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Exploring the acceptability of Option B plus among HIV-positive Nigerian women engaged and not engaged in the prevention of mother-to-child transmission of HIV cascade: a qualitative study. 探讨艾滋病毒阳性尼日利亚妇女参与和不参与预防艾滋病毒母婴级联传播的可接受性:一项定性研究。
IF 1.1 4区 医学 Q4 HEALTH POLICY & SERVICES Pub Date : 2018-12-01 DOI: 10.1080/17290376.2018.1527245
Salome C Erekaha, Llewellyn J Cornelius, Melissa L Bessaha, Abdulmumin Ibrahim, Gabriel D Adeyemo, Mofoluwake Fadare, Manhattan Charurat, Echezona E Ezeanolue, Nadia A Sam-Agudu

The acceptability of lifelong antiretroviral therapy (ART) among HIV-positive women in high-burden Nigeria, is not well-known. We explored readiness of users and providers of prevention of mother-to-child transmission of HIV (PMTCT) services to accept lifelong ART -before Option B plus was implemented in Nigeria. We conducted 142 key informant interviews among 100 PMTCT users (25 pregnant-newly-diagnosed, 26 pregnant-in-care, 28 lost-to-follow-up (LTFU) and 21 postpartum women living with HIV) and 42 PMTCT providers in rural North-Central Nigeria. Qualitative data were manually analyzed via Grounded Theory. PMTCT users had mixed views about lifelong ART, strongly influenced by motivation to prevent infant HIV and by presence or absence of maternal illness. Newly-diagnosed women were most enthusiastic about lifelong ART, however postpartum and LTFU women expressed conditionalities for acceptance and adherence, including minimal ART side effects and potentially serious maternal illness. Providers corroborated user findings, identifying the postpartum period as problematic for lifelong ART acceptability/adherence. Option B plus scale-up in Nigeria will require proactively addressing PMTCT user fears about ART side effects, and continuous education on long-term maternal and infant benefits. Structural barriers such as the availability of trained providers, long clinic wait times and patient access to ART should also be addressed.

在负担沉重的尼日利亚,艾滋病毒阳性妇女对终身抗逆转录病毒治疗的接受程度尚不为人所知。在尼日利亚实施B +方案之前,我们探讨了预防母婴艾滋病毒传播服务的使用者和提供者是否愿意接受终身抗逆转录病毒治疗。我们对尼日利亚中北部农村地区的100名预防母婴传播使用者(25名新诊断的孕妇,26名接受护理的孕妇,28名失去随访(LTFU)和21名产后感染艾滋病毒的妇女)和42名预防母婴传播提供者进行了142次关键信息访谈。定性数据通过接地理论手工分析。预防母婴传播使用者对终身抗逆转录病毒治疗的看法不一,受到预防婴儿艾滋病毒的动机和母亲是否患病的强烈影响。新诊断的妇女对终身抗逆转录病毒治疗最感兴趣,然而产后和LTFU妇女对接受和坚持有条件,包括最小的抗逆转录病毒治疗副作用和潜在的严重产妇疾病。提供者证实了用户的发现,确定产后时期是终身ART可接受性/依从性的问题。方案B +在尼日利亚的推广将需要主动解决预防母婴传播使用者对抗逆转录病毒治疗副作用的担忧,并就母婴长期利益进行持续教育。还应解决结构性障碍,如缺乏训练有素的提供者、诊所等待时间长和患者获得抗逆转录病毒治疗。
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引用次数: 10
Violence, abuse and discrimination: key factors militating against control of HIV/AIDS among the LGBTI sector. 暴力、虐待和歧视:阻碍LGBTI群体控制艾滋病毒/艾滋病的关键因素。
IF 1.1 4区 医学 Q4 HEALTH POLICY & SERVICES Pub Date : 2018-12-01 DOI: 10.1080/17290376.2018.1492960
Dominic Targema Abaver, Elphina Nomabandla Cishe

The Lesbian, Gay, Bisexual, Transgender and Intersex (LGBTI) South Africans continue to face considerable challenges, including societal stigma, homophobic violence (particularly corrective rape), and high rates of sexually transmitted diseases and infections (particularly Human Immunodeficiency Virus (HIV)/AIDS) even when discrimination based on sexual orientation was outlawed by South African's post-apartheid constitution. This study was conducted to ascertain violence, abuse and discrimination against the LGBTI sector as key factors that hinder the smooth implementation of HIV/AIDS programme among sexually minority (LGBTI) group in Walter Sisulu University, South Africa. The self-structured questionnaire was used to collect data. The study involved 3048 purposively selected participants (1285 male and 1763 female) aged 17-38 years. About 70.5% of the participants witnessed physical attack as a form of violence against people in same-gender relationship; 47.7% disagreed that violent targeted at this sexually minority group is justified. The LGBTI face challenges which include verbal insults (937, 32.4%), bullying (532, 18.4%) and name-calling (1389, 48%). Discrimination against members of the LGBTI sector was witnessed in various forms: non-acceptance (981, 33.9%), disapproval of act of homosexuals (1308, 45.2) and denial of rights (327, 11.3). Violence, abuse and discrimination which constitute stigmatisation among the LGBTI sector are received with mix feeling. Some respondents justified the use of one or more of these key elements of stigmatisation against the LGBTI (6.6%, supports violence), others condemned these acts of stigmatisation (28.8%), against discrimination). Social stigma which resulted from violence, abuse and discrimination exist in this institution and is responsible for the unwillingness of disclosure of sexual orientation among the LGBTI members. An enabling environment should be created where the LGBTI members could come out freely to access programmes targeted at the prevention and control of HIV/AIDS.

南非女同性恋、男同性恋、双性恋、变性人和双性人(LGBTI)继续面临相当大的挑战,包括社会耻辱、同性恋暴力(特别是矫正性强奸)以及性传播疾病和感染率高(特别是人类免疫缺陷病毒(艾滋病毒)/艾滋病),尽管基于性取向的歧视已被南非后种族隔离宪法定为非法。本研究旨在确定对LGBTI群体的暴力,虐待和歧视是阻碍南非Walter Sisulu大学性少数群体(LGBTI)群体顺利实施艾滋病毒/艾滋病项目的关键因素。采用自结构化问卷收集数据。该研究涉及3048名有意选择的参与者(1285名男性和1763名女性),年龄在17-38岁之间。约70.5%的参与者目睹了对同性关系中的人的身体攻击,这是一种暴力形式;47.7%的人不认为针对性少数群体的暴力是合理的。LGBTI面临的挑战包括言语侮辱(937,32.4%),欺凌(532,18.4%)和辱骂(1389,48%)。对LGBTI群体成员的歧视以各种形式出现:不接受(981人,33.9%)、反对同性恋行为(1308人,45.2%)和剥夺权利(327人,11.3)。对于构成LGBTI群体耻辱的暴力、虐待和歧视,人们的感受是复杂的。一些受访者认为对LGBTI使用一种或多种污名化的关键因素是合理的(6.6%,支持暴力),另一些受访者谴责这些污名化行为(28.8%),反对歧视。由于暴力、虐待和歧视导致的社会污名在这个机构中存在,这也是LGBTI成员不愿公开性取向的原因。应该创造一个有利的环境,让LGBTI成员可以自由地参加针对预防和控制艾滋病毒/艾滋病的项目。
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引用次数: 19
The pull of soccer and the push of Xhosa boys in an HIV and drug abuse intervention in the Western Cape, South Africa. 在南非西开普省的一项艾滋病和药物滥用干预活动中,足球对科萨男孩的拉力和推力。
IF 1.1 4区 医学 Q4 HEALTH POLICY & SERVICES Pub Date : 2018-12-01 DOI: 10.1080/17290376.2018.1541024
Melissa Medich, Deborah Mindry, Mark Tomlinson, Mary Jane Rotheram-Borus, Jason Bantjes, Dallas Swendeman

There is growing interest in engaging men and boys in health and development programmes targeting the intersection of HIV risk, substance abuse, and violence. Understanding the conceptualisations of masculinities or masculine identities that shape both behaviours and opportunities for intervention is central to advancing the global agenda to engage men in health and development interventions. This paper examines an intervention using soccer and job training to engage and deliver activities for HIV prevention, substance abuse, and gender-based violence in a South African township. A literature review provides theoretical, historical and social context for the intersection of gender, masculinity, soccer, violence, and sexual relationships. Qualitative data from in-depth interviews and focus groups is analysed using theoretical and contextual frames to elucidate the negotiation of shifting, contradictory, and conflicting masculine roles. Results highlight how changing risky, normative behaviours among young men is a negotiated process entailing men's relationships with women and with other men.

让男性和男童参与针对艾滋病风险、药物滥用和暴力交叉问题的健康与发展计划的兴趣与日俱增。了解塑造男性行为和干预机会的男性概念或男性身份,对于推动全球议程,让男性参与健康与发展干预至关重要。本文研究了一项干预措施,该措施利用足球和工作培训,在南非的一个乡镇开展艾滋病预防、药物滥用和性别暴力活动。文献综述为性别、男性气质、足球、暴力和性关系的交叉提供了理论、历史和社会背景。利用理论和背景框架,对深入访谈和焦点小组的定性数据进行了分析,以阐明男性角色的转变、矛盾和冲突。研究结果凸显了年轻男性改变危险、规范行为的过程是一个涉及男性与女性和其他男性关系的协商过程。
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引用次数: 0
Health care users' knowledge, attitudes and perceptions of HIV self-testing at selected gateway clinics at eThekwini district, KwaZulu-Natal province, South Africa. 在南非夸祖鲁-纳塔尔省eThekwini区选定的门户诊所,医护人员对艾滋病毒自我检测的知识、态度和看法。
IF 1.1 4区 医学 Q4 HEALTH POLICY & SERVICES Pub Date : 2018-12-01 DOI: 10.1080/17290376.2018.1517607
Sibongiseni Daphney Gumede, Maureen Nokuthula Sibiya

Progress in promoting knowledge of HIV status has been made globally, but half of all people living with HIV are still unaware of their HIV status. It is argued the new innovative HIV self-testing strategy could increase the uptake of HIV testing among the people. The aim of the study was to assess outpatients' health care user's knowledge, attitudes and perceptions towards HIV self-testing (HIVST) at selected Gateway clinics at eThekwini District, KwaZulu-Natal Province, South Africa. The objectives of the study were to determine health care users' knowledge of HIVST, assess health care users' attitudes and perceptions towards HIVST and establish if there is any relationship between knowledge, attitudes and perceptions of health care users towards HIVST. A quantitative, non-experimental descriptive design was used to determine knowledge, attitudes and perceptions of health care users at three purposefully selected Addington, R. K. Khan and Prince Mshiyeni Memorial Hospital Gateway clinics at eThekwini Health District. A convenience sampling of 442 respondents were sampled from the three study sites. Results of the study revealed that health care users had a reasonable knowledge of HIV self-testing and there were indications that they could use it if it can be made freely available to the public and be properly regulated. Generally, health care users indicated positive attitudes towards HIV self-testing. Nevertheless, issues of lack of pre and post-test counselling, false negative results and sale of unregulated testing kits seemed to be issues of concern that require addressing if HIV self-testing is to be promulgated in South Africa.

全球在提高对艾滋病毒状况的认识方面取得了进展,但仍有一半的艾滋病毒感染者不知道自己的艾滋病毒状况。有人认为,新的创新艾滋病毒自我检测策略可以提高人们对艾滋病毒检测的接受率。该研究的目的是评估南非夸祖鲁-纳塔尔省eThekwini区选定Gateway诊所门诊医疗保健用户对艾滋病毒自我检测(HIVST)的知识、态度和看法。该研究的目的是确定医疗保健用户对HIVST的知识,评估医疗保健用户对待HIVST的态度和看法,并确定医疗保健使用者对待HIVST知识、态度和看法之间是否存在任何关系。采用定量、非实验性描述性设计,确定了三家有目的选择的阿丁顿、R.K.Khan和特赫维尼卫生区Mshiyeni王子纪念医院Gateway诊所的医护人员的知识、态度和看法。从三个研究地点对442名受访者进行了方便抽样。研究结果显示,医疗保健使用者对艾滋病毒自我检测有合理的了解,有迹象表明,如果可以向公众免费提供并得到适当的监管,他们可以使用它。一般来说,卫生保健使用者对艾滋病毒自我检测表现出积极态度。尽管如此,如果要在南非颁布艾滋病毒自我检测,缺乏检测前和检测后咨询、假阴性结果和销售不受监管的检测试剂盒等问题似乎是需要解决的问题。
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引用次数: 0
Longitudinal analysis of HIV risk behaviour patterns and their predictors among public primary care patients with tuberculosis in South Africa. 南非公共初级保健结核病患者艾滋病毒风险行为模式及其预测因素的纵向分析。
IF 1.1 4区 医学 Q4 HEALTH POLICY & SERVICES Pub Date : 2018-12-01 DOI: 10.1080/17290376.2018.1433057
Karl Peltzer

The goal of this study was to identify various HIV risk behaviours among tuberculosis (TB) patients in a longitudinal study design in South Africa. In 42 public primary healthcare facilities in three districts in three provinces, adult new TB and TB retreatment patients with hazardous or harmful alcohol use were interviewed within 1 month of initiation of anti-TB treatment and were followed up at 6 months. The total sample with a complete 6-month follow-up assessment was 853. At the follow-up assessment, several HIV risk behaviours significantly reduced from baseline to follow-up. In multivariate Generalized Estimating Equations logistic regression analyses, high poverty (odds ratio (OR): 2.68, 95% confidence interval (CI): 1.56-4.62), Posttraumatic Stress Disorder (PTSD) symptoms (OR = 1.55, 95% CI = 1.03-2.36), and sexual partner on antiretroviral therapy (ART) (OR = 1.84, 95% CI = 1.09-3.10) were associated with a higher odds, and excellent/very good perceived health status (OR: 0.61, 95% CI: 0.37-0.98), severe psychological stress (OR = 0.51, 95% CI = 0.34-0.77), and HIV non-disclosure to most recent sexual partner (OR = 0.40, 95% CI = 0.25-0.65) were associated with a lower odds of inconsistent condom use. Being HIV positive (OR = 4.18, 95% CI = 2.68-6.53) and excellent/very subjective health status (OR = 2.98, 95% CI = 1.73-5.13) were associated with a higher odds, and having PTSD symptoms (OR = 0.60, 95% CI = 0.36-0.99), being on ART (OR = 0.48, 95% CI = 0.25-0.95), having a sexual partner on ART (OR = 0.41, 95% CI = 0.18-0.96), and HIV status non-disclosure (OR = 0.25, 95% CI = 0.15-0.41) were associated with a lower odds of having sex with an HIV-positive or HIV status unknown person. High poverty index (OR = 1.97, 95% CI = 1.19-3.25) and having a sexual partner on ART (OR = 4.37, 95% CI = 1.82-10.48) were associated with a higher odds, and having a partner with HIV-negative status (OR = 0.29, 95% CI = 0.16-0.51) and inconsistent condom use (OR = 0.39, 95% CI = 0.24-0.64) were associated with a lower odds of HIV status non-disclosure at last sex. The study found that among TB patients with problem drinking over a 6-month TB treatment period, the frequency of some HIV risk behaviours (inconsistent condom use) declined (OR = 0.64, 95% CI = 0.41-0.98), but also persisted at a high-level calling for a strengthening and integration of HIV prevention into TB management.

本研究的目的是在南非的一项纵向研究设计中确定结核病(TB)患者的各种艾滋病毒风险行为。在3省3个区的42个公共初级卫生保健机构中,在开始抗结核治疗1个月内对成年新发结核病患者和危险或有害饮酒的结核病再治疗患者进行了访谈,并在6个月时进行了随访。完成6个月随访评估的总样本为853例。在随访评估中,从基线到随访期间,若干艾滋病毒风险行为显著减少。在多元广义估计方程logistic回归分析中,高度贫困(优势比(OR): 2.68, 95%可信区间(CI): 1.56-4.62)、创伤后应激障碍(PTSD)症状(OR = 1.55, 95% CI = 1.03-2.36)和性伴侣接受抗逆转录病毒治疗(ART) (OR = 1.84, 95% CI = 1.09-3.10)与较高的几率相关,以及良好/非常好的感知健康状况(OR: 0.61, 95% CI:0.37-0.98)、严重的心理压力(OR = 0.51, 95% CI = 0.34-0.77)和未向最近的性伴侣透露艾滋病毒(OR = 0.40, 95% CI = 0.25-0.65)与不一致使用避孕套的几率较低相关。HIV阳性(或= 4.18,95% CI = 2.68 - -6.53)和优秀的/非常主观的健康状态(或= 2.98,95% CI = 1.73 - -5.13)被关联到一个更高的可能性,和创伤后应激障碍症状(或= 0.60,95% CI = 0.36 - -0.99),在艺术(或= 0.48,95% CI -0.95 = 0.25),对艺术产生了性伴侣(或= 0.41,95% CI = 0.18 - -0.96),和艾滋病毒状况保密(或= 0.25,95% CI = 0.15 - -0.41)有关做爱的几率较低的艾滋病毒阳性或艾滋病毒状况未知的人。高贫困指数(OR = 1.97, 95% CI = 1.19-3.25)和性伴侣接受抗逆转录病毒治疗(OR = 4.37, 95% CI = 1.82-10.48)与较高的几率相关,而性伴侣呈HIV阴性(OR = 0.29, 95% CI = 0.16-0.51)和不一致使用安全套(OR = 0.39, 95% CI = 0.24-0.64)与最后性行为中HIV状态不披露的几率较低相关。该研究发现,在6个月的结核病治疗期间有饮酒问题的结核病患者中,一些艾滋病毒风险行为(不一致使用安全套)的频率下降了(OR = 0.64, 95% CI = 0.41-0.98),但也坚持要求加强艾滋病毒预防并将其纳入结核病管理。
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引用次数: 4
HIV/AIDS and older adults in Cameroon: Emerging issues and implications for caregiving and policy-making. 喀麦隆的艾滋病毒/艾滋病与老年人:新出现的问题及其对护理和决策的影响。
IF 1.1 4区 医学 Q4 HEALTH POLICY & SERVICES Pub Date : 2018-12-01 DOI: 10.1080/17290376.2018.1433059
Perpetua Lum Tanyi, André Pelser, Joseph Okeibunor

The burden of human immunodeficiency virus (HIV) infection and acquired immune deficiency syndrome (AIDS) on the elderly population in three divisions within the Northwest Region of Cameroon was examined. Data for this paper were extracted from a larger study which had been conducted concerning the burden of HIV infection and AIDS on the older adults in the Northwest Region of Cameroon. Using in-depth interviews (IDIs) and focus group discussions (FGDs), data were collected from 36 participants who were purposively selected from the three divisions which had been chosen randomly. 6 FGD sessions were held with 30 women aged 60 years and above and who were affected by HIV infection and AIDS, while IDIs sessions were held with 6 male community leaders. The results revealed that HIV infection and AIDS has added another dimension to the role of older persons. HIV infection and AIDS affects older people in diverse ways, as they have to look after themselves, their sick children and are often also left to look after their grandchildren orphaned by HIV infection and AIDS. These emerging issues in their lives make them vulnerable to health, social, economic and psychological challenges, and place a burden on them as caregivers instead of being cared for in their old age. Apart from increased direct expenditures, taking care of victims of HIV infection and AIDS requires older people to stay away from social, religious and community activities. The results showed that the loss of a child to HIV infection and AIDS affects the economic/financial well-being, participation in social/religious interactions as well as the community activities of older people participants. The implications of these findings for caregiving and social policy are discussed.

对喀麦隆西北地区三个省老年人口的人体免疫缺陷病毒(艾滋病毒)感染和获得性免疫缺陷综合症(艾滋病)负担进行了调查。本文的数据摘自一项关于喀麦隆西北地区老年人艾滋病毒感染和艾滋病负担的大型研究。采用深度访谈(IDIs)和焦点小组讨论(fgd),从随机选择的三个部门中有意选择的36名参与者收集数据。与30名60岁及以上感染艾滋病毒和艾滋病的妇女举行了6次妇女健康评估会议,与6名男性社区领导人举行了妇女健康评估会议。结果显示,艾滋病毒感染和艾滋病为老年人的作用增加了另一个层面。艾滋病毒感染和艾滋病以各种方式影响老年人,因为他们必须照顾自己和生病的子女,而且往往还要照顾因感染艾滋病毒和艾滋病而成为孤儿的孙辈。他们生活中出现的这些新问题使他们容易受到健康、社会、经济和心理挑战的影响,并使他们成为照顾者的负担,而不是在老年时得到照顾。除了增加直接支出外,照顾艾滋病毒感染和艾滋病受害者要求老年人远离社会、宗教和社区活动。结果表明,儿童死于艾滋病毒感染和艾滋病会影响老年人的经济/财务状况、社会/宗教互动的参与以及社区活动。讨论了这些发现对护理和社会政策的影响。
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引用次数: 11
Achievement of interventions on HIV infection prevention among migrants in China: A meta-analysis. 中国流动人口预防艾滋病感染干预措施的成果:荟萃分析。
IF 0.9 4区 医学 Q4 HEALTH POLICY & SERVICES Pub Date : 2018-12-01 DOI: 10.1080/17290376.2018.1451773
Rui Zhang, Ling Chen, Ya Deng Cui, Ge Li

In China, migrants with acquired immunodeficiency syndrome (AIDS) have become a serious problem in the field of AIDS prevention. This study aimed to evaluate the efficacy of interventions for human immunodeficiency virus (HIV) infection prevention for migrants in China and to identify factors associated with intervention efficacy. A computerized literature search of the Chinese National Knowledge Infrastructure, Wan Fang, and PubMed databases was conducted to collect related articles published in China. Only self-control intervention studies or studies containing sections regarding self-control interventions wherein the method of intervention was health education were included. Rev Manager 5.3 software was used to analyze the intervention effects in terms of knowledge, attitude, and behavior indexes. Relative to pre-intervention, the HIV interventions showed statistically significant efficacy in terms of sexual transmission of HIV, condom use for HIV prevention, change in attitude towards HIV/AIDS patients, incidence of commercial sex behavior, and recent condoms use during sex (P < .01). Moreover, the baseline rate of migrants, intervention time, peer education, region, and education background were factors influencing the efficacy of the intervention. Significant improvement in terms of knowledge of sexual transmission of HIV and attitudes and behaviors among migrants was observed; however, based on the findings of previous studies, the interventions should be customized for different people from different districts in China. Further research is needed to evaluate subgroups of migrants in China according to their baseline characteristics.

在中国,获得性免疫缺陷综合征(艾滋病)移民已成为艾滋病预防领域的一个严重问题。本研究旨在评估中国流动人口预防人类免疫缺陷病毒(HIV)感染干预措施的效果,并确定与干预效果相关的因素。研究人员利用计算机在中国知网、万方数据库和PubMed数据库中进行文献检索,收集在中国发表的相关文章。仅纳入自我控制干预研究或包含自我控制干预部分的研究,其中干预方法为健康教育。使用Rev Manager 5.3软件从知识、态度和行为指标分析干预效果。与干预前相比,艾滋病干预措施在艾滋病性传播、使用安全套预防艾滋病、改变对艾滋病患者的态度、商业性行为发生率以及最近在性行为中使用安全套等方面的效果均有统计学意义(P<0.05)。
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引用次数: 0
Effects of adolescent exposure to behaviour change interventions on their HIV risk reduction in Northern Malawi: a situation analysis. 马拉维北部青少年接触行为改变干预措施对其艾滋病毒风险降低的影响:一项情况分析。
IF 1.1 4区 医学 Q4 HEALTH POLICY & SERVICES Pub Date : 2018-12-01 DOI: 10.1080/17290376.2018.1529612
M Mwale, A S Muula

Understanding adolescents' translation of HIV and AIDS-related behaviour change interventions (BCI) knowledge and skills into expected behavioural outcomes helps us appreciate behaviour change dynamics among young people and informs evidence-based programming. We explored the effects of adolescents' exposure to BCI on their HIV risk reduction in selected schools in Nkhatabay and Mzimba districts and Mzuzu city in Northern Malawi. The study used questionnaires as instruments. Data were collected between January and April 2017. Adolescent boys and girls [n = 552], ages 11-19 were randomly sampled to participate. Data analysis was through multiple regression and content analysis. Respondents included 324 female [58.7%] and 228 male [41.3%]. Multiple regression analysis indicated that exposure to BCI did not affect risk reduction in the study area. The best stepwise model isolated sexual experience ([Beta = .727, p = .0001, p < .05]) as having the strongest correlation with the dependent variable - risk reduction. BCI exposure was stepwise excluded ([Beta = -.082, p = .053, p > .05]). There was therefore no evidence against the null hypothesis of no relationship between adolescent exposure to BCI and their HIV risk reduction. Overall there was limited BCI knowledge and skills translation to behavioural risk reduction. The study points to the need to evaluate and redesign adolescent BCI in line with current behavioural dynamics among young people in Malawi. The findings have been used to inform the design and programming of a model to be tested for feasibility through a quasi-experiment in the second phase of our project.

了解青少年将艾滋病毒和艾滋病相关的行为改变干预(BCI)知识和技能转化为预期的行为结果,有助于我们了解年轻人的行为改变动态,并为循证规划提供信息。我们在马拉维北部的Nkhatabay和Mzimba地区以及Mzuzu市的选定学校探讨了青少年接触脑机接口对降低其艾滋病毒风险的影响。这项研究使用问卷作为工具。数据收集于2017年1月至4月。随机抽取11-19岁的青春期男女[n = 552]参与研究。数据分析采用多元回归和内容分析。其中女性324人(58.7%),男性228人(41.3%)。多元回归分析表明,暴露于脑机损伤不影响研究区域的风险降低。最佳逐步模型分离性经验([Beta =。727, p =。0001, p .05])。因此,没有证据反对“青少年接触脑机脑损伤与其艾滋病毒风险降低之间没有关系”的零假设。总体而言,脑机接口知识和技能转化为减少行为风险的能力有限。该研究指出,需要根据马拉维年轻人目前的行为动态来评估和重新设计青少年脑机接口。研究结果已被用于通知模型的设计和编程,该模型将通过我们项目第二阶段的准实验进行可行性测试。
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引用次数: 11
Health-related quality of life and associated factors in adults living with HIV in Rwanda. 卢旺达成人艾滋病毒感染者的健康相关生活质量及相关因素。
IF 1.1 4区 医学 Q4 HEALTH POLICY & SERVICES Pub Date : 2018-12-01 DOI: 10.1080/17290376.2018.1520144
Juvenal Biraguma, Eugene Mutimura, José M Frantz

In Rwanda, as in other sub-Saharan African (SSA) countries, life expectancy of people living with HIV (PLWH) has increased dramatically as a result of combined antiretroviral therapy (cART). People living with HIV can now live longer but with increasing rates of non-communicable diseases (NCDs). Thus, prevention of NCD comorbidities in PWLHI is crucial to maintain and gain health-related benefits and to maximise the health-related quality of life (HRQOL) in the long-term management of PLWH. This study determines the association between physical and mental health-related dimensions of quality of life (QOL) with behavioural and biological risk factors, after controlling socio-demographic and HIV-related factors in adults living with HIV in Rwanda. A cross-sectional study using the WHO STEPwise approach and Kinyarwanda version of the MOS-HIV Health Survey, risk factors for NCDs and HRQOL were analysed for 794 PLWH, both HIV+ on ART and ART-naïve. Multiple regression analysis was used to examine the relationship between CMD risk factors and physical health and mental health summary scores. A total of 794 participants were interviewed. The mean age of the sample was 37.9 (±10.8) years and the majority of the participants were women (n = 513; 64.6%). About 16.2% reported daily smoking, 31.4% reported harmful alcohol use and 95% reported insufficient consumption of vegetables and fruits while 26.1% reported being physically inactive. 18.4% were overweight 43.4% had abdominal obesity, i.e. waist-hip-ratio (WHR) ≥0.95 in males and 0.85 in females. High blood pressure (HBP), i.e. systolic blood pressure (SBP) of ≥140 mmHg, or diastolic blood pressure (DBP) ≥90 mmHg was 24.4%. The results reveal that mean physical health summary and mental health summary score values were 63.96 ± 11.68 and 53.43 ± 10.89, respectively. While participants indicated that tobacco users and those who had abdominal obesity reported poor mental HRQOL, physical inactivity and hypertension have a negative impact on physical HRQOL. In addition, certain socio-demographic and HIV-related variables - specifically being unmarried, lack of HIV disclosure and low CD4 count (less 350 cell counts /mm3) - were associated with significantly lower mental and physical dimensions of quality of life. The results of this study reveal that behavioural and biological risk factors for NCDs were significantly associated with a lower HRQOL. These research findings also suggest that the assessment of the association between behavioural and biological risk factors for NCDs and a HRQOL provides opportunities for targeted counselling and secondary prevention efforts, so that health care providers can implement strategies that have a significant impact on the HRQOL.

在卢旺达,与其他撒哈拉以南非洲国家一样,由于抗逆转录病毒联合治疗,艾滋病毒感染者的预期寿命大幅增加。艾滋病毒感染者现在可以活得更长,但非传染性疾病的发病率也在上升。因此,在PLWH的长期管理中,预防非传染性疾病合并症对于维持和获得与健康相关的益处以及最大限度地提高与健康相关的生活质量(HRQOL)至关重要。本研究在控制卢旺达艾滋病毒感染者的社会人口统计学和艾滋病毒相关因素后,确定了生活质量(QOL)的身心健康相关维度与行为和生物学风险因素之间的关联。采用世卫组织逐步方法和卢旺达版的艾滋病毒健康调查的横断面研究,分析了794名艾滋病毒+抗逆转录病毒治疗和ART-naïve艾滋病毒感染者的非传染性疾病风险因素和HRQOL。采用多元回归分析检验CMD危险因素与身体健康和心理健康总结得分的关系。共有794名参与者接受了采访。样本的平均年龄为37.9(±10.8)岁,大多数参与者为女性(n = 513;64.6%)。约16.2%报告每天吸烟,31.4%报告有害饮酒,95%报告蔬菜和水果摄入不足,26.1%报告缺乏运动。18.4%超重,43.4%腹部肥胖,即腰臀比(WHR)男性≥0.95,女性≥0.85。高血压(HBP),即收缩压(SBP)≥140 mmHg或舒张压(DBP)≥90 mmHg占24.4%。结果显示,身体健康总结和心理健康总结平均分分别为63.96±11.68和53.43±10.89。虽然参与者表示,吸烟者和腹部肥胖的人报告的精神HRQOL较差,但缺乏运动和高血压对身体HRQOL有负面影响。此外,某些社会人口统计学和艾滋病毒相关变量-特别是未婚,缺乏艾滋病毒披露和低CD4计数(少于350细胞计数/mm3) -与生活质量的精神和身体维度显着降低相关。本研究结果显示,非传染性疾病的行为和生物学风险因素与较低的HRQOL显著相关。这些研究结果还表明,评估非传染性疾病的行为和生物学风险因素与HRQOL之间的关联,为有针对性的咨询和二级预防工作提供了机会,从而使卫生保健提供者能够实施对HRQOL有重大影响的战略。
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引用次数: 24
Determinants of disclosure and non-disclosure of HIV-positive status, by pregnant women in rural South Africa. 南非农村孕妇披露和不披露艾滋病毒阳性状况的决定因素。
IF 1.1 4区 医学 Q4 HEALTH POLICY & SERVICES Pub Date : 2018-12-01 DOI: 10.1080/17290376.2018.1529613
Shandir Ramlagan, Gladys Matseke, Violeta J Rodriguez, Deborah L Jones, Karl Peltzer, Robert A C Ruiter, Sibusiso Sifunda

Disclosure of HIV status remains one of the major challenges to the effectiveness of the prevention of mother to child transmission of HIV in rural areas in South Africa. This study aimed at assessing the determinants of HIV status disclosure among HIV infected pregnant women who have disclosed their HIV status to someone, as well as among those who have disclosed to their partners. Cross-sectional data was collected from 673 HIV sero-positive pregnant women receiving antenatal care services at 12 Community Health Centers in Mpumalanga province. Results indicated that over two-thirds (72.1%) disclosed their status to someone, while just over half (58.4%) disclosed to their partners. Multivariate analysis showed that both disclosure of ones HIV status to someone and to their male partners was significantly associated with increase in antiretroviral therapy (ART) adherence, the known HIV positive status of their partner, and male involvement during pregnancy. Participants who were diagnosed HIV positive during this current pregnancy were less likely to disclose their HIV status to someone. Non-disclosure during current pregnancy highlights a need for interventions that will encourage disclosure among HIV positive women, with a particular focus on those who are newly diagnosed. The findings also need to integrate male partner involvement and partner disclosure during pregnancy.

在南非农村地区,公开艾滋病毒感染状况仍然是有效预防艾滋病毒母婴传播的主要挑战之一。本研究旨在评估已向他人公开艾滋病毒感染状况的孕妇以及已向伴侣公开艾滋病毒感染状况的孕妇公开艾滋病毒感染状况的决定因素。我们从姆普马兰加省 12 个社区医疗中心接受产前保健服务的 673 名艾滋病毒血清反应呈阳性的孕妇中收集了横断面数据。结果显示,超过三分之二(72.1%)的孕妇向他人透露了自己的感染状况,而略高于一半(58.4%)的孕妇向伴侣透露了自己的感染状况。多变量分析表明,向他人和男性伴侣公开自己的艾滋病病毒感染状况与坚持抗逆转录病毒疗法(ART)、伴侣的已知艾滋病病毒呈阳性状况以及男性参与妊娠有很大关系。在本次怀孕期间被诊断为 HIV 阳性的参与者不太可能向他人透露自己的 HIV 感染状况。在当前怀孕期间不披露情况的情况突出表明,有必要采取干预措施,鼓励艾滋病毒呈阳性的妇女披露情况,尤其是那些新诊断出艾滋病毒呈阳性的妇女。研究结果还需要将男性伴侣的参与和伴侣在怀孕期间披露情况结合起来。
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引用次数: 0
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Sahara J-Journal of Social Aspects of Hiv-Aids
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