。PubMed, CENTRAL, APA PsycINFO, Web of Science,参考文献列表和研究小组评论作为数据来源。三位研究人员负责标题和摘要筛选;一名研究人员提取并合成了数据。通过标准化表格提取所有出版物的研究设计、出版日期、原产国、估计时间消耗等基本数据。根据作者的结论,纳入并报告了随机临床试验的所有结果。这包括对咨询时间的影响。通过表格可视化、批判性评价和作者小组讨论,对文献中的挑战进行了叙述总结。未进行偏倚风险评估和meta分析。结果:在3954个点击中,3428个用于标题和摘要筛选,67个用于数据合成。研究主要采用观察性设计(n=27),来自美国(n=50),发表于2011年至2020年之间(n=46)。纳入的随机试验(n=6)报告了患者报告的结局测量和资源利用的不同结果。据报道,患者安全未受影响。在三个随机试验中,会诊时间平均延长了2分钟。通过批判性评价和作者小组讨论,对急诊医学共享决策的文献进行了六项批注。结论:急诊医学共享决策的研究使用不同且相互交织的术语,主要起源于美国,并侧重于决策辅助。少数随机试验排除了高风险患者,并提示在不损害患者安全的情况下可能节省资源。正式增加讨论时间似乎值得商榷。
{"title":"Challenges in the Literature Around Context-Sensitive Implementation of Shared Decision Making in Emergency Medicine: A Scoping Review.","authors":"Felix Wehking, Friedemann Geiger, Fueloep Scheibler, Constanze Stolz-Klingenberg, Ina Monsef, Daniel Litsch, Stefanie Hemmer, Jan-Christoph Lewejohann","doi":"10.2147/OAEM.S516347","DOIUrl":"10.2147/OAEM.S516347","url":null,"abstract":"<p><strong>Background: </strong>Shared decision making is a healthcare method in which health personnel and patients collaboratively evaluate different management options for medical decisions. Despite possible restraints this method encounters in the context of emergency medicine, there is a growing body of evidence. This article critically appraises the current literature and challenges to inform future research efforts.</p><p><strong>Methods: </strong>This scoping review respects the PRISMA- and PECOS-methodologies. Qualitative- and quantitative studies were included when exposing emergency health personnel or patients to collaborative care for medical decisions with multiple reasonable management options. PubMed, CENTRAL, APA PsycINFO, Web of Science, reference lists and research group remarks served as data sources. Three researchers handled title- and abstract screening; one researcher extracted and synthesized data. Basic data on study design, publication date, country of origin, estimates for time consumption and more were extracted through standardized forms for all publications. All outcomes from the randomized clinical trials were included and reported, following the authors' conclusions. This includes effects on consultation times. Through tabular visualization, critical appraisal and author group discussions, challenges in the literature were summarized narratively. Neither risk of bias assessment nor meta-analysis were performed.</p><p><strong>Results: </strong>Of 3954 hits, 3428 remained for the title- and abstract screening and 67 for data synthesis. Studies predominantly utilized observational designs (n=27), originated from the USA (n=50) and were published between 2011 and 2020 (n=46). The included randomized trials (n=6) report heterogeneous results on patient-reported outcome measures and resource utilization. Patient safety was reported as not affected. In three randomized trials, consultations were prolonged by 2 minutes on average. Through critical appraisal and author group discussions, six annotations on the literature on shared decision making in emergency medicine were stipulated.</p><p><strong>Conclusion: </strong>Research on shared decision making in emergency medicine utilizes different, intertwined terminologies, originates mostly from the USA and focuses on decision aids. The few randomized trials exclude high-risk patients and suggest potential resource-saving effects without compromising patient safety. The formal increase in discussion times appears debatable.</p>","PeriodicalId":45096,"journal":{"name":"Open Access Emergency Medicine","volume":"17 ","pages":"267-287"},"PeriodicalIF":1.5,"publicationDate":"2025-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12442812/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145087765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of "Real BVM Help" for Improving Manual Ventilation Quality in the Prehospital Setting: A Before-After Manikin Study. “真实BVM帮助”对院前人工通气质量改善的评价:一项前后人体研究
IF 1.5 Q3 EMERGENCY MEDICINE Pub Date : 2025-09-11 eCollection Date: 2025-01-01 DOI: 10.2147/OAEM.S520921
Mario Krammel, Daniel Grassmann, Lukas Heinrich, Roman Brock, Andrea Kornfehl, Nikolaus Pagitz, Karolina Valentova, Christoph Veigl, Sabine Heider, Michael Girsa, Patrick Aigner, Thomas Hamp, Sebastian Schnaubelt

Background: Manual ventilation is a critical skill for emergency medical service (EMS) members. However, it is challenging in terms of correct ventilation rates and tidal volumes, with potentially severe adverse effects of hypo- and hyperventilation. Measuring the quality and involving real-time feedback may be effective in optimizing of manual ventilation.

Methods: Data acquired retrospectively from a quality management project in 143 advanced emergency medical technicians were included. They performed bag ventilations on an intubated adult manikin for two minutes without any feedback system, and then another two minutes with the Real BVM Help® device. Ventilation rates and volumes and their allocation in correct/recommended ranges were determined.

Results: With the feedback device, correctly applied ventilation rates increased by 21% (63.6% in the correct range without vs 84.6% with the feedback device; p<0.001), and ventilation volumes improved by 41% (27% in the correct range without vs 68% with the feedback device; p<0.001). Without the device, the average ventilation rate was 10.5 ±3.1/minute, compared to 9.5 ±1.9/minute with the device. Ventilation volumes amounted to 370.6 ±84 mL without Real BVM Help®, while when using it, 415.5 ±33.1 mL was noted.

Conclusion: Our data demonstrate significant improvements in ventilation rates and volumes when using a ventilation feedback device. This manikin study suggests a ventilation feedback device being beneficial for the use by EMS members, but our findings must be further validated in real-life conditions.

背景:手动通气是紧急医疗服务(EMS)成员的一项关键技能。然而,在正确的通气率和潮气量方面是具有挑战性的,并且可能存在通气不足和过度通气的严重不良影响。测量通气质量并引入实时反馈可能是优化人工通气的有效方法。方法:回顾性分析143名高级急救技术人员质量管理项目资料。他们在没有任何反馈系统的情况下对插管的成人假人进行了两分钟的袋式通气,然后使用Real BVM Help®设备进行了两分钟的通气。确定了通风率和容积及其在正确/推荐范围内的分配。结果:使用反馈装置时,正确应用通气率提高了21%(未使用时为63.6%,使用反馈装置时为84.6%;p®,使用时为415.5±33.1 mL。结论:我们的数据表明,当使用通风反馈装置时,通气率和通气量有显著改善。这项人体模型研究表明,通风反馈装置对EMS成员的使用是有益的,但我们的发现必须在现实生活条件下进一步验证。
{"title":"Evaluation of \"Real BVM Help\" for Improving Manual Ventilation Quality in the Prehospital Setting: A Before-After Manikin Study.","authors":"Mario Krammel, Daniel Grassmann, Lukas Heinrich, Roman Brock, Andrea Kornfehl, Nikolaus Pagitz, Karolina Valentova, Christoph Veigl, Sabine Heider, Michael Girsa, Patrick Aigner, Thomas Hamp, Sebastian Schnaubelt","doi":"10.2147/OAEM.S520921","DOIUrl":"10.2147/OAEM.S520921","url":null,"abstract":"<p><strong>Background: </strong>Manual ventilation is a critical skill for emergency medical service (EMS) members. However, it is challenging in terms of correct ventilation rates and tidal volumes, with potentially severe adverse effects of hypo- and hyperventilation. Measuring the quality and involving real-time feedback may be effective in optimizing of manual ventilation.</p><p><strong>Methods: </strong>Data acquired retrospectively from a quality management project in 143 advanced emergency medical technicians were included. They performed bag ventilations on an intubated adult manikin for two minutes without any feedback system, and then another two minutes with the Real BVM Help<sup>®</sup> device. Ventilation rates and volumes and their allocation in correct/recommended ranges were determined.</p><p><strong>Results: </strong>With the feedback device, correctly applied ventilation rates increased by 21% (63.6% in the correct range without vs 84.6% with the feedback device; p<0.001), and ventilation volumes improved by 41% (27% in the correct range without vs 68% with the feedback device; p<0.001). Without the device, the average ventilation rate was 10.5 ±3.1/minute, compared to 9.5 ±1.9/minute with the device. Ventilation volumes amounted to 370.6 ±84 mL without Real BVM Help<sup>®</sup>, while when using it, 415.5 ±33.1 mL was noted.</p><p><strong>Conclusion: </strong>Our data demonstrate significant improvements in ventilation rates and volumes when using a ventilation feedback device. This manikin study suggests a ventilation feedback device being beneficial for the use by EMS members, but our findings must be further validated in real-life conditions.</p>","PeriodicalId":45096,"journal":{"name":"Open Access Emergency Medicine","volume":"17 ","pages":"257-265"},"PeriodicalIF":1.5,"publicationDate":"2025-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12435499/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145076379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Open Access Emergency Medicine
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