This case study describes a female patient in her late 70s who developed autoimmune cholangitis a year after finishing 35 cycles of pembrolizumab for the treatment of her non-small cell lung cancer. The diagnosis was initially missed and delayed; the patient's agoraphobia and the COVID-19 pandemic were noted as contributing factors.
{"title":"Delayed onset autoimmune cholangitis in a patient treated with pembrolizumab.","authors":"Joshua Newington, Daniel Patterson, Pilar Sanchez","doi":"10.1093/bjrcr/uaae040","DOIUrl":"https://doi.org/10.1093/bjrcr/uaae040","url":null,"abstract":"<p><p>This case study describes a female patient in her late 70s who developed autoimmune cholangitis a year after finishing 35 cycles of pembrolizumab for the treatment of her non-small cell lung cancer. The diagnosis was initially missed and delayed; the patient's agoraphobia and the COVID-19 pandemic were noted as contributing factors.</p>","PeriodicalId":45216,"journal":{"name":"BJR Case Reports","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11543344/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142606707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-22eCollection Date: 2024-11-01DOI: 10.1093/bjrcr/uaae038
Hongmin Xu, Medhat Sam Gabriel, Judy Rose James
Dual-energy X-ray absorptiometry (DXA) is a sophisticated imaging technique utilized in the field of medical diagnostics to measure bone mineral density. The significance of DXA lies in its ability to accurately assess bone health, which is crucial in the evaluation of osteoporosis, a condition characterized by weakened bones and heightened susceptibility to fractures. Despite its widespread adoption and clinical utility, DXA is not without limitations. Factors such as body size, tissue hydration, the presence of metal implants, improper equipment installation and maintenance, as well as inadequate education and training in bone densitometry may influence DXA measurements, necessitating careful interpretation by trained professionals. We present a case to show the errors that occurred during DXA analysis leading to dramatic T-score changes, highlighting the importance of technologists' adherence to manufacturers' recommendations, to ensure the accurate processing of DXA scans and diagnosis.
双能 X 射线吸收仪(DXA)是医疗诊断领域用于测量骨矿物质密度的一种精密成像技术。DXA 的意义在于它能够准确评估骨骼健康状况,这对评估骨质疏松症至关重要,骨质疏松症的特点是骨骼变弱,更容易发生骨折。尽管 DXA 被广泛采用并具有临床实用性,但它也并非没有局限性。体型、组织水化、金属植入物的存在、设备安装和维护不当以及骨密度测量方面的教育和培训不足等因素都可能影响 DXA 测量结果,因此需要训练有素的专业人员进行仔细判读。我们通过一个病例来说明在 DXA 分析过程中出现的错误导致了 T 评分的急剧变化,从而强调了技术人员遵守制造商建议的重要性,以确保准确处理 DXA 扫描和诊断。
{"title":"Quality assessment in bone densitometry: a case of incorrect hip analysis.","authors":"Hongmin Xu, Medhat Sam Gabriel, Judy Rose James","doi":"10.1093/bjrcr/uaae038","DOIUrl":"10.1093/bjrcr/uaae038","url":null,"abstract":"<p><p>Dual-energy X-ray absorptiometry (DXA) is a sophisticated imaging technique utilized in the field of medical diagnostics to measure bone mineral density. The significance of DXA lies in its ability to accurately assess bone health, which is crucial in the evaluation of osteoporosis, a condition characterized by weakened bones and heightened susceptibility to fractures. Despite its widespread adoption and clinical utility, DXA is not without limitations. Factors such as body size, tissue hydration, the presence of metal implants, improper equipment installation and maintenance, as well as inadequate education and training in bone densitometry may influence DXA measurements, necessitating careful interpretation by trained professionals. We present a case to show the errors that occurred during DXA analysis leading to dramatic T-score changes, highlighting the importance of technologists' adherence to manufacturers' recommendations, to ensure the accurate processing of DXA scans and diagnosis.</p>","PeriodicalId":45216,"journal":{"name":"BJR Case Reports","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2024-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11530240/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142569261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-11eCollection Date: 2024-09-01DOI: 10.1093/bjrcr/uaae033
Bilal A Khan, Gorav Datta, Neeraj Purohit
We present the radiological findings in the case of a failed unicompartmental knee arthroplasty (UKA). Although uncommon, these features are highly specific for implant failure and are an indication to consider revision. The aim of this case report is to highlight these characteristic appearances across multiple imaging modalities to both surgeons and radiologists should they encounter this in their practise.
{"title":"Pseudoarthrogram sign - a rare radiological appearance of implant failure in the knee.","authors":"Bilal A Khan, Gorav Datta, Neeraj Purohit","doi":"10.1093/bjrcr/uaae033","DOIUrl":"https://doi.org/10.1093/bjrcr/uaae033","url":null,"abstract":"<p><p>We present the radiological findings in the case of a failed unicompartmental knee arthroplasty (UKA). Although uncommon, these features are highly specific for implant failure and are an indication to consider revision. The aim of this case report is to highlight these characteristic appearances across multiple imaging modalities to both surgeons and radiologists should they encounter this in their practise.</p>","PeriodicalId":45216,"journal":{"name":"BJR Case Reports","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2024-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11474001/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142477231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Intramural oesophageal dissection (IED) is an uncommon condition in newborns marked by the separation of the mucosal and submucosal layers of the oesophageal wall, both transversely and longitudinally, which may or may not involve perforation. A neonate presented at 26 h of life with poor respiratory effort and lethargy. She was intubated and was put on mechanical ventilation. Radiograph of the neonate suggested malpositioned endotracheal tube. The fluoroscopic dye-study indicated gastroesophageal oesophageal reflux disease and nothing significant. On limited CT contrast study of thorax, a tubular structure was seen running just parallel to the oesophagus extending from the T2 to the T9 levels. Possibilities of a oesophageal duplication/IED were considered. The neonate underwent an endoscopy and gastrostomy on day of life (DOL) 9. On follow up at 3 months a repeat limited CT study was done with instillation of water-soluble contrast. The previously seen tubular structure running parallel to the oesophagus was no longer seen. This finding suggested a healed IED. This case report emphasizes the significance of multimodality imaging in the diagnosis of this condition.
{"title":"Oesophageal injury mimicking a tubular congenital oesophageal duplication-a diagnostic dilemma: a case report.","authors":"Shreya Shrivastava, Priscilla Joshi, Shriyash Pinglikar","doi":"10.1093/bjrcr/uaae035","DOIUrl":"https://doi.org/10.1093/bjrcr/uaae035","url":null,"abstract":"<p><p>Intramural oesophageal dissection (IED) is an uncommon condition in newborns marked by the separation of the mucosal and submucosal layers of the oesophageal wall, both transversely and longitudinally, which may or may not involve perforation. A neonate presented at 26 h of life with poor respiratory effort and lethargy. She was intubated and was put on mechanical ventilation. Radiograph of the neonate suggested malpositioned endotracheal tube. The fluoroscopic dye-study indicated gastroesophageal oesophageal reflux disease and nothing significant. On limited CT contrast study of thorax, a tubular structure was seen running just parallel to the oesophagus extending from the T2 to the T9 levels. Possibilities of a oesophageal duplication/IED were considered. The neonate underwent an endoscopy and gastrostomy on day of life (DOL) 9. On follow up at 3 months a repeat limited CT study was done with instillation of water-soluble contrast. The previously seen tubular structure running parallel to the oesophagus was no longer seen. This finding suggested a healed IED. This case report emphasizes the significance of multimodality imaging in the diagnosis of this condition.</p>","PeriodicalId":45216,"journal":{"name":"BJR Case Reports","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2024-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11486540/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142477230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-03eCollection Date: 2024-09-01DOI: 10.1093/bjrcr/uaae036
Long Hin Sin, Yat Sing Lee, Wai Tat Victor Chan, Chi Wai Siu, Chong Boon Tan
Conventional luminal imaging, often the first line investigation, has helped physicians in diagnosing countless patients with cerebrovascular disease but regrettably, it offers little diagnostic clues in patients with challenging vasculopathy, which the latter often requires invasive histopathological diagnosis. In past decade, MR vessel wall imaging has quickly emerged as a non-invasive modality that greatly enhances radiologists' capability of differentiating underlying aetiology. Not only it minimizes surgical trauma to patients, but also provide timely and accurate diagnosis for physicians to offer prompt appropriate treatment and avoid devastating outcomes. Tuen Mun Hospital, the neuroscience centre serving more than 1.3 million population in New Territories, Hong Kong, has been the pioneer in optimizing this novel modality within the district. In this article, we hope to share few interesting cases in our centre on how we utilize its advantage in solving some challenging cases. We would also discuss some common imaging pitfalls and tips on interpretation.
{"title":"Intracranial vasculopathy with MR vessel wall imaging: a case series.","authors":"Long Hin Sin, Yat Sing Lee, Wai Tat Victor Chan, Chi Wai Siu, Chong Boon Tan","doi":"10.1093/bjrcr/uaae036","DOIUrl":"https://doi.org/10.1093/bjrcr/uaae036","url":null,"abstract":"<p><p>Conventional luminal imaging, often the first line investigation, has helped physicians in diagnosing countless patients with cerebrovascular disease but regrettably, it offers little diagnostic clues in patients with challenging vasculopathy, which the latter often requires invasive histopathological diagnosis. In past decade, MR vessel wall imaging has quickly emerged as a non-invasive modality that greatly enhances radiologists' capability of differentiating underlying aetiology. Not only it minimizes surgical trauma to patients, but also provide timely and accurate diagnosis for physicians to offer prompt appropriate treatment and avoid devastating outcomes. Tuen Mun Hospital, the neuroscience centre serving more than 1.3 million population in New Territories, Hong Kong, has been the pioneer in optimizing this novel modality within the district. In this article, we hope to share few interesting cases in our centre on how we utilize its advantage in solving some challenging cases. We would also discuss some common imaging pitfalls and tips on interpretation.</p>","PeriodicalId":45216,"journal":{"name":"BJR Case Reports","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2024-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11483133/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142477229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nonketotic hyperglycaemia (NKH) is a metabolic disorder typically observed in individuals with inadequately managed or undiagnosed diabetes mellitus (DM). Seizures are a common clinical presentation in NKH, and they tend to respond better to glucose correction than anticonvulsant therapy. MRI scans may reveal both subcortical T2/fluid-attenuated inversion recovery (FLAIR) imaging hypointensity and cortical changes, including cortical grey matter T2/FLAIR imaging hyperintensity and cortical or leptomeningeal enhancement, although cortical abnormalities are less frequently observed. These alterations are reversible when the underlying metabolic disturbance is effectively addressed. We suggest the role of iron accumulation as a mechanism for subcortical T2 hypointensity using T2* weighted imaging. Our cases substantiate the significance of subcortical T2/FLAIR hypointensity as a fundamental feature of this condition. In the appropriate clinical context, the recognition of these MRI abnormalities can help prevent misdiagnosis and facilitate timely treatment.
{"title":"Unusual MRI abnormality in patients with nonketotic hyperglycaemia-associated seizures.","authors":"Amine Bentahar, Habib Bellamlih, Khalil Chafi, Monsif Salek, Soufiane Belabbes, Brahim Zinoun, Taoufik Africha","doi":"10.1093/bjrcr/uaae034","DOIUrl":"https://doi.org/10.1093/bjrcr/uaae034","url":null,"abstract":"<p><p>Nonketotic hyperglycaemia (NKH) is a metabolic disorder typically observed in individuals with inadequately managed or undiagnosed diabetes mellitus (DM). Seizures are a common clinical presentation in NKH, and they tend to respond better to glucose correction than anticonvulsant therapy. MRI scans may reveal both subcortical T2/fluid-attenuated inversion recovery (FLAIR) imaging hypointensity and cortical changes, including cortical grey matter T2/FLAIR imaging hyperintensity and cortical or leptomeningeal enhancement, although cortical abnormalities are less frequently observed. These alterations are reversible when the underlying metabolic disturbance is effectively addressed. We suggest the role of iron accumulation as a mechanism for subcortical T2 hypointensity using T2* weighted imaging. Our cases substantiate the significance of subcortical T2/FLAIR hypointensity as a fundamental feature of this condition. In the appropriate clinical context, the recognition of these MRI abnormalities can help prevent misdiagnosis and facilitate timely treatment.</p>","PeriodicalId":45216,"journal":{"name":"BJR Case Reports","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2024-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11412579/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142298084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-09-04eCollection Date: 2024-09-01DOI: 10.1093/bjrcr/uaae032
Ahmed O El Sadaney, Ariel D Sandhu, Ahmad Parvinian, Avinash Nehra, Garima Suman
Appendiceal intussusception is a rare condition characterized by the telescoping or invagination of a portion or the entire appendix into the caecum or within the appendix itself. Diagnosing appendiceal intussusception can be challenging due to its rarity, non-specific symptoms, and lack of awareness among physicians. We present a case report of appendiceal intussusception caused by endometriosis presenting with recurrent abdominal pain in a young female that was initially missed on CT scan and laparoscopy and eventually diagnosed on CT enterography.
{"title":"Appendiceal intussusception due to endometriosis presenting as acute right lower quadrant pain.","authors":"Ahmed O El Sadaney, Ariel D Sandhu, Ahmad Parvinian, Avinash Nehra, Garima Suman","doi":"10.1093/bjrcr/uaae032","DOIUrl":"https://doi.org/10.1093/bjrcr/uaae032","url":null,"abstract":"<p><p>Appendiceal intussusception is a rare condition characterized by the telescoping or invagination of a portion or the entire appendix into the caecum or within the appendix itself. Diagnosing appendiceal intussusception can be challenging due to its rarity, non-specific symptoms, and lack of awareness among physicians. We present a case report of appendiceal intussusception caused by endometriosis presenting with recurrent abdominal pain in a young female that was initially missed on CT scan and laparoscopy and eventually diagnosed on CT enterography.</p>","PeriodicalId":45216,"journal":{"name":"BJR Case Reports","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2024-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11387768/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142298083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Oncocytoma is a tumour that predominantly occurs in the kidneys and salivary glands. Only approximately 200 cases have been reported to be of adrenal origin to date, and only a few reports about its radiological findings have been published so far. Herein, we present the CT and MRI findings of an adrenal oncocytoma observed in a patient suspected of having mitochondrial abnormalities, along with the pathological findings. The tumour was roughly classified into three areas: a hypercellular region, a region containing fibrous tissue, and an oedematous region. These corresponded to the restricted diffusion area on the apparent diffusion coefficient map, the gradually enhanced area at the secretory phase on contrast-enhanced CT scan, and the obvious hyperintensity on the T2-weighted image, respectively. We also discuss these findings in the context of previously reported radiological findings in the literature. Diagnosing adrenal oncocytoma through imaging is challenging, and it is crucial to consider the possibility of malignancy while making the differential diagnosis. Small-sized homogenous tumours may be hard to differentiate from lipid-poor adenomas, while larger inhomogeneous ones are hard to distinguish from adrenal cancer.
{"title":"A case of adrenal oncocytoma: reviewing the literature of radiological finding.","authors":"Maho Sakano, Yukari Wakabayashi, Natsuhiko Shirota, Yoshio Ohno, Aoi Suketa, Toshitaka Nagao, Kazuhiro Saito","doi":"10.1093/bjrcr/uaae029","DOIUrl":"10.1093/bjrcr/uaae029","url":null,"abstract":"<p><p>Oncocytoma is a tumour that predominantly occurs in the kidneys and salivary glands. Only approximately 200 cases have been reported to be of adrenal origin to date, and only a few reports about its radiological findings have been published so far. Herein, we present the CT and MRI findings of an adrenal oncocytoma observed in a patient suspected of having mitochondrial abnormalities, along with the pathological findings. The tumour was roughly classified into three areas: a hypercellular region, a region containing fibrous tissue, and an oedematous region. These corresponded to the restricted diffusion area on the apparent diffusion coefficient map, the gradually enhanced area at the secretory phase on contrast-enhanced CT scan, and the obvious hyperintensity on the T2-weighted image, respectively. We also discuss these findings in the context of previously reported radiological findings in the literature. Diagnosing adrenal oncocytoma through imaging is challenging, and it is crucial to consider the possibility of malignancy while making the differential diagnosis. Small-sized homogenous tumours may be hard to differentiate from lipid-poor adenomas, while larger inhomogeneous ones are hard to distinguish from adrenal cancer.</p>","PeriodicalId":45216,"journal":{"name":"BJR Case Reports","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2024-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11377097/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142141351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-08-29eCollection Date: 2024-09-01DOI: 10.1093/bjrcr/uaae030
Hiroyuki Tokue, Azusa Tokue, Yoshito Tsushima
This case report delves into a unique occurrence of MRI-induced headaches attributed to an unsuspected intracranial foreign body. A male patient, presenting persistent headaches, experienced exacerbation of pain upon entering the MRI suite, hindering the imaging procedure. A subsequent head CT scan revealed a nail within the cranial cavity, stemming from a previous nail gun injury. Surgical removal was deemed unsafe, leading to continued observation. This case emphasizes the need for cautious exploration of abnormal symptoms in the MRI suite, urging healthcare professionals to consider potential foreign bodies. The incident underscores the risk of metallic fragments causing complications during MRI procedures and highlights the importance of thorough patient assessment before resorting to MRI imaging.
{"title":"A case of MRI-induced headache caused by an intracranial foreign body.","authors":"Hiroyuki Tokue, Azusa Tokue, Yoshito Tsushima","doi":"10.1093/bjrcr/uaae030","DOIUrl":"https://doi.org/10.1093/bjrcr/uaae030","url":null,"abstract":"<p><p>This case report delves into a unique occurrence of MRI-induced headaches attributed to an unsuspected intracranial foreign body. A male patient, presenting persistent headaches, experienced exacerbation of pain upon entering the MRI suite, hindering the imaging procedure. A subsequent head CT scan revealed a nail within the cranial cavity, stemming from a previous nail gun injury. Surgical removal was deemed unsafe, leading to continued observation. This case emphasizes the need for cautious exploration of abnormal symptoms in the MRI suite, urging healthcare professionals to consider potential foreign bodies. The incident underscores the risk of metallic fragments causing complications during MRI procedures and highlights the importance of thorough patient assessment before resorting to MRI imaging.</p>","PeriodicalId":45216,"journal":{"name":"BJR Case Reports","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2024-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11384109/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142298082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Superior mesenteric artery (SMA) invasion by a malignant tumour is a serious condition leading to intestinal ischaemia. Although SMA stenting has been reported to be useful for SMA dissection and stenosis caused by atherosclerotic plaque, SMA stenting for stenosis caused by malignant tumour invasion is rarely reported and uncertain. A 75-year-old woman presented intestinal ulcer and melena caused by SMA invasion of unresectable pancreatic cancer. The bare metal stent was implanted for the vessel stenosis, and a small intestinal ulcer was markedly improved after stenting. However, one and a half months after stenting the stent was occluded and a thrombectomy was performed. After thrombectomy, residual stenosis caused by tumour invasion was observed in the stent. The patient suddenly died 2 days after thrombectomy before additional covered stenting for residual stenosis. Stent implantation may be a treatment option for intestinal ischaemia caused by vessel invasion of malignant tumours. On the other hand, re-stenosis of the stent due to tumour ingrowth is a problem, and covered stenting is considered for long-term stent patency.
恶性肿瘤侵犯肠系膜上动脉(SMA)是导致肠缺血的一种严重情况。尽管有报道称 SMA 支架植入术可用于动脉粥样硬化斑块引起的 SMA 夹层和狭窄,但针对恶性肿瘤侵犯引起的 SMA 支架植入术却鲜有报道,且效果并不确定。一名 75 岁的妇女因无法切除的胰腺癌侵犯 SMA 而出现肠溃疡和腹泻。针对血管狭窄植入了裸金属支架,支架植入后小肠溃疡明显好转。然而,支架植入一个半月后出现闭塞,于是进行了血栓切除术。血栓切除术后,发现支架因肿瘤侵犯而残留狭窄。血栓切除术后 2 天,患者突然死亡,随后对残余狭窄进行了额外的覆盖支架植入术。对于恶性肿瘤侵犯血管导致的肠道缺血,支架植入可能是一种治疗选择。另一方面,由于肿瘤生长导致的支架再狭窄也是一个问题,为了保证支架的长期通畅,需要考虑覆盖支架。
{"title":"A case of superior mesenteric artery stenting for small intestinal ischaemia caused by superior mesenteric artery invasion of pancreatic cancer.","authors":"Hiroshi Kuwamura, Yohsuke Suyama, Yasuhiro Enjoji, Takahiro Einama, Yoji Kishi, Hiroshi Shinmoto","doi":"10.1093/bjrcr/uaae031","DOIUrl":"10.1093/bjrcr/uaae031","url":null,"abstract":"<p><p>Superior mesenteric artery (SMA) invasion by a malignant tumour is a serious condition leading to intestinal ischaemia. Although SMA stenting has been reported to be useful for SMA dissection and stenosis caused by atherosclerotic plaque, SMA stenting for stenosis caused by malignant tumour invasion is rarely reported and uncertain. A 75-year-old woman presented intestinal ulcer and melena caused by SMA invasion of unresectable pancreatic cancer. The bare metal stent was implanted for the vessel stenosis, and a small intestinal ulcer was markedly improved after stenting. However, one and a half months after stenting the stent was occluded and a thrombectomy was performed. After thrombectomy, residual stenosis caused by tumour invasion was observed in the stent. The patient suddenly died 2 days after thrombectomy before additional covered stenting for residual stenosis. Stent implantation may be a treatment option for intestinal ischaemia caused by vessel invasion of malignant tumours. On the other hand, re-stenosis of the stent due to tumour ingrowth is a problem, and covered stenting is considered for long-term stent patency.</p>","PeriodicalId":45216,"journal":{"name":"BJR Case Reports","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2024-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11368407/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142126913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}