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Update of Contrast-enhanced Ultrasound in Musculoskeletal Medicine: Clinical Perspectives - A Review. 对比增强超声在肌肉骨骼医学中的最新进展:临床观点综述。
IF 1.1 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2023-04-01 DOI: 10.4103/jmu.jmu_94_22
Shao-Yu Chen, Yao-Wei Wang, Wen-Shiang Chen, Ming-Yen Hsiao

Contrast-enhanced ultrasound (CEUS) uses an intravascular contrast agent to enhance blood flow signals and assess microcirculation in different parts of the human body. Over the past decade, CEUS has become more widely applied in musculoskeletal (MSK) medicine, and the current review aims to systematically summarize current research on the application of CEUS in the MSK field, focusing on 67 articles published between January 2001 and June 2021 in online databases including PubMed, Scopus, and Embase. CEUS has been widely used for the clinical assessment of muscle microcirculation, tendinopathy, fracture nonunions, sports-related injuries, arthritis, peripheral nerves, and tumors, and can serve as an objective and quantitative evaluation tool for prognosis and outcome prediction. Optimal CEUS parameters and diagnostic cut off values for each disease category remain to be confirmed.

对比增强超声(CEUS)使用血管内造影剂增强血流信号并评估人体不同部位的微循环。近十年来,CEUS在肌肉骨骼医学(MSK)领域的应用越来越广泛,本次综述旨在系统总结目前CEUS在MSK领域应用的研究现状,重点分析2001年1月至2021年6月在PubMed、Scopus、Embase等在线数据库中发表的67篇文章。超声造影已广泛应用于肌肉微循环、肌腱病变、骨折不愈合、运动相关损伤、关节炎、周围神经、肿瘤的临床评估,可作为客观定量的预后和预后预测的评估工具。每种疾病类别的超声造影最佳参数和诊断截止值仍有待确认。
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引用次数: 1
In Utero Treatment of Obstructive Ureterocele. 输尿管梗阻性囊肿的宫内治疗。
IF 1.1 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2023-04-01 DOI: 10.4103/jmu.jmu_8_22
Mariana Solinho, Susana Saraiva, Cátia Lourenço, Conceição Brito

Lower urinary tract obstruction consists of a heterogeneous group of conditions in which the normal urethral egress of urine from the fetal bladder is impaired. The most frequent diagnoses are posterior urethral valves, urethral atresia, and less common obstructive ureterocele. We report a case of a fetus with prenatal diagnosis of obstructive ureterocele who presented progressive bilateral hydronephrosis. A fetal cystoscopy with laser ablation was performed.

下尿路梗阻包括一组不同的情况,在这些情况下,正常的尿从胎儿膀胱的尿道出口受到损害。最常见的诊断是后尿道瓣膜、尿道闭锁和较少见的输尿管梗阻性囊肿。我们报告一个胎儿与产前诊断为输尿管梗阻性囊肿谁提出进行性双侧肾积水。采用激光消融术进行胎儿膀胱镜检查。
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引用次数: 0
Adhesions Detection and Staging Classification for Preoperative Assessment of Difficult Laparoscopic Cholecystectomies: A Prospective Case-Control Study. 腹腔镜胆囊切除术术前评估粘连检测及分期:一项前瞻性病例-对照研究。
IF 1.1 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2023-04-01 DOI: 10.4103/jmu.jmu_36_22
Atul Kapoor, Bholla Singh Sidhu, Jasdeep Singh, Navjot Brar, Paramjit Singh, Aprajita Kapur

Background: Laparoscopic cholecystectomy (LC) is the treatment of choice for cholelithiasis; however, there are procedural difficulties in determining preoperative detection of a difficult LC. The current methods using clinical and sonographic variables to identify difficult LCs have limitations to identify gallbladder adhesions which form the most common cause. We present a new method of evaluation using acoustic radiation force impulse (ARFI)-based virtual touch imaging (VTI) for the detection and classification of these patients.

Methods: Fifty consecutive patients of cholelithiasis were evaluated preoperatively using conventional scoring system (CSS) and by new adhesion detection and staging (ADS) system, and patients were classified into three classes (I-III) with class I being easy, II and III being moderate-to-high difficulty LCs. Peroperative classification was done based on the difficulty level during surgery after visualization of gallbladder adhesions. The sensitivity, specificity, and area under the curves (AUCs) of both systems were compared.

Results: Out of 50 patients, 72% and 54% of patients were in class I by CSS and ADS classification, while 28% and 46% were in class II and III, respectively, and were labeled as difficult LC cases; differences being two classifications were statistically significant (P = 0.02). Sensitivity, specificity, negative predictive value, and accuracy for ADS were 91%, 100%, 93.1%, and 96.0%, and for CSS, 60.9%, 100%, 75%, and 82% with AUCs of 1.0 and 0.63, respectively.

Conclusion: ARFI-based VTI accurately detects gallbladder adhesions and can determine the difficult cases of LCs preoperatively using ADS classification and shows higher accuracy than CSS classification, which results in lower operative time and risk of complications.

背景:腹腔镜胆囊切除术(LC)是胆石症的首选治疗方法;然而,在确定术前检测困难的LC存在程序上的困难。目前使用临床和超声变量来识别困难lc的方法在识别形成最常见原因的胆囊粘连方面存在局限性。我们提出了一种新的评估方法,使用基于声辐射力脉冲(ARFI)的虚拟触摸成像(VTI)来检测和分类这些患者。方法:对连续50例胆结石患者术前采用常规评分系统(CSS)和新型粘连检测与分期系统(ADS)进行评价,将患者分为I-III级,其中I级为易级,II级和III级为中高难度。在胆囊粘连可视化后,根据术中困难程度进行手术分型。比较两种系统的灵敏度、特异度和曲线下面积(auc)。结果:50例患者中,按照CSS和ADS分类,72%和54%的患者属于I级,28%和46%的患者属于II级和III级,并标记为LC难治性病例;两类间差异有统计学意义(P = 0.02)。ADS的敏感性、特异性、阴性预测值和准确性分别为91%、100%、93.1%和96.0%,CSS的敏感性、特异性、阴性预测值和准确性分别为60.9%、100%、75%和82%,auc分别为1.0和0.63。结论:基于arfi的VTI能准确检测胆囊粘连,术前采用ADS分类可确定胆囊粘连的疑难病例,准确率高于CSS分类,手术时间和并发症风险均较低。
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引用次数: 1
Focused Assessment with Sonography for Trauma (FAST). 创伤超声集中评估(FAST)。
IF 1.1 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2023-04-01 DOI: 10.4103/jmu.jmu_12_23
Paulo Savoia, Shri Krishna Jayanthi, Maria Cristina Chammas

The main cause of death in traumas is hypovolemic shock. Physical examination is limited to detect hemopericardium, hemoperitoneum, and hemopneumothorax. Computed tomography (CT) is the gold standard for traumatic injury evaluation. However, CT is not always available, is more expensive, and there are transportation issues, especially in hemodynamically unstable patients. In this scenario, a rapid, reproducible, portable, and noninvasive method such as ultrasound emerged, directed for detecting hemopericardium, hemoperitoneum, and hemopneumothorax, in a "point of care" modality, known as the focused assessment with sonography for trauma (FAST) protocol. With decades of experience, spread worldwide, and recommended by the most prestigious trauma care guidelines, FAST is a bedside ultrasound to be performed when accessing circulation issues of trauma patients. It is indicated to hemodynamically unstable patients with blunt abdominal trauma, with penetrating trauma of the thoracoabdominal transition (where there is doubt of penetrating the abdominal cavity) and for any patient with the cause of the instability unknown. There are four regions to be examined in the traditional FAST protocol: pericardium (to detect cardiac tamponade), right upper abdominal quadrant, left upper abdominal quadrant, and pelvis (to detect hemoperitoneum). The called extended FAST (e-FAST) protocol also searches the pleural spaces for hemothorax and pneumothorax. It is important to know the false positives and false negatives of the protocol, as well as its limitations. FAST/e-FAST protocol is designed to provide a simple "yes or no" answer regarding the presence of bleeding. It is not intended to quantify the bleeding nor evaluate organ lesions due to its limited accuracy for these purposes. Moreover, the amount of bleeding and/or the identification of organ lesions will not change patient's management: Hemodynamically unstable patients with positive FAST must go to the operating room without delay. CT should be considered for hemodynamically stable patients.

外伤死亡的主要原因是低血容量性休克。体格检查仅限于发现心包积血、腹膜积血和气胸积血。计算机断层扫描(CT)是创伤性损伤评估的金标准。然而,CT并不总是可用的,更昂贵,并且存在运输问题,特别是在血流动力学不稳定的患者中。在这种情况下,出现了一种快速、可重复、便携和无创的方法,如超声,用于检测心包积血、腹膜积血和气胸积血,这种“护理点”模式被称为创伤超声集中评估(FAST)方案。凭借数十年的经验,在世界范围内传播,并由最负盛名的创伤护理指南推荐,FAST是在访问创伤患者循环问题时进行的床边超声。它适用于血流动力学不稳定的钝性腹部创伤患者,胸腹过渡穿透性创伤(有穿透腹腔的疑问)和任何不稳定原因不明的患者。在传统的FAST方案中,有四个区域需要检查:心包(检测心包填塞)、右上腹部、左上腹部和骨盆(检测腹腔积血)。所谓的扩展FAST (e-FAST)方案也搜索胸膜间隙是否有血胸和气胸。了解该方案的假阳性和假阴性及其局限性是很重要的。FAST/e-FAST协议旨在针对是否存在出血提供简单的“是或否”答案。它不是用来量化出血或评估器官病变,因为它在这些目的上的准确性有限。此外,出血量和/或器官病变的识别不会改变患者的管理:血流动力学不稳定的FAST阳性患者必须立即前往手术室。血流动力学稳定的患者应考虑CT检查。
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引用次数: 1
Soft-Tissue Mass Lesion of the Foot - Synovial Sarcoma. 足部软组织肿块病变-滑膜肉瘤。
IF 1.1 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2023-04-01 DOI: 10.4103/JMU.JMU_22_21
Reshma Varghese, Udit Chauhan, Pranoy Paul, Sonal Saran
CAsE A 46-year-old male presented to the orthopedic outpatient clinic with a history of gradually progressive swelling and pain in the left foot for 2 years. The patient denied any history of trauma and any significant past medical or surgical history. On examination, the swelling was seen in the left foot involving the dorsal and medial aspect with tenderness on palpation. The overlying skin was stretched and showed hyperpigmentation with minimal scales and central depigmentation [Figure 1].
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引用次数: 0
Intestinal Ultrasound in Inflammatory Bowel Disease: A Novel and Increasingly Important Tool. 肠道超声诊断炎症性肠病:一种新颖且日益重要的工具。
IF 1.1 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2023-04-01 DOI: 10.4103/jmu.jmu_84_22
Wei-Chen Lin, Chen-Wang Chang, Ming-Jen Chen, Horng-Yuan Wang

New and efficacious medical therapies have become available that have greatly enhanced clinicians' ability to manage inflammatory bowel diseases (IBDs). IBD activity should be assessed regularly in scheduled examinations as the part of a treat-to-target strategy for IBD care. The gold-standard approach to investigating IBD is colonoscopy, but this is an invasive procedure. Intestinal ultrasound (IUS) has played a crucial role in recent years regarding the assessment of IBD activity because it is noninvasive, safe, reproducible, and inexpensive. IUS findings could inform changes in therapeutic interventions for IBDs; this would necessitate fewer endoscopies and enable faster decision-making processes. Furthermore, patients are accepting and tolerant of IUS examinations. This review outlines the current evidence and gives indication regarding the use of IUS in the management of IBDs.

新的和有效的医学疗法已经成为极大地提高了临床医生管理炎症性肠病(IBDs)的能力。IBD活动应在定期检查中定期评估,作为IBD治疗目标策略的一部分。调查IBD的黄金标准方法是结肠镜检查,但这是一种侵入性手术。近年来,肠道超声(IUS)由于其无创、安全、可重复性和价格低廉,在IBD活动性评估中发挥了至关重要的作用。IUS的发现可以为ibd治疗干预措施的改变提供信息;这将需要更少的内窥镜检查,并加快决策过程。此外,患者接受并耐受IUS检查。这篇综述概述了目前的证据,并给出了关于在ibd管理中使用IUS的指示。
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引用次数: 1
Does the Presence of Extended Jugular Lymphatic Sacs Add More Risk to Nuchal Thickness for Genetic and Structural Abnormality? 颈静脉淋巴囊延伸是否增加颈颈部遗传和结构异常的风险?
IF 1.1 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2023-04-01 DOI: 10.4103/jmu.jmu_225_21
Mehmet Obut, Arife Akay, Ibanoglu Can Müjde, Özge Yucel Çelik, Asya Kalayci Öncü, Zuat Acar, Erdal Seker, Erkan Saglam, Cantekin Iskender

Background: The risks added by extended jugular lymphatic sacs (EJLS) to increased nuchal translucency (NT) including genetic and structural abnormalities and pregnancy outcomes have not been previously investigated, which this study aims to investigate.

Methods: The data of 155 singleton pregnancies with increased fetal NT (≥95th percentile) of these 20 with fetal EJLS were evaluated retrospectively. Patients were stratified according to NT thickness such that ≥95th percentile - 3.5 mm, 3.6-4.4 mm, 4.5-5.4 mm, 5.5-6.4 mm, ≥6.5 mm, and grouped according to the presence of EJLS. Pregnancy outcomes, genetic and structural abnormalities were assessed by comparing EJLS with non-EJSL cases (n-EJLS).

Results: Associated with NT, the incidence of the presence of EJLS increased with NT, from 4.5% at the ≥95th percentile - 3.5 mm to 30.8% when NT ≥5.5 mm. In the n-EJLS group, the proportion of fetuses with structural and genetic abnormalities increased as the measurement of NT increased. This correlation was not observed in the EJLS group. Compared to n-EJLS, cases with EJLS had a higher rate of fetal structural (38.5% vs. 75%, P = 0.003) and genetic (18.5% vs. 45%, P = 0.005) anomalies and a lower term live birth rate (59.3% vs. 15%, P < 0.001).

Conclusion: The increasing rate of EJLS was seen as NT increased. Compared to n-EJLS, the EJLS cases had a higher rate poor pregnancy outcomes and fetal genetic and structural abnormalities.

背景:颈静脉淋巴囊(EJLS)延长对颈透明(NT)增加的风险,包括遗传和结构异常以及妊娠结局,以前没有研究过,本研究旨在探讨。方法:回顾性分析20例EJLS胎儿NT增高(≥95百分位数)的155例单胎妊娠的资料。根据NT厚度≥95个百分点- 3.5 mm、3.6-4.4 mm、4.5-5.4 mm、5.5-6.4 mm、≥6.5 mm进行分层,并根据是否存在EJLS进行分组。通过比较EJLS和非EJLS (n-EJLS)来评估妊娠结局、遗传和结构异常。结果:与NT相关,EJLS的发生率随NT的增加而增加,从≥95百分位- 3.5 mm时的4.5%增加到NT≥5.5 mm时的30.8%。在n-EJLS组中,随着NT测量的增加,结构和遗传异常的胎儿比例增加。在EJLS组中没有观察到这种相关性。与n-EJLS相比,EJLS的胎儿结构异常率(38.5%比75%,P = 0.003)和遗传异常率(18.5%比45%,P = 0.005)较高,足月活产率(59.3%比15%,P < 0.001)较低。结论:EJLS随NT的增加而增加。与n-EJLS相比,EJLS患者妊娠结局不良和胎儿遗传和结构异常的发生率更高。
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引用次数: 0
A Placental Cyst Behind the Fetal Neck in the Mid-trimester Prenatal Sonography May Mimic a Fetal Cystic Hygroma. 妊娠中期胎儿颈部后的胎盘囊肿产前超声检查可能与胎儿囊性水肿相似。
IF 1.1 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2023-04-01 DOI: 10.4103/jmu.jmu_123_22
Ching-Yu Chou, Li-Chan Lin
Subchorionic placental cysts occur in up to 5% of pregnancies, and the etiology is still controversial. Small single subchorionic placental cysts are of no clinical importance and no obstetrical management should be altered. However, a placental cyst beside the fetal neck in the mid-trimester prenatal sonography may mimic a fetal cystic hygroma that was poor prognosis. We reported a case of a placental cyst behind the fetal neck posteriorly in the mid-trimester prenatal sonography. A cyst-like lesion measured about 42 mm behind the fetal neck was detected by ultrasonography [Figure 1a]. This placental cyst was mistaken as a fetal cystic hygroma at first. However, further well examination confirmed the diagnosis of a placental cyst. At 34 gestational weeks of prenatal examination, an ultrasound revealed normal fetal growth with an intact fetal neural tube, and an independent placenta cyst was detected by transabdominal ultrasonography examination. The cyst was approximately 75 mm × 65 mm in diameter, and the intracystic echolucent area had an echodensity equivalent to that of amniotic fluid [Figure 1b and c]. Blood flow was not detected in the cystic structure on color Doppler ultrasound, and the Doppler examination of the umbilical artery revealed normal velocity and pulsatility. At 38 weeks of gestation, the woman came to our delivery room due to the onset of labor, then, a live mature female baby was delivered through vertex position through the vagina, weighting 3180 gm, body length 47 cm, with Apgar score of 9 and 9 at 1 and 5 min, respectively. A placenta cyst measured about 5cm was noted and revealed as subchorionic cyst with extravillous trophoblast cells found within the lining of the inside of the cystic wall [Figure 1d]. There were few studies showed that cases with large placental cysts with complex patterns inside the cyst. There may be an intracystic hematoma or intracystic hemorrhage.[1,2] On the other hand, because of extensive use in prenatal sonography, many fetal neck masses were noted before delivery. Therefore, A Placental Cyst Behind the Fetal Neck in the Mid‐trimester Prenatal Sonography May Mimic a Fetal Cystic Hygroma
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引用次数: 0
Breast Pseudoaneurysm in a Woman after Core Biopsy: Intravascular Glue Embolization. 乳房假性动脉瘤的妇女核心活检后:血管内胶栓塞。
IF 1.1 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2023-04-01 DOI: 10.4103/jmu.jmu_168_21
Jeong Ho Kim, Su Joa Ahn, Sang Yu Nam, Yunyeong Kim, Yong Soon Chun, Heung Kyu Park, Hye Young Choi

Core needle biopsy of breast masses is a common procedure for tissue diagnosis of breast lesions. The incidence of complications is low, with pseudoaneurysm (PA) after core biopsy has been described in the literature, and the subsequent need for surgical management. Ultrasonography is the most common modality used for not only diagnosis but also treatment of a PA. Color Doppler images show a heterogeneous echoic lesion with whirling flow inside of the lesion. We describe a patient whose breast PA that developed after core needle biopsy was successfully treated with sonographically-guided intravascular glue embolization.

乳房肿块的核心针活检是乳腺病变组织诊断的常用程序。并发症的发生率很低,文献中已经描述了核心活检后的假性动脉瘤(PA),随后需要手术治疗。超声检查是最常用的方式,不仅用于诊断,也用于治疗前列腺癌。彩色多普勒图像显示非均匀回声病变,病变内部有旋转血流。我们描述了一位患者,其乳房PA在核心针活检后发展为超声引导血管内胶栓塞成功治疗。
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引用次数: 0
A 34-Year-Old Female with Recurrent Abortions. 34岁女性,反复流产。
IF 1.1 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2023-04-01 DOI: 10.4103/jmu.jmu_101_21
Shriya Goel, Sonal Saran
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引用次数: 0
期刊
Journal of Medical Ultrasound
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