首页 > 最新文献

Epidemiology Biostatistics and Public Health最新文献

英文 中文
The Number Needed to Inform - What we talk about when we talk of science journalism 当我们谈论科学新闻时,我们谈论的是什么
Q3 Nursing Pub Date : 2022-07-08 DOI: 10.2427/8816
F. Turone
The role and the quality of science journalism – and particularly health journalism – are often debated in peer-reviewed research, along with their direct and indirect consequences on science, science policy, the public understanding of science and of course public health. Researchers have been trying to apply their methods to a discipline which differs very much from their own, for instance proposing an evaluation grid similar to...
科学新闻——尤其是健康新闻——的作用和质量,以及它们对科学、科学政策、公众对科学的理解,当然还有公共卫生的直接和间接影响,经常在同行评议的研究中受到争论。研究人员一直在尝试将他们的方法应用于一个与他们自己的学科非常不同的学科,例如提出一个类似于……
{"title":"The Number Needed to Inform - What we talk about when we talk of science journalism","authors":"F. Turone","doi":"10.2427/8816","DOIUrl":"https://doi.org/10.2427/8816","url":null,"abstract":"The role and the quality of science journalism – and particularly health journalism – are often debated in peer-reviewed research, along with their direct and indirect consequences on science, science policy, the public understanding of science and of course public health. Researchers have been trying to apply their methods to a discipline which differs very much from their own, for instance proposing an evaluation grid similar to...","PeriodicalId":45811,"journal":{"name":"Epidemiology Biostatistics and Public Health","volume":"31 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75568862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Surveillance of healthcare acquired infections in hospital and community: a retrospective study in Local Healthcare Organization of Rovigo 医院和社区卫生保健获得性感染监测:罗维戈当地卫生保健机构的回顾性研究
Q3 Nursing Pub Date : 2022-07-08 DOI: 10.2427/8747
Francesca Ronzani, M. Scarin, Marco Brusaferro, A. Intenti, Raffaela Marchetto, M. Boldrin, S. Pierotti, A. Marcolongo
Background: antimicrobial resistance is recognized as one of the greatest threats to human health worldwide. Infections caused by multidrug-resistant bacteria are associated with higher incidences of mortality, morbidity, prolonged hospital stay and increase of costs. Surveillance of alert organism/conditions and bacterial resistance to antimicrobials is a systematic and dynamic system of data collection that analyses and monitors trends of bacterial resistance. This study was conducted to detect antimicrobial susceptibility patterns in order to inform treatment choices and generate hospital-wide baseline data. Methods: the Local Healtcare Oganization of Rovigo has started a program of surveillance on antimicrobial resistance in hospital and community. In this work some results of the surveillance of microorganism isolated and related antimicrobial resistance are reported, collected in the period 2009-2010 in Rovigo and Trecenta Hospitals, Territorial Nursing Homes (TNH) and community from patients’ blood, urine and respiratory samples. Results: data show a significant difference in the level of antibiotic resistance between the two Hospitals. High rates of extended-spectrum β-lactamase (ESBL)-producing organisms are detected and carbapenems are the only reliable agents for the treatment of many infections in the Hospital of Trecenta and TNH. Conclusions: because ESBL producing bacteria are emerging pathogens in the community, the rational use of available antibiotics or the appropriate antimicrobial prescribing are imperative. Local surveillance is a powerful tool to detect and monitor hospital and community infections and provides information useful as a guide to medical practice, including therapeutics and disease-control activities.
背景:抗微生物药物耐药性被认为是全世界人类健康面临的最大威胁之一。耐多药细菌引起的感染与死亡率、发病率、住院时间延长和费用增加有关。警戒生物体/条件和细菌对抗菌素耐药性监测是一个系统和动态的数据收集系统,用于分析和监测细菌耐药性趋势。本研究旨在检测抗菌药物敏感性模式,以便为治疗选择提供信息并生成全院范围的基线数据。方法:罗维戈地方卫生组织启动了医院和社区抗菌素耐药性监测项目。本文报道了2009-2010年在罗维戈和特伦塔医院、地区疗养院(TNH)和社区收集的患者血液、尿液和呼吸道样本中分离的微生物和相关抗菌素耐药性的监测结果。结果:数据显示两家医院的抗生素耐药水平有显著差异。检测到广谱β-内酰胺酶(ESBL)产生生物的高比例,碳青霉烯类药物是治疗特伦塔医院和TNH许多感染的唯一可靠药物。结论:由于产生ESBL的细菌是社区新出现的病原体,合理使用现有抗生素或适当使用抗菌药物势在必行。地方监测是发现和监测医院和社区感染的有力工具,并提供可作为医疗实践指南的有用信息,包括治疗和疾病控制活动。
{"title":"Surveillance of healthcare acquired infections in hospital and community: a retrospective study in Local Healthcare Organization of Rovigo","authors":"Francesca Ronzani, M. Scarin, Marco Brusaferro, A. Intenti, Raffaela Marchetto, M. Boldrin, S. Pierotti, A. Marcolongo","doi":"10.2427/8747","DOIUrl":"https://doi.org/10.2427/8747","url":null,"abstract":"\u0000Background: antimicrobial resistance is recognized as one of the greatest threats to human health worldwide. Infections caused by multidrug-resistant bacteria are associated with higher incidences of mortality, morbidity, prolonged hospital stay and increase of costs. Surveillance of alert organism/conditions and bacterial resistance to antimicrobials is a systematic and dynamic system of data collection that analyses and monitors trends of bacterial resistance. This study was conducted to detect antimicrobial susceptibility patterns in order to inform treatment choices and generate hospital-wide baseline data. \u0000Methods: the Local Healtcare Oganization of Rovigo has started a program of surveillance on antimicrobial resistance in hospital and community. In this work some results of the surveillance of microorganism isolated and related antimicrobial resistance are reported, collected in the period 2009-2010 in Rovigo and Trecenta Hospitals, Territorial Nursing Homes (TNH) and community from patients’ blood, urine and respiratory samples. \u0000Results: data show a significant difference in the level of antibiotic resistance between the two Hospitals. High rates of extended-spectrum β-lactamase (ESBL)-producing organisms are detected and carbapenems are the only reliable agents for the treatment of many infections in the Hospital of Trecenta and TNH. \u0000Conclusions: because ESBL producing bacteria are emerging pathogens in the community, the rational use of available antibiotics or the appropriate antimicrobial prescribing are imperative. Local surveillance is a powerful tool to detect and monitor hospital and community infections and provides information useful as a guide to medical practice, including therapeutics and disease-control activities. \u0000","PeriodicalId":45811,"journal":{"name":"Epidemiology Biostatistics and Public Health","volume":"216 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74713002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Robert J. Levine: a distinguished problem solver 罗伯特·j·莱文:一位杰出的问题解决者
Q3 Nursing Pub Date : 2022-07-08 DOI: 10.2427/8815
Roberto Bucci, S. Traglia
Robert Levine: a man capable of intelligent and constructive criticism, who could accept with humility the criticisms of others. A man who left a deep mark in the history of research, both inside and outside the United States. Above all, a great problem solver. A brilliant doctor and refined bioethicist, he was able to deal with the disasters of research on human subjects and to remedy to them. He fought against the application in clinical practice of ethical principles valid only for research, but also against the universalisation of the rules of informed consent, which are applicable only to Western cultures. A researcher who deserves to be known by all, especially by young people.
罗伯特·莱文:一个能够提出明智和建设性批评的人,他能谦卑地接受别人的批评。他在美国国内外的研究史上都留下了深刻的印记。最重要的是,他是一个出色的问题解决者。作为一名杰出的医生和精进的生物伦理学家,他能够处理人类研究的灾难并进行补救。他反对将仅对研究有效的伦理原则应用于临床实践,但也反对将仅适用于西方文化的知情同意规则普遍化。一位值得被所有人,尤其是年轻人所熟知的研究者。
{"title":"Robert J. Levine: a distinguished problem solver","authors":"Roberto Bucci, S. Traglia","doi":"10.2427/8815","DOIUrl":"https://doi.org/10.2427/8815","url":null,"abstract":"\u0000Robert Levine: a man capable of intelligent and constructive criticism, who could accept with humility the criticisms of others. A man who left a deep mark in the history of research, both inside and outside the United States. Above all, a great problem solver. \u0000A brilliant doctor and refined bioethicist, he was able to deal with the disasters of research on human subjects and to remedy to them. He fought against the application in clinical practice of ethical principles valid only for research, but also against the universalisation of the rules of informed consent, which are applicable only to Western cultures. A researcher who deserves to be known by all, especially by young people. \u0000","PeriodicalId":45811,"journal":{"name":"Epidemiology Biostatistics and Public Health","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85904181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An Introduction to RP-Testing rp测试简介
Q3 Nursing Pub Date : 2022-07-08 DOI: 10.2427/8756
L. De Capitani
This paper reviews the concept of Reproducibility Probability and makes a brief introduction to RP-testing. The RP-based version of some common parametric tests is provided. Moreover, a particular attention is devoted to the well-known nonparametric Wilcoxon Rank-Sum test. A comparison between the properties of the RP and the p-value is made in order to evaluate the practical utility of these stability indicators. It turns out that the use of the RP to perform the tests and to interpret their results, requires more technical analysis, but it provides more interpretable direct information on the stability of the test results.
本文综述了再现性概率的概念,并对rp检验进行了简要介绍。提供了一些常见参数测试的基于rp的版本。此外,还特别关注了著名的非参数Wilcoxon秩和检验。为了评价这些稳定性指标的实际效用,对RP和p值的性质进行了比较。事实证明,使用RP来执行测试并解释其结果需要更多的技术分析,但它提供了关于测试结果稳定性的更多可解释的直接信息。
{"title":"An Introduction to RP-Testing","authors":"L. De Capitani","doi":"10.2427/8756","DOIUrl":"https://doi.org/10.2427/8756","url":null,"abstract":"This paper reviews the concept of Reproducibility Probability and makes a brief introduction to RP-testing. The RP-based version of some common parametric tests is provided. Moreover, a particular attention is devoted to the well-known nonparametric Wilcoxon Rank-Sum test. A comparison between the properties of the RP and the p-value is made in order to evaluate the practical utility of these stability indicators. It turns out that the use of the RP to perform the tests and to interpret their results, requires more technical analysis, but it provides more interpretable direct information on the stability of the test results.","PeriodicalId":45811,"journal":{"name":"Epidemiology Biostatistics and Public Health","volume":"144 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80407873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Anthropometric predictors of dyslipidemia among adults in Saudi Arabia 沙特阿拉伯成人血脂异常的人体测量预测指标
Q3 Nursing Pub Date : 2022-07-08 DOI: 10.2427/8733
Abdalla A Saeed
Background: dyslipidemia and obesity are key independent modifiable risk factors for many non communicable chronic diseases. Patterns of association between these factors may help prevention and control. This study aims to assess the association between lipids profile and obesity among adults in Kingdom of Saudi Arabia and identify anthropometric predictors of dyslipidemia. Methods: data were collected and analyzed from a cross-sectional study using WHO STEPwise approach that included 4 990 Saudi adults aged 15- 64 years selected by stratified, multistage, cluster random sampling technique. Lipid profiles (cholesterol categories and triglycerides) were determined spectrophotometrically by colorimetric biochemical methods. Obesity was determined by calculation of body mass index (BMI=Kg/m2), waist and hip circumferences and ratio and waist to height ratio. Results: the overall prevalence of obesity ranged from 33.8 to 44.4 % and the overall dyslipidemia prevalence ranged from about 25 to 44% depending on type of dyslipidemia and anthropometrics used. Prevalence of dyslipidemia and mean concentration of lipids profile were generally significantly higher in obese than non obese. The indicator waist/height ratio was the significant predictor for all types of dyslipidemia and all levels of serum lipids. Conclusions: the prevalence dyslipidemia and obesity are high and they are positively associated. Waist/height ratio was the most important predictor of dyslipidemia among adults.
背景:血脂异常和肥胖是许多非传染性慢性疾病的关键独立可改变危险因素。这些因素之间的关联模式可能有助于预防和控制。本研究旨在评估沙特阿拉伯王国成人的脂质特征与肥胖之间的关系,并确定血脂异常的人体测量预测因素。方法:采用世卫组织逐步方法收集和分析横断面研究数据,采用分层、多阶段、整群随机抽样技术选取4990名年龄在15- 64岁的沙特成年人。脂质谱(胆固醇类别和甘油三酯)用比色生化法测定。通过计算体重指数(BMI=Kg/m2)、腰臀围及比值、腰高比判定肥胖。结果:肥胖的总体患病率在33.8%到44.4%之间,血脂异常的总体患病率在25%到44%之间,这取决于血脂异常的类型和使用的人体测量学。肥胖者的血脂异常患病率和平均脂质浓度一般显著高于非肥胖者。腰高比指标是所有类型血脂异常和所有水平血脂的显著预测因子。结论:血脂异常与肥胖患病率较高,且两者呈正相关。腰高比是成人血脂异常最重要的预测指标。
{"title":"Anthropometric predictors of dyslipidemia among adults in Saudi Arabia","authors":"Abdalla A Saeed","doi":"10.2427/8733","DOIUrl":"https://doi.org/10.2427/8733","url":null,"abstract":"\u0000Background: dyslipidemia and obesity are key independent modifiable risk factors for many non communicable chronic diseases. Patterns of association between these factors may help prevention and control. This study aims to assess the association between lipids profile and obesity among adults in Kingdom of Saudi Arabia and identify anthropometric predictors of dyslipidemia. \u0000Methods: data were collected and analyzed from a cross-sectional study using WHO STEPwise approach that included 4 990 Saudi adults aged 15- 64 years selected by stratified, multistage, cluster random sampling technique. Lipid profiles (cholesterol categories and triglycerides) were determined spectrophotometrically by colorimetric biochemical methods. Obesity was determined by calculation of body mass index (BMI=Kg/m2), waist and hip circumferences and ratio and waist to height ratio. \u0000Results: the overall prevalence of obesity ranged from 33.8 to 44.4 % and the overall dyslipidemia prevalence ranged from about 25 to 44% depending on type of dyslipidemia and anthropometrics used. Prevalence of dyslipidemia and mean concentration of lipids profile were generally significantly higher in obese than non obese. The indicator waist/height ratio was the significant predictor for all types of dyslipidemia and all levels of serum lipids. \u0000Conclusions: the prevalence dyslipidemia and obesity are high and they are positively associated. Waist/height ratio was the most important predictor of dyslipidemia among adults. \u0000","PeriodicalId":45811,"journal":{"name":"Epidemiology Biostatistics and Public Health","volume":"72 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86350701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 18
Bevacizumab for advanced ovarian cancer treatment. A GRADE based approach 贝伐单抗用于晚期卵巢癌治疗。基于成绩的方法
Q3 Nursing Pub Date : 2022-07-08 DOI: 10.2427/8826
G. Pappagallo, V. Torri
Background: in advanced ovarian cancer, over the last 10 years no studies have demonstrated more appropriate therapeutic options compared to the current standard Carboplatin-Paclitaxel (Cb-P) regimen. Two phase III randomized studies (GOG-218 36 and ICON-7 37) have recently demonstrated the efficacy of bevacizumab (recombinant monoclonal antibody that binds with a high affinity to VEGF-A) in adjunct to Cb-P, with 12-15 months maintenance treatment. Methods: the quality of evidence provided was assessed by the use of the GRADE method. Each outcome (deemed to be essential for the purpose of evaluation of the intervention) was assessed to express the degree of confidence in the entity of the beneficial and/or harmful effects of the intervention. Thus, limitations in the quality of conducting the studies (risk of bias), direct applicability/relevance of results to the target population, and precision of results were taken into account. Results: the GOG-218 and the ICON7 study (high-risk subgroup) demonstrated with MODERATE confidence an improvement in critical outcomes PFS and OS, with an absolute reduction of 96 (GOG-218) – 103 (ICON-7) episodes of progression, and 40 (GOG-218) – 135 (ICON-7) deaths per 1 000 patients. A marked increase in risk of hypertension of Grade ≥3 was observed, with an absolute increase of 59 episodes per 1 000 patients in the ICON-7 study, and 157 episodes in the GOG-218 study, respectively, the majority of which were controlled by means of appropriate treatment. The increased risk of other adverse events considered was negligible. Conclusions: the positive effects produced should be viewed as taking prevalence over the negative effects (FAVOURABLE benefit/harm ratio).
背景:在晚期卵巢癌中,在过去的10年中,没有研究证明比目前标准的卡铂-紫杉醇(Cb-P)方案更合适的治疗选择。两项III期随机研究(GOG-218 36和ICON-7 37)最近证明了贝伐单抗(与VEGF-A高亲和力结合的重组单克隆抗体)辅助Cb-P治疗12-15个月的疗效。方法:采用GRADE法对证据质量进行评价。评估每个结果(被认为是评估干预措施的基本目的),以表达对干预措施的有益和/或有害影响的实体的信心程度。因此,研究质量的局限性(偏倚风险)、结果对目标人群的直接适用性/相关性以及结果的准确性都被考虑在内。结果:GOG-218和ICON7研究(高风险亚组)以中等可信度证明了关键结局PFS和OS的改善,绝对减少了96 (GOG-218) - 103 (ICON-7)次进展发作,每1000名患者40 (GOG-218) - 135 (ICON-7)例死亡。观察到≥3级高血压的风险显著增加,ICON-7研究中每1000名患者有59次发作的绝对增加,GOG-218研究中分别有157次发作的绝对增加,其中大部分通过适当的治疗得到控制。其他不良事件增加的风险可以忽略不计。结论:产生的积极影响应被视为比负面影响更普遍(有利的效益/危害比)。
{"title":"Bevacizumab for advanced ovarian cancer treatment. A GRADE based approach","authors":"G. Pappagallo, V. Torri","doi":"10.2427/8826","DOIUrl":"https://doi.org/10.2427/8826","url":null,"abstract":"\u0000Background: in advanced ovarian cancer, over the last 10 years no studies have demonstrated more appropriate therapeutic options compared to the current standard Carboplatin-Paclitaxel (Cb-P) regimen. Two phase III randomized studies (GOG-218 36 and ICON-7 37) have recently demonstrated the efficacy of bevacizumab (recombinant monoclonal antibody that binds with a high affinity to VEGF-A) in adjunct to Cb-P, with 12-15 months maintenance treatment. \u0000Methods: the quality of evidence provided was assessed by the use of the GRADE method. Each outcome (deemed to be essential for the purpose of evaluation of the intervention) was assessed to express the degree of confidence in the entity of the beneficial and/or harmful effects of the intervention. Thus, limitations in the quality of conducting the studies (risk of bias), direct applicability/relevance of results to the target population, and precision of results were taken into account. \u0000Results: the GOG-218 and the ICON7 study (high-risk subgroup) demonstrated with MODERATE confidence an improvement in critical outcomes PFS and OS, with an absolute reduction of 96 (GOG-218) – 103 (ICON-7) episodes of progression, and 40 (GOG-218) – 135 (ICON-7) deaths per 1 000 patients. A marked increase in risk of hypertension of Grade ≥3 was observed, with an absolute increase of 59 episodes per 1 000 patients in the ICON-7 study, and 157 episodes in the GOG-218 study, respectively, the majority of which were controlled by means of appropriate treatment. The increased risk of other adverse events considered was negligible. \u0000Conclusions: the positive effects produced should be viewed as taking prevalence over the negative effects (FAVOURABLE benefit/harm ratio). \u0000","PeriodicalId":45811,"journal":{"name":"Epidemiology Biostatistics and Public Health","volume":"107 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80928969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Epidemiology, Biostatistics and Public Health, EBPH: a new vision for two old journals 流行病学,生物统计学和公共卫生,EBPH:两个旧期刊的新愿景
Q3 Nursing Pub Date : 2022-07-08 DOI: 10.2427/8813
S. Boccia, C. Vecchia
The launch of this new journal, Epidemiology, Biostatistics and Public Health (EBPH), enables us to embrace new challenges, and renew our commitment to our readers, our authors and fellow editors, and ultimately to the public health community worldwide. EBPH is an open access journal streaming from two previous journals, one focused on public health (The Italian Journal of Public Health, http://ijphjournal.it/) [1-8], ...
《流行病学、生物统计与公共卫生》(EBPH)杂志的创刊使我们能够迎接新的挑战,并重申我们对读者、作者和编辑同仁的承诺,最终对全球公共卫生界的承诺。EBPH是一个开放获取的期刊,从以前的两个期刊流,一个专注于公共卫生(意大利公共卫生杂志,http://ijphjournal.it/)[1-8],…
{"title":"Epidemiology, Biostatistics and Public Health, EBPH: a new vision for two old journals","authors":"S. Boccia, C. Vecchia","doi":"10.2427/8813","DOIUrl":"https://doi.org/10.2427/8813","url":null,"abstract":"\u0000The launch of this new journal, Epidemiology, Biostatistics and Public Health (EBPH), enables us to embrace new challenges, and renew our commitment to our readers, our authors and fellow editors, and ultimately to the public health community worldwide. \u0000EBPH is an open access journal streaming from two previous journals, one focused on public health (The Italian Journal of Public Health, http://ijphjournal.it/) [1-8], ...","PeriodicalId":45811,"journal":{"name":"Epidemiology Biostatistics and Public Health","volume":"20 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87144929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
The use of fractal dimension methods in clinical epidemiology: an application for postural assessment 分形维数方法在临床流行病学中的应用:姿势评估的应用
Q3 Nursing Pub Date : 2022-07-08 DOI: 10.2427/8735
F. Masedu, Massimo Angelozzi, R. D. Giminiani, M. Valenti
Background: this study considers the analysis of postural sway by comparing the use of a fractal dimension outcome (DBOX) with the usual sway ellipse area (SEA), calculated by the least squares method. Both the response variables come from centre of pressure (COP) dynamics detected by means of a force platform. Methods: recent literature regarding postural stability assessment in subjects with muscularskeletal disorders, or neuromuscular diseases affecting their motor skills, has suggested, both for practical and theoretical reasons, the use of some fractal dimension as a good outcome measurement for overall postural status. A sample group of 24 male subjects was recruited. The postural stabilogram was recorded both with eyes open (EO) and eyes closed (EC) while standing upright. A matched-pair comparison of the sway ellipse area with the COP dynamics box counting dimension was performed. A ROC analysis of the outcome variables was performed. Then, a ROC comparison of the tests, using the area under the curve (AUC) index, was conducted. Results: the comparison of paired groups showed a statistically significant difference between EO and EC status, according to the sway ellipse area and the fractal dimension (p<0.05). The ROC analysis, describing the test performance in terms of AUC difference, was statistically significant (p<0.05). The comparison of the AUCs showed an overall superior performance of the DBOX with respect to SEA (p<0.05). Conclusions: this study showed a statistically significant better overall performance of DBOX with respect to SEA, suggesting possible improvements of clinical practice, as well as theoretical insights into the response patterns.
背景:本研究通过比较使用分形维数结果(DBOX)和使用最小二乘法计算的常用摇摆椭圆面积(SEA)来考虑姿势摇摆的分析。这两个响应变量均来自力平台检测到的压力中心动力学。方法:最近关于肌肉骨骼疾病或影响运动技能的神经肌肉疾病受试者的姿势稳定性评估的文献表明,出于实践和理论的原因,使用一些分形维数作为整体姿势状态的良好结果测量。招募了24名男性受试者作为样本。体位稳定图分别记录直立时睁眼(EO)和闭眼(EC)的状态。对摆动椭圆面积与COP动力学盒计数维数进行了配对比较。对结果变量进行ROC分析。然后,使用曲线下面积(AUC)指数对测试进行ROC比较。结果:两两组比较,从摆动椭圆面积和分形维数看,EO和EC状态差异有统计学意义(p<0.05)。ROC分析以AUC差异描述测试表现,差异有统计学意义(p<0.05)。auc的比较显示DBOX相对于SEA的整体性能优越(p<0.05)。结论:本研究显示DBOX相对于SEA的整体表现有统计学意义上的改善,提示可能的临床实践改进,以及对反应模式的理论见解。
{"title":"The use of fractal dimension methods in clinical epidemiology: an application for postural assessment","authors":"F. Masedu, Massimo Angelozzi, R. D. Giminiani, M. Valenti","doi":"10.2427/8735","DOIUrl":"https://doi.org/10.2427/8735","url":null,"abstract":"\u0000Background: this study considers the analysis of postural sway by comparing the use of a fractal dimension outcome (DBOX) with the usual sway ellipse area (SEA), calculated by the least squares method. Both the response variables come from centre of pressure (COP) dynamics detected by means of a force platform. \u0000Methods: recent literature regarding postural stability assessment in subjects with muscularskeletal disorders, or neuromuscular diseases affecting their motor skills, has suggested, both for practical and theoretical reasons, the use of some fractal dimension as a good outcome measurement for overall postural status. A sample group of 24 male subjects was recruited. The postural stabilogram was recorded both with eyes open (EO) and eyes closed (EC) while standing upright. A matched-pair comparison of the sway ellipse area with the COP dynamics box counting dimension was performed. A ROC analysis of the outcome variables was performed. Then, a ROC comparison of the tests, using the area under the curve (AUC) index, was conducted. \u0000Results: the comparison of paired groups showed a statistically significant difference between EO and EC status, according to the sway ellipse area and the fractal dimension (p<0.05). The ROC analysis, describing the test performance in terms of AUC difference, was statistically significant (p<0.05). The comparison of the AUCs showed an overall superior performance of the DBOX with respect to SEA (p<0.05). \u0000Conclusions: this study showed a statistically significant better overall performance of DBOX with respect to SEA, suggesting possible improvements of clinical practice, as well as theoretical insights into the response patterns. \u0000","PeriodicalId":45811,"journal":{"name":"Epidemiology Biostatistics and Public Health","volume":"21 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84470386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effectiveness of a perceptual - proprioceptive training with virtual visual feedback in healthy subjects: a pilot study 虚拟视觉反馈的知觉-本体感觉训练在健康受试者中的有效性:一项初步研究
Q3 Nursing Pub Date : 2022-07-07 DOI: 10.2427/8844
S. Vando, B. Unim, S. Cassarino, J. Padulo, D. Masala
Background: the aim of this pilot study was to evaluate whether proprioceptive-motor training using the Wii Balance Board (WBB) might improve postural sway in healthy subjects. Methods: twenty-five healthy subjects were trained for six weeks (two sessions per week) with 5 “video games”: Wii Fit Plus (WFP) program. Before and after training: Basic Balance, Single-leg Balance, Agility, Stability and Motion (lower limb: right-left and both leg) were measured using the Wii Balance Board. Results: the Wilcoxon Test showed improvements at the end of the training program compared to the baseline conditions. Basic Balance increased during the WFP (33.33%) and was associated with a 19.92% decrease in center of pressure (COP) lenght. The Single-leg Balance results incremented after the WFP (left 29.09% vs. right 47.92%) and accompanied by a decrement in COP (left 28.71% vs. right 30.45%). The values for the Agility test increased both in WFP and COP (28.57% and 58.57%, respectively). The Stability test scores increased in the WFP (66.67%) along with a consequent decrease in COP (10.53%). Finally, the Motion test values increased in the WFP (73.17%), whilst COP for this test decreased (12.02%). These results indicate that 6 weeks of virtual training produced a good adaptability. Younger participants (<20 years) demonstrated to be more responsive to dynamic stimulation with respect to those >20 years. Conclusions: significant improvements in all participants were observed, indicating that virtual training can influence posture and balance in healthy people. Because of its characteristics of low cost and easy availability, a portable system for balance training for everyone offers the possibility to more readily measure motor skill and to gauge improvement.
背景:本初步研究的目的是评估使用Wii平衡板(WBB)进行本体感觉运动训练是否可以改善健康受试者的姿势摇摆。方法:对25名健康受试者进行为期6周(每周2次)的5种“视频游戏”:Wii Fit Plus (WFP)程序。训练前后:使用Wii平衡板测量基本平衡,单腿平衡,敏捷性,稳定性和运动性(下肢:左右腿和双腿)。结果:与基线条件相比,Wilcoxon测试显示在训练计划结束时有所改善。在WFP期间,基本平衡增加(33.33%),与压力中心(COP)长度减少19.92%相关。单腿平衡结果在WFP之后增加(左侧29.09%对右侧47.92%),并伴随着COP的减少(左侧28.71%对右侧30.45%)。敏捷性测试值在WFP和COP中都增加了(分别为28.57%和58.57%)。WFP的稳定性测试分数增加了(66.67%),随之而来的是COP的下降(10.53%)。最后,运动测试值在WFP中增加(73.17%),而COP在该测试中下降(12.02%)。这些结果表明,6周的虚拟训练产生了良好的适应性。年轻参与者(20岁)。结论:所有参与者都观察到显著的改善,表明虚拟训练可以影响健康人的姿势和平衡。由于其低成本和易于获得的特点,为每个人的平衡训练便携式系统提供了更容易测量运动技能和衡量改进的可能性。
{"title":"Effectiveness of a perceptual - proprioceptive training with virtual visual feedback in healthy subjects: a pilot study","authors":"S. Vando, B. Unim, S. Cassarino, J. Padulo, D. Masala","doi":"10.2427/8844","DOIUrl":"https://doi.org/10.2427/8844","url":null,"abstract":"\u0000Background: the aim of this pilot study was to evaluate whether proprioceptive-motor training using the Wii Balance Board (WBB) might improve postural sway in healthy subjects. \u0000Methods: twenty-five healthy subjects were trained for six weeks (two sessions per week) with 5 “video games”: Wii Fit Plus (WFP) program. Before and after training: Basic Balance, Single-leg Balance, Agility, Stability and Motion (lower limb: right-left and both leg) were measured using the Wii Balance Board. \u0000Results: the Wilcoxon Test showed improvements at the end of the training program compared to the baseline conditions. Basic Balance increased during the WFP (33.33%) and was associated with a 19.92% decrease in center of pressure (COP) lenght. The Single-leg Balance results incremented after the WFP (left 29.09% vs. right 47.92%) and accompanied by a decrement in COP (left 28.71% vs. right 30.45%). The values for the Agility test increased both in WFP and COP (28.57% and 58.57%, respectively). The Stability test scores increased in the WFP (66.67%) along with a consequent decrease in COP (10.53%). Finally, the Motion test values increased in the WFP (73.17%), whilst COP for this test decreased (12.02%). These results indicate that 6 weeks of virtual training produced a good adaptability. Younger participants (<20 years) demonstrated to be more responsive to dynamic stimulation with respect to those >20 years. \u0000Conclusions: significant improvements in all participants were observed, indicating that virtual training can influence posture and balance in healthy people. Because of its characteristics of low cost and easy availability, a portable system for balance training for everyone offers the possibility to more readily measure motor skill and to gauge improvement. \u0000","PeriodicalId":45811,"journal":{"name":"Epidemiology Biostatistics and Public Health","volume":"37 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87298529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
he association of total and abdominal obesity with Health-Related Quality of Life in a sample of Greek healthy adults 在希腊健康成人样本中,总肥胖和腹部肥胖与健康相关生活质量的关系
Q3 Nursing Pub Date : 2022-07-07 DOI: 10.2427/8842
E. Theodoropoulou
Background: in the Greek population, the association between obesity and Health-Related Quality of Life (HRQoL) has not been examined so far. Thus, the purpose of the present study is to explore obesity-related predictors of HRQoL in a sample of Greek healthy adults. Methods: a cross-sectional design was used. The sample consisted of three hundred twenty seven healthy men (N=105) and women (N=222), between the ages of 30 and 50 years (mean age=39.57 ± 6.68) who lived in Athens. Body mass index (BMI), waist to hip ratio (WHR), and body fat (BF) were assessed. HRQoL was evaluated using the short-form 36 (SF-36) health survey, which consists of eight subscales and two health factors (physical and psychological health). Socio-demographic variables and health-related behaviours were assessed by questionnaires. Separate hierarchical regression analyses were conducted to examine the associations between BMI, WHR, BF and SF-36 health survey subscales and factors. Results: socio-demographic and health-related variables were moderately associated with the HRQoL subscales and factors. Furthermore, after controlling the socio-demographic variables and health-related behaviours, (a) BMI negatively predicted the physical functioning, physical role, bodily pain, and social functioning subscales, as well as the physical health factor and (b) WHR and BF negatively predicted the physical functioning subscale. However, the obesity indexes did not predict other psychological health subscales. Conclusions: the results indicated negative associations of BMI, WHR, BF with physical functioning and health in a sample of Greek healthy adults. Such data relating total and abdominal obesity to HRQoL, as assessed by BMI, WHR, and BF, have not been reported until now in the literature. One limitation of this study was that the sample size was relatively small and the results could not be generalized to the entire Greek population.
背景:在希腊人群中,肥胖与健康相关生活质量(HRQoL)之间的关系迄今尚未得到研究。因此,本研究的目的是在希腊健康成人样本中探讨肥胖相关的HRQoL预测因子。方法:采用横断面设计。样本包括327名生活在雅典的健康男性(N=105)和女性(N=222),年龄在30至50岁之间(平均年龄=39.57±6.68)。评估身体质量指数(BMI)、腰臀比(WHR)和体脂(BF)。HRQoL采用短表36 (SF-36)健康调查进行评估,该调查由8个分量表和2个健康因素(生理和心理健康)组成。社会人口变量和健康相关行为通过问卷进行评估。分别进行分层回归分析,检验BMI、WHR、BF和SF-36健康调查分量表和因素之间的关系。结果:社会人口统计学和健康相关变量与HRQoL亚量表和因子有中度相关性。此外,在控制社会人口学变量和健康相关行为后,BMI负向预测身体功能、身体角色、身体疼痛和社会功能分量表以及身体健康因素,WHR和BF负向预测身体功能分量表。然而,肥胖指数并不能预测其他心理健康量表。结论:结果表明,在希腊健康成人样本中,BMI、WHR、BF与身体功能和健康呈负相关。通过BMI、WHR和BF评估的总肥胖和腹部肥胖与HRQoL的相关数据,迄今为止尚未在文献中报道。本研究的一个局限性是样本量相对较小,结果不能推广到整个希腊人口。
{"title":"he association of total and abdominal obesity with Health-Related Quality of Life in a sample of Greek healthy adults","authors":"E. Theodoropoulou","doi":"10.2427/8842","DOIUrl":"https://doi.org/10.2427/8842","url":null,"abstract":"\u0000Background: in the Greek population, the association between obesity and Health-Related Quality of Life (HRQoL) has not been examined so far. Thus, the purpose of the present study is to explore obesity-related predictors of HRQoL in a sample of Greek healthy adults. \u0000Methods: a cross-sectional design was used. The sample consisted of three hundred twenty seven healthy men (N=105) and women (N=222), between the ages of 30 and 50 years (mean age=39.57 ± 6.68) who lived in Athens. Body mass index (BMI), waist to hip ratio (WHR), and body fat (BF) were assessed. HRQoL was evaluated using the short-form 36 (SF-36) health survey, which consists of eight subscales and two health factors (physical and psychological health). Socio-demographic variables and health-related behaviours were assessed by questionnaires. Separate hierarchical regression analyses were conducted to examine the associations between BMI, WHR, BF and SF-36 health survey subscales and factors. \u0000Results: socio-demographic and health-related variables were moderately associated with the HRQoL subscales and factors. Furthermore, after controlling the socio-demographic variables and health-related behaviours, (a) BMI negatively predicted the physical functioning, physical role, bodily pain, and social functioning subscales, as well as the physical health factor and (b) WHR and BF negatively predicted the physical functioning subscale. However, the obesity indexes did not predict other psychological health subscales. \u0000Conclusions: the results indicated negative associations of BMI, WHR, BF with physical functioning and health in a sample of Greek healthy adults. Such data relating total and abdominal obesity to HRQoL, as assessed by BMI, WHR, and BF, have not been reported until now in the literature. One limitation of this study was that the sample size was relatively small and the results could not be generalized to the entire Greek population. \u0000","PeriodicalId":45811,"journal":{"name":"Epidemiology Biostatistics and Public Health","volume":"18 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80050249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
期刊
Epidemiology Biostatistics and Public Health
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1