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Immunomodulation Effect of Convalescent Plasma Therapy in Severe - Critical COVID-19 Patients. 恢复期血浆治疗对重症COVID-19患者的免疫调节作用。
IF 1.5 Q2 Nursing Pub Date : 2023-01-01 DOI: 10.2147/OAEM.S405555
Munawaroh Fitriah, Aditea Etnawati Putri, Bambang Pujo Semedi, Atika Atika, Betty Agustina Tambunan
Introduction Convalescent plasma therapy (CPT) is an alternative therapy for managing COVID-19, but its use is still controversial. Objective Analyzing the effectiveness of CPT in modulating immune responses based on SARS-COV-2 anti-spike protein receptor-binding domain (s-RBD) IgG, inflammatory cytokines (IL-6 and IL-4), and mortality in severe-critical COVID-19 patients. Methods This study was an observational analytical with a prospective cohort design. The number of participants was 39 patients from June to December 2020. The participants received CPT and was tested for blood analysis such as IL-4, IL-6 and s-RBD IgG. The data were taken a day before CPT, 1st day, 2nd day, and 7th day after CPT. The analysis included Friedman, Pearson correlation, and Mann–Whitney test which is significant if p <0.05. Results The value of participant’s s-RBD IgG before CPT was 91.49 (0.43–3074.73) AU/mL and the 7th day post-CPT, s-RBD IgG value of 1169.79 (6.48–5577.91) AU/mL (p <0.001). The IL-4 value before CPT was 1.78 (0.85–5.21) ng/mL and the 7th day post-CPT, IL-4 value of 1.97 (0.87–120.30) ng/mL (p = 0.401). The condition was also found in IL-6 value, in which the IL-4 value participant before CPT was 109.61 (0.73–4701.63) ng/mL and the 7th day post-CPT, IL-6 value of 1.97 (0.87–120.30) ng/mL (p = 0.401). No significant correlation found between increased s-RBD IgG level with increased IL-4 and decreased IL-6 before and after CPT in severe-critical COVID-19 patients (p >0.05). No significant correlation was also found between increased s-RBD IgG levels, IL-4 too, and decreased IL-6 after CPT therapy between deceased and alive patients, both in 1st, 2nd, and 7th days (p >0.05). Conclusion No correlation between the increase in s-RBD IgG levels and changes in IL-4 and IL-6 levels. Changes in s-RBD IgG, IL-4, and IL-6 levels are not associated with mortality in severe-critical COVID-19 degree post CPT recipients.
恢复期血浆治疗(CPT)是一种治疗COVID-19的替代疗法,但其使用仍存在争议。目的:分析CPT对SARS-COV-2抗刺突蛋白受体结合域(s-RBD) IgG、炎症因子(IL-6、IL-4)及COVID-19重症患者死亡率的调节作用。方法:本研究采用前瞻性队列设计的观察性分析方法。2020年6月至12月,参与者人数为39名患者。参与者接受CPT治疗,并进行血液分析,如IL-4、IL-6和s-RBD IgG。分别于CPT前1天、CPT后第1天、第2天、第7天采集数据。结果:CPT前s-RBD IgG值为91.49 (0.43-3074.73)AU/mL, CPT后第7天s-RBD IgG值为1169.79 (6.48-5577.91)AU/mL (p = 0.401)。IL-6值也有差异,CPT前IL-4值为109.61 (0.73-4701.63)ng/mL, CPT后第7天IL-6值为1.97 (0.87-120.30)ng/mL (p = 0.401)。重症COVID-19患者CPT前后s-RBD IgG水平升高与IL-4升高、IL-6降低无显著相关性(p >0.05)。CPT治疗后1、2、7天死亡与存活患者s-RBD IgG水平升高、IL-4水平升高、IL-6水平降低均无显著相关性(p >0.05)。结论:s-RBD IgG水平升高与IL-4、IL-6水平变化无相关性。重症COVID-19度CPT后患者s-RBD IgG、IL-4和IL-6水平的变化与死亡率无关。
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引用次数: 1
Risks of Early Mortality and Associated Factors at Adult Emergency Department of Jimma University Medical Center. 吉马大学医学中心成人急诊科早期死亡风险及相关因素分析。
IF 1.5 Q2 Nursing Pub Date : 2023-01-01 DOI: 10.2147/OAEM.S420660
Fikadu Abebe, Asaminew Habtamu, Abdata Workina

Introduction: Mortality in the emergency department is still high in developing countries with resources scarce. Most of emergency department mortality occurred within the first three days; the majority of these deaths are avoidable with proper intervention. Therefore, the purpose of this study was to assess the mortality risks and therapeutic benefits of early and late death.

Methods: Case-control study approach with 87 cases and 174 controls (case to control ratio of 1:2) was used on 261 study participants. Data were extracted from the patient charts using a pretested extraction tool. Then, checked data were entered into Epi-data manager 4.6 versions and analyzed using SPSS 25 versions. Binary logistic regression was used to construct bivariate and multivariable analyses following the descriptive analysis. Finally, a predictor variable in the multivariate logistic regression was deemed to have a significant association if its P-value was less than 0.05 at a 95% confidence level.

Results: Patients who were triaged into the red zone had a 2.3-fold greater risk of dying early than those who were placed in another triage category [(AOR=2.3; 95% CI: 1.10, 5.55) P=0.001]. Besides, having cardiovascular disease (AOR=4.79; 95% CI: 1.73, 13.27), age ≥65 years [(AOR=3.2; 95% CI: 1.74, 7.23) P=0.003)], having rural residency (AOR=6.57; 95% CI: 1.39, 31.13), and having been diagnosed with respiratory failure [(AOR=3.2; 95% CI: 1.04, 7.69), P=0.013)] were associated with early mortality.

Conclusion: The common causes of early mortality were respiratory failure, cardiovascular disease, and road traffic accident. Being aged, having rural residence, being triaged into red zone, and diagnosed for respiratory failure and cardiac failure increase early mortality compared with late death.

在资源匮乏的发展中国家,急诊科的死亡率仍然很高。大多数急诊科死亡发生在头三天内;通过适当的干预,这些死亡中的大多数是可以避免的。因此,本研究的目的是评估早死和晚死的死亡率风险和治疗益处。方法:采用病例-对照研究方法,纳入病例87例,对照174例(病例与对照比1:2),共261例。使用预先测试的提取工具从患者图表中提取数据。然后将检查后的数据输入Epi-data manager 4.6版本,使用SPSS 25版本进行分析。在描述性分析之后,采用二元逻辑回归构建双变量和多变量分析。最后,在多元逻辑回归中,如果p值在95%置信水平下小于0.05,则认为预测变量具有显著相关性。结果:分类为红色区域的患者比分类为其他类别的患者早死的风险高2.3倍[(AOR=2.3;95% ci: 1.10, 5.55) p =0.001]。此外,有心血管疾病(AOR=4.79;95% CI: 1.73, 13.27),年龄≥65岁[AOR=3.2;95% CI: 1.74, 7.23) P=0.003)],有农村户口(AOR=6.57;95% CI: 1.39, 31.13),并被诊断为呼吸衰竭[(AOR=3.2;(95% CI: 1.04, 7.69), P=0.013)]与早期死亡率相关。结论:早期死亡的常见原因是呼吸衰竭、心血管疾病和道路交通事故。与晚期死亡相比,老年、农村居住、被划分为红色区域、被诊断为呼吸衰竭和心力衰竭的早期死亡率增加。
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引用次数: 0
Cutaneous Impact Location Predicts Intracranial Injury Among the Elderly Population with Traumatic Brain Injury. 皮肤撞击位置预测老年人外伤性脑损伤的颅内损伤。
IF 1.5 Q2 Nursing Pub Date : 2023-01-01 DOI: 10.2147/OAEM.S422785
Marián Sedlák, Adonis Wazir, Aikaterini Dima, Jakub Gazda, Radoslav Morochovič

Background: Traumatic brain injury (TBI) is one of the most common trauma-related diagnoses among the elderly population treated in emergency departments (ED). Identification of patients with increased or decreased risk of intracranial bleeding is of clinical importance. The objective of this study was to evaluate the implication of cutaneous impact location (CIL) on the prevalence of intracranial injury after suspected or confirmed TBI irrespective of its severity.

Methods: This was a retrospective, single-center, descriptive observational study of geriatric patients aged 65 years and older treated for suspected or confirmed TBI in a trauma surgery ED. The primary outcome of the study was the assessment of a CIL of the injury and its association with the prevalence of intracranial lesions found on a head computed tomography scan.

Results: Among 381 patients included in the analysis, the CIL of interest (temporo-parietal and occipital impacts) was present among 178 (46.7%) cases. Thirty-six (9.5%) patients were diagnosed with intracranial bleeding. The prevalence of intracranial bleeding was higher in the CIL of interest group compared with other locations outside (12.9% vs 6.4%; p = 0.030). CIL of interest was a predictor of intracranial bleeding (p = 0.033; OR: 2.17; 95% CI: 1.06 to 4.42).

Conclusion: The CIL of head injury is a predictor of intracranial lesions among geriatric patients with traumatic brain injury. Physicians should be aware of this association when assessing elderly patients with head injuries. More studies are needed to develop a clinical management tool incorporating CIL to guide the diagnosis of TBI in this population.

背景:创伤性脑损伤(TBI)是在急诊科(ED)治疗的老年人中最常见的创伤相关诊断之一。鉴别颅内出血风险增加或减少的患者具有重要的临床意义。本研究的目的是评估皮肤撞击位置(CIL)对疑似或确诊TBI后颅内损伤发生率的影响,无论其严重程度如何。方法:这是一项回顾性、单中心、描述性观察性研究,研究对象是在创伤外科急诊科中因疑似或确诊TBI而接受治疗的65岁及以上老年患者。该研究的主要结果是评估损伤的CIL及其与头部计算机断层扫描发现的颅内病变发生率的关系。结果:在纳入分析的381例患者中,178例(46.7%)存在感兴趣的CIL(颞顶骨和枕部撞击)。36例(9.5%)患者诊断为颅内出血。颅内出血发生率在CIL兴趣组高于其他部位(12.9% vs 6.4%;P = 0.030)。感兴趣的CIL是颅内出血的预测因子(p = 0.033;OR: 2.17;95% CI: 1.06 ~ 4.42)。结论:颅脑损伤CIL可作为老年颅脑损伤患者颅内病变的预测指标。医生在评估老年颅脑损伤患者时应该意识到这种关联。需要更多的研究来开发一种结合CIL的临床管理工具来指导该人群的TBI诊断。
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引用次数: 0
Accuracy of Trauma on Scene Triage Screening Tool (Shock Index, Reverse Shock Index Glasgow Coma Scale and National Early Warning Score) to Predict the Severity of Emergency Department Triage: A Retrospective Cross-Sectional Study. 创伤现场分诊筛查工具(休克指数、逆休克指数格拉斯哥昏迷量表和国家早期预警评分)预测急诊科分诊严重程度的准确性:一项回顾性横断面研究
IF 1.5 Q2 Nursing Pub Date : 2023-01-01 DOI: 10.2147/OAEM.S403545
Chaiyaporn Yuksen, Chuenruthai Angkoontassaneeyarat, Sorawat Thananupappaisal, Thanakorn Laksanamapune, Malivan Phontabtim, Pamorn Namsanor

Introduction: Prehospital trauma care includes on-scene assessments, essential treatment, and facilitating transfer to an appropriate trauma center to deliver optimal care for trauma patients. While the Simple Triage and Rapid Treatment (START), Revised Triage Sieve (rTS), and National Early Warning Score (NEWS) tools are user-friendly in a prehospital setting, there is currently no standardized on-scene triage protocol in Thailand Emergency Medical Service (EMS). Therefore, this study aims to evaluate the precision of these tools (SI, rSIG, and NEWS) in predicting the severity of trauma patients who are transferred to the emergency department (ED).

Methods: This study was a retrospective cross-sectional and diagnostic research conducted on trauma patients transferred by EMS to the ED of Ramathibodi Hospital, a university-affiliated super tertiary care hospital in Bangkok, Thailand, from January 2015 to September 2022. We compared the on-scene triage tool (SI, rSIG, and NEWS) and ED triage tool (Emergency Severity Index) parameters, massive transfusion protocol (MTP), and intensive care unit (ICU) admission with the area under ROC (univariable analysis) and diagnostic odds ratio (multivariable logistic regression analysis). The optimal cut-off threshold for the best parameter was determined by selecting the value that produced the highest area under the ROC curve.

Results: A total of 218 patients were traumatic patients transported by EMS to the ED, out of which 161 were classified as ESI levels 1-2, while the remaining 57 patients were categorized as levels 3-5 on the ESI triage scale. We found that NEWS was a more accurate triage tool to discriminate the severity of trauma patients than rSIG and SI. The area under the ROC was 0.74 (95% CI 0.70-0.79) (OR 18.98, 95% CI 1.06-337.25), 0.65 (95% CI 0.59-0.70) (OR 1.74, 95% CI 0.17-18.09) and 0.58 (95% CI 0.52-0.65) (OR 0.28, 95% CI 0.04-1.62), respectively (P-value <0.001). The cut point of NEWS to discriminate ESI levels 1-2 and levels 3-5 was >6 points.

Conclusion: NEWS is the best on-scene triage screening tool to predict the severity at the emergency department, massive transfusion protocol (MTP), and intensive care unit (ICU) admission compared with other triage tools SI and rSIG.

院前创伤护理包括现场评估、基本治疗和促进转移到适当的创伤中心,为创伤患者提供最佳护理。虽然简单分诊和快速治疗(START)、修订分诊筛(rTS)和国家预警评分(NEWS)工具在院前环境中是用户友好的,但泰国紧急医疗服务(EMS)目前没有标准化的现场分诊协议。因此,本研究旨在评估这些工具(SI、rSIG和NEWS)在预测转至急诊科(ED)的创伤患者严重程度方面的准确性。方法:本研究对2015年1月至2022年9月泰国曼谷大学附属三级医院Ramathibodi医院急诊急诊急诊急诊的创伤患者进行回顾性横断面和诊断研究。我们比较了现场分诊工具(SI、rSIG和NEWS)和急诊科分诊工具(急诊严重程度指数)参数、大量输血方案(MTP)和重症监护病房(ICU)入院与ROC下面积(单变量分析)和诊断优势比(多变量logistic回归分析)。通过选择在ROC曲线下产生最大面积的值来确定最佳参数的最佳截止阈值。结果:218例急诊创伤患者均为EMS转运至急诊科,其中ESI 1-2级161例,其余57例为ESI 3-5级。我们发现NEWS是一种比rSIG和SI更准确的区分创伤患者严重程度的分类工具。ROC下面积分别为0.74 (95% CI 0.70-0.79) (OR 18.98, 95% CI 1.06-337.25)、0.65 (95% CI 0.59-0.70) (OR 1.74, 95% CI 0.17-18.09)和0.58 (95% CI 0.52-0.65) (OR 0.28, 95% CI 0.04-1.62) (p值6点)。结论:与其他分诊工具SI和rSIG相比,NEWS是预测急诊科严重程度、大量输血方案(MTP)和重症监护病房(ICU)入院的最佳现场分诊筛查工具。
{"title":"Accuracy of Trauma on Scene Triage Screening Tool (Shock Index, Reverse Shock Index Glasgow Coma Scale and National Early Warning Score) to Predict the Severity of Emergency Department Triage: A Retrospective Cross-Sectional Study.","authors":"Chaiyaporn Yuksen,&nbsp;Chuenruthai Angkoontassaneeyarat,&nbsp;Sorawat Thananupappaisal,&nbsp;Thanakorn Laksanamapune,&nbsp;Malivan Phontabtim,&nbsp;Pamorn Namsanor","doi":"10.2147/OAEM.S403545","DOIUrl":"https://doi.org/10.2147/OAEM.S403545","url":null,"abstract":"<p><strong>Introduction: </strong>Prehospital trauma care includes on-scene assessments, essential treatment, and facilitating transfer to an appropriate trauma center to deliver optimal care for trauma patients. While the Simple Triage and Rapid Treatment (START), Revised Triage Sieve (rTS), and National Early Warning Score (NEWS) tools are user-friendly in a prehospital setting, there is currently no standardized on-scene triage protocol in Thailand Emergency Medical Service (EMS). Therefore, this study aims to evaluate the precision of these tools (SI, rSIG, and NEWS) in predicting the severity of trauma patients who are transferred to the emergency department (ED).</p><p><strong>Methods: </strong>This study was a retrospective cross-sectional and diagnostic research conducted on trauma patients transferred by EMS to the ED of Ramathibodi Hospital, a university-affiliated super tertiary care hospital in Bangkok, Thailand, from January 2015 to September 2022. We compared the on-scene triage tool (SI, rSIG, and NEWS) and ED triage tool (Emergency Severity Index) parameters, massive transfusion protocol (MTP), and intensive care unit (ICU) admission with the area under ROC (univariable analysis) and diagnostic odds ratio (multivariable logistic regression analysis). The optimal cut-off threshold for the best parameter was determined by selecting the value that produced the highest area under the ROC curve.</p><p><strong>Results: </strong>A total of 218 patients were traumatic patients transported by EMS to the ED, out of which 161 were classified as ESI levels 1-2, while the remaining 57 patients were categorized as levels 3-5 on the ESI triage scale. We found that NEWS was a more accurate triage tool to discriminate the severity of trauma patients than rSIG and SI. The area under the ROC was 0.74 (95% CI 0.70-0.79) (OR 18.98, 95% CI 1.06-337.25), 0.65 (95% CI 0.59-0.70) (OR 1.74, 95% CI 0.17-18.09) and 0.58 (95% CI 0.52-0.65) (OR 0.28, 95% CI 0.04-1.62), respectively (P-value <0.001). The cut point of NEWS to discriminate ESI levels 1-2 and levels 3-5 was >6 points.</p><p><strong>Conclusion: </strong>NEWS is the best on-scene triage screening tool to predict the severity at the emergency department, massive transfusion protocol (MTP), and intensive care unit (ICU) admission compared with other triage tools SI and rSIG.</p>","PeriodicalId":45096,"journal":{"name":"Open Access Emergency Medicine","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/b8/5d/oaem-15-79.PMC10039710.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9252775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Emergency Nurses' Competency in the Emergency Department Context: A Qualitative Study. 急诊科急诊护士胜任力的质性研究。
IF 1.5 Q2 Nursing Pub Date : 2023-01-01 DOI: 10.2147/OAEM.S405923
Yanny Trisyani, Etika Emaliyawati, Ayu Prawesti, Ristina Mirwanti, Henny Suzana Mediani

Background: The availability of clear emergency nurses' competencies is critical for safe and effective emergency health care services. The study regarding emergency nurses' competencies remained virtually limited.

Purpose: This study aimed to explore the emergency nurses' competencies in the clinical emergency department (ED) context as needed by society.

Methods: This qualitative study involved focus group discussions in six groups of 54 participants from three EDs. The data were analysed using grounded theory approach including the constant comparative, interpretations, and coding procedures; initial coding, focused coding and categories.

Results: This study revealed 8 core competencies of emergency nurses: Shifting the nursing practice, Caring for acute critical patients, Communicating and coordinating, Covering disaster nursing roles, Reflecting on the ethical and legal standards, Researching competency, Teaching competencies and Leadership competencies. The interconnection of the 8 core competencies has resulted in 2 concepts of extending the ED nursing practice and demanding the advanced ED nursing role.

Conclusion: The finding reflected the community needs of nurses who work in ED settings and the need for competency development of emergency nurses.

背景:明确的急诊护士能力的可用性是安全有效的急诊医疗服务的关键。关于急诊护士能力的研究实际上仍然有限。目的:本研究旨在探讨临床急诊科(ED)情境下急诊护士应具备的社会需求。方法:本定性研究采用焦点小组讨论的方法,对来自三个急诊室的六组54名参与者进行了讨论。数据分析采用扎根理论方法,包括不断比较,解释和编码程序;初始编码,重点编码和分类。结果:本研究揭示了急诊护士的8项核心能力:转变护理实践能力、关怀急危病人能力、沟通协调能力、涵盖灾难护理角色能力、反思道德与法律标准能力、研究能力、教学能力和领导能力。8个核心能力的相互联系产生了扩展急诊科护理实践和要求高级急诊科护理角色的两个概念。结论:该调查结果反映了急诊科护士的社区需求和急诊护士能力发展的需求。
{"title":"Emergency Nurses' Competency in the Emergency Department Context: A Qualitative Study.","authors":"Yanny Trisyani,&nbsp;Etika Emaliyawati,&nbsp;Ayu Prawesti,&nbsp;Ristina Mirwanti,&nbsp;Henny Suzana Mediani","doi":"10.2147/OAEM.S405923","DOIUrl":"https://doi.org/10.2147/OAEM.S405923","url":null,"abstract":"<p><strong>Background: </strong>The availability of clear emergency nurses' competencies is critical for safe and effective emergency health care services. The study regarding emergency nurses' competencies remained virtually limited.</p><p><strong>Purpose: </strong>This study aimed to explore the emergency nurses' competencies in the clinical emergency department (ED) context as needed by society.</p><p><strong>Methods: </strong>This qualitative study involved focus group discussions in six groups of 54 participants from three EDs. The data were analysed using grounded theory approach including the constant comparative, interpretations, and coding procedures; initial coding, focused coding and categories.</p><p><strong>Results: </strong>This study revealed 8 core competencies of emergency nurses: Shifting the nursing practice, Caring for acute critical patients, Communicating and coordinating, Covering disaster nursing roles, Reflecting on the ethical and legal standards, Researching competency, Teaching competencies and Leadership competencies. The interconnection of the 8 core competencies has resulted in 2 concepts of extending the ED nursing practice and demanding the advanced ED nursing role.</p><p><strong>Conclusion: </strong>The finding reflected the community needs of nurses who work in ED settings and the need for competency development of emergency nurses.</p>","PeriodicalId":45096,"journal":{"name":"Open Access Emergency Medicine","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/a5/60/oaem-15-165.PMC10183472.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9491768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Practice of Pre-Hospital Emergency Care and Associated Factors in Addis Ababa, Ethiopia: Facility-Based Cross-Sectional Study Design. 埃塞俄比亚亚的斯亚贝巴院前急救实践及相关因素:基于设施的横断面研究设计
IF 1.5 Q2 Nursing Pub Date : 2023-01-01 DOI: 10.2147/OAEM.S424814
Azanaw Abebe, Zegeye Kebede, Dereje Bayissa Demissie

Background: Medical emergencies require quick field interventions and stabilization before transport, while rapid transportation to definitive healthcare with fewer field interventions improves trauma outcomes. Poor prehospital healthcare practices negatively impact patients' health, and limited studies exist on providers' practices in resource-limited areas like Ethiopia. This study aimed to assess the practice of pre-hospital emergency care and associated factors at pre-hospital health facilities in Addis Ababa, Ethiopia.

Methods: A facility-based cross-sectional study was conducted 191 pre-hospital healthcare providers, of which 20 randomly selected participants were participated in the observational study from October 2021 to February 2022 in Addis Ababa Ethiopia. Data was collected using a checklist and self-administered questionnaire. Data was cleaned, entered into Epi data version 4.4, and exported to SPSS software for analysis. Binary and multivariable logistic regression analyses were performed, with a P-value of 0.05 considered statistically significant.

Results: The study found that 43% (82) of pre-hospital healthcare providers in Addis Ababa, Ethiopia, had good practice in pre-hospital emergency care. The identified factors that increased the odds of good practice in pre-hospital emergency care were: being able to provide advanced life support (AOR = 88.99; 95% CI: 27.143-291.603); adequate monitoring and defibrillators (AOR = 5.829; 95% CI: 1.430-23.765); having work experience of 4-5 years (AOR = 5.86; 95% CI: 1.424-24.109); and having the opportunity to continue education (AOR = 31.953; 95% 6.479-157.591).

Conclusions and recommendations: The study found high levels of poor practice among pre-hospital healthcare providers in Addis Ababa, Ethiopia. Factors contributing to good practice include being trained in advanced Life Support, adequate monitoring, defibrillators, work experience, and having the opportunity to continue education. Therefore, policymakers and health planners should establish teaching and training centres based on Ministry of Health and Education guidelines.

背景:医疗紧急情况需要快速的现场干预和运输前的稳定,而快速运输到明确的医疗保健与较少的现场干预改善创伤的结果。不良的院前保健做法对患者健康产生负面影响,在埃塞俄比亚等资源有限的地区,对提供者做法的研究有限。本研究旨在评估埃塞俄比亚亚的斯亚贝巴院前医疗机构的院前急救实践及其相关因素。方法:对191名院前医疗服务提供者进行了基于设施的横断面研究,其中20名随机选择的参与者于2021年10月至2022年2月在埃塞俄比亚亚的斯亚贝巴参加了观察性研究。数据收集采用检查表和自我管理问卷。数据清洗后录入Epi数据4.4版,导出到SPSS软件进行分析。进行二元和多变量logistic回归分析,p值为0.05认为有统计学意义。结果:研究发现,埃塞俄比亚亚的斯亚贝巴43%(82)的院前医疗保健提供者在院前急救护理方面有良好的实践。确定的提高院前急救良好做法几率的因素是:能够提供高级生命支持(AOR = 88.99;95% ci: 27.143-291.603);足够的监测和除颤器(AOR = 5.829;95% ci: 1.430-23.765);4-5年工作经验(AOR = 5.86);95% ci: 1.424-24.109);有继续教育的机会(AOR = 31.953;95% 6.479 - -157.591)。结论和建议:研究发现,在埃塞俄比亚亚的斯亚贝巴,院前医疗服务提供者的不良做法水平很高。促进良好做法的因素包括接受高级生命支持培训、适当的监测、除颤器、工作经验以及有机会继续接受教育。因此,决策者和卫生规划人员应根据卫生部和教育部的指导方针建立教学和培训中心。
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引用次数: 0
Factors Relating to Decision Delay in the Emergency Department: Effects of Diagnostic Tests and Consultations. 与急诊科决策延迟有关的因素:诊断测试和咨询的影响。
IF 1.5 Q2 Nursing Pub Date : 2023-01-01 DOI: 10.2147/OAEM.S384774
Mustafa Gokalp Ataman, Gorkem Sariyer, Caner Saglam, Arif Karagoz, Erden Erol Unluer

Purpose: The purpose of this study is to investigate the factors increasing waiting time (WT) and length of stay (LOS) in patients, which may cause delays in decision-making in the emergency departments (ED).

Patients and methods: Patients who arrived at a training hospital in the central region of Izmir City, Turkey, during the first quarter of 2020 were retrospectively analyzed. WT and LOS were the outcome variables of the study, and gender, age, arrival type, triage level determined based on the clinical acuity, diagnosis encoded based on International Classification of Diseases-10 (ICD-10), the existence of diagnostic tests or consultation status were the identified factors. The significance of the differences in WT and LOS values based on each level of these factors was analyzed using independent sample t-tests and ANOVA.

Results: While patients for which no diagnostic testing or consultation was requested had a significantly higher WT in EDs, their LOS values were substantially lower than those for which at least one diagnostic test or consultation was ordered (p≤0.001). Besides, elderly and red zone patients and those who arrived by ambulance had significantly lower WT and higher LOS values than other levels for all groups of patients for which laboratory-type or imaging-type diagnostic test or consultation was requested (p≤0.001 for each comparison).

Conclusion: Besides ordering diagnostic tests or consultation in EDs, different factors may extend patients' WT and LOS values and cause significant decision-making delays. Understanding the patient characteristics associated with longer waiting times and LOS values and, thus, delayed decisions will enable practitioners to improve operations management in EDs.

目的:本研究的目的是探讨增加患者等待时间(WT)和住院时间(LOS)的因素,这些因素可能导致急诊科(ED)的决策延迟。患者和方法:对2020年第一季度抵达土耳其伊兹密尔市中部地区一家培训医院的患者进行回顾性分析。WT和LOS是研究的结果变量,性别、年龄、到达类型、根据临床敏锐度确定的分诊级别、根据国际疾病分类-10 (ICD-10)编码的诊断、是否存在诊断测试或咨询状态是确定的因素。采用独立样本t检验和方差分析分析各因素水平上WT和LOS值差异的显著性。结果:虽然未要求进行诊断测试或咨询的患者ed的WT明显较高,但其LOS值明显低于至少要求进行一次诊断测试或咨询的患者(p≤0.001)。此外,在所有要求进行实验室型或影像学诊断检查或咨询的患者组中,老年人和红区患者以及救护车到达的患者的WT值显著低于其他组,LOS值显著高于其他组(各比较p≤0.001)。结论:除了在急诊科进行诊断检查或咨询外,其他因素可能会延长患者的WT和LOS值,并造成重大的决策延迟。了解与较长的等待时间和LOS值相关的患者特征,从而延迟决策,将使医生能够改善急诊室的操作管理。
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引用次数: 2
Pulmonary Thromboembolism in Pregnancy: A Case Report and Literature Review. 妊娠期肺血栓栓塞1例报告及文献复习。
IF 1.5 Q2 Nursing Pub Date : 2023-01-01 DOI: 10.2147/OAEM.S404941
Gustavo Andrés Urriago-Osorio, Luis Álvaro Melo-Burbano, Juanita López-Van Den Berghe, Angela María Muñoz-Córdoba, Jorge Enrique Daza-Arana, Eduardo Contreras-Zúñiga

Data on the optimal diagnostic management of pregnant women with suspected pulmonary embolism are limited. Despite a lack of compelling evidence in some practices, clinical practice guidelines focus on the management of these patients. We present the case of a 24-year-old patient at 36 weeks of pregnancy in whom pulmonary thromboembolism (PTE) was diagnosed in a timely manner also with hemodynamic instability and echocardiographic images with clear involvement of the right cavities. She received thrombolytic therapy with alteplase 100 mg intravenously over 2 hours, which resulted in excellent outcomes for both the pregnant woman and fetus. Understanding the acute approach and management of these patients will improve our clinical practice; therefore, we reviewed a case report of a pregnant patient with high-risk PTE and compared it with current evidence. In conclusion, PE is a common disease with a high mortality rate during pregnancy. Therefore, having made a timely diagnosis using the relevant diagnostic aids and performing thrombolysis with rtPA increase the probability of survival in our patient, leading to successful results for both her and the fetus.

关于疑似肺栓塞孕妇的最佳诊断管理的数据有限。尽管在一些实践中缺乏令人信服的证据,但临床实践指南侧重于这些患者的管理。我们报告了一位24岁的怀孕36周的患者,她的肺血栓栓塞(PTE)被及时诊断为血流动力学不稳定,超声心动图显示右腔明显受累。她接受阿替普酶100毫克静脉溶栓治疗2小时,对孕妇和胎儿都有很好的结果。了解这些患者的急性方法和管理将提高我们的临床实践;因此,我们回顾了一例高危PTE孕妇的病例报告,并将其与现有证据进行比较。总之,PE是一种常见病,妊娠期死亡率高。因此,及时使用相关的诊断辅助工具进行诊断,并应用rtPA溶栓,增加了患者的生存概率,使患者和胎儿都获得了成功的结果。
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引用次数: 1
Erratum: Trends and Outcomes of Acute Poisoning in Felege Hiwot Comprehensive Specialized Hospital Medical Intensive Care Units: Retrospective Study [Corrigendum]. 校误:霍尔特大学综合专科医院重症监护病房急性中毒的趋势和结果:回顾性研究[校误]。
IF 1.5 Q2 Nursing Pub Date : 2023-01-01 DOI: 10.2147/OAEM.S404133

[This corrects the article DOI: 10.2147/OAEM.S385420.].

[这更正了文章DOI: 10.2147/OAEM.S385420.]。
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引用次数: 0
HEAR SCORE: A Proposal to Use Only Anamnestic and EKG Data to Evaluate Patients with Very Low Risk Chest Pain. 听力评分:建议仅使用记忆和心电图数据来评估极低风险胸痛患者。
IF 1.5 Q2 Nursing Pub Date : 2023-01-01 DOI: 10.2147/OAEM.S391929
Maria Lucia Mosso, Sara Montemerani
Purpose Chest pain in a common symptom in patients attending Emergency Department worldwide and can be related to an extensive variety of disorders, so it represents a diagnostic and logistic challenge for Emergency physicians. The aim of this study is to identify a subgroup of patients with a low pre-test probability of major adverse cardiac events, for which there is no need of troponin testing, to avoid potential harm from false-positive testing and long length stay in ED. Patients and Methods We retrospectively analyzed data of patients that attended ED of Siena complaining chest pain from January 2019 to August 2021. We used a modified HEART score, only evaluating history, EKG, age and risk factors. A 0–1 HEAR score was considered at very low risk for adverse cardiac events. Sensitivity, specificity, PPV, NPV and incidence of adverse cardiac events were calculated. The accuracy of HEAR score was evaluated with ROC curve. The correlation of adverse cardiac events with HEAR score 0–1 was evaluated with Fisher test. Results In this study, we included 2046 patients, of which 279 were classified at very low risk. The incidence of adverse cardiac events in this population was 0.36%. Sensibility was 97.5%, sensitivity 61%, PPV 36.8%, NPV 99.1%. The AUC for global accuracy of HEAR score was 0.945. Chi-square’s P value for the association between adverse cardiac events and HEAR score 0–1 was <0.001. Conclusion The draft presented in this study answers to the necessity to make a personalized path for patients attending ED with chest pain. The choice to avoid troponin testing may appear risky, but data from this study and from other similar show that a careful evaluation of clinical data and EKG allows to correctly discriminate which patients will not have adverse cardiac events, reducing the length of stay in ED.
目的:胸痛是世界各地急诊科就诊患者的常见症状,可能与多种疾病有关,因此对急诊医生来说,胸痛是一种诊断和后勤挑战。本研究的目的是确定一个检测前主要心脏不良事件概率低的患者亚组,这些患者不需要进行肌钙蛋白检测,以避免假阳性检测和长时间住院的潜在危害。患者和方法:我们回顾性分析了2019年1月至2021年8月在锡耶纳急诊科就诊的胸痛患者的数据。我们使用改良的HEART评分,仅评估病史、心电图、年龄和危险因素。0-1的听力评分被认为是心脏不良事件的极低风险。计算敏感性、特异性、PPV、NPV和心脏不良事件发生率。采用ROC曲线评价听力评分的准确性。采用Fisher检验评价心脏不良事件与HEAR评分0-1的相关性。结果:本研究纳入2046例患者,其中279例为极低风险。该人群心脏不良事件发生率为0.36%。敏感性97.5%,敏感性61%,PPV 36.8%, NPV 99.1%。听力评分整体准确度的AUC为0.945。心脏不良事件与HEAR评分0-1之间相关性的卡方P值为:结论:本研究提出的草案回答了为胸痛急诊科患者制定个性化路径的必要性。避免肌钙蛋白检测的选择可能看起来有风险,但本研究和其他类似研究的数据表明,仔细评估临床数据和心电图可以正确区分哪些患者不会发生不良心脏事件,从而减少在急诊科的住院时间。
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引用次数: 0
期刊
Open Access Emergency Medicine
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