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Application of 3D printing for customised treatment of upper limb disorders. 3D打印在上肢疾病定制治疗中的应用。
IF 0.3 Q4 SURGERY Pub Date : 2025-05-19 eCollection Date: 2025-07-01 DOI: 10.1016/j.jham.2025.100284
Saurabh Kumar Gupta, Navaneeth Holla, Satyam Suwas, Kaushik Chatterjee, Sathya Vamsi Krishna

Purpose: Three-dimensional (3D) technology is rapidly emerging as a valuable tool in the medical and healthcare industry, particularly for performing corrective osteotomies in upper limb extremities. This study involved patients with impaired upper limb function who underwent corrective osteotomies using a computer-assisted 3D surgical planning process with 3D-printed, patient-specific plates. The biomechanical performance of these 3D-printed, patient-specific plates was enhanced while maintaining crucial properties such as corrosion resistance and biocompatibility, ensuring their safety for clinical application in humans. The surgical outcomes were analyzed by visualizing bone healing, and an evaluation was conducted to assess the success of these methodologies by comparing the clinical outcomes achieved with those planned during the surgical planning phase.

Patients and methods: Eight cases involving malunions and deformities were treated using patient-specific bone plates fabricated through metal additive manufacturing. Preoperative computed tomography (CT) scans were used to generate virtual bone models for surgical planning. Normal/anatomical bone alignment was achieved by mirroring the contralateral healthy bone and projecting it onto the affective bone model. Surgical guides and patient-specific bone implants were then designed. These implants underwent an innovative cyclic heat treatment to optimize their strength and ductility for enhanced biomechanical performance.

Results: The final outcomes for the patients were assessed using functional scoring and radiographs. The 3D-printed surgical guides facilitated accurate osteotomy angulation and precise positioning of drilled holes, ensuring optimal placement of customised, mechanically enhanced bone plates. All patients demonstrated improved DASH scores and experienced reduced or no pain after healing.

Conclusions: This study demonstrates the success of personalized treatment for upper limb disorders using 3D-printed, patient-specific plates, which showed improved biomechanical performance after tailored heat treatment. This method of preparing patient-specific implants offers a safe and highly effective approach to treating malunions and deformities in the upper limbs with reduced surgical time.

目的:三维(3D)技术正在迅速成为医疗保健行业的一种有价值的工具,特别是在上肢进行矫正性截骨手术时。本研究涉及上肢功能受损的患者,这些患者使用计算机辅助的3D手术计划过程和3D打印的患者特异性钢板进行矫正截骨。这些3d打印的患者特异性板的生物力学性能得到了增强,同时保持了耐腐蚀性和生物相容性等关键特性,确保了它们在人类临床应用中的安全性。通过观察骨愈合来分析手术结果,并通过将临床结果与手术计划阶段的计划结果进行比较来评估这些方法的成功。患者和方法:采用金属增材制造技术制作患者特异性骨板治疗8例畸形畸形患者。术前计算机断层扫描(CT)扫描用于生成手术计划的虚拟骨模型。通过镜像对侧健康骨并将其投射到情感骨模型上,实现正常/解剖骨对齐。然后设计手术指南和患者特异性骨植入物。这些植入物经过创新的循环热处理,以优化其强度和延展性,提高生物力学性能。结果:通过功能评分和x线片评估患者的最终结果。3d打印的手术指南有助于准确的截骨角度和钻孔的精确定位,确保定制的、机械增强的骨板的最佳位置。所有患者均表现出DASH评分提高,愈合后疼痛减轻或无疼痛。结论:本研究证明了使用3d打印的患者特异性钢板进行上肢疾病个性化治疗的成功,经过定制热处理后,其生物力学性能得到改善。这种制备患者特异性植入物的方法为治疗上肢畸形和畸形提供了一种安全有效的方法,减少了手术时间。
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引用次数: 0
Lateral plate fixation for middle phalangeal fractures. 侧钢板内固定治疗中指骨骨折。
IF 0.3 Q4 SURGERY Pub Date : 2025-05-15 eCollection Date: 2025-07-01 DOI: 10.1016/j.jham.2025.100282
Louis Choon Kit Wong, Abby Choke, Sze Ryn Chung, Yong Chiang Kang

Plate osteosynthesis is a core modality commonly employed for rigid surgical fixation of middle phalangeal fractures. It is conventionally done via a dorsal extensor-splitting approach, which bears the risk of plate irritation and adhesion formation with the extensor apparatus that can lead to significant postoperative stiffness. While utilizing a lateral surgical approach may avoid this issue, literature on it remains scarce within the context of middle phalangeal fractures. Here, we outline our extensor-sparing technique of lateral plate fixation in middle phalangeal fractures. We demonstrate that it is a feasible and safe method for rigid surgical fixation with favorable clinical outcomes.

钢板固定术是中指骨骨折手术固定常用的核心方式。通常采用背侧伸肌分离入路,这有钢板刺激和与伸肌器械粘连的风险,可能导致术后明显僵硬。虽然采用外侧手术入路可以避免这个问题,但关于中指骨骨折的文献仍然很少。在这里,我们概述了我们在中指骨骨折的外侧钢板固定中保留伸肌腱的技术。我们证明这是一种可行且安全的手术固定方法,具有良好的临床效果。
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引用次数: 0
Epidemiology of ∗Upper Extremity Lacrosse Injuries presenting to the United States Emergency Departments during 2014-2023. 2014-2023年美国急诊科收治的上肢曲棍球损伤流行病学
IF 0.3 Q4 SURGERY Pub Date : 2025-05-12 eCollection Date: 2025-07-01 DOI: 10.1016/j.jham.2025.100281
Carter Powell, Paul Pottanat, Colin Zieminski, Dane Daley, Charles Daly
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引用次数: 0
Clinical experiences and surgical techniques of the dorsal ulnar artery perforator free flap in reconstruction of medium-sized defects of the digits. 尺背动脉穿支游离皮瓣修复手指中等缺损的临床经验及手术技巧。
IF 0.3 Q4 SURGERY Pub Date : 2025-05-12 eCollection Date: 2025-07-01 DOI: 10.1016/j.jham.2025.100279
Celestial Xin Lu Wong, Jia Lin Sophie Xie, Sreedharan Sechachalam, Jian Hao Kevin Wong, Munn Yi Tina Lee

Introduction: Our study aims to share our surgical experiences in utilising the dorsoulnar artery perforator-based (DUAP) free flap for reconstruction of medium-sized defects of the digits.

Methods: Five patients, from 2014 to 2022, all of whom sustained critical defects of the digit(s), either due to trauma or infection, underwent resurfacing with an ipsilateral DUAP free flap. The size of the defects ranged from 2.5 to 3.5 cm in width and 3.5 to 7 cm in length. The main outcomes included active range of movement, sensory recovery of the flap, and time to return to work.

Results and techniques: All five patients demonstrated favourable outcomes following reconstruction of medium-sized digital defects using the DUAP free flap. The patients were followed up for an average of 5 months postoperatively. There were no cases of partial or complete flap failure, and none of the cases required re-exploration of anastomoses. Flap neurotisation was performed in selected cases using either end-to-end or end-to-side neurorrhaphy, achieving a 2-point discrimination of up to 7 mm at 10 weeks postoperatively. All donor sites had healed well and demonstrated good final wrist range of movement, even when flaps extended into the ulnar wrist crease. Technicial refinements included adjusting the flap position to accommodate longer pedicle lengths for defects with short recipient vessels or a wider zone of injury, using a cuff of the main ulnar artery for anastomosis in cases of vessel size mismatch, and using either the dorsal digital vein or superficial dorsal hand vein to mitigate venous congestion.End-to-side (ETS) neurotization was performed in one of the cases, which allowed for preservation of thumb sensation.

Conclusion: The DUAP free flap is reliable and consistently reproducible and serves as a good option for reconstruction of medium-sized defects of the digit. It provides satisfactory functional and aesthetic outcomes, minimal donor site morbidity and the potential for sensory restoration through end-to-end and end-to-side neurotisation. Our experience supports the application of this flap beyond pulp defects, especially when selected technical modifications are employed to address the individual anatomical challenges and optimze outcomes.

Level of evidence: 4.

摘要本研究旨在分享运用背骶动脉穿支游离皮瓣修复手指中等缺损的手术经验。方法:2014年至2022年,5例因外伤或感染导致手指严重缺损的患者,均采用同侧DUAP游离皮瓣进行表面修复。缺陷的宽度为2.5 ~ 3.5 cm,长度为3.5 ~ 7 cm。主要结果包括活动范围、皮瓣感觉恢复和恢复工作时间。结果和技术:所有5例患者均表现出良好的效果,采用DUAP游离皮瓣重建中等大小的指骨缺损。术后平均随访5个月。没有皮瓣部分或完全失效的病例,没有病例需要重新探查吻合口。在选择的病例中,采用端到端或端侧神经吻合进行皮瓣神经化,在术后10周实现2点识别,最大达7毫米。所有的供体部位都愈合良好,并表现出良好的最终手腕活动范围,甚至当皮瓣延伸到尺腕皱褶。技术改进包括调整皮瓣位置,以适应较长的蒂长度缺损与较短的受体血管或较宽的损伤区,使用掌主动脉袖带吻合血管大小不匹配的情况下,并使用指背静脉或手背浅静脉减轻静脉充血。其中一例进行了端侧神经化,保留了拇指的感觉。结论:DUAP游离皮瓣可靠、重复性好,是修复手指中等缺损的良好选择。它提供了令人满意的功能和美观的结果,最小的供区发病率和潜在的感觉恢复通过端到端和端侧神经化。我们的经验支持这种皮瓣在牙髓缺损之外的应用,特别是当选择技术修改来解决个体解剖挑战和优化结果时。证据等级:4。
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引用次数: 0
Comparison of hand surgery certification exams in Europe and the United States using ChatGPT 4.0. 使用ChatGPT 4.0的欧美手外科认证考试比较
IF 0.3 Q4 SURGERY Pub Date : 2025-05-05 eCollection Date: 2025-07-01 DOI: 10.1016/j.jham.2025.100258
Salman Hasan, Kyros Ipaktchi, Nicolas Meyer, Philippe Liverneaux

Certification in hand surgery in Europe (EBHS) and the United States (HSE) requires a subspecialty examination. These exams differ in format, and practice exams, such as those published by the Journal of Hand Surgery (European Volume) and the ASSH, are used for preparation. This study aimed to compare the difficulty of the multiple-choice questions (MCQs) for the EBHS and HSE practice exams under the assumption that European MCQs are more challenging. ChatGPT 4.0 answered 94 MCQs (34 EBHS and 60 HSE practice exams) across five attempts. We excluded MCQs with visual aids. Performance was analyzed both quantitatively (overall and by section) and qualitatively. ChatGPT's scores improved after being provided with correct answers, from 59 % to 71 % for EBHS and 97 % for HSE practice exams by the 5th attempt. The European MCQs proved more difficult, with limited progress (<50 % accuracy up to the 5th attempt), while ChatGPT demonstrated better learning with the HSE questions. The complexity of the European MCQs raises questions about the harmonization of certification standards. ChatGPT can help standardize evaluations, though its performance remains inferior to that of humans. The findings confirm the hypothesis that EBHS MCQs are more challenging than the HSE practice exam.

Level of evidence: Exploratory study, level of evidence IV.

欧洲(EBHS)和美国(HSE)的手外科认证要求通过亚专科考试。这些考试的形式不同,实践考试,如手外科杂志(欧洲卷)和ASSH出版的考试,用于准备。本研究的目的是在假定欧洲的选择题难度更大的情况下,比较EBHS和HSE实践考试的选择题难度。ChatGPT 4.0在五次尝试中回答了94个mcq(34个EBHS和60个HSE实践考试)。我们排除了有视觉辅助的mcq。性能进行了定量(总体和分段)和定性分析。在提供正确答案后,ChatGPT的分数有所提高,在第5次尝试时,EBHS的分数从59%提高到71%,HSE实践考试的分数为97%。欧洲mcq更难,进展有限(证据等级:探索性研究,证据等级IV)。
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引用次数: 0
Use of compression screw in a metacarpal head Fracture: The "lollipop" technique. 掌骨头骨折加压螺钉的应用:“棒棒糖”技术。
IF 0.3 Q4 SURGERY Pub Date : 2025-05-02 eCollection Date: 2025-07-01 DOI: 10.1016/j.jham.2025.100276
Ricardo Kaempf de Oliveira, Paula Fischer, Victor Trivino, Lucian Lior Marcovici, Pedro J Delgado

Only 4 % of metacarpal fractures affect the distal articular region. In the literature, some studies have ended up causing confusion by mixing up extraarticular neck fractures with subcapital fractures, a term that should only be used to define transverse articular fractures of the head that are distal to the origin of the collateral ligament. Due to the need for anatomical reduction, displaced metacarpal head fractures must be reduced and fixed, mostly by open surgery. Recently, the use of intramedullary fixation has become the method of choice in the treatment of transverse metacarpal diaphyseal and neck fractures. Having this in mind, we describe the so-called "lollipop" technique for the treatment of subcapital metacarpal fractures, in which a cortical mini-fragment screw is inserted through the head by intramedullary retrograde fixation in the diaphysis, leaving the final assembly in the shape of the candy. By using minimal fixation, the already impaired vascularity of the head articular fragments is protected, providing enough rigid stability for the fracture to heal in an anatomical position and allowing early mobility.

只有4%的掌骨骨折影响远端关节区。在文献中,一些研究混淆了颈部关节外骨折和基底下骨折,基底下骨折仅用于定义副韧带起源远端的头部横关节骨折。由于需要解剖复位,移位的掌骨头骨折必须复位和固定,主要是通过开放手术。近年来,髓内固定已成为治疗掌骨横突及颈骨折的首选方法。考虑到这一点,我们描述了治疗掌骨下骨折的所谓“棒棒糖”技术,其中皮质微型碎片螺钉通过骨干髓内逆行固定通过头部插入,最终组装成糖果的形状。通过使用最小的固定,已经受损的头部关节碎片的血管得到保护,为骨折在解剖位置愈合提供足够的刚性稳定性,并允许早期活动。
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引用次数: 0
Rehabilitation outcomes in traumatic brachial plexus Injury: Occupational therapy perspective. 外伤性臂丛神经损伤的康复效果:职业治疗的观点。
IF 0.3 Q4 SURGERY Pub Date : 2025-05-02 eCollection Date: 2025-07-01 DOI: 10.1016/j.jham.2025.100277
Tejal Talankar, Shilpshree Palsule

Background: Traumatic Brachial Plexus Injury (TBPI) results in significant motor and sensory impairments, impacting daily function, employment, and psychological well-being. While surgical interventions aim to restore function, outcomes remain variable, necessitating comprehensive rehabilitation. Occupational Therapy (OT) plays a crucial role in optimizing upper limb function, addressing psychosocial concerns, and enhancing quality of life. However, limited research exists on its specific impact, particularly in the Indian context.

Objective: This study aimed to evaluate the functional outcomes of OT interventions in adult TBPI patients, assessing their impact on muscle strength, sensation, range of motion, functional performance, and quality of life.

Methods: A prospective longitudinal observational study was conducted at the Occupational Therapy Department of a tertiary healthcare center in Mumbai, India. 33 patients were recruited, with 31 completing the study. Functional outcomes were assessed at baseline and at 3, 6, 9, and 12 months post-intervention using muscle power assessment, sensory evaluation, range of motion, the Brachial Assessment Tool (BrAT), Disabilities of the Arm, Shoulder, and Hand (DASH) score, WHOQOL-BREF, and the Modified Mallet Score.

Results: Significant improvements were observed in muscle power (p = 0.0001), sensation (p = 0.0001). The BrAT score showed significant improvement across all time points, particularly in conservatively managed patients (p < 0.01). DASH scores demonstrated a significant reduction over 12 months (p = 0.0001), with upper plexus injuries showing better recovery than global plexus injuries. WHOQOL-BREF scores improved significantly in physical, psychological, and social domains (p < 0.05). Correlation analysis revealed a strong negative correlation between DASH and BrAT scores (R = -0.84, p = 0.0001) and a moderate positive correlation between BrAT and WHOQOL-BREF (Physical R = 0.57, Psychological R = 0.58, p = 0.0001).

Conclusion: Occupational Therapy significantly enhances functional recovery, independence in daily activities, and psychosocial well-being in TBPI patients. Conservatively managed patients showed greater functional gains compared to surgically managed patients. These findings highlight the critical role of OT in TBPI rehabilitation and the need for standardized OT protocols to improve patient outcomes.

背景:外伤性臂丛神经损伤(TBPI)会导致严重的运动和感觉障碍,影响日常功能、就业和心理健康。虽然手术干预的目的是恢复功能,但结果仍然多变,需要全面的康复。职业治疗(OT)在优化上肢功能、解决社会心理问题和提高生活质量方面起着至关重要的作用。然而,关于其具体影响的研究有限,特别是在印度的情况下。目的:本研究旨在评估OT干预对成年TBPI患者的功能结局,评估其对肌肉力量、感觉、运动范围、功能表现和生活质量的影响。方法:在印度孟买一家三级医疗保健中心的职业治疗科进行了一项前瞻性纵向观察研究,招募了33名患者,其中31名完成了研究。在基线和干预后3、6、9和12个月,使用肌肉力量评估、感觉评估、活动范围、肱评估工具(BrAT)、手臂、肩膀和手的残疾(DASH)评分、WHOQOL-BREF和改良槌球评分评估功能结果。结果:肌肉力量(p = 0.0001)、感觉(p = 0.0001)均有显著改善。BrAT评分在所有时间点都有显著改善,特别是在保守治疗的患者中(p结论:职业治疗显著提高了TBPI患者的功能恢复、日常活动的独立性和社会心理健康。与手术治疗的患者相比,保守治疗的患者表现出更大的功能改善。这些发现强调了OT在TBPI康复中的关键作用,以及标准化OT方案以改善患者预后的必要性。
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引用次数: 0
Role of five-fingered hand in type IIIB thumb hypoplasia- an Asia-Pacific perspective. 五指手在IIIB型拇指发育不全中的作用——亚太视角。
IF 0.3 Q4 SURGERY Pub Date : 2025-05-02 eCollection Date: 2025-07-01 DOI: 10.1016/j.jham.2025.100278
Anil K Bhat, Mithun Pai G, Ashwath M Acharya

The management of type IIIB thumb hypoplasia in the Asia-Pacific region is predominantly shaped by cultural views, with numerous countries favouring a five-fingered hand. The article discusses the evolution of treatment for type IIIB thumb hypoplasia with thumb preservation and reconstruction and the dilemma of excision and pollicization. Recent research has revealed the limitations of pollicization including joint instability and diminished grip strength. Moreover, several parents, particularly in the Asia-Pacific region, exhibit hesitancy towards thumb excision owing to cultural, psychological, or religious considerations, favouring the retention of a five-fingered hand. This has prompted continuous investigation into alternate techniques that preserve thumb stability while facilitating a functional five-fingered hand. Recent strategies have demonstrated encouraging outcomes comparable to conventional pollicization. In several instances, staged treatments are necessary to provide a five-fingered hand, although the reconstructed thumb may exhibit functional and developmental limits. This alternative procedure has demonstrated favourable functional and aesthetic benefits, with minimal donor morbidity, comparable to that of pollicization.

在亚太地区,IIIB型拇指发育不全的管理主要受文化观念的影响,许多国家都喜欢五指手。本文讨论了IIIB型拇指发育不全的保存和重建治疗的进展以及切除和极化的困境。最近的研究揭示了极化的局限性,包括关节不稳定和握力下降。此外,一些家长,特别是在亚太地区,由于文化、心理或宗教方面的考虑,对拇指切除表现出犹豫,倾向于保留五指手。这促使人们不断研究在保持拇指稳定性的同时促进五指手功能的替代技术。最近的战略显示出与传统的极化相当的令人鼓舞的结果。在一些情况下,分期治疗是必要的,以提供一个五个手指的手,尽管重建的拇指可能表现出功能和发育的限制。这种替代的手术已经证明了良好的功能和美学效益,与极化相比,供体发病率最低。
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引用次数: 0
Combined semi-constrained total distal radioulnar joint (DRUJ) arthroplasty and radial head arthroplasty for severe, concomitant rheumatoid disease of the wrist and elbow joints. 联合半约束全远端桡尺关节(DRUJ)和桡骨头关节成形术治疗严重伴发的腕、肘关节类风湿性疾病。
IF 0.5 Q4 SURGERY Pub Date : 2025-04-28 eCollection Date: 2025-07-01 DOI: 10.1016/j.jham.2025.100275
Zachary Fuller, Arjun Gupta, Isabel Herzog, Joseph Weisberger, Irfan H Ahmed, Michael M Vosbikian, Ashley Ignatiuk

Semi-constrained total distal radioulnar joint (DRUJ) arthroplasty with Aptis-Scheker implant has demonstrated excellent results in patients with end-stage rheumatoid arthritis (RA) of the wrist. However, clinical success of the Scheker implant in restoring range of motion may be limited in patients with concomitant degenerative disease at the proximal radioulnar joint and radiocapitellar joint, which work in tandem with the DRUJ to allow pronosupination of the forearm. Among treatment options for elbow arthritis, standalone radial head arthroplasty remains poorly studied in the context of RA, despite being used widely in trauma patients. Here, we illustrate the surgical technique for combined total DRUJ arthroplasty with a Scheker implant and radial head arthroplasty to treat long-standing, refractory RA, at the wrist and elbow joints, with excellent results at 1-year follow-up.

Aptis-Scheker假体半约束全远端桡尺关节(DRUJ)置换术在终末期类风湿性关节炎(RA)患者中显示出良好的效果。然而,在伴有近端尺桡关节和桡肱关节退行性疾病的患者中,Scheker假体恢复活动范围的临床成功可能受到限制,这两个关节与DRUJ一起工作,允许前臂旋前。在肘关节关节炎的治疗选择中,尽管在创伤患者中广泛使用,但在RA的背景下,独立桡骨头置换术的研究仍然很少。在这里,我们展示了手术技术联合全drj关节置换术与Scheker假体和桡骨头置换术治疗长期难治性RA,在腕和肘关节,在1年的随访中取得了良好的效果。
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引用次数: 0
Early postinterventional clinical implications of Collagenase Clostridium Histolyticum injection versus limited fasciectomy for Dupuytren's disease. 胶原酶溶组织梭菌注射与有限筋膜切除术治疗Dupuytren病的介入后早期临床意义
IF 0.3 Q4 SURGERY Pub Date : 2025-04-25 eCollection Date: 2025-07-01 DOI: 10.1016/j.jham.2025.100268
Rémy Liechti, Julia Bernhard, Dominique Nellie Merky, Damian Sutter, Esther Vögelin

Objectives: This study compared Collagenase Clostridium Histolyticum (CCH) injection and limited fasciectomy (LF) in terms of early post-interventional soft tissue conditions and patient burden, evaluated by visit frequency to surgeons and hand therapists, complications, and reintervention rates.

Materials and methods: Consecutive patients undergoing CCH injection or LF as first-line treatment for Dupuytren's disease over 15 years were assessed. Propensity score matching minimized selection bias. The primary outcome was the assessment of early post-interventional (between 2 and 8 weeks) soft tissue condition using a novel Soft Tissue Score with points assigned for documented swelling, hyperemia, induration, and tenderness. Secondary outcomes included the number of surgeon and hand therapy visits, as well as the complication and reintervention rates in a subgroup of patients followed for at least 4 months.

Results: After propensity score matching, two treatment groups of 26 patients each were formed (CCH vs. LF group). There were no significant differences in baseline characteristics and correction of flexion contracture between the two treatment groups. The early postinterventional Soft Tissue Score was significantly worse in the LF group than in the CCH group (mean 1.35 vs. 0.65 points, MD 0.7, 95 % CI [0.2, 1.2], p = 0.022). The number of surgeon and hand therapy visits was significantly higher in the LF group (mean 4.7 vs. 1.9 visits, MD 2.8, 95 % CI [1.8, 3.8], p < 0.001 and mean 10.5 vs. 4.3 visits, MD 6.2, 95 % CI [0.7, 11.7], p = 0.036, respectively). The rate of mild and severe complications was comparable in both groups. While the reintervention rate was significantly higher in the CCH group, the occurrence of multiple reinterventions was comparable.

Conclusion: The results of this study suggest that CCH injections lead to less complicated wound healing requiring less intensive surgeon and hand therapy aftercare than LF. CCH represents a valuable addition to Dupuytren's disease treatment, allowing for repeated use in severe, complex, or recurrent cases without increasing procedure-related risks while offering versatility for combination with minimally invasive surgery.

目的:本研究比较胶原酶溶组织梭菌(CCH)注射和有限筋膜切除术(LF)在介入后早期软组织状况和患者负担方面的差异,通过外科医生和手部治疗师的就诊频率、并发症和再干预率进行评估。材料和方法:对连续15年接受CCH注射或LF作为一线治疗Dupuytren病的患者进行评估。倾向得分匹配最小化选择偏差。主要结局是评估介入后早期(2 - 8周)的软组织状况,采用一种新的软组织评分方法,对记录的肿胀、充血、硬化和压痛进行评分。次要结果包括外科医生和手部治疗就诊次数,以及随访至少4个月的患者亚组的并发症和再干预率。结果:经倾向评分匹配后,分为CCH组和LF组,每组26例。两个治疗组在基线特征和屈曲挛缩矫正方面无显著差异。LF组介入后早期软组织评分明显低于CCH组(平均1.35分比0.65分,MD 0.7, 95% CI [0.2, 1.2], p = 0.022)。LF组的外科手术和手部治疗就诊次数显著高于LF组(平均4.7次vs. 1.9次,MD为2.8次,95% CI [1.8, 3.8], p)。结论:本研究结果表明,与LF组相比,注射CCH可减少复杂的伤口愈合,需要较少的外科手术和手部治疗后护理。CCH是Dupuytren病治疗的一个有价值的补充,允许在严重、复杂或复发的病例中重复使用,而不会增加手术相关的风险,同时提供与微创手术相结合的多功能性。
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引用次数: 0
期刊
Journal of Hand and Microsurgery
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