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Delayed onset autoimmune cholangitis in a patient treated with pembrolizumab. 一名接受过彭博利珠单抗治疗的患者出现了迟发性自身免疫性胆管炎。
IF 0.5 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-11-01 DOI: 10.1093/bjrcr/uaae040
Joshua Newington, Daniel Patterson, Pilar Sanchez

This case study describes a female patient in her late 70s who developed autoimmune cholangitis a year after finishing 35 cycles of pembrolizumab for the treatment of her non-small cell lung cancer. The diagnosis was initially missed and delayed; the patient's agoraphobia and the COVID-19 pandemic were noted as contributing factors.

本病例研究描述了一名年过七旬的女性患者,在完成 35 个周期的 Pembrolizumab 治疗非小细胞肺癌一年后,患上了自身免疫性胆管炎。诊断最初被漏诊和延误;患者的恐旷症和 COVID-19 大流行被认为是诱因。
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引用次数: 0
Quality assessment in bone densitometry: a case of incorrect hip analysis. 骨密度测量的质量评估:一个错误的髋关节分析案例。
IF 0.5 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-10-22 eCollection Date: 2024-11-01 DOI: 10.1093/bjrcr/uaae038
Hongmin Xu, Medhat Sam Gabriel, Judy Rose James

Dual-energy X-ray absorptiometry (DXA) is a sophisticated imaging technique utilized in the field of medical diagnostics to measure bone mineral density. The significance of DXA lies in its ability to accurately assess bone health, which is crucial in the evaluation of osteoporosis, a condition characterized by weakened bones and heightened susceptibility to fractures. Despite its widespread adoption and clinical utility, DXA is not without limitations. Factors such as body size, tissue hydration, the presence of metal implants, improper equipment installation and maintenance, as well as inadequate education and training in bone densitometry may influence DXA measurements, necessitating careful interpretation by trained professionals. We present a case to show the errors that occurred during DXA analysis leading to dramatic T-score changes, highlighting the importance of technologists' adherence to manufacturers' recommendations, to ensure the accurate processing of DXA scans and diagnosis.

双能 X 射线吸收仪(DXA)是医疗诊断领域用于测量骨矿物质密度的一种精密成像技术。DXA 的意义在于它能够准确评估骨骼健康状况,这对评估骨质疏松症至关重要,骨质疏松症的特点是骨骼变弱,更容易发生骨折。尽管 DXA 被广泛采用并具有临床实用性,但它也并非没有局限性。体型、组织水化、金属植入物的存在、设备安装和维护不当以及骨密度测量方面的教育和培训不足等因素都可能影响 DXA 测量结果,因此需要训练有素的专业人员进行仔细判读。我们通过一个病例来说明在 DXA 分析过程中出现的错误导致了 T 评分的急剧变化,从而强调了技术人员遵守制造商建议的重要性,以确保准确处理 DXA 扫描和诊断。
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引用次数: 0
Pseudoarthrogram sign - a rare radiological appearance of implant failure in the knee. 假关节征象--一种罕见的膝关节植入失败的放射学表现。
IF 0.5 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-10-11 eCollection Date: 2024-09-01 DOI: 10.1093/bjrcr/uaae033
Bilal A Khan, Gorav Datta, Neeraj Purohit

We present the radiological findings in the case of a failed unicompartmental knee arthroplasty (UKA). Although uncommon, these features are highly specific for implant failure and are an indication to consider revision. The aim of this case report is to highlight these characteristic appearances across multiple imaging modalities to both surgeons and radiologists should they encounter this in their practise.

我们介绍了一例单室膝关节置换术(UKA)失败病例的放射学检查结果。这些特征虽然并不常见,但对植入失败具有高度特异性,是考虑翻修的指征。本病例报告的目的是向外科医生和放射科医生强调这些在多种成像模式下的特征性表现,以防他们在实践中遇到这种情况。
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引用次数: 0
Oesophageal injury mimicking a tubular congenital oesophageal duplication-a diagnostic dilemma: a case report. 模仿管状先天性食管重复的食管损伤--诊断难题:病例报告。
IF 0.5 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-10-03 eCollection Date: 2024-09-01 DOI: 10.1093/bjrcr/uaae035
Shreya Shrivastava, Priscilla Joshi, Shriyash Pinglikar

Intramural oesophageal dissection (IED) is an uncommon condition in newborns marked by the separation of the mucosal and submucosal layers of the oesophageal wall, both transversely and longitudinally, which may or may not involve perforation. A neonate presented at 26 h of life with poor respiratory effort and lethargy. She was intubated and was put on mechanical ventilation. Radiograph of the neonate suggested malpositioned endotracheal tube. The fluoroscopic dye-study indicated gastroesophageal oesophageal reflux disease and nothing significant. On limited CT contrast study of thorax, a tubular structure was seen running just parallel to the oesophagus extending from the T2 to the T9 levels. Possibilities of a oesophageal duplication/IED were considered. The neonate underwent an endoscopy and gastrostomy on day of life (DOL) 9. On follow up at 3 months a repeat limited CT study was done with instillation of water-soluble contrast. The previously seen tubular structure running parallel to the oesophagus was no longer seen. This finding suggested a healed IED. This case report emphasizes the significance of multimodality imaging in the diagnosis of this condition.

食管壁内剥离(IED)是新生儿中一种不常见的疾病,其特征是食管壁粘膜层和粘膜下层横向和纵向分离,可能会也可能不会涉及穿孔。一名新生儿在出生 26 小时后出现呼吸困难和嗜睡。她被插管并接受了机械通气。新生儿的 X 光片显示气管插管位置不正。透视染色检查显示她患有胃食管反流病,但无明显症状。在有限的胸部 CT 造影检查中,可以看到一个与食管平行的管状结构,从 T2 水平延伸到 T9 水平。考虑可能是食管重复/IDD。新生儿在出生后第 9 天接受了内窥镜检查和胃造口术。在 3 个月的随访中,在注入水溶性造影剂后再次进行了有限 CT 检查。之前看到的与食道平行的管状结构已不复存在。这一发现表明 IED 已经愈合。本病例报告强调了多模式成像在诊断这种疾病中的重要性。
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引用次数: 0
Intracranial vasculopathy with MR vessel wall imaging: a case series. 颅内血管病变与磁共振血管壁成像:病例系列。
IF 0.5 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-10-03 eCollection Date: 2024-09-01 DOI: 10.1093/bjrcr/uaae036
Long Hin Sin, Yat Sing Lee, Wai Tat Victor Chan, Chi Wai Siu, Chong Boon Tan

Conventional luminal imaging, often the first line investigation, has helped physicians in diagnosing countless patients with cerebrovascular disease but regrettably, it offers little diagnostic clues in patients with challenging vasculopathy, which the latter often requires invasive histopathological diagnosis. In past decade, MR vessel wall imaging has quickly emerged as a non-invasive modality that greatly enhances radiologists' capability of differentiating underlying aetiology. Not only it minimizes surgical trauma to patients, but also provide timely and accurate diagnosis for physicians to offer prompt appropriate treatment and avoid devastating outcomes. Tuen Mun Hospital, the neuroscience centre serving more than 1.3 million population in New Territories, Hong Kong, has been the pioneer in optimizing this novel modality within the district. In this article, we hope to share few interesting cases in our centre on how we utilize its advantage in solving some challenging cases. We would also discuss some common imaging pitfalls and tips on interpretation.

传统的管腔成像通常是第一线检查手段,它帮助医生诊断了无数脑血管疾病患者,但令人遗憾的是,它几乎无法为具有挑战性血管病变的患者提供诊断线索,后者通常需要侵入性组织病理学诊断。近十年来,磁共振血管壁成像作为一种无创方式迅速崛起,大大提高了放射科医生鉴别潜在病因的能力。它不仅能最大限度地减少手术对患者的创伤,还能为医生提供及时准确的诊断,以便及时提供适当的治疗,避免破坏性后果的发生。屯门医院作为香港新界130多万人口的神经科学中心,一直是区内优化这种新模式的先驱。在本文中,我们希望与大家分享本中心的几个有趣案例,介绍我们如何利用其优势解决一些具有挑战性的病例。我们还将讨论一些常见的成像误区和解读提示。
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引用次数: 0
Unusual MRI abnormality in patients with nonketotic hyperglycaemia-associated seizures. 非酮症性高血糖症相关癫痫发作患者异常的磁共振成像异常。
IF 0.5 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-09-09 eCollection Date: 2024-09-01 DOI: 10.1093/bjrcr/uaae034
Amine Bentahar, Habib Bellamlih, Khalil Chafi, Monsif Salek, Soufiane Belabbes, Brahim Zinoun, Taoufik Africha

Nonketotic hyperglycaemia (NKH) is a metabolic disorder typically observed in individuals with inadequately managed or undiagnosed diabetes mellitus (DM). Seizures are a common clinical presentation in NKH, and they tend to respond better to glucose correction than anticonvulsant therapy. MRI scans may reveal both subcortical T2/fluid-attenuated inversion recovery (FLAIR) imaging hypointensity and cortical changes, including cortical grey matter T2/FLAIR imaging hyperintensity and cortical or leptomeningeal enhancement, although cortical abnormalities are less frequently observed. These alterations are reversible when the underlying metabolic disturbance is effectively addressed. We suggest the role of iron accumulation as a mechanism for subcortical T2 hypointensity using T2* weighted imaging. Our cases substantiate the significance of subcortical T2/FLAIR hypointensity as a fundamental feature of this condition. In the appropriate clinical context, the recognition of these MRI abnormalities can help prevent misdiagnosis and facilitate timely treatment.

非酮症性高血糖(NKH)是一种代谢紊乱,通常见于糖尿病(DM)控制不当或未确诊的患者。癫痫发作是 NKH 常见的临床表现,与抗惊厥治疗相比,癫痫发作对葡萄糖纠正的反应往往更好。磁共振成像扫描可显示皮质下 T2/流体增强反转恢复(FLAIR)成像低密度和皮质改变,包括皮质灰质 T2/FLAIR 成像高密度和皮质或脑膜增强,但皮质异常较少观察到。如果能有效解决潜在的代谢紊乱,这些改变是可逆的。我们利用 T2* 加权成像技术提出,铁积聚是皮层下 T2 低密度的机制之一。我们的病例证实了皮层下 T2/FLAIR 低密度作为该病基本特征的重要性。在适当的临床情况下,识别这些 MRI 异常有助于防止误诊并促进及时治疗。
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引用次数: 0
Appendiceal intussusception due to endometriosis presenting as acute right lower quadrant pain. 子宫内膜异位症引起的阑尾肠套叠,表现为急性右下腹疼痛。
IF 0.5 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-09-04 eCollection Date: 2024-09-01 DOI: 10.1093/bjrcr/uaae032
Ahmed O El Sadaney, Ariel D Sandhu, Ahmad Parvinian, Avinash Nehra, Garima Suman

Appendiceal intussusception is a rare condition characterized by the telescoping or invagination of a portion or the entire appendix into the caecum or within the appendix itself. Diagnosing appendiceal intussusception can be challenging due to its rarity, non-specific symptoms, and lack of awareness among physicians. We present a case report of appendiceal intussusception caused by endometriosis presenting with recurrent abdominal pain in a young female that was initially missed on CT scan and laparoscopy and eventually diagnosed on CT enterography.

阑尾肠套叠是一种罕见疾病,其特征是部分或整个阑尾伸缩或内陷到盲肠或阑尾本身。由于其罕见性、非特异性症状以及医生缺乏认识,阑尾肠套叠的诊断具有挑战性。我们报告了一例年轻女性因子宫内膜异位症引起阑尾肠套叠并伴有反复腹痛的病例,该病例最初在 CT 扫描和腹腔镜检查中被漏诊,最终在 CT 肠造影检查中被确诊。
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引用次数: 0
A case of adrenal oncocytoma: reviewing the literature of radiological finding. 一例肾上腺肿瘤:回顾放射学发现的文献。
IF 0.5 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-08-30 eCollection Date: 2024-09-01 DOI: 10.1093/bjrcr/uaae029
Maho Sakano, Yukari Wakabayashi, Natsuhiko Shirota, Yoshio Ohno, Aoi Suketa, Toshitaka Nagao, Kazuhiro Saito

Oncocytoma is a tumour that predominantly occurs in the kidneys and salivary glands. Only approximately 200 cases have been reported to be of adrenal origin to date, and only a few reports about its radiological findings have been published so far. Herein, we present the CT and MRI findings of an adrenal oncocytoma observed in a patient suspected of having mitochondrial abnormalities, along with the pathological findings. The tumour was roughly classified into three areas: a hypercellular region, a region containing fibrous tissue, and an oedematous region. These corresponded to the restricted diffusion area on the apparent diffusion coefficient map, the gradually enhanced area at the secretory phase on contrast-enhanced CT scan, and the obvious hyperintensity on the T2-weighted image, respectively. We also discuss these findings in the context of previously reported radiological findings in the literature. Diagnosing adrenal oncocytoma through imaging is challenging, and it is crucial to consider the possibility of malignancy while making the differential diagnosis. Small-sized homogenous tumours may be hard to differentiate from lipid-poor adenomas, while larger inhomogeneous ones are hard to distinguish from adrenal cancer.

肿瘤细胞瘤是一种主要发生在肾脏和唾液腺的肿瘤。迄今为止,仅有约 200 例肾上腺来源的肿瘤被报道,而有关其放射学结果的报道也寥寥无几。在此,我们介绍了一名疑似线粒体异常患者肾上腺肿瘤的 CT 和 MRI 结果以及病理结果。肿瘤大致分为三个区域:高细胞区、含纤维组织区和水肿区。这些区域分别与表观扩散系数图上的扩散受限区、对比增强 CT 扫描中分泌期的逐渐增强区和 T2 加权图像上的明显高密度区相对应。我们还结合以前文献中报道的放射学结果对这些发现进行了讨论。通过影像学诊断肾上腺肿瘤细胞瘤具有挑战性,在进行鉴别诊断时考虑恶性肿瘤的可能性至关重要。体积较小的均质肿瘤可能很难与贫脂腺瘤相鉴别,而体积较大的不均质肿瘤则很难与肾上腺癌相鉴别。
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引用次数: 0
A case of MRI-induced headache caused by an intracranial foreign body. 一例由颅内异物引起的核磁共振成像诱发头痛病例。
IF 0.5 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-08-29 eCollection Date: 2024-09-01 DOI: 10.1093/bjrcr/uaae030
Hiroyuki Tokue, Azusa Tokue, Yoshito Tsushima

This case report delves into a unique occurrence of MRI-induced headaches attributed to an unsuspected intracranial foreign body. A male patient, presenting persistent headaches, experienced exacerbation of pain upon entering the MRI suite, hindering the imaging procedure. A subsequent head CT scan revealed a nail within the cranial cavity, stemming from a previous nail gun injury. Surgical removal was deemed unsafe, leading to continued observation. This case emphasizes the need for cautious exploration of abnormal symptoms in the MRI suite, urging healthcare professionals to consider potential foreign bodies. The incident underscores the risk of metallic fragments causing complications during MRI procedures and highlights the importance of thorough patient assessment before resorting to MRI imaging.

本病例报告深入探讨了一起独特的核磁共振成像诱发头痛的病例,其病因是一个未被发现的颅内异物。一名男性患者出现持续性头痛,进入核磁共振成像室后疼痛加剧,阻碍了成像过程。随后的头部 CT 扫描显示,颅腔内有一枚钉子,源于之前的射钉枪伤害。手术取出被认为不安全,因此需要继续观察。该病例强调了在核磁共振成像室中谨慎探查异常症状的必要性,敦促医护人员考虑潜在的异物。该事件强调了金属碎片在核磁共振成像过程中引起并发症的风险,并突出了在进行核磁共振成像之前对患者进行全面评估的重要性。
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引用次数: 0
A case of superior mesenteric artery stenting for small intestinal ischaemia caused by superior mesenteric artery invasion of pancreatic cancer. 一例因胰腺癌侵犯肠系膜上动脉导致小肠缺血而进行肠系膜上动脉支架植入术的病例。
IF 0.5 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2024-08-26 eCollection Date: 2024-09-01 DOI: 10.1093/bjrcr/uaae031
Hiroshi Kuwamura, Yohsuke Suyama, Yasuhiro Enjoji, Takahiro Einama, Yoji Kishi, Hiroshi Shinmoto

Superior mesenteric artery (SMA) invasion by a malignant tumour is a serious condition leading to intestinal ischaemia. Although SMA stenting has been reported to be useful for SMA dissection and stenosis caused by atherosclerotic plaque, SMA stenting for stenosis caused by malignant tumour invasion is rarely reported and uncertain. A 75-year-old woman presented intestinal ulcer and melena caused by SMA invasion of unresectable pancreatic cancer. The bare metal stent was implanted for the vessel stenosis, and a small intestinal ulcer was markedly improved after stenting. However, one and a half months after stenting the stent was occluded and a thrombectomy was performed. After thrombectomy, residual stenosis caused by tumour invasion was observed in the stent. The patient suddenly died 2 days after thrombectomy before additional covered stenting for residual stenosis. Stent implantation may be a treatment option for intestinal ischaemia caused by vessel invasion of malignant tumours. On the other hand, re-stenosis of the stent due to tumour ingrowth is a problem, and covered stenting is considered for long-term stent patency.

恶性肿瘤侵犯肠系膜上动脉(SMA)是导致肠缺血的一种严重情况。尽管有报道称 SMA 支架植入术可用于动脉粥样硬化斑块引起的 SMA 夹层和狭窄,但针对恶性肿瘤侵犯引起的 SMA 支架植入术却鲜有报道,且效果并不确定。一名 75 岁的妇女因无法切除的胰腺癌侵犯 SMA 而出现肠溃疡和腹泻。针对血管狭窄植入了裸金属支架,支架植入后小肠溃疡明显好转。然而,支架植入一个半月后出现闭塞,于是进行了血栓切除术。血栓切除术后,发现支架因肿瘤侵犯而残留狭窄。血栓切除术后 2 天,患者突然死亡,随后对残余狭窄进行了额外的覆盖支架植入术。对于恶性肿瘤侵犯血管导致的肠道缺血,支架植入可能是一种治疗选择。另一方面,由于肿瘤生长导致的支架再狭窄也是一个问题,为了保证支架的长期通畅,需要考虑覆盖支架。
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引用次数: 0
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