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Diagnostic Accuracy of Ultrasonography in Axillary Staging in Breast Cancer Patients. 超声波检查对乳腺癌患者腋窝分期的诊断准确性
IF 0.9 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2023-02-14 eCollection Date: 2023-10-01 DOI: 10.4103/jmu.jmu_99_22
Emad Mofid Nassif Rezkallah, Andrew Elsaify, Su Min Min Tin, Wael Elsaify

Background: Breast cancer is the most common malignancy affecting women all over the world and represents 7% of all cancer-related deaths in the UK. One of the most crucial elements in assessing a patient's prognosis and chance of survival with breast cancer is the condition of their axillary lymph nodes. Ultrasonography (US) is now used as a routine preoperative diagnostic tool for pretherapeutic axillary evaluation. The aim of the current study is to investigate the diagnostic accuracy of US in axillary staging in breast cancer patients.

Methods: We carried out this retrospective study for all invasive breast cancer patients who had surgery in addition to preoperative axillary staging using US during the period from January 2020 to February 2021. The final histology results were compared with the preoperative US findings to ascertain the sensitivity, specificity, positive predictive value, and negative predictive value of AUS in axillary staging.

Results: One hundred and twenty-eight patients were included in our study. The average age of diagnosis was 63.9 ± 12.3 years of age. We calculated sensitivity rate of 59.6%, specificity rate of 95.1%, positive predictive value of 87.5%, and negative predictive value of 80.2% with overall diagnostic accuracy of 82.2%.

Conclusion: Despite the important role of preoperative US in axillary staging in breast cancer patients; it failed to detect metastatic diseases in 14.8% of our patients. These findings necessitate the routine histological evaluation of the axilla for more accurate staging of the disease.

背景:乳腺癌是全世界妇女最常见的恶性肿瘤,在英国占癌症相关死亡总数的 7%。腋窝淋巴结的状况是评估乳腺癌患者预后和生存机会的最关键因素之一。目前,超声波检查(US)已成为治疗前腋窝评估的常规术前诊断工具。本研究旨在探讨 US 在乳腺癌患者腋窝分期中的诊断准确性:我们对 2020 年 1 月至 2021 年 2 月期间所有接受手术并使用 US 进行术前腋窝分期的浸润性乳腺癌患者进行了这项回顾性研究。将最终组织学结果与术前超声检查结果进行比较,以确定 AUS 在腋窝分期中的敏感性、特异性、阳性预测值和阴性预测值:我们的研究共纳入了 128 名患者。平均诊断年龄为(63.9 ± 12.3)岁。我们计算的敏感性为 59.6%,特异性为 95.1%,阳性预测值为 87.5%,阴性预测值为 80.2%,总体诊断准确率为 82.2%:结论:尽管术前 US 在乳腺癌患者的腋窝分期中发挥着重要作用,但在我们的患者中,有 14.8% 的患者未能检测出转移性疾病。因此,有必要对腋窝进行常规组织学评估,以便更准确地对疾病进行分期。
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引用次数: 0
Nora Lesion (Bizarre Parosteal Osteochondromatous Proliferation): An Ultrasound Diagnosis with Magnetic Resonance Imaging Correlation. 诺拉病变(奇异的骨膜旁骨软骨瘤增生):超声诊断与磁共振成像相关性。
IF 0.9 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2023-02-13 eCollection Date: 2023-10-01 DOI: 10.4103/jmu.jmu_53_22
Daphne J Theodorou, Stavroula J Theodorou, Yousuke Kakitsubata

Advanced cross-sectional imaging techniques are firmly established as a means of evaluating musculoskeletal disease, and ultrasound (US) is increasingly being used for the assessment of a diversity of tendon, joint, and soft-tissue abnormalities. A benign condition - bizarre parosteal osteochondromatous proliferation (BPOP) - arises from the periosteum, typically in the small bones of the hands and feet, and grows as a surface bone lesion in the surrounding soft tissue. Proliferations can become symptomatic, exercising mass effect on adjacent structures that may require operative management. As a bone-forming process, BPOP may occasionally assume worrisome histologic features that mimic sarcoma, and a pronounced tendency to recur after primary excision. A solitary mass was growing in the middle finger of a young woman that curtailed proper hand function. With US, a partially ossified formation was revealed in the proximal phalanx situated on the outer surface of the bone. There was faint acoustic shadowing distal to the lesion, and a hypoechoic halo was seen covering part of the abnormal tissue growth. Importantly, the lesion caused significant limitation of motion of the finger, on the dynamic flexion US images with the displacement of the flexor tendon and compression of a digital nerve. To restore the range of motion in the finger, surgical excision of the juxtacortical mass was performed and histology yielded a diagnosis of BPOP. We describe the US features of digital BPOP, which were found to correspond closely to those of computed tomography and magnetic resonance imaging.

先进的横断面成像技术已成为评估肌肉骨骼疾病的可靠手段,而超声波(US)也越来越多地被用于评估各种肌腱、关节和软组织异常。一种良性疾病--奇异骨膜旁骨软骨瘤增生(BPOP)--产生于骨膜,通常发生在手和脚的小骨头上,并在周围软组织中以表面骨病变的形式生长。增生可能出现症状,对邻近结构产生肿块效应,可能需要手术治疗。作为一种骨形成过程,BPOP 偶尔会出现令人担忧的组织学特征,与肉瘤相似,并且在初次切除后有明显的复发倾向。一位年轻女性的中指上长出一个单发肿块,影响了手部的正常功能。用超声检查发现,位于骨外侧的近节指骨有部分骨化形成。病变远端有微弱的声影,低回声晕覆盖了部分异常增生的组织。重要的是,病变导致手指活动明显受限,在动态屈曲 US 图像上,屈肌腱移位并压迫数字神经。为了恢复手指的活动范围,手术切除了并皮质肿块,组织学诊断为 BPOP。我们描述了数字化 BPOP 的美国特征,发现这些特征与计算机断层扫描和磁共振成像的特征非常吻合。
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引用次数: 0
Alcohol Septal Ablation for Hypertrophic Cardiomyopathy Guided by Intracoronary Myocardial Contrast Echocardiography to Reduce Myocardial Damage. 在冠状动脉内心肌对比超声心动图引导下进行肥厚型心肌病的酒精间隔消融术以减少心肌损伤
IF 1.1 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2023-02-13 eCollection Date: 2024-04-01 DOI: 10.4103/jmu.jmu_101_22
Shao-Fu Chien, Chih-Hui Chin

Septal reduction therapy (SRT) is indicated for drug-refractory hypertrophic obstructive cardiomyopathy (HOCM). SRT includes surgical myectomy and alcohol septal ablation (ASA). The outcome between SRTs are similar except complete atrioventricular (AV) block. Intracoronary myocardial contrast echocardiography is used to minimize myocardial damage by ASA. We report a case of 40-year-old male who was diagnosed of HOCM with progressed symptoms under optimal medication. Echocardiography revealed peak velocity cross left ventricular outflow tract (LVOT) 5.3 m/s, systolic anterior motion (SAM) of mitral valve with eccentric mitral regurgitation (MR) and interventricular septal thickness 16 mm. Alcohol (99.5%) 1.5 mL was injected into the first small branch of the first septal artery, under precise localization by intracoronary myocardial contrast echocardiography. The pressure gradient of apex-LVOT-aorta reduced from 90 to 20 mmHg after ASA. No AV block was noted after the procedure and echocardiography revealed improved peak velocity cross LVOT and interventricular septal thickness. No more SAM or eccentric MR was observed. Previous studies recommended ASA reserved for patients with higher surgical risk and severe comorbidities. However, a recent study showed that young adults had better long-term survival and only one-half pacemaker implantation rate than older group following ASA. Under the guidance of intracoronary myocardial contrast, target vessel could be precisely localized to small branch from a septal artery to decrease myocardial damage. Therefore, ASA may be considered as the first-line SRT for symptomatic HOCM due to minimal invasiveness and effective outcome.

室间隔减容疗法(SRT)适用于药物难治性肥厚型梗阻性心肌病(HOCM)。SRT 包括手术切除术和酒精室间隔消融术(ASA)。除完全性房室(AV)传导阻滞外,SRT 的治疗效果相似。冠状动脉内心肌显影超声心动图可最大限度地减少 ASA 对心肌的损伤。我们报告了一例 40 岁男性患者的病例,他被诊断为 HOCM,在接受最佳药物治疗后症状有所进展。超声心动图显示,左室流出道(LVOT)峰值速度为 5.3 m/s,二尖瓣收缩期前移(SAM)伴有偏心性二尖瓣反流(MR),室间隔厚度为 16 mm。在冠状动脉内心肌造影剂超声心动图的精确定位下,将 1.5 mL 酒精(99.5%)注入室间隔第一动脉的第一个小分支。ASA 术后,心尖-左心室-主动脉的压力梯度从 90 mmHg 降至 20 mmHg。术后未发现房室传导阻滞,超声心动图显示左心室出口峰值速度和室间隔厚度均有所改善。没有再观察到 SAM 或偏心 MR。以往的研究建议手术风险较高和合并症严重的患者保留使用 ASA。然而,最近的一项研究表明,与年龄较大的患者相比,年轻成人接受 ASA 后的长期生存率更高,起搏器植入率仅为后者的二分之一。在冠状动脉内心肌造影剂的引导下,可将靶血管精确定位为室间隔动脉的小分支,以减少心肌损伤。因此,ASA因其创伤小、疗效好,可被视为治疗有症状HOCM的一线SRT。
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引用次数: 0
Ultrasonographic Evaluation of Thickness and Stiffness of Achilles Tendon and Plantar Fascia in Type 2 Diabetics Patients: A Cross-sectional Observation Study. 2 型糖尿病患者跟腱和足底筋膜厚度和硬度的超声评估:横断面观察研究
IF 0.9 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2023-02-13 eCollection Date: 2023-10-01 DOI: 10.4103/jmu.jmu_109_22
Amit Saroha, Sonal Saran, Sudhir Saxena, Ravi Kant, Ajeet Singh Bhadoria

Background: Diabetes mellitus (DM) can contribute to the development of foot ulcers, a known complication of DM with a high financial and social burden. Achilles tendon (AT) and plantar fascia (PF) are well known to play an important role in foot biomechanics. The present study focuses on the alteration in thickness and stiffness of the AT and PF in Type 2 DM patients compared with the normal controls.

Methods: A cross-sectional observational study was conducted with 55 DM patients and 55 healthy volunteers as controls. The thickness of the AT and PF were measured using B-mode ultrasound and stiffness was measured using shear wave elastography. Both the thickness and stiffness in the patient group and controls were compared. The values were also compared with the clinical and demographic profiles of the patients.

Results: DM patients had considerably thicker AT and PF than controls (P < 0.05); mean values of AT thickness for DM patients and controls were 5.66 ± 0.54 mm and 4.61 ± 0.39 mm, respectively, and for PF were 2.53 ± 0.51 mm and 1.97 ± 0.19 mm, respectively. Furthermore, the stiffness of AT and PF was significantly (P < 0.05) lower in DM patients compared to controls, suggestive of softening of AT and PF in Type 2 DM patients. Mean values of shear wave velocity for DM patients and controls in AT were 5.53 ± 0.54 m/s and 7.25 ± 0.61 m/s, respectively, and for PF, 4.53 ± 0.89 m/s and 6.28 ± 0.88 m/s, respectively.

Conclusion: We conclude that there is softening and thickening of the AT and PF in Type 2 DM patients, which can impair foot biomechanics.

背景:糖尿病(DM)可导致足部溃疡的发生,足部溃疡是糖尿病的一种已知并发症,具有很高的经济和社会负担。众所周知,跟腱(AT)和足底筋膜(PF)在足部生物力学中发挥着重要作用。本研究的重点是与正常对照组相比,2 型糖尿病患者跟腱和足底筋膜厚度和硬度的变化:方法:本研究以 55 名 DM 患者和 55 名健康志愿者为对照组,进行了一项横断面观察研究。使用 B 型超声波测量 AT 和 PF 的厚度,使用剪切波弹性成像测量其硬度。对患者组和对照组的厚度和硬度进行了比较。还将这些数值与患者的临床和人口统计学特征进行了比较:DM患者的AT和PF厚度明显高于对照组(P<0.05);DM患者和对照组的AT厚度平均值分别为5.66±0.54毫米和4.61±0.39毫米,PF厚度平均值分别为2.53±0.51毫米和1.97±0.19毫米。此外,与对照组相比,DM 患者的 AT 和 PF 硬度明显降低(P < 0.05),表明 2 型糖尿病患者的 AT 和 PF 软化。DM患者和对照组的AT剪切波速度平均值分别为5.53±0.54 m/s和7.25±0.61 m/s,PF剪切波速度平均值分别为4.53±0.89 m/s和6.28±0.88 m/s:我们得出的结论是,2 型糖尿病患者的 AT 和 PF 存在软化和增厚,这会影响足部生物力学。
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引用次数: 0
Dynamic Air Bronchogram Ultrasound Sign in a Noninvasive Ventilated Patient. 无创通气患者的动态空气支气管造影超声信号。
IF 1.1 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2023-02-03 eCollection Date: 2024-04-01 DOI: 10.4103/jmu.jmu_114_22
Telmo Borges Coelho, José António Mariz

Acute dyspnea is one of the most common complaints in any emergency department. Physical examination and chest radiography have been insufficient to diagnose these patients accurately and quickly. We present a clinical case of a dyspneic patient presenting to the emergency department, who was promptly diagnosed with lobar pneumonia by point-of-care pulmonary ultrasonography. This permitted the rapid onset of adequate treatment. Furthermore, we describe a dynamic air bronchogram sign in a noninvasive ventilated patient. Chest computed tomography scan was performed confirming consolidation of the middle lobe. The advent of handheld point-of-care ultrasonography is revolutionizing practical care enabling physicians with a high-accuracy, low-cost, fast, safe, and repeatable diagnostic tool.

急性呼吸困难是急诊科最常见的主诉之一。体格检查和胸片检查都不足以准确、快速地诊断这些患者。我们介绍了一例急诊科呼吸困难患者的临床病例,该患者通过床旁肺部超声波检查被迅速诊断为大叶性肺炎。这样就能迅速开始适当的治疗。此外,我们还描述了一名无创通气患者的动态空气支气管造影征象。胸部计算机断层扫描证实了中叶的合并症。手持式护理点超声波检查的出现正在彻底改变实际的护理工作,为医生提供了一种高精度、低成本、快速、安全和可重复的诊断工具。
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引用次数: 0
Ultrasound-guided Parasagittal Infraclavicular Block for Patients without Neurostimulation Endpoints: A Case Report in Crush Injuries of the Upper Limb. 超声引导下副锁骨下阻滞治疗无神经刺激终点的患者:上肢挤压伤病例报告。
IF 1.1 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2023-01-24 eCollection Date: 2024-04-01 DOI: 10.4103/jmu.jmu_92_22
Sandeep Madhusudan Diwan, Himaunshu Vijaykumar Dongre, Ganesh Bhong, Parag Sancheti

Evoked motor responses (distal muscle responses) to a specific nerve stimulation are considered an endpoint. Often in crush injuries of the upper limb below the level of the elbow, the distal muscle responses are irrelevant. We report 14 cases of crush injuries of the upper limb that underwent an amputation below the level of the elbow. A parasagittal ultrasound-guided infraclavicular block without neurostimulation was administered in all patients. A reliable local anesthetic (LA) spread either in the perineural or perivascular area is considered adequate. Adequate intraoperative anesthesia and postoperative analgesia were achieved with the deposition of LA beneath the axillary artery.

对特定神经刺激的诱发运动反应(远端肌肉反应)被视为终点。在肘部以下的上肢挤压伤中,远端肌肉反应往往无关紧要。我们报告了 14 例在肘部水平以下截肢的上肢挤压伤病例。所有患者均在超声引导下行锁骨下阻滞,但未进行神经刺激。在神经周围或血管周围区域进行可靠的局麻药(LA)扩散即为充分。在腋动脉下方铺设局麻药可实现充分的术中麻醉和术后镇痛。
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引用次数: 0
Lemmel's Syndrome: Lesson Based on a Case Report. 莱姆梅尔综合征:基于病例报告的教训。
IF 1.1 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2023-01-19 eCollection Date: 2024-01-01 DOI: 10.4103/jmu.jmu_39_22
Renato Farina, Pietro Valerio Foti, Adriana Ilardi, Antonio Basile

Lemmel's syndrome is a bile duct disease caused by periampullary duodenal diverticula that develop within 2-3 cm of the Vater papilla. This disease manifests itself as nonobstructive jaundice. In most cases, duodenal diverticula do not cause disease, and only in a small percentage of patients, diverticula cause biliary tract obstruction by extrinsic compression. If the compression is severe, in the long term, it can become complicated with lithiasis and cholangitis. Diagnosis is very difficult, and recurrent biliary symptoms must be directly related to the compression of the duodenal diverticula. Imaging is essential for differential diagnosis and includes conventional contrast radiographs, endoscopic retrograde cholangiopancreatography, computed tomography, and magnetic resonance imaging. The investigations show the dilation of the intra- and extra-hepatic bile ducts in the absence of lithiasis or main pancreatic duct dilatation, compressed by the diverticula, which most frequently originate from the medial wall of the second duodenal tract. The treatment of choice is surgical with removal of the diverticula. Failure to diagnose can cause serious health complications for the patient.

Lemmel's 综合征是一种胆管疾病,由胰周十二指肠憩室引起,憩室发生在距 Vater 乳头 2-3 厘米的范围内。这种疾病表现为非阻塞性黄疸。在大多数情况下,十二指肠憩室不会导致疾病,只有一小部分患者的十二指肠憩室会因外源性压迫而导致胆道梗阻。如果压迫严重,长此以往会并发结石和胆管炎。诊断非常困难,反复出现的胆道症状必须与十二指肠憩室的压迫直接相关。影像学检查对鉴别诊断至关重要,包括常规造影、内镜逆行胰胆管造影、计算机断层扫描和磁共振成像。检查结果显示,在没有结石或主胰管扩张的情况下,肝内和肝外胆管扩张,受到憩室的压迫,而憩室最常见的来源是第二十二指肠道的内侧壁。首选的治疗方法是手术切除憩室。诊断失败会给患者带来严重的健康并发症。
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引用次数: 0
Congenital Bilateral Ectopic Parotid Glands: Case Report with Literature Review. 先天性双侧异位腮腺:病例报告与文献综述
IF 1.1 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2023-01-19 eCollection Date: 2024-04-01 DOI: 10.4103/jmu.jmu_85_22
Siddhi Chawla, Mohnish Bothra

Congenital ectopic bilateral parotid glands are extremely rare, to date only two cases have been reported in the literature. Our patient, a 5-day-old male, presented with bilateral palpable cheek swelling. On imaging, the absence of bilateral parotid glands in parotid space and their ectopic location, anterior to the masseter muscle, was seen. Our case emphasizes ectopic parotids as an important differential among conditions presenting with bilateral cheek swelling in children. We have also compared the findings of previously described cases and their management with our case.

先天性双侧腮腺异位极为罕见,迄今为止仅有两例文献报道。我们的患者是一名出生 5 天的男性,出现双侧腮腺肿胀。影像学检查显示,双侧腮腺在腮腺间隙中缺失,其异位位置在颌下肌前方。我们的病例强调,异位腮腺是儿童双侧颊部肿胀的重要鉴别依据。我们还将以前描述过的病例及其处理方法与我们的病例进行了比较。
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引用次数: 0
Benign Phyllodes Tumor of Axillary Tail USG and Elastography Evaluation with Histopathological Correlation. 腋尾良性蝶形瘤 USG 和弹性成像评估与组织病理学相关性研究
IF 1.1 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2023-01-17 eCollection Date: 2024-01-01 DOI: 10.4103/jmu.jmu_58_22
Gopidi Sai Nidhi Reddy, Suresh Vasant Phatak, Prashanthi Ganta, Nagendra Vadlamudi

The axillary tail, also known as spencer's tail or axillary process, is a continuation of tissue from the upper lateral quadrant of the breast that travels into the axilla through a foramen of Langer in the deep fascia. Axillary inflammation or lump is a typical clinical symptom that necessitates imaging evaluation. Since the axilla consists of lymph nodes as well as nonlymphatic tissue such as accessory breast tissue, skin, fat, muscles, nerves, and blood vessels, it has a wide variety of differential diagnoses. The radiologists should be well acquainted with axillary anatomy and imaging aspects of various axillary lesions. Here, we present a 35-year-old female with a right axillary lump which was suggestive of benign tumor on ultrasonography and was proven to be benign phyllodes tumor on histopathology.

腋窝尾,又称斯宾塞尾或腋窝突,是乳房上外侧象限组织的延续,通过深筋膜上的朗格孔进入腋窝。腋窝炎症或肿块是典型的临床症状,需要进行影像学评估。由于腋窝由淋巴结以及乳腺附属组织、皮肤、脂肪、肌肉、神经和血管等非淋巴组织组成,因此有多种鉴别诊断。放射科医生应熟知腋窝解剖和各种腋窝病变的影像学表现。本文介绍了一名 35 岁女性的右侧腋窝肿块,超声波检查提示为良性肿瘤,组织病理学检查证实为良性蝶形瘤。
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引用次数: 0
A Pediatric Right Lower Quadrant Pain Case. 小儿右下腹疼痛1例。
IF 1.1 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2023-01-01 DOI: 10.4103/JMU.JMU_41_21
Çiğdem Üner, Oğuzhan Tokur, Sonay Aydın, Fatma Dilek Gökharman
CAsE A 4-year-old male patient was admitted to the emergency department with right lower quadrant pain. On physical examination, there was tenderness and voluntary defense in the right lower quadrant. Rebound tenderness was not observed. Initially, the patient was sent for sonographic examination [Figure 1] and then to the abdominal radiography [Figure 2]. Images of the mentioned examinations are shown.
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引用次数: 0
期刊
Journal of Medical Ultrasound
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