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Reshaping the agenda of the European Commission for the health systems and policy research in Europe within Horizon 2020 重塑欧盟委员会在“地平线2020”框架内的欧洲卫生系统和政策研究议程
Q3 Nursing Pub Date : 2022-07-07 DOI: 10.2427/8951
K. Walshe, M. Mckee, P. Groenewegen, J. Hansen, J. Figueras, S. Boccia, W. Ricciardi
In 2012 the European Regional Office of WHO published a new health policy strategy, Health 2020, and an accompanying European Action Plan [1, 2], with both documents since being endorsed by the 53 member states. Following consultation with member states, a series of overarching targets have been established in the three areas of Health 2020: i) reducing the burden of disease and risk factors;  ii) enhancing health and well- being; and iii) improving governance and systems for health. The WHO is now working with member state governments to develop ‘Regional’ Health 2020 targets [3, 4]. If Health 2020 is to achieve these goals, the actions that flow from it must be based on the best...
2012年,世卫组织欧洲区域办事处发布了一项新的卫生政策战略,即《健康2020》和随附的《欧洲行动计划》[1,2],这两份文件都得到了53个成员国的批准。在与会员国协商后,在《健康2020》的三个领域确立了一系列总体目标:1)减轻疾病负担和风险因素;Ii)增进健康和福祉;改善卫生治理和系统。世卫组织目前正在与成员国政府合作制定“区域”卫生2020目标[3,4]。如果《卫生2020》要实现这些目标,那么由此产生的行动必须以最佳…
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引用次数: 4
Background: cigarette smoking is the greatest known risk factor for lung cancer, and people with different smoking status may process risk information differently. While psychological distress has been linked with smoking status, little is known about the 背景:吸烟是已知的肺癌的最大危险因素,不同吸烟状况的人对风险信息的处理可能不同。虽然心理困扰与吸烟状况有关,但人们对吸烟的影响却知之甚少
Q3 Nursing Pub Date : 2022-07-07 DOI: 10.2427/8839
S. Mathur, M. Levy
Background: cigarette smoking is the greatest known risk factor for lung cancer, and people with different smoking status may process risk information differently. While psychological distress has been linked with smoking status, little is known about the impact of distress on lung cancer perception or the moderating role of physical activity and race. This study explores the association of lung cancer perception and distress and investigates the effects of physical activity and race on that association. Methods: the study uses a national, biennial survey (the Health Information National Trends Survey) that was designed to collect nationally representative data on the American public’s need for, access to, and use of cancer-related information using a cross-sectional, complex sample survey design. Out of 5 586 participants, 1 015 were current smokers, 1 599 were former smokers, 2 877 were never smokers. Of the sample, 1 765 participants answered the lung cancer risk perception question and had no personal history of lung cancer. Statistical analysis contrasts smokers, former smokers, and never smokers to examine the association of lung cancer perception and distress and the moderating role of physical activity and race. Results: distress and lung cancer risk perception were significantly positively associated (p value < 0.001). Respondents who were current smokers and were distressed had very high odds of agreeing that they have a somewhat high chance (odds ratio=900.8, CI: 94.23, 8 611.75; p value < 0.001) or a very high chance (odds ratio=500.44 CI: 56.53, 4 430.02, p value < 0.001) of developing lung cancer in the future as compared to not distressed never smokers. However, race and physical activity status did not significantly affect perception of risk. Perceptions of risk are important precursors of health change. Conclusions: elevated distress level and higher perceived risk, in addition to physical activity status and race, could potentially be used to develop targeted interventions, such as tailoring quitting support for smokers at elevated distress levels, which may enhance success rate of quitting smoking and staying quit.
背景:吸烟是已知的肺癌的最大危险因素,不同吸烟状况的人对风险信息的处理可能不同。虽然心理困扰与吸烟状况有关,但人们对焦虑对肺癌认知的影响或体育活动和种族的调节作用知之甚少。本研究探讨了肺癌认知和痛苦之间的关系,并调查了体育活动和种族对这种关系的影响。方法:该研究采用了一项两年一次的全国性调查(健康信息全国趋势调查),该调查旨在收集美国公众对癌症相关信息的需求、获取和使用的全国性代表性数据,采用了横断面复杂样本调查设计。在5586名参与者中,1015人目前是吸烟者,1599人曾经是吸烟者,2877人从不吸烟。在样本中,有1765名参与者回答了肺癌风险认知问题,并且没有个人肺癌病史。统计分析对比了吸烟者、前吸烟者和从不吸烟者,以检验肺癌认知和痛苦的关系,以及体育活动和种族的调节作用。结果:焦虑与肺癌风险认知显著正相关(p值< 0.001)。目前吸烟者和痛苦的受访者有非常高的几率同意他们有很高的机会(优势比=900.8,CI: 94.23, 8 611.75;p值< 0.001)或与不吸烟的人相比,未来患肺癌的几率非常高(优势比=500.44 CI: 56.53, 4430.02, p值< 0.001)。然而,种族和体育活动状况对风险感知没有显著影响。对风险的认识是健康变化的重要先兆。结论:除了身体活动状况和种族外,更高的痛苦水平和更高的感知风险可能被用于制定有针对性的干预措施,例如为高痛苦水平的吸烟者量身定制戒烟支持,这可能会提高戒烟成功率并保持戒烟。
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引用次数: 5
Administrative databases as a tool for identifying healthcare demand and costs in an over-one million population 管理数据库作为确定100多万人口的医疗保健需求和成本的工具
Q3 Nursing Pub Date : 2022-07-07 DOI: 10.2427/8840
F. Madotto, M. Riva, C. Fornari, L. Scalone, R. Ciampichini, C. Bonazzi, L. Mantovani, G. Cesana
Background: the aim of this study was to assess healthcare demand of specific groups of population and their costs borne by Italian Health System, using healthcare administrative databases. Methods: demographic, clinical and economic data were obtained from datasets available at the Regional Health System, combined into a data warehouse (DENALI), using a probabilistic record linkage to optimize the data matching process. The study population consisted of more than 1 million people registered in 2005 at one Local Healthcare Unit of Lombardy. Eight different segments were identified. Costs occurring in 2005 for hospital admissions, drug prescriptions, outpatient medical specialist visits were quantified in each segment. Results: healthy people accounted for 53% of the population and cost € 180 per-capita. Subjects with only one chronic disease made up 16% of the population and cost € 916 per-capita, those affected by several chronic diseases accounted for 13% and cost € 3 457 per-capita. Hospitalizations were the cost driver in five segments, ranging from 42% to 89% of total expenditures. Outpatient visits were the cost driver among healthy subjects (54%) and those with a possible chronic disease (42%), while drug costs ranged between 4% (“acute event”) and 32% (“one chronic disease”). Overall, healthcare cost was € 809 per-capita. Conclusions: healthcare costs were mainly determined by people affected by chronic conditions, even if “healthy people” ranked third for total expenditure. These costs need an appropriate identification of healthcare demand, that could be efficiently monitored through the use of administrative databases.
背景:本研究的目的是评估特定人群的医疗需求及其成本由意大利卫生系统承担,使用卫生管理数据库。方法:从区域卫生系统提供的数据集中获得人口统计、临床和经济数据,并将其合并到数据仓库(DENALI)中,使用概率记录链接来优化数据匹配过程。研究人口包括2005年在伦巴第一个地方医疗保健单位登记的100多万人。确定了八个不同的片段。2005年住院费用、药物处方费用、门诊专家诊疗费在每个部分都进行了量化。结果:健康人群占人口的53%,人均成本为180欧元。仅患有一种慢性病的受试者占人口的16%,人均费用为916欧元,患有几种慢性病的受试者占13%,人均费用为3457欧元。住院是五个部分的成本驱动因素,占总支出的42%至89%不等。门诊就诊是健康受试者(54%)和可能患有慢性疾病的受试者(42%)的成本驱动因素,而药品成本在4%(“急性事件”)和32%(“一种慢性疾病”)之间。总体而言,人均医疗保健费用为809欧元。结论:医疗保健费用主要由慢性病患者决定,即使“健康人”在总支出中排名第三。这些费用需要适当地确定医疗保健需求,这可以通过使用管理数据库进行有效监测。
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引用次数: 6
Wilks’ dissimilarity for gene clustering: computational issues 威尔克斯基因聚类的不相似性:计算问题
Q3 Nursing Pub Date : 2022-07-07 DOI: 10.2427/8761
F. M. L. D. Lascio, A. Roverato
Clustering methods are widely used in the analysis of gene expression data for their ability to uncover coordinated expression profiles. One important goal of clustering is to discover co–regulated genes because it has been postulated that co–regulation implies a similar function. In the context of agglomerative hierarchical clustering, we introduced a dissimilarity measure based on the Wilks’ Λ statistic that they called the Wilks’ dissimilarity and showed its usefulness in the identification of transcription modules. In this paper, we discuss the ability of the Wilks’ dissimilarity to identify clusters of co-expressed genes by providing an example where the most commonly used dissimilarity measures fail. Furthermore, we carry out a set of simulations aimed to investigate the use of a sparse canonical correlation technique in the estimation of the Wilks’ dissimilarity and provide guidelines for its use.
聚类方法因其揭示协调表达谱的能力而广泛应用于基因表达数据分析。聚类的一个重要目标是发现共调控基因,因为人们一直认为共调控意味着类似的功能。在聚类分层聚类的背景下,我们引入了一种基于Wilks ' Λ统计的不相似度度量,他们称之为Wilks '不相似度,并显示了其在转录模块识别中的实用性。在本文中,我们通过提供一个最常用的不相似度测量失败的例子来讨论威尔克斯不相似度识别共表达基因簇的能力。此外,我们进行了一组模拟,旨在研究稀疏典型相关技术在估计Wilks不相似性中的使用,并为其使用提供指导。
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引用次数: 0
Ernst L. Wynder: A Pioneer of No Tobacco World 恩斯特·温德:无烟世界的先驱
Q3 Nursing Pub Date : 2022-07-07 DOI: 10.2427/8918
Roberto Bucci, V. Colamesta, G. Torre
Ernst L Wynder was a great epidemiologist who devoted his career to investigate harmful effects of tobacco smoke, in particular his studies represent a landmark in the history of epidemiological research on lung cancer. The commitment of Ernst Wynder was not limited to the risk factors related to tobacco. In fact, he studied also the role of nutritional factors in the incidence of tumors. His talent, enthusiasm and tireless energy have allowed him to obtain a complete victory despite the difficulties and the initial loneliness.
恩斯特·温德是一位伟大的流行病学家,他的职业生涯致力于研究烟草烟雾的有害影响,特别是他的研究在肺癌流行病学研究史上具有里程碑意义。恩斯特温德的承诺并不局限于与烟草有关的风险因素。事实上,他还研究了营养因素在肿瘤发病率中的作用。他的才华、热情和不知疲倦的精力使他在困难和最初的孤独中获得了彻底的胜利。
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引用次数: 1
The Gini Test for Survival Data in Presence of Small and Unbalanced Groups 小群体和不平衡群体生存数据的基尼系数检验
Q3 Nursing Pub Date : 2022-07-07 DOI: 10.2427/8762
C. Gigliarano, M. Bonetti
The aim of this note is to study the performance of the Gini concentration test for survival data in presence of unbalanced and small samples. We compared the performance of the asymptotic test with an alternative permutation distribution test, illustrating by simulation that if groups are very small the latter test should be used. Also, we show how the definition of the length of time considered in the construction of the test statistic can be chosen to improve the performance of the test.
本文的目的是研究在存在不平衡和小样本的情况下,生存数据的基尼浓度检验的性能。我们比较了渐近检验与替代排列分布检验的性能,通过模拟说明,如果群体非常小,则应使用后一种检验。此外,我们还展示了如何选择在构建检验统计量时所考虑的时间长度的定义来提高检验的性能。
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引用次数: 2
Digit preference in Nigerian censuses data of 1991 and 2006 1991年和2006年尼日利亚人口普查数据中的数字偏好
Q3 Nursing Pub Date : 2022-07-07 DOI: 10.2427/8843
T. Dahiru, H. Dikko
Background: censuses in developing countries are prone to errors of age misreporting due to ignorance, low literacy levels and other social, economic and cultural factors. Ages are commonly rounded with great affinity for 0 or 5. This tendency to digit preference and/or avoidance results in age heaping or concentration of ages at certain digits. This study examined the extent of digit preference in the Nigerian census data of 1991 and 2006. Methods: this study utilized age data from the 1991 and 2006 Nigerian censuses reported in single years. The Whipple and Myers indices were used to determine the extent of digit preference. Results: both the 1991 and 2006 census data showed the expected pattern of errors, with Whipple and Myers indices being beyond acceptable levels. The Whipple index for 1991 and 2006 was 293 and 251 respectively, while the Myers index was 62.3 and 67.1 respectively. There was a strong preference for terminal digits 0 and 5, followed by 8 whereas terminal digits 1 and 9 were strongly avoided. Conclusions: the quality of age data in Nigerian census data is poor as a result of misreporting and no significant improvement or difference was observed between 1991 and 2006 censuses.
背景:由于无知、识字率低以及其他社会、经济和文化因素,发展中国家的人口普查容易出现年龄误报错误。年龄通常四舍五入,与0或5有很大的关系。这种手指偏好和/或回避的倾向导致年龄堆积或年龄集中在某些手指。本研究考察了1991年和2006年尼日利亚人口普查数据中数字偏好的程度。方法:本研究利用1991年和2006年尼日利亚人口普查的年龄数据。惠普尔和迈尔斯指数被用来确定数字偏好的程度。结果:1991年和2006年人口普查数据均呈现预期的误差模式,惠普尔指数和迈尔斯指数均超出可接受水平。1991年和2006年的惠普尔指数分别为293和251,Myers指数分别为62.3和67.1。人们对终端数字0和5有强烈的偏好,其次是8,而终端数字1和9则被强烈避免。结论:由于误报,尼日利亚人口普查数据中的年龄数据质量较差,1991年和2006年的人口普查没有显著改善或差异。
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引用次数: 3
Prevalence and effect of schistosome and soil-transmitted helminth infection on labour input in rice-growing communities of Ogun State, Nigeria 尼日利亚奥贡州水稻种植社区血吸虫和土壤传播蠕虫感染的流行及其对劳动力投入的影响
Q3 Nursing Pub Date : 2022-07-07 DOI: 10.2427/8841
S. O. Sam-Wobo, O. Akintola, J. Atungwu, U. Ekpo, Monsuru A. Adeleke, C. Mafiana
Schistosomiasis and soil-transmitted helminthiasis (STH) are public health problems in communities which lack basic social amenities with poor hygienic conditions. Studies were carried out to determine the prevalence and effect of schistosomes and soil-transmitted helminths infection on labour input on rice production in 9 rice-growing communities of Ogun State. Parasitological examinations of urine and faecal samples, and structured questionnaires were conducted on 243 consented individuals from May 2009 to March 2010. The results showed an overall prevalence of 17% for Ascaris lumbricoides, 12% for hookworms, 2% for Trichuris trichiura, 1% for Schistosoma haematobium and 1% for Schistosoma mansoni. A. lumbricoides and hookworms were more prevalent in Agbajege (25%), and varied in the other 8 communities. T. trichiura was prevalent in three communities, Agbajege (5%), Akodu (4.2%), and Moloko-Asipa (4.8 %); S. haematobium was prevalent only in Ayedere (2.6%) and Lufoko (8%), while S. mansoni was prevalent only in Moloko-Asipa (9.5%). Infections among the gender were varied as 26.3 % of males and 33.8 % of females had an overall prevalence of: A. lumbricoides (16.8%), hookworms (11.8%), T. trichiura (1.6%), S. haematobium (1.1%) and S. mansoni (1.1%). On frequency of infection to incapacitation per year, 45% of respondents were incapacitated 1-2 times, 27% 3-4 times and 19% were incapacitated more than 4 times. Understanding the effect of these two diseases will not only improve the health status of residents but also increase their productivity and ensure food security.
血吸虫病和土壤传播的蠕虫病是缺乏基本社会设施和卫生条件差的社区的公共卫生问题。在奥贡州9个水稻种植社区开展了研究,以确定血吸虫和土壤传播蠕虫感染的流行情况及其对水稻生产劳动力投入的影响。2009年5月至2010年3月,对243名自愿接受调查的人进行了尿液和粪便的寄生虫学检查和结构化问卷调查。结果显示,虫蛔虫总流行率为17%,钩虫总流行率为12%,毛滴虫总流行率为2%,血血吸虫总流行率为1%,曼氏血吸虫总流行率为1%。阿巴杰格区以蚓类和钩虫居多(25%),其他8个群落差异较大。3个社区分别为Agbajege(5%)、Akodu(4.2%)和Moloko-Asipa (4.8%);haematobium S.仅在Ayedere(2.6%)和Lufoko(8%)流行,mansoni S.仅在Moloko-Asipa(9.5%)流行。男女感染率差异较大,男性感染率为26.3%,女性感染率为33.8%,总体感染率分别为:蚓状拟虫(16.8%)、钩虫(11.8%)、毛螺旋体(1.6%)、血丝虫(1.1%)和曼氏拟虫(1.1%)。在每年感染导致丧失行为能力的频率方面,45%的应答者丧失行为能力1-2次,27%的应答者丧失行为能力3-4次,19%的应答者丧失行为能力4次以上。了解这两种疾病的影响不仅可以改善居民的健康状况,还可以提高他们的生产力,确保粮食安全。
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引用次数: 2
Open Access, impact and quality: an even harder future for gatekeepers? 开放获取、影响和质量:看门人的未来更加艰难?
Q3 Nursing Pub Date : 2022-07-07 DOI: 10.2427/8953
F. Turone
With the advent of open access publishing, coupled with easy electronic access to journals, many of the historical constraints towards access to the litterature – both as an author and as a reader – have recently been reshaped, and are still changing, raising among others issues about the quality of what is published. Many aspects are being looked at very carefully, but so far the role of the media has only occasionally been investigated. On one side, more and more scholars oppose the current use of...
随着开放获取出版的出现,再加上期刊的便捷电子获取,对文学作品获取的许多历史限制——无论是作为作者还是作为读者——最近都被重塑了,而且仍在改变,这引发了关于出版质量的其他问题。许多方面都得到了非常仔细的研究,但到目前为止,媒体的作用只是偶尔得到调查。一方面,越来越多的学者反对目前使用……
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引用次数: 1
Charles Everett Koop: the “Family doctor of America” 查尔斯·埃弗雷特·库普:“美国家庭医生”
Q3 Nursing Pub Date : 2022-07-06 DOI: 10.2427/9046
Roberto Bucci, V. Colamesta, G. Torre
Charles Everett Koop was a great Surgeon General, probably the most influential in the history of the United States of America. He never missed courage in his life and often he had used it to tackle professional and personal tough problems. In his public activity, he faced controversial health problems of American people as smoking, abortion and the first occurrence of the epidemic Acquired Immune Deficiency Syndrome (AIDS). Koop was a rigorous man. The lodestar that guided Koop in his work, as a public servant was to do the best for health of Americans. In his prestigious and difficult role, he faced the pressing problems of health of millions of people trying to avoid political influence. During his mandate of eight years, Koop increased the influence and authority of his role. His appearance and behaviour were unmistakable: Lincolnesque beard and uniform, conduct hard and pure, exclusively oriented to the health of citizens, over the personal conveniences, political pressure and lobbying. An exemplary man, who for his passion for medicine and his sincere interest in promoting public health, was affectionately considered the "Family Doctor of America".
查尔斯·埃弗雷特·库普是一位伟大的卫生局局长,可能是美国历史上最有影响力的人。在他的一生中,他从未错过勇气,他经常用它来解决职业和个人的棘手问题。在他的公共活动中,他面对了美国人民有争议的健康问题,如吸烟、堕胎和艾滋病的首次出现。库普是个严谨的人。作为一名公务员,指导库普工作的方向是为美国人的健康尽最大努力。在他享有声望和困难的角色中,他面对着数百万人的紧迫健康问题,试图避免政治影响。在他的八年任期内,库普增加了他的影响力和权威。他的外表和行为毫无疑问是:林肯式的胡子和制服,行为严谨而纯洁,完全以公民的健康为导向,而不是个人便利,政治压力和游说。他对医学的热爱和对促进公众健康的真诚兴趣,是一个模范人物,被亲切地称为“美国家庭医生”。
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引用次数: 0
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Epidemiology Biostatistics and Public Health
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