The Healthy School (or Health-Promoting School as a term used by WHO and other countries) is a whole-school approach to promoting health in a school setting. Healthy Schools and Health-Promoting Schools frameworks extend around the globe are important strategies that provide opportunities to improve the health of children and adolescents and to tackle health inequalities in the population. Two decades since the Healthy Schools framework was advocated in Saudi Arabia. This paper sets out to revie
{"title":"Healthy Schools Framework in Saudi Arabia: A Narrative Review","authors":"Saeed Ghurmallah AlZahrani","doi":"10.51847/lj2fbaa0vm","DOIUrl":"https://doi.org/10.51847/lj2fbaa0vm","url":null,"abstract":"The Healthy School (or Health-Promoting School as a term used by WHO and other countries) is a whole-school approach to promoting health in a school setting. Healthy Schools and Health-Promoting Schools frameworks extend around the globe are important strategies that provide opportunities to improve the health of children and adolescents and to tackle health inequalities in the population. Two decades since the Healthy Schools framework was advocated in Saudi Arabia. This paper sets out to revie","PeriodicalId":46106,"journal":{"name":"International Journal of Pharmaceutical Research and Allied Sciences","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135077883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Use of Medicinal Herbs to Treat Male Infertility in Jordan: Evidence-Based Review","authors":"Deniz M. Al-tawalbeh, Roba Bdeir, Joud Al-Momani","doi":"10.51847/42rwhfit62","DOIUrl":"https://doi.org/10.51847/42rwhfit62","url":null,"abstract":"","PeriodicalId":46106,"journal":{"name":"International Journal of Pharmaceutical Research and Allied Sciences","volume":"1 1","pages":""},"PeriodicalIF":0.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70811879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
P. Devi, Yashi Asthana, A. Sumitha, Ivo Romauld Sagayaraj
The main aim of this study is to determine the bioactive compounds which have drug-like properties and has the potential to combat the spike-glycoprotein of SARS-CoV-2. The 6LXT protein of covid-19 was chosen from the protein data bank as a target protein. The compounds which are potentially capable to bind with the target were picked from the PubChem database and docked using the tool Autodock 4.2. Molecular docking of the molecules was done with the best conformations of the ligands and grid size was selected according to the hit compounds' interaction with the target protein. The ligand binding sites with the target molecules were predicted using MetaPocket 2.0. The docking Score of 50 compounds wascarried out and also toxicity studies were carried out. The compounds selected were calculated to identify the best conformations having drug-likeness properties. The top 10 compounds were chosen for the structure-activity relationship based on their binding interactions with the protein and ligand. The ligands then underwent the pharmacokinetic analysis followed by Lipinski's and all the results were finalized and categorized. ManzamineA, Imatinib, and basotinib were elected as the peak compounds with the binding energy -9.01kcal/mol, -8.71kcal/mol, and -8.01kcal/mol.
{"title":"Molecular Docking and the Pharmacokinetic Properties of the Anti-Viral Compounds Towards SARS-CoV- An In-silico Approach","authors":"P. Devi, Yashi Asthana, A. Sumitha, Ivo Romauld Sagayaraj","doi":"10.51847/z2mkwovoqc","DOIUrl":"https://doi.org/10.51847/z2mkwovoqc","url":null,"abstract":"The main aim of this study is to determine the bioactive compounds which have drug-like properties and has the potential to combat the spike-glycoprotein of SARS-CoV-2. The 6LXT protein of covid-19 was chosen from the protein data bank as a target protein. The compounds which are potentially capable to bind with the target were picked from the PubChem database and docked using the tool Autodock 4.2. Molecular docking of the molecules was done with the best conformations of the ligands and grid size was selected according to the hit compounds' interaction with the target protein. The ligand binding sites with the target molecules were predicted using MetaPocket 2.0. The docking Score of 50 compounds wascarried out and also toxicity studies were carried out. The compounds selected were calculated to identify the best conformations having drug-likeness properties. The top 10 compounds were chosen for the structure-activity relationship based on their binding interactions with the protein and ligand. The ligands then underwent the pharmacokinetic analysis followed by Lipinski's and all the results were finalized and categorized. ManzamineA, Imatinib, and basotinib were elected as the peak compounds with the binding energy -9.01kcal/mol, -8.71kcal/mol, and -8.01kcal/mol.","PeriodicalId":46106,"journal":{"name":"International Journal of Pharmaceutical Research and Allied Sciences","volume":"1 1","pages":""},"PeriodicalIF":0.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70842002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ahmed Hamad Almohammed, Afrah Mohaimeed Altaymani, Ziyad Muharib N Alruwaili, Renad Mohammed Abdulrahman Alnasser
{"title":"Influence of Image Editing Practices and Social Media on Seeking Cosmetic Skin Care, Al-Jouf, Saudi Arabia","authors":"Ahmed Hamad Almohammed, Afrah Mohaimeed Altaymani, Ziyad Muharib N Alruwaili, Renad Mohammed Abdulrahman Alnasser","doi":"10.51847/m6n0vl1vfu","DOIUrl":"https://doi.org/10.51847/m6n0vl1vfu","url":null,"abstract":"","PeriodicalId":46106,"journal":{"name":"International Journal of Pharmaceutical Research and Allied Sciences","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135585128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hanan M Alharbi, T. Alqahtani, Afnan S. Batubara, Aisha Alshaer, Bushra Alqurashi, Lama Bahwairth, Huda Khawaji, And Majd Almohammadi
{"title":"Enhancing the Dissolution of Oral Dasatinib Tablets Using Zein–Hydroxypropyl Methylcellulose Solid Dispersions","authors":"Hanan M Alharbi, T. Alqahtani, Afnan S. Batubara, Aisha Alshaer, Bushra Alqurashi, Lama Bahwairth, Huda Khawaji, And Majd Almohammadi","doi":"10.51847/crbi2n6klg","DOIUrl":"https://doi.org/10.51847/crbi2n6klg","url":null,"abstract":"","PeriodicalId":46106,"journal":{"name":"International Journal of Pharmaceutical Research and Allied Sciences","volume":"1 1","pages":""},"PeriodicalIF":0.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70817693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Pushkin, Olga Igorevna Chistohina, Amina Islyamovna Turalieva, Svetlana Ruslanovna Subaeva, Diana Armenovna Karapetyan, Alexandra Alexandrovna Romanova, Yulia Alexandrovna Zhatko
{"title":"The Use of Microcomputed Tomography to Study the Anatomical Features of the Body","authors":"S. Pushkin, Olga Igorevna Chistohina, Amina Islyamovna Turalieva, Svetlana Ruslanovna Subaeva, Diana Armenovna Karapetyan, Alexandra Alexandrovna Romanova, Yulia Alexandrovna Zhatko","doi":"10.51847/hhwabnfpzu","DOIUrl":"https://doi.org/10.51847/hhwabnfpzu","url":null,"abstract":"","PeriodicalId":46106,"journal":{"name":"International Journal of Pharmaceutical Research and Allied Sciences","volume":"1 1","pages":""},"PeriodicalIF":0.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70822439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The present research determined how the anticoagulant drug Heparin caused osteoporosis in rats and how Taraxacum officinale and/or vitamins can prevent it (C, K). Fifty female Wester albino rats were used in the 30-day study. They were placed into five groups. In the heparin-treated group, bone-specific alkaline phosphatase (ALP), osteocalcin (CO), deoxypyridinoline (DPD), and tartrate-resistant acid phosphatase (TRAP) were significantly increased in contrast to the control group. Taraxacum officinale and/or Vitamins (C, K) co-treatment of rats receiving heparin significantly reversed the declines in the examined parameters and the histomorphologic bone tissue images. In conclusion, the data showed that Taraxacum officinale and /or Vitamins (C, K) could protect the bone tissues from the damaging impact of heparin, which was more pronounced in rats treated with the combination of the two agents Taraxacum officinale and Vitamins (C, K). The current study may support the utilization of this combination as a promising therapy to alleviate the adverse of the anticoagulant
{"title":"Roles for Taraxacum officinale and Vitamins (C, K) on Bone Formation and Resorption Heparin-Induced in Rats","authors":"Amani Mohammad Alfaifi, M. Tashkandi, J. Yousef","doi":"10.51847/jzj0vbvtxp","DOIUrl":"https://doi.org/10.51847/jzj0vbvtxp","url":null,"abstract":"The present research determined how the anticoagulant drug Heparin caused osteoporosis in rats and how Taraxacum officinale and/or vitamins can prevent it (C, K). Fifty female Wester albino rats were used in the 30-day study. They were placed into five groups. In the heparin-treated group, bone-specific alkaline phosphatase (ALP), osteocalcin (CO), deoxypyridinoline (DPD), and tartrate-resistant acid phosphatase (TRAP) were significantly increased in contrast to the control group. Taraxacum officinale and/or Vitamins (C, K) co-treatment of rats receiving heparin significantly reversed the declines in the examined parameters and the histomorphologic bone tissue images. In conclusion, the data showed that Taraxacum officinale and /or Vitamins (C, K) could protect the bone tissues from the damaging impact of heparin, which was more pronounced in rats treated with the combination of the two agents Taraxacum officinale and Vitamins (C, K). The current study may support the utilization of this combination as a promising therapy to alleviate the adverse of the anticoagulant","PeriodicalId":46106,"journal":{"name":"International Journal of Pharmaceutical Research and Allied Sciences","volume":"1 1","pages":""},"PeriodicalIF":0.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70826071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abdulaziz Abdullah Almusalam, N. Abdullah, M. Alshammari
{"title":"Updates on the Association between Obesity and Migraine: Systematic Review of Observational Studies","authors":"Abdulaziz Abdullah Almusalam, N. Abdullah, M. Alshammari","doi":"10.51847/r9e9inze8d","DOIUrl":"https://doi.org/10.51847/r9e9inze8d","url":null,"abstract":"","PeriodicalId":46106,"journal":{"name":"International Journal of Pharmaceutical Research and Allied Sciences","volume":"1 1","pages":""},"PeriodicalIF":0.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70832496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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