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Local governments and community-based rehabilitation for developmental disabilities: leaving no one behind. 地方政府和以社区为基础的发育性残疾康复:不让任何人掉队。
IF 1.4 Pub Date : 2023-03-21 DOI: 10.5588/pha.22.0027
P Jose, S S Kumar, B A Chandru, S Sundaram, S M Vijayanand, V R Kutty, R P Varma

Setting: The BUDS (not an acronym) institutions comprise a community-based rehabilitation initiative for children and families affected by developmental disabilities in Kerala, India.

Objective: To explore the role of local governments in the establishment and functioning of BUDS institutions.

Design: We used qualitative approaches comprising document review and in-depth interviews with trainers, parents of children with developmental disabilities and elected representatives.

Results: BUDS was created by Kudumbasree, a decentralised women empowerment and poverty alleviation initiative. Our findings illustrate the role of local governments in facilitating expansion through the establishment of infrastructure, therapy equipment, transportation and financial allocation for these, as well as through the development of human resources, assistance with enrolment for financial assistance and insurance programmes, and coordination with education and health sectors. Programme implementation varied considerably regarding available infrastructure, staffing and services among the institutions studied. The institutions were physically closed during the COVID-19 pandemic but continued to function in alternative ways.

Conclusion: Despite variable implementation, local governments have supported the expansion of BUDS institutions, thereby creating more spaces for inclusive and integrated education and rehabilitation of persons with disabilities in Kerala. The expansion over the past two decades and measures during the COVID-19 pandemic suggest resilience and sustainability of the model.

背景:在印度喀拉拉邦,BUDS(不是缩写)机构组成了一个以社区为基础的康复倡议,旨在为受发育性残疾影响的儿童和家庭提供帮助。目的:探讨地方政府在基层医疗服务机构的建立和运作中的作用。设计:我们采用定性方法,包括文献回顾和对培训师、发育障碍儿童家长和当选代表的深度访谈。结果:BUDS由Kudumbasree创建,这是一个分散的妇女赋权和扶贫倡议。我们的研究结果表明,地方政府通过建立基础设施、治疗设备、运输和财政拨款,以及通过开发人力资源、协助参加财政援助和保险方案,以及与教育和卫生部门协调,在促进扩大方面发挥了作用。所研究的各机构在现有的基础设施、工作人员和服务方面的方案执行情况差别很大。这些机构在2019冠状病毒病大流行期间实际关闭,但继续以其他方式运作。结论:尽管实施情况不尽相同,但地方政府支持扩大BUDS机构,从而为喀拉拉邦的包容性和综合教育和残疾人康复创造了更多空间。过去20年的扩张和2019冠状病毒病大流行期间的措施表明,该模式具有复原力和可持续性。
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引用次数: 0
Palliative care management committees: a model of collaborative governance for primary health care. 姑息治疗管理委员会:初级卫生保健协作治理模式。
IF 1.4 Pub Date : 2023-03-21 DOI: 10.5588/pha.22.0028
A Kochuvilayil, S Rajalakshmi, A Krishnan, S M Vijayanand, V R Kutty, T Iype, R P Varma

Setting: The community-based primary palliative care programme in Kerala, India, has received international acclaim. Programme functioning is supported through Palliative Care Management Committees (PMCs) at the local government (LG) level.

Objective: To study the functioning of the PMCs within the decentralised governance space to identify achievements, gaps and notable innovations.

Design: This qualitative study included seven key informant interviews (KIIs), 28 in-depth interviews and a review of relevant publicly available policies and documents. Major themes were recognised from the KII transcripts. Codes emerging from the document review and in-depth interview transcripts were mapped into the identified thematic areas.

Results: Successful PMCs raised resources like money, human resource, equipment, had good skilled care options for symptom relief and facilitated reduced out-of-pocket expenditure by providing home care and free medicines, and improved access to interventions that addressed the social determinants of suffering like poverty. PMCs had varying managerial and technical capacities. In some LGs, the programme was weak and mostly limited to the supply of medicines, basic aids and appliances to patients' homes.

Conclusion: Despite varied implementation patterns, PMCs in Kerala are examples of state-supported, community-owned care initiatives, that can potentially address medical and social determinants of suffering.

环境:印度喀拉拉邦以社区为基础的初级姑息治疗方案获得了国际赞誉。方案的运作是通过地方政府一级的姑息治疗管理委员会来支持的。目的:研究分散治理空间中pmc的功能,以确定成就、差距和显著创新。设计:本定性研究包括7次关键信息提供者访谈(KIIs)、28次深度访谈以及对相关公开政策和文件的回顾。主要的主题是从KII的成绩单中识别出来的。从文件审查和深入访谈笔录中产生的代码已映射到确定的专题领域。结果:成功的pmc筹集了资金、人力资源、设备等资源,提供了缓解症状的良好熟练护理选择,并通过提供家庭护理和免费药物促进了自付支出的减少,并改善了获得干预措施的机会,解决了贫困等痛苦的社会决定因素。私营企业的管理和技术能力各不相同。在一些地方政府,方案很薄弱,主要限于向病人家中提供药品、基本的辅助设备和器具。结论:尽管实施模式各不相同,但喀拉拉邦的pmc是国家支持、社区拥有的护理倡议的例子,可以潜在地解决造成痛苦的医疗和社会决定因素。
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引用次数: 0
Pooling sputum samples for Xpert® MTB/RIF and Xpert® Ultra testing for TB diagnosis. 集中痰液样本进行 Xpert® MTB/RIF 和 Xpert® Ultra 检测,以诊断结核病。
IF 1.3 Q4 RESPIRATORY SYSTEM Pub Date : 2023-03-21 DOI: 10.5588/pha.22.0052
J S Bimba, O A Adekeye, V Iem, T T Eliya, I Osagie, K Kontogianni, T Edwards, J Dodd, S B Squire, J Creswell, L E Cuevas

Background: The use of molecular amplification as-says for TB diagnosis is limited by their costs and cartridge stocks. Pooling multiple samples to test them together is reported to have similar accuracy to individual testing and to save costs.

Methods: Two surveys of individuals with presumptive TB were conducted to assess the performance of pooled testing using Xpert® MTB/RIF (MTB/RIF) and Xpert® Ultra (Ultra).

Results: A total of 500 individuals were tested using MTB/RIF, with 72 (14.4%) being MTB-positive. The samples were tested in 125 pools, with 50 pools having ⩾1 MTB-positive and 75 only MTB-negative samples: 46/50 (92%, 95% CI 80.8-97.8) MTB-positive pools tested MTB-positive and 71/75 (94.7%, 95% CI 86.9-98.5) MTB-negative pools tested MTB-negative in the pooled test (agreement: 93.6%, κ = 0.867). Five hundred additional samples were tested using Ultra, with 60 (12%) being MTB-positive. Samples were tested in 125 pools, with 42 having ⩾1 MTB-positive and 83 only MTB-negative samples: 35/42 (83.6%, 95% CI 68.6-93.0) MTB-positive pools tested MTB-positive and 82/83 (98.8%, 95% CI 93.5-100.0) MTB-negative pools tested MTB-negative in the pooled test (agreement: 93.6%, κ = 0.851; P > 0.1 between individual and pooled testing). Pooled testing saved 35% (MTB/RIF) and 46% (Ultra) of cartridges.

Conclusions: Pooled and individual testing has a high level of agreement and improves testing efficiency.

背景:分子扩增技术在结核病诊断中的应用受到成本和试剂盒库存的限制。据报道,将多个样本集中在一起进行检测与单独检测具有相似的准确性,并能节省成本:方法:对推定肺结核患者进行了两次调查,以评估使用 Xpert® MTB/RIF(MTB/RIF)和 Xpert® Ultra(Ultra)进行联合检测的效果:共有 500 人接受了 MTB/RIF 检测,其中 72 人(14.4%)为 MTB 阳性。这些样本在 125 个样本池中进行了检测,其中 50 个样本池中有⩾1 个 MTB 阳性样本,75 个样本池中只有 MTB 阴性样本:在联合检测中,46/50(92%,95% CI 80.8-97.8)个 MTB 阳性样本池检测出 MTB 阳性,71/75(94.7%,95% CI 86.9-98.5)个 MTB 阴性样本池检测出 MTB 阴性(一致性:93.6%,κ = 0.867)。使用 Ultra 检测了另外 500 份样本,其中 60 份(12%)为 MTB 阳性。对 125 个样本池中的样本进行了检测,其中 42 个样本 MTB 阳性,83 个样本 MTB 阴性:在联合检测中,35/42(83.6%,95% CI 68.6-93.0)个 MTB 阳性样本池检测出 MTB 阳性,82/83(98.8%,95% CI 93.5-100.0)个 MTB 阴性样本池检测出 MTB 阴性(一致性:93.6%,κ = 0.851;单个检测与联合检测之间的 P > 0.1)。联合检测节省了 35%(MTB/RIF)和 46%(Ultra)的试剂盒:结论:联合检测和个体检测具有高度的一致性,并能提高检测效率。
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引用次数: 0
Health inequities around gender, disability and internal migration: are local governments doing enough. 围绕性别、残疾和国内移徙的卫生不平等:地方政府做得够不够?
IF 1.4 Pub Date : 2023-03-21 DOI: 10.5588/pha.22.0032
M R Nair, S S Kumar, S S Babu, B A Chandru, K S Kunjumon, C S Divya, R P Varma

Setting: The Kerala health system in India has more than 25 years of decentralised implementation experience. Decentralization could assist in addressing health disparities such as gender, disability, and migration.

Objective: To explore how inequity issues comprising gender, disability and internal migrations were being addressed at present by the decentralised Kerala health system.

Design: Our approach was qualitative, using document review, key informant interviews and in-depth interviews with policy makers, health staff and other stakeholders.

Results: Gender aspects were incorporated into planning and budgeting, with 10% funds earmarked for women. Projects were gender-specific to women, and within conventional social roles of livelihood, welfare or reproductive health. Recently, transgender focused projects were also initiated. Schemes for people with disabilities remained welfare-centric and driven by top-down policies. The local governments performed beneficiary identification and benefit disbursal. Migrant health aspects were focused on infectious diseases surveillance and later living conditions of migrant workers.

Conclusion: The importance that health systems place on socioeconomic determinants of health and fundamental human rights is reflected in the health interventions for marginalised communities. In Kerala, there is now a passive application of central rules and a reluctance to utilise local platforms. Changing this is a necessary condition for achieving equal development.

环境:印度喀拉拉邦卫生系统有超过25年的分散实施经验。权力下放有助于解决诸如性别、残疾和移徙等保健差异。目的:探讨目前分散的喀拉拉邦卫生系统如何解决包括性别、残疾和内部移民在内的不平等问题。设计:我们的方法是定性的,使用文件审查、关键信息提供者访谈以及与决策者、卫生工作人员和其他利益攸关方的深入访谈。结果:性别方面被纳入规划和预算,10%的资金专门用于妇女。项目针对妇女的具体性别,并在生计、福利或生殖健康等传统社会角色范围内。最近,以跨性别者为重点的项目也开始了。残疾人计划仍然以福利为中心,由自上而下的政策驱动。地方政府进行受益人认定和福利发放。移徙工人健康方面的重点是传染病监测和移徙工人后来的生活条件。结论:卫生系统对健康和基本人权的社会经济决定因素的重视反映在对边缘化社区的卫生干预措施中。在喀拉拉邦,现在被动地执行中央规定,不愿利用地方平台。改变这种状况是实现平等发展的必要条件。
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引用次数: 1
The role of local governments in the implementation of evidence-based nutrition interventions in Kerala. 地方政府在喀拉拉邦实施循证营养干预措施中的作用。
IF 1.4 Pub Date : 2023-03-21 DOI: 10.5588/pha.22.0026
J R Jith, R Bedamatta, K Rajamohanan, L K R Itty Amma, T S Sumitha, C S Divya, R Sadanandan, T Iype

Objective: To study the involvement and influence of local participatory governments consisting of Panchayat Raj institutions (PRIs) in implementing evidence-based interventions for eliminating maternal and child undernutrition in the state of Kerala, India.

Methods: In-depth interviews were carried out among stakeholders in six selected local governments using a semi-structured questionnaire. Transcribed interviews were coded and thematically analysed.

Results: PRIs facilitated nutrition interventions through additional resource mobilisation, nutrition monitoring and surveillance, acting as a more approachable point of governance, utilising general acceptance to mobilise volunteers to tackle local challenges, enabling formal and informal platforms for community participation and spaces of co-creation. Changes in the attitude of different stakeholders, timely policy backing and support, and interconnections at the local level aided the process. Gaps exist in awareness creation, dietary diversification, feeding behaviours, maternal mental health, infrastructure development, monitoring of anthropometric indicators and planning for nutrition interventions during emergencies.

Conclusion: Results illustrate complex linkages PRIs have within the health system and how these linkages help in the implementation of interventions. The study explored previously identified pathways from the literature and identified additional pathways through which local participatory governance contributes to the successful implementation of nutrition interventions.

目的:研究印度喀拉拉邦由村务委员会(Panchayat Raj institutions, PRIs)组成的地方参与性政府在实施消除孕产妇和儿童营养不良的循证干预措施方面的参与和影响。方法:采用半结构化问卷,对选定的6个地方政府的利益相关者进行深度访谈。采访记录被编码并按主题进行分析。结果:prs通过额外的资源动员、营养监测和监督促进营养干预,作为一个更容易接近的治理点,利用普遍接受来动员志愿者应对当地挑战,为社区参与和共同创造空间提供正式和非正式的平台。不同利益相关者态度的变化、及时的政策支持和支持以及地方层面的相互联系都有助于这一进程。在提高认识、饮食多样化、喂养行为、产妇心理健康、基础设施发展、人体测量指标监测和紧急情况下营养干预措施规划方面存在差距。结论:结果说明了质量评价指标在卫生系统内的复杂联系,以及这些联系如何有助于实施干预措施。该研究探索了先前从文献中确定的途径,并确定了地方参与式治理有助于成功实施营养干预措施的其他途径。
{"title":"The role of local governments in the implementation of evidence-based nutrition interventions in Kerala.","authors":"J R Jith,&nbsp;R Bedamatta,&nbsp;K Rajamohanan,&nbsp;L K R Itty Amma,&nbsp;T S Sumitha,&nbsp;C S Divya,&nbsp;R Sadanandan,&nbsp;T Iype","doi":"10.5588/pha.22.0026","DOIUrl":"https://doi.org/10.5588/pha.22.0026","url":null,"abstract":"<p><strong>Objective: </strong>To study the involvement and influence of local participatory governments consisting of <i>Panchayat Raj</i> institutions (PRIs) in implementing evidence-based interventions for eliminating maternal and child undernutrition in the state of Kerala, India.</p><p><strong>Methods: </strong>In-depth interviews were carried out among stakeholders in six selected local governments using a semi-structured questionnaire. Transcribed interviews were coded and thematically analysed.</p><p><strong>Results: </strong>PRIs facilitated nutrition interventions through additional resource mobilisation, nutrition monitoring and surveillance, acting as a more approachable point of governance, utilising general acceptance to mobilise volunteers to tackle local challenges, enabling formal and informal platforms for community participation and spaces of co-creation. Changes in the attitude of different stakeholders, timely policy backing and support, and interconnections at the local level aided the process. Gaps exist in awareness creation, dietary diversification, feeding behaviours, maternal mental health, infrastructure development, monitoring of anthropometric indicators and planning for nutrition interventions during emergencies.</p><p><strong>Conclusion: </strong>Results illustrate complex linkages PRIs have within the health system and how these linkages help in the implementation of interventions. The study explored previously identified pathways from the literature and identified additional pathways through which local participatory governance contributes to the successful implementation of nutrition interventions.</p>","PeriodicalId":46239,"journal":{"name":"Public Health Action","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2023-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9983806/pdf/i2220-8372-13-s1-26.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9219720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluating TB diagnosis and care in the Union of the Comoros. 评估科摩罗联盟的结核病诊断和治疗。
IF 1.4 Pub Date : 2023-03-21 DOI: 10.5588/pha.22.0057
J Noeske, A Mzembaba, Y Assoumani, S Maoulida, A Makpenon

Setting: The Union of the Comoros has experienced a persistent notification gap in TB cases despite several strategic changes, including molecular diagnosis and contact investigation. We therefore performed a TB patient pathway analysis (PPA) under the National Tuberculosis Programme (NTP).

Objective: To assess the alignment of healthcare-seeking behaviour and TB service availability to clarify the reasons for these missing cases.

Design: Three primary data sources, including a national list of health facilities, TB surveillance data and care-seeking behaviour data, were analysed at the national and regional levels to determine access to TB diagnosis and the initial point of care-seeking. Summary data were visualised using the standardised PPA Wizard programme, and the analysis was completed using demographic and socio-economic data.

Results: At the initial point of care-seeking, 18% of patients had access to TB services, available only in nine centralised public health facilities. Furthermore, 30% of patients initially consulted in the informal sector and 45% in the formal public or private sector in health facilities, both of which lacked the capacity for TB diagnosis or first-line treatment.

Conclusion: The concentration of and limited access to TB services at the intermediate and central levels of care indicate a need for decentralisation efforts.

背景:尽管进行了包括分子诊断和接触者调查在内的若干战略调整,科摩罗联盟在结核病病例通报方面一直存在差距。因此,我们在国家结核病规划(NTP)下进行了结核病患者途径分析(PPA)。目的:评估求医行为与结核病服务可得性的一致性,以澄清这些缺失病例的原因。设计:在国家和区域两级分析了三个主要数据来源,包括国家卫生设施清单、结核病监测数据和求医行为数据,以确定获得结核病诊断的可及性和最初的求医点。使用标准化PPA Wizard程序将汇总数据可视化,并使用人口统计和社会经济数据完成分析。结果:在最初的求诊点,18%的患者可以获得结核病服务,这些服务仅在9个集中的公共卫生设施中提供。此外,30%的患者最初在非正规部门就诊,45%在卫生设施的正规公共或私营部门就诊,这两家机构都缺乏结核病诊断或一线治疗的能力。结论:结核病服务在中级和中央护理水平的集中和有限的可及性表明需要进行分散努力。
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引用次数: 0
Decentralisation, health and Sustainable Development Goal 3. 权力下放、卫生和可持续发展目标3。
IF 1.4 Pub Date : 2023-03-21 DOI: 10.5588/pha.22.0034
R Anju, R Sadanandan, K Vijayakumar, V Raman Kutty, B Soman, R M Ravindran, R P Varma

Setting: Kerala State, India, implemented decentralising reforms of healthcare institutions 25 years ago through transfer of administrative control and a sizeable share of the financial allocation.

Objective: To describe the main impacts of decentralisation in Kerala on local policy formulation, programme implementation and service delivery for sustainable health systems.

Design: This was part of a broader qualitative study on decentralisation and health in Kerala. We conducted 25 in-depth interviews and reviewed 31 government orders or policy documents, five related transcripts and five thematic reports from the main study.

Results: Liaising between health system and local governments has improved over time. A shift from welfare-centric projects to infrastructure, human resources and services was evident. Considerable heterogeneity existed due to varying degrees of involvement, capacity, resources and needs of the community. State-level discourse and recent augmentation efforts for moving towards the UN Sustainable Development Goals (SDGs) strongly uphold the role of local governments in planning, financing and implementation.

Conclusion: The 25-year history of decentralised healthcare administration in Kerala indicates both successes and failures. Central support without disempowering the local governments can be a viable option to allow flexible decision-making consistent with broader system goals.

背景:25年前,印度喀拉拉邦通过转移行政控制和分配相当大份额的财政拨款,对医疗机构实施了下放改革。目的:描述喀拉拉邦权力下放对地方政策制定、项目实施和可持续卫生系统服务提供的主要影响。设计:这是关于喀拉拉邦权力下放与健康的更广泛定性研究的一部分。我们进行了25次深度访谈,审查了31份政府命令或政策文件、5份相关成绩单和5份主要研究的专题报告。结果:随着时间的推移,卫生系统与地方政府之间的联系有所改善。从以福利为中心的项目向基础设施、人力资源和服务的转变是显而易见的。由于社区的参与程度、能力、资源和需要各不相同,因此存在相当大的异质性。为实现联合国可持续发展目标(sdg),国家层面的讨论和最近的加强努力强烈支持地方政府在规划、融资和实施方面的作用。结论:喀拉拉邦25年的分散医疗管理历史表明既有成功也有失败。在不剥夺地方政府权力的情况下,中央支持是一个可行的选择,可以使决策灵活,与更广泛的系统目标相一致。
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引用次数: 1
Perspectives of TB survivors and policymakers on post-TB disability. 结核病幸存者和政策制定者对结核病后残疾的看法。
IF 1.4 Pub Date : 2023-03-21 DOI: 10.5588/pha.22.0050
O Nkereuwem, E Nkereuwem, O Owolabi, P Johm, U Egere, K Mortimer, B Kampmann, T Togun

Background: An international multistakeholder participatory workshop was hosted in the Gambia, West Africa, in November 2021.

Objectives: To explore the experiences, challenges and recommendations of workshop participants on health and wellbeing after TB treatment.

Methods: An exploratory, descriptive, qualitative approach was used for data collection through facilitator-guided group discussions. Workshop participants included adolescent and adult TB survivors, and representatives of TB advocacy groups and the policy sector. Discussions were audio-recorded and transcribed verbatim, and the data were analysed using a deductive thematic approach.

Results: Overall, 38 participants (22 women) from six West African countries participated in the workshop, comprising 33 TB survivors and advocacy group representatives and 5 participants from the policy sector. Although some TB survivors noted improved ability to carry out physical activities, others continued to experience detrimental effects on their family life, social interactions, physical health and ongoing stigma. Policymakers emphasised the lack of data and clear guidelines on post-TB disability.

Conclusions: Some TB survivors continue to suffer detrimental effects of the illness even after treatment completion. However, available data on post-TB disability is inadequate to support policy adoption. Therefore, there is an urgent need for increased advocacy, awareness and research to bridge knowledge gaps.

背景:2021年11月在西非冈比亚举办了一次多利益攸关方参与国际研讨会。目的:探讨研讨会参与者在结核病治疗后的健康和福祉方面的经验、挑战和建议。方法:采用探索性、描述性、定性的方法,通过主持人引导的小组讨论收集数据。讲习班的参加者包括青少年和成年结核病幸存者,以及结核病倡导团体和政策部门的代表。讨论被录音并逐字抄录,数据用演绎主题方法进行分析。结果:总共有来自6个西非国家的38名参与者(22名女性)参加了研讨会,其中包括33名结核病幸存者和倡导团体代表,以及5名来自政策部门的参与者。虽然一些结核病幸存者指出进行体育活动的能力有所提高,但其他人的家庭生活、社会交往、身体健康和持续的耻辱继续受到不利影响。决策者强调缺乏关于结核病后致残的数据和明确的指导方针。结论:一些结核病幸存者甚至在治疗完成后继续遭受疾病的有害影响。然而,现有的结核病后残疾数据不足以支持政策的采纳。因此,迫切需要加强宣传、提高认识和研究,以弥合知识差距。
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引用次数: 2
Role of decentralised governance in implementing the National AIDS Control Programme in Kerala. 权力下放管理在实施喀拉拉邦国家艾滋病控制计划中的作用。
IF 1.3 Q4 RESPIRATORY SYSTEM Pub Date : 2023-03-21 DOI: 10.5588/pha.22.0029
R Kamala, R M Ravindran, R A Krishnan, S Nair, R P Varma, S Srilatha, T Iype, K Vidhukumar

Setting: In alignment with the UN Sustainable Development Goals (SDGs), Kerala State in India aims to end the HIV/AIDS epidemic, using its strong background in local governance to implement the National AIDS Control Programme (NACP).

Objective: To examine the role of local governments in the implementation of NACP in tune with SDGs.

Design: We conducted a state-wide exploratory study using document reviews, key informant and in-depth interviews, which were analysed thematically.

Results: Four overarching themes that emerged were 1) preparation for programme implementation, 2) positive impact of local government involvement, 3) convergence with other organisations, and 4) barriers to implementation. Local government commitment to implementing the programme was evidenced by their adoption of the HIV/AIDS policy, facilitative interdepartmental coordination and local innovations. Interventions focused on improving awareness about the disease and treatment, and social, financial and rehabilitative support, which were extended even during the COVID-19 pandemic. Fund shortages and poor visibility of the beneficiaries due to preference for anonymity were challenges to achieving the expected outcomes.

Conclusion: The NACP is ably supported by local governments in its designated domains of interventions, prevention, treatment, and care and support. The programme can achieve its target to end the AIDS epidemic by overcoming the stigma factor, which still prevents potential beneficiaries from accessing care.

背景:为了与联合国可持续发展目标(SDGs)保持一致,印度喀拉拉邦利用其在地方治理方面的强大背景,实施了国家艾滋病控制计划(NACP),旨在结束艾滋病毒/艾滋病的流行:研究地方政府在根据可持续发展目标实施国家艾滋病控制计划中的作用:设计:我们在全州范围内开展了一项探索性研究,采用了文件审查、关键信息提供者和深入访谈等方法,并对这些方法进行了专题分析:出现了四个重要主题:1)计划实施的准备工作;2)地方政府参与的积极影响;3)与其他组织的融合;4)实施障碍。地方政府对实施该计划的承诺体现在他们采纳了艾滋病毒/艾滋病政策、促进了部门间协调和地方创新。干预措施的重点是提高对疾病和治疗的认识,以及提供社会、财政和康复支持,甚至在 COVID-19 大流行期间也提供了这些支持。资金短缺和由于不愿透露姓名而导致的受益人能见度低是实现预期成果所面临的挑战:国家艾滋病防治计划在其指定的干预、预防、治疗、护理和支持领域得到了地方政府的大力支持。该计划可以通过克服仍然阻碍潜在受益人获得护理的污名化因素,实现其结束艾滋病流行的目标。
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引用次数: 0
Breakthrough TB among people living with HIV on TB preventive therapy. 艾滋病毒感染者结核病预防治疗取得突破性进展。
IF 1.4 Pub Date : 2022-12-21 DOI: 10.5588/pha.22.0016
S Nyangu, M Kagujje, I Mwaba, D Luhanga, R Hambwalula, S Maliko, T Mushili, E Mwamba, Mukaba Mulai, Monde Muyoyeta

Background: Zambia has an estimated TB incidence of 319/100,000 population and a HIV prevalence of 11.1%. In 2020, only 49% of new people living with HIV (PLHIV) received TB preventive therapy (TPT) in Zambia. Misconceptions about the reliability of symptom screening and drug resistance among people who develop TB while on TPT are barriers to TPT scale-up. We determined the incidence and predictors of breakthrough TB during TPT among PLHIV in Zambia.

Method: This was a retrospective analysis of routine TPT programme data among PLHIV collected between October 2016 and October 2019 from select primary health facilities in Zambia.

Results: Of 48,581 PLHIV enrolled on TPT, 130 (0.3%) developed breakthrough TB during TPT. Of the 130, 90 client records were accessed. The median age of the breakthrough TB cases was 35 years; 68% were males. Overall, 96% of the breakthrough TB cases had been on antiretroviral therapy (ART) for ⩽3 months; 24% were symptomatic at the beginning of TPT, 22% were asymptomatic and others had missing data. Of the 130 breakthrough TB cases, 79% developed TB in the first month after TPT initiation. The median time to TB diagnosis was 10 days (IQR 4-16).

Conclusion: Breakthrough TB during TPT is rare among PHLIV on ART, and very rare after the first month of TPT initiation. It should therefore not be a barrier to TPT scale-up.

背景:赞比亚估计结核病发病率为319/10万人,艾滋病毒患病率为11.1%。2020年,赞比亚只有49%的新发艾滋病毒感染者接受了结核病预防治疗。对症状筛查的可靠性和在接受TPT治疗期间出现结核病患者的耐药性的误解是扩大TPT治疗的障碍。我们确定了赞比亚艾滋病毒感染者TPT治疗期间突破性结核病的发病率和预测因素。方法:回顾性分析2016年10月至2019年10月从赞比亚选定的初级卫生机构收集的艾滋病毒感染者常规TPT规划数据。结果:在接受TPT治疗的48,581名PLHIV患者中,130名(0.3%)在TPT治疗期间发展为突破性结核病。在这130条记录中,有90条客户记录被访问。突破结核病例的中位年龄为35岁;68%是男性。总体而言,96%的突破性结核病例已接受抗逆转录病毒治疗(ART)≥3个月;24%的患者在TPT开始时有症状,22%的患者无症状,其他患者数据缺失。在130例突破性结核病例中,79%在开始TPT治疗后的第一个月发生结核。到结核诊断的中位时间为10天(IQR 4-16)。结论:在接受抗逆转录病毒治疗的PHLIV患者中,TPT治疗期间出现突破结核的情况非常罕见,而在TPT治疗开始的第一个月后更是非常罕见。因此,它不应成为扩大TPT的障碍。
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